Pub Date : 2023-03-16DOI: 10.55858/ijimh0201(04)2023-08
Aynur Jabiyeva Aynur Jabiyeva
In order to increase the accuracy of clustering biomedical data, fuzzy co-clustering extends co-clustering by applying membership functions to both the objects and the characteristics. In this research, we provide a novel information bottleneck-based fuzzy co-clustering algorithm called ibFCC. The distance between a feature data point and the feature cluster centroid is calculated using the information bottleneck theory by the objective function called the ibFCC. Using five biomedical datasets, numerous experiments were done, and the ibFCC was compared to well-known fuzzy (co-)clustering algorithms as FCM, FCCM, RFCC, and FCCI. According to experimental data, ibFCC could produce high-quality clusters and was more accurate than any of these approaches
{"title":"A FUZZY CO-CLUSTERİNG ALGORİTHM FOR BİOMEDİCAL DATA","authors":"Aynur Jabiyeva Aynur Jabiyeva","doi":"10.55858/ijimh0201(04)2023-08","DOIUrl":"https://doi.org/10.55858/ijimh0201(04)2023-08","url":null,"abstract":"In order to increase the accuracy of clustering biomedical data, fuzzy co-clustering extends co-clustering by applying membership functions to both the objects and the characteristics. In this research, we provide a novel information bottleneck-based fuzzy co-clustering algorithm called ibFCC. The distance between a feature data point and the feature cluster centroid is calculated using the information bottleneck theory by the objective function called the ibFCC. Using five biomedical datasets, numerous experiments were done, and the ibFCC was compared to well-known fuzzy (co-)clustering algorithms as FCM, FCCM, RFCC, and FCCI. According to experimental data, ibFCC could produce high-quality clusters and was more accurate than any of these approaches","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134110995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-16DOI: 10.55858/ijimh0201(04)2023-18
Aynur Aliyeva Aynur Aliyeva, Ziya Karimov Ziya Karimov
Objective Thyroglossal duct cysts are the most common congenital neck mass in the midline of the neck. Cystic formations develop due to the partial or complete lack of obliteration of the thyroglossal duct. It may lead to transformation to malignancy, although rarely. Our study aims to discuss the outcomes, examination findings, clinical features, and treatment methods of 51 patients operated on for thyroglossal duct cysts to contribute to the literature. Methods The 51 cases that underwent surgery (Sistrunk, Cystectomy, Thyroidectomy) with a preliminary diagnosis of thyroglossal duct cyst in ENT and HNS clinics were evaluated retrospectively. The patient's sociodemographic data, main complaints, examination findings, diagnostic methods, surgical techniques, recurrence and complication rates after treatment, and pathology results were analyzed in this study. Results Of the 51 patients, 35 (69%) were adults, and 16 (31%) were children. The most common reason 40 (78%) for admission was swelling in the midline of the neck, less commonly 8 (16%) swelling under the chin, 4 (8%) of patients with an average follow-up of 28 months (max 32; min 8; SD 3 months) were performed revision operations. Surgical treatment has consisted of the Sistrunk procedure (n = 47; 92%), cystectomy (n = 4; 8%), or thyroidectomy (n = 1; 2%). Papillary thyroid carcinoma was diagnosed in 2 (4%) patients, and medullary thyroid carcinoma was in 1 (2%) in our cases. They were no significant differences in gender and age, sociodemographics data. Conclusion Thyroglossal duct cysts should be considered in the differential diagnosis of patients presenting with swelling in the midline of the neck. Sistrunk operation, a safe surgical procedure with the least recurrence rate and a low risk of complications, is recommended as surgical treatment. Keywords: Thyroglossal duct cyst, Midline neck mass, Sistrunk operation
