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Ophthalmology Practice-Related Factors and Patient Loyalty: Mediating Role of Patient Satisfaction 眼科诊疗相关因素与患者忠诚度:患者满意度的中介作用
IF 2.2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-09 DOI: 10.2147/ppa.s461314
Abdulmohsen Almulhim, Abdullah Fahad AlMulhim
Background: In the current period, competition among the healthcare sector has increased and healthcare providers try to get loyalty and satisfy the patients by establishing different strategies.
Purpose: : This current study aims to discover ophthalmology practice-related factors and patient loyalty and to analyze the mediating role of patient satisfaction in private ophthalmology services in various private centers in the Kingdom of Saudi Arabia.
Methods: : The nature of the study is quantitative, and data is collected with a questionnaire. We used a pre-tested questionnaire that was divided into different sections assessing ophthalmology practice-related factors, patient satisfaction, and patient loyalty. These were measured using a 5-point Likert scale, focusing on financial aspects, access to facilities, staff services, and ophthalmologist services. Further, the smartPLS technique was used to extract the results by using SmartPLS.
Results: : The analysis sample size consisted of 323 participants from Saudi Arabia. The results found that ophthalmologist service has a positive relationship with patient satisfaction (β= 0.369, p = 0.000) as well as patient loyalty (β= 0.234, p = 0.004), but there are some ophthalmology practice-related factors such as financial aspects, access and facilities, and staff service, which showed no relationship with patient loyalty but a positive relationship with patient satisfaction. Further analysis found that patient satisfaction as a mediator has a positive relationship between ophthalmology practice-related factors, namely, ophthalmologist service (β= 0.228, P= 0.000), financial aspects (β= 0.102, p = 0.019), access and facilities (β= 0.109, p =0.000), and staff service (β= 0.188, p = 0.000) with patient loyalty.
Conclusion: : The present study findings reveal the importance of focused patient satisfaction improvements in enhancing patient loyalty within ophthalmological clinic settings in Saudi Arabia. Furthermore, we recommend future exploratory prospective research to find the satisfaction and loyalty factors that change over a period of time.

背景:在当前时期,医疗行业之间的竞争日益激烈,医疗服务提供者试图通过制定不同的策略来获得患者的忠诚度和满意度:本研究旨在发现眼科实践相关因素和患者忠诚度,并分析患者满意度在沙特阿拉伯王国各私立眼科中心私立眼科服务中的中介作用:研究性质为定量研究,通过问卷收集数据。我们使用了一份预先测试过的调查问卷,该问卷分为不同部分,分别评估眼科诊疗相关因素、患者满意度和患者忠诚度。这些因素均采用 5 点李克特量表进行测量,重点关注财务方面、设施使用、员工服务和眼科医生服务。此外,还使用了 SmartPLS 技术来提取结果:分析样本量包括来自沙特阿拉伯的 323 名参与者。结果发现,眼科医生服务与患者满意度(β= 0.369,p = 0.000)和患者忠诚度(β= 0.234,p = 0.004)呈正相关,但一些与眼科诊疗相关的因素,如财务方面、交通和设施、员工服务等,与患者忠诚度没有关系,但与患者满意度呈正相关。进一步分析发现,患者满意度作为中介因素,在眼科医生服务(β= 0.228,P= 0.000)、财务方面(β= 0.102,P= 0.019)、交通和设施(β= 0.109,P=0.000)、员工服务(β= 0.188,P= 0.000)等眼科诊疗相关因素与患者忠诚度之间存在正相关关系:本研究结果表明,在沙特阿拉伯的眼科诊所中,集中提高患者满意度对于提高患者忠诚度非常重要。此外,我们建议今后开展探索性前瞻研究,以发现随时间推移而变化的满意度和忠诚度因素。
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引用次数: 0
Prevalence and Factors Associated with Adherence to Iron-Folic Acid Supplementation Among Pregnant Women in Eastern Sudan: A Cross-Sectional Study. 苏丹东部孕妇坚持补充铁-叶酸的普遍性及相关因素:一项横断面研究。
IF 2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-06 eCollection Date: 2024-01-01 DOI: 10.2147/PPA.S476738
Mustafa S Saeed, Gamal K Adam, Samah M Hussein, Nadiah AlHabardi, Ishag Adam

Purpose: The present study was conducted to determine the prevalence and factors associated with adherence to iron-folic acid supplementation (IFAS) among pregnant women in eastern Sudan.

Methods: A cross-sectional survey was conducted among pregnant women who obtained antenatal care (ANC) at Gadarif Maternal Hospital in eastern Sudan between May 1 and August 31, 2023. Face-to-face interview questionnaires were used to gather sociodemographic, obstetric, and clinical data (age, parity, education, residence, and previous medical diseases). Knowledge of anemia and IFAS was assessed. Multivariate analysis was performed to adjust for confounders.

