Pub Date : 2023-01-01Epub Date: 2023-09-29DOI: 10.5114/pg.2023.131595
Wojciech Marlicz, Anastasios Koulaouzidis, Dafni Charisopoulou, Janusz Jankowski, Maria Marlicz, Karolina Skonieczna-Zydecka, Patrycja Krynicka, Igor Loniewski, Jerzy Samochowiec, Grażyna Rydzewska, George Koulaouzidis
Burnout is common among physicians; it severely alters their health and has a negative impact on functioning of healthcare systems. Hypertension, increased cortisol levels, maladaptive behaviors with negative social consequences, and suboptimal quality of care have been associated with healthcare providers' burnout. As the number of patients with cancers, psychiatric and neurodegenerative disorders will rise, we need new solutions to maintain physicians' health and, therefore, quality of care. Coping strategies before the COVID-19 pandemic seem ineffective in scaling all the deficits of the global healthcare systems. Examples of new initiatives include new collaborative projects, such as COH-FIT (The Collaborative Outcomes study on Health and Functioning during Infection Times - https://www.coh-fit.com), which aims to collect global data and understand the impact of the COVID-19 pandemic on physical and mental health in order to identify various coping strategies for patients and healthcare workers during infection times, or MEMO (Minimizing Error, Maximizing Outcome), funded by the Agency of Healthcare Research and Quality (AHRQ). Others: i) Rome Foundation GastroPsych undertake efforts dedicated to the science and practice of psychogastroenterology, a burgeoning field with roots in behavioral intervention, cognitive science and experimental psychology focused on fostering the professional growth and collaboration of those engaged in medical practices, or ii) World Gastroenterology Organisation (WGO), Train The Trainers (TTT) program including a new topic of the impact of burnout on career longevity in order to foster strategies for staying healthy and increasing career satisfaction. There is a need for continuous development of digital technologies (e.g. training simulators, telemedicine, robots and artificial intelligence). Their implementation into medical practice is inevitable. Now more than ever, there is a need for a new spirit in healthcare. Together with others in the field, we believe this article is a desperate call for maximizing the use of novel technologies supported by collaborative interactions among healthcare providers and medical professionals of diverse medical fields.
{"title":"Burnout in healthcare - the Emperor's New Clothes.","authors":"Wojciech Marlicz, Anastasios Koulaouzidis, Dafni Charisopoulou, Janusz Jankowski, Maria Marlicz, Karolina Skonieczna-Zydecka, Patrycja Krynicka, Igor Loniewski, Jerzy Samochowiec, Grażyna Rydzewska, George Koulaouzidis","doi":"10.5114/pg.2023.131595","DOIUrl":"10.5114/pg.2023.131595","url":null,"abstract":"<p><p>Burnout is common among physicians; it severely alters their health and has a negative impact on functioning of healthcare systems. Hypertension, increased cortisol levels, maladaptive behaviors with negative social consequences, and suboptimal quality of care have been associated with healthcare providers' burnout. As the number of patients with cancers, psychiatric and neurodegenerative disorders will rise, we need new solutions to maintain physicians' health and, therefore, quality of care. Coping strategies before the COVID-19 pandemic seem ineffective in scaling all the deficits of the global healthcare systems. Examples of new initiatives include new collaborative projects, such as COH-FIT (The Collaborative Outcomes study on Health and Functioning during Infection Times - https://www.coh-fit.com), which aims to collect global data and understand the impact of the COVID-19 pandemic on physical and mental health in order to identify various coping strategies for patients and healthcare workers during infection times, or MEMO (Minimizing Error, Maximizing Outcome), funded by the Agency of Healthcare Research and Quality (AHRQ). Others: i) Rome Foundation GastroPsych undertake efforts dedicated to the science and practice of psychogastroenterology, a burgeoning field with roots in behavioral intervention, cognitive science and experimental psychology focused on fostering the professional growth and collaboration of those engaged in medical practices, or ii) World Gastroenterology Organisation (WGO), Train The Trainers (TTT) program including a new topic of the impact of burnout on career longevity in order to foster strategies for staying healthy and increasing career satisfaction. There is a need for continuous development of digital technologies (e.g. training simulators, telemedicine, robots and artificial intelligence). Their implementation into medical practice is inevitable. Now more than ever, there is a need for a new spirit in healthcare. Together with others in the field, we believe this article is a desperate call for maximizing the use of novel technologies supported by collaborative interactions among healthcare providers and medical professionals of diverse medical fields.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"18 3","pages":"274-280"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71485284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01Epub Date: 2023-09-22DOI: 10.5114/pg.2023.131395
Rani Ratheesh, Michael T Ulrich, Sherief Ghozy, Mohammed Al-Jaboori, Sandeep S Nayak
Introduction: Evidence regarding the association between diabetes mellitus (DM) and cholelithiasis is still inconsistent.