{"title":"THYROGLOSSAL DUCT CYSTS SURGERY OUTCOMES","authors":"Aynur Aliyeva Aynur Aliyeva, Ziya Karimov Ziya Karimov","doi":"10.55858/ijimh0201(04)2023-18","DOIUrl":"https://doi.org/10.55858/ijimh0201(04)2023-18","url":null,"abstract":"Objective\u0000Thyroglossal duct cysts are the most common congenital neck mass in the midline of the neck. Cystic formations develop due to the partial or complete lack of obliteration of the thyroglossal duct. It may lead to transformation to malignancy, although rarely. Our study aims to discuss the outcomes, examination findings, clinical features, and treatment methods of 51 patients operated on for thyroglossal duct cysts to contribute to the literature.\u0000\u0000Methods\u0000The 51 cases that underwent surgery (Sistrunk, Cystectomy, Thyroidectomy) with a preliminary diagnosis of thyroglossal duct cyst in ENT and HNS clinics were evaluated retrospectively. The patient's sociodemographic data, main complaints, examination findings, diagnostic methods, surgical techniques, recurrence and complication rates after treatment, and pathology results were analyzed in this study.\u0000\u0000Results\u0000Of the 51 patients, 35 (69%) were adults, and 16 (31%) were children. The most common reason 40 (78%) for admission was swelling in the midline of the neck, less commonly 8 (16%) swelling under the chin, 4 (8%) of patients with an average follow-up of 28 months (max 32; min 8; SD 3 months) were performed revision operations. Surgical treatment has consisted of the Sistrunk procedure (n = 47; 92%), cystectomy (n = 4; 8%), or thyroidectomy (n = 1; 2%). Papillary thyroid carcinoma was diagnosed in 2 (4%) patients, and medullary thyroid carcinoma was in 1 (2%) in our cases. They were no significant differences in gender and age, sociodemographics data.\u0000\u0000Conclusion\u0000Thyroglossal duct cysts should be considered in the differential diagnosis of patients presenting with swelling in the midline of the neck. Sistrunk operation, a safe surgical procedure with the least recurrence rate and a low risk of complications, is recommended as surgical treatment.\u0000Keywords: Thyroglossal duct cyst, Midline neck mass, Sistrunk operation","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134144340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Any rational anesthesia strategy should focus on intraoperative and postoperative pain control. Adverse effects of opioids on the course of the early postoperative period are known. The aim of our study is to determine the correlations of acute postoperative pain with different types of anesthesia. Methods 203 patients who underwent abdominal plastic and bariatric surgery were under our observation; 113 (55.67%) of them are women and 90 (44.33%) are men; Among them, 154 patients underwent abdominoplasty, and 49 underwent bariatric surgery. Standard anesthesia with opioids was administered to 49 (24.14%) patients - group I, multimodal + partial use of opioids - group II: 76 (37.44%), multimodal anesthesia - 78 (38.42%) - group III. Results During anesthesia with opioids, compared to the second and third groups, the pain in the operative area, as well as in the head, throat, waist and ears is significantly higher. During multimodal anesthesia, pain is reliably less in all cases, and pain in the throat was not noted. Correlation analysis showed that opioid anesthesia was significantly correlated with postoperative pain,: Pain in the operated area - r=0.504**, p<0.001; Head pain - r=0.395**, p<0.001; Throat pain - r=0.301**, p<0.001Waist painr=0.320**, <0.001, Muscles pain - r=0.422**, p<0.001 whereas multimodal anesthesia was significantly negatively correlated with all types of postoperative pain. In the second phase, in the opioid anesthesia group, compared to the second group, there is significantly more pain in the lower back and muscles, and in the third group, there was no pain at all. The frequency of patients who did not require medical treatment during the intrahospital stage is not significantly different from each other, and the pain requiring non-opioid treatment is significantly less after multimodal anesthesia - Group I - 28(57.14%), Group II - 25(32.89%), Group III - 2(2.56)(p<0.0001). Pain requires opioid medication - Group I - 20(40.82)Group II – 19(25.00%), (p<0.0001). No patient in this group required opioid treatment. In the ambulatory stage, no patient in the multimodal anesthesia group needed medical treatment, and significantly fewer patients in group II needed non-opioid treatment. Conclusion Multimodal anesthesia reduces perioperative pain and the need for perioperative opioid use. Keywords: Postoperative pain, Multimodal anesthesia, perioperative opioid use.
