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Social determinants of health and COVID-19 recovery after inpatient rehabilitation. 健康的社会决定因素与 COVID-19 住院康复后的恢复。
IF 4.6 4区 医学 Q1 REHABILITATION Pub Date : 2024-09-01 Epub Date: 2024-03-23 DOI: 10.1002/pmrj.13141
Hannah Martin, Christopher Lewis, Sean Dreyer, Juliana Couri, Sanchita Sen, Prakash Jayabalan

Background: Neighborhoods with more social determinants of health (SDOH) risk factors have higher rates of infectivity, morbidity, and mortality from COVID-19. Patients with severe COVID-19 infection can have long-term functional deficits leading to lower quality of life (QoL) and independence measures. Research shows that these patients benefit greatly from inpatient rehabilitation facilities (IRF) admission, but there remains a lack of studies investigating long-term benefits of rehabilitation once patients are returned to their home environment.

Objective: To determine SDOH factors related to long-term independence and QoL of COVID-19 patients after IRF stay.

Design: Multisite cross-sectional survey.

Setting: Two urban IRFs.

Main outcome measures: Primary outcome measures were Post-COVID Functional Status Scale (PCFS) and Short Form-36 (SF-36) scores. Secondary outcomes were quality indicator (QI) scores while at IRF and a health care access questionnaire. Results were analyzed using analysis of variance and multivariate logistic regression analyses.

Results: Participants (n = 48) who were greater than 1 year post-IRF stay for severe COVID-19 were enrolled in the study. Higher SF-36 scores were associated with male gender (p = .002), higher income (≥$70,000, p = .004), and living in the city (p = .046). Similarly, patients who were of the male gender (p = .004) and had higher income (≥$70,000, p = .04) had a greater odds of a 0 or 1 on the PCFS. Age was not associated with differences. Women were more likely to seek follow-up care (p = .014). Those who sought follow-up care reported lower SF-36 overall and emotional wellness scores, p = .041 and p = .007, respectively. Commonly reported barriers to health care access were financial and time constraints.

Conclusions: Patients with SDOH risk factors need to be supported in the outpatient setting to maintain functional gains made during IRF stays. Female gender, income, and urban setting are potential predictors for long-term QoL and independence deficits after rehabilitation for COVID-19 infection. Low emotional wellness is an indicator for patients to seek out care as far out as 1 year from their rehabilitation stay.

背景:健康的社会决定因素(SDOH)风险因素较多的社区,COVID-19 的感染率、发病率和死亡率都较高。严重感染 COVID-19 的患者会出现长期功能障碍,导致生活质量(QoL)和独立性降低。研究表明,这些患者从入住住院康复设施(IRF)中获益匪浅,但目前仍缺乏对患者返回家庭环境后康复的长期益处的研究:目的:确定与COVID-19患者在IRF住院后的长期独立性和QoL相关的SDOH因素:设计:多地点横断面调查:主要结果测量:主要结果指标:主要结果指标为COVID后功能状态量表(PCFS)和SF-36短表(SF-36)评分。次要结果为在IRF期间的质量指标(QI)得分和医疗服务获取情况问卷。结果采用方差分析和多变量逻辑回归分析进行分析:因重症 COVID-19 在 IRF 住院超过 1 年的参与者(n = 48)参加了研究。SF-36 评分较高与男性(p = .002)、收入较高(≥ 70,000 美元,p = .004)和居住在城市(p = .046)有关。同样,男性(p = .004)和收入较高(≥70,000 美元,p = .04)的患者在 PCFS 中得 0 分或 1 分的几率更大。年龄与差异无关。女性更有可能寻求后续治疗(p = .014)。寻求后续治疗者的 SF-36 总分和情绪健康得分较低,分别为 p = .041 和 p = .007。普遍报告的获得医疗服务的障碍是经济和时间限制:结论:具有 SDOH 风险因素的患者需要在门诊环境中得到支持,以保持在 IRF 住院期间获得的功能收益。女性性别、收入和城市环境是预测COVID-19感染康复后长期生活质量和独立性缺陷的潜在因素。情绪低落是患者在康复住院一年后寻求护理的一个指标。
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引用次数: 0
Postinjection protocols following platelet-rich plasma administration for knee osteoarthritis: A systematic review. 富血小板血浆治疗膝骨关节炎后的注射方案:系统综述。
IF 4.6 4区 医学 Q1 REHABILITATION Pub Date : 2024-09-01 Epub Date: 2024-03-25 DOI: 10.1002/pmrj.13139
Oscar Paul Levine, Koushik Kondapi, Vehniah Kristin Tjong, Chetan Gohal

