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The Evaluation of Online Medical Consultation Use in Pediatric Out-of-Hospital Cardiac Arrest. 评估在线医疗咨询在小儿院外心脏骤停中的应用。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-11-04 DOI: 10.1080/10903127.2024.2406029
SunHee Chung, Asia Wooten, Matthew Hansen, Matthew Neth, Joshua Lupton

Objectives: Our study details Online medical consultation (OLMC) usage for Pediatric out-of-hospital cardiac arrest (P-OHCA), including proportion of P-OHCA utilizing OLMC, the characteristics of cases using OLMC, the types of information exchanged during OLMC calls, and the outcomes in patients where Emergency Medical Services (EMS) contacted OLMC.

Methods: The study included P-OHCA patients treated by EMS agencies participating in the regional cardiac registry with total catchment population of approximately 1.5 million residents. We reviewed linked calls and EMS charts for P-OHCA cases treated from January 1st, 2018 through December 31st, 2022.

Results: In total, 112 cases from January 2018 to December 2022 were included in the final analysis. Twenty-two out of 112 utilized OLMC with a mean time from 9-1-1 call to OLMC of 28.8 min. The no OLMC group had a significantly higher transport rate than OLMC group as well as higher percentages of ROSC at any time and ROSC upon arrival at the ED. Both survival to admission and survival to discharge were more prevalent in the no OLMC group, while there were no instances of survival to discharge in the OLMC group. During the calls, the discussion of crucial prognostic factors, including witness status, initial rhythm, ETCO2, and arrest duration, appears inconsistent.

Conclusions: Pediatric-OHCA cases with OLMC tend to contact OLMC late in the resuscitation, have poor prognostic factors, and have poor survival outcomes. The information exchanged during OLMC calls was highly variable, representing a clear opportunity for improvement. Future studies should explore the potential effect of early OLMC contact on patient outcomes and if a standardized template for OLMC data exchange improves consistency in recommendations for P-OHCA.

研究目的我们的研究详细介绍了小儿院外心脏骤停(P-OHCA)在线医疗咨询(OLMC)的使用情况,包括使用 OLMC 的小儿院外心脏骤停比例、使用 OLMC 的病例特征、OLMC 呼叫中交换的信息类型以及急诊医疗服务(EMS)联系 OLMC 的患者的治疗结果:研究对象包括参与地区心脏登记的急救医疗机构所治疗的 P-OHCA 患者,这些机构的总覆盖人口约为 150 万居民。我们审查了从 2018 年 1 月 1 日到 2022 年 12 月 31 日接受治疗的 P-OHCA 病例的链接呼叫和 EMS 病历:最终分析共纳入了 2018 年 1 月至 2022 年 12 月期间的 112 个病例。112 例中有 22 例使用了 OLMC,从 9-1-1 呼叫到 OLMC 的平均时间为 28.8 分钟。无 OLMC 组的转运率明显高于 OLMC 组,任何时间的 ROSC 百分比和到达急诊室时的 ROSC 百分比也更高。无 OLMC 组的入院存活率和出院存活率都更高,而 OLMC 组则没有出院存活率。在通话过程中,对关键预后因素(包括目击者状态、初始心律、ETCO2和心跳骤停持续时间)的讨论似乎并不一致:结论:使用 OLMC 的小儿 OHCA 病例往往在复苏后期才与 OLMC 联系,预后因素差,存活率低。在 OLMC 通话中交换的信息差异很大,这显然是一个改进的机会。未来的研究应探讨早期联系 OLMC 对患者预后的潜在影响,以及 OLMC 数据交换的标准化模板是否能提高 P-OHCA 建议的一致性。
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引用次数: 0
Retrospective Review of the Image Quality of Monoplane Transesophageal Echocardiography in Prehospital Out-of-Hospital Cardiac Arrest: A Single Center Pilot Study. 院外心脏骤停院前单平面经食道超声心动图图像质量回顾性研究:单中心试点研究
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-11-01 DOI: 10.1080/10903127.2024.2411720
Kristopher Bianconi, Mark Hanna, Gautam Visveswaran, Reenal Patel, Joseph Pompa, Alec Glucksman, Garrett Cavaliere, Matthew Steenberg, Ammundeep Tagore, Navin Ariyaprakai

Objectives: Out of Hospital Cardiac Arrest (OHCA) is a frequently encountered pathology with resultant poor outcomes in the majority of patients. Echocardiography has been utilized to help guide clinical decision making and monitor effectiveness of resuscitative efforts. Transthoracic echocardiography (TTE) the mainstay of point-of-care ultrasound (POCUS) real time resuscitative imaging has limitations, most notably is the disruption of closed chest compressions. Trans-esophageal echocardiography (TEE) is an emerging technology in emergency care and can potentially overcome these limitations but image quality and accuracy of use in the prehospital environment remains unknown. Our primary objective is to identify the accuracy of Emergency Medical Services (EMS) fellow physicians in performing TEE via the identification of key cardiac structures. Secondarily we assess image quality as well as accuracy on cardiac activity interpretation as compared to TEE-experienced cardiologists.

Methods: A pilot study using descriptive analysis of a retrospective case-series with specific focus on inter-rater reliability as well as pragmatic management alterations based on real-time image interpretation by EMS physicians. After focused education, 13 patients were eligible for prehospital TEE who suffering OHCA from July 2022 to June 2023. Ultrasound (US) images were interpreted by EMS fellow physicians and over-read by cardiologists with specific focus on inter-rater reliability. After collection of patients presenting data and US images, analysis was performed.

Results: Of 13 patients initially screened, 10 patients were included in a study with a median age of 50 years old (41-70). Three patients were excluded due to equipment malfunction or insufficient image capture. An interrater reliability identified a kappa of 0.96 with respect to identification of cardiac structures and a kappa of 0.65 for identification of cardiac activity.

Conclusions: In this small study of prehospital TEE, EMS fellow physicians had high inter-rater reliability in image interpretation pertaining to anatomy and cardiac activity when compared with cardiologists. Further research is needed to determine its efficacy, safety, and widespread application in the prehospital setting.

