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Advancing Prehospital Pediatric Readiness: Formation and Future Directions of the Prehospital Pediatric Readiness Project. 推进院前儿科准备:院前儿科准备项目的形成和未来方向。
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-13 DOI: 10.1080/10903127.2026.2630377
Rachael Alter, Katherine Remick, Caleb Ward, Ann Dietrich, Sylvia Owusu-Ansah, Brian Moore, Kathleen Adelgais, Marianne Gausche-Hill

Emergency services leaders have long recognized the importance of timely, high-quality care for critically ill and injured children. The establishment of the federal Emergency Medical Services for Children Program in 1985 has helped disseminate and promote the adoption of pediatric emergency care standards nationwide for the past four decades. Additional efforts were further driven by an impactful report by the Institute of Medicine in 2006: Emergency Care for Children: Growing Pains, which outlined key recommendations to improve pediatric emergency care. In response, the National Pediatric Readiness Project (NPRP) launched in 2011, providing a roadmap for emergency departments to improve pediatric care. Following the success of the NPRP, national organizations collaborated to address pediatric emergency care in the prehospital setting and published a set of recommendations in a 2020 joint policy statement, accompanied by a technical report that summarized the evidence behind the recommendations. Subsequently, the National Prehospital Pediatric Readiness Project (PPRP) was initiated to implement these recommendations. The work of this project has resulted in the development and dissemination of a comprehensive checklist, a corresponding toolkit, and a first-of-its-kind nationwide assessment of prehospital Pediatric Readiness. We describe here the scope of the PPRP, along with a description of future directions, including disseminating assessment results, supporting emergency medical services agency quality improvement efforts, research opportunities, and building a sustainable infrastructure to ensure all emergency medical service agencies are equipped to deliver high-quality emergency care to children.

急救服务的领导人早就认识到及时、高质量护理危重儿童和受伤儿童的重要性。1985年建立的联邦儿童紧急医疗服务方案在过去四十年中帮助传播和促进了全国儿童紧急护理标准的采用。医学研究所2006年发表的一份有影响力的报告《儿童急诊护理:成长的烦恼》进一步推动了进一步的努力,其中概述了改善儿科急诊护理的主要建议。为此,2011年启动了国家儿科准备项目(NPRP),为急诊科提供了改善儿科护理的路线图。在NPRP取得成功之后,国家组织合作解决院前儿科急诊问题,并在2020年联合政策声明中发布了一系列建议,并附有一份技术报告,总结了这些建议背后的证据。随后,启动了国家院前儿科准备项目(PPRP),以执行这些建议。该项目的工作已形成并传播了一份全面的检查清单、相应的工具包,并首次在全国范围内对儿科院前准备情况进行了评估。我们在这里描述了PPRP的范围,以及对未来方向的描述,包括传播评估结果,支持紧急医疗服务机构质量改进工作,研究机会,以及建立可持续的基础设施,以确保所有紧急医疗服务机构都有能力为儿童提供高质量的紧急护理。
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引用次数: 0
A Simulation-Based Root Cause Analysis of Pediatric Medication Dosing Errors in Emergency Medical Services. 急诊医疗服务中儿科用药剂量错误的模拟根本原因分析
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-10 DOI: 10.1080/10903127.2026.2634106
Bryan M Harmer, John D Hoyle, Lee Wells, Tycho Fredericks, Autumn Edwards, Adam Lecznar, Kathryn Christopher, Sue Dunwoody, Guan Hong, William Rantz, Vitaliy Popov, Prashant Mahajan, Kieran Fogarty

Objectives: Prehospital pediatric medication administration (PMA) carries a persistent dosing error rate of approximately 31%, despite efforts to mitigate these events. While the characteristics of these errors are well documented, underlying latent conditions in the emergency medical services (EMS) system contributing to these errors are not well understood. The purpose of this study is to identify the root causes within the EMS system that contribute to these errors.

Methods: This study builds upon our previous mixed-methods simulation-based study that identified the frequency and characteristics of active errors associated with PMA. Eleven two-person EMS crews from two agencies in Michigan each completed three simulated pediatric emergencies requiring two doses of epinephrine, midazolam, or fentanyl. Simulations were recorded, and a physician and paramedic measured the accuracy of dosage administration. Post-simulation interviews were conducted to investigate actions associated with error and potential contributing factors. A multidisciplinary team analyzed equipment, protocols, interviews, observer notes, and participant comments through a modified Delphi method, identifying latent conditions using a Root Cause Analysis and Action framework and categorized them using a human factors framework.

Results: Latent conditions were identified and categorized after two rounds of the modified Delphi method. These conditions were found in all five tiers of the human factors framework. They included: 1) Individual Characteristics: limited clinician experience, knowledge, stress, and anxiety; 2) Nature of Work: high task complexity and limited teamwork; 3) Human-System Interface: cognitive aid and medical device usability issues; 4) Management: limited employee training and development; and 5) External Environment: protocol issues and a lack of assistive technology.

Conclusions: These results highlight the critical systemic vulnerabilities underlying PMA dosing errors in EMS, supporting that errors result from systemic issues rather than solely from individual actions. By addressing these systemic weaknesses with comprehensive strategies, progress can be made in effectively resolving the ongoing issue of PMA dosing errors in EMS.

目的:院前儿科给药(PMA)持续的给药错误率约为31%,尽管努力减轻这些事件。虽然这些错误的特征被很好地记录下来,但紧急医疗服务(EMS)系统中导致这些错误的潜在条件尚未得到很好的理解。本研究的目的是找出EMS系统中导致这些错误的根本原因。方法:本研究建立在我们之前的基于混合方法模拟的研究基础上,该研究确定了与PMA相关的主动误差的频率和特征。来自密歇根州两家机构的11名双人急救人员分别完成了三次模拟儿科紧急情况,需要两剂肾上腺素、咪达唑仑或芬太尼。模拟记录下来,医生和护理人员测量给药的准确性。模拟后的访谈是为了调查与错误相关的行为和潜在的促成因素。多学科团队通过改进的德尔菲法分析设备、协议、访谈、观察员笔记和参与者评论,使用根本原因分析和行动框架识别潜在条件,并使用人为因素框架对其进行分类。结果:经过两轮改进的德尔菲法对潜在条件进行了识别和分类。在人为因素框架的所有五个层次中都发现了这些情况。它们包括:1)个体特征:有限的临床经验、知识、压力和焦虑;2)工作性质:任务复杂性高,团队合作有限;3)人机界面:认知辅助和医疗器械可用性问题;4)管理:有限的员工培训和发展;外部环境:协议问题,缺乏辅助技术。结论:这些结果突出了EMS中PMA剂量错误背后的关键系统脆弱性,支持错误是由系统问题引起的,而不仅仅是由个人行为引起的。通过综合策略解决这些系统性弱点,可以在有效解决EMS中PMA给药错误的持续问题方面取得进展。
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引用次数: 0
Physiological Demands of Canadian Armed Forces Reserve Medics During Simulated Tactical Combat Casualty Care. 加拿大武装部队后备医务人员在模拟战术战斗伤员护理中的生理需求。
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-10 DOI: 10.1080/10903127.2026.2628839
Tyler Adams, Hannah Cameron, Hans Christian Tingelstad, Matthew Peter Belgiorgio, Tara Reilly

Objectives: The objective of this study was to measure the physiological demands of reserve medics performing tactical combat casualty care (TCCC) within evacuation scenarios.