Objective: Platelet-rich plasma (PRP) use in treating orthopedic conditions has increased, yet evidence of its clinical efficacy is inconsistent and limited by heterogeneity in osteoarthritis (OA) severity, PRP preparations and protocols, and clinical outcome measurement. This review aims to characterize the variations in postinjection protocols in studies assessing the clinical efficacy of PRP for knee OA.

Literature survey: A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A literature search from database inception to February 2023 of CINAHL, MEDLINE, and EMBASE was conducted.

Methodology: Article screening, data extraction, and risk of bias assessments were completed in duplicate by two reviewers. Primary outcomes were presence/absence and timing of the following postinjection protocol components: nonsteroidal anti-inflammatory drug (NSAID) restrictions, non-NSAID analgesic and cryotherapy use, immediate knee flexion/extension, immediate rest, activity restriction, return-to-activity guidelines, and rehabilitation protocols. A descriptive analysis was used to analyze the data. Given study heterogeneity, a meta-analysis was not performed.

Synthesis: A total of 187 studies were included for analysis. Half of all studies (51.9%) excluded patients due to preinjection NSAID use, most often within 5 days of blood sampling or injection. Postinjection NSAID restriction was included in 42.8% of studies, ranging from 1 to 1800 days. Few studies (19.4%) that permitted non-NSAID analgesia restricted their use prior to clinical assessments. Postinjection immediate flexion, extension, and immobilization were rarely (8.6%) mentioned. Activity restriction was included in a third of studies (35.3%), with the most frequent length of restriction being 1 day. Postinjection return-to-activity protocols were less common (20.3%), usually with a "gradual" and/or "as tolerated" recommendation. A minority of studies (16.0%) reported physical therapy protocols and the vast majority (93.3%) were home based.

Conclusion: Significant heterogeneity remains in post-PRP injection protocols, with unclear consensus regarding optimal recommendations and limited rationale for the protocols outlined. Further study is necessary to compare protocols directly and to determine which pre- and postinjection recommendations can result in optimal outcomes.

目的:富血小板血浆(PRP)在骨科疾病治疗中的应用日益增多,但其临床疗效的证据并不一致,且受限于骨关节炎(OA)严重程度、PRP制剂和方案以及临床结果测量的异质性。本综述旨在描述在评估 PRP 对膝关节 OA 临床疗效的研究中注射后方案的差异:根据《系统综述和元分析首选报告项目》指南进行了系统综述。文献检索时间从数据库建立之初至 2023 年 2 月,检索范围包括 CINAHL、MEDLINE 和 EMBASE:文章筛选、数据提取和偏倚风险评估由两名审稿人重复完成。主要研究结果为注射后方案中是否包含以下内容以及时间安排:非甾体类抗炎药(NSAID)限制、非NSAID镇痛药和冷冻疗法的使用、立即屈伸膝关节、立即休息、活动限制、恢复活动指南和康复方案。数据分析采用描述性分析方法。鉴于研究的异质性,未进行荟萃分析:共纳入 187 项研究进行分析。半数研究(51.9%)排除了注射前使用非甾体抗炎药的患者,最常见的情况是在抽血或注射后 5 天内使用非甾体抗炎药。42.8%的研究纳入了注射后非甾体抗炎药限制,时间从1天到1800天不等。很少有研究(19.4%)允许在临床评估前限制使用非甾体抗炎镇痛药。很少(8.6%)提到注射后立即屈伸和固定。三分之一的研究(35.3%)提到了活动限制,最常见的限制时间为 1 天。注射后恢复活动的方案较少(20.3%),通常建议 "循序渐进 "和/或 "根据耐受情况"。少数研究(16.0%)报告了物理治疗方案,绝大多数研究(93.3%)以家庭为基础:结论:PRP 注射后的治疗方案仍存在很大的异质性,对最佳建议的共识不明确,概述的治疗方案的合理性有限。有必要开展进一步研究,以直接比较各种方案,并确定哪些注射前和注射后建议可带来最佳疗效。
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引用次数: 0
Cervical polyradiculopathy after varicella zoster virus reactivation. 水痘带状疱疹病毒再激活后的颈椎多发性神经病。
IF 4.6 4区 医学 Q1 REHABILITATION Pub Date : 2024-09-01 Epub Date: 2024-02-16 DOI: 10.1002/pmrj.13124
Edmond Benedetti, Rebecca Liu, Steven Gershon
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引用次数: 0
Assessing the risk of lumbar degenerative disc disease associated with swimming: A systematic review. 评估与游泳有关的腰椎间盘退行性病变风险:系统综述。
IF 4.6 4区 医学 Q1 REHABILITATION Pub Date : 2024-09-01 Epub Date: 2024-03-19 DOI: 10.1002/pmrj.13138
Connie Hsu, Timothy Genovese, Kelly C McInnis

