A. Cherukupalli, S. Parmar, Yuda Shih, A. Butt, Gary K.Yang, Jonathan D. Misskey, York N. Hsiang
{"title":"Influence of internal medicine perioperative consult team on vascular surgical patients","authors":"A. Cherukupalli, S. Parmar, Yuda Shih, A. Butt, Gary K.Yang, Jonathan D. Misskey, York N. Hsiang","doi":"10.15761/vdt.1000188","DOIUrl":"https://doi.org/10.15761/vdt.1000188","url":null,"abstract":"","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123280160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echocardiography and cardiac embolic stroke","authors":"Nguyen Tuan Vu, Le Huu Quynh Trang","doi":"10.15761/vdt.1000180","DOIUrl":"https://doi.org/10.15761/vdt.1000180","url":null,"abstract":"","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123439503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A brain CT scan without contrast revealed on the last slice, a hyperdense serpiginous vessel in the left frontal lobe, ie a “cord sign”, thus suggesting a diagnosis of a thrombosed frontal cortical vein (Figure 1a, arrow). On brain MR imaging on a 3T scan the conventional sequences were normal: T1-weighted-image (T1WI), T2-weightedimage (T2WI), fluidattenuated inversion recovery (FLAIR) and diffusion-weighted imaging (DWI). Susceptibility-weighted imaging (susceptibility-weighted angiography, SWAN sequence) (Figure 1b), showed a dark serpiginous vessel in the area relative to that of the “cord sign” on the non-contrast CT, confirming the diagnosis of thrombosed frontal vein. 3-Dimmensional contrast-enhanced T1WI MRI sequence (CE 3D T1) showed on multiformat reformat (MPR) an intraluminalfilling defect surrounded by contrast in a left frontal vein at the same level (Figure 1c, arrow), suggestive of an intraluminal thrombus.
未做对比的脑部CT扫描在最后一层显示左侧额叶一高密度蛇形血管，即“脊髓征”，提示额叶皮质静脉血栓形成(图1a，箭头)。3T脑MR成像常规序列正常:t1加权图像(T1WI)、t2加权图像(T2WI)、流体衰减反演恢复(FLAIR)和弥散加权成像(DWI)。敏感性加权成像(敏感性加权血管造影，SWAN序列)(图1b)显示，相对于非对比CT上的“脊髓征”，该区域有一深色蛇状血管，证实额静脉血栓形成的诊断。三维增强T1WI MRI序列(CE 3D T1)显示，在相同水平的左侧额静脉，在多格式重组(MPR)上显示一个被造影剂包围的腔内充盈缺损(图1c，箭头)，提示腔内血栓。
{"title":"Clinical and radiological pitfalls in Isolated cortical venous thrombosis. Don’t miss the “last slice”","authors":"M. Boukobza, Edmond Doggo, É. Manchon, J. Laissy","doi":"10.15761/vdt.1000168","DOIUrl":"https://doi.org/10.15761/vdt.1000168","url":null,"abstract":"A brain CT scan without contrast revealed on the last slice, a hyperdense serpiginous vessel in the left frontal lobe, ie a “cord sign”, thus suggesting a diagnosis of a thrombosed frontal cortical vein (Figure 1a, arrow). On brain MR imaging on a 3T scan the conventional sequences were normal: T1-weighted-image (T1WI), T2-weightedimage (T2WI), fluidattenuated inversion recovery (FLAIR) and diffusion-weighted imaging (DWI). Susceptibility-weighted imaging (susceptibility-weighted angiography, SWAN sequence) (Figure 1b), showed a dark serpiginous vessel in the area relative to that of the “cord sign” on the non-contrast CT, confirming the diagnosis of thrombosed frontal vein. 3-Dimmensional contrast-enhanced T1WI MRI sequence (CE 3D T1) showed on multiformat reformat (MPR) an intraluminalfilling defect surrounded by contrast in a left frontal vein at the same level (Figure 1c, arrow), suggestive of an intraluminal thrombus.","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121542672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We focused on the importance of procedure strategy for the planning of treatment in a patient with calcified occlusive abdominal aorta with bilateral renal artery stenosis showing intermittent claudication. A 76-year-old man was admitted to our hospital with acute decompensated heart failure. He had a history of hypertension, dyslipidaemia, chronic kidney disease, smoking habit, heavy alcohol intake, and coronary artery bypass graft surgery 6 years ago. Examination revealed that the abdominal aorta was nearly completely occluded due to a large calcified nodule involving bilateral renal arteries. Because he suffered from bilateral intermittent claudication, we decided to undertake revascularization of the abdominal aorta and left renal artery by endovascular treatment (EVT) in a single session. We aimed to secure disappearance of the pressure gradient, but not full distension of the abdominal aorta. We undertook EVT with balloon-expandable stent in order to maintain superior mesenteric artery flow and to ensure firm dilation of the left renal artery. For the calcified abdominal aorta, we tried to construct bidirectional routes of abdominal aortic blood flow antegradely and retrogradely. Our technique is less invasive than bypass surgery and can be performed safely under local anaesthesia using percutaneous access.