Results: A total of 568 pregnant women were enrolled in the present study. Among them, 449 (79.0%) adhered to the IFAS. The multivariate analysis showed that the adjusted odds ratio (AOR) of IFAS adherence increased with ANC visits > 4 (AOR = 1.68, 95.0% CI = 1.01-2.77) and knowledge of anemia (AOR = 2.06, 95.0% CI = 1.437-3.276). In the univariate analysis, maternal occupation and knowledge of IFAS adherence were the only factors associated with IFAS adherence. Maternal age, parity, gestational age, education, residence, occupation, medical insurance, medical disease, and husband's occupation were not associated with IFAS. Forgetfulness (71.0%), frustration from taking many drugs (54.6%), and unpleasant tests of the supplement (50.7%) were the main reasons for not taking the IFAS.

Conclusion: About four out of five pregnant women adhered to the IFAS, indicating a good level of adherence, especially among women who attended more than four ANC visits and those with good knowledge of anemia. More attention is needed to encourage ANC to increase adherence to IFAS.

目的:本研究旨在确定苏丹东部孕妇中坚持服用铁-叶酸补充剂(IFAS)的患病率和相关因素:对 2023 年 5 月 1 日至 8 月 31 日期间在苏丹东部加达里夫妇产医院接受产前护理(ANC)的孕妇进行了横断面调查。调查采用面对面访谈问卷的形式,收集社会人口学、产科和临床数据(年龄、胎次、教育程度、居住地和既往病史)。还对贫血和 IFAS 的知识进行了评估。对混杂因素进行了多变量分析:本研究共招募了 568 名孕妇。结果:本研究共招募了 568 名孕妇,其中 449 人(79.0%)遵守了 IFAS。多变量分析显示,产前检查次数大于 4 次(AOR = 1.68,95.0% CI = 1.01-2.77)和对贫血的了解(AOR = 2.06,95.0% CI = 1.437-3.276)会增加遵守 IFAS 的调整赔率(AOR)。在单变量分析中,孕产妇的职业和对坚持 IFAS 的了解是唯一与坚持 IFAS 相关的因素。产妇年龄、胎次、胎龄、教育程度、居住地、职业、医疗保险、医疗疾病和丈夫的职业与 IFAS 无关。健忘(71.0%)、服用多种药物的挫败感(54.6%)和不愉快的补充剂测试(50.7%)是不服用 IFAS 的主要原因:结论:约五分之四的孕妇坚持服用 IFAS,这表明孕妇坚持服用的程度良好,尤其是在接受过四次以上产前检查的妇女和对贫血有充分了解的妇女中。需要更加重视鼓励产前检查,以提高对 IFAS 的依从性。
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引用次数: 0
Treatment Preferences of Adult Patients with Attention-Deficit/Hyperactivity Disorder - A Discrete Choice Experiment. 注意力缺陷/多动障碍成人患者的治疗偏好--离散选择实验。
IF 2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-06 eCollection Date: 2024-01-01 DOI: 10.2147/PPA.S467724
Jeff Schein, Martin Cloutier, Marjolaine Gauthier-Loiselle, Maryaline Catillon, Yan Meng, Beatrice Libchaber, Fanny Jiang, Ann Childress

Background: Understanding patient preferences for treatments may facilitate shared decision-making. This study assessed adult patient preferences for attention-deficit/hyperactivity disorder (ADHD) treatments in a sample of 600 patients in the United States (US).

Methods: A web-based discrete choice experiment (DCE) survey was conducted among treated adults with ADHD. Participants were recruited from Dynata's US panel (06/22/2023-07/06/2023). Attributes and levels, identified based on clinical inputs and published data, included efficacy and safety. Participants' preferences were estimated using conditional logistic regression. Willingness to trade-off and attributes' relative importance were calculated. Overall preferences for treatment profiles approximating centanafadine, lisdexamfetamine, atomoxetine, and viloxazine were estimated using adjusted total utilities. Results were stratified by current treatment status. Sensitivity analyses including participants who passed validity tests were conducted.

Results: Among the 600 participants (mean age 37.9 years; 66.2% female; 50.8% treated), all attributes had a statistically significant impact on preferences for ADHD treatments (p < 0.001); the most important attribute was improvement in ADHD symptoms (36%), followed by risks of nausea (25%), insomnia (20%), anxiety (8%), dry mouth (6%), and feeling jittery (5%). Together, safety attributes accounted for >60% of relative importance in decision-making. Participants were willing to forgo 0.59, 0.57, 0.49, 0.32, and 0.17 percentage points of symptom improvement to achieve one-percentage-point reduced risk of insomnia, nausea, anxiety, feeling jittery, and dry mouth, respectively. Centanafadine profile had consistently higher adjusted total utilities than its comparators. Similar results were obtained in the subgroup and sensitivity analyses.

Conclusion: Efficacy was the most important attribute for patients when making treatment decision, but taken together, AEs had greater relative importance than efficacy alone. Accordingly, a profile resembling that of centanafadine would be preferred by an average patient compared to key competitors due to its favorable safety profile. These findings may help improve treatment decision-making, enhance treatment satisfaction, and foster adherence.

