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药学服务与研究最新文献

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Study on efficacy and safety of doxofylline for preventing ticagrelor-related dyspnea in patients with chronic obstructive pulmonary disease 多索茶碱预防慢性阻塞性肺疾病患者替格瑞洛相关性呼吸困难的有效性和安全性研究
Q4 Health Professions Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200607
Yuefeng Wang, Q. Gao, Xi Liu
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引用次数: 0
Establishment of the indicator system for clinical rationality evaluation of antitumor drugs by the Delphi method 德尔菲法建立抗肿瘤药物临床合理性评价指标体系
Q4 Health Professions Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200601
Yan Li, Weiyi Feng, W. Mao, Jian-hui Yan, Lin Wu, Xiaomin Si
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引用次数: 0
Practice of online consultation of pharmacists during epidemic prevention of Corona Virus Disease-2019 and prospect of refined pharmaceutical care 2019冠状病毒病防疫药师在线咨询实践与精细化药学服务展望
Q4 Health Professions Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200616
Yeyan Hu, Yan Pan, Mengwan Zhang, Jian-Guang Yu
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引用次数: 0
Investigation on pharmacy administration in primary medical institutions and improvement of pharmacists’ skills 基层医疗机构药学管理现状调查与药师队伍建设
Q4 Health Professions Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200620
Dayong Zhou, Shang-xing Guo, Aina Liu, Li Zhou, Shan Jiang
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引用次数: 0
Analysis of typical cases of irrational use of immunosuppressants 不合理使用免疫抑制剂的典型案例分析
Q4 Health Professions Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200611
Quan-jing Chen, Qinyong Shen, Zhengbiao Ni, Hongtao Song
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引用次数: 0
Determination of linezolid concentration in the plasma of the patients from the Department of Hematology by UPLC method UPLC法测定血液科患者血浆中利奈唑胺浓度
Q4 Health Professions Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200603
C. Ming, Yuefan Shen, Guorong Fan, Yuanjun Tang
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引用次数: 0
Pharmaceutical practice and experience of clinical pharmacists engaged in the treatment of cancer pain 癌症疼痛临床药师的药学实践与体会
Q4 Health Professions Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200612
Quan Hui, Junmei Song, Xin Liu, Yang Yang, Chun-ling Tang
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引用次数: 1
Exploration of the teaching mode of therapeutic drug monitoring in hospital pharmacy for pharmaceutical undergraduates under the guidance of micro film 微电影指导下药学本科生医院药学治疗药物监测教学模式的探索
Q4 Health Professions Pub Date : 2020-12-31 DOI: 10.5428/PCAR20200605
Xuebin Wang, Jing Tian, Nan Ding, Jiao Qian, Yunyun Yang, Zhuo Wang
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引用次数: 0
Construction of a platform for the transformation from general pharmacists to information pharmacists using the quality control circle 利用质量控制圈构建从普通药剂师向信息药剂师转变的平台
Q4 Health Professions Pub Date : 2020-10-31 DOI: 10.5428/PCAR20200511
H. Peng, Ru Shi, Hongju Lin, Xinrong Wu, Bai Qin
Objective: To explore and construct a platform for the transformation from general pharmacists to information pharmacists using quality control circle(QCC) activities.Methods: The QCC activities were applied to the whole training process of information pharmacists.Training started through the approach of having the pharmacists learn programming sentences,and program writing was finally completed after continuous exploration.Results: Through QCC activities,3 information pharmacists were initially trained,the writing of 2 programs were completed and a set of standard training profiles was summarized.Conclusion: The QCC activities could be used for pharmacy management and personnel training.It is particularly the case when more difficult targets are set for the work.Compared with the general team,the team implementing the QCC is more resolute and clearer in work goals and more liable to complete the project.
目的:利用质量控制圈(QCC)活动,探索并构建一个由全科药剂师向信息药剂师转变的平台。方法:将QCC活动应用于信息药师培训的全过程。培训从让药剂师学习编程语句开始,经过不断探索,程序编写终于完成。结果:通过QCC活动,初步培训了3名信息药剂师,完成了2个项目的编写,总结了一套标准的培训档案。结论:QCC活动可用于药学管理和人员培训。当为工作设定更困难的目标时,情况尤其如此。与一般团队相比,实施QCC的团队在工作目标上更坚决、更清晰,更有责任完成项目。
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引用次数: 0
Pharmaceutical care of a patient with severe hand-foot skin reactions induced by apatinib mesylate and literature review 甲磺酸阿帕替尼引起严重手足皮肤反应的药物治疗及文献复习
Q4 Health Professions Pub Date : 2020-10-31 DOI: 10.5428/PCAR20200514
Doudou He, Xiaochun Zheng
Objective: To explore pharmaceutical care methods for hand-foot skin reactions induced by apatinib mesylate tablets,so as to provide reference for rational use of drugs clinically.Methods: A case of severe hand-foot skin reactions induced by apatinib mesylate tablets in the treatment of advanced gastric cancer was reported.The clinical manifestations,treatment principles and possible mechanism of the disease were reviewed in combination with literature.Results: Most of the hand-foot skin reactions caused by oral administration of apatinib mesylate tablets occurred 2-3 weeks after medication,mostly with clinical manifestations of erythema in palms,fingers,joints and toes accompanied with swelling and pain,as well as hyperkeratosis of the skin with paresthesia.The occurrence of hand-foot skin reactions caused by apatinib mesylate tablets were associated with such factors as inhibition of vascular endothelial growth factor and decreased capillary repair capacity and other factors.To prevent its occurrence,daily life care,adjustment of the dosage of apatinib mesylate,external application of topical emollients containing urea,analgesics and external use of super-potent topical corticosteroids could obviously reduce the severity of hand-foot skin reactions.If hand-foot skin reactions were recurrent and difficult to control,replacement with other targeted drugs could be considered.Conclusion: In the application of apatinib mesylate tablets,hand-foot skin reactions were not rare.Close attention should be paid to drug monitoring on the part of clinicians and clinical pharmacists,so that the occurrence of adverse drug reactions could be reduced.In case there were hand-foot skin reactions,timely symptomatic treatment and close observation should be given,so as to improve the safety and efficacy of drug therapy.
目的:探讨甲磺酸阿帕替尼片引起手足皮肤反应的药物治疗方法,为临床合理用药提供参考。方法:报告甲磺酸阿帕替尼片治疗晚期癌症引起严重手足皮肤反应1例。结合文献对该病的临床表现、治疗原则及可能的发病机制进行了综述。结果:口服甲磺酸阿帕替尼片引起的手足皮肤反应多发生在用药后2-3周,临床表现多为手掌、手指、关节、脚趾红斑伴肿胀疼痛,皮肤角化过度伴感觉异常。甲磺酸阿帕替尼片引起手足皮肤反应的发生与抑制血管内皮生长因子、降低毛细血管修复能力等因素有关。为预防其发生,日常生活护理、调整甲磺酸阿帕替尼剂量、外用含尿素的局部润肤剂、镇痛剂和外用超强效局部皮质类固醇可明显减轻手足皮肤反应的严重程度。如果手足皮肤反应复发且难以控制,可以考虑用其他靶向药物替代。结论:甲磺酸阿帕替尼片应用中,手足皮肤反应并不少见。临床医生和临床药师应密切关注药物监测,以减少药物不良反应的发生。如出现手足皮肤反应,应及时对症治疗并密切观察,以提高药物治疗的安全性和疗效。
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引用次数: 1
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