首页 > 最新文献

PM&R最新文献

英文 中文
Comparative efficacy and acceptability of different intensity levels of extracorporeal shock wave therapy in adults with plantar heel pain: A systematic review and network meta-analysis. 不同强度体外冲击波治疗成人足底跟痛的比较疗效和可接受性:一项系统综述和网络荟萃分析。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-07-25 DOI: 10.1002/pmrj.13417
Peng Zhao, Yuwei He, Meng Li, Jialin Wang, Ruirui Wang, Xinwen Cui

Objective: To estimate the comparative clinical efficacy and acceptability of different intensity levels of extracorporeal shock wave therapy (ESWT) in adults with plantar heel pain (PHP). TYPE: Systematic review and network meta-analysis.

Literature survey: PubMed, EMBASE, Cochrane Library electronic databases and Web of Science for randomized controlled trials from inception to March 2024.

Methodology: We included placebo-controlled and head-to-head trials of different intensity levels of ESWT used to treat adults with PHP. Data were extracted following a predefined hierarchy. We assessed the studies' risk of bias in according to the Cochrane risk of bias tool, and the certainty of the evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. Primary outcomes were efficacy (success rate) and acceptability (all-course discontinuation rate). Secondary outcomes were pain and function scores changes. All interventions were ranked using the surface under the cumulative ranking curve to determine the hierarchy of treatment.

Synthesis: 22 RCTs comprising 2299 participants met the inclusion criteria. In terms of efficacy, all intensity levels of ESWT were more effective than placebo, with ORs ranging from 2.29 (95% CI 1.39-3.76) for medium intensity ESWT (M-ESWT) to 5.50 (95% CI 1.00-30.29) for low intensity ESWT (L-ESWT). In terms of acceptability, there was no statistically significant difference between all intensity levels of ESWT and placebo, with ORs ranging from 0.83 (0.47-1.45) for M-ESWT to 1.42 (0.19-10.71) for L-ESWT. For pain relief, only M-ESWT and H-ESWT were superior to placebo (SMD -0.60, 95% CI -0.94 to -0.26; SMD -0.28, 95% CI -0.44 to -0.11), whereas there was no difference between them (p = .05). For function improved, there was no statistically significant difference between all intensity levels of ESWT and placebo (range of ORs 1.02-3.44). In contrast, there were no significant differences among the intensity levels in all outcomes. Of the 22 trials, 7 (32%) were assessed as high risk of bias, and the rest (68%) were assessed as unclear risk. The certainty of evidence was low to very low.

Conclusion: Compared to the placebo, all intensity levels of ESWT were more favorable in terms of efficacy, but there was no difference in terms of acceptability. In addition, M-ESWT appeared to provide additional benefits in pain and function for patients with PHP compared to the other intensity levels. The results provide an evidence-based basis for considering ESWT as an alternative for patients with PHP for whom conservative treatment is not effective, and also highlight future research priorities to providing more decision-making for the clinical management of PHP.

