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Discussion: Perioperative Vitamin D Insufficiency Impacts Postoperative Outcomes in Abdominally Based Breast Reconstruction. 讨论:围手术期维生素D不足影响腹部乳房再造术的术后结果。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2026-03-25 DOI: 10.1097/PRS.0000000000012661
Min-Jeong Cho
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引用次数: 0
Reply: Use of Text-to-Image Artificial Intelligence Model in Preoperative Counseling for Lip-Lift Procedures. 回复:文本-图像人工智能模型在唇部拉皮手术术前咨询中的应用。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2026-03-25 DOI: 10.1097/PRS.0000000000012500
Ryan S Huang, Michael Balas, Flora Yan, Allan E Wulc
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引用次数: 0
The Impact of Vascularized Lymph Node Transfer in Reducing the Rate of Cellulitis in Breast Cancer-Related Lymphedema. 血管化淋巴结转移对降低乳腺癌相关淋巴水肿患者蜂窝织炎发生率的影响
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2025-08-26 DOI: 10.1097/PRS.0000000000012412
Alejandro Perez, Mark V Schaverien, Monica George-Palop, Edward I Chang, Carlos H Barcenas, George M Viola

Background: Poorly managed breast cancer-related lymphedema may lead to recurrent cellulitis. Advances in the management of lymphedema have evolved beyond conservative decongestive therapy to include vascularized lymph node transfer (VLNT). In this article, the authors analyze the impact of VLNT in the reduction of upper extremity cellulitis in breast cancer survivors.

Methods: The authors reviewed all patients at their institution who had breast cancer, underwent mastectomy, experienced upper extremity lymphedema, and proceeded with VLNT from 2017 to 2021. Patients were included if they had 1 or more episodes of cellulitis within the year before VLNT and were followed up for at least 12 months.

Results: The authors included 66 patients who fulfilled their strict inclusion criteria, with a median age of 57 years (interquartile range, 23 to 76 years). All patients were female, and most were White (88%), with a mean ± SD body mass index of 29.4 ± 6.7 kg/m 2 . Many presented with invasive ductal carcinoma (82%), had axillary lymph node dissection (98%), and received chemotherapy (94%) and radiation therapy (86%). VLNT was performed at a median of 92 months after mastectomy (interquartile range, 32 to 156 months). Overall, 58 (88%) patients remained infection-free with an infection rate decrease from an average of 2.27 before the index VLNT to 0.17 ( P < 0.0001) after VLNT.

Conclusions: VLNT is associated with significantly decreased cellulitis rates. It should be considered as part of the treatment for infectious diseases of recurrent upper extremity cellulitis caused by breast cancer-related lymphedema with no adequate clinical improvement from conservative management alone.

背景:乳腺癌相关淋巴水肿(BCRL)管理不善可能导致蜂窝织炎复发。淋巴水肿的治疗进展已经从保守的减充血疗法发展到包括血管化淋巴结转移(VLNT)。在此,我们分析了VLNT在减少乳腺癌幸存者上肢蜂窝织炎方面的影响。方法:我们回顾了2017年至2021年我院所有患有乳腺癌、接受乳房切除术、上肢淋巴水肿并进行了VLNT的患者。如果患者在VLNT前一年内有1次或1次以上蜂窝织炎发作,并随访至少12个月,则纳入研究。结果:我们纳入了66例符合严格纳入标准的患者,中位年龄为57岁(IQR, 23-76岁)。所有患者均为女性,白人居多(88%),平均(±SD)体重指数为29.4±6.7 kg/m2。许多患者表现为浸润性导管癌(82%),腋窝淋巴结清扫(98%),接受化疗(94%)和放疗(86%)。VLNT在乳房切除术后中位92个月(IQR, 32-156个月)进行。总体而言,58例(88%)患者保持无感染,感染率从指数VLNT前的平均2.27下降到VLNT后的0.17 (P < 0.0001)。结论:VLNT可显著降低蜂窝织炎的发生率,对于单纯保守治疗无明显临床改善的BCRL引起的复发性上肢蜂窝织炎,应考虑将其纳入感染性疾病治疗方案。
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引用次数: 0
Temporal Modified Orbicularis Repositioning: Going beyond the Limits of Temporal Lifting. 颞部移位(改良轮匝肌复位):超越颞部提升。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2025-08-19 DOI: 10.1097/PRS.0000000000012391
Stefano Cotrufo
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引用次数: 0
Impact of Palatoplasty on Middle-Ear Effusion in Children with Cleft Lip and Palate. 腭裂患儿腭裂成形术前后中耳积液相关因素的回顾性研究。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2025-08-26 DOI: 10.1097/PRS.0000000000012413
Edward Hung-Lun Chu, Te-Wei Cheng, Philip Kuo-Ting Chen, Yen-Chun Chen, Hann-Ziong Yueh, Shih-Chun Lu, Hua-Kai Chi, Chen-Yeh Yu, Che-Hsuan Lin