Methods: Seven active reservist medics (three female) in the Canadian Armed Forces (CAF) completed three self-paced TCCC scenarios developed by a casualty evacuation subject matter expert, based on one- and multi-person evacuations determined to be the most relevant to current CAF operations. Patrol and stretcher carry, trench evacuation, and vehicle extrication were performed on three consecutive days. The casualty was an 86.1 kg manikin dressed in military attire. Participants performed a 1-kilometer pre-fatigue approach march prior to the "patrol" and "trench evacuation" scenario. Oxygen consumption (VO2) and heart rate (HR) were measured continuously, and rating of perceived exertion (RPE) were recorded at the end.

Results: Participants' mean age was 26 ± 5 years, mean height 179.7 ± 9.6 cm, and mean unloaded mass 83.4 ± 12.2 kg. They wore minimal tactical equipment weighing 27.0 ± 2.1 kg. The patrol scenario total time was 12 ± 2 min, mean relative VO2 was 26.4 ± 5.8 mL/kg/min (load adjusted 19.6 ± 4.1 mL/kg/min), which was 54% of estimated VO2max, and mean HR was 166.0 ± 11.3 bpm (88% of HRmax). Final RPE was 16.0 ± 0.8. The trench scenario total time was 12 ± 2 min, mean relative VO2 was 30.2 ± 4.0 mL/kg/min (load adjusted 22.8 ± 2.5 mL/kg/min), which was 64% of estimated VO2max, and mean HR was 159.0 ± 13.7 bpm (84% of HRmax). Final RPE was 16.4 ± 1.1. The vehicle extrication scenario total time was 102 ± 25 s, mean relative VO2 was 22.2 ± 5.5 mL/kg/min (load adjusted 18.2 ± 4.4 mL/kg/min), which was 46% of estimated VO2max, and mean HR was 153.0 ± 15.8 bpm (81% of HRmax). Final RPE was 13.4 ± 1.1.

Conclusions: Reserve medic TCCC training scenarios demonstrate high relative physiological demand as determined through directly measured VO2 and HR. The VO2 demands of these tasks exceed those required to successfully perform the CAF physical employment standard. Due to these physiological requirements, occupational training courses should prioritize combining fitness training at a relatively high intensity with medical tasks to best simulate the occupational environment.

目的:本研究的目的是测量在疏散情景下执行战术战斗伤亡护理(TCCC)的后备医务人员的生理需求。方法:加拿大武装部队(CAF)的7名现役预备役医务人员(3名女性)完成了3个自定进度的TCCC场景,该场景由一名伤员疏散主题专家开发,基于确定与当前CAF行动最相关的一人和多人疏散。巡逻和担架运送、战壕疏散和车辆解救连续进行了三天。死者是一个重达86.1公斤、身穿军装的人体模型。在“巡逻”和“战壕疏散”场景之前,参与者进行了1公里的疲劳前行军。连续测量各组的耗氧量(VO2)和心率(HR),最后记录各组的感觉运动评分(RPE)。结果:参与者平均年龄26±5岁,平均身高179.7±9.6 cm,平均体重83.4±12.2 kg。他们穿着最小的战术装备,重27.0±2.1公斤。巡逻场景总时间为12±2 min,平均相对VO2为26.4±5.8 mL/kg/min(负荷调整19.6±4.1 mL/kg/min),为估计VO2max的54%,平均HR为166.0±11.3 bpm (HRmax的88%)。最终RPE为16.0±0.8。壕沟情景总时间为12±2 min,平均相对VO2为30.2±4.0 mL/kg/min(负荷调整22.8±2.5 mL/kg/min),为估计VO2max的64%,平均HR为159.0±13.7 bpm (HRmax的84%)。最终RPE为16.4±1.1。车辆解救场景总时间为102±25秒,平均相对VO2为22.2±5.5 mL/kg/min(负荷调整18.2±0.4 mL/kg/min),为估计VO2max的46%,平均HR为153.0±15.8 bpm (HRmax的81%)。最终RPE为13.4±1.1。结论:后备医务人员TCCC训练场景具有较高的相对生理需求,可以通过直接测量VO2和HR来确定。这些任务的VO2需求超过了成功执行CAF物理使用标准所需的VO2需求。由于这些生理要求,职业训练课程应优先考虑将较高强度的健身训练与医疗任务相结合,以最好地模拟职业环境。
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引用次数: 0
A Retrospective Comparison of Plunger-Type and Band-Type Mechanical Chest Compression Devices for Prehospital Resuscitation. 回顾性比较柱塞式和带式机械胸外按压装置在院前复苏中的应用。
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-10 DOI: 10.1080/10903127.2026.2637173
Tanner Smida, Ryley Handyside, Remle Crowe, Patrick W Merrill, James Scheidler, James Bardes

Objectives: Mechanical CPR (mCPR) device use during the resuscitation of out-of-hospital cardiac arrest (OHCA) patients is increasing in the United States. Multiple device types are commercially available, but limited data exist investigating the association between device type and patient outcomes. We aimed to compare the outcomes of patients treated with band-type and plunger-type mCPR devices.

Methods: We used the ESO Data Collaborative 2022-2024 annual datasets for this retrospective cohort study. We included all adult (18-80 years), non-traumatic OHCA patients treated with mCPR following a 9-1-1 call. We excluded patients if they had a resuscitation-limiting advanced directive, experienced OHCA in a nursing home or health care facility, or achieved ROSC prior to mCPR device use. We classified patients into treatment groups based on the mCPR device type used during resuscitation, and used patients treated with plunger-type devices as the reference group for all analyses. Our primary outcome was prehospital return of spontaneous circulation (ROSC). To compare these devices, we used a multi-level mixed effects logistic regression model with emergency medical services agency as a random intercept and adjusted for age, sex, race, witnessed status, bystander CPR, etiology, response interval, initial ECG, interval from scene arrival to mCPR device initiation, OHCA location, year, attempted airway management prior to mCPR, initial airway management strategy, initial vascular access strategy, medication administration prior to mCPR, and agency characteristics.