目的:评价不同强度体外冲击波治疗(ESWT)治疗成人足底跟痛(PHP)的临床疗效及可接受性。类型:系统综述和网络荟萃分析。文献调查:PubMed, EMBASE, Cochrane图书馆电子数据库和Web of Science从成立到2024年3月的随机对照试验。方法:我们纳入了不同强度ESWT治疗成人PHP的安慰剂对照和头对头试验。数据是按照预定义的层次结构提取的。我们根据Cochrane偏倚风险工具评估研究的偏倚风险,并使用分级建议评估、发展和评估(GRADE)框架评估证据的确定性。主要结局为疗效(成功率)和可接受性(全疗程停药率)。次要结果是疼痛和功能评分的变化。采用累积排序曲线下的曲面对所有干预措施进行排序,以确定治疗等级。综合:22项随机对照试验包括2299名受试者符合纳入标准。就疗效而言,所有强度的ESWT都比安慰剂更有效,中强度M-ESWT (M-ESWT)的or值为2.29 (95% CI 1.39-3.76),低强度ESWT (L-ESWT)的or值为5.50 (95% CI 1.00-30.29)。在可接受性方面,ESWT与安慰剂的所有强度水平之间无统计学差异,M-ESWT的or值为0.83 (0.47-1.45),L-ESWT的or值为1.42(0.19-10.71)。在疼痛缓解方面,只有M-ESWT和H-ESWT优于安慰剂(SMD -0.60, 95% CI -0.94至-0.26;SMD -0.28, 95% CI -0.44至-0.11),而两者之间无差异(p = 0.05)。对于功能改善,ESWT的所有强度水平与安慰剂之间无统计学差异(ORs范围为1.02-3.44)。相比之下,所有结果的强度水平之间没有显著差异。在22项试验中,7项(32%)被评估为高风险,其余(68%)被评估为风险不明确。证据的确定性很低甚至很低。结论:与安慰剂相比,ESWT的所有强度水平在疗效方面更有利,但在可接受性方面没有差异。此外,与其他强度水平相比,M-ESWT似乎为PHP患者提供了额外的疼痛和功能益处。本研究结果为考虑ESWT作为保守治疗无效的PHP患者的替代方案提供了循证依据,也突出了未来的研究重点,为PHP的临床管理提供更多的决策。
{"title":"Comparative efficacy and acceptability of different intensity levels of extracorporeal shock wave therapy in adults with plantar heel pain: A systematic review and network meta-analysis.","authors":"Peng Zhao, Yuwei He, Meng Li, Jialin Wang, Ruirui Wang, Xinwen Cui","doi":"10.1002/pmrj.13417","DOIUrl":"10.1002/pmrj.13417","url":null,"abstract":"<p><strong>Objective: </strong>To estimate the comparative clinical efficacy and acceptability of different intensity levels of extracorporeal shock wave therapy (ESWT) in adults with plantar heel pain (PHP). TYPE: Systematic review and network meta-analysis.</p><p><strong>Literature survey: </strong>PubMed, EMBASE, Cochrane Library electronic databases and Web of Science for randomized controlled trials from inception to March 2024.</p><p><strong>Methodology: </strong>We included placebo-controlled and head-to-head trials of different intensity levels of ESWT used to treat adults with PHP. Data were extracted following a predefined hierarchy. We assessed the studies' risk of bias in according to the Cochrane risk of bias tool, and the certainty of the evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. Primary outcomes were efficacy (success rate) and acceptability (all-course discontinuation rate). Secondary outcomes were pain and function scores changes. All interventions were ranked using the surface under the cumulative ranking curve to determine the hierarchy of treatment.</p><p><strong>Synthesis: </strong>22 RCTs comprising 2299 participants met the inclusion criteria. In terms of efficacy, all intensity levels of ESWT were more effective than placebo, with ORs ranging from 2.29 (95% CI 1.39-3.76) for medium intensity ESWT (M-ESWT) to 5.50 (95% CI 1.00-30.29) for low intensity ESWT (L-ESWT). In terms of acceptability, there was no statistically significant difference between all intensity levels of ESWT and placebo, with ORs ranging from 0.83 (0.47-1.45) for M-ESWT to 1.42 (0.19-10.71) for L-ESWT. For pain relief, only M-ESWT and H-ESWT were superior to placebo (SMD -0.60, 95% CI -0.94 to -0.26; SMD -0.28, 95% CI -0.44 to -0.11), whereas there was no difference between them (p = .05). For function improved, there was no statistically significant difference between all intensity levels of ESWT and placebo (range of ORs 1.02-3.44). In contrast, there were no significant differences among the intensity levels in all outcomes. Of the 22 trials, 7 (32%) were assessed as high risk of bias, and the rest (68%) were assessed as unclear risk. The certainty of evidence was low to very low.</p><p><strong>Conclusion: </strong>Compared to the placebo, all intensity levels of ESWT were more favorable in terms of efficacy, but there was no difference in terms of acceptability. In addition, M-ESWT appeared to provide additional benefits in pain and function for patients with PHP compared to the other intensity levels. The results provide an evidence-based basis for considering ESWT as an alternative for patients with PHP for whom conservative treatment is not effective, and also highlight future research priorities to providing more decision-making for the clinical management of PHP.</p>","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1481-1493"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Academy News - December 2025 PM&R. 学院新闻- 2025年12月。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 DOI: 10.1002/pmrj.70089
{"title":"Academy News - December 2025 PM&R.","authors":"","doi":"10.1002/pmrj.70089","DOIUrl":"https://doi.org/10.1002/pmrj.70089","url":null,"abstract":"","PeriodicalId":20354,"journal":{"name":"PM&R","volume":"17 12","pages":"1521-1522"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145775425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An innovative prehabilitation approach for lung transplant candidates. 肺移植候选人的创新康复方法。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-05-23 DOI: 10.1002/pmrj.13410
Karen P Barr, George Tankosich, Bryan Willey

Background: Frailty is a risk factor for poor outcomes in lung transplantation. Identifying the causes of frailty and addressing reversible risk factors that contribute to poor outcomes in this population is complex.

Objective: To describe the results of frailty measures associated with poor outcomes and the prehabilitation plan prescribed for patients at their initial assessment for lung transplantation at our institution. We describe how a prehabilitation approach to improve function and mitigate risk factors can be incorporated into lung transplant selection committee recommendations.

Methods: Data were analyzed from 186 patients seen in an outpatient physical medicine and rehabilitation (PM&R) clinic as part of their initial assessment for lung transplantation and their lung selection committee recommendations.

Results: All 186 patients who initiated evaluation for lung transplant were evaluated by PM&R during their transplant initial evaluation period. Low objective and self-reported physical function were present in the majority of patients. All patients received a multimodal prehabilitation plan to address these reversible risk factors. Prehabilitation recommendations were integrated into their lung selection committee recommendations.

Conclusion: A comprehensive physiatric assessment for the purpose of identifying reversible risk factors for poor outcomes such as frailty and prescribing interventions to improve function is a feasible addition to the lung transplant evaluation process. This patient population has high prehabilitation needs.