Background: Previous studies have primarily evaluated postoperative middle-ear outcomes following palatoplasty and ventilation tube insertion (VTI), with a focus on patient age and cleft severity. However, few have investigated the influence of cleft sidedness and variations in Furlow-based palatoplasty techniques. This study aimed to assess the presence of otitis media with effusion (OME) before and after palatoplasty, with or without VTI, and to identify factors associated with OME, including baseline patient characteristics, cleft sidedness, and surgical approach.

Methods: The authors retrospectively analyzed 86 children with cleft palate or cleft lip and palate who underwent palatoplasty at their hospital from October of 2017 to December of 2021, with at least 2 years of follow-up evaluating middle-ear outcomes.

Results: Age at palatoplasty date, sex, congenital anomalies, and cleft severity were not significantly associated with preoperative OME. Complete clefts showed a higher OME incidence than incomplete cleft palate in univariable analysis, but not in multivariable analysis. The use rate of Furlow palatoplasty combined with hard palate repair increased with increasing cleft severity. Neither the choice of palatoplasty technique nor cleft sidedness was significantly associated with the presence of OME before palatoplasty or with the development of OME after palatoplasty. Postoperative OME rates were similar between children with OME undergoing VTI and those without OME treated by palatoplasty alone.

Conclusions: Cleft sidedness and surgical technique did not influence OME before or after palatoplasty. Ventilation tube insertion is beneficial for patients with OME but may be unnecessary in those without prior effusion.

背景:先前的研究主要评估腭成形术和通气管插入(VTI)后的中耳术后结果,重点关注患者的年龄和唇裂严重程度。然而,很少有人调查腭裂的影响和在furlow基础上的腭成形术的变化。本研究旨在评估腭裂成形术前后,伴或不伴VTI的中耳炎伴积液(OME)的存在,并确定与OME相关的因素,包括基线患者特征、侧裂和手术入路。方法:回顾性分析2017年10月至2021年12月在我院行腭裂成形术的86例腭裂或唇腭裂患儿,随访至少2年,评估中耳预后。结果:腭裂成形术时的年龄、性别、先天性异常和腭裂严重程度与术前OME无显著相关。单因素分析显示完全性腭裂的OME发生率高于完全性腭裂,多因素分析显示OME发生率低于完全性腭裂。随着腭裂严重程度的增加,Furlow腭成形术联合硬腭修复术的使用率增加。腭成形术的选择和腭裂与腭成形术前的OME存在或腭成形术后OME的发展均无显著相关性。术后OME患儿行VTI和单纯腭裂治疗无OME患儿的OME率相似。结论:腭裂程度和手术技术对腭裂成形术前后的OME无明显影响。通气管的插入对OME患者是有益的,但对于没有积液的患者可能是不必要的。
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引用次数: 0
Breast Codes: Triple-Plane Autologous Fat Grafting in Mastopexies and Reduction Mammaplasties without Implants. 乳房代码:乳房切除术和乳房缩小成形术中的三平面自体脂肪移植术。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2025-08-13 DOI: 10.1097/PRS.0000000000012385
Ricardo T Nóra, Lydia M Ferreira