Objective: The purpose of the current study is to synthesize the outcomes of investigations reporting the odds of lumbar degenerative disc disease (DDD) in competitive swimmers compared to controls.

Literature survey: PubMed, Embase, and Web of Science databases were searched according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines from inception until March 2023 to identify relevant studies evaluating the risk for lumbar DDD associated with swimming.

Methods: Data in the current literature were synthesized for positive imaging findings of DDD at one or more lumbar level in swimmers compared to nonswimmers. Additionally, data regarding prevalence of lumbar disc degeneration and back pain in competitive swimmers were synthesized.

Synthesis: Four studies were included in the final analysis. Study quality and risk of bias were deemed adequate. There was significant heterogeneity among studies (I2 = 0.74) regarding data collected, population of swimmers, sample size, and methods. Therefore, a meta-analysis was not conducted. Three of the four studies included in this review reported that swimmers have increased odds of developing lumbar DDD. Additionally, secondary outcome analysis indicated that swimmers have a higher probability of developing moderate-to-severe back pain.

Conclusion: Competitive swimming appears to be associated with the presence of DDD on advanced imaging and moderate-to-severe back pain. These findings are limited by significant differences in study methodology in the included studies. Although swimming is conventionally considered a low-impact sport, elite swimmers risk developing lower back pain and disc pathology, possibly because training involves unique biomechanics with repetitive rotational and hyperextension/flexion of the spine. Further research investigating risk factors involving biomechanics of swimming on the spine may have important implications for stroke technique, injury prevention, and rehabilitation for swimmers.

目的:本研究的目的是综合报告竞技游泳运动员与对照组相比患腰椎间盘退行性病变(DDD)几率的调查结果:根据《系统综述和元分析首选报告项目》(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)指南,检索了从开始到2023年3月的PubMed、Embase和Web of Science数据库,以确定评估与游泳相关的腰椎间盘退行性病变风险的相关研究:方法:综合现有文献中关于游泳者与非游泳者一个或多个腰椎水平 DDD 的阳性成像结果的数据。此外,还综合了有关竞技游泳运动员腰椎间盘变性和背痛患病率的数据:最终分析包括四项研究。研究质量和偏倚风险被认为是适当的。在收集的数据、游泳运动员人群、样本大小和方法方面,各研究之间存在明显的异质性(I2 = 0.74)。因此,没有进行荟萃分析。本研究纳入的大多数研究(四项研究中的三项)都报告称,游泳者患腰椎间盘突出症的几率增加。此外,次要结果分析表明,游泳运动员患中度至重度背痛的几率更高:结论:竞技游泳似乎与高级成像显示的腰椎间盘突出症和中重度背痛有关。由于所纳入研究的研究方法存在显著差异,这些发现受到了限制。虽然游泳在传统上被认为是一项低冲击运动,但精英游泳运动员仍有可能患上下背痛和椎间盘病变,这可能是因为训练涉及独特的生物力学,脊柱会反复旋转和过度伸展/屈曲。进一步研究游泳生物力学对脊柱影响的风险因素,可能会对游泳运动员的划水技术、损伤预防和康复产生重要影响。
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引用次数: 0
Answering the Rehabilitation 2030 Call. 响应 2030 年的康复号召。
IF 2.2 4区 医学 Q1 REHABILITATION Pub Date : 2024-09-01 Epub Date: 2024-03-28 DOI: 10.1002/pmrj.13160
Emily Hillaker, Michael Bova, Jina Libby, Maria Tricarico, Patrick Andrews, Rebecca Scharf