Results: After application of exclusion criteria, 38,561 patients were eligible for analysis (4,010 (10.4%) treated with band-type devices). Our cohort was a median 62 (50-71) years of age, 33.9% female, 45.5% had witnessed OHCA, 34.5% received bystander CPR, 20.9% presented with a shockable rhythm, and the median time from scene arrival to mCPR initiation was 4.8 (3.0-7.7) minutes. The use of a band-type device was associated with lower odds of achieving prehospital ROSC (band-type: 894/4,010 (22.3%) vs. plunger-type: 8,446/34,551 (24.5%); aOR: 0.87 (0.78, 0.96)).

Conclusions: Our study suggested that the use of a band-type mCPR device was associated with a small decrease in odds of achieving prehospital ROSC in comparison to the use of a plunger-type device. Limitations include the potential for residual confounding, unmeasured confounders, and selection bias.

目的:在美国,院外心脏骤停(OHCA)患者复苏期间机械心肺复苏术(mCPR)装置的使用正在增加。市面上有多种设备类型,但调查设备类型与患者预后之间关系的数据有限。我们的目的是比较带式和柱塞式mCPR装置治疗患者的结果。方法:我们使用ESO数据协作2022-2024年度数据集进行回顾性队列研究。我们纳入了所有的成人(18-80岁),非创伤性OHCA患者在接到9-1-1电话后接受mCPR治疗。我们排除了那些有限制复苏的高级指令,在养老院或医疗机构经历过OHCA,或在使用mCPR设备之前达到ROSC的患者。我们根据复苏过程中使用的mCPR装置类型将患者分为治疗组,并将柱塞式装置治疗的患者作为所有分析的参照组。我们的主要终点是院前自然循环恢复(ROSC)。为了比较这些设备,我们使用了一个多级混合效应logistic回归模型,以紧急医疗服务机构作为随机截距,并调整了年龄、性别、种族、目击者状态、旁观者CPR、病因、反应间隔、初始心电图、从现场到达到mCPR设备启动的间隔、OHCA位置、年份、mCPR之前尝试的气道管理、初始气道管理策略、初始血管通路策略、mCPR之前的药物管理、以及机构特征。结果:应用排除标准后,38,561例患者符合分析条件,其中4010例(10.4%)使用带式器械。我们的队列中位年龄为62岁(50-71岁),33.9%为女性,45.5%曾经历过OHCA, 34.5%接受过旁观者CPR, 20.9%出现过休克节律,从到达现场到mCPR启动的中位时间为4.8(3.0-7.7)分钟。使用带式装置实现院前ROSC的几率较低(带式:894/4,010(22.3%),而柱塞式:8,446/34,551 (24.5%);aOR: 0.87(0.78, 0.96))。结论:我们的研究表明,与使用柱塞式装置相比,使用带式mCPR装置与实现院前ROSC的几率略有降低相关。局限性包括潜在的残留混杂因素、未测量混杂因素和选择偏差。
{"title":"A Retrospective Comparison of Plunger-Type and Band-Type Mechanical Chest Compression Devices for Prehospital Resuscitation.","authors":"Tanner Smida, Ryley Handyside, Remle Crowe, Patrick W Merrill, James Scheidler, James Bardes","doi":"10.1080/10903127.2026.2637173","DOIUrl":"10.1080/10903127.2026.2637173","url":null,"abstract":"<p><strong>Objectives: </strong>Mechanical CPR (mCPR) device use during the resuscitation of out-of-hospital cardiac arrest (OHCA) patients is increasing in the United States. Multiple device types are commercially available, but limited data exist investigating the association between device type and patient outcomes. We aimed to compare the outcomes of patients treated with band-type and plunger-type mCPR devices.</p><p><strong>Methods: </strong>We used the ESO Data Collaborative 2022-2024 annual datasets for this retrospective cohort study. We included all adult (18-80 years), non-traumatic OHCA patients treated with mCPR following a 9-1-1 call. We excluded patients if they had a resuscitation-limiting advanced directive, experienced OHCA in a nursing home or health care facility, or achieved ROSC prior to mCPR device use. We classified patients into treatment groups based on the mCPR device type used during resuscitation, and used patients treated with plunger-type devices as the reference group for all analyses. Our primary outcome was prehospital return of spontaneous circulation (ROSC). To compare these devices, we used a multi-level mixed effects logistic regression model with emergency medical services agency as a random intercept and adjusted for age, sex, race, witnessed status, bystander CPR, etiology, response interval, initial ECG, interval from scene arrival to mCPR device initiation, OHCA location, year, attempted airway management prior to mCPR, initial airway management strategy, initial vascular access strategy, medication administration prior to mCPR, and agency characteristics.</p><p><strong>Results: </strong>After application of exclusion criteria, 38,561 patients were eligible for analysis (4,010 (10.4%) treated with band-type devices). Our cohort was a median 62 (50-71) years of age, 33.9% female, 45.5% had witnessed OHCA, 34.5% received bystander CPR, 20.9% presented with a shockable rhythm, and the median time from scene arrival to mCPR initiation was 4.8 (3.0-7.7) minutes. The use of a band-type device was associated with lower odds of achieving prehospital ROSC (band-type: 894/4,010 (22.3%) vs. plunger-type: 8,446/34,551 (24.5%); aOR: 0.87 (0.78, 0.96)).</p><p><strong>Conclusions: </strong>Our study suggested that the use of a band-type mCPR device was associated with a small decrease in odds of achieving prehospital ROSC in comparison to the use of a plunger-type device. Limitations include the potential for residual confounding, unmeasured confounders, and selection bias.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-8"},"PeriodicalIF":2.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147290633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the Influence of a Statewide Dosing Reference Aid on Prehospital Pediatric Medication Dosing Errors: A Mixed-Methods Simulation-Based Investigation. 评估全州剂量参考援助对院前儿童用药剂量错误的影响:一项基于混合方法模拟的调查。
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-09 DOI: 10.1080/10903127.2025.2599515
Bryan M Harmer, John D Hoyle, Autumn Edwards, Tycho Fredericks, Lee Wells, Adam Lecznar, Kathryn Christopher, Sue Dunwoody, Guan Hong, William Rantz, Vitaliy Popov, Prashant Mahajan, Kieran Fogarty

Objectives: Errors occur in 31% of prehospital pediatric medication administrations (PMA) in Michigan despite the implementation of the MI-MEDIC pediatric dosing reference aid. Reference aids may not effectively target the causes of dosing errors and could introduce new types of error. Our study examines the frequency, magnitude, and immediate causes of PMA dosing errors in emergency medical services (EMS) after implementation of the MI-MEDIC dosing reference aid.