{"title":"POSTOPERATIVE PAIN AND MULTIMODAL ANESTHESIA IN ABDOMINAL PLASTIC AND BARIATRIC SURGERY","authors":"Ketevan Arabidze, Irakli Gogokhia Ketevan Arabidze, Irakli Gogokhia, Nodar Lebanidze, Iamze Taboridze Nodar Lebanidze, Iamze Taboridze","doi":"10.55858/ijimh0201(04)2023-23","DOIUrl":"https://doi.org/10.55858/ijimh0201(04)2023-23","url":null,"abstract":"Any rational anesthesia strategy should focus on intraoperative and postoperative pain control. Adverse effects of opioids on the course of the early postoperative period are known. \u0000The aim of our study is to determine the correlations of acute postoperative pain with different types of anesthesia.\u0000\u0000Methods\u0000203 patients who underwent abdominal plastic and bariatric surgery were under our observation; 113 (55.67%) of them are women and 90 (44.33%) are men; Among them, 154 patients underwent abdominoplasty, and 49 underwent bariatric surgery.\u0000Standard anesthesia with opioids was administered to 49 (24.14%) patients - group I, multimodal + partial use of opioids - group II: 76 (37.44%), multimodal anesthesia - 78 (38.42%) - group III.\u0000\u0000Results\u0000During anesthesia with opioids, compared to the second and third groups, the pain in the operative area, as well as in the head, throat, waist and ears is significantly higher.\u0000During multimodal anesthesia, pain is reliably less in all cases, and pain in the throat was not noted. Correlation analysis showed that opioid anesthesia was significantly correlated with postoperative pain,: Pain in the operated area - r=0.504**, p<0.001; Head pain - r=0.395**, p<0.001; Throat pain - r=0.301**, p<0.001Waist painr=0.320**, <0.001, Muscles pain - r=0.422**, p<0.001\u0000whereas multimodal anesthesia was significantly negatively correlated with all types of postoperative pain.\u0000In the second phase, in the opioid anesthesia group, compared to the second group, there is significantly more pain in the lower back and muscles, and in the third group, there was no pain at all.\u0000The frequency of patients who did not require medical treatment during the intrahospital stage is not significantly different from each other, and the pain requiring non-opioid treatment is significantly less after multimodal anesthesia - Group I - 28(57.14%), Group II - 25(32.89%), Group III - 2(2.56)(p<0.0001). Pain requires opioid medication - Group I - 20(40.82)Group II – 19(25.00%), (p<0.0001). No patient in this group required opioid treatment.\u0000In the ambulatory stage, no patient in the multimodal anesthesia group needed medical treatment, and significantly fewer patients in group II needed non-opioid treatment.\u0000\u0000Conclusion\u0000Multimodal anesthesia reduces perioperative pain and the need for perioperative opioid use. \u0000Keywords: Postoperative pain, Multimodal anesthesia, perioperative opioid use.","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122056734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Early diagnosis of various diseases significantly improves survival. However, more than half of these cases are diagnosed late due to the high demand for colonoscopy - the "gold standard" of screening. Colonoscopy is limited by the outdated design of conventional endoscopes due to the high complexity and cost of use. Magnetic endoscopes are a promising alternative and overcome the cost disadvantages, but their translational phase is difficult to achieve because magnetic manipulations are complex and unintuitive. In this work, we use machine vision to develop an intelligent and autonomous endoscope control that allows non-expert users to efficiently perform in vivo magnetic colonoscopy. We combine the use of robotics, computer vision, and advanced control to offer an intuitive and efficient endoscopic system. Furthermore, we define the characteristics required to achieve autonomy in robotic endoscopy. The paradigm described here can be applied to a variety of applications requiring navigation in an unstructured environment, such as catheters, pancreatic endoscopy, bronchoscopy, and gastroscopy. This work brings alternative endoscopic technologies closer to the translational stage, increasing the availability of early disease treatment. Keywords: endoscope models, portable, capsule, mobile systems, mobile devices, picture completeness, modern technology