Aim: To examine the association between diabetes and gallstones and the commonly associated factors in a nationwide population-based cohort investigation.
Material and methods: The demographic and outcome variable data were extracted from the National Health and Nutrition Examination Survey (NHANES) database for the years 2017-2018.
Results: A total of 5376 individuals were included in the final analysis, with a mean age of 51.3 ±17.8 years. Females constituted 51.5% of the included individuals, and the overall mean body mass index (BMI) was 29.8 ±7.4 kg/m2. The prevalence of diabetes was 16.2% among the included individuals, with a mean age of 50.6 ±13.6 years at diagnosis of diabetes, and only 4.5% were taking insulin. The prevalence of cholelithiasis was 11.2%, with a mean age of 44.4 ±16.1 years at diagnosis, and 11.3% had previous cholecystectomy (gallbladder surgery.) There was a significant increase in gallstone rates among diabetic patients as compared to non-diabetics in the unadjusted (OR = 2.30; 95% CI: 1.89-2.79; p < 0.001) and adjusted (OR = 1.52; 95% CI: 1.20-1.92; p < 0.001) models. Moreover, this association was not time-dependent where the "age when first told you had diabetes" did not show a significant influence on the gallstone rate, whether in unadjusted (OR = 1.01; 95% CI: 1.00-1.02; p = 0.221) or adjusted (OR = 1.01; 95% CI: 0.99-1.03; p = 0.395) models. Furthermore, insulin usage was found to be a significant predictor of cholelithiasis, whether in unadjusted (OR = 2.39; 95% CI: 1.74-3.28; p < 0.001) or adjusted (OR = 1.52; 95% CI: 1.05-2.19; p = 0.026) models.
Conclusions: DM and insulin therapy are possible risk factors for developing cholelithiasis.
{"title":"The association between diabetes and gallstones: a nationwide population-based cohort study.","authors":"Rani Ratheesh, Michael T Ulrich, Sherief Ghozy, Mohammed Al-Jaboori, Sandeep S Nayak","doi":"10.5114/pg.2023.131395","DOIUrl":"10.5114/pg.2023.131395","url":null,"abstract":"<p><strong>Introduction: </strong>Evidence regarding the association between diabetes mellitus (DM) and cholelithiasis is still inconsistent.</p><p><strong>Aim: </strong>To examine the association between diabetes and gallstones and the commonly associated factors in a nationwide population-based cohort investigation.</p><p><strong>Material and methods: </strong>The demographic and outcome variable data were extracted from the National Health and Nutrition Examination Survey (NHANES) database for the years 2017-2018.</p><p><strong>Results: </strong>A total of 5376 individuals were included in the final analysis, with a mean age of 51.3 ±17.8 years. Females constituted 51.5% of the included individuals, and the overall mean body mass index (BMI) was 29.8 ±7.4 kg/m<sup>2</sup>. The prevalence of diabetes was 16.2% among the included individuals, with a mean age of 50.6 ±13.6 years at diagnosis of diabetes, and only 4.5% were taking insulin. The prevalence of cholelithiasis was 11.2%, with a mean age of 44.4 ±16.1 years at diagnosis, and 11.3% had previous cholecystectomy (gallbladder surgery.) There was a significant increase in gallstone rates among diabetic patients as compared to non-diabetics in the unadjusted (OR = 2.30; 95% CI: 1.89-2.79; <i>p</i> < 0.001) and adjusted (OR = 1.52; 95% CI: 1.20-1.92; <i>p</i> < 0.001) models. Moreover, this association was not time-dependent where the \"age when first told you had diabetes\" did not show a significant influence on the gallstone rate, whether in unadjusted (OR = 1.01; 95% CI: 1.00-1.02; <i>p</i> = 0.221) or adjusted (OR = 1.01; 95% CI: 0.99-1.03; <i>p</i> = 0.395) models. Furthermore, insulin usage was found to be a significant predictor of cholelithiasis, whether in unadjusted (OR = 2.39; 95% CI: 1.74-3.28; <i>p</i> < 0.001) or adjusted (OR = 1.52; 95% CI: 1.05-2.19; <i>p</i> = 0.026) models.</p><p><strong>Conclusions: </strong>DM and insulin therapy are possible risk factors for developing cholelithiasis.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"18 3","pages":"292-299"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71485292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01Epub Date: 2022-07-10DOI: 10.5114/pg.2022.118015