Methods: We used a mixed method, mobile simulation-based approach to examine PMA dosing errors. Emergency medical services crews were recruited from a private EMS service and a fire-based EMS service in Michigan. Each crew completed three high-fidelity simulations (infant seizure, infant cardiac arrest and child burn) requiring two doses of midazolam, epinephrine, or fentanyl. Post-simulation interviews were conducted. Error rates and magnitudes were analyzed using descriptive statistics. A multidisciplinary team used a modified Delphi method, incorporating simulation observations, interview recordings, pictures of equipment that were used during the simulations, and protocols to categorize observed errors and reach consensus on their immediate causes.

Results: Eleven crews were recruited between both agencies, completing 33 simulations and 66 medication administrations, using the MI-MEDIC dosing reference aid. Dosing errors occurred in 19 of the 66 doses (28.8%), with 13 underdoses (68.4%) and six overdoses (31.6%). The median underdose was 0.50 (95% IQR: 0.20-0.56). The median overdose was 2.00 (95% IQR: 1.40-12.50). After two rounds, Delphi consensus categorized 13 slips (68.4%), six mistakes (31.6%), and no lapses. Immediate causes included crews obtaining the wrong weight (4/19, 21.0%), a large volume of air present in the syringe (6/19, 31.6%) and improper dilution of medications when following instructions on the MI-MEDIC reference aid (6/19, 31.6%). The remaining three involved epinephrine administration directly from the prefilled syringe system (2/19, 10.5%) and an intentional underdose (1/19, 5.3%).

Conclusions: PMA dosing errors persist at a high rate with the use of the MI-MEDIC dosing reference aid. Immediate causes of error involve incorrect weight, administering air, and improper dilution, which tools like the MI-MEDIC dosing reference aid do not address. Further research is needed to develop comprehensive strategies addressing the active errors identified in our study.

目的:尽管实施了MI-MEDIC儿科给药参考援助,但密歇根州院前儿科给药管理(PMA)的错误率为31%。参考辅助工具可能不能有效地针对剂量误差的原因,并可能引入新的误差类型。本研究探讨了在实施MI-MEDIC剂量参考援助后,紧急医疗服务(EMS)中PMA剂量错误的频率、程度和直接原因。方法:我们采用混合方法,基于移动模拟的方法来检查PMA给药误差。紧急医疗服务人员是从密歇根州的一家私人紧急医疗服务机构和一家基于火灾的紧急医疗服务机构招募的。每个工作人员完成了三个高保真模拟(婴儿癫痫发作、婴儿心脏骤停和儿童烧伤),需要两剂咪达唑仑、肾上腺素或芬太尼。模拟后进行了访谈。用描述性统计分析错误率和程度。一个多学科团队使用改进的德尔菲法,结合模拟观察、访谈记录、模拟过程中使用的设备图片和协议,对观察到的错误进行分类,并就其直接原因达成共识。结果:使用MI-MEDIC给药参考辅助工具,在两个机构之间招募11名工作人员,完成33次模拟和66次给药。66个剂量中有19个剂量错误(28.8%),13个剂量不足(68.4%),6个剂量过量(31.6%)。中位剂量不足为0.50 (95% IQR: 0.20-0.56)。中位用药过量为2.00 (95% IQR: 1.40-12.50)。两轮后,德尔菲共识分类出13个失误(68.4%),6个错误(31.6%),没有失误。直接原因包括工作人员获得错误的重量(4/ 19,21.0%),注射器中存在大量空气(6/ 19,31.6%),以及按照MI-MEDIC参考辅助手册的说明稀释药物不当(6/ 19,31.6%)。其余3例涉及直接从预充注射器系统给药(2/19,10.5%)和故意给药不足(1/19,5.3%)。结论:在使用MI-MEDIC给药参考辅助器具时,PMA给药误差居高不下。误差的直接原因包括不正确的重量、给药空气和不适当的稀释,这些都是MI-MEDIC给药参考辅助工具无法解决的。需要进一步的研究来制定全面的策略来解决我们研究中发现的主动错误。
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引用次数: 0
Riding into Reality: How Ride-alongs with Mobile Integrated Healthcare Shape Medical Student Understanding of Social Determinants of Health. 乘车进入现实:如何乘车与移动集成医疗塑造医学生对健康的社会决定因素的理解。
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-06 DOI: 10.1080/10903127.2026.2640174
Dieu Thao Nguyen, Mirinda Ann Gormley, Jose Correa-Ibarra, Page Bridges, Luke Estes, Martin Lutz

Objectives: Medical students rarely get the opportunity to witness the impact of social determinants of health (SDOH) on patients within their community. Mobile integrated healthcare (MIH) programs utilize community paramedics (CPs) to tackle patient-specific SDOH to promote continuity of care and linkage to treatment for patients lacking access to health care resources. This study discusses the creation of an MIH ride-along program for medical students and assesses whether ride-along participation would influence medical students' knowledge and perceptions of SDOH and the role SDOH play in accessing health care resources.

Methods: First- or second-year medical students in the Southeastern U.S. completed at least one 8-hour ride-along with the MIH program. Pre-shift surveys assessed baseline SDOH knowledge and post-shift surveys reassessed SDOH knowledge and documented students' perceptions on the educational value of the ride-along. Five key categories of SDOH assessed included: 1) education quality and access, 2) health care quality and access, 3) economic stability, 4) neighborhood and built environment and 5) social and community context. Paired T-tests assessed differences in the mean scores pre-test and post-test.

Results: The 33 participants were predominantly White (72.0%) and female (64.0%), with an average age of 26 (±3.84). Students conducted home visits (93.0%), medication reconciliations (67.0%), chronic disease education (48.0%), lab draws (48%), and social and resource referrals (35.0%) during ride-alongs. Nearly all (94.0%) reported the MIH program improved their understanding of all five SDOH categories and health care challenges within their community. All but one recommended permanent integration of MIH ride-alongs into the medical school curriculum.

Conclusions: Working alongside CPs to care for underserved patients increased medical student knowledge of SDOH and heightened awareness how SDOH impacts patients' health care within their local community. Most recommended integrating the MIH program into the medical school curriculum. Medical educators should consider incorporation of MIH interactions to enhance real-world experience with SDOH.