{"title":"INTELLIGENT BIOMEDICAL MEASUREMENT SYSTEM","authors":"Lala Bekirova Lala Bekirova, Ravan Gambarov Ravan Gambarov","doi":"10.55858/ijimh0201(04)2023-49","DOIUrl":"https://doi.org/10.55858/ijimh0201(04)2023-49","url":null,"abstract":"Early diagnosis of various diseases significantly improves survival. However, more than half of these cases are diagnosed late due to the high demand for colonoscopy - the \"gold standard\" of screening. Colonoscopy is limited by the outdated design of conventional endoscopes due to the high complexity and cost of use. Magnetic endoscopes are a promising alternative and overcome the cost disadvantages, but their translational phase is difficult to achieve because magnetic manipulations are complex and unintuitive. In this work, we use machine vision to develop an intelligent and autonomous endoscope control that allows non-expert users to efficiently perform in vivo magnetic colonoscopy. We combine the use of robotics, computer vision, and advanced control to offer an intuitive and efficient endoscopic system. Furthermore, we define the characteristics required to achieve autonomy in robotic endoscopy. The paradigm described here can be applied to a variety of applications requiring navigation in an unstructured environment, such as catheters, pancreatic endoscopy, bronchoscopy, and gastroscopy. This work brings alternative endoscopic technologies closer to the translational stage, increasing the availability of early disease treatment.\u0000Keywords: endoscope models, portable, capsule, mobile systems, mobile devices, picture completeness, modern technology","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131588073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The aim of this study was identification of the allergic sensitivities of Syrian refugee children residing in Western Turkey and diagnosed with various allergic diseases. Materials and methods: Syrian refugee children younger than 18 constituted the target population of this study. A group of patients were assigned to the control group. The levels of total immunoglobulin E, A, G, M, eosinophil counts and percentages, and the results of inhalant and food allergy tests of patients and controls were all recorded. Results: The entire study cohort consisted of 34 patients (23 boys, 11 girls) in the study group and 30 patients (20 boys, 10 girls) in the control group. There were statistically significant relationships between patients and controls about eosinophil counts and percentages (p= 0.005, p < 0.0001, respectively). Conclusion: Our study is the first report investigating the allergic sensitivities of Syrian children to the best of our knowledge. We believe that our findings will enlighten the approach of the clinicians taking care of Syrian children in different countries hosting Syrian refugees. Keywords: inhalant allergen sensitivity, food allergen sensitivity, Syrian refugee, allergic disease
背景:本研究的目的是鉴定居住在土耳其西部的叙利亚难民儿童的过敏敏感性，并诊断为各种过敏性疾病。材料与方法:18岁以下的叙利亚难民儿童构成本研究的目标人群。一组患者被分配到对照组。记录患者和对照组的总免疫球蛋白E、A、G、M水平、嗜酸性粒细胞计数和百分比，以及吸入剂和食物过敏试验结果。结果:整个研究队列包括研究组34例患者(男孩23例，女孩11例)和对照组30例患者(男孩20例，女孩10例)。患者与对照组的嗜酸性粒细胞计数和百分比有统计学意义(p= 0.005, p < 0.0001)。结论:据我们所知，我们的研究是第一份调查叙利亚儿童过敏敏感性的报告。我们相信，我们的研究结果将启发临床医生在收容叙利亚难民的不同国家照顾叙利亚儿童的方法。关键词:吸入性过敏原敏感性;食物过敏原敏感性;叙利亚难民
{"title":"INVESTIGATION OF ALLERGEN SENSITIVITY OF SYRIAN REFUGEE CHILDREN WITH ALLERGIC DISEASES","authors":"Emine Ece Ozdoğru Emine Ece Ozdoğru, Melis Gonulal Melis Gonulal","doi":"10.55858/ijimh01022022-42","DOIUrl":"https://doi.org/10.55858/ijimh01022022-42","url":null,"abstract":"Background: The aim of this study was identification of the allergic sensitivities of Syrian refugee children residing in Western Turkey and diagnosed with various allergic diseases. \u0000Materials and methods: Syrian refugee children younger than 18 constituted the target population of this study. A group of patients were assigned to the control group. The levels of total immunoglobulin E, A, G, M, eosinophil counts and percentages, and the results of inhalant and food allergy tests of patients and controls were all recorded.