{"title":"A case of endovascular treatment for juxtarenal aortic calcified occlusion with intermittent claudication","authors":"Keisuke Ueno, Y. Shinoda, I. Shiojima, S. Hoshida","doi":"10.15761/VDT.1000173","DOIUrl":"https://doi.org/10.15761/VDT.1000173","url":null,"abstract":"We focused on the importance of procedure strategy for the planning of treatment in a patient with calcified occlusive abdominal aorta with bilateral renal artery stenosis showing intermittent claudication. A 76-year-old man was admitted to our hospital with acute decompensated heart failure. He had a history of hypertension, dyslipidaemia, chronic kidney disease, smoking habit, heavy alcohol intake, and coronary artery bypass graft surgery 6 years ago. Examination revealed that the abdominal aorta was nearly completely occluded due to a large calcified nodule involving bilateral renal arteries. Because he suffered from bilateral intermittent claudication, we decided to undertake revascularization of the abdominal aorta and left renal artery by endovascular treatment (EVT) in a single session. We aimed to secure disappearance of the pressure gradient, but not full distension of the abdominal aorta. We undertook EVT with balloon-expandable stent in order to maintain superior mesenteric artery flow and to ensure firm dilation of the left renal artery. For the calcified abdominal aorta, we tried to construct bidirectional routes of abdominal aortic blood flow antegradely and retrogradely. Our technique is less invasive than bypass surgery and can be performed safely under local anaesthesia using percutaneous access.","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129654737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Matrix Gla-Protein (MGP) is involved in the prevention of arterial calcification. During vitamin K-insufficiency, MGP is produced in its inactive form: dp-ucMGP. Two 3-year intervention studies in the general population have shown that increased vitamin K intake may decrease arterial stiffening, but the difference with placebo became only significant in the third year of treatment. In the present trial we have investigated whether in a pre-selected group of vitamin K-insufficient subjects (men and women) an effect of vitamin K-supplementation may be demonstrated within one year. Methods: A randomized placebo-controlled clinical trial was performed in 243 subjects (40-70 years old) characterized by circulating dp-ucMGP concentrations above the median of the general population. Arterial stiffness was concluded from the carotid-femoral pulse-wave velocity (cfPWV), and other vascular characteristics were measured by echotracking of the common carotid artery. Treatment was performed with either vitamin K (menaquinone-7, MK-7) or placebo for one year. Results: In the total study group, MK-7 induced a significant decrease of both dp-ucMGP and cfPWV. After subdividing by gender, it appeared that the effects were only seen in women, in whom we also found beneficial effects in other vascular characteristics as well as in body weight and BMI. Conclusions : High vitamin K intake decreased age-related vascular stiffening. The effects were most obvious in women with poor vitamin K status and were statistically significant after one year of treatment. In-tima-Media Young’s Modulus
{"title":"Effect of Menaquinone-7 (vitamin K2) on vascular elasticity in healthy subjects: results from a one-year study","authors":"C. Vermeer, H. Vik","doi":"10.15761/VDT.1000179","DOIUrl":"https://doi.org/10.15761/VDT.1000179","url":null,"abstract":"Background: Matrix Gla-Protein (MGP) is involved in the prevention of arterial calcification. During vitamin K-insufficiency, MGP is produced in its inactive form: dp-ucMGP. Two 3-year intervention studies in the general population have shown that increased vitamin K intake may decrease arterial stiffening, but the difference with placebo became only significant in the third year of treatment. In the present trial we have investigated whether in a pre-selected group of vitamin K-insufficient subjects (men and women) an effect of vitamin K-supplementation may be demonstrated within one year. Methods: A randomized placebo-controlled clinical trial was performed in 243 subjects (40-70 years old) characterized by circulating dp-ucMGP concentrations above the median of the general population. Arterial stiffness was concluded from the carotid-femoral pulse-wave velocity (cfPWV), and other vascular characteristics were measured by echotracking of the common carotid artery. Treatment was performed with either vitamin K (menaquinone-7, MK-7) or placebo for one year. Results: In the total study group, MK-7 induced a significant decrease of both dp-ucMGP and cfPWV. After subdividing by gender, it appeared that the effects were only seen in women, in whom we also found beneficial effects in other vascular characteristics as well as in body weight and BMI. Conclusions : High vitamin K intake decreased age-related vascular stiffening. The effects were most obvious in women with poor vitamin K status and were statistically significant after one year of treatment. In-tima-Media Young’s Modulus","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124817466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Calcaianu, U. Crimizade, N. Messas, D. Bresson, J. Wiedemann, O. Roth, M. Kindo, O. Morel, J. Lévy, L. Jacquemin, P. Ohlmann