Several techniques for performing mastopexy and reduction mammaplasty have been reported; however, none has effectively maintained breast and upper pole projection. Silicone implants address these limitations but are associated with higher risks than nonimplant surgical procedures. Growing concerns include the risk of anaplastic large cell lymphoma and adjuvant-induced autoimmune syndrome. In addition, some women desire volume enhancement without implants. Autologous fat grafting is increasingly used for aesthetic breast augmentation and reconstruction. However, few studies have explored its combined use in muscle and breast planes during reduction mammaplasty and mastopexy. No study has yet standardized fat grafting across submuscular, intramuscular, and subcutaneous planes. This study is innovative in systematizing the fat grafting technique and standardizing its simultaneous application to the submuscular, intramuscular, and subcutaneous planes during mastopexy and reduction mammaplasty. It also identifies specific grafting zones for upper pole projection.

总结:已经报道了几种进行乳房切除术和缩乳术的技术;然而,没有人有效地保持乳房和上极突出。硅胶植入物解决了这些局限性,但与非植入物手术相比风险更高。越来越多的关注包括间变性大细胞淋巴瘤和佐剂诱导的自身免疫综合征的风险。此外,一些女性希望在没有植入物的情况下增大体积。自体脂肪移植越来越多地用于美容隆胸和乳房重建。然而,很少有研究探讨其在缩乳和乳房固定术中在肌肉和乳房平面的联合应用。目前还没有研究对肌肉下、肌肉内和皮下的脂肪移植进行标准化。本研究创新性地将脂肪移植技术系统化,并规范其在乳房切除术和缩乳术中同时应用于肌下、肌内和皮下平面。它还确定了上极投影的特定嫁接区域。
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引用次数: 0
Prophylactic Muscle Flap Closure after Spinal Fusion Improves Outcomes and Reduces Health Care Costs. “脊柱融合术后预防性肌瓣关闭可改善预后并降低医疗费用”。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2025-09-16 DOI: 10.1097/PRS.0000000000012448
Grant G Black, Makayla Kochheiser, Nancy Qin, Matthew A Wright, Michael S Virk, Anjile An, Ali Jalali, David M Otterburn

Background: Spinal degeneration and deformities affect more than 27% of US adults, and $14.1 billion is spent annually on spinal fusion to address these pathologies. Wound closure using local muscle flaps has been associated with reduced complication rates, including infection and reoperation. The high prevalence of degenerative deformities and health care expenditures highlight the need for resource utilization studies to inform decision-makers on best operative practices.

Methods: A retrospective review was performed on adult patients who underwent posterior spinal fusion for degenerative or deformity indications at the authors' institution between 2019 and 2022. Patients were stratified by the prophylactic use of muscle flap closure, and outcomes were compared between groups. Costs were applied to consumed resources, and univariate and multivariable regression analyses were performed to measure the impact of muscle flaps on overall costs.

Results: Of 520 included patients, 240 received muscle flap closures. These patients had significantly fewer readmissions (odds ratio [OR], 0.49 [95% CI, 0.29, 0.84]), reoperations (OR, 0.49 [95% CI, 0.26, 0.89]), and hardware failures (OR, 0.09 [95% CI, 0.00, 0.45]), but greater odds of seroma (OR, 5.22 [95% CI, 2.12, 15.7]). They also had shorter hospital stays (5.4 versus 6.5 days [ P = 0.033]), but operative time did not vary by closure type. Multivariable regression revealed that muscle flap closure was associated with a $7152 reduction in overall costs per patient ( P < 0.03).

Conclusions: Muscle flap closure correlates with reduced complication rates and decreased overall costs per patient. These findings support the use of prophylactic muscle flap closure from safety and health economics perspectives.