\u0000Results: The entire study cohort consisted of 34 patients (23 boys, 11 girls) in the study group and 30 patients (20 boys, 10 girls) in the control group. There were statistically significant relationships between patients and controls about eosinophil counts and percentages (p= 0.005, p < 0.0001, respectively). \u0000Conclusion: Our study is the first report investigating the allergic sensitivities of Syrian children to the best of our knowledge. We believe that our findings will enlighten the approach of the clinicians taking care of Syrian children in different countries hosting Syrian refugees.\u0000Keywords: inhalant allergen sensitivity, food allergen sensitivity, Syrian refugee, allergic disease","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115418669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-11DOI: 10.55858/ijimh01022022-28
Sain Safarova Sain Safarova
Violation of hormonal homeostasis in polycystic ovary syndrome (PCOS) causes a number of changes in the body of a woman in the postmenopausal period. One of the clinical features of the climacteric syndrome in PCOS is the presence of rare and weak hot flashes, a decrease in the menopausal peak of gonadotropins, and a distinct appearance of local urogenital symptoms. With age, in women with PCOS, a history of insulin resistance and dyslipidaemia predisposes them to early onset of cardiovascular disease and type 2 diabetes. Pathogenetic treatment of women with a history of PCOS in the postmenopausal period should be carried out in order to prevent atherosclerotic and metabolic complications. Keywords: postmenopause, polycystic ovary syndrome, insulin resistance
{"title":"AGE-RELATED CHANGES OF HORMONAL HOMEOSTASIS IN POLYCYSTOSIS \u0000OF OVARIANS","authors":"Sain Safarova Sain Safarova","doi":"10.55858/ijimh01022022-28","DOIUrl":"https://doi.org/10.55858/ijimh01022022-28","url":null,"abstract":"Violation of hormonal homeostasis in polycystic ovary syndrome (PCOS) causes a number of changes in the body of a woman in the postmenopausal period. One of the clinical features of the climacteric syndrome in PCOS is the presence of rare and weak hot flashes, a decrease in the menopausal peak of gonadotropins, and a distinct appearance of local urogenital symptoms. With age, in women with PCOS, a history of insulin resistance and dyslipidaemia predisposes them to early onset of cardiovascular disease and type 2 diabetes. Pathogenetic treatment of women with a history of PCOS in the postmenopausal period should be carried out in order to prevent atherosclerotic and metabolic complications.\u0000Keywords: postmenopause, polycystic ovary syndrome, insulin resistance","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126107536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-11DOI: 10.55858/ijimh01022022-38
Ulkar Asadova Ulkar Asadova
Goal: Investigate the role of cortexin in stopping and achieving remission of seizures in epilepsy. Material and methods: 47 patients with various forms of epilepsy were examined at the reception of a neurologist of the polyclinic department of the United City Hospital No. 7 during 2020-2021. To assess the psycho-emotional status, the Ziqmond scale was used. As a means of increasing stress resistance, cortexin was used. Statistical calculations of qualitative parameters were carried out using the Fisher criterion. The results are presented at the level of reliable significance p <0.05. Results and discussion: Psycho-emotional status, determined by the Ziqmond scale before treatment with cortexin, was rated low in all patients (6.91±0.13; m = 4, M = 11), and in female patients statistically significantly lower (8.05±0.32; m = 6, M = 13) than in male (8.83±0.21; m = 5, M = 12), (p = 0.046). During the study period (1 year), in 36 patients (31 cases from the group taking cortexin and 5 cases from the placebo group), seizures did not recur. The study proved a fairly high (83.78%) effectiveness of cortexin in improving the mental and emotional states of patients with epilepsy didn't repeat themselves. Conclusions: The inclusion of cortexin in the interictal period in the treatment regimen allows you to achieve a thymoleptic effect and prolong the remission of epileptic seizures. Keywords: polypeptide therapy, psycho-emotional status, cortexin, neuropeptides, epilepsy.
