Awais Amjad Hira Aslam, Khurram, Mateen Akram Muhammad, 2. P. M. Rana Muhammad Umar Jameel, Aiman Farogh Anjum Aneeqa Nasir Qureshi, Saba Izhar Fawad, Hameed, Muhammad Ammar, Maham Qazi, Abrar ul, Hassan Pirzada, Consultant Nephrologist
Introduction: One persistent complication of chronic kidney disease is secondary hyperparathyroidism. Early diagnosis of this disease will reduce morbidity in patients undergoing hemodialysis. Aims & Objectives: To determine the prevalence of secondary hyperparathyroidism in chronic kidney disease patients at National Institute of Kidney Diseases, SZH Lahore. Place and Duration of Study: A cross sectional study was conducted at Nephrology Department of Shaikh Zayed Hospital (SZH) Lahore after getting approval from Institutional Review Board of National Health Research Complex (NHRC). It was conducted from September 2023 to November 2023 &140 hemo-dialysis patients were selected. Material & Methods: We measured serum parathyroid hormone, hemoglobin and other variables, at Biochemistry laboratory of Sheikh Zayed Hospital, in 140 hemodialysis patients. Serum samples were measured for PTH levels using ELISA method. The data was analyzed using SPSS version 20.P value ? 0.05 was considered significant. Results: Fifteen patients had secondary hyperparathyroidism out of 140 hemodialysis patients. Hyperparathyroidism was observed in 10.71 % of the patients. Hyperparathyroidism patients had significantly low calcium, hemoglobin levels & higher phosphate levels. Conclusion: The prevalence of secondary hyperparathyroidism is low at 10.71% of patients undergoing hemodialysis at National Institute of Kidney Disease, SZH Lahore.
{"title":"Prevalence of Secondary Hyperparathyroidism in Hemo- Dialysis Patients","authors":"Awais Amjad Hira Aslam, Khurram, Mateen Akram Muhammad, 2. P. M. Rana Muhammad Umar Jameel, Aiman Farogh Anjum Aneeqa Nasir Qureshi, Saba Izhar Fawad, Hameed, Muhammad Ammar, Maham Qazi, Abrar ul, Hassan Pirzada, Consultant Nephrologist","doi":"10.47489/szmc.v38i1.420","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.420","url":null,"abstract":"Introduction: One persistent complication of chronic kidney disease is secondary hyperparathyroidism. Early diagnosis of this disease will reduce morbidity in patients undergoing hemodialysis.\u0000Aims & Objectives: To determine the prevalence of secondary hyperparathyroidism in chronic kidney disease patients at National Institute of Kidney Diseases, SZH Lahore.\u0000Place and Duration of Study: A cross sectional study was conducted at Nephrology Department of Shaikh Zayed Hospital (SZH) Lahore after getting approval from Institutional Review Board of National Health Research Complex (NHRC). It was conducted from September 2023 to November 2023 &140 hemo-dialysis patients were selected.\u0000Material & Methods: We measured serum parathyroid hormone, hemoglobin and other variables, at Biochemistry laboratory of Sheikh Zayed Hospital, in 140 hemodialysis patients. Serum samples were measured for PTH levels using ELISA method. The data was analyzed using SPSS version 20.P value ? 0.05 was considered significant.\u0000Results: Fifteen patients had secondary hyperparathyroidism out of 140 hemodialysis patients. Hyperparathyroidism was observed in 10.71 % of the patients. Hyperparathyroidism patients had significantly low calcium, hemoglobin levels & higher phosphate levels.\u0000Conclusion: The prevalence of secondary hyperparathyroidism is low at 10.71% of patients undergoing hemodialysis at National Institute of Kidney Disease, SZH Lahore.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"92 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139683463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ammara Mushtaq Khan, Sughra Zulfiqar, Amna Saleem, Fahim Ahmed Subhani, Ammara Ayub, Tahira Khurram
Introduction: Iron deficiency anemia (IDA) is a significant public health issue in Pakistan, affecting up to 63% of children, as revealed by the Pakistan National Nutritional Survey 2018. While oral iron remains the primary choice, challenges in compliance have led to the consideration of intravenous (IV) iron therapy, particularly iron sucrose. The study discusses the safety and efficacy of IV iron therapy in Pakistani children and aims to broaden our understanding of treating IDA in resource-constrained regions. Aims & Objectives: To determine the average hemoglobin (Hb) increase in iron-deficient-anemic children aged 01 to 12 years after treatment with intravenous iron sucrose. Place and Duration of Study: A quasi-experimental study was undertaken at Fauji Foundation Hospital in Rawalpindi, spanning from September 2021 to September 2022. Material & Methods: The study focused on a cohort of pediatric patients aged between 1 and 12 years, all of whom were diagnosed with iron deficiency anemia and had previously encountered ineffective outcomes with oral iron therapy. In this investigation, the patients received treatment involving intravenous iron sucrose. Subsequently, their progress was diligently monitored after a period of 8 weeks. Improvement in hemoglobin level was assessed at the end of treatment to evaluate its efficacy.Data processing and statistical analysis were carried out using SPSS version 23,p-value of <0.05 indicated statistical significance. Results: Out of 150 study cases, 96 (64.0 %) were male, while 54 (36.0 %) were female. The mean age of our study cases was 05 ± 2.3 years of these 150 study cases, 74 (49.3 %) belonged to rural areas, and 76 (50.7 %) belonged to urban areas. Poor socioeconomic status was noted in 97 (64.7 %), and 53 (35.3%) were middle-income. A family history of iron deficiency anaemia was recorded in 16 (10.7%). Iron deficiency due to dietary iron insufficiency was reported in 67 (44.7%), Total Parentral Nutrition (TPN) dependencywas seen in 61 (40.7%) and 22 (14.7%) had chronic gastritis. The mean baseline (pretreatment) haemoglobin level was 7.71 ± 0.63 g/dl, while the mean post-treatment haemoglobin level was 10.68 ± 0.60 g / dl (p = 0.001). Conclusion: After intravenous iron sucrose, we noted a significant rise in paediatric patients' hemoglobin levels, emphasizing its effectiveness and safety. Statistically, we found correlations with age, family history, and causes. Healthcare practitioners should consider injectable iron treatments for better results and reduced health issues in this group.