背景:超过27%的美国成年人患有脊柱退变和畸形,每年花费141亿美元用于脊柱融合术以治疗这些疾病。使用局部肌肉瓣闭合伤口可以降低并发症发生率,包括感染和再手术。退行性畸形的高流行率和医疗保健支出突出表明需要进行资源利用研究,以便为决策者提供最佳手术做法方面的信息。方法:对2019年至2022年在我院因退行性或畸形指征接受后路脊柱融合术的成年患者进行回顾性分析。通过预防性使用肌瓣关闭对患者进行分层,并比较两组之间的结果。将成本应用于消耗的资源,并进行单变量和多变量回归来衡量肌肉皮瓣对总成本的影响。结果:纳入520例患者;240例接受肌瓣闭合。这些患者的再入院率(OR 0.49, 95% CI: 0.29, 0.84)、再手术率(OR 0.49, 95% CI: 0.26, 0.89)和硬件故障率(OR 0.09, 95% CI: 0.00, 0.45)显著降低,但血肿发生率更高(OR 5.22, 95% CI: 2.12, 15.7)。他们的住院时间也较短(5.4天对6.5天;p=0.033),但手术时间没有因闭合类型而变化。多变量回归显示,肌肉瓣关闭与每位患者总成本降低7152美元相关(结论:肌肉瓣关闭与并发症发生率降低相关,同时导致每位患者总成本降低)。这些发现从安全和健康经济学的角度支持预防性肌瓣关闭的使用。
{"title":"Prophylactic Muscle Flap Closure after Spinal Fusion Improves Outcomes and Reduces Health Care Costs.","authors":"Grant G Black, Makayla Kochheiser, Nancy Qin, Matthew A Wright, Michael S Virk, Anjile An, Ali Jalali, David M Otterburn","doi":"10.1097/PRS.0000000000012448","DOIUrl":"10.1097/PRS.0000000000012448","url":null,"abstract":"<p><strong>Background: </strong>Spinal degeneration and deformities affect more than 27% of US adults, and $14.1 billion is spent annually on spinal fusion to address these pathologies. Wound closure using local muscle flaps has been associated with reduced complication rates, including infection and reoperation. The high prevalence of degenerative deformities and health care expenditures highlight the need for resource utilization studies to inform decision-makers on best operative practices.</p><p><strong>Methods: </strong>A retrospective review was performed on adult patients who underwent posterior spinal fusion for degenerative or deformity indications at the authors' institution between 2019 and 2022. Patients were stratified by the prophylactic use of muscle flap closure, and outcomes were compared between groups. Costs were applied to consumed resources, and univariate and multivariable regression analyses were performed to measure the impact of muscle flaps on overall costs.</p><p><strong>Results: </strong>Of 520 included patients, 240 received muscle flap closures. These patients had significantly fewer readmissions (odds ratio [OR], 0.49 [95% CI, 0.29, 0.84]), reoperations (OR, 0.49 [95% CI, 0.26, 0.89]), and hardware failures (OR, 0.09 [95% CI, 0.00, 0.45]), but greater odds of seroma (OR, 5.22 [95% CI, 2.12, 15.7]). They also had shorter hospital stays (5.4 versus 6.5 days [ P = 0.033]), but operative time did not vary by closure type. Multivariable regression revealed that muscle flap closure was associated with a $7152 reduction in overall costs per patient ( P < 0.03).</p><p><strong>Conclusions: </strong>Muscle flap closure correlates with reduced complication rates and decreased overall costs per patient. These findings support the use of prophylactic muscle flap closure from safety and health economics perspectives.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"581e-590e"},"PeriodicalIF":3.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demystifying Deep Layer Face-Lift Techniques: A Systematic Review of Superficial Musculoaponeurotic System Techniques. “揭开深层拉皮技术的神秘面纱:内侧基SMAS技术的系统回顾”。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2025-10-16 DOI: 10.1097/PRS.0000000000012526
Kelly P Schultz, Rami Sherif, Nishant Ganesh Kumar, James M Stuzin, Rod J Rohrich

Background: Facial aging is a multifactorial process that results from deflation and descent of facial soft tissue. Modern deep layer face-lift techniques aim to restore a youthful facial shape by using the superficial musculoaponeurotic system (SMAS) to reposition descended facial fat into areas of deflation within the lateral cheek and malar eminence. Although there are many advocates of various SMAS techniques and numerous descriptions of methods to manipulate and fixate repositioned facial fat, there is no consensus in the literature as to a "best" SMAS technique. The authors' investigation aimed to determine whether there should be a consensus on the preferred method of SMAS manipulation in terms of improving contour in the aging face.

Methods: A systematic review was performed to investigate the current body of literature on SMAS face-lift techniques. Careful review of operative technique was performed, and techniques were classified as medially or laterally based, depending on the extent of sub-SMAS dissection. Analysis of aesthetic outcomes and complications was performed to determine the superiority of one technique over another in achieving a youthful facial contour.