背景:虚弱是肺移植预后不良的危险因素。在这一人群中,确定虚弱的原因和解决导致不良结果的可逆风险因素是复杂的。目的:描述与预后不良相关的虚弱指标的结果,以及在我院对肺移植患者进行初步评估时规定的康复计划。我们描述了如何将改善功能和减轻危险因素的康复方法纳入肺移植选择委员会的建议。方法:对186名门诊物理医学与康复(PM&R)患者的数据进行分析,作为他们对肺移植的初步评估和肺选择委员会建议的一部分。结果:186例开始肺移植评估的患者均在移植初始评估期进行了PM&R评估。大多数患者客观和自我报告的身体功能低下。所有患者都接受了多模式康复计划,以解决这些可逆的危险因素。康复建议被纳入他们的肺选择委员会的建议。结论:在肺移植评估过程中,进行全面的生理评估,以确定虚弱等不良结果的可逆危险因素,并开具改善功能的干预措施,是可行的补充。这类患者有很高的康复需求。
{"title":"An innovative prehabilitation approach for lung transplant candidates.","authors":"Karen P Barr, George Tankosich, Bryan Willey","doi":"10.1002/pmrj.13410","DOIUrl":"10.1002/pmrj.13410","url":null,"abstract":"<p><strong>Background: </strong>Frailty is a risk factor for poor outcomes in lung transplantation. Identifying the causes of frailty and addressing reversible risk factors that contribute to poor outcomes in this population is complex.</p><p><strong>Objective: </strong>To describe the results of frailty measures associated with poor outcomes and the prehabilitation plan prescribed for patients at their initial assessment for lung transplantation at our institution. We describe how a prehabilitation approach to improve function and mitigate risk factors can be incorporated into lung transplant selection committee recommendations.</p><p><strong>Methods: </strong>Data were analyzed from 186 patients seen in an outpatient physical medicine and rehabilitation (PM&R) clinic as part of their initial assessment for lung transplantation and their lung selection committee recommendations.</p><p><strong>Results: </strong>All 186 patients who initiated evaluation for lung transplant were evaluated by PM&R during their transplant initial evaluation period. Low objective and self-reported physical function were present in the majority of patients. All patients received a multimodal prehabilitation plan to address these reversible risk factors. Prehabilitation recommendations were integrated into their lung selection committee recommendations.</p><p><strong>Conclusion: </strong>A comprehensive physiatric assessment for the purpose of identifying reversible risk factors for poor outcomes such as frailty and prescribing interventions to improve function is a feasible addition to the lung transplant evaluation process. This patient population has high prehabilitation needs.</p>","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1505-1509"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury. 比较创伤性脑损伤新运动评估的敏感性和特异性。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-06-06 DOI: 10.1002/pmrj.13411
Paula K Johnson, Ariana M Hedges-Muncy, Erin D Bigler, Lorie Richards, Steven K Charles

Background: Portable technology that records movements with high accuracy provides potential for sensitive clinical movement tests for individuals who experienced a traumatic brain injury (TBI).

Objective: (1)To present impairments assessed using markerless motion capture (MMC) and (2) to compare the sensitivity and specificity of the MMC-mediated tests to each other and to common clinical tests.

Design: Screening study, using as criterion standard the ability to classify participant with TBI versus control participant.

Setting: Research laboratory.

Participants: The study included 30 individuals with TBI and 101 control participants. Entry criteria included most recent head injury <5 years old, no history of movement issues prior to injury, no movement-affecting medications, and sufficient cognitive ability to follow instructions.

Interventions: Not applicable.

Main outcome measures: Performance on MMC-mediated tests and existing clinical analogs. MMC-mediated tests included finger oscillation, simple reaction time, and visually guided movement tasks. For comparison, participants also completed the following clinical tests: Halstead-Reitan finger tapping, simple reaction time test, and Beery Visuomotor Integration test. Impairments were identified as test scores of participants with TBI that fell outside of the 95% interval of control participants' test scores. Random forest analysis was used to calculate the sensitivity and specificity of MMC and clinical tests according to their ability to correctly classify participants with TBI and control participants.

Results: MMC-mediated tests revealed impairments in more participants with TBI than clinical tests in all three TBI groups (mild, repeated, and moderate to severe). Similarly, MMC-mediated tests revealed a higher percentage of scores as impairments than clinical tests in all three groups with TBI. Furthermore, MMC-mediated tests proved more sensitive and more specific than clinical tests (70% versus 50% and 98% versus 93%, respectively).

Conclusion: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.