背景:了解患者对治疗方法的偏好有助于共同决策。本研究以美国 600 名患者为样本,评估了成年患者对注意力缺陷/多动障碍(ADHD)治疗方法的偏好:在接受治疗的成人注意力缺陷/多动症患者中开展了一项基于网络的离散选择实验(DCE)调查。参与者是从 Dynata 的美国面板(06/22/2023-07/06/2023)中招募的。根据临床输入和公布的数据确定的属性和水平包括疗效和安全性。参与者的偏好使用条件逻辑回归进行估算。计算了权衡意愿和属性的相对重要性。使用调整后的总效用估算了对近似于仙那法定、利司他明、阿托西汀和维罗沙嗪的治疗方案的总体偏好。结果按当前治疗状态进行了分层。对通过有效性测试的参与者进行了敏感性分析:在 600 名参与者(平均年龄 37.9 岁;66.2% 为女性;50.8% 接受过治疗)中,所有属性对多动症治疗的偏好都有显著的统计学影响(P < 0.001);最重要的属性是多动症症状的改善(36%),其次是恶心(25%)、失眠(20%)、焦虑(8%)、口干(6%)和紧张(5%)的风险。安全属性在决策中的相对重要性合计超过 60%。参与者愿意放弃 0.59、0.57、0.49、0.32 和 0.17 个百分点的症状改善,以换取失眠、恶心、焦虑、烦躁不安和口干的风险降低一个百分点。圣他那定简介的调整后总效用一直高于其比较药。亚组分析和敏感性分析也得出了类似的结果:结论:疗效是患者做出治疗决定时最重要的因素,但综合来看,AEs的相对重要性高于疗效本身。因此,与主要竞争对手相比,普通患者更倾向于选择与 centanafadine 相似的药物,因为它具有良好的安全性。这些发现可能有助于改善治疗决策、提高治疗满意度并促进患者坚持治疗。
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引用次数: 0
"I Don't Feel Judged, I Don't Feel Less of a Person" - Engaged and Supportive Providers in the HIV Care Experiences of Black Sexual Minority Men Living with HIV. "我不觉得自己被评判,也不觉得自己不是一个人"--感染艾滋病毒的黑人性少数群体男性的艾滋病毒护理经历中,提供者的参与和支持。
IF 2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.2147/PPA.S467587
Kirstin Kielhold, Erik D Storholm, Hannah E Reynolds, Wilson Vincent, Daniel E Siconolfi, Susan M Kegeles, Lance Pollack, Chadwick K Campbell

Background: Black sexual minority men (BSMM) in the Southern region of the United States experience a disproportionate burden of HIV. Research findings suggest that having supportive patient-provider relationships are critical for sustained HIV care engagement. The present study explores the role of supportive healthcare providers in the care engagement among BSMM living with HIV (BSMM+) in the US South.

Methods: Semi-structured qualitative interviews were conducted with BSMM+ in Texas (n=27) to explore perceived barriers and facilitators of sustained care engagement. Interviews lasted 60 minutes on average, were transcribed, coded, and analyzed using applied thematic analysis.

Findings: Participants described how important having relationships with engaged and supportive HIV care and service providers is to sustained engagement in care and positive HIV clinical outcomes. Supportive providers were characterized as non-judgmental, meeting patients' needs, and making patients feel "seen". Less supportive providers were described as making their patients "feel like a number" and having lack of follow through on proposed support and resources. Supportive providers were associated with increased care engagement of their patients while less supportive providers often led to patients switching providers, losing touch with services, and getting off track with their care.

Discussion: We found that among BSMM+ an important facilitator of sustained care engagement was having positive, affirming, and knowledgeable healthcare providers, while negative and dismissive experiences with providers was a notable barrier to care engagement. This work highlights the need for a scale up of comprehensive, ongoing trainings in patient-centered and person-first communication for providers. Further, manageable provider caseloads can facilitate more thorough patient interactions where tailored HIV care and education can be provided in a safe and non-judgmental environment.