{"title":"Mean Rise in Hemoglobin After Intravenous Iron Therapy in Children with Iron Deficiency Anemia","authors":"Ammara Mushtaq Khan, Sughra Zulfiqar, Amna Saleem, Fahim Ahmed Subhani, Ammara Ayub, Tahira Khurram","doi":"10.47489/szmc.v38i1.414","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.414","url":null,"abstract":"Introduction: Iron deficiency anemia (IDA) is a significant public health issue in Pakistan, affecting up to 63% of children, as revealed by the Pakistan National Nutritional Survey 2018. While oral iron remains the primary choice, challenges in compliance have led to the consideration of intravenous (IV) iron therapy, particularly iron sucrose. The study discusses the safety and efficacy of IV iron therapy in Pakistani children and aims to broaden our understanding of treating IDA in resource-constrained regions.\u0000Aims & Objectives: To determine the average hemoglobin (Hb) increase in iron-deficient-anemic children aged 01 to 12 years after treatment with intravenous iron sucrose.\u0000Place and Duration of Study: A quasi-experimental study was undertaken at Fauji Foundation Hospital in Rawalpindi, spanning from September 2021 to September 2022.\u0000Material & Methods: The study focused on a cohort of pediatric patients aged between 1 and 12 years, all of whom were diagnosed with iron deficiency anemia and had previously encountered ineffective outcomes with oral iron therapy. In this investigation, the patients received treatment involving intravenous iron sucrose. Subsequently, their progress was diligently monitored after a period of 8 weeks. Improvement in hemoglobin level was assessed at the end of treatment to evaluate its efficacy.Data processing and statistical analysis were carried out using SPSS version 23,p-value of <0.05 indicated statistical significance.\u0000Results: Out of 150 study cases, 96 (64.0 %) were male, while 54 (36.0 %) were female. The mean age of our study cases was 05 ± 2.3 years of these 150 study cases, 74 (49.3 %) belonged to rural areas, and 76 (50.7 %) belonged to urban areas. Poor socioeconomic status was noted in 97 (64.7 %), and 53 (35.3%) were middle-income. A family history of iron deficiency anaemia was recorded in 16 (10.7%). Iron deficiency due to dietary iron insufficiency was reported in 67 (44.7%), Total Parentral Nutrition (TPN) dependencywas seen in 61 (40.7%) and 22 (14.7%) had chronic gastritis. The mean baseline (pretreatment) haemoglobin level was 7.71 ± 0.63 g/dl, while the mean post-treatment haemoglobin level was 10.68 ± 0.60 g / dl (p = 0.001).\u0000Conclusion: After intravenous iron sucrose, we noted a significant rise in paediatric patients' hemoglobin levels, emphasizing its effectiveness and safety. Statistically, we found correlations with age, family history, and causes. Healthcare practitioners should consider injectable iron treatments for better results and reduced health issues in this group.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139869988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ammara Mushtaq Khan, Sughra Zulfiqar, Amna Saleem, Fahim Ahmed Subhani, Ammara Ayub, Tahira Khurram
Introduction: Iron deficiency anemia (IDA) is a significant public health issue in Pakistan, affecting up to 63% of children, as revealed by the Pakistan National Nutritional Survey 2018. While oral iron remains the primary choice, challenges in compliance have led to the consideration of intravenous (IV) iron therapy, particularly iron sucrose. The study discusses the safety and efficacy of IV iron therapy in Pakistani children and aims to broaden our understanding of treating IDA in resource-constrained regions. Aims & Objectives: To determine the average hemoglobin (Hb) increase in iron-deficient-anemic children aged 01 to 12 years after treatment with intravenous iron sucrose. Place and Duration of Study: A quasi-experimental study was undertaken at Fauji Foundation Hospital in Rawalpindi, spanning from September 2021 to September 2022. Material & Methods: The study focused on a cohort of pediatric patients aged between 1 and 12 years, all of whom were diagnosed with iron deficiency anemia and had previously encountered ineffective outcomes with oral iron therapy. In this investigation, the patients received treatment involving intravenous iron sucrose. Subsequently, their progress was diligently monitored after a period of 8 weeks. Improvement in hemoglobin level was assessed at the end of treatment to evaluate its efficacy.Data processing and statistical analysis were carried out using SPSS version 23,p-value of <0.05 indicated statistical significance. Results: Out of 150 study cases, 96 (64.0 %) were male, while 54 (36.0 %) were female. The mean age of our study cases was 05 ± 2.3 years of these 150 study cases, 74 (49.3 %) belonged to rural areas, and 76 (50.7 %) belonged to urban areas. Poor socioeconomic status was noted in 97 (64.7 %), and 53 (35.3%) were middle-income. A family history of iron deficiency anaemia was recorded in 16 (10.7%). Iron deficiency due to dietary iron insufficiency was reported in 67 (44.7%), Total Parentral Nutrition (TPN) dependencywas seen in 61 (40.7%) and 22 (14.7%) had chronic gastritis. The mean baseline (pretreatment) haemoglobin level was 7.71 ± 0.63 g/dl, while the mean post-treatment haemoglobin level was 10.68 ± 0.60 g / dl (p = 0.001). Conclusion: After intravenous iron sucrose, we noted a significant rise in paediatric patients' hemoglobin levels, emphasizing its effectiveness and safety. Statistically, we found correlations with age, family history, and causes. Healthcare practitioners should consider injectable iron treatments for better results and reduced health issues in this group.