目的:院外心脏骤停(OHCA)是一种经常遇到的病理现象,大多数患者的预后都很差。超声心动图已被用来帮助指导临床决策和监测复苏工作的效果。经胸超声心动图(TTE)是护理点超声(POCUS)实时复苏成像的主要手段,但也有其局限性,最明显的是会破坏闭式胸外按压。经食道超声心动图(TEE)是急救领域的一项新兴技术,有可能克服这些局限性,但在院前环境中使用的图像质量和准确性仍是未知数。我们的主要目标是通过识别关键心脏结构来确定急诊医疗服务 (EMS) 研究员在进行 TEE 时的准确性。其次,与有 TEE 经验的心脏病专家相比,我们将评估图像质量以及心脏活动解读的准确性:方法:这是一项对回顾性病例系列进行描述性分析的试验性研究,重点关注评分者之间的可靠性,以及根据急救医生的实时图像判读对实际管理做出的改变。2022 年 7 月至 2023 年 6 月期间,13 名患者在接受集中教育后符合院前 TEE 的条件,并发生了 OHCA。超声波(US)图像由急救医生进行解读,并由心脏病专家进行复读,重点关注评分者之间的可靠性。在收集了患者陈述数据和超声图像后,进行了分析:在初步筛选出的 13 名患者中,有 10 名患者被纳入研究,他们的中位年龄为 50 岁(41-70 岁)。三名患者因设备故障或图像采集不足而被排除。在识别心脏结构方面,研究人员之间的卡帕值为 0.96,在识别心脏活动方面,卡帕值为 0.65:在这项院前 TEE 的小型研究中,与心脏病专家相比,急救医疗研究员在解剖学和心脏活动的图像解读方面具有很高的评分者间可靠性。要确定其有效性、安全性以及在院前环境中的广泛应用,还需要进一步的研究。
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引用次数: 0
Benefits of Virtual Reality Training for Cardiopulmonary Resuscitation Skill Acquisition and Maintenance. 虚拟现实培训对心肺复苏技能学习和保持的益处。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-11-01 DOI: 10.1080/10903127.2024.2416971
Nai Zhang, Guiying Ye, Chuang Yang, Peng Zeng, Tao Gong, Lu Tao, Ying Zheng, Yujuan Liu

Objectives: To investigate the benefits of virtual reality (VR) first-aid training in acquiring cardiopulmonary resuscitation (CPR) skills.

Methods: A total of 100 non-medical professional volunteers from Nanchang were selected in March 2021 using the convenience sampling method. They were randomly divided into two groups: the VR training group (VR group) and the traditional simulation scenario training group (traditional group). The VR Group underwent immersive virtual reality CPR training with interactive feedback, while the Traditional Group received standard simulation-based CPR training using mannequins and instructor guidance. After training, relevant data were collected for comparative analysis.

Results: The study revealed that the VR group consistently outperforming the traditional group in theoretical knowledge test (cardiac arrest recognition, chest compressions, airway management, and artificial respiration) scores at 1, 3, 6, and 12 months post-training (p < 0.05). Similarly, the VR group showed superior performance in overall skills test scores and individual CPR quality metrics at all post-training assessments. The VR group scored higher in total skills, assessment, post-resuscitation assessment, chest compressions (at 1, 3, and 6 months), airway opening, and artificial respiration compared to the traditional group (p < 0.05). Despite these findings, both groups exhibited a gradual decrease in skills test scores over time.

Conclusions: Virtual reality training can significantly improve non-medical professional volunteers' CPR knowledge and skill levels, helping them master and maintain these competencies. However, a decrease in CPR knowledge and skills among the participants over time was observed after VR training, suggesting the need for further retraining sessions.

目的:研究虚拟现实(VR)急救培训对掌握心肺复苏(CPR)技能的益处:研究虚拟现实(VR)急救培训对掌握心肺复苏(CPR)技能的益处:方法:采用便利抽样法,于 2021 年 3 月从南昌市选取 100 名非医疗专业志愿者。他们被随机分为两组:VR 训练组(VR 组)和传统模拟场景训练组(传统组)。VR 组接受交互式反馈的沉浸式虚拟现实心肺复苏培训,而传统组则接受标准的模拟心肺复苏培训,使用人体模型并由教师指导。培训结束后,收集相关数据进行对比分析:研究显示,在培训后的 1、3、6 和 12 个月,VR 组在理论知识测试(心脏骤停识别、胸外按压、气道管理和人工呼吸)得分上一直优于传统组(P < 0.05)。同样,在培训后的所有评估中,VR 组在技能测试总分和单项心肺复苏质量指标上都表现优异。与传统组相比,VR 组在总技能、评估、复苏后评估、胸外按压(1、3 和 6 个月)、气道开放和人工呼吸方面得分更高(P < 0.05)。尽管有这些发现,但随着时间的推移,两组的技能测试分数都逐渐下降:结论:虚拟现实培训可以大大提高非医疗专业志愿者的心肺复苏知识和技能水平,帮助他们掌握并保持这些能力。然而,在接受虚拟现实培训后,参与者的心肺复苏知识和技能会随着时间的推移而下降,这表明有必要进行进一步的再培训。
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引用次数: 0
Burden of Non-Protocolized Patient Transport Outside of Response Area on a Rural Emergency Medical Services System. 非协议病人转运至响应区域外给农村急救系统带来的负担》(The Burden of Non-Protocolized Patient Transport Out of Response Area on a Rural EMS System)。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-10-30 DOI: 10.1080/10903127.2024.2412837
H Hill Stoecklein, Isabel C Shimanski, Christopher K Ryba, Joseph E Carnell, Scott T Youngquist

Objectives: Transport destination decisions by prehospital personnel depend on a combination of protocols, judgment, patient acuity, and patient preference. Non-protocolized transport outside the service area may result in unnecessary time out of service and inappropriate resource utilization. Scant research exists regarding clinician rationale for destination decisions.

Methods: We retrospectively reviewed one year of scene transports by a single rural, hospital-based emergency medical services (EMS) system. We collected dispatch, patient demographic, primary impression, and transport data from prehospital records and matched them to emergency department (ED) data. We characterized rationale for transport decisions and compared rates of hospital admission and specialist consultation in the ED as surrogates for decision appropriateness.

Results: We reviewed 2,223 patient transports, 281 of which were transported out of the service area. The most common reasons for out-of-area transport were patient preference NOT related to prior medical care (40%) and clinician judgment (24%). Admit rates were highest for per protocol (85%) and patient preference related to prior medical care (67%) groups and lowest for no explanation (41%) and clinician judgment (47%) groups. Rates of in person specialist consultation in the ED were highest in per protocol (69%) and clinician judgment (47%) groups and lowest in no explanation (23%) and patient preference NOT related to prior medical care (30%) groups. Clinician judgment was less predictive of admission and specialist consultation for non-trauma and pediatric patients than for all patients. Median time out of service was more than twice as long for out-of-area transports (140 min) compared to patients transported to the nearest facility (62 min). For out-of-area transports discharged from the ED without specialty consultation (n = 104), ambulances traveled an additional 52 miles/patient compared to theoretical transport to nearest facility.

Conclusions: Unit out of service time more than doubled for non-protocolized transports outside of the service area and rationale for destination decisions variably predicted admission and specialist consultation rates. Patient preference NOT related to prior medical care and, in pediatric and non-trauma populations, clinician judgment, were less predictive of admission and specialist consultation. Transport guidelines should balance rationale for transport destination and patient characteristics with resource preservation, especially in low-resource systems.