背景:美国南部地区的黑人性少数群体男性(BSMM)承受着不成比例的艾滋病负担。研究结果表明,患者与医疗服务提供者之间的支持性关系对于持续参与 HIV 护理至关重要。本研究探讨了支持性医疗服务提供者在美国南部感染 HIV 的 BSMM+ 患者(BSMM+)参与护理过程中的作用:方法:对得克萨斯州的 BSMM+ 进行了半结构化定性访谈(n=27),以探讨持续参与护理过程中感知到的障碍和促进因素。访谈平均持续 60 分钟,采用应用主题分析法进行转录、编码和分析:参与者描述了与参与并提供支持的艾滋病护理和服务提供者建立关系对于持续参与护理和取得积极的艾滋病临床结果有多么重要。支持性服务提供者的特点是不做评判、满足患者需求并让患者感觉 "被看见"。而支持性较差的医疗服务提供者则会让病人 "感觉自己是个数字",并且对病人提出的支持和资源建议缺乏跟进。支持性较强的医疗服务提供者会提高患者的护理参与度,而支持性较弱的医疗服务提供者往往会导致患者更换医疗服务提供者、与服务机构失去联系以及偏离护理轨道:我们发现,在 BSMM+ 中,拥有积极、肯定且知识渊博的医疗服务提供者是持续参与护理的重要促进因素,而与医疗服务提供者之间的负面和轻蔑经历则是参与护理的显著障碍。这项工作突出表明,有必要扩大对医疗服务提供者进行以患者为中心和以人为本的沟通方面的全面、持续培训的规模。此外,可控的医疗服务提供者工作量可以促进更全面的患者互动,从而在安全、无偏见的环境中提供量身定制的艾滋病护理和教育。
{"title":"\"I Don't Feel Judged, I Don't Feel Less of a Person\" - Engaged and Supportive Providers in the HIV Care Experiences of Black Sexual Minority Men Living with HIV.","authors":"Kirstin Kielhold, Erik D Storholm, Hannah E Reynolds, Wilson Vincent, Daniel E Siconolfi, Susan M Kegeles, Lance Pollack, Chadwick K Campbell","doi":"10.2147/PPA.S467587","DOIUrl":"10.2147/PPA.S467587","url":null,"abstract":"<p><strong>Background: </strong>Black sexual minority men (BSMM) in the Southern region of the United States experience a disproportionate burden of HIV. Research findings suggest that having supportive patient-provider relationships are critical for sustained HIV care engagement. The present study explores the role of supportive healthcare providers in the care engagement among BSMM living with HIV (BSMM+) in the US South.</p><p><strong>Methods: </strong>Semi-structured qualitative interviews were conducted with BSMM+ in Texas (n=27) to explore perceived barriers and facilitators of sustained care engagement. Interviews lasted 60 minutes on average, were transcribed, coded, and analyzed using applied thematic analysis.</p><p><strong>Findings: </strong>Participants described how important having relationships with engaged and supportive HIV care and service providers is to sustained engagement in care and positive HIV clinical outcomes. Supportive providers were characterized as non-judgmental, meeting patients' needs, and making patients feel \"seen\". Less supportive providers were described as making their patients \"feel like a number\" and having lack of follow through on proposed support and resources. Supportive providers were associated with increased care engagement of their patients while less supportive providers often led to patients switching providers, losing touch with services, and getting off track with their care.</p><p><strong>Discussion: </strong>We found that among BSMM+ an important facilitator of sustained care engagement was having positive, affirming, and knowledgeable healthcare providers, while negative and dismissive experiences with providers was a notable barrier to care engagement. This work highlights the need for a scale up of comprehensive, ongoing trainings in patient-centered and person-first communication for providers. Further, manageable provider caseloads can facilitate more thorough patient interactions where tailored HIV care and education can be provided in a safe and non-judgmental environment.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"1641-1650"},"PeriodicalIF":2.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11313489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141917336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Relationship Between Psychological Constructs and Decision-Making Preferences in Psychiatric Outpatients. 探索精神病门诊患者的心理结构与决策偏好之间的关系。
IF 2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.2147/PPA.S469579
Carlos De Las Cuevas, Omaira Benadero

Objective: This study aimed to elucidate the relationships among health locus of control, psychological reactance, attitudes toward psychiatric treatment, and patient decision-making preferences within a psychiatric outpatient population.

Methods: A total of 200 consecutive psychiatric outpatients from a community mental health center in Tenerife, Spain, were approached for participation between September 2023 and March 2024. Of these, 151 patients consented to participate in this cross-sectional study. Participants were selected based on their willingness to participate and were provided with informed consent forms. Data were collected using the Patient's Health Belief Questionnaire on Psychiatric Treatment (PHBQPT) and the Control Preferences Scale (CPS). The PHBQPT evaluates health beliefs impacting adherence to psychiatric treatment, while the CPS assesses the preferred level of involvement in medical decision-making. Sociodemographic data were also collected to contextualize the findings.

Results: Significant correlations were found between patients' control preferences and their attitudes towards medication, compliance with psychiatric advice, and perceptions of treatment control. A collaborative control preference was notably associated with positive attitudes toward medication and trust in the psychiatrist. These findings suggest that tailored treatment approaches prioritizing patient involvement could enhance adherence and outcomes.

Conclusion:  The study underscores the importance of considering psychological constructs in psychiatric care to foster a holistic, patient-centered approach. Recognizing and integrating patients' control preferences, attitudes towards medication, and psychological reactance can improve the therapeutic relationship and treatment adherence. Future research should explore longitudinal and interventional studies to further understand the impact of aligning treatment approaches with patient preferences and psychological profiles.