目的:医学生很少有机会目睹健康的社会决定因素(SDOH)对他们社区内患者的影响。移动综合医疗保健(MIH)方案利用社区护理人员(CPs)来解决患者特定的SDOH问题,以促进无法获得医疗保健资源的患者的护理连续性和治疗联系。本研究旨在探讨医学生医疗服务随车计划的建立,并评估随车参与是否会影响医学生对医疗服务随车的认识和认知,以及医疗服务随车在获取医疗资源中的作用。方法:美国东南部的一年级或二年级医学生完成了至少一次8小时的MIH项目骑行。轮班前的调查评估了基线SDOH知识,轮班后的调查重新评估了SDOH知识,并记录了学生对乘车教育价值的看法。SDOH评估的五个关键类别包括:1)教育质量和可及性;2)医疗质量和可及性;3)经济稳定性;4)邻里和建筑环境;5)社会和社区背景。配对t检验评估测试前和测试后平均得分的差异。结果:33例患者以白人(72.0%)和女性(64.0%)为主,平均年龄26岁(±3.84岁)。学生在陪同期间进行了家访(93.0%)、药物调解(67.0%)、慢性病教育(48.0%)、实验室检查(48%)和社会和资源转介(35.0%)。几乎所有(94.0%)的人都报告说,MIH项目提高了他们对所有五个SDOH类别和社区内卫生保健挑战的理解。除一人外,所有人都建议将MIH骑行永久纳入医学院课程。结论:与CPs一起照顾缺医少药的患者增加了医学生对SDOH的了解,并提高了SDOH如何影响当地社区患者医疗保健的认识。大多数人建议将MIH计划纳入医学院课程。医学教育工作者应考虑结合MIH的互动,以增强SDOH的实际经验。
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引用次数: 0
The Psychological Impact of Attending Out-of-Hospital Cardiac Arrest in Volunteer Lay Responders: A Mixed-Methods Systematic Review. 参与院外心脏骤停对志愿急救人员的心理影响:一项混合方法的系统评价。
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-06 DOI: 10.1080/10903127.2026.2640607
Paul du Toit, Karan Botsford, Joe Copson

Objectives:  To explore and describe the incidence of psychological impact, including post-traumatic stress-type symptoms, in volunteer lay responders following involvement with out-of-hospital cardiac arrest, and to identify factors influencing these outcomes.

Methods:  A convergent integrated mixed-methods systematic review was conducted (PROSPERO registration: CRD42023467307). APA PsycInfo, CINAHL (EBSCO), PubMed (Medline), and Web of Science were searched for studies published between January 2003 and October 2025. The Joanna Briggs Institute methodological approach guided study selection, quality appraisal, data extraction, and synthesis.

Results:  Twelve studies involving 80,742 participants from seven countries were included. Five key areas were identified: risk and prevalence of psychological impact; lay responder characteristics; situational dynamics; social connectedness and a sense of community; and emotions experienced while awaiting activation. Most studies reported low levels of severe psychological impact and individual characteristics, situational factors, and community support influenced psychological outcomes.

Conclusions: Severe psychological effects following out-of-hospital cardiac arrest were uncommon, but lay responders may experience mild-to-moderate distress influenced by demographics, situational exposure, and social support. This review highlights modifiable factors - targeted training, clear role expectations, and structured post-event support - that can mitigate psychological burden. Strengthening these areas is critical for protecting lay responders, enhancing the resilience of volunteer programs, and sustaining the Chain of Survival.

目的:探讨和描述院外心脏骤停后志愿者非专业急救人员的心理影响发生率,包括创伤后应激型症状,并确定影响这些结果的因素。方法:采用融合综合混合方法进行系统评价(PROSPERO注册号:CRD42023467307)。检索了2003年1月至2025年10月间发表的APA PsycInfo、CINAHL (EBSCO)、PubMed (Medline)和Web of Science。乔安娜布里格斯研究所的方法方法指导研究选择、质量评估、数据提取和综合。结果:12项研究包括来自7个国家的80,742名参与者。确定了五个关键领域:心理影响的风险和普遍程度;应答器特性;情境动力学;社会联系和社区意识;以及等待激活时的情绪体验。大多数研究报告了低水平的严重心理影响和个体特征、情境因素和社区支持影响心理结果。结论:院外心脏骤停后的严重心理影响并不常见,但外行急救人员可能会受到人口统计学、情境暴露和社会支持的影响而经历轻度至中度的痛苦。本综述强调了可改变的因素——有针对性的培训、明确的角色期望和结构化的事后支持——可以减轻心理负担。加强这些领域对于保护外行应急人员、增强志愿者项目的复原力和维持生存链至关重要。
{"title":"The Psychological Impact of Attending Out-of-Hospital Cardiac Arrest in Volunteer Lay Responders: A Mixed-Methods Systematic Review.","authors":"Paul du Toit, Karan Botsford, Joe Copson","doi":"10.1080/10903127.2026.2640607","DOIUrl":"https://doi.org/10.1080/10903127.2026.2640607","url":null,"abstract":"<p><strong>Objectives: </strong> To explore and describe the incidence of psychological impact, including post-traumatic stress-type symptoms, in volunteer lay responders following involvement with out-of-hospital cardiac arrest, and to identify factors influencing these outcomes.</p><p><strong>Methods: </strong> A convergent integrated mixed-methods systematic review was conducted (PROSPERO registration: CRD42023467307). APA PsycInfo, CINAHL (EBSCO), PubMed (Medline), and Web of Science were searched for studies published between January 2003 and October 2025. The Joanna Briggs Institute methodological approach guided study selection, quality appraisal, data extraction, and synthesis.</p><p><strong>Results: </strong> Twelve studies involving 80,742 participants from seven countries were included. Five key areas were identified: <i>risk and prevalence of psychological impact</i>; <i>lay responder characteristics; situational dynamics; social connectedness and a sense of community;</i> and <i>emotions experienced while awaiting activation</i>. Most studies reported low levels of severe psychological impact and individual characteristics, situational factors, and community support influenced psychological outcomes.</p><p><strong>Conclusions: </strong>Severe psychological effects following out-of-hospital cardiac arrest were uncommon, but lay responders may experience mild-to-moderate distress influenced by demographics, situational exposure, and social support. This review highlights modifiable factors - targeted training, clear role expectations, and structured post-event support - that can mitigate psychological burden. Strengthening these areas is critical for protecting lay responders, enhancing the resilience of volunteer programs, and sustaining the Chain of Survival.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-41"},"PeriodicalIF":2.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Intra-Arrest Glucose on Patient Outcomes in Out-of-Hospital Cardiac Arrest. 院外心脏骤停患者停搏内血糖对预后的影响
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-05 DOI: 10.1080/10903127.2026.2631180
Michael W Hubble, Sara E Houston, Stephen E Taylor, Melisa D Martin, Ginny R Kaplan, Randy D Kearns

Objectives: Cardiac arrest leads to an array of metabolic disturbances, including glucose metabolism. Intra-arrest blood glucose level (BGL) is rarely reported in out-of-hospital cardiac arrest (OHCA) literature, and the influence of BGL on patient outcomes has yet to be conclusively established. To describe the interrelationship between intra-arrest BGL, dextrose administration, and short-term outcomes.