目的:院前人员决定转运目的地取决于协议、判断、患者病情严重程度和患者偏好的综合因素。在服务区之外进行非协议转运可能会导致不必要的服务中断时间和不适当的资源利用。有关临床医生决定目的地的理由的研究很少:我们回顾性地检查了一个以医院为基础的农村急救系统一年来的现场转运情况。我们从院前记录中收集了调度、患者人口统计、主要印象和转运数据,并将其与急诊科(ED)数据进行比对。我们描述了转运决定的合理性,并比较了入院率和急诊科专家会诊率,以此作为决定适当性的替代指标:我们审查了 2,223 次患者转运,其中 281 次转运至服务区以外。最常见的区域外转运原因是与既往医疗无关的患者偏好(40%)和临床医生的判断(24%)。按照协议(85%)和患者偏好与先前医疗相关(67%)组的入院率最高,无解释(41%)和临床医生判断(47%)组的入院率最低。在急诊室亲自接受专家会诊的比例,按方案组(69%)和临床医生判断组(47%)最高,无解释组(23%)和患者偏好与既往医疗无关组(30%)最低。与所有患者相比,临床医生的判断对非创伤和儿科患者的入院和专家会诊的预测性较低。地区外转运病人的中位服务时间(140 分钟)是转运到最近设施的病人(62 分钟)的两倍多。对于从急诊室出院但未接受专科会诊的区外转运患者(n = 104),与理论上转运至最近的医疗机构相比,救护车每运送一名患者多行驶了52英里:结论:在服务区以外的非协议转运中,单位服务外时间增加了一倍多,而目的地决定的理由可不同程度地预测入院率和专科会诊率。患者的偏好与之前的医疗护理无关,在儿科和非创伤人群中,临床医生的判断对入院和专家会诊的预测性较低。转运指南应在转运目的地的合理性和患者特征与资源保护之间取得平衡,尤其是在资源匮乏的系统中。
{"title":"Burden of Non-Protocolized Patient Transport Outside of Response Area on a Rural Emergency Medical Services System.","authors":"H Hill Stoecklein, Isabel C Shimanski, Christopher K Ryba, Joseph E Carnell, Scott T Youngquist","doi":"10.1080/10903127.2024.2412837","DOIUrl":"10.1080/10903127.2024.2412837","url":null,"abstract":"<p><strong>Objectives: </strong>Transport destination decisions by prehospital personnel depend on a combination of protocols, judgment, patient acuity, and patient preference. Non-protocolized transport outside the service area may result in unnecessary time out of service and inappropriate resource utilization. Scant research exists regarding clinician rationale for destination decisions.</p><p><strong>Methods: </strong>We retrospectively reviewed one year of scene transports by a single rural, hospital-based emergency medical services (EMS) system. We collected dispatch, patient demographic, primary impression, and transport data from prehospital records and matched them to emergency department (ED) data. We characterized rationale for transport decisions and compared rates of hospital admission and specialist consultation in the ED as surrogates for decision appropriateness.</p><p><strong>Results: </strong>We reviewed 2,223 patient transports, 281 of which were transported out of the service area. The most common reasons for out-of-area transport were patient preference NOT related to prior medical care (40%) and clinician judgment (24%). Admit rates were highest for per protocol (85%) and patient preference related to prior medical care (67%) groups and lowest for no explanation (41%) and clinician judgment (47%) groups. Rates of in person specialist consultation in the ED were highest in per protocol (69%) and clinician judgment (47%) groups and lowest in no explanation (23%) and patient preference NOT related to prior medical care (30%) groups. Clinician judgment was less predictive of admission and specialist consultation for non-trauma and pediatric patients than for all patients. Median time out of service was more than twice as long for out-of-area transports (140 min) compared to patients transported to the nearest facility (62 min). For out-of-area transports discharged from the ED without specialty consultation (<i>n</i> = 104), ambulances traveled an additional 52 miles/patient compared to theoretical transport to nearest facility.</p><p><strong>Conclusions: </strong>Unit out of service time more than doubled for non-protocolized transports outside of the service area and rationale for destination decisions variably predicted admission and specialist consultation rates. Patient preference NOT related to prior medical care and, in pediatric and non-trauma populations, clinician judgment, were less predictive of admission and specialist consultation. Transport guidelines should balance rationale for transport destination and patient characteristics with resource preservation, especially in low-resource systems.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Establishing Outcome Parameters for Helicopter Emergency Medical Services Research in The Netherlands: Results of a Mixed-Methods Delphi Consensus Study. 为荷兰直升机紧急医疗服务研究建立结果参数:混合方法德尔菲共识研究的结果。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-10-24 DOI: 10.1080/10903127.2024.2413038
Niek J Vianen, J Reinout Campfens, Margot Brouwer-Bergsma, Jan C Van Ditshuizen, Georgios F Giannakopoulos, Nico Hoogerwerf, Dennis den Hartog, Esther M M Van Lieshout, Iscander M Maissan, Patrick Schober, Lieneke Venema, Michael H J Verhofstad, Mark G Van Vledder

Objectives: Physician staffed Helicopter Emergency Medical Services (P-HEMS) care in the Netherlands has transitioned from predominantly trauma management to handling a variety of medical conditions. Relevant outcome parameters for Dutch P-HEMS research have not been previously defined. National consensus was sought to identify relevant long term patient outcome parameters, process outcome parameters and performance outcome parameters for Dutch P-HEMS care.

Methods: This was a mixed methods Delphi consensus study. A list of potentially relevant outcome parameters was identified using a systematic literature review. These parameters were subsequently surveyed in a Delphi consensus study. Helicopter Emergency Medical Services physicians and relevant stakeholders were invited to participate in this Delphi survey, where they were allowed to suggest additional outcome parameters. Descriptive analysis was performed on all data sets.

Results: Forty-nine potential outcome parameters for Dutch P-HEMS care were surveyed. Of 71 invited participants, 53 (75%), 40 (56%), and 20 (28%) participated in the first, second, and third round of the Delphi study, respectively. Consensus was reached on 25 (51%) of 49 outcome parameters as being important. These consisted of seven long term patient related outcome parameters, four short term patient related outcome parameters, five process outcome parameters and nine performance outcome parameters.

Conclusions: In conclusion, this study identified 25 outcome parameters relevant for Dutch physician staffed HEMS care. These parameters should be considered when designing future studies and should be routinely collected for each dispatch if possible.