研究目的本研究旨在阐明精神病门诊患者的健康控制点、心理反应、对精神病治疗的态度以及患者决策偏好之间的关系:在 2023 年 9 月至 2024 年 3 月期间,西班牙特内里费岛一家社区精神健康中心共接触了 200 名连续的精神病门诊患者。其中,151 名患者同意参加这项横断面研究。研究人员根据患者的参与意愿对其进行筛选,并向其提供知情同意书。研究人员使用患者精神治疗健康信念问卷(PHBQPT)和控制偏好量表(CPS)收集数据。PHBQPT评估的是对坚持精神病治疗有影响的健康信念,而CPS评估的是参与医疗决策的偏好程度。此外,还收集了社会人口学数据,以便对研究结果进行背景分析:结果:研究发现,患者的控制偏好与他们对药物治疗的态度、对精神科建议的依从性以及对治疗控制的看法之间存在明显的相关性。合作控制偏好与对药物治疗的积极态度和对精神科医生的信任明显相关。这些研究结果表明,优先考虑患者参与的定制治疗方法可以提高患者的依从性和治疗效果: 这项研究强调了在精神科治疗中考虑心理因素对促进以患者为中心的整体治疗方法的重要性。认识并整合患者的控制偏好、对药物的态度以及心理反应,可以改善治疗关系和治疗依从性。未来的研究应探索纵向和干预性研究,以进一步了解根据患者偏好和心理特征调整治疗方法的影响。
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引用次数: 0
Influential Factors for Self-Management Among Patients with Diabetic Retinopathy: A Structural Equation Model Analysis 糖尿病视网膜病变患者自我管理的影响因素:结构方程模型分析
IF 2.2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-02 DOI: 10.2147/ppa.s456947
Rina Sa, Jingjing Zhang, Haiyang Xu
Purpose: To investigate the influencing factors of self-management of diabetic retinopathy (DR) by constructing a structural equation model (SEM) to analyze the relationships among self-management behavior, perceived social support, and trait coping style as well as to determine the influencing path in order to provide a theoretical reference for exploring a multipath health management model that can be used to improve the quality of life of DR patients.
Patients and Methods: A total of 388 patients with DR were enrolled in this cross-sectional study conducted from January 2020 to January 2023. All subjects completed a general questionnaire and were assessed by the Self-management Scale for Patients with Diabetic Retinopathy, the Perceived Social Support Scale, and the Trait Coping Style Scale. Structural equation modeling was employed to examine the relationship between self-management and its influencing factors. The bootstrap method was used to examine the path relationships among self-management, perceived social support, and trait coping styles in DR patients.
Results: A total of 346 valid questionnaires were collected in this study, with a response rate of 89% (346/388). The average score of self-management of DR patients was 69.50± 18.32, and it was significantly positively correlated with perceived social support and positive coping (r=0.624, r=0.578, both P< 0.01). The total effect of perceived social support on DR self-management was 1.439, with a direct effect of 1.056 and an indirect effect of 0.384. Positive coping played a mediating role in perceived social support and self-management.
Conclusion: The self-management of DR was at an intermediate level. Perceived social support and trait coping styles were important influencing factors for self-management behavior in DR patients. Therefore, improving perceived social support and trait coping styles can promote the self-management behavior of DR patients, reduce their psychological burden, and improve their compliance and quality of life.