In 2017, the World Health Organization initiated a global effort to improve rehabilitative services by 2030, with the overall goal of helping individuals with disabilities achieve maximal independence and improved well-being. Though more than 1 billion people worldwide live with a disability, a significant portion do not have access to appropriate rehabilitative services. In low-income countries, such as Zambia, where rehabilitative services are greatly lacking, disability can further exacerbate economic disparities in the context of personal, cultural, and environmental factors that limit participation in society. Therefore, expansion of rehabilitative services in low-income countries is a pressing global need, and such efforts must be tailored to the societal and cultural framework in which they are implemented. Community-based rehabilitation programs are uniquely poised to provide services in similar low-to-middle-income countries as they eliminate travel barriers to care, allow for regular follow-up, and address the societal determinants of disability by encouraging greater community engagement and by decreasing cultural stigma around disability. Special Hope Network (SHN), a community-based rehabilitation organization in Lusaka, Zambia that serves families caring for children with physical and cognitive disabilities, represents a cost-effective, sustainable, and culturally practical model to provide rehabilitative care. We propose this organization's model as one that can be reproduced and expanded upon in other low-to-middle-income countries to answer the World Health Organization's call to action.

2017 年,世界卫生组织发起了一项到 2030 年改善康复服务的全球努力,其总体目标是帮助残疾人实现最大程度的自立和改善福祉。虽然全球有超过 10 亿人患有残疾,但其中很大一部分人无法获得适当的康复服务。在赞比亚等低收入国家,康复服务非常缺乏,在个人、文化和环境因素限制参与社会的背景下,残疾会进一步加剧经济差距。因此,在低收入国家扩大康复服务是一项紧迫的全球需求,而这些努力必须适合其实施的社会和文化框架。以社区为基础的康复计划在类似的中低收入国家提供服务方面具有得天独厚的优势,因为这些计划消除了获得护理的旅行障碍,允许定期随访,并通过鼓励更多的社区参与和减少对残疾的文化羞辱来解决残疾的社会决定因素。特殊希望网络(SHN)是赞比亚卢萨卡的一家社区康复机构,主要为照顾有身体和认知障碍儿童的家庭提供服务,是一种具有成本效益、可持续发展和文化实用性的康复护理模式。我们建议在其他中低收入国家复制和推广该组织的模式,以响应世界卫生组织的行动号召。
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引用次数: 0
Lipohemarthrosis in the detection of intraarticular fractures: Looking beyond the tibial plateau. 检测关节内骨折中的脂肪性关节病:超越胫骨平台。
IF 4.6 4区 医学 Q1 REHABILITATION Pub Date : 2024-09-01 Epub Date: 2024-07-10 DOI: 10.1002/pmrj.13220
Jack Porrino, Colby Shreve, Eric Marten, Hyojeong Lee, Andrew Haims
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引用次数: 0
Impact of the COVID-19 pandemic on the rate of lower limb amputation in Veterans. COVID-19 大流行对退伍军人下肢截肢率的影响。
IF 4.6 4区 医学 Q1 REHABILITATION Pub Date : 2024-09-01 Epub Date: 2024-03-14 DOI: 10.1002/pmrj.13130
Kierra J Falbo, Nicole R Walker, Amber L Wacek, Juan E Cave, Matthew D Sauerbrey, Amy A Gravely, Mary E Matsumoto, John M Looft

Background: The COVID-19 pandemic led to changes in health care, including postponement of nonurgent appointments. These changes, combined with overall decreased activity levels, may have placed individuals with vascular disease at increased risk for skin ulceration and amputation.

Objective: To determine the rates of lower limb amputation in Veterans due to complications of diabetes and/or vascular disease in the year following onset of the COVID-19 pandemic (March 2020-March 2021) compared to the previous 3 years (March 2017-March 2020).

Design: Retrospective chart review.

Setting: Minneapolis Veterans Affairs Health Care System.

Participants: Veterans with a vascular consult appointment note between March 1, 2017, and February 28, 2021.

Interventions: Not applicable.