Grażyna Piotrowicz, Agata A Rudnik, Mariola Bidzan, Grażyna Rydzewska
Introduction: There are many studies on the influence of psychological factors in the appearance of symptoms and their treatment among gastroenterological patients. It is increasingly indicated that these factors are of great importance also for the quality of life of people struggling with a chronic disease.
Aim: To evaluate personality traits and emotional disorders in female patients with gastrointestinal conditions such as functional dyspepsia (FD), irritable bowel syndrome (IBS), or inflammatory bowel disease (IBD).
Material and methods: The sample of 28 patients was verified in terms of the disease using the GAST questionnaire and assessed by personality questionnaires and psychological tests: the Spielberger State-Trait Anxiety Inventory (STAI), EAS Temperament Survey, Eysenck Personality Inventory (EPQ-R), Coping Inventory for Stressful Situations (CISS); Beliefs about Pain Control Questionnaire (BPCQ), General Self-efficacy Scale (GSES), and Satisfaction with Life Scale (SWLS).
Results: The control group was recruited from female university students declaring full health. The conducted statistical analysis showed that there is a significant relationship between personality traits, psychological predispositions, and both the experience of illness and satisfaction with life among this specific group of patients.
Conclusions: This pilot study demonstrated the need for a personalized approach to gastroenterological patients, also based on their personality characteristics. Such an approach may increase the effectiveness of therapy and bring benefits in long-term treatment.
{"title":"Selected personality traits and emotional disorders of women diagnosed with gastrointestinal disease - a pilot study.","authors":"Grażyna Piotrowicz, Agata A Rudnik, Mariola Bidzan, Grażyna Rydzewska","doi":"10.5114/pg.2022.118015","DOIUrl":"10.5114/pg.2022.118015","url":null,"abstract":"<p><strong>Introduction: </strong>There are many studies on the influence of psychological factors in the appearance of symptoms and their treatment among gastroenterological patients. It is increasingly indicated that these factors are of great importance also for the quality of life of people struggling with a chronic disease.</p><p><strong>Aim: </strong>To evaluate personality traits and emotional disorders in female patients with gastrointestinal conditions such as functional dyspepsia (FD), irritable bowel syndrome (IBS), or inflammatory bowel disease (IBD).</p><p><strong>Material and methods: </strong>The sample of 28 patients was verified in terms of the disease using the GAST questionnaire and assessed by personality questionnaires and psychological tests: the Spielberger State-Trait Anxiety Inventory (STAI), EAS Temperament Survey, Eysenck Personality Inventory (EPQ-R), Coping Inventory for Stressful Situations (CISS); Beliefs about Pain Control Questionnaire (BPCQ), General Self-efficacy Scale (GSES), and Satisfaction with Life Scale (SWLS).</p><p><strong>Results: </strong>The control group was recruited from female university students declaring full health. The conducted statistical analysis showed that there is a significant relationship between personality traits, psychological predispositions, and both the experience of illness and satisfaction with life among this specific group of patients.</p><p><strong>Conclusions: </strong>This pilot study demonstrated the need for a personalized approach to gastroenterological patients, also based on their personality characteristics. Such an approach may increase the effectiveness of therapy and bring benefits in long-term treatment.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"1 1","pages":"300-307"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70474932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
[This corrects the article DOI: 10.5114/pg.2023.125882.].