Results: A total of 17 articles were selected for review that clearly described operative technique and reported aesthetic outcomes. Patient satisfaction and improvement in overall facial contour was noted across studies.

Conclusions: Various SMAS techniques can provide excellent aesthetic outcomes; however, medially based "deep plane" techniques, which carry dissection medial to the stout retaining ligaments, have not been shown to provide significant improvement in the appearance of the midface or improved longevity of results.

背景:面部衰老是一个多因素的过程,是由面部软组织收缩和下降引起的。现代深层拉皮技术的目的是通过利用SMAS将下降的面部脂肪重新定位到外侧脸颊和颧隆起的收缩区域,以恢复年轻的面部形状。虽然有许多人提倡各种SMAS技术,并且对操纵和固定重新定位的面部脂肪的方法进行了大量描述,但关于“最佳”SMAS技术,文献中没有达成共识。我们的研究是基于确定是否所述的各种描述技术的优势值得在SMAS操作的首选方法上达成共识,以改善老化面部的轮廓。方法:系统地回顾了目前关于SMAS整容技术的文献。对手术技术进行了仔细的审查,并根据smas下剥离的程度将技术分为内侧或外侧。为了确定一种技术在实现年轻面部轮廓方面优于另一种技术,对美学结果和并发症进行了分析。结果:共选择17篇文章进行回顾,这些文章清晰地描述了手术技术和报道的美学结果。所有研究都注意到患者满意度和整体面部轮廓的改善。结论:多种SMAS技术均可获得良好的美学效果;然而,以内侧为基础的“深平面”技术,即在坚固的保留韧带内侧进行剥离,并没有显示出对中面部外观的显着改善或延长结果的寿命。
{"title":"Demystifying Deep Layer Face-Lift Techniques: A Systematic Review of Superficial Musculoaponeurotic System Techniques.","authors":"Kelly P Schultz, Rami Sherif, Nishant Ganesh Kumar, James M Stuzin, Rod J Rohrich","doi":"10.1097/PRS.0000000000012526","DOIUrl":"10.1097/PRS.0000000000012526","url":null,"abstract":"<p><strong>Background: </strong>Facial aging is a multifactorial process that results from deflation and descent of facial soft tissue. Modern deep layer face-lift techniques aim to restore a youthful facial shape by using the superficial musculoaponeurotic system (SMAS) to reposition descended facial fat into areas of deflation within the lateral cheek and malar eminence. Although there are many advocates of various SMAS techniques and numerous descriptions of methods to manipulate and fixate repositioned facial fat, there is no consensus in the literature as to a \"best\" SMAS technique. The authors' investigation aimed to determine whether there should be a consensus on the preferred method of SMAS manipulation in terms of improving contour in the aging face.</p><p><strong>Methods: </strong>A systematic review was performed to investigate the current body of literature on SMAS face-lift techniques. Careful review of operative technique was performed, and techniques were classified as medially or laterally based, depending on the extent of sub-SMAS dissection. Analysis of aesthetic outcomes and complications was performed to determine the superiority of one technique over another in achieving a youthful facial contour.</p><p><strong>Results: </strong>A total of 17 articles were selected for review that clearly described operative technique and reported aesthetic outcomes. Patient satisfaction and improvement in overall facial contour was noted across studies.</p><p><strong>Conclusions: </strong>Various SMAS techniques can provide excellent aesthetic outcomes; however, medially based \"deep plane\" techniques, which carry dissection medial to the stout retaining ligaments, have not been shown to provide significant improvement in the appearance of the midface or improved longevity of results.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"615-620"},"PeriodicalIF":3.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From T to L to I: Risk Factors in Medial Thigh Lifts after Massive Weight Loss-Is Less Sometimes More? “从T到L再到I:大量减肥后大腿内侧提升的危险因素。“少有时多”?
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2025-08-26 DOI: 10.1097/PRS.0000000000012407
Melodi Motamedi, Amro Amr, Raya Isaev, Jenny Ehrmanntraut, Sixtus Allert

Background: Thigh-lift surgery is considered a complication-prone operation, with publications reporting complication rates between 35% and 74%. These studies have not specifically evaluated the effects of each technique on the complication rates. This study presents complication rates for the 3 most common surgical techniques (T, L, and I thigh lifts) and evaluates possible causes in the largest reported cohort of patients with massive weight loss.