Keywords: diabetic retinopathy, self-management, social support, coping style, structural equation model
目的:通过构建结构方程模型(SEM),分析糖尿病视网膜病变(DR)患者自我管理行为、感知社会支持和特质应对方式之间的关系,并确定影响路径,探讨糖尿病视网膜病变(DR)患者自我管理的影响因素,为探索可用于提高DR患者生活质量的多路径健康管理模式提供理论参考:这项横断面研究于 2020 年 1 月至 2023 年 1 月进行,共招募了 388 名 DR 患者。所有受试者都填写了一份普通问卷,并接受了糖尿病视网膜病变患者自我管理量表、感知社会支持量表和特质应对方式量表的评估。采用结构方程模型研究自我管理与其影响因素之间的关系。采用引导法检验 DR 患者自我管理、感知社会支持和特质应对方式之间的路径关系:本研究共收集了 346 份有效问卷,回收率为 89%(346/388)。DR患者自我管理的平均得分(69.50±18.32)分,与感知到的社会支持和积极应对呈显著正相关(r=0.624,r=0.578,P<均为0.01)。感知到的社会支持对 DR 自我管理的总效应为 1.439,其中直接效应为 1.056,间接效应为 0.384。积极应对在感知到的社会支持和自我管理中起到了中介作用:结论:DR 的自我管理处于中等水平。感知到的社会支持和特质应对方式是 DR 患者自我管理行为的重要影响因素。因此,改善感知社会支持和特质应对方式可促进 DR 患者的自我管理行为,减轻其心理负担,提高其依从性和生活质量。
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引用次数: 0
Post-Intervention Acceptability of a Multicomponent Intervention for Hypertension Management in Primary Care Clinics by Health Care Providers and Patients: A Qualitative Study of a Cluster RCT in Singapore 医护人员和患者对初级保健诊所高血压管理多成分干预措施的干预后接受度:新加坡一项分组 RCT 的定性研究
IF 2.2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.2147/ppa.s469855
Tazeen H Jafar, Ngiap Chuan Tan, Rupesh M Shirore, Chandrika Ramakrishnan, Sungwon Yoon, Christina Chen, Amudha Aravindhan
Background: Hypertension is a major public health challenge, globally. Recently, we reported findings from cluster randomized trial in 8 primary care clinics in Singapore and showed that a multicomponent “SingHypertension” intervention comprising 1) motivational conversation by trained nurses, 2) telephone-based follow-ups, 3) standardized algorithm with single-pill combination (SPC) antihypertensive medications, and 4) subsidy on SPC antihypertensive drugs was effective on improving BP control. This paper presents the acceptability of SingHypertension multicomponent intervention among the key stakeholders.
Methods: We conducted post-implementation interviews of 38 stakeholders, including 18 patients and 20 healthcare providers (HCPs) in 4 primary care clinics randomized to the multicomponent “SingHypertension” intervention in Singapore. We used Theoretical Framework for Acceptability (TFA) framework with a focus on affective attitude, burden, ethicality, intervention coherence, opportunity cost, perceived effectiveness and self-efficacy to assess stakeholders’ acceptability of the intervention.
Results: SingHypertension multicomponent intervention had high perceived effectiveness and a good fit with the value system and ethics of patients and HCPs. Physicians appreciated the guidance from standardized training in hypertension management. Although workload was increased, the nurses felt rewarded for their positive interactions with the patients during motivational conversation sessions and the telephone follow-ups. Most patients reported high self-efficacy levels, improved lifestyles, and adherence to antihypertensive medications. The limited choice of SPC medication, lack of subsidy beyond the trial duration, and shortage of nurses were significant challenges to wide-scale implementation. All HCPs and patients supported scaling up the intervention across primary care clinics.
Conclusion: SingHypertension multicomponent intervention is acceptable to the key stakeholders in Singapore. Taken together with the effectiveness of the intervention, our findings make a compelling case for scaling-up SingHypertension in primary care clinics in Singapore and possibly other countries with similar healthcare infrastructure.

背景:高血压是全球面临的一项重大公共卫生挑战。最近,我们报告了在新加坡 8 家初级保健诊所进行的分组随机试验的结果,结果表明由以下几方面组成的多成分 "SingHypertension "干预措施能有效改善血压控制:1)由受过培训的护士进行激励性谈话;2)基于电话的随访;3)标准化算法与单药组合(SPC)降压药物;4)SPC 降压药物补贴。本文介绍了主要利益相关者对 SingHypertension 多成分干预措施的接受程度:我们对新加坡 4 家随机接受多组分 "SingHypertension "干预措施的初级保健诊所的 38 名利益相关者进行了实施后访谈,其中包括 18 名患者和 20 名医疗保健提供者(HCPs)。我们采用了可接受性理论框架(TFA),重点关注情感态度、负担、道德性、干预一致性、机会成本、感知有效性和自我效能,以评估利益相关者对干预的可接受性:结果:SingHypertension 多组分干预措施具有较高的可感知有效性,并且与患者和保健医生的价值体系和道德规范十分契合。医生对高血压管理标准化培训的指导表示赞赏。虽然工作量增加了,但护士们在激励谈话环节和电话随访中与患者积极互动,感到很有收获。大多数患者表示自我效能水平高,生活方式得到改善,并坚持服用降压药。SPC 药物选择有限、试验期结束后缺乏补贴以及护士短缺是大范围实施的重大挑战。所有医护人员和患者都支持在初级保健诊所推广该干预措施:结论:SingHypertension 多成分干预措施为新加坡的主要利益相关者所接受。结合干预措施的有效性,我们的研究结果为在新加坡以及其他拥有类似医疗基础设施的国家的初级保健诊所推广 SingHypertension 提供了令人信服的理由。
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引用次数: 0
Video Education and Behavior Contract to Improve Outcomes After Renal Transplantation (VECTOR): A Randomized Controlled Trial 改善肾移植术后疗效的视频教育和行为契约 (VECTOR):随机对照试验
IF 2.2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-31 DOI: 10.2147/ppa.s467142
Holly Mansell, Nicola Rosaasen, Jenny Wichart, Patricia West-Thielke, David Blackburn, Juxin Liu, Rahul Mainra, Ahmed Shoker, Brianna Groot, Kevin Wen, Anita Wong, Bita Bateni, Cindy Luo, Paraag Trivedi
Abstract: Sub-optimal adherence to immunosuppressant medications reduces graft survival for kidney transplant recipients and adherence-enhancing interventions are resource and time intensive. We performed a multi-center randomized controlled trial to investigate the impact of an electronically delivered intervention on adherence. Of 203 adult kidney transplant recipients who received a de novo kidney transplant n = 173 agreed to participate (intent-to-treat population) and were randomized to the intervention (video education plus behavior contract n = 91) or the control (standard education, n = 82). No significant differences were found between the groups for medication adherence measured by the Basel Assessment of Adherence to Immunosuppressive Medications Scale, intrapatient variability in tacrolimus levels, time in therapeutic range for any immunosuppressant, knowledge, self-efficacy, QOL, or hospitalizations. Among a subgroup of 64 participants randomized to the intervention group who completed a post-intervention questionnaire, two-thirds (67%, n = 43) reported watching at least 80% of the videos and 58% (n = 37) completed the electronic goal setting exercise and adherence contract. An autonomous goal setting exercise and electronic behavioural contract added to standard of care did not improve any outcomes. Our findings reiterate that nonadherence in transplantation is a difficult multifactorial problem that simple solutions will not solve. Trial registration number NCT03540121.

