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Analysis of the arterial pressure-volume curve in the three-element windkessel model 三元风帆模型中动脉压力-容积曲线的分析
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378423
A. Cappello, G. Gnudi
A one-step computational procedure is presented for estimating the parameters of the nonlinear three-element windkessel model of the arterial system incorporating a pressure-dependent compliance. Starting from steady-state aortic pressure and flow curves and under generally accepted assumptions, arterial pressure-volume curve, peripheral and characteristic resistances are determined through simple closed-form formulas. The method is applied to both simulated and experimental data and the results are compared with those obtained by an iterative parameter optimization algorithm and possibly with actual values. A major conclusion is that in most cases considered in this study a constant compliance remains an approximation of the compliant element adequate to usual measurement and model errors.<>
提出了一种一步计算方法,用于估计具有压力相关柔度的动脉系统非线性三元风筒模型的参数。从稳定状态的主动脉压力和血流曲线出发,在普遍接受的假设下,通过简单的封闭公式确定动脉压力-容积曲线、外周阻力和特征阻力。将该方法应用于模拟和实验数据,并与迭代参数优化算法得到的结果进行了比较,并可能与实际值进行了比较。一个主要的结论是,在本研究中考虑的大多数情况下,一个恒定的柔度仍然是足以满足通常测量和模型误差的柔度元素的近似值
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引用次数: 3
Reproducibility of time- and frequency-domain indices of heart rate variability assessed after acute myocardial infarction 急性心肌梗死后心率变异性的时域和频域指标的可重复性
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378398
J. Kautzner, R. Xia, K. Hnatkova, A. Staunton, J. Poloniecki, A. Camm, M. Malik
The most frequent clinical use of heart rate variability (HRV) is the identification of those survivors of acute myocardial infarction who are at risk of serious ventricular arrhythmias and/or sudden cardiac death. This study assessed day-to-day reproducibility of the whole spectrum of HRV parameters in survivors of acute phase of myocardial infarction. A 48 hour ambulatory ECG recording was performed in 21 patients on day 5-7 after hospital admission. The study revealed: (a) that under clinically stable conditions the reproducibility of different time-domain and frequency domain indices of HRV is high, and (b) that day-to-day differences in HRV assessment have presumably no effect on its predictive value. At the same time, individual subjects may exhibit marked day-to-day variation of HRV measures, especially those strongly related to the vagal tone. This should be considered when assessing natural course of the disease or the effects of therapeutic interventions.<>
心率变异性(HRV)最常见的临床应用是识别那些急性心肌梗死幸存者,他们有严重室性心律失常和/或心源性猝死的风险。本研究评估了急性期心肌梗死幸存者HRV参数全谱的日常再现性。21例患者于入院后第5-7天进行48小时动态心电图记录。研究表明:(a)在临床稳定的条件下,HRV的不同时域和频域指标的可重复性很高,(b) HRV评估的日常差异可能对其预测值没有影响。同时,个体受试者可能表现出明显的HRV测量的日常变化,特别是那些与迷走神经张力密切相关的测量。在评估疾病的自然过程或治疗干预的效果时,应考虑到这一点。
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引用次数: 1
An automatic neural-network based SVT/VT classification system 基于自动神经网络的SVT/VT分类系统
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378436
D. Thomson, J. Soraghan, T. Durrani
Describes a novel automatic ECG rhythm analysis system for the problem of classifying between normal sinus rhythm (NSR), supraventricular tachycardia (SVT) and ventricular tachycardia (VT). The system comprises two stages-a preprocessing stage and a neural network based classification stage. The preprocessing stage performs feature vector extraction from multi-leaded ECG sources. Key temporal (morphological), spatial (inter-lead) and spectral (frequency) features are used to form the feature vectors. The neural network classifier comprises a multi-layer perceptron trained using the backpropagation algorithm. By fusing features from the spectral and temporal domains, 100% classification is again possible.<>
针对正常窦性心律(NSR)、室上性心动过速(SVT)和室性心动过速(VT)的分类问题,提出了一种新的心电节律自动分析系统。该系统包括两个阶段:预处理阶段和基于神经网络的分类阶段。预处理阶段从多导联心电源中提取特征向量。关键的时间(形态)、空间(引线间)和频谱(频率)特征被用来形成特征向量。神经网络分类器包括一个多层感知器,使用反向传播算法进行训练。通过融合光谱和时域的特征,100%的分类再次成为可能。
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引用次数: 9
High filter imaging of cardiac jets reduces variability: insights from computer modeling 心脏喷射的高滤光成像减少了变异性:来自计算机建模的见解
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378448
E. Cape, M.B. Plecs, A. Lardo, S. Yamachika, C. Reid, J. Gardin