{"title":"Mean Rise in Hemoglobin After Intravenous Iron Therapy in Children with Iron Deficiency Anemia","authors":"Ammara Mushtaq Khan, Sughra Zulfiqar, Amna Saleem, Fahim Ahmed Subhani, Ammara Ayub, Tahira Khurram","doi":"10.47489/szmc.v38i1.414","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.414","url":null,"abstract":"Introduction: Iron deficiency anemia (IDA) is a significant public health issue in Pakistan, affecting up to 63% of children, as revealed by the Pakistan National Nutritional Survey 2018. While oral iron remains the primary choice, challenges in compliance have led to the consideration of intravenous (IV) iron therapy, particularly iron sucrose. The study discusses the safety and efficacy of IV iron therapy in Pakistani children and aims to broaden our understanding of treating IDA in resource-constrained regions.\u0000Aims & Objectives: To determine the average hemoglobin (Hb) increase in iron-deficient-anemic children aged 01 to 12 years after treatment with intravenous iron sucrose.\u0000Place and Duration of Study: A quasi-experimental study was undertaken at Fauji Foundation Hospital in Rawalpindi, spanning from September 2021 to September 2022.\u0000Material & Methods: The study focused on a cohort of pediatric patients aged between 1 and 12 years, all of whom were diagnosed with iron deficiency anemia and had previously encountered ineffective outcomes with oral iron therapy. In this investigation, the patients received treatment involving intravenous iron sucrose. Subsequently, their progress was diligently monitored after a period of 8 weeks. Improvement in hemoglobin level was assessed at the end of treatment to evaluate its efficacy.Data processing and statistical analysis were carried out using SPSS version 23,p-value of <0.05 indicated statistical significance.\u0000Results: Out of 150 study cases, 96 (64.0 %) were male, while 54 (36.0 %) were female. The mean age of our study cases was 05 ± 2.3 years of these 150 study cases, 74 (49.3 %) belonged to rural areas, and 76 (50.7 %) belonged to urban areas. Poor socioeconomic status was noted in 97 (64.7 %), and 53 (35.3%) were middle-income. A family history of iron deficiency anaemia was recorded in 16 (10.7%). Iron deficiency due to dietary iron insufficiency was reported in 67 (44.7%), Total Parentral Nutrition (TPN) dependencywas seen in 61 (40.7%) and 22 (14.7%) had chronic gastritis. The mean baseline (pretreatment) haemoglobin level was 7.71 ± 0.63 g/dl, while the mean post-treatment haemoglobin level was 10.68 ± 0.60 g / dl (p = 0.001).\u0000Conclusion: After intravenous iron sucrose, we noted a significant rise in paediatric patients' hemoglobin levels, emphasizing its effectiveness and safety. Statistically, we found correlations with age, family history, and causes. Healthcare practitioners should consider injectable iron treatments for better results and reduced health issues in this group.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"121 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139810093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Human Rotavirus Virus (HRV) is amongst the common enteric viral diarrheal diseases that indirectly or directly influence school-going children in low-income countries. Inadequate information exists on the presence of rotavirus, with reference to drinking water supplies of primary schools in Sindh, Pakistan. Aims & Objectives: We estimated the risk of rotavirus-associated diarrhea through drinking water. The study further compared the HRV-associated risk of diarrheal disease by a type of water source. Place and Duration of Study: A cross-sectional survey was conducted in ten representative districts of Sindh from February 2022 to December 2022. The samples for drinking water were collected from primary schools of ten representative districts of Sindh. This study was a part of the WASH Project funded by USAID (USPCASW Seed Grant P-II) Material & Methods: We selected 425 samples of drinking water from primary schools based on pre-defined selection criteria. We used a Quantitative Microbial Risk Analysis using indicator organisms, i.e., E. coli, to predict the possible health risks of rotavirus. Data was entered and analyzed on SPSS version 26. The graphs were developed using Arc GIS version 3. Morbidity and mortality were predicted using the Quantitative Microbial Risk Assessment (QAMRA) model. Results: Our data revealed that the highest daily risk of HRV-associated diarrhea amongst school children was 11 per 10,000 schoolchildren, resulting in 8.4% annual risk, and the minimum risk was estimated to be 1 in 10,000 children. The burden of diseases for rotavirus using the QAMRA model revealed the severity of the diarrhea. Majority of the children presented with mild diarrhea (86%) followed by severe, and the probability of death was less than <1%. The daily risk of HRV infection was highest (estimated to be 7 and 11%) in pupils of Southern Sindh, with an annual risk of 17.4% to 40%. Conclusion: Our study concluded that the children in the primary schools of Sindh were exposed to poor drinking water quality. The surface water source poses the highest risk of HRV-related diarrhea to school children. Thus, it is highly recommended that point-of-use drinking water treatment systems be adopted. The water sanitation and hygiene (WASH) resources are interlinked, so each resource impacts the other; hence, schools urgently need to invest in providing adequate WASH facilities to stop enteric virus transmission through drinking water sources.