Keywords: kidney transplant, solid organ transplant, medication adherence, immunosuppression
摘要:免疫抑制药物的依从性不达标会降低肾移植受者的移植物存活率,而提高依从性的干预措施需要耗费大量的资源和时间。我们进行了一项多中心随机对照试验,研究电子干预对依从性的影响。在 203 名接受了新肾移植的成人肾移植受者中,有 173 人同意参与(意向治疗人群),他们被随机分配到干预组(视频教育加行为合同,91 人)或对照组(标准教育,82 人)。通过巴塞尔免疫抑制剂用药依从性评估量表(Basel Assessment of Adherence to Immunosuppressive Medications Scale)测量的用药依从性、患者间他克莫司水平的变异性、任何免疫抑制剂在治疗范围内的时间、知识、自我效能、QOL或住院情况在两组间没有发现明显差异。在随机加入干预组并完成干预后问卷调查的 64 名参与者中,三分之二(67%,n = 43)的人表示至少观看了 80% 的视频,58%(n = 37)的人完成了电子目标设定练习和坚持治疗合同。在标准护理的基础上增加自主目标设定练习和电子行为契约并未改善任何结果。我们的研究结果再次表明,移植中的不依从性是一个棘手的多因素问题,简单的解决方案无法解决这一问题。试验注册号:NCT03540121.关键词:肾移植、实体器官移植、用药依从性、免疫抑制
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引用次数: 0
Physician and Patient Preferences for Treatment of Anemia Associated with Chronic Kidney Disease in Japan: A Survey Including Best-Worst Scaling 日本医生和患者对慢性肾病相关贫血治疗的偏好:包括最佳-最差评分在内的一项调查
IF 2.2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-31 DOI: 10.2147/ppa.s450464
Sari Mishina, Yuichiro Ito, Takumi Lee, Toshiaki Murofushi, Yoshiyuki Uetake, Tadao Akizawa
Background: Several treatment options are available for anemia associated with chronic kidney disease (CKD); however, there remains a lack of awareness of physician and patient preferences regarding these treatments. We aimed to explore physicians’ and patients’ perceptions and preferences regarding the management of anemia of CKD in Japan.
Methods: A web-based survey, including best-worst scaling (BWS), was conducted with physicians who had treated ≥ 1 patient with anemia of CKD in the preceding year, and with patients with CKD who self-reported a clinical diagnosis of anemia of CKD or low hemoglobin levels. A three-step approach was used comprising cognitive interviews, a pilot survey, and a main survey. The BWS survey results were analyzed using multinomial logit and hierarchical Bayesian models.
Results: The survey was completed by 906 participants: 103 patients (average age 60.6 years; 77.7% male) and 803 physicians (166 nephrologists, 214 cardiologists, 137 diabetologists, and 286 general internists). Almost all (96.0%) physicians surveyed considered anemia of CKD to be an important condition to treat. Hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitors had the highest treatment satisfaction among physicians, whereas patients had the highest satisfaction with both erythropoietin-stimulating agent therapy and HIF-PH inhibitors. Approximately one-third (35.9%) of patients surveyed indicated that they were receiving treatment. When comparing the relative importance of attributes and levels, physicians favored efficacy (particularly improvement in hemoglobin levels), whereas patients favored safety (particularly a lower rate of severe adverse events).
Conclusion: Although a majority of physicians consider treatment of CKD-related anemia important, differences in the perceptions and usage of medications exist between medical specialties. Preferences for the management of anemia of CKD vary between physicians and patients; therefore, patient involvement in treatment decisions may help optimize outcomes.