[这更正了文章DOI: 10.5114/pg.2023.125882]。
{"title":"Erratum: Guidelines for the management of ulcerative colitis. Recommendations of the Polish Society of Gastroenterology and the Polish National Consultant in Gastroenterology. Erratum.","authors":"","doi":"10.5114/pg.2023.129421","DOIUrl":"https://doi.org/10.5114/pg.2023.129421","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.5114/pg.2023.125882.].</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"18 2","pages":"224"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b4/52/PG-18-51072.PMC10395064.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9939197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danuta Domżał-Magrowska, Marek K Kowalski, Ewa Małecka-Wojciesko
Introduction: The incidence of lactose intolerance in irritable bowel syndrome (IBS) varies in the literature (27-72%). Primary adult lactase deficiency (adult type hypolactasia) is the most common type of primary enzyme deficiency. Complaints related to lactose intolerance may overlap with the symptoms of IBS.
Aim: To assess the prevalence of primary hypolactasia in patients with IBS.
Material and methods: The study included 56 patients with IBS diagnosed based on the Rome III criteria and 23 healthy people. All study participants completed a questionnaire on IBS symptoms and lactose intolerance, and they underwent a hydrogen breath test (HBT) with lactose. In the group of patients with positive results of HBT, the polymorphism C/T -13910 and G/A -22018 in the promoter of the LCT gene encoding lactase was determined.
Results: Lactase deficiency was diagnosed in HBT in 34 (60.7%) patients with IBS and in the control group - in 10 (43.5%). Primary adult type hypolactasia was confirmed in 78.9% (n = 30; 79.3% in the study group; 77.8% in the control group). There were no statistically significant differences in the occurrence of LCT gene polymorphisms in particular IBS subtypes. Adult type hypolactasia was significantly more common in patients with severe than moderate and mild enzyme deficiency in HBT (p < 0.05).
Conclusions: The incidence of lactase deficiency in IBS patients is not different from that found in healthy subjects. Nevertheless, irrespective of the IBS subtype, lactose intolerance may pose additional issues in patients with IBS and requires the targeted treatment.