{"title":"Estimation of Rotavirus Associated Diarrheal Disease Burden Amongst Primary School Children of Sindh","authors":"Jamil Ahmed, Umer Saeed, Asima Ayyub, Zoofishan Imran, Faheem Mahmood, Muhammad Irfan","doi":"10.47489/szmc.v38i1.388","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.388","url":null,"abstract":"Introduction: Human Rotavirus Virus (HRV) is amongst the common enteric viral diarrheal diseases that indirectly or directly influence school-going children in low-income countries. Inadequate information exists on the presence of rotavirus, with reference to drinking water supplies of primary schools in Sindh, Pakistan.\u0000Aims & Objectives: We estimated the risk of rotavirus-associated diarrhea through drinking water. The study further compared the HRV-associated risk of diarrheal disease by a type of water source.\u0000Place and Duration of Study: A cross-sectional survey was conducted in ten representative districts of Sindh from February 2022 to December 2022. The samples for drinking water were collected from primary schools of ten representative districts of Sindh. This study was a part of the WASH Project funded by USAID (USPCASW Seed Grant P-II)\u0000Material & Methods: We selected 425 samples of drinking water from primary schools based on pre-defined selection criteria. We used a Quantitative Microbial Risk Analysis using indicator organisms, i.e., E. coli, to predict the possible health risks of rotavirus. Data was entered and analyzed on SPSS version 26. The graphs were developed using Arc GIS version 3. Morbidity and mortality were predicted using the Quantitative Microbial Risk Assessment (QAMRA) model. Results: Our data revealed that the highest daily risk of HRV-associated diarrhea amongst school children was 11 per 10,000 schoolchildren, resulting in 8.4% annual risk, and the minimum risk was estimated to be 1 in 10,000 children. The burden of diseases for rotavirus using the QAMRA model revealed the severity of the diarrhea. Majority of the children presented with mild diarrhea (86%) followed by severe, and the probability of death was less than <1%. The daily risk of HRV infection was highest (estimated to be 7 and 11%) in pupils of Southern Sindh, with an annual risk of 17.4% to 40%.\u0000Conclusion: Our study concluded that the children in the primary schools of Sindh were exposed to poor drinking water quality. The surface water source poses the highest risk of HRV-related diarrhea to school children. Thus, it is highly recommended that point-of-use drinking water treatment systems be adopted. The water sanitation and hygiene (WASH) resources are interlinked, so each resource impacts the other; hence, schools urgently need to invest in providing adequate WASH facilities to stop enteric virus transmission through drinking water sources.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"383 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140471165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Genitourinary/ fecal fistula is an abnormal communication between the genital tract and either the urinary tract or the gastrointestinal tract. Among genitourinary fistulae, most common is the vesicovaginal followed by ureterovaginal fistula. Aims & Objectives: The aim of our study is to determine various causes and types of genitourinary/fecal fistulae and their surgical outcome in our setting. Place and Duration of Study: A descriptive, retrospective cross-sectional study was conducted at Central Park Teaching Hospital Hospital, Department of Obstetrics and Gynaecology from December 2013-December 2021. Material & Methods: Total of 77 patients presented with various types of genitourinary/fecal fistulae during the study period. All details as demographic characteristics, type and cause of fistula, route of repair and surgical outcome were taken on a standardized proforma. All data was entered and analyzed in SPSS version 26 for statistical analysis.p-value of less than 0.05 was regarded as significant. Results: In this study, the age range was from 22 to 62 years with mean age 38.38 + 10.67 years. Mean duration of fistula was computed as 45.47 + 71.31 months with the range of 1 month to 27 years (324 months). Average fistula size was 1.14 + 0.96 cm with the range of 0.25 cm to 3 centimeters. The obstetric causes of fistulae accounted 44% (n=34) while iatrogenic causes were seen in 56% (n=43) of patients. The most common type of fistula was VVF with 53 (69%) patients followed by uretero-vaginal fistula with 08 (10.0%). The least common type of fistula was urethro-vaginal with only 01 (1%) case of 22 years, 05 (7%) patients had RVF and 08 (10%) had vesico-uterine and vesico-cervical fistulae. the overall success rate is 88.3%. Conclusion: The iatrogenic causes of genitourinary/fecal fistulae are more prevalent than obstetric causes. The successful outcome of fistula repair depends on number of previous attempts of repair and outcome of repair worsen with each number of previous attempts.
