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Sensitivity Profile of Carbapenem-Resistant Enterobacteriaceae and Therapeutic Outcome in Children in Syria 叙利亚儿童耐碳青霉烯肠杆菌科的敏感性和治疗结果
Rama Jadeed, I. Anjak
Carbapenem-Resistant Enterobacteriaceae (CRE) threaten public health because the infections they cause carry a high mortality rate and limited treatment options. Few studies focus on these organisms in children compared to the number of the ones carried out on adults. Therefore, the importance of our research is to contribute to broadening our knowledge on the effects of these organisms in children. The objective of our research was to determine each of the following: the sensitivity profile of CRE, available treatment options for dealing with these bacteria, the therapeutic outcome, and the factors affecting this outcome. Our study design was a prospective, single-centre analytical cohort study. Samples were collected from the Children’s University Hospital in Damascus, which conatins 389 beds and 60 incubators. Disk diffusion was used to examine bacterial susceptibility; some samples were tested in BD Phoenix system. Our research examined antibiotics resistance rates, duration to treatment response, and mortality rate. The research sample included 277 samples, 125 of which were resistant to Carbapenem. High resistance to most of the available antibiotics characterized the Carbapenem Resistant Enterobacteriaceae strains. Colistin, Imipenem and Amikacin were the most used antibiotics in our study; one or two antibiotics were used in most cases. Moreover, the mortality rate was 42.4%, and most of the deaths were due to infection itself. The median duration of treatment response was 8.4 days, and the factors were associated with a statistically significant higher mortality rate (age less than one month, the use of certain antibiotics in treatment such as Piperacillin-Tazobactam, and association with respiratory tract infection). Regarding response to treatment, there was no significant difference between Resistant and Non-Resistant Carbapenem Enterobacteriaceae in terms of duration. Enterobacteriaceae resistance to Carbapenems caused a very high mortality rate. Our treatment options were limited; consequently, the introduction of novel antibiotics in our treatment options is required.
碳青霉烯耐药肠杆菌科(CRE)威胁着公众健康,因为它们引起的感染具有高死亡率和有限的治疗选择。与对成人进行的研究数量相比,很少有研究关注儿童体内的这些微生物。因此,我们的研究的重要性在于有助于扩大我们对这些生物体对儿童的影响的认识。我们研究的目的是确定以下每一项:CRE的敏感性、处理这些细菌的可用治疗方案、治疗结果以及影响结果的因素。我们的研究设计是一项前瞻性、单中心分析队列研究。样本是从大马士革儿童大学医院收集的,该医院有389张床位和60个恒温箱。采用纸片扩散法检测细菌药敏;部分样品在BD Phoenix系统中进行了测试。我们的研究考察了抗生素耐药率、治疗反应持续时间和死亡率。研究样本共277份,其中碳青霉烯耐药125份。耐碳青霉烯肠杆菌科菌株对大多数现有抗生素具有高耐药性。粘菌素、亚胺培南和阿米卡星是本研究中使用最多的抗生素;大多数情况下使用一种或两种抗生素。此外,死亡率为42.4%,大多数死亡是由于感染本身。治疗反应的中位持续时间为8.4天,这些因素与具有统计学意义的较高死亡率相关(年龄小于一个月,在治疗中使用某些抗生素,如哌拉西林-他唑巴坦,以及与呼吸道感染相关)。至于对治疗的反应,耐药和非耐药碳青霉烯肠杆菌科在持续时间方面没有显著差异。肠杆菌科对碳青霉烯类的耐药性造成了非常高的死亡率。我们的治疗选择有限;因此,需要在我们的治疗方案中引入新型抗生素。
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引用次数: 1
The Frequency of Fibromyalgia in Patients With Tension-Type Headache 紧张性头痛患者纤维肌痛的发生频率
Yahya Qasim M. Taher, A. Younis, Ali Neamat Sulaiman Alallaf
Fibromyalgia (FM) is a prevailing debilitating disorder that has been documented in patients with tension-type headache (TTH). The goal of this study was to determine the prevalence of fibromyalgia in TTH patients as well as the features of TTH patients with concomitant FM. One hundred patients with TTH and 100 apparently healthy subjects were conjoined in this study. The socio-demographic and headache characteristics of the patients were recorded. Patients with TTH had a considerably higher frequency of FM (34%) when compared to the controls (9%). TTH patients with FM had a substantially older mean age and a higher percentage of female participants than TTH patients without FM. Patients with comorbid fibromyalgia had greater headache frequency (P =0.02), headache intensity (P = 0.003), and higher scores on the HIT-6 (P = 0.004), GAD -7 (P =0.04), and PHQ-9 (p= 0.02), whereas there was no variation between the diseased patients and controls with regards to disease duration. In conclusion, there is a high frequency of FM in patients with TTH. Patients with coexistent FM and TTH tend to have more anxiety and depressive features, more severe headache, greater headache frequency, and when compared to people who do not have fibromyalgia, they are more likely to have a significant headache-related impairment.