背景:便携式技术,记录运动的高精度提供了敏感的临床运动测试的潜力,个人谁经历了创伤性脑损伤(TBI)。目的:(1)介绍使用无标记运动捕捉(MMC)评估的损伤;(2)比较MMC介导的测试相互之间以及与常见临床测试的敏感性和特异性。设计:筛选研究,将TBI受试者与对照组受试者进行分类的能力作为标准。环境:研究实验室。参与者:该研究包括30名TBI患者和101名对照组。进入标准包括最近的头部损伤干预措施:不适用。主要结局指标:mmc介导试验和现有临床类似物的表现。mmc介导的测试包括手指振荡、简单反应时间和视觉引导的运动任务。为了比较,参与者还完成了以下临床测试:Halstead-Reitan手指敲击,简单反应时间测试和Beery视觉运动整合测试。损伤被确定为TBI参与者的测试分数落在对照组参与者测试分数的95%区间之外。采用随机森林分析,根据MMC和临床试验对TBI参与者和对照组参与者的正确分类能力,计算其敏感性和特异性。结果:mmc介导的测试显示,在所有三种TBI组(轻度、重复和中度至重度)中,更多的TBI参与者出现损伤。同样,在所有三组TBI患者中,mmc介导的测试显示得分为损伤的百分比高于临床测试。此外,mmc介导的测试证明比临床测试更敏感和更特异性(分别为70%对50%和98%对93%)。结论:与传统临床试验相比,mmc介导的试验具有敏感性和特异性,有可能填补TBI临床护理的空白。
{"title":"Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury.","authors":"Paula K Johnson, Ariana M Hedges-Muncy, Erin D Bigler, Lorie Richards, Steven K Charles","doi":"10.1002/pmrj.13411","DOIUrl":"10.1002/pmrj.13411","url":null,"abstract":"<p><strong>Background: </strong>Portable technology that records movements with high accuracy provides potential for sensitive clinical movement tests for individuals who experienced a traumatic brain injury (TBI).</p><p><strong>Objective: </strong>(1)To present impairments assessed using markerless motion capture (MMC) and (2) to compare the sensitivity and specificity of the MMC-mediated tests to each other and to common clinical tests.</p><p><strong>Design: </strong>Screening study, using as criterion standard the ability to classify participant with TBI versus control participant.</p><p><strong>Setting: </strong>Research laboratory.</p><p><strong>Participants: </strong>The study included 30 individuals with TBI and 101 control participants. Entry criteria included most recent head injury <5 years old, no history of movement issues prior to injury, no movement-affecting medications, and sufficient cognitive ability to follow instructions.</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome measures: </strong>Performance on MMC-mediated tests and existing clinical analogs. MMC-mediated tests included finger oscillation, simple reaction time, and visually guided movement tasks. For comparison, participants also completed the following clinical tests: Halstead-Reitan finger tapping, simple reaction time test, and Beery Visuomotor Integration test. Impairments were identified as test scores of participants with TBI that fell outside of the 95% interval of control participants' test scores. Random forest analysis was used to calculate the sensitivity and specificity of MMC and clinical tests according to their ability to correctly classify participants with TBI and control participants.</p><p><strong>Results: </strong>MMC-mediated tests revealed impairments in more participants with TBI than clinical tests in all three TBI groups (mild, repeated, and moderate to severe). Similarly, MMC-mediated tests revealed a higher percentage of scores as impairments than clinical tests in all three groups with TBI. Furthermore, MMC-mediated tests proved more sensitive and more specific than clinical tests (70% versus 50% and 98% versus 93%, respectively).</p><p><strong>Conclusion: </strong>MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.</p>","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1421-1431"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of lower-extremity exoskeleton robot-assisted dual-task training versus walking training on gait and postural control after stroke: A randomized controlled trial. 下肢外骨骼机器人辅助双任务训练与步行训练对卒中后步态和姿势控制的影响:一项随机对照试验。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-06-20 DOI: 10.1002/pmrj.13419
Tingyu Zhang, Jiejiao Zheng, Jiming Tao, Yueying Xu, Xinglai Zhang, Chen Chen, Dongdong Liao, Xingyuan Li

Background: Therapeutic tools are critical for poststroke rehabilitation. The potential benefits of dual-task training assisted by a lower-extremity exoskeleton robot to enhance gait and postural control have yet to be studied.

Objective: To determine the effects of lower-extremity exoskeleton robot-assisted dual-task training on gait and postural control after stroke.

Design: Single-blind, randomized controlled trial.

Setting: Outpatient clinic and ward, Department of Rehabilitation Medicine, Huadong Hospital affiliated with Fudan University.

Participants: Forty-four participants in the recovery and sequela phases of stroke with deficits in gait and postural control.

Interventions: Participants were randomly assigned to two groups: lower-extremity exoskeleton robot-assisted walking cognitive dual-task training (experimental group) or lower-extremity exoskeleton robot-assisted walking training (control group). Each participant received 40 minutes per intervention, 1 time per day, 6 times per week for 3 weeks.

Main outcome measures: The primary outcome was gait variability performance. The secondary outcomes included the Timed Up and Go, Berg Balance Scale, Montreal Cognitive Assessment, Fugl-Meyer assessment of lower extremity, and International Classification of Functioning, Disability and Health-activities and participation assessment scale.

Results: Individuals who participated in exoskeleton robot-assisted walking cognitive dual-task training improved more than those in the control group in partial gait variability performance analysis, Timed Up and Go test, Berg Balance Scale, and Fugl-Meyer assessment for the lower extremities (p < .05).

Conclusions: Compared to lower-extremity exoskeleton robot-assisted walking training, robot-assisted dual-task training improves gait and postural control, walking, balance, and lower extremity motor function in survivors of stroke.