{"title":"Genitourinary / Fecal Fistulae: Etiology, Types and Surgical Outcomes","authors":"Nayyer Sultana, Tayyaba Majeed, Rana Mohammad Iqbal, Tahseen Haider Kazmi, Mirza Zeeshan Sikandar","doi":"10.47489/szmc.v38i1.443","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.443","url":null,"abstract":"Introduction: Genitourinary/ fecal fistula is an abnormal communication between the genital tract and either the urinary tract or the gastrointestinal tract. Among genitourinary fistulae, most common is the vesicovaginal followed by ureterovaginal fistula.\u0000Aims & Objectives: The aim of our study is to determine various causes and types of genitourinary/fecal fistulae and their surgical outcome in our setting.\u0000Place and Duration of Study: A descriptive, retrospective cross-sectional study was conducted at Central Park Teaching Hospital Hospital, Department of Obstetrics and Gynaecology from December 2013-December 2021.\u0000Material & Methods: Total of 77 patients presented with various types of genitourinary/fecal fistulae during the study period. All details as demographic characteristics, type and cause of fistula, route of repair and surgical outcome were taken on a standardized proforma. All data was entered and analyzed in SPSS version 26 for statistical analysis.p-value of less than 0.05 was regarded as significant.\u0000Results: In this study, the age range was from 22 to 62 years with mean age 38.38 + 10.67 years. Mean duration of fistula was computed as 45.47 + 71.31 months with the range of 1 month to 27 years (324 months). Average fistula size was 1.14 + 0.96 cm with the range of 0.25 cm to 3 centimeters. The obstetric causes of fistulae accounted 44% (n=34) while iatrogenic causes were seen in 56% (n=43) of patients. The most common type of fistula was VVF with 53 (69%) patients followed by uretero-vaginal fistula with 08 (10.0%). The least common type of fistula was urethro-vaginal with only 01 (1%) case of 22 years, 05 (7%) patients had RVF and 08 (10%) had vesico-uterine and vesico-cervical fistulae. the overall success rate is 88.3%.\u0000Conclusion: The iatrogenic causes of genitourinary/fecal fistulae are more prevalent than obstetric causes. The successful outcome of fistula repair depends on number of previous attempts of repair and outcome of repair worsen with each number of previous attempts.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"528 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140476813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. B. Ghafoor, Ghulam Mustafa, Hafiz Shahid Latif, Faiza Sarwar, Muhammad Saleem Leghari, Ali Hasnain
Introduction: Patients of diabetes repeatedly need blood glucose measurement, which may be falsely high due to less water intake and poor hydration of the patients. Aims & Objectives: To determine the effect of water intake or hydration on hematocrit and blood sugar levels in patients with diabetes mellitus. Place and Duration of Study: Pathology Department and Diabetic Center of Sheikh Zayed Hospital, Rahim Yar Khan from January 2023 to July 2023. Material & Methods: It was a cross sectional study conducted in total 75 Type-1 & Type-2 diabetes patients using convenient sampling technique. 5 ml blood samples were drawn before and 20 minutes after oral hydration with 500 ml of oral water in all these patients to determine the effect on hematocrit and blood sugar levels. The data was entered and analyzed on SPSS version 23. Pre and post observations were compared using paired t-test. p-value<0.05 was taken as statistically significant. Results: The mean value for age and BSR (before and after) of study subjects was 46±11 years, 200±97 mg/dl, and 199±94 mg/dl (p=0.8) respectively. While mean value of HCT before hydration was 39±5.8% and after hydration was 38±6.4% (p=0.006). Conclusion: Oral water hydration impacted mean hematocrit values in diabetic patients, significantly lowering them whereas their mean BSR values remained unaffected.