纤维肌痛(FM)是一种普遍的衰弱性疾病,已在紧张性头痛(TTH)患者中得到证实。本研究的目的是确定TTH患者纤维肌痛的患病率以及TTH合并FM患者的特征。本研究将100例TTH患者与100例表面健康的受试者相结合。记录患者的社会人口学特征和头痛特征。TTH患者的FM频率(34%)明显高于对照组(9%)。与没有FM的TTH患者相比,有FM的TTH患者的平均年龄要大得多,女性参与者的比例也更高。合并纤维肌痛的患者头痛频率更高(P =0.02),头痛强度更高(P = 0.003),并且在hit6 (P = 0.004)、GAD -7 (P =0.04)和PHQ-9 (P =0.02)上得分更高,而在疾病持续时间方面,患病患者与对照组之间没有差异。综上所述,TTH患者FM发生率较高。FM和TTH共存的患者往往有更多的焦虑和抑郁特征,头痛更严重,头痛频率更高,与没有纤维肌痛的人相比,他们更有可能出现明显的头痛相关损害。
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引用次数: 0
Effects of Local Application of Platelet Rich Fibrin versus Hyaluronic Acid on Postoperative Sequelae After Surgical Removal of Impacted Lower Third Molar 局部应用富血小板纤维蛋白与透明质酸对下颌第三磨牙拔除术后后遗症的影响
I. Marouf, Atalla F. Rejab
Objectives: This study aims to evaluate the effectiveness of local application of platelet rich fibrin and hyaluronic acid on postoperative sequelae after surgical extraction of impacted mandibular third molars. Materials and Methods: The research included a total of 66 healthy patients, from both genders, aged between 19-29 years partially erupted mandibular third molar. All procedures had been done under local anesthesia. Patients randomly divided into three groups. First group platelet rich fibrin and in the second group (Gengigel ® Prof Syringes, Ricerfarma) which contain 0.8% hyaluronic acid were applied in the post extraction socket of impacted lower third molar. In the third control group nothing was placed in the extraction sockets. Postoperative pain, swelling, and trismus were evaluated on the 1st, 3rd, and 7th postoperative days. Results: Hyaluronic acid 0.8% (Gengigel) showed significant reduction in both pain and swelling for the 1st and 3rd postoperative days when compared to the control group. Platelet rich fibrin group revealed a significant lower pain at 1st postoperative day and less swelling at 3rd postoperative day in comparison to the control group. No differences were determined among all groups in maximum mouth opening (trismus). Conclusions: The result of this study showed that both hyaluronic acid and platelet rich fibrin reduced the postoperative pain and swelling. However, the outcome of hyaluronic acid was more satisfied than the platelet rich fibrin in comparison to that of control group after wisdom teeth surgery.
目的:评价富血小板纤维蛋白和透明质酸局部应用治疗下颌阻生第三磨牙拔除术后后遗症的效果。材料与方法:研究对象为66例健康患者,年龄19-29岁,男女不限。所有手术均在局部麻醉下完成。患者随机分为三组。第一组使用富含血小板的纤维蛋白,第二组使用含有0.8%透明质酸的Gengigel®Prof Syringes, Ricerfarma公司产品。在第三个对照组中,拔牙槽内不放置任何东西。术后第1天、第3天和第7天评估术后疼痛、肿胀和牙关。结果:透明质酸0.8% (Gengigel)与对照组相比,术后第1天和第3天疼痛和肿胀均明显减轻。富血小板纤维蛋白组术后第1天疼痛明显减轻,术后第3天肿胀明显减轻。各组间最大开口(牙关)无差异。结论:本研究结果显示透明质酸和富血小板纤维蛋白均能减轻术后疼痛和肿胀。然而,与对照组相比,透明质酸比富血小板纤维蛋白效果更令人满意。
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引用次数: 0
Pharmacokinetic of Flunixin Meglumine in Broiler Chicks by Enzyme-linked Immunosorbent Assay 用酶联免疫吸附法研究氟尼新聚氨胺在肉鸡体内的药动学
Zahraa Alhumdany, Y. Albadrany
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引用次数: 0
Detection of Potential ESBL, Ampc, and Metallo-Beta-Lactamase Producers (MDR-GNB) Through In-vitro Susceptibility Testing of Genitourinary Specimens in a Community-based Pilot Study 基于社区的泌尿生殖系统标本体外药敏检测潜在ESBL、Ampc和金属β -内酰胺酶产生物(MDR-GNB)的试点研究
Dina W. Abed, A. Jusmani, S. Alrifai
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引用次数: 0
Biochemical Changes in Maxillofacial Infection 颌面部感染的生化变化
