Dorian Gładysz, B. Grabarek, Marcin Gralewski, Rafał Staszkiewicz, J. Czarniecka
{"title":"Evolution of blood sodium, potassium, and chlorides in patients with steoarthritis of the intervertebral disc compared to healthy volunteers","authors":"Dorian Gładysz, B. Grabarek, Marcin Gralewski, Rafał Staszkiewicz, J. Czarniecka","doi":"10.3390/ecmc2021-11452","DOIUrl":"https://doi.org/10.3390/ecmc2021-11452","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81680756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ricardo G. Teixeira, Alessia Stefanelli, Adhan Pilon, Rebecca Warmers, X. Fontrodona, I. Romero, A. I. Tomaz, A. Brozovic, P. Heffeter, A. Valente
{"title":"Novel silver(I) compounds display strong activity towards resistant ovarian and colorectal cancer cell lines","authors":"Ricardo G. Teixeira, Alessia Stefanelli, Adhan Pilon, Rebecca Warmers, X. Fontrodona, I. Romero, A. I. Tomaz, A. Brozovic, P. Heffeter, A. Valente","doi":"10.3390/ecmc2021-11532","DOIUrl":"https://doi.org/10.3390/ecmc2021-11532","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83902654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Espino, S. Martillanes, J. Rocha-Pimienta, P. Cosme, M. Garrido, J. Delgado-Adámez
{"title":"Chemical composition and biological activity of essential oil from Mentha suaveolens Ehrh. leaves","authors":"J. Espino, S. Martillanes, J. Rocha-Pimienta, P. Cosme, M. Garrido, J. Delgado-Adámez","doi":"10.3390/ecmc2021-11483","DOIUrl":"https://doi.org/10.3390/ecmc2021-11483","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83953977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Fokina, A. Bakhtyukov, K. Derkach, V. Sorokoumov, Lev Klys, A. Shpakov
{"title":"The development of ligands of the thyrotropin receptor transmembrane allosteric site with the activity of antagonists and inverse agonists","authors":"E. Fokina, A. Bakhtyukov, K. Derkach, V. Sorokoumov, Lev Klys, A. Shpakov","doi":"10.3390/ecmc2021-11495","DOIUrl":"https://doi.org/10.3390/ecmc2021-11495","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90108325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesis of thiazolidinedione derivatives and their lipoxygenase inhibition","authors":"Melita Lončarić, M. Molnar, I. Strelec, V. Pavić","doi":"10.3390/ecmc2021-11478","DOIUrl":"https://doi.org/10.3390/ecmc2021-11478","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90549948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liubov V. Krylova, Vasily Otvagin, N. Kuzmina, A. Nyuchev, A. Fedorov, I. Balalaeva
{"title":"Anticancer effect of a chlorin e6 conjugate with vandetanib for combined photodynamic and targeted therapy","authors":"Liubov V. Krylova, Vasily Otvagin, N. Kuzmina, A. Nyuchev, A. Fedorov, I. Balalaeva","doi":"10.3390/ecmc2021-11545","DOIUrl":"https://doi.org/10.3390/ecmc2021-11545","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"156 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75975304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling the therapeutic potential of verbascoside to combat diabetic wound","authors":"B. Sarkar, Rajdeep Saha","doi":"10.3390/ecmc2021-11476","DOIUrl":"https://doi.org/10.3390/ecmc2021-11476","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75530529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heterologous expression, purification and enzymatic activity of aldo-keto reductase 1C4","authors":"Sofija Bekic, E. Petri, A. Ćelić","doi":"10.3390/ecmc2021-11455","DOIUrl":"https://doi.org/10.3390/ecmc2021-11455","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"23 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91491695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The knowledge of carbohydrate molecular structure is essential for understanding various processes in glycobiology. Dermatan sulphate (DS) belongs to the group of glycosaminoglycan (GAG) polysaccharides with biological importance [1]. DS is present in various tissues in higher organisms, e.g. in skin, blood vessels or lungs and plays important roles in various processes, namely intercellular and cell-matrix interactions, cell migrations and morphogenesis [2]. The investigation of DS solution properties and formation of their intermolecular complexes with proteins rely mainly on methods of theoretical chemistry as well as high-resolution NMR spectroscopy. In the present contribution, the results of calculations of molecular geometry of dermatan sulphate by density functional theory (DFT) are discussed and compared with experimental spectroscopic data.
{"title":"Molecular structure of dermatan sulphate tetrasaccharide","authors":"M. Hricovíni","doi":"10.3390/ecmc2021-11456","DOIUrl":"https://doi.org/10.3390/ecmc2021-11456","url":null,"abstract":"The knowledge of carbohydrate molecular structure is essential for understanding various processes in glycobiology. Dermatan sulphate (DS) belongs to the group of glycosaminoglycan (GAG) polysaccharides with biological importance [1]. DS is present in various tissues in higher organisms, e.g. in skin, blood vessels or lungs and plays important roles in various processes, namely intercellular and cell-matrix interactions, cell migrations and morphogenesis [2]. The investigation of DS solution properties and formation of their intermolecular complexes with proteins rely mainly on methods of theoretical chemistry as well as high-resolution NMR spectroscopy. In the present contribution, the results of calculations of molecular geometry of dermatan sulphate by density functional theory (DFT) are discussed and compared with experimental spectroscopic data.","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"1 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91418058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rational design of new antipsychotic virtual derivatives with improved ADMET properties and high binding activity","authors":"Alexia-Maria Lapadat, R. Tamaian","doi":"10.3390/ecmc2021-11479","DOIUrl":"https://doi.org/10.3390/ecmc2021-11479","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83313122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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