背景:慢性肾脏病(CKD)相关贫血症有多种治疗方案可供选择;然而,医生和患者对这些治疗方法的偏好仍然缺乏了解。我们旨在探讨日本医生和患者对 CKD 贫血治疗的看法和偏好:方法:我们对上一年治疗过≥ 1 名 CKD 贫血患者的医生,以及自述临床诊断为 CKD 贫血或血红蛋白水平低的 CKD 患者进行了一项网络调查,其中包括最佳-最差评分法 (BWS)。调查分三步进行,包括认知访谈、试点调查和主要调查。采用多叉 logit 模型和分层贝叶斯模型对 BWS 调查结果进行了分析:共有 906 名参与者完成了调查:103 名患者(平均年龄 60.6 岁;77.7% 为男性)和 803 名医生(166 名肾病专家、214 名心脏病专家、137 名糖尿病专家和 286 名普通内科医生)。几乎所有(96.0%)接受调查的医生都认为慢性肾脏病贫血是一种需要治疗的重要疾病。医生对缺氧诱导因子脯氨酰羟化酶(HIF-PH)抑制剂的治疗满意度最高,而患者对促红细胞生成素治疗和 HIF-PH 抑制剂的满意度也最高。约三分之一(35.9%)的受访患者表示他们正在接受治疗。在比较属性和水平的相对重要性时,医生倾向于疗效(尤其是血红蛋白水平的改善),而患者则倾向于安全性(尤其是严重不良反应发生率较低):结论:尽管大多数医生认为治疗与慢性肾脏病相关的贫血很重要,但不同医学专业对药物的认识和使用存在差异。因此,让患者参与治疗决策有助于优化治疗效果。
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引用次数: 0
Awareness of Breast Cancer Risk Factors in Women with vs. Without High Breast Density 乳房密度高与否的女性对乳腺癌风险因素的认识
IF 2.2 3区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-31 DOI: 10.2147/ppa.s466992
Jan Endrikat, Gilda Schmidt, Bhagyashree Oak, Viplav Shukla, Prakirti Nangia, Nicolas Schleyer, John Crocker, Ruud Pijnapppel
Purpose: Women with high breast density (HBD) carry an increased risk for breast cancer (BC). The aim of the study was to provide data on awareness and knowledge gaps among women with vs w/o HBD about BC risk factors (BCRFs), which is the basis for effective communication about screening.
Patients and Methods: This was a web-based survey of 3000 women aged ≥ 30 and ≤ 70 from six countries. It comprised of 45 questions. T-tests and chi-square tests with False Discovery Rate adjustments were conducted as applicable, with significant differences reported at α=0.05.
Results: Three-thousand women were included in the analysis, 733 (24.4%) had HBD. Overall, 39% of women were familiar with the concept of HBD in the context of BC. Thirty-one percent of women were aware of HBD as BCRF and for 24% of women HBD was personally applicable. A significantly higher proportion of women with HBD were aware of almost all BCRFs compared to women w/o HBD (p ≤ 0.05). Similarly, a significantly higher proportion of women with HBD have undergone screening procedures compared to women w/o HBD (p ≤ 0.05). Women with HBD were significantly better aware of basic facts about BC (p ≤ 0.05). A total of 1617 women underwent mammography, 904 ultrasound and 150 MRI during their last screening. The most relevant source of information about BC was the health care professional, as reported by 63% of women.
Conclusion: Overall 39% of women were familiar with HBD as BCRF. Lack of BCRF awareness may contribute to delayed screenings, missed opportunities for early detection, and potentially poorer outcomes for individuals with dense breast tissue. Thus, this information should be communicated more widely.

Keywords: breast cancer risk factors, dense breast, screening, imaging modalities, sources of information
目的:高乳腺密度(HBD)女性罹患乳腺癌(BC)的风险更高。该研究旨在提供数据,说明患有与未患有高乳腺密度的女性对乳腺癌风险因素(BCRFs)的认识和知识差距,这是进行有效筛查沟通的基础:这是一项基于网络的调查,调查对象是来自六个国家的 3000 名年龄≥ 30 岁和≤ 70 岁的女性。调查包括 45 个问题。根据情况进行了 T 检验和带误差发现率调整的卡方检验,在 α=0.05 时报告显著差异:共有三千名妇女参与了分析,其中 733 人(24.4%)患有 HBD。总体而言,39% 的妇女熟悉 BC 中的 HBD 概念。31%的女性知道 HBD 是 BCRF,24%的女性认为 HBD 对其个人适用。与未患有 HBD 的妇女相比,患有 HBD 的妇女了解几乎所有 BCRF 的比例明显更高(p ≤ 0.05)。同样,与未患乙肝的妇女相比,患乙肝的妇女接受筛查程序的比例明显更高(p ≤ 0.05)。患有 HBD 的妇女对 BC 基本知识的了解程度明显更高(p ≤ 0.05)。在最近一次筛查中,共有 1617 名妇女接受了乳房 X 线照相术,904 名妇女接受了超声波检查,150 名妇女接受了核磁共振成像检查。63%的妇女表示,关于乳腺癌的最相关信息来源是医护人员:结论:总体而言,39% 的妇女熟悉作为 BCRF 的 HBD。缺乏对 BCRF 的认识可能会导致筛查延迟、错失早期发现的机会,并可能使致密乳腺组织患者的治疗效果更差。因此,应更广泛地传播这一信息。关键词:乳腺癌风险因素、致密乳房、筛查、成像模式、信息来源
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引用次数: 0
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Patient preference and adherence
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