Taghreed H. Alsadoon, Zainab. G. Saade, Marwa. M. Abd Alrasool, Taif. J. Ghanim, Hussien. A. Khadim
{"title":"Biochemical Changes in Maxillofacial Infection","authors":"Taghreed H. Alsadoon, Zainab. G. Saade, Marwa. M. Abd Alrasool, Taif. J. Ghanim, Hussien. A. Khadim","doi":"10.2991/ahsr.k.211012.028","DOIUrl":"https://doi.org/10.2991/ahsr.k.211012.028","url":null,"abstract":"","PeriodicalId":20538,"journal":{"name":"Proceedings of the 1st International Ninevah Conference on Medical Sciences (INCMS 2021)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89798443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness of Pharmacists & Pharmacy Students About Doping, and the Need for Doping Education in Iraq 伊拉克药剂师和药学学生对兴奋剂的认识及兴奋剂教育的必要性
H. Aldewachi, Aya Raheem, Wafaa Mohammed
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引用次数: 0
COVID-19 Infection Among Hemodialysis Patients in Tikrit City 提克里特市血液透析患者中COVID-19感染
I. Saadoon, Kamal Lateef Hussein
It has been widely documented that hemodialysis patients get a blocked secure response, that might result in a greater prevalence rate of viral diseases, according to Coronavirus epidemic 2019. (Covid -19). The point of this consider was to assess the recurrence of Covid -19 Immunoglobulin G (IgG) antibodies among hemodialysis patients. The current research included 90 hemodialysis patients (50 males and 40 female) who gone to Tikrit Teaching Hospital for the time from starting of December/2020 to the conclusion of May/2021. The Covid -19 -IgG was found in a higher rate in males than that in females (18.89% and 12.22% respectively). Also, non-significant relation was found between age and seropositivity for Covid -19 -IgG antibodies (p ≤ 0.05). Since patients receiving hemodialysis treatment are immunocompromised and can be at risk of infection of Covid -19.
根据2019年冠状病毒疫情,已有广泛记录表明,血液透析患者的安全反应被阻断,这可能导致病毒性疾病的患病率更高。(Covid -19)。本研究的目的是评估血液透析患者中Covid -19免疫球蛋白G (IgG)抗体的复发情况。目前的研究包括从2020年12月初到2021年5月底在提克里特教学医院就诊的90名血液透析患者(50名男性和40名女性)。男性中新冠病毒igg的检出率高于女性(分别为18.89%和12.22%)。年龄与血清Covid -19 igg抗体阳性无显著相关(p≤0.05)。因为接受血液透析治疗的患者免疫功能低下,可能有感染Covid -19的风险。
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引用次数: 0
Assessment of Stroke Knowledge Among a Sample of Iraqi Adults Individuals Attending AL- Sheikh Zayed Hospital in Baghdad City 在巴格达市谢赫扎耶德医院就诊的伊拉克成年人中风知识的评估
M. Q. Baktash, Moatz Majeed Ali, Aqeel Hasan, A. Aziz
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引用次数: 0
Skin Extension for Tan and Bianchi Incision in Pyloromyotomy 幽门肌切开术中Tan、Bianchi切口的皮肤延伸
M. Alani, Sinan Aljarah
Umbilical cord pyloromyotomy for infant hypertrophic pyloric stenosis (IHPS) shows excellent cosmetic results, in up to 30% of cases, be this is because there is a possibility that the point of the skin fold over the muscle does not allow comfortable placement of the hypertrophic pylorus, leading to undesirable serous lacerations. The aim of this study was to evaluate the safety of hysterectomy for IHPS using a modification of the Tan-Bianchi method.
婴儿肥厚性幽门狭窄(IHPS)的脐带幽门切开术显示出良好的美容效果,在高达30%的病例中,这是因为有可能皮肤折叠点在肌肉上不允许舒适地放置肥厚性幽门,导致不良的浆液撕裂伤。本研究的目的是评价采用改良的坦-比安奇法进行子宫切除术治疗IHPS的安全性。
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Proceedings of the 1st International Ninevah Conference on Medical Sciences (INCMS 2021)
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