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Radiation adaptive response: the biophysical phenomenon and its theoretical description. 辐射适应反应:生物物理现象及其理论描述。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae053
Krzysztof W Fornalski, Łukasz Adamowski, Ernest Bugała, Rafał Jarmakiewicz, Julianna Krasowska, Łukasz Piotrowski

The radiation adaptive response (or radioadaptation) effect is a biophysical and radiobiological phenomenon responsible for, e.g. the enhancement of repair processes, cell cycle and apoptosis regulation or enhancement of antioxidant production in cells/organisms irradiated by low doses and low dose-rates of ionising radiation. This phenomenon, however, is not always present, which creates many problems both for experimenters and theoreticians. Here we propose a comprehensive and complete theoretical model of radioadaptation grounded in mathematical concept of dose- and time-related probability function of the adaptive response appearance. This can be used in the context of two special cases of the adaptive response: the Raper-Yonezawa (priming dose) effect or constant low-dose-rate irradiation (e.g. for high natural background). This complete theoretical approach is supported by Monte Carlo simulations and real-experimental data used for model calibration and validation.

辐射适应性反应(或辐射适应)效应是一种生物物理和辐射生物学现象,例如,在受到低剂量和低剂量率电离辐射照射的细胞/机体中,辐射适应性反应可增强修复过程、调节细胞周期和凋亡,或增强抗氧化剂的产生。然而,这种现象并不总是存在,这就给实验者和理论家带来了许多问题。在此,我们提出了一个全面、完整的辐射适应理论模型,该模型以适应反应外观的剂量和时间相关概率函数的数学概念为基础。该模型可用于适应性反应的两种特殊情况:Raper-Yonezawa(启动剂量)效应或恒定低剂量率辐照(如高天然本底)。这一完整的理论方法得到了蒙特卡罗模拟和用于模型校准和验证的实际实验数据的支持。
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引用次数: 0
Should the current radiation protection paradigm and its recommendations be modified to make them more fit to protect the public in future nuclear emergencies? 当前的辐射防护范例及其建议是否应加以修改,使其更适合在未来的核紧急情况下保护公众?
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae088
James Mc Laughlin

The present radiation protection paradigm and its associated recommendations as developed by bodies such as the ICRP have performed very well over past decades both for those occupationally exposed to radiation and for the public in planned exposures. There is, however, growing evidence that the role played by this paradigm in the decision-making process to protect the public in nuclear emergencies in the past may have, unwittingly and unintentionally, caused more harm than good to some sections of the public. This seems to have been the case in the use of population evacuation as the principal protection response to the Chernobyl (1986) and Fukushima (2011) accidents. There is thus a need to develop improved guidelines or tools on how to apply radiation protection recommendations for the public compatible with the Principle of Justification in the event of any future major radiation emergencies. It can also be argued that the present radiation protection paradigm, with its emphasis primarily on the physical health detriments from radiation, should be more inclusive and needs to shift to a more holistic or total health approach than heretofore to include mental health effects associated with nuclear emergencies. For severe mental health effects, some of the consequences, such as suicide, can even be as or more severe than most physical detriments likely to be suffered by those affected.

由国际辐射防护委员会等机构制定的现行辐射防护范例及其相关建议,在过去的几十年中,无论是对职业辐照者,还是对计划辐照的公众,都发挥了很好的作用。然而,越来越多的证据表明,在过去的核紧急情况中,这一范例在保护公众的决策过程中所发挥的作用,可能在不知不觉中无意地对某些公众造成了弊大于利的影响。切尔诺贝利核事故(1986 年)和福岛核事故(2011 年)中将人口疏散作为主要保护措施的做法似乎就是这种情况。因此,有必要制定更好的准则或工具,说明在未来发生任何重大辐射紧急情况时,如何根据 "合理原则 "为公众提供辐射防护建议。也可以说,目前的辐射防护模式主要强调辐射对身体健康的危害,应该更具包容性,需要转向比以往更全面或整体健康的方法,以包括与核紧急情况相关的心理健康影响。就严重的心理健康影响而言,自杀等一些后果甚至可能与受影响者可能遭受的大多数身体损害一样严重,甚至更为严重。
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引用次数: 0
Carbon accumulation model for simulating 14C radioactivity in Chinese yam grown from a seed bulbil. 模拟鳞茎种子生长的中国山药中 14C 放射性的碳积累模型。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae026
Takashi Tani, Ryuji Arai