{"title":"The incidence of adult type hypolactasia in patients with irritable bowel syndrome.","authors":"Danuta Domżał-Magrowska, Marek K Kowalski, Ewa Małecka-Wojciesko","doi":"10.5114/pg.2023.126043","DOIUrl":"https://doi.org/10.5114/pg.2023.126043","url":null,"abstract":"<p><strong>Introduction: </strong>The incidence of lactose intolerance in irritable bowel syndrome (IBS) varies in the literature (27-72%). Primary adult lactase deficiency (adult type hypolactasia) is the most common type of primary enzyme deficiency. Complaints related to lactose intolerance may overlap with the symptoms of IBS.</p><p><strong>Aim: </strong>To assess the prevalence of primary hypolactasia in patients with IBS.</p><p><strong>Material and methods: </strong>The study included 56 patients with IBS diagnosed based on the Rome III criteria and 23 healthy people. All study participants completed a questionnaire on IBS symptoms and lactose intolerance, and they underwent a hydrogen breath test (HBT) with lactose. In the group of patients with positive results of HBT, the polymorphism C/T -13910 and G/A -22018 in the promoter of the LCT gene encoding lactase was determined.</p><p><strong>Results: </strong>Lactase deficiency was diagnosed in HBT in 34 (60.7%) patients with IBS and in the control group - in 10 (43.5%). Primary adult type hypolactasia was confirmed in 78.9% (<i>n</i> = 30; 79.3% in the study group; 77.8% in the control group). There were no statistically significant differences in the occurrence of LCT gene polymorphisms in particular IBS subtypes. Adult type hypolactasia was significantly more common in patients with severe than moderate and mild enzyme deficiency in HBT (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>The incidence of lactase deficiency in IBS patients is not different from that found in healthy subjects. Nevertheless, irrespective of the IBS subtype, lactose intolerance may pose additional issues in patients with IBS and requires the targeted treatment.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"18 1","pages":"110-114"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/68/95/PG-18-50388.PMC10050976.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9296105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01Epub Date: 2023-01-13DOI: 10.5114/pg.2023.124130
Serdar Şenol
The lymphatic system was first described by Asel-lius in 1627, and chylous leak (CL) was first reported by Morton in 1691 [1, 2]. It is defined as the leakage of milk-like, triglyceride-rich lymphatic fluid from the lymphatic system in to the peritoneal cavity [3]. It can cause fever, abdominal pain, abdominal distension, and abnormal white blood cell count and a delay in the withdrawal of the abdominal drainage tube. Even more serious, improper treatment will lead to celiac infection and abdominal bleeding, which results in prolonged hospitalization and increased costs. The incidence of CL after gastrectomy with D1–2 dissection is reported as 1.99%; however, D3–4 lymphadenectomy is associated with a higher incidence of CL of up to 6.3% [4], indicating that locally advanced diseases and extensive lymph node dissection lead to a higher incidence of CL
{"title":"Chylous leak following laparoscopic distal gastrectomy with D2 dissection for a locally advanced, distal obstructive gastric cancer.","authors":"Serdar Şenol","doi":"10.5114/pg.2023.124130","DOIUrl":"10.5114/pg.2023.124130","url":null,"abstract":"The lymphatic system was first described by Asel-lius in 1627, and chylous leak (CL) was first reported by Morton in 1691 [1, 2]. It is defined as the leakage of milk-like, triglyceride-rich lymphatic fluid from the lymphatic system in to the peritoneal cavity [3]. It can cause fever, abdominal pain, abdominal distension, and abnormal white blood cell count and a delay in the withdrawal of the abdominal drainage tube. Even more serious, improper treatment will lead to celiac infection and abdominal bleeding, which results in prolonged hospitalization and increased costs. The incidence of CL after gastrectomy with D1–2 dissection is reported as 1.99%; however, D3–4 lymphadenectomy is associated with a higher incidence of CL of up to 6.3% [4], indicating that locally advanced diseases and extensive lymph node dissection lead to a higher incidence of CL","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"1 1","pages":"344-346"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70474641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colorectal cancer is one of the most prevalent types of cancer, with histopathologic examination of biopsied tissue samples remaining the gold standard for diagnosis. During the past years, artificial intelligence (AI) has steadily found its way into the field of medicine and pathology, especially with the introduction of whole slide imaging (WSI). The main outcome of interest was the composite balanced accuracy (ACC) as well as the F1 score. The average reported ACC from the collected studies was 95.8 ±3.8%. Reported F1 scores reached as high as 0.975, with an average of 89.7 ±9.8%, indicating that existing deep learning algorithms can achieve in silico distinction between malignant and benign. Overall, the available state-of-the-art algorithms are non-inferior to pathologists for image analysis and classification tasks. However, due to their inherent uniqueness in their training and lack of widely accepted external validation datasets, their generalization potential is still limited.
