Pub Date : 2009-01-01DOI: 10.1016/S0079-6468(08)00205-1
Michael J Palmer
{"title":"Endothelin receptor antagonists: status and learning 20 years on.","authors":"Michael J Palmer","doi":"10.1016/S0079-6468(08)00205-1","DOIUrl":"https://doi.org/10.1016/S0079-6468(08)00205-1","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"47 ","pages":"203-37"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(08)00205-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28079108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-01-01DOI: 10.1016/S0079-6468(08)00206-3
Barry C Jones, Donald S Middleton, Kuresh Youdim
{"title":"Cytochrome P450 metabolism and inhibition: analysis for drug discovery.","authors":"Barry C Jones, Donald S Middleton, Kuresh Youdim","doi":"10.1016/S0079-6468(08)00206-3","DOIUrl":"https://doi.org/10.1016/S0079-6468(08)00206-3","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"47 ","pages":"239-63"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(08)00206-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28079109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-01-01DOI: 10.1016/S0079-6468(07)00003-3
Andrew P Lightfoot, James N C Kew, John Skidmore
{"title":"Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators.","authors":"Andrew P Lightfoot, James N C Kew, John Skidmore","doi":"10.1016/S0079-6468(07)00003-3","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00003-3","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"46 ","pages":"131-71"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00003-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-01-01DOI: 10.1016/S0079-6468(07)00002-1
Xiangdong Su, Nigel Vicker, Barry V L Potter
{"title":"Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.","authors":"Xiangdong Su, Nigel Vicker, Barry V L Potter","doi":"10.1016/S0079-6468(07)00002-1","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00002-1","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"46 ","pages":"29-130"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00002-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-01-01DOI: 10.1016/S0079-6468(07)00008-2
G Lawton, D R Witty
{"title":"Appropriate selection of biochemical targets is one of the most important driver of cost-effectiveness in the discovery of new medicines. Preface.","authors":"G Lawton, D R Witty","doi":"10.1016/S0079-6468(07)00008-2","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00008-2","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"46 ","pages":"v-vi"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00008-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-01-01DOI: 10.1016/S0079-6468(07)00001-X
Michael Rowley
{"title":"The discovery of raltegravir, an integrase inhibitor for the treatment of HIV infection.","authors":"Michael Rowley","doi":"10.1016/S0079-6468(07)00001-X","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00001-X","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"46 ","pages":"1-28"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00001-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-01-01DOI: 10.1016/S0079-6468(07)00005-7
Matthias Körner, Ulrich Tibes
{"title":"Histone deacetylase inhibitors: a novel class of anti-cancer agents on its way to the market.","authors":"Matthias Körner, Ulrich Tibes","doi":"10.1016/S0079-6468(07)00005-7","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00005-7","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"46 ","pages":"205-80"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00005-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-01-01DOI: 10.1016/S0079-6468(07)00006-9
Nathaniel J T Monck, Guy A Kennett
{"title":"5-HT2C ligands: recent progress.","authors":"Nathaniel J T Monck, Guy A Kennett","doi":"10.1016/S0079-6468(07)00006-9","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00006-9","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"46 ","pages":"281-390"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00006-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-01-01DOI: 10.1016/S0079-6468(06)45501-6
Robert A Goodnow, Paul Gillespie
{"title":"Hit and Lead identification: efficient practices for drug discovery.","authors":"Robert A Goodnow, Paul Gillespie","doi":"10.1016/S0079-6468(06)45501-6","DOIUrl":"https://doi.org/10.1016/S0079-6468(06)45501-6","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"45 ","pages":"1-61"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(06)45501-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26536790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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