背景:治疗工具对脑卒中后康复至关重要。由下肢外骨骼机器人辅助的双任务训练对增强步态和姿势控制的潜在益处尚未研究。目的:探讨下肢外骨骼机器人辅助双任务训练对脑卒中后步态和姿势控制的影响。设计:单盲、随机对照试验。单位:复旦大学附属华东医院康复内科门诊及病房。参与者:44名在步态和姿势控制方面有缺陷的中风恢复期和后遗症期的参与者。干预措施:参与者被随机分为两组:下肢外骨骼机器人辅助行走认知双任务训练组(实验组)或下肢外骨骼机器人辅助行走训练组(对照组)。每位参与者每次干预40分钟,每天1次,每周6次,持续3周。主要结局指标:主要结局指标为步态变异性表现。次要结果包括Timed Up and Go、Berg平衡量表、Montreal认知评估、Fugl-Meyer下肢评估和国际功能、残疾和健康分类-活动和参与评估量表。结果:参与外骨骼机器人辅助行走认知双任务训练的个体在部分步态变异性性能分析、Timed Up and Go测试、Berg平衡量表和下肢Fugl-Meyer评估方面比对照组改善更多(p)。与下肢外骨骼机器人辅助行走训练相比,机器人辅助双任务训练可以改善中风幸存者的步态和姿势控制、行走、平衡和下肢运动功能。
{"title":"Effects of lower-extremity exoskeleton robot-assisted dual-task training versus walking training on gait and postural control after stroke: A randomized controlled trial.","authors":"Tingyu Zhang, Jiejiao Zheng, Jiming Tao, Yueying Xu, Xinglai Zhang, Chen Chen, Dongdong Liao, Xingyuan Li","doi":"10.1002/pmrj.13419","DOIUrl":"10.1002/pmrj.13419","url":null,"abstract":"<p><strong>Background: </strong>Therapeutic tools are critical for poststroke rehabilitation. The potential benefits of dual-task training assisted by a lower-extremity exoskeleton robot to enhance gait and postural control have yet to be studied.</p><p><strong>Objective: </strong>To determine the effects of lower-extremity exoskeleton robot-assisted dual-task training on gait and postural control after stroke.</p><p><strong>Design: </strong>Single-blind, randomized controlled trial.</p><p><strong>Setting: </strong>Outpatient clinic and ward, Department of Rehabilitation Medicine, Huadong Hospital affiliated with Fudan University.</p><p><strong>Participants: </strong>Forty-four participants in the recovery and sequela phases of stroke with deficits in gait and postural control.</p><p><strong>Interventions: </strong>Participants were randomly assigned to two groups: lower-extremity exoskeleton robot-assisted walking cognitive dual-task training (experimental group) or lower-extremity exoskeleton robot-assisted walking training (control group). Each participant received 40 minutes per intervention, 1 time per day, 6 times per week for 3 weeks.</p><p><strong>Main outcome measures: </strong>The primary outcome was gait variability performance. The secondary outcomes included the Timed Up and Go, Berg Balance Scale, Montreal Cognitive Assessment, Fugl-Meyer assessment of lower extremity, and International Classification of Functioning, Disability and Health-activities and participation assessment scale.</p><p><strong>Results: </strong>Individuals who participated in exoskeleton robot-assisted walking cognitive dual-task training improved more than those in the control group in partial gait variability performance analysis, Timed Up and Go test, Berg Balance Scale, and Fugl-Meyer assessment for the lower extremities (p < .05).</p><p><strong>Conclusions: </strong>Compared to lower-extremity exoskeleton robot-assisted walking training, robot-assisted dual-task training improves gait and postural control, walking, balance, and lower extremity motor function in survivors of stroke.</p>","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1400-1410"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of balance training with visual occlusion on postural control in individuals with chronic ankle instability: A systematic review and meta-analysis of randomized controlled trials. 视力遮挡下平衡训练对慢性踝关节不稳定患者姿势控制的影响:随机对照试验的系统回顾和荟萃分析。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-06-17 DOI: 10.1002/pmrj.13413
Peng Chen, Lulu Yin, Yaru Wei, Yixue Gong, Lin Wang

Objective: Balance training with visual occlusion positively affects the improvement of proprioception and reduction of visual dependence in individuals with chronic ankle instability (CAI). However, the effect of visual occlusion balance training alone on postural control in individuals with CAI remains controversial. This review conducted a meta-analysis of existing randomized controlled trials (RCTs) to investigate the influence of balance training with visual occlusion on the postural control of individuals with CAI.

Literature survey: PubMed, Embase, The Cochrane Library, Web of Science, EBSCO, China National Knowledge Infrastructure (CNKI), and WanFang database were searched until July 20, 2024. RCTs were eligible if they compared the effects of balance training with visual occlusion with balance training on the postural control of individuals with CAI.

Methodology: The following information from the included articles was extracted: basic study information, interventions, and outcomes. The primary outcomes included Y-balance test (YBT) distance and center of pressure (COP) area, and the secondary outcomes were Cumberland ankle instability tool (CAIT) and Foot and Ankle Ability Measure (FAAM) scores.

Synthesis: Eight RCTs were included in this work. The results show that balance training with visual occlusion significantly improved YBT distance (standardized mean difference [SMD] = 0.40 [95% confidence interval [CI], 0.23-0.57], p < .001) and CAIT scores (mean difference [MD] = 3.03 [95% CI, 1.76-4.29], p < .001) in individuals with CAI compared with balance training alone. However, no significant difference was found between the two groups in terms of the COP area (SMD = 0.18 [95% CI, 0.51-0.86], p = .62) and FAAM scores (MD = 1.79 [95% CI, -0.03 to 3.62], p = .05).

Conclusions: Compared with balance training alone, balance training with visual occlusion may help improve the dynamic postural control ability of individuals with CAI. However, its effect on static postural control ability still needs further study.