Modeling carbon accumulation in crop plants is key to evaluating the transfer of atmospheric 14C into the edible parts of the plants growing near nuclear facilities. Chinese yam 'Nagaimo' (Dioscorea polystachya Turcz.) is a major crop cultivated near a spent nuclear fuel reprocessing plant in Rokkasho, Aomori, Japan. We developed a dynamic compartment model for assessing carbon and 14C accumulation in Chinese yam grown from a seed bulbil in the field. Light and temperature dependence of leaf photosynthesis and temperature dependence of respiration in leaves, stems and belowground parts (tuber and root) were incorporated into the model. Estimated amounts of carbon in the leaves, stems and belowground parts were good agreement with the measured data from the field. Simulation results of 14C accumulation using this model indicated that the accumulation of 14C in belowground parts at the harvest depends on the rate of photosynthesis on the day of exposure.

建立作物植物的碳积累模型是评估大气中的 14C 是否转移到核设施附近植物可食用部分的关键。中国山药'Nagaimo'(Dioscorea polystachya Turcz.)是在日本青森县六所的乏核燃料后处理厂附近种植的一种主要作物。我们建立了一个动态分区模型,用于评估在田间从球茎种子开始生长的中国山药的碳和 14C 积累情况。模型中包括叶片光合作用的光和温度依赖性,以及叶片、茎和地下部分(块茎和根)呼吸作用的温度依赖性。叶片、茎和地下部分的碳估计量与田间测量数据十分吻合。利用该模型模拟 14C 积累的结果表明,收获时地下部分的 14C 积累取决于暴露当天的光合作用速率。
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引用次数: 0
Development of evaluation method for radiocesium availability in soil by biomimetic approach. 利用仿生学方法开发土壤中铯可用性的评估方法。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae129
Akira Takeda, Yusuke Unno, Mathew J B Swallow, Yasumi Yagasaki, Tetsuo Yasutaka, Naofumi Akata

Applicability of biomimetic approach with simulation of plant uptake for assessment of radiocesium availability in soil was investigated. The soil spiked with 137Cs tracer was contacted with wicking material and copper-substituted prussian blue (Cu-PB), which simulate transpirationally induced mass flow and concentration gradient-induced diffusion of radiocesiumin the soil, respectively. Comparison of the removed 137Cs to the wick and the wick + Cu-PB from the soil during the contact period of 12 weeks suggested that the diffusion process has larger contribution than the mass flow process in radiocesium dynamics in root zone. The change of the removed rate of 137Cs from the soil was reflected that its availability decreased with the time elapsing and with subjecting repeated wet-dry treatment. The results suggest that the biomimetic approach can be applicable to the realistic evaluation of the availability of radiocesium in soil.

研究了模拟植物吸收的生物模拟方法在评估土壤中铯的可用性方面的适用性。添加了 137Cs 示踪剂的土壤与吸芯材料和铜代普鲁士蓝(Cu-PB)接触,这两种材料分别模拟了土壤中镭铯的蒸腾诱导质量流和浓度梯度诱导扩散。在 12 周的接触期内,比较从土壤中清除到灯芯和灯芯 + Cu-PB 中的 137Cs 表明,在根区镭铯动力学中,扩散过程比质量流过程的贡献更大。土壤中 137Cs 去除率的变化反映了其可用性随着时间的推移和反复干湿处理而降低。结果表明,生物模拟方法可用于对土壤中铯的可用性进行实际评估。
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引用次数: 0
Investigation of short-term chemical changes in stable ruthenium added to soil by using X-ray absorption fine-structure analysis. 利用 X 射线吸收精细结构分析法研究添加到土壤中的稳定钌的短期化学变化。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae083
Yusuke Unno, Akira Takeda