Methods: A retrospective analysis of the 2020 ESO Data Collaborative Annual Research dataset was conducted that included adults who experienced non-traumatic arrests prior to emergency medical services (EMS) arrival and for whom at least one intra-arrest BGL was measured. Logistic regression was used to determine the association between BGL and return of spontaneous circulation (ROSC) while controlling for confounding variables. In this analysis, BGL was modeled with seven categories representing visually distinct bins of the unadjusted probability distribution of ROSC stratified by first intra-arrest glucose measurement.

Results: Data were available for 16,847 patients, of which presumed cardiac etiology was present in 81.6%, followed by respiratory/asphyxia (9.6%), drug overdose (5.0%), and other (3.7%). Most (62.0%) were males with a mean age of 63.5 (±16.7) years and a mean BGL of 184.4 (±104.8) mg/dL. Present in 20.0% was an initial shockable rhythm, while 25.8% received bystander cardiopulmonary resuscitation, and 35.9% attained ROSC. Compared to patients with BGLs of 161-300 mg/dL, patients with ≤50 mg/dL, 51-110 mg/dL, 111-160 mg/dL, 351-430 mg/dL, and ≥431mg/dL were less likely to attain ROSC (OR = 0.407, 0.543, 0.864, 0.718, 0.574, respectively, all p < 0.001). There was no association between ROSC and BGLs of 301-350 mg/dL compared to the reference category (OR = 0.862, p = 0.059). For cumulative BGL ≤ 90 mg/dL, no statistically significant difference in the odds of ROSC between those who received dextrose and those who did not was observed. For cumulative BGL values above 90 mg/dL, intra-arrest dextrose administration was associated with a lower odds of ROSC.

Conclusions: Within the limitations of our observational study design, these data suggest that an association exists between the likelihood of ROSC and intra-arrest BGL. However, this relationship does not appear to be improved with exogenous dextrose administration at any threshold of intra-arrest BGL. Additional study using more robust designs is warranted to further elucidate the interrelationship between BGL, dextrose administration, and longer-term patient outcomes.

目的:心脏骤停导致一系列代谢紊乱,包括葡萄糖代谢。院外心脏骤停(OHCA)文献很少报道停搏内血糖水平(BGL), BGL对患者预后的影响尚未得到最终确定。描述停搏期间BGL、葡萄糖给药和短期预后之间的相互关系。方法:对2020年ESO数据协作年度研究数据集进行回顾性分析,该数据集包括在紧急医疗服务(EMS)到达之前经历过非创伤性逮捕的成年人,并且至少测量过一次逮捕期间BGL。在控制混杂变量的同时,采用Logistic回归来确定BGL与自发循环(ROSC)之间的关系。在本分析中,BGL被建模为7个类别,这些类别代表由第一次停搏内血糖测量分层的ROSC未调整概率分布的视觉上不同的箱子。结果:共收集到16847例患者的资料,其中81.6%为心脏原因,其次为呼吸/窒息(9.6%)、药物过量(5.0%)和其他原因(3.7%)。男性居多(62.0%),平均年龄63.5(±16.7)岁,平均BGL为184.4(±104.8)mg/dL。20.0%的患者出现了最初的休克性心律,25.8%的患者接受了旁观者心肺复苏,35.9%的患者达到了ROSC。与BGL为161-300mg/dL的患者相比,≤50mg/dL、51-110mg/dL、111-160mg/dL、351-430mg/dL和≥431mg/dL的患者获得ROSC的可能性较低(OR分别为0.407、0.543、0.864、0.718、0.574,均为p)。结论:在我们观察性研究设计的局限性内,这些数据表明ROSC的可能性与骤停期BGL存在关联。然而,这种关系似乎并没有随着外源性葡萄糖给药在任何阈值内的BGL而得到改善。为了进一步阐明BGL、葡萄糖给药和患者长期预后之间的相互关系,需要使用更可靠的设计进行进一步的研究。
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引用次数: 0
Exploring Positive Experiences, Challenges, and Sustainability Measures in Inter-Organizational Collaboration: A Qualitative Study of Fire-Based Emergency Medical Service Agencies in Japan. 探索组织间协作中的积极经验、挑战和可持续性措施:日本火灾紧急医疗服务机构的定性研究。
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-05 DOI: 10.1080/10903127.2025.2598562
Keiko Ueno, Chie Teramoto, Junko Saito

Objectives: Community-dwelling populations in Japan are increasingly experiencing complex health and social challenges. Fire-based emergency medical service (EMS) agencies are encountering a growing number of socially vulnerable individuals and are emerging as key partners. However, evidence regarding the implementation and sustainability of such collaborations within Japanese communities remains limited. We aimed to explore the positive experiences and challenges of inter-organizational collaboration between fire-based EMS agencies and long-term care, welfare, and health organizations in Japan as well as strategies for its sustainability.

Methods: Semi-structured and joint interviews were conducted with 26 paramedics in administrative roles from 20 fire-based EMS agencies across Japan. These participants were licensed professionals with prior frontline experience who were currently assigned to divisions responsible for planning and coordinating EMS. They were purposively selected from fire-based EMS agencies that had responded to a nationwide survey. The interviews focused on experiences, challenges, and approaches related to collaboration with long-term care, welfare, and health organizations. Interviews were conducted via Zoom, transcribed verbatim, and analyzed using a qualitative descriptive approach. Codes were developed inductively, grouped into subcategories and overarching categories, and validated through member checking.