Color Doppler flow mapping has become a widely used technique for detection of regurgitant flow through heart valves. While the technology allows for effective detection of these lesions, quantification of their severity by color Doppler has not been achieved in the clinical setting. This study addressed the hypothesis that elevation of wall filters beyond the levels needed to eliminate structure noise can produce more stable images of jets in the face of previously demonstrated causes of variability.<>
彩色多普勒血流成像已成为广泛应用于心脏瓣膜返流检测的技术。虽然该技术可以有效地检测这些病变,但在临床环境中尚不能通过彩色多普勒来量化其严重程度。该研究提出了一个假设,即在面对先前证明的变异性原因时,超过消除结构噪声所需水平的壁面滤波器的高度可以产生更稳定的射流图像。
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引用次数: 0
CenterSurface model for 3D analysis of regional left ventricular function 用于局部左心室功能三维分析的CenterSurface模型
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378392
E. Bolson, F. Sheehan
The growing availability of surface reconstructions of the heart has increased interest in methods of quantitative analysis of left ventricular (LV) function in 3D. The authors are interested in transferring the advantages of the Centerline method from 2D to 3D. In the CenterSurface method, a medial surface is constructed between reconstructions of the endocardium at end diastole and end systole for wall motion analysis, and between the endocardial and epicardial surfaces for wall thickness. The measurement of motion or wall thickness is made perpendicular to the medial surface. The CenterSurface method will enable one to analyze regional LV wall motion or wall thickening in a uniform manner, independent of patient-to-patient differences in LV size and shape, and using data from any tomographic imaging modality.<>
随着心脏表面重建技术的日益普及,人们对左心室(LV)功能三维定量分析方法的兴趣日益浓厚。作者感兴趣的是将中心线法的优点从二维转移到三维。在CenterSurface方法中,在舒张末期和收缩末期的心内膜重建之间构建一个中间面,用于壁运动分析,在心内膜和心外膜表面之间构建一个中间面,用于壁厚度分析。运动或壁厚的测量垂直于中间表面。CenterSurface方法将使人们能够以统一的方式分析局部左室壁运动或壁增厚,独立于患者间左室大小和形状的差异,并使用来自任何层析成像模式的数据。
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引用次数: 14
Optimal number of averaged frames for noise reduction of ultrasound images 超声图像降噪的最佳平均帧数
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378321
D.F. Vitale, G. Lauria, N. Pelaggi, G. Gerundo, C. Bordini, D. Leosco, C. Rengo, F. Rengo
Data averaging is a common noise reduction practice in several data processing procedures. The authors have used this approach in order to minimize the noise of the ultrasound signals employed in the backscatter analysis of the heart. They assess the optimum number of frames to be used in the averaging routine in order to obtain, in the search for maximum noise reduction, a good compromise between the two opposite criteria: indicating on the one hand the use of the greatest number of frames and the other hand the smallest. Results obtained show that 10 frames averaging allows 50% noise reduction which is equivalent to 90% of the noise reduction obtained by averaging a 4 times greater number of frames.<>
数据平均是几种数据处理过程中常见的降噪方法。作者使用这种方法是为了尽量减少心脏反向散射分析中超声波信号的噪声。他们评估在平均程序中使用的最佳帧数,以便在搜索最大降噪时获得两个相反标准之间的良好折衷:一方面表明使用最大帧数,另一方面表明使用最小帧数。结果表明,10帧平均可以减少50%的噪声,这相当于平均4倍多的帧数所减少的噪声的90%。
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引用次数: 10
ABACUS: a knowledge-based system for the interpretation of arrhythmias in long term ECG ABACUS:一个基于知识的长期心电图心律失常判读系统
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378297
A. Taddei, M. Niccolai, M. Emdin, C. Marchesi
Describes the development of a system for the interpretation of arrhythmias in long term ECG. The architecture consists of a preprocessing module for feature extraction and qualitative description of waveforms, and of a knowledge-based module for diagnostic classification. Medical knowledge for ECG interpretation was represented by rules and objects, while forward chaining was mainly applied for inference. Contextual information related to the patient is also used for diagnosis. Classification of ECG abnormalities is performed in a number of steps by the evaluation of specific rules. Beat types as well as rhythm changes are identified. Performance of beat classification was assessed on selected records.<>
介绍了一种长期心电图心律失常判读系统的研制。该体系结构包括用于特征提取和波形定性描述的预处理模块和用于诊断分类的基于知识的模块。心电解释的医学知识以规则和对象表示,前向链主要用于推理。与患者相关的上下文信息也用于诊断。心电图异常的分类是通过对特定规则的评估在许多步骤中进行的。节拍类型和节奏变化是确定的。在选定的记录上评估节拍分类的性能。
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引用次数: 3
Analysis of regional function and remodeling after thrombolysis: are iterative studies necessary? 溶栓后区域功能和重构分析:是否需要反复研究?