Methods: A retrospective cohort study of 750 thigh lifts in 375 patients from 2008 through 2023 was performed. The data collected were collated into the 3 thigh-lift techniques and analyzed according to preoperative risk factors and postoperative complications.

Results: The overall complication rate was the lowest for I thigh lifts (40.3%), followed by T thigh lifts (66.6%) and then L thigh lifts (73.9%). An analysis of major complications revealed rates of 9.5%, 33%, and 39.1%, respectively. Smoking, a body mass index of 30 or above, higher temperatures, and prolonged operative duration were found to increase the risk of complications.

Conclusion: The I incision technique for thigh-lift surgery after massive weight loss has fewer complications, reduces scarring and operating times, and has a low revision rate.

背景:大腿提抬手术被认为是一种容易发生并发症的手术,出版物报道并发症发生率在35%至74%之间。这些研究虽然深入,但并没有具体评估每种技术对并发症发生率的影响。本研究介绍了三种最常见的手术技术(T型、L型和i型大腿提术)的并发症发生率,并评估了大量体重减轻(MWL)患者的可能原因。方法:回顾性队列研究,2008年至2023年,对375例患者进行750例大腿举术。将收集到的数据整理成三种抬腿技术,并根据术前危险因素和术后并发症进行分析。结果:I组总并发症发生率最低(40.3%),T组次之(66.6%),L组次之(73.9%)。主要并发症的发生率分别为9.5%、33%和39.1%。这项研究还表明,吸烟、体重指数30及以上、体温较高和手术时间延长会增加并发症的风险。结论:i型切口技术用于大规模减肥后大腿提腹手术,并发症少,疤痕少,手术次数少,翻修率低。
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引用次数: 0
Pragmatic Clinical Trials in Plastic Surgery. 整形外科的实用临床试验。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-04-01 Epub Date: 2025-08-11 DOI: 10.1097/PRS.0000000000012362
Emily R Geis, Amy S Colwell, Kevin C Chung

The use of pragmatic clinical trials (PCTs) has been increasing within medical and surgical research departments, but has not yet been widely implemented in plastic surgery. PCTs are similar to randomized controlled trials (RCTs) in that they both randomize patients to treatments and follow them prospectively after treatment. However, PCTs are less strict than RCTs in many ways: PCTs have fewer inclusion and exclusion criteria, to facilitate the recruitment of representative samples; use data collected during routine clinical care; and commonly rely on subjective patient-reported outcomes. PCTs offer many advantages over the standard RCT, including greater cost efficiency, larger sample sizes, and faster completion times. Because of these advantages, PCTs offer potential benefits to plastic surgery research efforts, but researchers must make intentional design choices when planning a PCT. Researchers should consider the ethics of their study question and treatment identification, appropriate randomization techniques, reliable plans to mitigate possible bias, and minimal but sufficient follow-up plans.

摘要:实用临床试验在医学和外科研究部门的应用越来越多,但尚未在整形外科中广泛实施。实用临床试验(PCTs)类似于随机对照试验(RCTs),它们都是随机分配患者接受治疗,并在治疗后对患者进行前瞻性随访。然而,实用试验在许多方面不如随机对照试验严格:pct的纳入和排除标准较少,以方便代表性样本的招募,pct在常规临床护理期间收集数据,并且通常依赖于患者主观报告的结果。与标准的随机对照试验相比,实用的临床试验具有许多优势,包括更高的成本效率、更大的样本量和更快的完成时间。由于这些优势,实用试验为整形外科研究工作提供了潜在的好处,但研究人员在计划实用试验时必须做出有意的设计选择。研究人员应考虑其研究问题的伦理性和治疗方法的确定、适当的随机化技术、减轻可能的偏倚的可靠计划以及最少但足够的随访计划。
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引用次数: 0
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Plastic and reconstructive surgery
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