目的:荷兰由医生组成的直升机紧急医疗服务(P-HEMS)已从主要处理创伤过渡到处理各种医疗状况。荷兰 P-HEMS 研究的相关结果参数之前尚未确定。我们寻求全国共识,以确定荷兰 P-HEMS 护理的相关长期患者结果参数、过程结果参数和绩效结果参数:这是一项德尔菲共识研究。通过系统的文献综述,确定了一份可能相关的结果参数清单。随后在德尔菲共识研究中对这些参数进行了调查。直升机紧急医疗服务医生和相关利益方应邀参加了此次德尔菲调查,他们可以提出更多的结果参数建议。对所有数据集进行了描述性分析:结果:对荷兰 P-HEMS 护理的 49 个潜在结果参数进行了调查。在 71 名受邀参与者中,分别有 53 人(75%)、40 人(56%)和 20 人(28%)参加了第一、第二和第三轮德尔菲研究。在 49 个重要结果参数中,有 25 个(51%)达成了共识。其中包括 7 个与患者相关的长期结果参数、4 个与患者相关的短期结果参数、5 个过程结果参数和 9 个绩效结果参数:总之,本研究确定了 25 项与荷兰医生配备的急救医疗服务相关的结果参数。在设计未来的研究时应考虑这些参数,并应尽可能对每次派遣进行常规收集。
{"title":"Establishing Outcome Parameters for Helicopter Emergency Medical Services Research in The Netherlands: Results of a Mixed-Methods Delphi Consensus Study.","authors":"Niek J Vianen, J Reinout Campfens, Margot Brouwer-Bergsma, Jan C Van Ditshuizen, Georgios F Giannakopoulos, Nico Hoogerwerf, Dennis den Hartog, Esther M M Van Lieshout, Iscander M Maissan, Patrick Schober, Lieneke Venema, Michael H J Verhofstad, Mark G Van Vledder","doi":"10.1080/10903127.2024.2413038","DOIUrl":"10.1080/10903127.2024.2413038","url":null,"abstract":"<p><strong>Objectives: </strong>Physician staffed Helicopter Emergency Medical Services (P-HEMS) care in the Netherlands has transitioned from predominantly trauma management to handling a variety of medical conditions. Relevant outcome parameters for Dutch P-HEMS research have not been previously defined. National consensus was sought to identify relevant long term patient outcome parameters, process outcome parameters and performance outcome parameters for Dutch P-HEMS care.</p><p><strong>Methods: </strong>This was a mixed methods Delphi consensus study. A list of potentially relevant outcome parameters was identified using a systematic literature review. These parameters were subsequently surveyed in a Delphi consensus study. Helicopter Emergency Medical Services physicians and relevant stakeholders were invited to participate in this Delphi survey, where they were allowed to suggest additional outcome parameters. Descriptive analysis was performed on all data sets.</p><p><strong>Results: </strong>Forty-nine potential outcome parameters for Dutch P-HEMS care were surveyed. Of 71 invited participants, 53 (75%), 40 (56%), and 20 (28%) participated in the first, second, and third round of the Delphi study, respectively. Consensus was reached on 25 (51%) of 49 outcome parameters as being important. These consisted of seven long term patient related outcome parameters, four short term patient related outcome parameters, five process outcome parameters and nine performance outcome parameters.</p><p><strong>Conclusions: </strong>In conclusion, this study identified 25 outcome parameters relevant for Dutch physician staffed HEMS care. These parameters should be considered when designing future studies and should be routinely collected for each dispatch if possible.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-14"},"PeriodicalIF":2.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proportional Versus Fixed Chest Compression Depth for Guideline-Compliant Resuscitation of Infant Asphyxial Cardiac Arrest. 符合指南的婴儿窒息性心脏骤停复苏按比例胸外按压深度与固定胸外按压深度。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-10-24 DOI: 10.1080/10903127.2024.2414391
David D Salcido, Allison C Koller, Cornelia Genbrugge, Jorge A Gumucio, James J Menegazzi

Objectives: Current guidelines for parameters of the delivery of chest compressions (CC) for infants and children are largely consensus based. Of the two recommended depth targets - 1.5 inches and 1/3 anterior-posterior chest diameter (APD) - it is unclear whether these have equal potential for injury. In previous experiments, our group showed in an animal model of pediatric asphyxial out-of-hospital cardiac arrest (OHCA; modeling ∼ 7 year-old children) that 1/3 APD resulted in significantly deeper CC and a higher likelihood of life-threatening injury. We sought to examine and compare injury characteristics of CC delivered at 1.5 inches or 1/3 APD in an infant model of asphyxial OHCA.

Methods: Swine were sedated, anesthetized, paralyzed, intubated through direct laryngoscopy, and then mechanically ventilated (10 ml/kg, FiO2:21%). APD was measured and confirmed by two investigators via a sliding T-square at the xiphoid. After instrumentation for vital signs monitoring, and while still anesthetized, the endotracheal tube was manually occluded to induce asphyxia, and occlusion was maintained for 9 min. Animals were then randomized to receive CC with a depth of 1.5 inches (Group 1) or 1/3 APD (Group 2), both with a rate of 100 per minute. Advanced life support drugs were administered at 13 min, and defibrillation at 14 min. Resuscitation continued until return of spontaneous circulation (ROSC) or 20 min of failed resuscitation. Survivors were sacrificed with KCl after 20 min of observation. Veterinary staff conducted necropsy to assay lung injury, rib fracture, hemothorax, airway bleeding, great vessel dissection, and heart/liver/spleen contusion. Injury characteristics were summarized and compared via Chi-Squared test or Mann-Whitney U-test using an alpha = 0.05.

Results: A total of 36 animals were included for analysis (Group 1: 18; Group 2: 18). Mean (SD) APD overall was 5.58 (0.23) inches, yielding a mean 1/3 APD depth of 1.86 inches. APD did not differ between groups. ROSC rates did not differ between groups. No injury characteristics differed significantly between groups.

Conclusions: In an swine model of infant asphyxial OHCA and resuscitation considering 1/3 APD or 1.5 inches, neither CC depth strategy was associated with increased injury.