目的:探讨皮质素在癫痫发作停止和缓解中的作用。材料和方法:在2020-2021年期间，在联合城市医院第七综合门诊的神经科医生的接待下，对47例不同形式的癫痫患者进行了检查。采用Ziqmond量表评估心理情绪状态。作为提高抗逆性的手段，采用了皮质蛋白。定性参数的统计计算采用Fisher准则进行。结果在可靠显著性水平p <0.05。结果与讨论:所有患者使用皮质素治疗前的Ziqmond量表的心理情绪状态评分均为低(6.91±0.13;m = 4, m = 11)，女性患者差异有统计学意义(8.05±0.32;m = 6, m = 13)高于男性(8.83±0.21;m = 5, m = 12)， p = 0.046)。在研究期间(1年)，36例患者(服用皮质素组31例，安慰剂组5例)无癫痫发作复发。本研究证明，皮质素在改善癫痫患者的精神和情绪状态方面具有相当高的有效性(83.78%)。结论:在治疗方案的间歇期加入皮质素可以达到健胸效果并延长癫痫发作的缓解期。关键词:多肽治疗，心理情绪状态，皮质蛋白，神经肽，癫痫。
{"title":"EPTIDE THERAPY FOR EPILEPSY","authors":"Ulkar Asadova Ulkar Asadova","doi":"10.55858/ijimh01022022-38","DOIUrl":"https://doi.org/10.55858/ijimh01022022-38","url":null,"abstract":"Goal: Investigate the role of cortexin in stopping and achieving remission of seizures in epilepsy.\u0000Material and methods: 47 patients with various forms of epilepsy were examined at the reception of a neurologist of the polyclinic department of the United City Hospital No. 7 during 2020-2021. To assess the psycho-emotional status, the Ziqmond scale was used. As a means of increasing stress resistance, cortexin was used. Statistical calculations of qualitative parameters were carried out using the Fisher criterion. The results are presented at the level of reliable significance p <0.05.\u0000Results and discussion: Psycho-emotional status, determined by the Ziqmond scale before treatment with cortexin, was rated low in all patients (6.91±0.13; m = 4, M = 11), and in female patients statistically significantly lower (8.05±0.32; m = 6, M = 13) than in male (8.83±0.21; m = 5, M = 12), (p = 0.046). During the study period (1 year), in 36 patients (31 cases from the group taking cortexin and 5 cases from the placebo group), seizures did not recur. The study proved a fairly high (83.78%) effectiveness of cortexin in improving the mental and emotional states of patients with epilepsy didn't repeat themselves.\u0000Conclusions: The inclusion of cortexin in the interictal period in the treatment regimen allows you to achieve a thymoleptic effect and prolong the remission of epileptic seizures.\u0000Keywords: polypeptide therapy, psycho-emotional status, cortexin, neuropeptides, epilepsy.","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128295516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-11DOI: 10.55858/ijimh01022022-31
Aynur Jabiyeva Aynur Jabiyeva
Medical image fusion is the development of registry and fusion of different pots of one or more imaging modalities in order to improve image value and reduce uncertainty and concern, to improve the applicability of the medical image for clinical opinion or the evaluation of medical care. difficulties. Multimodal medical image fusion algorithms and devices have achieved a remarkable result in improving the veracity of clinical decision support in medical images. The main objective is to improve the understanding of medical images using Discrete Wavelet Transform technology. DWT mainly uses blending rules involving the average pixel. Discrete wavelet transform has been implemented using fusion technology for medical image fusion. Fusion Power is calculated based on PSNR, MSE, and Total Progression Moment. The result demonstrates the success of the fusion scheme on wavelet transform imaging (MRI) and positron production tomography (PET). Other variants of MRI (magnetic resonance imaging) and PET (positron emission tomography) performed for medical diagnosis. Keywords: Multimodal fusion of medical images, fusion rules, magnetic signs,PET.