Results: Collaboration with community organizations was perceived to enhance EMS efficiency and responsiveness, strengthen interprofessional collaboration and mutual understanding, and promote the appropriate use of EMS by facilitating patient referral to relevant support services. Key challenges included ambiguity in coordination roles, limited operational capacity within partner organizations, insufficient interprofessional understanding, and inadequate information sharing. To sustain inter-organizational collaboration, participants emphasized the importance of promoting relationship building and mutual understanding, establishing sustainable inter-organizational collaboration framework, improving infrastructure for information sharing and triage support, clarifying the roles and response policies of fire-based EMS agencies, enhancing interprofessional education, and securing adequate human resources within community organizations.

Conclusions: Inter-organizational collaboration between fire-based EMS agencies and community organizations appears to be a promising approach for advancing integrated emergency care within the community. The six identified practical measures may contribute to the long-term sustainability of collaborative models that bridge medical and social care needs in Japanese communities.

目标:日本社区居民正日益面临复杂的健康和社会挑战。基于火灾的紧急医疗服务(EMS)机构正在遇到越来越多的社会弱势个人,并正在成为关键的合作伙伴。然而,关于这种合作在日本社区内的实施和可持续性的证据仍然有限。我们的目的是探索火灾EMS机构与日本长期护理、福利和卫生组织之间组织间合作的积极经验和挑战,以及其可持续性战略。方法:采用半结构化联合访谈法,对日本20家消防急救机构的26名行政救护人员进行访谈。这些参与者是先前具有一线经验的持牌专业人员,目前被分配到负责规划和协调紧急医疗服务的司。他们是有目的地从响应全国调查的火灾EMS机构中挑选出来的。访谈的重点是与长期护理、福利和卫生组织合作的经验、挑战和方法。访谈通过Zoom进行,逐字记录,并使用定性描述方法进行分析。代码是归纳开发的,分为子类别和总类别,并通过成员检查进行验证。结果:与社区组织的合作可以提高EMS的效率和响应能力,加强专业间的合作和相互理解,并通过促进患者转介到相关支持服务,促进EMS的正确使用。主要挑战包括协调角色的模糊性、伙伴组织内部有限的业务能力、专业间理解不足和信息共享不足。为了维持组织间的协作,与会者强调了促进关系建立和相互理解的重要性,建立可持续的组织间协作框架,改善信息共享和分流支持的基础设施,明确火灾紧急医疗服务机构的角色和应对政策,加强跨专业教育,以及在社区组织内确保足够的人力资源。结论:基于火灾的EMS机构和社区组织之间的组织间合作似乎是促进社区内综合急救护理的一种有希望的方法。确定的六项实际措施可能有助于长期可持续性的协作模式,以满足日本社区的医疗和社会护理需求。
{"title":"Exploring Positive Experiences, Challenges, and Sustainability Measures in Inter-Organizational Collaboration: A Qualitative Study of Fire-Based Emergency Medical Service Agencies in Japan.","authors":"Keiko Ueno, Chie Teramoto, Junko Saito","doi":"10.1080/10903127.2025.2598562","DOIUrl":"10.1080/10903127.2025.2598562","url":null,"abstract":"<p><strong>Objectives: </strong>Community-dwelling populations in Japan are increasingly experiencing complex health and social challenges. Fire-based emergency medical service (EMS) agencies are encountering a growing number of socially vulnerable individuals and are emerging as key partners. However, evidence regarding the implementation and sustainability of such collaborations within Japanese communities remains limited. We aimed to explore the positive experiences and challenges of inter-organizational collaboration between fire-based EMS agencies and long-term care, welfare, and health organizations in Japan as well as strategies for its sustainability.</p><p><strong>Methods: </strong>Semi-structured and joint interviews were conducted with 26 paramedics in administrative roles from 20 fire-based EMS agencies across Japan. These participants were licensed professionals with prior frontline experience who were currently assigned to divisions responsible for planning and coordinating EMS. They were purposively selected from fire-based EMS agencies that had responded to a nationwide survey. The interviews focused on experiences, challenges, and approaches related to collaboration with long-term care, welfare, and health organizations. Interviews were conducted <i>via</i> Zoom, transcribed verbatim, and analyzed using a qualitative descriptive approach. Codes were developed inductively, grouped into subcategories and overarching categories, and validated through member checking.</p><p><strong>Results: </strong>Collaboration with community organizations was perceived to enhance EMS efficiency and responsiveness, strengthen interprofessional collaboration and mutual understanding, and promote the appropriate use of EMS by facilitating patient referral to relevant support services. Key challenges included ambiguity in coordination roles, limited operational capacity within partner organizations, insufficient interprofessional understanding, and inadequate information sharing. To sustain inter-organizational collaboration, participants emphasized the importance of promoting relationship building and mutual understanding, establishing sustainable inter-organizational collaboration framework, improving infrastructure for information sharing and triage support, clarifying the roles and response policies of fire-based EMS agencies, enhancing interprofessional education, and securing adequate human resources within community organizations.</p><p><strong>Conclusions: </strong>Inter-organizational collaboration between fire-based EMS agencies and community organizations appears to be a promising approach for advancing integrated emergency care within the community. The six identified practical measures may contribute to the long-term sustainability of collaborative models that bridge medical and social care needs in Japanese communities.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-11"},"PeriodicalIF":2.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145708993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prehospital Blood Collection for High Sensitivity Cardiac Troponin Measurement in Patients with Acute Chest Pain. 院前采血检测急性胸痛患者高灵敏度心肌肌钙蛋白。
IF 2 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2026-03-05 DOI: 10.1080/10903127.2026.2627353
Michael W Supples, Anna C Snavely, Molly R Ehrig, Nicklaus P Ashburn, Christian John Hunter, Laurel Jackson, Jason P Stopyra, Simon A Mahler

Objectives: High sensitivity cardiac troponin (hs-cTn) measures are used in the emergency department (ED) to evaluate patients with acute chest pain. Prehospital hs-cTn measurement could facilitate earlier rule-out of myocardial infarction (MI). The objective of this study is to assess the performance of prehospital blood draw for hs-cTnI measure alone, in combination with hs-cTnI measured at ED arrival, and incorporating the Myocardial Ischemic Injury Index (MI3) machine learning algorithm to rule-out index MI.

Methods: We conducted a pilot prospective observational cohort study among adult emergency medical services (EMS) patients with acute, non-traumatic chest pain. Two third-service EMS agencies and two tertiary care EDs in North Carolina participated. Demographics and initial ECG findings were collected. Blood was obtained prehospital and on ED arrival for hs-cTnI measurement. The clinical outcome was adjudicated index visit MI. Efficacy (percentage of patients with index MI ruled-out) and negative predictive value (NPV) for index MI were determined for the following strategies: (1) a very-low single prehospital hs-cTnI, (2) serial hs-cTnI change (delta) at the prehospital and arrival timepoints, (3) MI3 incorporating prehospital hs-cTnI alone, and (4) MI3 incorporating prehospital and arrival hs-cTnI.