{"title":"Oral Water Hydration May Impact Hematocrit and Blood Sugar Levels in Patients with Diabetes Mellitus","authors":"M. B. Ghafoor, Ghulam Mustafa, Hafiz Shahid Latif, Faiza Sarwar, Muhammad Saleem Leghari, Ali Hasnain","doi":"10.47489/szmc.v38i1.455","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.455","url":null,"abstract":"Introduction: Patients of diabetes repeatedly need blood glucose measurement, which may be falsely high due to less water intake and poor hydration of the patients.\u0000Aims & Objectives: To determine the effect of water intake or hydration on hematocrit and blood sugar levels in patients with diabetes mellitus.\u0000Place and Duration of Study: Pathology Department and Diabetic Center of Sheikh Zayed Hospital, Rahim Yar Khan from January 2023 to July 2023.\u0000Material & Methods: It was a cross sectional study conducted in total 75 Type-1 & Type-2 diabetes patients using convenient sampling technique. 5 ml blood samples were drawn before and 20 minutes after oral hydration with 500 ml of oral water in all these patients to determine the effect on hematocrit and blood sugar levels. The data was entered and analyzed on SPSS version 23. Pre and post observations were compared using paired t-test. p-value<0.05 was taken as statistically significant.\u0000Results: The mean value for age and BSR (before and after) of study subjects was 46±11 years, 200±97 mg/dl, and 199±94 mg/dl (p=0.8) respectively. While mean value of HCT before hydration was 39±5.8% and after hydration was 38±6.4% (p=0.006).\u0000Conclusion: Oral water hydration impacted mean hematocrit values in diabetic patients, significantly lowering them whereas their mean BSR values remained unaffected.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"311 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140473450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junaid Khan Lodhi, Saba Tahir Bukhari, Asma Munaf, Saima Amjad, Muhammad Zubair, Fawad Hameed, Muhammad Shoaib, Muhammad Khurram Jameel
Introduction: LSG is the gold standard sole bariatric procedure for morbid obesity. Small (2cm) and large (6cm) distance of resection margin from pylorus are both being used for neogastric sleeve formation however what is optimal distance remains controversial. Aims & Objectives: To assess excess weight loss results and complication rate with 6cm and 2cm distance of staple line from pylorus during a prolonged surveillance period. Place and Duration of Study: This retrospective cohort study was conducted at Fatima Memorial Hospital from Dec 2013 to Dec 2022 spanning 9 years. Material & Methods: Medical records of 50 morbidly obese patients aged 41- 50 yrs were segregated into two groups of 25 each based on the LSG procedure conducted. Group 1 had LSG with 6cm resection margin from pylorus while group 2 had a staple line distance of 2cm from pylorus for neogastric sleeve formation. The patients were subsequently followed up for excess weight loss (EXL) and BMI at 6 months, 1 year, 2 years, 3 years & 4-year interval. Data was entered and analyzed using SPSS version 21.P value ? 0.05 was considered significant. Results: EWL in Group 1 & 2 was 39.2± 6.77kg & 41.9± 4.35kg at 6 months,73.64± 6.49kg & 71.06± 7.77kg at 1 year, 65.52± 5.53kg & 63.92± 7.07kg at 2 years,58.16± 4.97kg & 57.28± 5.75kg at 3 years and 55.48± 3.39kg & 55.36± 3.72kg for 4 years were, not significant statistically. BMI in group 1 & 2 were 39.47± 5.11 & 35.88± 4.40 at 6 months, 29.22± 2.68 & 29.12± 2.00 at 1 year, 25.44± 1.96 & 24.73± 2.86 at 2 years, 22.84± 1.79 & 22.40±2.20 at 3 years and 21.66± 1.32, 21.67± 1.62 at 4 years were found to be statistically insignificant. Conclusion: With regards to extra weight loss, distance of resection margin from pylorus of 2cm or 6cm have identical effects but the latter has lowest complication incidence after 4 yrs of surveillance. Hence, a distance of 6cm is favoured to ensure safety of LSG for morbidly obese patients. And the findings of this study will help bariatric surgeons to improve technique of LSG in a safe and successful way for effective weight loss in morbidly obese patients.
{"title":"Effects of 6cm versus 2cm Resection Margin from Pylorus on Excess Weight Loss & Complication Rate for Laparo- Scopic Sleeve Gastrectomy: A Nine-Year Experience","authors":"Junaid Khan Lodhi, Saba Tahir Bukhari, Asma Munaf, Saima Amjad, Muhammad Zubair, Fawad Hameed, Muhammad Shoaib, Muhammad Khurram Jameel","doi":"10.47489/szmc.v38i1.422","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.422","url":null,"abstract":"Introduction: LSG is the gold standard sole bariatric procedure for morbid obesity. Small (2cm) and large (6cm) distance of resection margin from pylorus are both being used for neogastric sleeve formation however what is optimal distance remains controversial.\u0000Aims & Objectives: To assess excess weight loss results and complication rate with 6cm and 2cm distance of staple line from pylorus during a prolonged surveillance period.\u0000Place and Duration of Study: This retrospective cohort study was conducted at Fatima Memorial Hospital from Dec 2013 to Dec 2022 spanning 9 years.\u0000Material & Methods: Medical records of 50 morbidly obese patients aged 41- 50 yrs were segregated into two groups of 25 each based on the LSG procedure conducted. Group 1 had LSG with 6cm resection margin from pylorus while group 2 had a staple line distance of 2cm from pylorus for neogastric sleeve formation. The patients were subsequently followed up for excess weight loss (EXL) and BMI at 6 months, 1 year, 2 years, 3 years & 4-year interval. Data was entered and analyzed using SPSS version 21.P value ? 0.05 was considered significant.\u0000Results: EWL in Group 1 & 2 was 39.2± 6.77kg & 41.9± 4.35kg at 6 months,73.64± 6.49kg & 71.06± 7.77kg at 1 year,\u000065.52± 5.53kg & 63.92± 7.07kg at 2 years,58.16± 4.97kg & 57.28± 5.75kg at 3 years and 55.48± 3.39kg & 55.36±\u00003.72kg for 4 years were, not significant statistically. BMI in group 1 & 2 were 39.47± 5.11 & 35.88± 4.40 at 6 months,\u000029.22± 2.68 & 29.12± 2.00 at 1 year, 25.44± 1.96 & 24.73± 2.86 at 2 years, 22.84± 1.79 & 22.40±2.20 at 3 years and\u000021.66± 1.32, 21.67± 1.62 at 4 years were found to be statistically insignificant.\u0000Conclusion: With regards to extra weight loss, distance of resection margin from pylorus of 2cm or 6cm have identical effects but the latter has lowest complication incidence after 4 yrs of surveillance. Hence, a distance of 6cm is favoured to ensure safety of LSG for morbidly obese patients. And the findings of this study will help bariatric surgeons to improve technique of LSG in a safe and successful way for effective weight loss in morbidly obese patients.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"430 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140473035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sadia Iqbal, Muhammad Suhail, Ahmad Haris Suhail, Faiza Rauf, Faiza Shafqat, Maria Illyas