目的:视觉遮挡下的平衡训练对慢性踝关节不稳定(CAI)患者本体感觉的改善和视觉依赖性的降低有积极的影响。然而,单独的视觉遮挡平衡训练对CAI患者姿势控制的影响仍然存在争议。本综述对现有的随机对照试验(RCTs)进行了荟萃分析,以研究视觉遮挡下的平衡训练对CAI患者姿势控制的影响。文献调查:检索PubMed、Embase、Cochrane Library、Web of Science、EBSCO、CNKI、万方数据库,检索截止至2024年7月20日。如果比较视觉遮挡下的平衡训练和平衡训练对CAI患者姿势控制的影响,则rct是合格的。方法:从纳入的文章中提取以下信息:基本研究信息、干预措施和结果。主要指标为y -平衡试验(YBT)距离和压力中心(COP)面积,次要指标为Cumberland踝关节不稳定工具(CAIT)和足踝关节能力测量(FAAM)评分。综合:本研究纳入8项随机对照试验。结果显示,视觉遮挡下的平衡训练显著提高了YBT距离(标准化平均差[SMD] = 0.40[95%可信区间[CI], 0.23-0.57], p)。结论:与单纯的平衡训练相比,视觉遮挡下的平衡训练有助于提高CAI患者的动态姿势控制能力。但其对静态姿势控制能力的影响还有待进一步研究。
{"title":"Effects of balance training with visual occlusion on postural control in individuals with chronic ankle instability: A systematic review and meta-analysis of randomized controlled trials.","authors":"Peng Chen, Lulu Yin, Yaru Wei, Yixue Gong, Lin Wang","doi":"10.1002/pmrj.13413","DOIUrl":"10.1002/pmrj.13413","url":null,"abstract":"<p><strong>Objective: </strong>Balance training with visual occlusion positively affects the improvement of proprioception and reduction of visual dependence in individuals with chronic ankle instability (CAI). However, the effect of visual occlusion balance training alone on postural control in individuals with CAI remains controversial. This review conducted a meta-analysis of existing randomized controlled trials (RCTs) to investigate the influence of balance training with visual occlusion on the postural control of individuals with CAI.</p><p><strong>Literature survey: </strong>PubMed, Embase, The Cochrane Library, Web of Science, EBSCO, China National Knowledge Infrastructure (CNKI), and WanFang database were searched until July 20, 2024. RCTs were eligible if they compared the effects of balance training with visual occlusion with balance training on the postural control of individuals with CAI.</p><p><strong>Methodology: </strong>The following information from the included articles was extracted: basic study information, interventions, and outcomes. The primary outcomes included Y-balance test (YBT) distance and center of pressure (COP) area, and the secondary outcomes were Cumberland ankle instability tool (CAIT) and Foot and Ankle Ability Measure (FAAM) scores.</p><p><strong>Synthesis: </strong>Eight RCTs were included in this work. The results show that balance training with visual occlusion significantly improved YBT distance (standardized mean difference [SMD] = 0.40 [95% confidence interval [CI], 0.23-0.57], p < .001) and CAIT scores (mean difference [MD] = 3.03 [95% CI, 1.76-4.29], p < .001) in individuals with CAI compared with balance training alone. However, no significant difference was found between the two groups in terms of the COP area (SMD = 0.18 [95% CI, 0.51-0.86], p = .62) and FAAM scores (MD = 1.79 [95% CI, -0.03 to 3.62], p = .05).</p><p><strong>Conclusions: </strong>Compared with balance training alone, balance training with visual occlusion may help improve the dynamic postural control ability of individuals with CAI. However, its effect on static postural control ability still needs further study.</p>","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1494-1504"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustain our subspecialty! Addressing the crisis within spinal cord injury medicine. 坚持我们的亚专业!解决脊髓损伤医学中的危机。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-05-28 DOI: 10.1002/pmrj.13421
Jelena N Svircev, Camilo Castillo
{"title":"Sustain our subspecialty! Addressing the crisis within spinal cord injury medicine.","authors":"Jelena N Svircev, Camilo Castillo","doi":"10.1002/pmrj.13421","DOIUrl":"10.1002/pmrj.13421","url":null,"abstract":"","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1515-1516"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between running gait biomechanics and femoral neck bone stress injuries in female runners. 跑步步态生物力学与女性跑步者股骨颈骨应力损伤的关系。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-06-17 DOI: 10.1002/pmrj.13418
Kristin E Whitney, Mayela Leal Chanchi, Pierre A d'Hemecourt, Andrea Stracciolini, Mininder Kocher, Corey Dawkins, Sarah Willwerth, Alexandra F DeJong Lempke

Background: Femoral neck stress fractures are prevalent injuries among young female runners, yet biomechanical and strength features have not been well-described in adolescents and young adults.

Objective: To compare running gait biomechanics and strength measures of female runners diagnosed with a femoral neck bone stress injury (BSI) to healthy female runner controls.

Design: Retrospective case-control study.

Setting: Outpatient sports medicine department.

Patients: There were 18 female runners with a history of femoral neck BSI (age: 20.3 ± 1.0 years, BMI: 19.8 ± 0.6 kg/m2) and 18 healthy female runners without femoral neck BSI (age: 18.3 ± 0.7 years, BMI: 21.5 ± 0.6 kg/m2).

Methods: Participants underwent instrumented running gait analyses with 2-dimensional videos, and standardized handheld dynamometry hip strength measures.

Main outcome measures: Primary outcomes included spatiotemporal, kinematic, and kinetic running gait biomechanics, and tri-planar hip muscle strength. Non-parametric Mann-Whitney U tests were used to compare participant demographics. Linear regressions were used to compare strength and continuous gait outcomes, and logistic regressions were used to compare categorical gait outcomes between groups, covarying for age and body mass index (α = .05).