{"title":"MULTIMODAL FUSION ANALYSIS OF MEDICAL IMAGES BY DISCRETE WAVELET TRANSFORMATION","authors":"Aynur Jabiyeva Aynur Jabiyeva","doi":"10.55858/ijimh01022022-31","DOIUrl":"https://doi.org/10.55858/ijimh01022022-31","url":null,"abstract":"Medical image fusion is the development of registry and fusion of different pots of one or more imaging modalities in order to improve image value and reduce uncertainty and concern, to improve the applicability of the medical image for clinical opinion or the evaluation of medical care. difficulties. Multimodal medical image fusion algorithms and devices have achieved a remarkable result in improving the veracity of clinical decision support in medical images. The main objective is to improve the understanding of medical images using Discrete Wavelet Transform technology. DWT mainly uses blending rules involving the average pixel. Discrete wavelet transform has been implemented using fusion technology for medical image fusion.\u0000Fusion Power is calculated based on PSNR, MSE, and Total Progression Moment. The result demonstrates the success of the fusion scheme on wavelet transform imaging (MRI) and positron production tomography (PET). Other variants of MRI (magnetic resonance imaging) and PET (positron emission tomography) performed for medical diagnosis.\u0000Keywords: Multimodal fusion of medical images, fusion rules, magnetic signs,PET.","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124152335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction Tethered cord is a term for several different conditions. Common to all conditions of the tethered cord is that the movement of the spinal cord is limited at its base. During daily activities, the spinal cord can not move up and down inside the spinal canal, retreating against the restriction. Withdrawal of the spinal cord if minimal is unlikely to cause damage. In severe cases, the pressure can permanently injure the spinal cord. This functional disorder can be congenital (present at birth, the result of developmental malformations) or it can be acquired (arise later in life). Congenital attachment is usually detected in childhood, but not always. In some cases, congenital malformation is not detected, or properly diagnosed, until adulthood. Tethered Cord Syndrome is relatively rare in adults. Methods and materials We present a 2-year-old child, who has frequent urinary tract infections since infancy. Examined by a neurologist from our Clinic at 2 years of age with the presence of spasticity of the lower extremities and pes eqvinovarus on the right leg. Results Contrast-enhanced magnetic resonance imaging (MRI) diagnosis and consultation with a neurosurgeon are recommended. Conclusion The most common symptoms of this disease in children are lesions of the lower back, fatty tumors of the lower back, skin discoloration of the lower back, back pain, worsened by activity and relieved with rest, leg pain, especially in the back of legs , leg numbness, difficulty walking, deformities of the legs, scoliosis of the spine. If tethered cord sy is later diagnosed it can lead to loss of bladder and colon control. MRI is used for diagnosis. Early surgery is recommended in children to prevent further neurological deterioration. Keywords: Thetered cord, spinal cord, medulla spinalis
