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Progress in medicinal chemistry最新文献

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Property-based design in the optimisation of benzamide glucokinase activators: from hit to clinic. 苯甲酰胺葡萄糖激酶活化剂优化中的基于性能的设计:从hit到临床。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2013-01-01 DOI: 10.1016/B978-0-444-62652-3.00001-6
Darren McKerrecher, Michael J Waring
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引用次数: 4
Hematopoietic prostaglandin D synthase inhibitors. 造血前列腺素D合成酶抑制剂。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2012-01-01 DOI: 10.1016/B978-0-12-396493-9.00004-2
Sukanthini Thurairatnam
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引用次数: 20
TRPV1 antagonists: clinical setbacks and prospects for future development. TRPV1拮抗剂:临床挫折及未来发展前景
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2012-01-01 DOI: 10.1016/B978-0-12-396493-9.00002-9
Michael E Kort, Philip R Kym
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引用次数: 57
Multivalent dual pharmacology muscarinic antagonist and β₂ agonist (MABA) molecules for the treatment of COPD. 多价双重药理毒蕈碱拮抗剂和β 2激动剂(MABA)分子治疗COPD。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2012-01-01 DOI: 10.1016/B978-0-12-396493-9.00003-0
Adam D Hughes, Alexander McNamara, Tod Steinfeld
{"title":"Multivalent dual pharmacology muscarinic antagonist and β₂ agonist (MABA) molecules for the treatment of COPD.","authors":"Adam D Hughes, Alexander McNamara, Tod Steinfeld","doi":"10.1016/B978-0-12-396493-9.00003-0","DOIUrl":"https://doi.org/10.1016/B978-0-12-396493-9.00003-0","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"51 ","pages":"71-95"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-396493-9.00003-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40171224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Small molecule bromodomain inhibitors: extending the druggable genome. 小分子溴结构域抑制剂:扩展可药物基因组。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2012-01-01 DOI: 10.1016/B978-0-12-396493-9.00001-7
Chun-Wa Chung
{"title":"Small molecule bromodomain inhibitors: extending the druggable genome.","authors":"Chun-Wa Chung","doi":"10.1016/B978-0-12-396493-9.00001-7","DOIUrl":"https://doi.org/10.1016/B978-0-12-396493-9.00001-7","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"51 ","pages":"1-55"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-396493-9.00001-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40171222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 43
The large scale restructuring of pharmaceutical company research function. Preface. 医药企业研究职能的大规模重组。前言。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2012-01-01 DOI: 10.1016/B978-0-12-396493-9.00005-4
G Lawton, David R Witty
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引用次数: 0
Designing drugs to avoid toxicity. 设计药物以避免毒性。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/B978-0-12-381290-2.00001-X
Graham F Smith
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引用次数: 85
Prostaglandin D₂ receptor CRTH2 antagonists for the treatment of inflammatory diseases. 前列腺素D 2受体CRTH2拮抗剂治疗炎性疾病。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/B978-0-12-381290-2.00002-1
Jian Jeffrey Chen, Alison L Budelsky
{"title":"Prostaglandin D₂ receptor CRTH2 antagonists for the treatment of inflammatory diseases.","authors":"Jian Jeffrey Chen, Alison L Budelsky","doi":"10.1016/B978-0-12-381290-2.00002-1","DOIUrl":"https://doi.org/10.1016/B978-0-12-381290-2.00002-1","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"50 ","pages":"49-107"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-381290-2.00002-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29667944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Drug discovery projects. Preface. 药物发现项目。前言。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/b978-0-12-381290-2.00012-4
G Lawton, David R Witty
{"title":"Drug discovery projects. Preface.","authors":"G Lawton, David R Witty","doi":"10.1016/b978-0-12-381290-2.00012-4","DOIUrl":"https://doi.org/10.1016/b978-0-12-381290-2.00012-4","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":"50 ","pages":"v-vi"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29801305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic applications of iminosugars: current perspectives and future opportunities. 亚糖的治疗应用:目前的观点和未来的机会。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/B978-0-12-381290-2.00004-5
Graeme Horne, Francis X Wilson
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引用次数: 67
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