结直肠癌是发病率最高的癌症类型之一,活组织样本的组织病理学检查仍然是诊断的金标准。在过去几年中,人工智能(AI)逐渐进入医学和病理学领域,特别是随着全切片成像(WSI)技术的引入。我们关注的主要结果是综合平衡准确度(ACC)和 F1 分数。所收集研究报告的平均 ACC 为 95.8 ±3.8%。报告的 F1 分数高达 0.975,平均值为 89.7 ±9.8%,这表明现有的深度学习算法可以实现恶性和良性的硅学区分。总体而言,现有的先进算法在图像分析和分类任务方面并不逊色于病理学家。然而,由于其训练的固有独特性以及缺乏被广泛接受的外部验证数据集,其通用化潜力仍然有限。
{"title":"Tissue classification and diagnosis of colorectal cancer histopathology images using deep learning algorithms. Is the time ripe for clinical practice implementation?","authors":"David Dimitris Chlorogiannis, Georgios-Ioannis Verras, Vasiliki Tzelepi, Anargyros Chlorogiannis, Anastasios Apostolos, Konstantinos Kotis, Christos-Nikolaos Anagnostopoulos, Andreas Antzoulas, Spyridon Davakis, Michail Vailas, Dimitrios Schizas, Francesk Mulita","doi":"10.5114/pg.2023.130337","DOIUrl":"10.5114/pg.2023.130337","url":null,"abstract":"<p><p>Colorectal cancer is one of the most prevalent types of cancer, with histopathologic examination of biopsied tissue samples remaining the gold standard for diagnosis. During the past years, artificial intelligence (AI) has steadily found its way into the field of medicine and pathology, especially with the introduction of whole slide imaging (WSI). The main outcome of interest was the composite balanced accuracy (ACC) as well as the F1 score. The average reported ACC from the collected studies was 95.8 ±3.8%. Reported F1 scores reached as high as 0.975, with an average of 89.7 ±9.8%, indicating that existing deep learning algorithms can achieve <i>in silico</i> distinction between malignant and benign. Overall, the available state-of-the-art algorithms are non-inferior to pathologists for image analysis and classification tasks. However, due to their inherent uniqueness in their training and lack of widely accepted external validation datasets, their generalization potential is still limited.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"1 1","pages":"353-367"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10985751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01Epub Date: 2023-07-20DOI: 10.5114/pg.2023.129946
Katarina Jankovic, Zoran Krivokapic, Ivan Jovanovic
{"title":"Jejunal gastrointestinal stromal tumour: a rare cause of severe small bowel bleeding.","authors":"Katarina Jankovic, Zoran Krivokapic, Ivan Jovanovic","doi":"10.5114/pg.2023.129946","DOIUrl":"10.5114/pg.2023.129946","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"1 1","pages":"451-453"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10985746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01Epub Date: 2023-09-22DOI: 10.5114/pg.2023.131398
Anett Dávid, Kata Judit Szántó, Anna Fábián, Tamás Resál, Klaudia Farkas, Emese Hallgató, Pál Miheller, Patrícia Sarlós, Tamás Molnár, Beatrix Rafael
Introduction: Inflammatory bowel diseases (Crohn's disease (CD) and ulcerative colitis (UC)) are chronic, immune-mediated diseases with unclear aetiology, characterized by relapsing inflammation of the gastrointestinal tract. These conditions significantly impair patients' physical and mental condition and quality of life.
Aim: To investigate the impact of the current pandemic situation on inflammatory bowel disease (IBD) patients' psychological status and to determine factors that mediate the level of depression, anxiety, and health-related quality of life.
Material and methods: This was a multicentre, observational, cross-sectional, questionnaire-based study. A total of 206 participants (male: 34%) were involved. The online survey consisted of 8 different psychological measures (such as depression, anxiety, coronavirus distress, health-related quality of life, etc.) and other therapy-specific and sociodemographic factors.