{"title":"TETHERED CORD SYNDROME-CASE PRESENTATION","authors":"Danilo Nonkulovski, Filip Duma, Aspazija Sofijanova Danilo Nonkulovski, Filip Duma, Aspazija Sofijanov, Ilija Kirovski, Ivona Jovanovska, Tafije Daci Rexhepi Ilija Kirovski, Ivona Jovanovska, Tafije Daci Rexh, Tanja Ignatovska, Milkica Pasoska Tanja Ignatovska, Milkica Pasoska","doi":"10.55858/ijimh01022022-22","DOIUrl":"https://doi.org/10.55858/ijimh01022022-22","url":null,"abstract":"Introduction\u0000Tethered cord is a term for several different conditions. Common to all conditions of the tethered cord is that the movement of the spinal cord is limited at its base. During daily activities, the spinal cord can not move up and down inside the spinal canal, retreating against the restriction. Withdrawal of the spinal cord if minimal is unlikely to cause damage. In severe cases, the pressure can permanently injure the spinal cord.\u0000This functional disorder can be congenital (present at birth, the result of developmental malformations) or it can be acquired (arise later in life). Congenital attachment is usually detected in childhood, but not always. In some cases, congenital malformation is not detected, or properly diagnosed, until adulthood. Tethered Cord Syndrome is relatively rare in adults.\u0000\u0000Methods and materials\u0000We present a 2-year-old child, who has frequent urinary tract infections since infancy. Examined by a neurologist from our Clinic at 2 years of age with the presence of spasticity of the lower extremities and pes eqvinovarus on the right leg.\u0000\u0000Results \u0000Contrast-enhanced magnetic resonance imaging (MRI) diagnosis and consultation with a neurosurgeon are recommended.\u0000\u0000Conclusion\u0000The most common symptoms of this disease in children are lesions of the lower back, fatty tumors of the lower back, skin discoloration of the lower back, back pain, worsened by activity and relieved with rest, leg pain, especially in the back of legs , leg numbness, difficulty walking, deformities of the legs, scoliosis of the spine. If tethered cord sy is later diagnosed it can lead to loss of bladder and colon control. MRI is used for diagnosis. Early surgery is recommended in children to prevent further neurological deterioration.\u0000Keywords: Thetered cord, spinal cord, medulla spinalis","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115141844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There are different biological treatments for psoriasis and one of these treatments is adalimumab. Here we want to present a case with psoriasis and Duchenne muscular dystrophy treated with adalimumab. A 23-year-old male patient with psoriasis and Duchenne muscular dystrophy applied to our dermatology clinic. At the sixth week control of the patient we achieved PASI 90 response. Duchenne muscular dystrophy is a rare disease and its coexistence with psoriasis is a very rare status. No similar case report was found in the literature. We wanted to present both this rare status and psoriasis progression under adalimumab treatment. Keywords: psoriasis, adalimumab, Duchenne muscular dystrophy
{"title":"ADALİMUMAB: USAGE İN A CASE WİTH PSORİASİS AND DUCHENNE MUSCULAR DYSTROPHY","authors":"Melis Gönülal Melis Gönülal, Didem Didar Balcı Didem Didar Balcı","doi":"10.55858/ijimh01012022-04","DOIUrl":"https://doi.org/10.55858/ijimh01012022-04","url":null,"abstract":"There are different biological treatments for psoriasis and one of these treatments is adalimumab. Here we want to present a case with psoriasis and Duchenne muscular dystrophy treated with adalimumab. A 23-year-old male patient with psoriasis and Duchenne muscular dystrophy applied to our dermatology clinic. At the sixth week control of the patient we achieved PASI 90 response.\u0000Duchenne muscular dystrophy is a rare disease and its coexistence with psoriasis is a very rare status. No similar case report was found in the literature. We wanted to present both this rare status and psoriasis progression under adalimumab treatment. \u0000Keywords: psoriasis, adalimumab, Duchenne muscular dystrophy","PeriodicalId":204122,"journal":{"name":"INTERNATIONAL JOURNAL OF INNOVATIVE MEDICINE & HEALTHCARE","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122890368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：