目的:目前为婴儿和儿童提供的胸外按压 (CC) 参数指南主要基于共识。在推荐的两个深度目标(1.5 英寸和 1/3 胸前后直径 (APD))中,目前尚不清楚这两个目标是否具有同等的伤害可能性。在之前的实验中,我们的研究小组在小儿院外窒息性心脏骤停(OHCA;建模 ∼ 7 岁儿童)的动物模型中发现,1/3 APD 会导致 CC 明显加深,造成危及生命的损伤的可能性更高。我们试图在窒息性 OHCA 婴儿模型中研究和比较 1.5 英寸或 1/3 APD 下的 CC 损伤特征:方法:对猪进行镇静、麻醉、瘫痪、通过直接喉镜插管,然后进行机械通气(10 毫升/千克,FiO2:21%)。两名研究人员通过剑突部位的滑动 T 形尺测量并确认 APD。在使用仪器进行生命体征监测后,在仍处于麻醉状态的情况下,手动闭塞气管导管以诱导窒息,并保持闭塞 9 分钟。然后将动物随机分配到深度为 1.5 英寸的 CC(第 1 组)或 1/3 APD(第 2 组),速度均为每分钟 100 次。13 分钟时给予高级生命支持药物,14 分钟时进行除颤。复苏一直持续到自发性循环恢复(ROSC)或复苏失败 20 分钟。观察 20 分钟后,用氯化钾将幸存者处死。兽医人员进行尸体解剖,以检测肺损伤、肋骨骨折、血胸、气道出血、大血管离断和心/肝/脾挫伤。通过 Chi-Squared 检验或 Mann-Whitney U 检验(α = 0.05)对损伤特征进行总结和比较:共有 36 只动物被纳入分析(第 1 组:18 只;第 2 组:18 只)。总体 APD 平均值(标清)为 5.58 (0.23) 英寸,1/3 APD 平均深度为 1.86 英寸。各组的 APD 无差异。各组的 ROSC 率没有差异。各组间的损伤特征无明显差异:结论:在一个婴儿窒息 OHCA 和复苏考虑 1/3 APD 或 1.5 英寸的猪模型中,两种 CC 深度策略都不会增加损伤。
{"title":"Proportional Versus Fixed Chest Compression Depth for Guideline-Compliant Resuscitation of Infant Asphyxial Cardiac Arrest.","authors":"David D Salcido, Allison C Koller, Cornelia Genbrugge, Jorge A Gumucio, James J Menegazzi","doi":"10.1080/10903127.2024.2414391","DOIUrl":"10.1080/10903127.2024.2414391","url":null,"abstract":"<p><strong>Objectives: </strong>Current guidelines for parameters of the delivery of chest compressions (CC) for infants and children are largely consensus based. Of the two recommended depth targets - 1.5 inches and 1/3 anterior-posterior chest diameter (APD) - it is unclear whether these have equal potential for injury. In previous experiments, our group showed in an animal model of pediatric asphyxial out-of-hospital cardiac arrest (OHCA; modeling ∼ 7 year-old children) that 1/3 APD resulted in significantly deeper CC and a higher likelihood of life-threatening injury. We sought to examine and compare injury characteristics of CC delivered at 1.5 inches or 1/3 APD in an infant model of asphyxial OHCA.</p><p><strong>Methods: </strong>Swine were sedated, anesthetized, paralyzed, intubated through direct laryngoscopy, and then mechanically ventilated (10 ml/kg, FiO2:21%). APD was measured and confirmed by two investigators <i>via</i> a sliding T-square at the xiphoid. After instrumentation for vital signs monitoring, and while still anesthetized, the endotracheal tube was manually occluded to induce asphyxia, and occlusion was maintained for 9 min. Animals were then randomized to receive CC with a depth of 1.5 inches (Group 1) or 1/3 APD (Group 2), both with a rate of 100 per minute. Advanced life support drugs were administered at 13 min, and defibrillation at 14 min. Resuscitation continued until return of spontaneous circulation (ROSC) or 20 min of failed resuscitation. Survivors were sacrificed with KCl after 20 min of observation. Veterinary staff conducted necropsy to assay lung injury, rib fracture, hemothorax, airway bleeding, great vessel dissection, and heart/liver/spleen contusion. Injury characteristics were summarized and compared <i>via</i> Chi-Squared test or Mann-Whitney U-test using an alpha = 0.05.</p><p><strong>Results: </strong>A total of 36 animals were included for analysis (Group 1: 18; Group 2: 18). Mean (SD) APD overall was 5.58 (0.23) inches, yielding a mean 1/3 APD depth of 1.86 inches. APD did not differ between groups. ROSC rates did not differ between groups. No injury characteristics differed significantly between groups.</p><p><strong>Conclusions: </strong>In an swine model of infant asphyxial OHCA and resuscitation considering 1/3 APD or 1.5 inches, neither CC depth strategy was associated with increased injury.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-7"},"PeriodicalIF":2.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prehospital Trauma Compendium: Management of the Entrapped Patient - a Position Statement and Resource Document of NAEMSP. 创伤简编:被夹病人的管理 - NAEMSP 的立场声明和资料文件。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-10-24 DOI: 10.1080/10903127.2024.2413876
Nichole Bosson, Benjamin N Abo, Troy D Litchfield, Zaffer Qasim, Matthew F Steenberg, Jake Toy, Antonia Osuna-Garcia, John Lyng

Entrapped patients may be simply entombed or experiencing crush injury or entanglement. Patients with trauma who are entrapped are at higher risk of significant injury than patients not entrapped. Limited access and prolonged scene times further complicate patient management. Although patient entrapment is a significant focus of specialty teams, such as urban search & rescue (US&R) teams that operate as local, regional, and/or national resources in response to complex scenes and disaster scenarios, entrapment is a regular occurrence in routine EMS response. Therefore, all EMS clinicians must have the training and skills to manage entrapped patients and to support medically-directed rescue throughout the extrication process. NAEMSP RECOMMENDSEMS clinicians must perform a timely and thorough primary and secondary assessment and reassessments in parallel with dynamic extrication planning; the environment may require adaption of standard assessment techniques and devices.EMS clinicians should establish early, clear, and ongoing communications with rescue personnel to ensure a coordinated patient-centered medically directed approach to extrication. Communication with the patient should be frequent, clear, and reassuring.EMS clinicians should immediately take measures to effectively prevent and manage hypothermia.EMS clinicians should recognize airway management in the entrapped patient is always challenging. When required, advanced airway placement should be performed by the most experienced operator with proficiency in multiple modalities and alternative techniques in limited access situations.In entrapped patients who are experiencing or are at risk for crush syndrome, EMS clinicians should initiate large-volume (i.e., 1-1.5 L/h for adults and 20 mL/kg/h for pediatric patients for the initial 3-4 h) fluid resuscitation with crystalloid, preferably normal saline, as early as possible and prior to extrication.In entrapped patients who are experiencing or are at risk for crush syndrome, EMS clinicians should administer medications to mitigate risks of hyperkalemia, infection, and renal failure, early and prior to extrication.Tourniquet application should be considered in the setting of the crushed extremity as a potential adjunct to medical optimization before extrication of some patients.Patients with prolonged entrapment with the potential for severe injuries require complex resuscitation and may benefit from EMS physician management on scene. EMS systems should consider an early EMS physician response to entrapped patients.