Results: A higher proportion of those with a history of femoral neck BSI demonstrated limb midline cross-over (Adjusted Probability [Adj.]: 65.0% vs. 38.5 %; p = .04), contralateral pelvic drop (Adj.: 99.0% vs. 52.9%; p = .02), medial knee displacement (Adj.: 67.0% vs. 37.9%; p = .03), and pronation at midstance (Adj.: 86.5% vs. 41.2%; p = .02) compared to those without a history of BSI. Those with a history of femoral neck BSI had lower hip abduction strength on dynamometry testing (1.64 ± 0.30 Nm/kg vs. 1.99 ± 0.66 Nm/kg; p = .01).

Conclusions: Female runners with a history of femoral neck BSI demonstrated characteristic coronal plane gait and hip abductor strength deficits, suggesting an association between impaired lower limb proximal and distal biomechanics during femoral neck BSI recovery.

背景:股骨颈应力性骨折是年轻女性跑步者中常见的损伤,但青少年和年轻人的生物力学和力量特征尚未得到很好的描述。目的:比较诊断为股骨颈骨应力性损伤(BSI)的女性跑步者与健康女性跑步者的跑步步态生物力学和力量测量。设计:回顾性病例对照研究。单位:运动医学科门诊。患者:有股骨颈BSI病史的女性跑步者18例(年龄:20.3±1.0岁,BMI: 19.8±0.6 kg/m2),无股骨颈BSI的健康女性跑步者18例(年龄:18.3±0.7岁,BMI: 21.5±0.6 kg/m2)。方法:参与者通过二维视频进行跑步步态分析,并进行标准化手持式髋部力量测量。主要结局指标:主要结局包括时空、运动学和动力学跑步步态生物力学和髋关节三平面肌力。非参数Mann-Whitney U检验用于比较参与者的人口统计学特征。使用线性回归比较力量和连续步态结果,使用逻辑回归比较组间分类步态结果,协变年龄和体重指数(α = 0.05)。结果:股骨颈BSI病史者出现肢体中线交叉的比例较高(调整概率[j]: 65.0% vs. 38.5%;p = .04),对侧盆腔下垂(Adj.: 99.0% vs. 52.9%;p = .02),膝关节内侧移位(差异:67.0% vs. 37.9%;p = .03),中位旋前(比值:86.5% vs. 41.2%;p = .02)。有股骨颈BSI病史的患者髋外展强度较低(1.64±0.30 Nm/kg vs 1.99±0.66 Nm/kg);p = 0.01)。结论:有股骨颈BSI病史的女性跑步者表现出特征性的冠状面步态和髋关节外展肌力量缺陷,这表明在股骨颈BSI恢复过程中下肢近端和远端生物力学损伤之间存在关联。
{"title":"Association between running gait biomechanics and femoral neck bone stress injuries in female runners.","authors":"Kristin E Whitney, Mayela Leal Chanchi, Pierre A d'Hemecourt, Andrea Stracciolini, Mininder Kocher, Corey Dawkins, Sarah Willwerth, Alexandra F DeJong Lempke","doi":"10.1002/pmrj.13418","DOIUrl":"10.1002/pmrj.13418","url":null,"abstract":"<p><strong>Background: </strong>Femoral neck stress fractures are prevalent injuries among young female runners, yet biomechanical and strength features have not been well-described in adolescents and young adults.</p><p><strong>Objective: </strong>To compare running gait biomechanics and strength measures of female runners diagnosed with a femoral neck bone stress injury (BSI) to healthy female runner controls.</p><p><strong>Design: </strong>Retrospective case-control study.</p><p><strong>Setting: </strong>Outpatient sports medicine department.</p><p><strong>Patients: </strong>There were 18 female runners with a history of femoral neck BSI (age: 20.3 ± 1.0 years, BMI: 19.8 ± 0.6 kg/m<sup>2</sup>) and 18 healthy female runners without femoral neck BSI (age: 18.3 ± 0.7 years, BMI: 21.5 ± 0.6 kg/m<sup>2</sup>).</p><p><strong>Methods: </strong>Participants underwent instrumented running gait analyses with 2-dimensional videos, and standardized handheld dynamometry hip strength measures.</p><p><strong>Main outcome measures: </strong>Primary outcomes included spatiotemporal, kinematic, and kinetic running gait biomechanics, and tri-planar hip muscle strength. Non-parametric Mann-Whitney U tests were used to compare participant demographics. Linear regressions were used to compare strength and continuous gait outcomes, and logistic regressions were used to compare categorical gait outcomes between groups, covarying for age and body mass index (α = .05).</p><p><strong>Results: </strong>A higher proportion of those with a history of femoral neck BSI demonstrated limb midline cross-over (Adjusted Probability [Adj.]: 65.0% vs. 38.5 %; p = .04), contralateral pelvic drop (Adj.: 99.0% vs. 52.9%; p = .02), medial knee displacement (Adj.: 67.0% vs. 37.9%; p = .03), and pronation at midstance (Adj.: 86.5% vs. 41.2%; p = .02) compared to those without a history of BSI. Those with a history of femoral neck BSI had lower hip abduction strength on dynamometry testing (1.64 ± 0.30 Nm/kg vs. 1.99 ± 0.66 Nm/kg; p = .01).</p><p><strong>Conclusions: </strong>Female runners with a history of femoral neck BSI demonstrated characteristic coronal plane gait and hip abductor strength deficits, suggesting an association between impaired lower limb proximal and distal biomechanics during femoral neck BSI recovery.</p>","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1432-1442"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary on "Racial disparities in patients with amputation in an acute care setting in the immediate postoperative period". 评论“截肢患者在术后急性护理环境中的种族差异”。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-10-22 DOI: 10.1002/pmrj.70044
Majid Khalilizad, Mostafa Javanian, Mohammad Barary, Romina Hamzehpour, Soheil Ebrahimpour
{"title":"Commentary on \"Racial disparities in patients with amputation in an acute care setting in the immediate postoperative period\".","authors":"Majid Khalilizad, Mostafa Javanian, Mohammad Barary, Romina Hamzehpour, Soheil Ebrahimpour","doi":"10.1002/pmrj.70044","DOIUrl":"10.1002/pmrj.70044","url":null,"abstract":"","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1517-1518"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145346808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding medical students' knowledge and attitudes about cerebral palsy. 了解医学生对脑瘫的认识和态度。
IF 2.8 4区 医学 Q1 REHABILITATION Pub Date : 2025-12-01 Epub Date: 2025-06-19 DOI: 10.1002/pmrj.13420
Brianna Callahan, Andrea Janis, Swetha Reddi, Andrew S Nowak, Ronald Thomas, Karin Przyklenk, Christina Santia, Charles Pelshaw