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378324
C. van Eyll, L. Stoleru, W. Hayashida, C. Beauloye, A. Charlier, M. Rousseau, H. Pouleur
The sensitivity of regional wall motion analysis to detect differences between groups one month after myocardial infarction was examined in 53 patients who had received thrombolysis and either had an open vessel or an occluded culprit artery at follow-up. Although the left ventricular volumes were not significantly different between groups, wall motion analysis objectivated differences between the two groups, particularly in the apical area. Similarly, the method evidenced differences between patients treated or not with dipyridamole at the time of reperfusion. Thus, quantitative wall motion analysis obtained from a single time point can be used to analyze pathophysiologic mechanisms or, in pilot studies, to assess the effects of cardioprotective drugs during thrombolysis.<>
对53例接受溶栓治疗,随访时血管通畅或主因动脉闭塞的患者,检测心肌梗死后1个月局部壁运动分析检测组间差异的敏感性。虽然两组间左心室容积无显著差异,但壁运动分析客观地反映了两组间的差异,特别是在心尖区。同样,该方法证明了在再灌注时使用或未使用双嘧达莫的患者之间的差异。因此,从单个时间点获得的定量壁运动分析可用于分析病理生理机制,或在初步研究中评估溶栓过程中心脏保护药物的作用。
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引用次数: 0
Phase locked loop algorithm of longterm ECG induces low frequency oscillations in heart rate variability spectra 长期心电锁相环算法在心率变异性谱中引起低频振荡
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378407
A. Frey, M. Dambacher, K. Theisen
Spectral analysis of heart rare variability (HRV) becomes a promising tool in detecting patients with high risk for sudden death. The calculations are based on the exact evaluation of the QRS distances from beat to beat. Phase locked loop technique should avoid errors from speed variations of the tape recorder. In the authors' investigation they compared spectra of QRS interval tachograms (RR-tachograms) from Holter recordings (ELATEC Holter System) with spectra calculated from directly stored ECG signals. The authors calculated the HRV spectra for healthy volunteers, for patients with proven coronary artery disease and for patients after heart transplantation with very low HRV. The spectral densities from Holter compared with direct recordings showed no differences for healthy volunteers, but for patients with low HRV who showed significant differences in the LF region (0.05-0.15 Hz). Only in the spectra of the Holter ECG system using a phase locked loop technique systemic oscillations around 0.125 Hz were present.<>
心脏罕见变异性(HRV)的频谱分析是一种很有前途的检测猝死高危患者的工具。计算是基于精确的QRS距离的评估从拍到拍。锁相环技术可以避免磁带录音机速度变化带来的误差。在作者的研究中,他们比较了来自动态心电图记录(ELATEC动态心电图系统)的QRS间隔速图(rr -速图)的频谱与直接存储的心电信号计算的频谱。作者计算了健康志愿者、确诊冠状动脉疾病患者和心脏移植后HRV极低患者的HRV谱。与直接记录相比,动态心电图的频谱密度在健康志愿者中没有差异,但在低HRV患者中,低频区(0.05-0.15 Hz)存在显著差异。只有在使用锁相环技术的霍尔特心电图系统的频谱中,才存在0.125 Hz左右的系统振荡。
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引用次数: 2
Discrimination of fast ventricular tachycardia from ventricular fibrillation and slow ventricular tachycardia for an implantable pacer-cardioverter-defibrillator 植入式起搏器-心律转复-除颤器快速室性心动过速与室颤和慢速室性心动过速的区别
Pub Date : 1993-09-05 DOI: 10.1109/CIC.1993.378355
W. Olson, D. Peterson, L. Ruetz, B. Gunderson, M.C. Fang-Yen
Implantable Pacer-Cardioverter-Defibrillators (PCD) sense ventricular electrograms from epicardial or endocardial leads with an auto-adjusting threshold and analyze a recent series of cycle lengths with algorithms to detect ventricular tachycardia (VT) and ventricular fibrillation (VF) for tiered therapies. A new algorithm to detect fast ventricular tachycardia (FVT) in a zone between VT and VF either via VT-type counting or via VF-type counting is described. Gaussian strings of cycle lengths with uniformly distributed means and standard deviations and databases of human tachyarrhythmias are analyzed. Detection algorithm sensitivity, specificity with 95% confidence intervals and the predictive value of a positive test for VF (PVP) are studied as a function of programmable defection parameters. While maintaining 100% VF sensitivity, VF specificity is increased by 20% for FVT via VF thereby safely reducing the number of painful shocks.<>
植入式起搏器-心律转复-除颤器(PCD)通过自动调节阈值来感知心外膜或心内膜导联的心室电图,并通过算法分析最近一系列的周期长度来检测室性心动过速(VT)和心室颤动(VF),以进行分层治疗。本文提出了一种通过VT型计数或VF型计数检测室性心动过速(FVT)的新算法。本文分析了周期长度均匀分布的均值和标准差高斯串和人体速性心律失常的数据库。研究了检测算法的灵敏度、95%置信区间的特异性以及VF (PVP)阳性检测的预测值与可编程缺陷参数的关系。在保持100% VF敏感性的同时,通过VF进行FVT的VF特异性提高了20%,从而安全地减少了痛苦电击的次数
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引用次数: 7
期刊
Proceedings of Computers in Cardiology Conference
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