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Progress in medicinal chemistry最新文献

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Multivalent dual pharmacology muscarinic antagonist and β₂ agonist (MABA) molecules for the treatment of COPD. 多价双重药理毒蕈碱拮抗剂和β 2激动剂(MABA)分子治疗COPD。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2012-01-01 DOI: 10.1016/B978-0-12-396493-9.00003-0
Adam D Hughes, Alexander McNamara, Tod Steinfeld
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引用次数: 25
Small molecule bromodomain inhibitors: extending the druggable genome. 小分子溴结构域抑制剂:扩展可药物基因组。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2012-01-01 DOI: 10.1016/B978-0-12-396493-9.00001-7
Chun-Wa Chung
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引用次数: 43
The large scale restructuring of pharmaceutical company research function. Preface. 医药企业研究职能的大规模重组。前言。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2012-01-01 DOI: 10.1016/B978-0-12-396493-9.00005-4
G Lawton, David R Witty
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引用次数: 0
Designing drugs to avoid toxicity. 设计药物以避免毒性。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/B978-0-12-381290-2.00001-X
Graham F Smith
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引用次数: 85
Prostaglandin D₂ receptor CRTH2 antagonists for the treatment of inflammatory diseases. 前列腺素D 2受体CRTH2拮抗剂治疗炎性疾病。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/B978-0-12-381290-2.00002-1
Jian Jeffrey Chen, Alison L Budelsky
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引用次数: 20
Drug discovery projects. Preface. 药物发现项目。前言。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/b978-0-12-381290-2.00012-4
G Lawton, David R Witty
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引用次数: 0
Therapeutic applications of iminosugars: current perspectives and future opportunities. 亚糖的治疗应用:目前的观点和未来的机会。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/B978-0-12-381290-2.00004-5
Graeme Horne, Francis X Wilson
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引用次数: 67
Progress in the development of small molecule therapeutics targeting Th17 cell function for the treatment of immune-inflammatory diseases. 靶向Th17细胞功能治疗免疫炎性疾病的小分子药物研究进展
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2011-01-01 DOI: 10.1016/B978-0-12-381290-2.00003-3
Stephen Shuttleworth, Paul Townsend, Franck Silva, Alexander Cecil, Thomas Hill, Cyrille Tomassi, Helen Rogers, Rebecca Harrison
{"title":"Progress in the development of small molecule therapeutics targeting Th17 cell function for the treatment of immune-inflammatory diseases.","authors":"Stephen Shuttleworth, Paul Townsend, Franck Silva, Alexander Cecil, Thomas Hill, Cyrille Tomassi, Helen Rogers, Rebecca Harrison","doi":"10.1016/B978-0-12-381290-2.00003-3","DOIUrl":"https://doi.org/10.1016/B978-0-12-381290-2.00003-3","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-381290-2.00003-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29667945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
The Journey to the Discovery of Boceprevir: an NS3-NS4 HCV protease inhibitor for the treatment of chronic hepatitis C. Boceprevir的发现之旅:用于治疗慢性丙型肝炎的NS3-NS4 HCV蛋白酶抑制剂。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2010-01-01 DOI: 10.1016/S0079-6468(10)49001-3
Kevin X Chen, F George Njoroge
{"title":"The Journey to the Discovery of Boceprevir: an NS3-NS4 HCV protease inhibitor for the treatment of chronic hepatitis C.","authors":"Kevin X Chen, F George Njoroge","doi":"10.1016/S0079-6468(10)49001-3","DOIUrl":"https://doi.org/10.1016/S0079-6468(10)49001-3","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(10)49001-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40082382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
A decade of progress in the discovery and development of 'atypical' antipsychotics. 发现和开发“非典型”抗精神病药物的十年进展。
Q1 Pharmacology, Toxicology and Pharmaceutics
Progress in medicinal chemistry
Pub Date : 2010-01-01 DOI: 10.1016/S0079-6468(10)49002-5
Gregor J MacDonald, José Manuel Bartolomé
{"title":"A decade of progress in the discovery and development of 'atypical' antipsychotics.","authors":"Gregor J MacDonald, José Manuel Bartolomé","doi":"10.1016/S0079-6468(10)49002-5","DOIUrl":"https://doi.org/10.1016/S0079-6468(10)49002-5","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(10)49002-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40082383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
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