Polish medical sciences and history bulletin最新文献

In the light of a retrospective analysis of 213 case records of infants with urinary tract infections, hyperbilirubinemia was disclosed in 19 cases. In 7 cases jaundice was the main cause of admission of these children to the hospital. It was observed mainly in the youngest age group up to 3 months. Jaundice was hemolytic in some cases and hepatic in others. Urinary tract malformations had no effect on the frequency of jaundice in urinary tract infection or on its intensity.

In the years 1950--1974 53 cases of hiatus hernia were treated surgically at the Department I of Surgery, Institute of Surgery, Medical Academy in Poznan. These included 32 sliding hernias, 16 paraesophageal, 2 mixed, 1 with acquired short esophagus and 2 with congenital short esophagus. In 17 cases the approach was through the chest, in 35 through the abdominal cavity and in 1 through the chest and abdominal cavity. Late results were favorable.

The authors discuss 334 patients operated upon for congenital deformities of the chest. The clinical manifestations, radiological and electrocardiographic investigations and spirometric measurements as well as postoperative complications are described. The results of follow-up examinations in a part of this material are reported.

Lecyvit POLFA was applied in 114 persons as a roborant drug. Satisfactory results of treatment were observed in 106 subjects (93%). Clinical improvement consisted in increased physical and mental activities, better appetite and gain of body weight.

The blood levels of glucagon, growth hormone and glucose were investigated in early (1st day) and late stages (3rd week) of myocardial infarction in 11 cases of severe and 6 cases of mild myocardial infarction. The results were related to those in 9 healthy controls. In severe myocardial infarction associated with complications the glucagon level was statistically significantly higher than in controls in the early as well as in the late stage of the disease. In mild myocardial infarction this was not observed. The growth hormone level was significantly higher than normal in patients with severe myocardial infarction in only a few cases and only in the early stage. The differences between both stages of infarction and between patients and controls were not significant. Blood glucose level in the early stage of severe myocardial infarction was higher than normal and statistically significantly higher than in the late stage. In view of the differences in blood glucose and glucogon levels during severe myocardial infarction it seems that hyperglycemia in early stages of the disease depends on the high catecholamines level in the blood and on the insulin: glucagon index and not on the absolute concentration of glucagon in the blood.

Three cases of adenomatoid tumor of the uterus in women aged 30, 40 and 49 years, and three cases of the tumor situated in the oviducts in women aged 39, 43 and 50 years were analyzed micro- and macroscopically. A tubulo-canalicular, a microcystic and a mixed form were distinguished. Inflammatory changes in the oviducts, myomas and myomatosis of the uterus seem to be conducive to growth of adenomatoid tumor. The authors emphasize the diversity of microscopic structure, creating difficulties of differential diagnosis. Some histochemical reactions may be useful in diagnosis.

Renal injury and regeneration was followed light--and electron microscopically in rabbits treated with uranyl nitrate. The presence and importance of glomerular lesions is noteworthy.

The analyzed material included 60 children aged 5--16 years with the diagnosis of simple obesity. It was found that 30% of them, nearly all girls, had obese parents. This may suggest an increased tendency for familial occurence of obesity in girls. The birth weight of obese children was usually higher than that of children with normal body weight, and 36,6% of children began to show overweight before the age of 3 years. It was found that the index of slender body builds is much lower in obese children than in controls. The analysis demonstrated also that 28.9% of obese children were more or less retarded mentally which may be also a pathogenetic factor in obesity.

In patients with rheumatoid arthritis and in healthy controls a continuous rise in acid phosphatase activity was observed in PHA-stimulated lymphocytes and the activity index was higher in patients than in controls. Differences were also observed between these groups in the activity of nonspecific esterase, beta-glucuronidase, and glycogen content at different hours of culture.

Rats kept on a low-magnesium diet for 14 weeks developed increasing clinical symptoms, from slight trophic changes to inhibition of growth. Focal fragmentation of myocardial fibers was followed by focal fuchsinophilia and later--by focal necrosis. Increasing morphological lesions were associated with calcium salts deposition in the degenerated myocardial fibers, connective tissue and wall of cardiac blood vessels. The low-magnesium diet did not affect the activity of ATP-ases and cytochrome oxidase. The areas of myocardial degeneration and necrosis were free of the activity of alkaline phosphatase and succinic dehydrogenase.