被卡住的病人可能只是被卡住,也可能遭受挤压伤或缠绕。与未被缠绕的病人相比,被缠绕的创伤病人受重伤的风险更高。有限的通道和冗长的现场时间使患者管理更加复杂。虽然病人被卡住是专业团队(如城市搜救(US&R)团队)关注的重点,这些团队作为地方、区域和/或国家资源应对复杂的现场和灾难场景,但在常规急救响应中,病人被卡住是经常发生的事情。因此,所有 EMS 临床医生都必须接受培训并掌握相关技能,以便在整个解救过程中管理被困患者并支持以医疗为导向的救援。NAEMSP 建议:EMS 临床医生必须在制定动态解救计划的同时,及时进行全面的初级和二级评估及再评估;环境可能需要对标准评估技术和设备进行调整。EMS 临床医生应与救援人员建立早期、清晰和持续的沟通,以确保在解救过程中采取以患者为中心的协调医疗导向方法。急救医疗人员应立即采取措施,有效预防和控制体温过低。急救医疗人员应认识到,对被困患者进行气道管理始终是一项挑战。需要时,应由最有经验的操作员进行高级气道置入,他们应熟练掌握多种模式,并在通道有限的情况下使用替代技术、对于正在经历挤压综合症或有此风险的被困患者,急救医疗人员应在解救前尽早使用晶体液(最好是正常生理盐水)进行大容量液体复苏(即成人 1-1.5 升/小时,儿童患者 20 毫升/千克/小时,持续 3-4 小时)。在对某些患者进行解救之前,应考虑在肢体挤压的情况下使用止血带,作为医疗优化的潜在辅助手段。有可能造成严重伤害的长时间被困患者需要进行复杂的复苏,并可能受益于急救医生在现场的管理。急救系统应考虑让急救医生尽早对被困患者做出反应。
{"title":"Prehospital Trauma Compendium: Management of the Entrapped Patient - a Position Statement and Resource Document of NAEMSP.","authors":"Nichole Bosson, Benjamin N Abo, Troy D Litchfield, Zaffer Qasim, Matthew F Steenberg, Jake Toy, Antonia Osuna-Garcia, John Lyng","doi":"10.1080/10903127.2024.2413876","DOIUrl":"10.1080/10903127.2024.2413876","url":null,"abstract":"<p><p>Entrapped patients may be simply entombed or experiencing crush injury or entanglement. Patients with trauma who are entrapped are at higher risk of significant injury than patients not entrapped. Limited access and prolonged scene times further complicate patient management. Although patient entrapment is a significant focus of specialty teams, such as urban search & rescue (US&R) teams that operate as local, regional, and/or national resources in response to complex scenes and disaster scenarios, entrapment is a regular occurrence in routine EMS response. Therefore, all EMS clinicians must have the training and skills to manage entrapped patients and to support medically-directed rescue throughout the extrication process. NAEMSP RECOMMENDSEMS clinicians must perform a timely and thorough primary and secondary assessment and reassessments in parallel with dynamic extrication planning; the environment may require adaption of standard assessment techniques and devices.EMS clinicians should establish early, clear, and ongoing communications with rescue personnel to ensure a coordinated patient-centered medically directed approach to extrication. Communication with the patient should be frequent, clear, and reassuring.EMS clinicians should immediately take measures to effectively prevent and manage hypothermia.EMS clinicians should recognize airway management in the entrapped patient is always challenging. When required, advanced airway placement should be performed by the most experienced operator with proficiency in multiple modalities and alternative techniques in limited access situations.In entrapped patients who are experiencing or are at risk for crush syndrome, EMS clinicians should initiate large-volume (i.e., 1-1.5 L/h for adults and 20 mL/kg/h for pediatric patients for the initial 3-4 h) fluid resuscitation with crystalloid, preferably normal saline, as early as possible and prior to extrication.In entrapped patients who are experiencing or are at risk for crush syndrome, EMS clinicians should administer medications to mitigate risks of hyperkalemia, infection, and renal failure, early and prior to extrication.Tourniquet application should be considered in the setting of the crushed extremity as a potential adjunct to medical optimization before extrication of some patients.Patients with prolonged entrapment with the potential for severe injuries require complex resuscitation and may benefit from EMS physician management on scene. EMS systems should consider an early EMS physician response to entrapped patients.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-13"},"PeriodicalIF":2.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142472916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Prehospital Rearrest With Outcome Following Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis of Observational Studies. 院外心脏骤停后院前再次搏动与预后的关系:观察性研究的系统回顾和荟萃分析。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-10-18 DOI: 10.1080/10903127.2024.2408628
Tanner Smida, Sahil Dayal, James Bardes, James Scheidler

Objectives: Exposure to prehospital rearrest has previously been associated with mortality following out-of-hospital cardiac arrest (OHCA). Our objective was to conduct a systematic review and meta-analysis examining the association between prehospital rearrest and survival in adults following OHCA resuscitation.

Methods: We searched the PubMed, Scopus, and Web of Science bibliographic databases for observational studies that included adult OHCA patients who achieved return of spontaneous circulation in the prehospital setting following OHCA and reported survival to hospital discharge data stratified by rearrest status. The primary exposure was prehospital rearrest. The primary outcome for this study was survival to hospital discharge. Secondary outcomes included survival with a favorable neurological outcome and rearrest prevalence. We pooled data using inverse heterogeneity modeling and presented effect sizes for the survival outcomes as odds ratios with 95% confidence intervals. We quantified heterogeneity using Cochran's Q and the I2 statistic and examined small study effects using Doi plots and the LFK index.

Results: Of the 84 publications screened, we included 7 observational studies containing 27,045 patients with survival to hospital discharge data. Rearrest was common (30% [18-43%]; n = 7 studies; Q = 1086.1, p < 0.001; I2 = 99%; LFK index = 1.21) and associated with both decreased odds of survival to discharge (pooled aOR: 0.27 [0.22, 0.33]; n = 7 studies; Q = 32.2, p < 0.01, I2 = 81%, LFK index = -0.08) and decreased odds of survival to discharge with a favorable neurological outcome (pooled aOR: 0.25, [0.22, 0.28]; n = 4 studies; Q = 3.5, p = 0.3; I2 = 13%, LFK index = 1.30).

Conclusions: Rearrest is common and associated with decreased survival following OHCA. The pooled result of this meta-analysis suggests that preventing rearrest in five patients would be necessary to save one life.