Main outcome measures: Primary outcome was lower limb amputation rate in the year following onset of the COVID-19 pandemic compared to the previous 3 years. Secondary outcome was the rate of lower limb wounds in the same time frame. We hypothesized that rates of lower limb amputation and wounds increased during the pandemic.

Results: Vascular consult appointments (n = 4183) were reviewed between March 1, 2017, and February 28, 2021. Significantly higher rates of amputation (7.52% vs. 5.19%; p = .006) and wound presence (16.77% vs. 11.66%; p < .001) were found 1 year postpandemic compared to the previous 3 years. Amputation and wound rates did not significantly increase between pairs of consecutive years prior to the pandemic but significantly increased between the year preceding the pandemic and the first year of the pandemic (amputation p = .047; wound p = .004).

Conclusions: Increased rates of amputation and wounds in Veterans following the onset of the COVID-19 pandemic are likely due to disruption of care, lifestyle changes, and other pandemic-related factors. Awareness of COVID-19-related negative health effects is imperative for health care providers to ensure appropriate allocation of resources and alternate models for care delivery for amputation and preventative care as part of disaster response.

背景:COVID-19 大流行导致了医疗保健方面的变化,包括推迟非急诊预约。这些变化,再加上整体活动量的减少,可能会增加血管疾病患者皮肤溃疡和截肢的风险:与前三年(2017 年 3 月至 2020 年 3 月)相比,确定 COVID-19 大流行发生后一年(2020 年 3 月至 2021 年 3 月)退伍军人因糖尿病和/或血管疾病并发症而导致下肢截肢的比例:设计:回顾性病历审查:明尼阿波利斯退伍军人事务医疗保健系统:干预措施:不适用:不适用:主要结果:COVID-19大流行后一年内的下肢截肢率与前三年相比。次要结果是同一时期的下肢创伤率。我们假设在大流行期间,下肢截肢率和伤口率都会增加:我们对 2017 年 3 月 1 日至 2021 年 2 月 28 日期间的血管咨询预约(n = 4183)进行了审查。截肢率(7.52% vs. 5.19%; p = .006)和伤口出现率(16.77% vs. 11.66%; p 结论:大流行期间,下肢截肢率和伤口出现率显著增加:COVID-19 大流行后,退伍军人的截肢率和伤口率上升可能是由于护理中断、生活方式改变以及其他与大流行相关的因素造成的。医疗服务提供者必须认识到 COVID-19 对健康的负面影响,以确保适当的资源分配以及截肢和预防性护理的替代护理模式,并将其作为灾难响应的一部分。
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引用次数: 0
Comparing apples to oranges: Bringing basic physics to the bedside. 苹果与橘子的比较:将基础物理学应用于临床
IF 4.6 4区 医学 Q1 REHABILITATION Pub Date : 2024-09-01 Epub Date: 2024-02-28 DOI: 10.1002/pmrj.13135
Sammy Wu, Kristen De Vries, Iñigo San Millán, Grigory Syrkin
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引用次数: 0
A systematic review and meta-analysis of Nordic walking for chronic heart failure with low left ventricular ejection fraction. 北欧式健走治疗左心室射血分数低的慢性心力衰竭的系统回顾和荟萃分析。
IF 2.2 4区 医学 Q1 REHABILITATION Pub Date : 2024-08-31 DOI: 10.1002/pmrj.13254
Aulia Syavitri Dhamayanti, Rahmad Rahmad, Samiah Rachmawati, Yoga Waranugraha

Background: Nordic walking (NW) has been reported to be beneficial in various chronic diseases.

Objective: To determine whether NW improves function in patients with heart failure (HF) with low left ventricular ejection fraction more than conventional cardiac rehabilitation or usual care.

Methods: Systematic literature searches in PubMed, ScienceDirect, and Web of Science were conducted. According to patient, intervention, comparison, and outcome (PICO) principles, a stepwise selection process was completed to identify eligible studies. Only randomized controlled trials (RCTs) were included in this systematic review and meta-analysis. Pooled effects were determined using a random effect analysis model for the meta-analysis.

Results: A total of 282 participants from four RCTs were included. The improvement of peak oxygen consumption (peak VO2) was greater in the NW group than in the control group (mean difference [MD] = 2.18 mL/kg/min; 95% confidence interval [CI] = 1.35-3.01; p < .01). The improvement of the 6-minute walk test (6MWT) distance was also greater in the NW group than in the control group (MD = 16.51 meters; 95% CI = 3.23-29.80; p = .01).