Introduction: Grape seed extract (vitis vinifera) contains antioxidant compounds with ability to prevent aluminium chloride induced hepatotoxicity. Aims & Objectives: To study the effects of grape seed extract on body weight, liver weight and relative tissue weight index in aluminium chloride treated rats. Place and Duration of Study: This experimental study study was conducted at the Animal House of Post Graduate Medical Institute, Lahore. Duration of study was February 2017 to February 2018. Material & Methods: 24 adult, healthy albino rats (male) were divided in to three groups. Group A was given distilled water by gavage (1ml/day), Group B was given aluminium chloride (34mg/kg body weight) and group C was given aluminium chloride plus grape seed extract (34mg/kg and 200 mg/kg body weight) by gavage. Whole treatment continued for 42 days. Statistical Package for Social Sciences (SPSS) version 21 was used for entering and analyzing data.p value of ? 0.05 was considered significant. Results: A significant difference in body weights of Group B and C rats was noted at the end of the study. Mean liver weight was significantly reduced in aluminium treated group and near normal restoration of liver weight was seen in group C receiving grape seed extract. Conclusion: Excessive aluminium chloride exposure led to a reduction in body weight, and liver weight. Grape seed extract being an antioxidant improved these effects.
{"title":"Grape Seed Extract Affects Body Weight, Liver Weight and Relative Tissue Weight Index in Aluminium Chloride Treated Rats","authors":"Sadia Iqbal, Muhammad Suhail, Ahmad Haris Suhail, Faiza Rauf, Faiza Shafqat, Maria Illyas","doi":"10.47489/szmc.v38i1.446","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.446","url":null,"abstract":"Introduction: Grape seed extract (vitis vinifera) contains antioxidant compounds with ability to prevent aluminium chloride induced hepatotoxicity.\u0000Aims & Objectives: To study the effects of grape seed extract on body weight, liver weight and relative tissue weight index in aluminium chloride treated rats.\u0000Place and Duration of Study: This experimental study study was conducted at the Animal House of Post Graduate Medical Institute, Lahore. Duration of study was February 2017 to February 2018.\u0000Material & Methods: 24 adult, healthy albino rats (male) were divided in to three groups. Group A was given distilled water by gavage (1ml/day), Group B was given aluminium chloride (34mg/kg body weight) and group C was given aluminium chloride plus grape seed extract (34mg/kg and 200 mg/kg body weight) by gavage. Whole treatment continued for 42 days. Statistical Package for Social Sciences (SPSS) version 21 was used for entering and analyzing data.p value of ? 0.05 was considered significant.\u0000Results: A significant difference in body weights of Group B and C rats was noted at the end of the study. Mean liver weight was significantly reduced in aluminium treated group and near normal restoration of liver weight was seen in group C receiving grape seed extract.\u0000Conclusion: Excessive aluminium chloride exposure led to a reduction in body weight, and liver weight. Grape seed extract being an antioxidant improved these effects.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"114 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140475548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Femoral fractures are one of the most common issues in the childrens population. Between 6-16 age, there's no strong agreement as to the favored therapy. The therapy of femoral fractures in children has progressively changed towards a more operative tactic within the past two decades. This is because healthcare criteria demand more rapid mobilisation , early discharge and return to family with normal activity. Operative treatment results in short hospitalization and early mobilization, which has psychological, social, educational and economic advantages over conservative treatment. Aims & Objectives: The aim of our study is to determine the frequency of functional outcome with Flynn’s criteria in shaft of femur fracture stabilization with elastic nails in pediatric population between 5 to 10 years of age presenting in a tertiary care hospital. Place and Duration of Study: We conducted ‘Descriptive case series’, in the unit of Orthopedic Surgery, Services Hospital, Lahore from 01-09-2021 to 01-03-2022. Material & Methods: Sixty patients ranging from 5-10 yrs of age, fulfilling the selection criteria were enrolled after the informed consent in the study through the emergency of the Department of Orthopedic Surgery, Services Hospital, Lahore. Surgery for femoral fracture was performed in these patients under general anesthesia by a single surgical team with the assistance of the researcher. The children were followed up at 1, 2, 3, and 6 months. After 6 months, patients were evaluated according to Flynn’s criteria for femoral fracture outcomes with nailing and results were noted as excellent, satisfactory and poor. All the information was recorded in proforma. Data was entered and analyzed using SPSS version. 25.P-value ?0.05 was taken as significant. Results: Out of 60 patients, 23.3 % ( n=14) were in age group of 5-7 years and 76.7 %( n=46) were in age group of 8- 10years and mean age was 8.17±1.01years. 65.0 %( n=39) were male and 35.0 %( n=21) were females. Out of 60 patients, 21.7 % ( n=13) had road traffic accident, 63.3 %( n=38) had history of fall and 15.0 %( n=9) had miscellaneous cause of injury. The frequency of functional outcome according to flynn’s criteria was excellent in 51.7 %( n=31). Conclusion: We concluded that elastic nail is moderately simple to utilize and an compelling treatment for fractures of femoral shaft in legitimately chosen children by applying Flynn's criteria for functional outcome and can further be compared with other treatment modalities.