目的:院前再次急救与院外心脏骤停(OHCA)后的死亡率有关。我们的目的是进行一项系统性综述和荟萃分析,研究院前再次心搏骤停与成人院外心脏骤停复苏后存活率之间的关系:我们在PubMed、Scopus和Web of Science文献数据库中搜索了一些观察性研究,这些研究纳入了OHCA后在院前环境中自发循环恢复的成人OHCA患者,并报告了按再次心肺复苏状态分层的出院生存率数据。主要暴露是院前再次跌倒。本研究的主要结果是出院后的存活率。次要结果包括良好神经功能结果的存活率和再次rest发生率。我们使用反异质性模型对数据进行了汇总,并将生存结果的效应大小以几率比和 95% 置信区间的形式呈现。我们使用 Cochran's Q 和 I2 统计量对异质性进行了量化,并使用 Doi 图和 LFK 指数检查了小规模研究的效应:在筛选出的 84 篇文献中,我们共纳入了 7 项观察性研究,包含 27,045 名患者的出院生存数据。再次复发很常见(30% [18-43%];n = 7 项研究;Q = 1086.1,p 2=99%;LFK 指数 = 1.21),并且与出院存活率下降有关(汇总 aOR:0.27 [0.22,0.33];n = 7 项研究;Q = 32.2,p 2=81%,LFK 指数=-0.08),以及出院后神经系统结果良好的存活几率降低(汇总 aOR:0.25,[0.22,0.28];n=4 项研究;Q=3.5,p=0.3;I2=13%,LFK 指数=1.30):结论:重袭很常见,与 OHCA 后存活率下降有关。这项荟萃分析的汇总结果表明,防止五名患者再次猝死才能挽救一条生命:CRD42024525048。
{"title":"Association of Prehospital Rearrest With Outcome Following Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis of Observational Studies.","authors":"Tanner Smida, Sahil Dayal, James Bardes, James Scheidler","doi":"10.1080/10903127.2024.2408628","DOIUrl":"10.1080/10903127.2024.2408628","url":null,"abstract":"<p><strong>Objectives: </strong>Exposure to prehospital rearrest has previously been associated with mortality following out-of-hospital cardiac arrest (OHCA). Our objective was to conduct a systematic review and meta-analysis examining the association between prehospital rearrest and survival in adults following OHCA resuscitation.</p><p><strong>Methods: </strong>We searched the PubMed, Scopus, and Web of Science bibliographic databases for observational studies that included adult OHCA patients who achieved return of spontaneous circulation in the prehospital setting following OHCA and reported survival to hospital discharge data stratified by rearrest status. The primary exposure was prehospital rearrest. The primary outcome for this study was survival to hospital discharge. Secondary outcomes included survival with a favorable neurological outcome and rearrest prevalence. We pooled data using inverse heterogeneity modeling and presented effect sizes for the survival outcomes as odds ratios with 95% confidence intervals. We quantified heterogeneity using Cochran's Q and the I<sup>2</sup> statistic and examined small study effects using Doi plots and the LFK index.</p><p><strong>Results: </strong>Of the 84 publications screened, we included 7 observational studies containing 27,045 patients with survival to hospital discharge data. Rearrest was common (30% [18-43%]; <i>n</i> = 7 studies; <i>Q</i> = 1086.1, p < 0.001; I<sup>2</sup> = 99%; LFK index = 1.21) and associated with both decreased odds of survival to discharge (pooled aOR: 0.27 [0.22, 0.33]; <i>n</i> = 7 studies; <i>Q</i> = 32.2, p < 0.01, I<sup>2</sup> = 81%, LFK index = -0.08) and decreased odds of survival to discharge with a favorable neurological outcome (pooled aOR: 0.25, [0.22, 0.28]; <i>n</i> = 4 studies; <i>Q</i> = 3.5, p = 0.3; I<sup>2</sup> = 13%, LFK index = 1.30).</p><p><strong>Conclusions: </strong>Rearrest is common and associated with decreased survival following OHCA. The pooled result of this meta-analysis suggests that preventing rearrest in five patients would be necessary to save one life.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Route to ROSC: Evaluating the Impact of Route and Timing of Epinephrine Administration in Out-of-Hospital Cardiac Arrest Outcomes. 通往 ROSC 的途径:评估肾上腺素给药途径和时机对院外心脏骤停结果的影响。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-10-14 DOI: 10.1080/10903127.2024.2414389
Michael W Hubble, Melisa D Martin, Ginny R Kaplan, Sara E Houston, Stephen E Taylor

Objectives: Previous investigations comparing intraosseous (IO) and intravenous (IV) epinephrine delivery in out-of-hospital cardiac arrest (OHCA) suggest that epinephrine is oftentimes more expeditiously administered via the IO route, but this temporal benefit doesn't always translate to clinical benefit. However, very few studies adequately controlled for indication and resuscitation time biases, making the influence of first epinephrine route on OHCA outcomes unclear. To determine the association between first epinephrine route and return of spontaneous circulation (ROSC) while controlling for resuscitation time bias and other potential confounders.

Methods: We conducted a retrospective analysis using the 2020 ESO Data Collaborative dataset. Adult patients with a witnessed, non-traumatic OHCA prior to EMS arrival were included. Logistic regression was used to determine the association between medication route and ROSC. Linear regression was then used to calculate the probability of ROSC for each route across all call receipt-to-drug delivery intervals. Using these linear equations, the call receipt-to-drug delivery intervals were calculated that would yield equivalent probabilities of ROSC between the IV and IO routes.

Results: Data were available for 10,350 patients, of which 27.4% presented with a shockable rhythm, 29.7% received bystander CPR, and 39.6% experienced ROSC. After controlling for confounders, IO epinephrine was associated with decreased likelihood of ROSC (OR = 0.77, p < 0.001). The linear regression models provided differing slope coefficients for ROSC between each route, with the IV route associated with a higher likelihood of ROSC for any given call receipt-to-drug-delivery interval. From these equations, the additional time allowed to establish an IV and administer epinephrine intravenously beyond the time required for IO delivery, yet with an equivalent predicted probability of ROSC via the IO route, was calculated. This additional time interval for intravenous administration declined linearly from 9 min at a call receipt-to-intraosseous epinephrine interval of 4 min to no additional time at a call receipt-to-intraosseous epinephrine interval of 29 min.

Conclusions: This retrospective analysis of a national EMS database revealed that IO epinephrine was negatively associated with ROSC. Additionally, there appears to be a finite time window during which intravenous epinephrine remains superior to the intraosseous route even if there are brief initial delays in IV drug delivery.