Background : Balloon aortic valvuloplasty (BAV) might be a life saving procedure in critically advanced aortic stenosis (AS) as a bridge therapy to surgical aortic valve replacement (AVR) or to trans-catheter aortic heart valve (TAVI), by reducing trans-aortic gradient and increasing aortic valve area (AVA). Few is known on the benefit of BAV on cardiac output. Our study proposed to evaluate the hemodynamic changes after BAV by transthoracic echocardiography (TTE). Methods: 30 consecutive patients with AS undergoing BAV were prospectively included between July 2014 and July 2015. Hemodynamic assessment was performed pre- and post-BAV by TTE. Low cardiac output (CO) was defined by a cardiac index (CI) < 2.5 L/min/m 2 . Results: Mean age was 82 ± 8 years; 56.7% were female; mean logistic EuroSCORE I was 31 ± 19 %. 20 patients (67%) had low CO. TTE showed that the patients with low CO improved AVA (from 0.57 ± 0.2 to 1.05 ± 0.5, p=0.043), CI (from 1.9 ± 0.4 to 2.8 ± 1.0 L/min/m 2 , p<0.0001), LVEF (from 31 ± 16 to 38 ± 13%, p=0.006), tend to decrease systolic pulmonary artery pressure (sPAP) (from 52 ± 19 to 43 ± 11 mmHg, p=0.06) and to increase mean arterial pressure (MAP) (from 79 ± 10 to 83 ± 12 mmHg, p=0.046). There was no statistically significant difference in terms of hemodynamic in patients with a normal CO (CI ≥ 2.5 L/min/m 2 ). Conclusion: By increasing AVA, BAV significantly and immediately improve cardiac output especially in patients with low CO at baseline.
{"title":"Immediate benefit of balloon aortic valvuloplasty in severe aortic stenosis: hemodynamic echographic assessment in Intensive Coronary Care Unit","authors":"M. Calcaianu, U. Crimizade, N. Messas, D. Bresson, J. Wiedemann, O. Roth, M. Kindo, O. Morel, J. Lévy, L. Jacquemin, P. Ohlmann","doi":"10.15761/vdt.1000154","DOIUrl":"https://doi.org/10.15761/vdt.1000154","url":null,"abstract":"Background : Balloon aortic valvuloplasty (BAV) might be a life saving procedure in critically advanced aortic stenosis (AS) as a bridge therapy to surgical aortic valve replacement (AVR) or to trans-catheter aortic heart valve (TAVI), by reducing trans-aortic gradient and increasing aortic valve area (AVA). Few is known on the benefit of BAV on cardiac output. Our study proposed to evaluate the hemodynamic changes after BAV by transthoracic echocardiography (TTE). Methods: 30 consecutive patients with AS undergoing BAV were prospectively included between July 2014 and July 2015. Hemodynamic assessment was performed pre- and post-BAV by TTE. Low cardiac output (CO) was defined by a cardiac index (CI) < 2.5 L/min/m 2 . Results: Mean age was 82 ± 8 years; 56.7% were female; mean logistic EuroSCORE I was 31 ± 19 %. 20 patients (67%) had low CO. TTE showed that the patients with low CO improved AVA (from 0.57 ± 0.2 to 1.05 ± 0.5, p=0.043), CI (from 1.9 ± 0.4 to 2.8 ± 1.0 L/min/m 2 , p<0.0001), LVEF (from 31 ± 16 to 38 ± 13%, p=0.006), tend to decrease systolic pulmonary artery pressure (sPAP) (from 52 ± 19 to 43 ± 11 mmHg, p=0.06) and to increase mean arterial pressure (MAP) (from 79 ± 10 to 83 ± 12 mmHg, p=0.046). There was no statistically significant difference in terms of hemodynamic in patients with a normal CO (CI ≥ 2.5 L/min/m 2 ). Conclusion: By increasing AVA, BAV significantly and immediately improve cardiac output especially in patients with low CO at baseline.","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122022566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atherosclerosis is a cardiovascular disease marked by chronic inflammation. The disease is intimately related to the accumulation of fatty acids in the tunica intima of medium and large caliber arteries. The development of the disease respond to alteration of the vascular and immune system homeostasis. The inflammatory process is aggravated by the action of immune cells. The diagnosis of the disease is invasive in most cases. Thus, new diagnostic and therapeutic techniques are required and could increase the quality of life of atherosclerotic patients. The eNOS gene has been indicated as an efficient biomarker of cardiovascular diseases, including atherosclerosis, stroke and myocardium infarction. The eNOS gene and the protein it encodes control the production of nitric oxide. This compound takes part in a large variety of biological functions and its action is crucial for the protection of arteries against damage. Here, an in-silico approach was used to design two small active peptides as a way to stabilize eNOS and guarantee its normal level of function regarding the production of nitric oxide. We hypothesize that the use of designed peptide would lead to an efficient therapy and with less or none side effect to atherosclerotic patients, as a substitution of statins therapy, such as atorvastatin. For future perspective, an assay of the modulating peptides is being designed to be tested in vitro and in vivo in order to be possibly used as a new therapeutic agent.