Conclusion: This systematic review highlights the benefits of NW training in patients with chronic HF, particularly those with systolic dysfunction. Specifically, NW walking was associated with increased peak VO2 and 6MWT improvement compared to conventional cardiac rehabilitation or usual care. These results suggest that NW may be a useful component of cardiac rehabilitation. However, additional larger studies with a wider range of patients are needed.

背景:据报道,北欧式行走(NW)对多种慢性疾病有益:据报道,北欧式行走(NW)对多种慢性疾病有益:目的:确定北欧式行走对左心室射血分数低的心力衰竭(HF)患者的功能改善是否优于传统的心脏康复或常规护理:方法:在 PubMed、ScienceDirect 和 Web of Science 中进行了系统的文献检索。根据患者、干预、比较和结果(PICO)原则,完成了逐步筛选过程,以确定符合条件的研究。本系统综述和荟萃分析只纳入了随机对照试验(RCT)。荟萃分析采用随机效应分析模型确定汇总效应:结果:共纳入了四项研究中的 282 名参与者。NW组的峰值耗氧量(peak VO2)改善幅度大于对照组(平均差异[MD] = 2.18 mL/kg/min;95%置信区间[CI] = 1.35-3.01;P 结论:这篇系统综述强调了NW疗法的益处:本系统综述强调了负重行走训练对慢性心房颤动患者,尤其是收缩功能障碍患者的益处。具体而言,与传统的心脏康复或常规护理相比,NW 步行与峰值 VO2 的增加和 6MWT 的改善相关。这些结果表明,负重行走可能是心脏康复的一个有用组成部分。不过,还需要对更多患者进行更大规模的研究。
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引用次数: 0
Peripheral neuropathy prevalence and effect on mobility 12 months after prosthesis prescription among individuals with dysvascular lower extremity amputation. 周围神经病变的发病率和对下肢截肢者安装假肢 12 个月后活动能力的影响。
IF 2.2 4区 医学 Q1 REHABILITATION Pub Date : 2024-08-29 DOI: 10.1002/pmrj.13253
Daniel C Norvell, Elizabeth G Halsne, Alison W Henderson, Aaron P Turner, Wayne T Biggs, Joseph Webster, Joseph M Czerniecki, David C Morgenroth

Objective: To determine the prevalence of peripheral neuropathy (PN) and its effect on mobility in patients who were prescribed a lower limb prosthesis (LLP) after an incident dysvascular transtibial (TT) or transfemoral (TF) lower extremity amputation (LEA). We also sought to determine if the effect of PN on mobility was modified by amputation level or depression.

Design: Participants were identified retrospectively through the Veterans Affairs (VA) Corporate Data Warehouse (CDW) from March 1, 2018, to November 30, 2020, then were contacted prospectively to obtain their self-reported mobility. Multiple logistic regression was used to control for potential confounders and identify potential effect modifiers.

Setting: The VA CDW, the National Prosthetics Patient Database, participant mailings and phone calls.

Participants: Three hundred fifty-seven individuals who underwent a TT or TF amputation due to diabetes and/or peripheral arterial disease and were fitted with a qualifying LLP.

Interventions: Not applicable.

Main outcomes measures: The Locomotor Capabilities Index basic and advanced mobility subscale scores.

Results: Two-hundred thirty seven participants (66%) had a diagnosis of PN prior to prosthesis prescription. The detrimental effect of PN on achieving basic and advanced mobility was significant after adjusting for potential confounding factors (adjusted odds ratio [aOR], 0.53; 95% confidence interval [CI], 0.30-0.94; p = .03 and aOR, 0.43; 95% CI, 0.24-0.77; p = .005, respectively). The detrimental effect of PN was more pronounced in patients with depression, especially for advanced mobility (aOR, 0.36; 95% CI, 0.14-0.95; p = .04) versus no depression (aOR, 0.53; 95% CI, 0.27-1.0; p = .07).

Conclusions: PN is common in patients who have undergone an LEA due to diabetes and/or vascular disease and patients with this diagnosis should be carefully evaluated. Targeted rehabilitation programs to mitigate its potential detrimental effects on mobility are important and should specifically include mental health assessment and treatment.