{"title":"Functional Outcome of Shaft of Femur Fracture Fixation with Elastic Nail in Children Between 05 to 10 Years of Age","authors":"Ammad Ahmed, Zahid Munir, Iftikhar Muhyuddin, Kashif Jamal, Adeel Hamid, Zaigham Habib, Shuja Uddin","doi":"10.47489/szmc.v38i1.398","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.398","url":null,"abstract":"Introduction: Femoral fractures are one of the most common issues in the childrens population. Between 6-16 age, there's no strong agreement as to the favored therapy. The therapy of femoral fractures in children has progressively changed towards a more operative tactic within the past two decades. This is because healthcare criteria demand more rapid mobilisation , early discharge and return to family with normal activity. Operative treatment results in short hospitalization and early mobilization, which has psychological, social, educational and economic advantages over conservative treatment.\u0000Aims & Objectives: The aim of our study is to determine the frequency of functional outcome with Flynn’s criteria in shaft of femur fracture stabilization with elastic nails in pediatric population between 5 to 10 years of age presenting in a tertiary care hospital.\u0000Place and Duration of Study: We conducted ‘Descriptive case series’, in the unit of Orthopedic Surgery, Services Hospital, Lahore from 01-09-2021 to 01-03-2022.\u0000Material & Methods: Sixty patients ranging from 5-10 yrs of age, fulfilling the selection criteria were enrolled after the informed consent in the study through the emergency of the Department of Orthopedic Surgery, Services Hospital, Lahore. Surgery for femoral fracture was performed in these patients under general anesthesia by a single surgical team with the assistance of the researcher. The children were followed up at 1, 2, 3, and 6 months. After 6 months, patients were evaluated according to Flynn’s criteria for femoral fracture outcomes with nailing and results were noted as excellent, satisfactory and poor. All the information was recorded in proforma. Data was entered and analyzed using SPSS version. 25.P-value ?0.05 was taken as significant.\u0000Results: Out of 60 patients, 23.3 % ( n=14) were in age group of 5-7 years and 76.7 %( n=46) were in age group of 8- 10years and mean age was 8.17±1.01years. 65.0 %( n=39) were male and 35.0 %( n=21) were females. Out of 60 patients, 21.7 % ( n=13) had road traffic accident, 63.3 %( n=38) had history of fall and 15.0 %( n=9) had miscellaneous cause of injury. The frequency of functional outcome according to flynn’s criteria was excellent in 51.7 %( n=31).\u0000Conclusion: We concluded that elastic nail is moderately simple to utilize and an compelling treatment for fractures of femoral shaft in legitimately chosen children by applying Flynn's criteria for functional outcome and can further be compared with other treatment modalities.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"98 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140471475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 45-year-old male presented with dull pain in right lumber region. On ultra-sonography, he had severely hydro- nephrotic right kidney with thinned out parenchyma and markedly dilated renal pelvis. On Computed Tomography, there was severe right hydronephrosis and linear calcification on the medial wall of renal pelvis confirmed further on DTPA Renal scan. It was a non-functioning kidney with a normal functioning contra-lateral kidney. The right nephrectomy was performed and a 7 x 7 cm rounded disc like calcification was seen in the medial pelvic wall. Upon histopathology, it was a dystrophic calcification of renal pelvis wall which is a rare finding.
一名 45 岁的男性因右腰部钝痛就诊。在超声声像图上，他的右肾严重肾积水，肾实质变薄，肾盂明显扩张。计算机断层扫描显示，右肾积水严重，肾盂内侧壁有线状钙化，DTPA肾扫描进一步证实了这一点。这是一个无功能的肾脏，而对侧肾脏功能正常。患者接受了右肾切除术，在肾盂内侧壁上发现了一个 7 x 7 厘米的圆形圆盘状钙化物。经组织病理学检查，这是一种罕见的肾盂壁萎缩性钙化。
{"title":"Uretero-Pelvic Junction Obstruction with Calcification of Renal Pelvis Wall","authors":"Arshed Mehmood, Mohammad Taqi, Arif Qayyum","doi":"10.47489/szmc.v38i1.458","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.458","url":null,"abstract":"A 45-year-old male presented with dull pain in right lumber region. On ultra-sonography, he had severely hydro- nephrotic right kidney with thinned out parenchyma and markedly dilated renal pelvis. On Computed Tomography, there was severe right hydronephrosis and linear calcification on the medial wall of renal pelvis confirmed further on DTPA Renal scan. It was a non-functioning kidney with a normal functioning contra-lateral kidney. The right nephrectomy was performed and a 7 x 7 cm rounded disc like calcification was seen in the medial pelvic wall. Upon histopathology, it was a dystrophic calcification of renal pelvis wall which is a rare finding.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"14 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140474828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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