{"title":"A modulator peptide stabilize the eNOS protein similar to atorvastatin in atherosclerosis patients","authors":"K. S. Freitas e Silva","doi":"10.15761/vdt.1000166","DOIUrl":"https://doi.org/10.15761/vdt.1000166","url":null,"abstract":"Atherosclerosis is a cardiovascular disease marked by chronic inflammation. The disease is intimately related to the accumulation of fatty acids in the tunica intima of medium and large caliber arteries. The development of the disease respond to alteration of the vascular and immune system homeostasis. The inflammatory process is aggravated by the action of immune cells. The diagnosis of the disease is invasive in most cases. Thus, new diagnostic and therapeutic techniques are required and could increase the quality of life of atherosclerotic patients. The eNOS gene has been indicated as an efficient biomarker of cardiovascular diseases, including atherosclerosis, stroke and myocardium infarction. The eNOS gene and the protein it encodes control the production of nitric oxide. This compound takes part in a large variety of biological functions and its action is crucial for the protection of arteries against damage. Here, an in-silico approach was used to design two small active peptides as a way to stabilize eNOS and guarantee its normal level of function regarding the production of nitric oxide. We hypothesize that the use of designed peptide would lead to an efficient therapy and with less or none side effect to atherosclerotic patients, as a substitution of statins therapy, such as atorvastatin. For future perspective, an assay of the modulating peptides is being designed to be tested in vitro and in vivo in order to be possibly used as a new therapeutic agent.","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125622070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of pulmonary embolism. A deep vein thrombosis diagnosis due to uterine myoma compressing the inferior vena cava and an accompanying pulmonary artery thrombotic embolism was treated with hysterectomy and warfarin, which caused bleeding. While initially overlooked, a CTEPH diagnosis was reached.
{"title":"Case report for chronic thromboembolic pulmonary hypertension (CTEPH) caused by deep vein thrombosis due to uterine myoma","authors":"Hyun Jin Kim, H. Shin","doi":"10.15761/VDT.1000185","DOIUrl":"https://doi.org/10.15761/VDT.1000185","url":null,"abstract":"Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of pulmonary embolism. A deep vein thrombosis diagnosis due to uterine myoma compressing the inferior vena cava and an accompanying pulmonary artery thrombotic embolism was treated with hysterectomy and warfarin, which caused bleeding. While initially overlooked, a CTEPH diagnosis was reached.","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123018140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The PERTINI Method: A simple technique for re-sheathing a physician-modified endograft","authors":"F. De Santis","doi":"10.15761/vdt.1000193","DOIUrl":"https://doi.org/10.15761/vdt.1000193","url":null,"abstract":"","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"59 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121017119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Vassilopoulou, A. Tountopoulou, E. Korompoki, L. Poulou, Christos Gkogkas
Trigeminal neuralgia is a severe facial pain. Dural Arteriovenous Fistula is a very rare cause of this neuralgia. We present a 68 year old male with a severe left Trigeminal Neuralgia refractory to medical treatment without any abnormal finding in his initial brain MRI. One year later, α new brain MRI revealed a huge dural Arteriovenous Fistula (AVF) as the underlying cause of this painful prosopalgia. Successful transarterial dAVF embolization improved patient’s symptoms and subsequently his quality of life
{"title":"Trigeminal Neuralgia: The pain is a given, the cause is not","authors":"S. Vassilopoulou, A. Tountopoulou, E. Korompoki, L. Poulou, Christos Gkogkas","doi":"10.15761/VDT.1000175","DOIUrl":"https://doi.org/10.15761/VDT.1000175","url":null,"abstract":"Trigeminal neuralgia is a severe facial pain. Dural Arteriovenous Fistula is a very rare cause of this neuralgia. We present a 68 year old male with a severe left Trigeminal Neuralgia refractory to medical treatment without any abnormal finding in his initial brain MRI. One year later, α new brain MRI revealed a huge dural Arteriovenous Fistula (AVF) as the underlying cause of this painful prosopalgia. Successful transarterial dAVF embolization improved patient’s symptoms and subsequently his quality of life","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"179 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122498306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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