Results: Of the 75 patients enrolled, 53.3% (40/75) were women, 32.0% (24/75) were Black patients, and the mean age was 62.2 ± 15.7 years. Index MI occurred in 8.0% (6/75). Prehospital hs-cTnI below the limit of quantification (≤2.7 ng/L) had an efficacy of 46.7% (35/75) with an NPV of 100% (95%CI 90.0%-100%) for index MI. A prehospital and arrival hs-cTnI delta ≤3 had an efficacy of 84.3% (43/51) with an NPV of 97.7% (95%CI 87.7-99.9%) for index MI. The standard low-risk MI3 threshold <1.6 with a single prehospital hs-cTnI had an efficacy and NPV for index MI of 76.0% (57/75) and 96.5% (95%CI 87.9-99.6), respectively. Finally, the standard low-risk MI3 threshold incorporating both prehospital and arrival hs-cTnI had an efficacy of 70.6% (36/51) and NPV of 100% (95%CI 90.3-100%) for index MI.

Conclusions: Strategies using prehospital blood for hs-cTnI measurement alone and MI3 with prehospital and arrival hs-cTnI safely identified a large percentage of patients for rule-out, warranting further investigation in a larger trial.

目的:高灵敏度心肌肌钙蛋白(hs-cTn)测量在急诊科(ED)用于评估急性胸痛患者。院前hs-cTn检测有助于早期排除心肌梗死(MI)。本研究的目的是评估院前抽血单独测量hs-cTnI的性能,结合ED到达时测量hs-cTnI,并结合心肌缺血损伤指数(MI3)机器学习算法来排除mi指数。方法:我们在患有急性非创伤性胸痛的成人急诊医疗服务(EMS)患者中进行了一项前瞻性前瞻性观察队列研究。北卡罗来纳州的两家三级服务EMS机构和两家三级护理急诊室参与了研究。收集了人口统计学和初始心电图结果。院前和ED到达时取血测定hs-cTnI。通过以下策略确定了MI的疗效(排除MI指数的患者百分比)和MI指数的阴性预测值(NPV): 1)单个院前hs-cTnI非常低,2)院前和到达时hs-cTnI连续变化(delta), 3) MI3合并院前hs-cTnI单独,4)MI3合并院前和到达时hs-cTnI。结果:入选的75例患者中,女性占53.3%(40/75),黑人占32.0%(24/75),平均年龄为62.2±15.7岁。指数MI发生率为8.0%(6/75)。院前hs-cTnI低于定量限(≤2.7ng/L)对MI指数的疗效为46.7% (35/75),NPV为100% (95%CI 90.0% ~ 100%),院前和到院hs-cTnI δ≤3对MI指数的疗效为84.3% (43/51),NPV为97.7% (95%CI 87.7 ~ 99.9%),结合院前和到院hs-cTnI的标准低危MI3阈值3对MI指数的疗效为70.6% (36/51),NPV为100% (95%CI 90.3 ~ 100%)。采用院前血液单独测定hs-cTnI和院前及入院时使用MI3测定hs-cTnI的策略安全地确定了很大比例的排除患者,这需要在更大规模的试验中进一步研究。
{"title":"Prehospital Blood Collection for High Sensitivity Cardiac Troponin Measurement in Patients with Acute Chest Pain.","authors":"Michael W Supples, Anna C Snavely, Molly R Ehrig, Nicklaus P Ashburn, Christian John Hunter, Laurel Jackson, Jason P Stopyra, Simon A Mahler","doi":"10.1080/10903127.2026.2627353","DOIUrl":"10.1080/10903127.2026.2627353","url":null,"abstract":"<p><strong>Objectives: </strong>High sensitivity cardiac troponin (hs-cTn) measures are used in the emergency department (ED) to evaluate patients with acute chest pain. Prehospital hs-cTn measurement could facilitate earlier rule-out of myocardial infarction (MI). The objective of this study is to assess the performance of prehospital blood draw for hs-cTnI measure alone, in combination with hs-cTnI measured at ED arrival, and incorporating the Myocardial Ischemic Injury Index (MI<sup>3</sup>) machine learning algorithm to rule-out index MI.</p><p><strong>Methods: </strong>We conducted a pilot prospective observational cohort study among adult emergency medical services (EMS) patients with acute, non-traumatic chest pain. Two third-service EMS agencies and two tertiary care EDs in North Carolina participated. Demographics and initial ECG findings were collected. Blood was obtained prehospital and on ED arrival for hs-cTnI measurement. The clinical outcome was adjudicated index visit MI. Efficacy (percentage of patients with index MI ruled-out) and negative predictive value (NPV) for index MI were determined for the following strategies: (1) a very-low single prehospital hs-cTnI, (2) serial hs-cTnI change (delta) at the prehospital and arrival timepoints, (3) MI<sup>3</sup> incorporating prehospital hs-cTnI alone, and (4) MI<sup>3</sup> incorporating prehospital and arrival hs-cTnI.</p><p><strong>Results: </strong>Of the 75 patients enrolled, 53.3% (40/75) were women, 32.0% (24/75) were Black patients, and the mean age was 62.2 ± 15.7 years. Index MI occurred in 8.0% (6/75). Prehospital hs-cTnI below the limit of quantification (≤2.7 ng/L) had an efficacy of 46.7% (35/75) with an NPV of 100% (95%CI 90.0%-100%) for index MI. A prehospital and arrival hs-cTnI delta ≤3 had an efficacy of 84.3% (43/51) with an NPV of 97.7% (95%CI 87.7-99.9%) for index MI. The standard low-risk MI<sup>3</sup> threshold <1.6 with a single prehospital hs-cTnI had an efficacy and NPV for index MI of 76.0% (57/75) and 96.5% (95%CI 87.9-99.6), respectively. Finally, the standard low-risk MI<sup>3</sup> threshold incorporating both prehospital and arrival hs-cTnI had an efficacy of 70.6% (36/51) and NPV of 100% (95%CI 90.3-100%) for index MI.</p><p><strong>Conclusions: </strong>Strategies using prehospital blood for hs-cTnI measurement alone and MI<sup>3</sup> with prehospital and arrival hs-cTnI safely identified a large percentage of patients for rule-out, warranting further investigation in a larger trial.</p>","PeriodicalId":20336,"journal":{"name":"Prehospital Emergency Care","volume":" ","pages":"1-5"},"PeriodicalIF":2.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Prehospital Emergency Care
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