目的:之前的研究比较了院外心脏骤停(OHCA)中的鞘内(IO)和静脉(IV)肾上腺素给药,结果表明通过 IO 途径给药肾上腺素通常更快,但这种时间上的优势并不总能转化为临床获益。然而,很少有研究充分控制了适应症和复苏时间的偏差,因此首次肾上腺素给药途径对 OHCA 结果的影响尚不明确。目的是在控制复苏时间偏差和其他潜在混杂因素的同时,确定首次肾上腺素途径与自发性循环恢复(ROSC)之间的关系:我们利用 2020 年 ESO 数据协作组数据集进行了一项回顾性分析。研究纳入了在急救中心到达之前发生有目击者在场的非创伤性 OHCA 的成人患者。采用逻辑回归确定用药途径与 ROSC 之间的关系。然后使用线性回归法计算从接到呼叫到药物交付的所有时间间隔内每种途径的 ROSC 概率。利用这些线性方程,计算出了静脉注射和虹吸管途径之间产生同等 ROSC 概率的呼叫接收到药物交付时间间隔:我们获得了 10,350 名患者的数据,其中 27.4% 的患者出现了可电击心律,29.7% 的患者接受了旁观者心肺复苏术,39.6% 的患者出现了 ROSC。在控制了混杂因素后,IO 肾上腺素与 ROSC 的可能性降低有关(OR = 0.77,p 结论:这项对全国急救数据库的回顾性分析表明,IO 肾上腺素与 ROSC 呈负相关。此外,静脉注射肾上腺素似乎有一个有限的时间窗口,在此期间,即使静脉给药最初出现短暂延迟,静脉注射肾上腺素仍优于鞘内途径。
{"title":"The Route to ROSC: Evaluating the Impact of Route and Timing of Epinephrine Administration in Out-of-Hospital Cardiac Arrest Outcomes.","authors":"Michael W Hubble, Melisa D Martin, Ginny R Kaplan, Sara E Houston, Stephen E Taylor","doi":"10.1080/10903127.2024.2414389","DOIUrl":"10.1080/10903127.2024.2414389","url":null,"abstract":"<p><strong>Objectives: </strong>Previous investigations comparing intraosseous (IO) and intravenous (IV) epinephrine delivery in out-of-hospital cardiac arrest (OHCA) suggest that epinephrine is oftentimes more expeditiously administered <i>via</i> the IO route, but this temporal benefit doesn't always translate to clinical benefit. However, very few studies adequately controlled for indication and resuscitation time biases, making the influence of first epinephrine route on OHCA outcomes unclear. To determine the association between first epinephrine route and return of spontaneous circulation (ROSC) while controlling for resuscitation time bias and other potential confounders.</p><p><strong>Methods: </strong>We conducted a retrospective analysis using the 2020 ESO Data Collaborative dataset. Adult patients with a witnessed, non-traumatic OHCA prior to EMS arrival were included. Logistic regression was used to determine the association between medication route and ROSC. Linear regression was then used to calculate the probability of ROSC for each route across all call receipt-to-drug delivery intervals. Using these linear equations, the call receipt-to-drug delivery intervals were calculated that would yield equivalent probabilities of ROSC between the IV and IO routes.</p><p><strong>Results: </strong>Data were available for 10,350 patients, of which 27.4% presented with a shockable rhythm, 29.7% received bystander CPR, and 39.6% experienced ROSC. After controlling for confounders, IO epinephrine was associated with decreased likelihood of ROSC (OR = 0.77, <i>p</i> < 0.001). The linear regression models provided differing slope coefficients for ROSC between each route, with the IV route associated with a higher likelihood of ROSC for any given call receipt-to-drug-delivery interval. From these equations, the additional time allowed to establish an IV and administer epinephrine intravenously beyond the time required for IO delivery, yet with an equivalent predicted probability of ROSC <i>via</i> the IO route, was calculated. This additional time interval for intravenous administration declined linearly from 9 min at a call receipt-to-intraosseous epinephrine interval of 4 min to no additional time at a call receipt-to-intraosseous epinephrine interval of 29 min.</p><p><strong>Conclusions: </strong>This retrospective analysis of a national EMS database revealed that IO epinephrine was negatively associated with ROSC. Additionally, there appears to be a finite time window during which intravenous epinephrine remains superior to the intraosseous route even if there are brief initial delays in IV drug delivery.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Workplace Violence Against Emergency Medical Services (EMS): A Prospective 12-Month Cohort Study Evaluating Prevalence and Risk Factors Within a Large, Multistate EMS Agency. 针对紧急医疗服务 (EMS) 的工作场所暴力:一项为期 12 个月的前瞻性队列研究,评估了一个大型多州紧急医疗服务机构内的普遍性和风险因素。
IF 2.1 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-10-09 DOI: 10.1080/10903127.2024.2411020
Sarayna S McGuire, Fernanda Bellolio, Bradley J Buck, Chad P Liedl, Dayne D Stuhr, Aidan F Mullan, Mykell Ryan Buffum, Casey M Clements

Objectives: To determine the prevalence and associated risk factors of workplace violence (WPV) experienced by emergency medical services (EMS) clinicians across a large, multistate ground/air EMS agency.

Methods: We used a prospective cohort study design from 1 December 2022 to 30 November 2023. A checkbox was added within the electronic medical record (EMR) asking staff to indicate whether WPV occurred. Patient characteristics, encounter (run), and crew factors were abstracted. Potential risk factors for WPV were assessed using logistic regression, with the occurrence of any form of violence as the primary outcome of interest. Models were both univariable, assessing each risk factor individually, and multivariable, assessing all risk factors together to identify independent factors associated with higher risk of WPV. Multivariable model results were reported using adjusted odds ratios (aORs) and 95% confidence intervals.

Results: A total of 102,632 runs were included, 95.7% (n = 98,234) included checkbox documentation. There were 843 runs (0.86 per 100 runs, 95% CI 0.80-0.92) identified by EMS clinicians as WPV having occurred, including verbal abuse (n = 482), physical assault (n = 142), and both abuse and assault (n = 219). Risk factors for violence included male patient gender (aOR 1.45, 95% CI 1.24-1.70, p < 0.001), Richmond Agitation-Sedation Scale (RASS) >1 (aOR 16.97, 95% CI 13.71-21.01, p < 0.001), and 9-1-1 runs to include emergent (P1; aOR 1.75, 95% CI: 1.17-2.63, p = 0.007) and urgent (P2; aOR 1.64, 95% CI 1.08-2.50, p = 0.021) priority, compared to P3/scheduled transfer or P4/trip requests. Factors associated with lower risk for violence included older patients (aOR per 10 years = 0.95, 95% CI 0.91-0.98, p = 0.007) and run time of day between 0601-1200 h compared to 0000-0600 h (aOR 0.67, 95% CI 0.51-0.88, p = 0.004). Only 2.7% of violent runs captured through the EMR were reported through official processes.

Conclusions: Verbal and/or physical violence is recognized in nearly 1% of EMS runs. We recommend prioritizing WPV prevention and mitigation strategies around identified risk factors and simplifying the WPV reporting process in order to reduce staff administrative burden and encourage optimal capturing of violent events.

目的确定一个大型多州地面/空中紧急医疗服务机构的紧急医疗服务(EMS)临床医生所经历的工作场所暴力(WPV)的发生率和相关风险因素:我们采用了前瞻性队列研究设计,研究时间为 2022 年 12 月 1 日至 2023 年 11 月 30 日。电子病历(EMR)中增加了一个复选框,要求工作人员指出是否发生了 WPV。研究人员抽取了患者特征、就诊(运行)情况和机组人员因素。使用逻辑回归法评估 WPV 的潜在风险因素,并将发生任何形式的暴力行为作为主要关注结果。模型包括单变量模型和多变量模型,前者对每个风险因素进行单独评估,后者对所有风险因素进行综合评估,以确定与较高 WPV 风险相关的独立因素。多变量模型结果采用几率比(aORs)和 95% 置信区间进行报告:共纳入 102,632 次运行,95.7%(n= 98,234 次)包含复选框文档。有 843 次(每 100 次 0.86,95% CI 0.80-0.92)急救医生确认发生过 WPV,包括辱骂(n= 482)、殴打(n= 142)以及辱骂和殴打(n= 219)。暴力行为的风险因素包括男性患者性别(aOR 1.45,95% CI 1.24 - 1.70,p 1(aOR 16.97,95% CI 13.71 - 21.01,p 结论):在近 1%的急救服务中发现了言语和/或肢体暴力。我们建议围绕已识别的风险因素优先制定 WPV 预防和缓解策略,并简化 WPV 报告流程,以减轻员工的行政负担,鼓励以最佳方式捕获暴力事件。
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Prehospital Emergency Care
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