Background: Children with cerebral palsy and other disabilities face barriers in obtaining equitable medical care. Although many factors contribute to these disparities, physicians' lack of knowledge and comfort when caring for patients with cerebral palsy have been reported to play a role. We propose that this gap in understanding may reflect a deficit in disability education during medical school.

Objective: To (1) obtain insight into medical students' knowledge regarding cerebral palsy at two medical schools in the United States; and (2) determine whether viewing a brief educational video increases short-term knowledge regarding cerebral palsy.

Methods: All medical students attending Wayne State University School of Medicine and Central Michigan University College of Medicine in November-December 2023 were invited to participate in the study. Respondents completed a three-step survey, in which they answered nine multiple-choice knowledge-based questions about cerebral palsy, viewed a 10-minute educational video, and responded to the same nine knowledge-based questions after viewing the video.

Results: A total of 221 surveys were received (response rate: 14%). For the submitted surveys in which paired data were available, the percentage of correct responses at baseline (prevideo), averaged for the nine knowledge-based questions, was 45 ± 15% and increased to 67 ± 11% after viewing the educational video (p < .01).

Conclusions: Our results reveal that medical students' knowledge of cerebral palsy is limited and that a brief, focused educational session may have a short-term beneficial effect in mitigating this gap in knowledge.

背景:脑瘫和其他残疾儿童在获得公平医疗保健方面面临障碍。尽管许多因素导致了这些差异,但据报道,医生在照顾脑瘫患者时缺乏知识和舒适度是其中一个原因。我们认为,这种理解上的差距可能反映了医学院残疾教育的不足。目的:(1)了解美国两所医学院医学生对脑瘫的认知情况;(2)判断观看简短的教育视频是否增加了关于脑瘫的短期知识。方法:邀请2023年11 - 12月就读于韦恩州立大学医学院和中密歇根大学医学院的所有医学生参与研究。受访者完成了一项三步调查,其中他们回答了九道关于脑瘫的选择题,观看了一段10分钟的教育视频,并在观看视频后回答了同样的九道知识问题。结果:共收到问卷221份,回复率为14%。在提交的调查中,有配对数据,9个知识基础问题的平均正确率在基线(视频前)为45±15%,在观看教育视频后增加到67±11% (p)结论:我们的研究结果表明,医学生对脑瘫的认识是有限的,一个简短的、有重点的教育课程可能会在短期内缓解这种知识差距。
{"title":"Understanding medical students' knowledge and attitudes about cerebral palsy.","authors":"Brianna Callahan, Andrea Janis, Swetha Reddi, Andrew S Nowak, Ronald Thomas, Karin Przyklenk, Christina Santia, Charles Pelshaw","doi":"10.1002/pmrj.13420","DOIUrl":"10.1002/pmrj.13420","url":null,"abstract":"<p><strong>Background: </strong>Children with cerebral palsy and other disabilities face barriers in obtaining equitable medical care. Although many factors contribute to these disparities, physicians' lack of knowledge and comfort when caring for patients with cerebral palsy have been reported to play a role. We propose that this gap in understanding may reflect a deficit in disability education during medical school.</p><p><strong>Objective: </strong>To (1) obtain insight into medical students' knowledge regarding cerebral palsy at two medical schools in the United States; and (2) determine whether viewing a brief educational video increases short-term knowledge regarding cerebral palsy.</p><p><strong>Methods: </strong>All medical students attending Wayne State University School of Medicine and Central Michigan University College of Medicine in November-December 2023 were invited to participate in the study. Respondents completed a three-step survey, in which they answered nine multiple-choice knowledge-based questions about cerebral palsy, viewed a 10-minute educational video, and responded to the same nine knowledge-based questions after viewing the video.</p><p><strong>Results: </strong>A total of 221 surveys were received (response rate: 14%). For the submitted surveys in which paired data were available, the percentage of correct responses at baseline (prevideo), averaged for the nine knowledge-based questions, was 45 ± 15% and increased to 67 ± 11% after viewing the educational video (p < .01).</p><p><strong>Conclusions: </strong>Our results reveal that medical students' knowledge of cerebral palsy is limited and that a brief, focused educational session may have a short-term beneficial effect in mitigating this gap in knowledge.</p>","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":"1473-1480"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
PM&R
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1