目的目的:确定下肢截肢(LEA)患者中周围神经病变(PN)的发病率及其对活动能力的影响。我们还试图确定PN对活动能力的影响是否会因截肢程度或抑郁而改变:设计:我们通过退伍军人事务局(VA)企业数据仓库(CDW)对2018年3月1日至2020年11月30日期间的参与者进行了回顾性识别,然后与他们进行了前瞻性联系,以获得他们自我报告的活动能力。采用多元逻辑回归控制潜在的混杂因素,并确定潜在的效应调节因素:退伍军人社区数据中心、国家假肢患者数据库、参与者邮件和电话:357名因糖尿病和/或外周动脉疾病接受TT或TF截肢手术并安装了合格LLP的患者:主要结果测量:主要结果测量:运动能力指数基础和高级移动能力分量表评分:结果:237名参与者(66%)在安装假肢前被诊断出患有PN。在调整了潜在的混杂因素后,PN对实现基本和高级活动能力的不利影响是显著的(调整后的几率比[aOR]分别为0.53;95%置信区间[CI]为0.30-0.94;p = .03和aOR为0.43;95%置信区间[CI]为0.24-0.77;p = .005)。PN的不利影响在抑郁症患者中更为明显,尤其是晚期行动不便患者(aOR,0.36;95% CI,0.14-0.95;p = .04)与无抑郁症患者(aOR,0.53;95% CI,0.27-1.0;p = .07):结论:PN在因糖尿病和/或血管疾病而接受LEA的患者中很常见,因此应仔细评估有此诊断的患者。有针对性的康复计划对减轻其对行动能力的潜在不利影响非常重要,其中应特别包括心理健康评估和治疗。
{"title":"Peripheral neuropathy prevalence and effect on mobility 12 months after prosthesis prescription among individuals with dysvascular lower extremity amputation.","authors":"Daniel C Norvell, Elizabeth G Halsne, Alison W Henderson, Aaron P Turner, Wayne T Biggs, Joseph Webster, Joseph M Czerniecki, David C Morgenroth","doi":"10.1002/pmrj.13253","DOIUrl":"https://doi.org/10.1002/pmrj.13253","url":null,"abstract":"<p><strong>Objective: </strong>To determine the prevalence of peripheral neuropathy (PN) and its effect on mobility in patients who were prescribed a lower limb prosthesis (LLP) after an incident dysvascular transtibial (TT) or transfemoral (TF) lower extremity amputation (LEA). We also sought to determine if the effect of PN on mobility was modified by amputation level or depression.</p><p><strong>Design: </strong>Participants were identified retrospectively through the Veterans Affairs (VA) Corporate Data Warehouse (CDW) from March 1, 2018, to November 30, 2020, then were contacted prospectively to obtain their self-reported mobility. Multiple logistic regression was used to control for potential confounders and identify potential effect modifiers.</p><p><strong>Setting: </strong>The VA CDW, the National Prosthetics Patient Database, participant mailings and phone calls.</p><p><strong>Participants: </strong>Three hundred fifty-seven individuals who underwent a TT or TF amputation due to diabetes and/or peripheral arterial disease and were fitted with a qualifying LLP.</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcomes measures: </strong>The Locomotor Capabilities Index basic and advanced mobility subscale scores.</p><p><strong>Results: </strong>Two-hundred thirty seven participants (66%) had a diagnosis of PN prior to prosthesis prescription. The detrimental effect of PN on achieving basic and advanced mobility was significant after adjusting for potential confounding factors (adjusted odds ratio [aOR], 0.53; 95% confidence interval [CI], 0.30-0.94; p = .03 and aOR, 0.43; 95% CI, 0.24-0.77; p = .005, respectively). The detrimental effect of PN was more pronounced in patients with depression, especially for advanced mobility (aOR, 0.36; 95% CI, 0.14-0.95; p = .04) versus no depression (aOR, 0.53; 95% CI, 0.27-1.0; p = .07).</p><p><strong>Conclusions: </strong>PN is common in patients who have undergone an LEA due to diabetes and/or vascular disease and patients with this diagnosis should be carefully evaluated. Targeted rehabilitation programs to mitigate its potential detrimental effects on mobility are important and should specifically include mental health assessment and treatment.</p>","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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