Results: 28.2% of respondents showed depressive symptoms and 11.2% indicated moderate to severe anxiety. Also, 27.7% revealed mild, moderate, or severe distress regarding the coronavirus situation. According to regression analysis, anxiety and coronavirus distress are mostly influenced by psychological factors. In contrast, the changes in quality of life and depression can be explained by disease-specific and psychological factors as well.
Conclusions: Patients need more attention during this period to help them cope with psychological factors and prevent their IBD from becoming worse.
{"title":"Psychological characteristics of patients with inflammatory bowel disease during the first wave of COVID-19.","authors":"Anett Dávid, Kata Judit Szántó, Anna Fábián, Tamás Resál, Klaudia Farkas, Emese Hallgató, Pál Miheller, Patrícia Sarlós, Tamás Molnár, Beatrix Rafael","doi":"10.5114/pg.2023.131398","DOIUrl":"10.5114/pg.2023.131398","url":null,"abstract":"<p><strong>Introduction: </strong>Inflammatory bowel diseases (Crohn's disease (CD) and ulcerative colitis (UC)) are chronic, immune-mediated diseases with unclear aetiology, characterized by relapsing inflammation of the gastrointestinal tract. These conditions significantly impair patients' physical and mental condition and quality of life.</p><p><strong>Aim: </strong>To investigate the impact of the current pandemic situation on inflammatory bowel disease (IBD) patients' psychological status and to determine factors that mediate the level of depression, anxiety, and health-related quality of life.</p><p><strong>Material and methods: </strong>This was a multicentre, observational, cross-sectional, questionnaire-based study. A total of 206 participants (male: 34%) were involved. The online survey consisted of 8 different psychological measures (such as depression, anxiety, coronavirus distress, health-related quality of life, etc.) and other therapy-specific and sociodemographic factors.</p><p><strong>Results: </strong>28.2% of respondents showed depressive symptoms and 11.2% indicated moderate to severe anxiety. Also, 27.7% revealed mild, moderate, or severe distress regarding the coronavirus situation. According to regression analysis, anxiety and coronavirus distress are mostly influenced by psychological factors. In contrast, the changes in quality of life and depression can be explained by disease-specific and psychological factors as well.</p><p><strong>Conclusions: </strong>Patients need more attention during this period to help them cope with psychological factors and prevent their IBD from becoming worse.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"18 3","pages":"334-343"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71485290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Kotkowicz-Szczur, Edyta Szymańska, Rafał Kisielewski, Jarosław Kierkuś
Problems with intimacy and sexuality are one of the major concerns of patients with inflammatory bowel diseases (IBD). Many symptoms, complications, and consequences of these disorders are likely to impact on body image, intimacy, and sexual function. Moreover, mood disorders, in particular depression, which is a major risk factor for sexual dysfunctions, are reported to be common in chronic illnesses such as IBD. However, despite this obvious relevance, sexual problems are rarely addressed in the clinical management of patients with IBD. The aim of this review was to discuss sexual problem in people with IBD.
{"title":"Sexual functions in individuals with inflammatory bowel diseases.","authors":"Marta Kotkowicz-Szczur, Edyta Szymańska, Rafał Kisielewski, Jarosław Kierkuś","doi":"10.5114/pg.2023.126042","DOIUrl":"https://doi.org/10.5114/pg.2023.126042","url":null,"abstract":"<p><p>Problems with intimacy and sexuality are one of the major concerns of patients with inflammatory bowel diseases (IBD). Many symptoms, complications, and consequences of these disorders are likely to impact on body image, intimacy, and sexual function. Moreover, mood disorders, in particular depression, which is a major risk factor for sexual dysfunctions, are reported to be common in chronic illnesses such as IBD. However, despite this obvious relevance, sexual problems are rarely addressed in the clinical management of patients with IBD. The aim of this review was to discuss sexual problem in people with IBD.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"18 1","pages":"56-60"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e9/25/PG-18-50387.PMC10050983.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9296107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}