Radioactive ruthenium may be accidentally released from spent nuclear fuel reprocessing plants to the surrounding environment. However, research on the chemical behavior of radioactive Ru in the environment is limited, and the complex chemical properties of this element complicate the application of extraction methods for the analyses of its chemical forms. To obtain basic information regarding the outcome of radioactive Ru in the environment, we investigated the changes in the form of stable Ru added to soil through X-ray absorption fine-structure (XAFS) analysis. This study uses ruthenium tetroxide (RuO4), ruthenium dioxide (RuO2), ruthenium nitrosyl nitrate (Ru(NO)(NO3)3) and ruthenium chloride (RuCl3) as test sources. These are added to ultrapure water, soil solution or fresh soil samples, which are analyzed using XAFS immediately or 5 days after Ru addition. The Ru K-edge X-ray absorption near edge structure spectra acquired immediately after Ru addition differed with respect to the source. The XAFS results suggest that RuO4 immediately changes to tetravalent form after deposition from air to soil. For RuCl3, the ionic structure in the vicinity of Ru is affected by the soil even if the valence does not change immediately. By contrast, RuO2 and Ru(NO)(NO3)3 are highly stable in soil. The results show that the chemical forms of RuO2 and Ru(NO)(NO3)3 added to the soil solution and soil are retained for 5 days, whereas those of RuCl3 and RuO4 are affected by the soil solution and soil within a short period. These results emphasize the need to focus on the chemical form of Ru deposits and the form change after Ru addition when investigating the environmental fate of radioactive Ru.

放射性钌可能会从乏核燃料后处理厂意外释放到周围环境中。然而,有关放射性钌在环境中的化学行为的研究十分有限,而且这种元素的化学性质复杂,使得应用萃取方法分析其化学形态变得复杂。为了获得有关环境中放射性 Ru 结果的基本信息,我们通过 X 射线吸收精细结构(XAFS)分析,研究了添加到土壤中的稳定 Ru 的形态变化。这项研究使用四氧化三钌(RuO4)、二氧化钌(RuO2)、亚硝酸钌(Ru(NO)(NO3)3)和氯化钌(RuCl3)作为测试源。将这些物质添加到超纯水、土壤溶液或新鲜土壤样本中,在添加 Ru 后立即或 5 天后使用 XAFS 对样本进行分析。添加 Ru 后立即获得的 Ru K 边 X 射线吸收近缘结构光谱因源而异。XAFS 结果表明,RuO4 从空气中沉积到土壤中后立即转变为四价形式。对于 RuCl3,即使价态没有立即发生变化,Ru 附近的离子结构也会受到土壤的影响。相比之下,RuO2 和 Ru(NO)(NO3)3 在土壤中非常稳定。结果表明,加入土壤溶液和土壤中的 RuO2 和 Ru(NO)(NO3)3 的化学形态可保持 5 天,而 RuCl3 和 RuO4 的化学形态则会在短时间内受到土壤溶液和土壤的影响。这些结果表明,在研究放射性 Ru 的环境归宿时,需要关注 Ru 沉积物的化学形态以及加入 Ru 后的形态变化。
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引用次数: 0
Atmospheric concentrations of 7Be and 210Pb in weekly aerosols at Hirosaki, a heavy snowfall area in Japan. 日本大雪地区弘前每周气溶胶中 7Be 和 210Pb 的大气浓度。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae156
Khemruthai Kheamsiri, Oumar Bobbo Modibo, Bagus Sidik Waskito Hadi, Haruka Kuwata, Ryohei Yamada, Chutima Kranrod, Naofumi Akata

To understand the regional properties of atmospheric 7Be and 210Pb concentrations at Hirosaki, aerosol samples were collected weekly for the investigation. Total suspended particles (TSP) concentration ranged from 0.14 to 1.19 mg m-3 with a mean value of 0.29 ± 0.08 mg m-3. The activity concentrations during the observation period have shown a similar trend between 7Be and 210Pb, comparable to reported studies. The activity concentrations of 7Be and 210Pb ranged from 0.46 to 4.94 mBq m-3 with an average of 2.22 mBq m-3 and from 0.26 to 1.29 mBq m-3 with an average of 0.64 mBq m-3, respectively. The relation between precipitation and radionuclide concentrations indicated that precipitation is an essential factor in the radionuclide removal process. The rainfall/snowfall had a significant impact on the deposition, and the process was greatly affected by the changes in the features of raindrops and snowflakes, such as intensity, shape, surface area, and falling speed.

为了了解弘前大气中 7Be 和 210Pb 浓度的区域特性,调查人员每周收集气溶胶样本。总悬浮颗粒物(TSP)浓度范围为 0.14 至 1.19 毫克/立方米,平均值为 0.29 ± 0.08 毫克/立方米。在观测期间,7Be 和 210Pb 的放射性浓度呈现出类似的趋势,与已报道的研究结果相当。7Be 和 210Pb 的放射性活度濃度分別介乎 0.46 至 4.94 mBq m-3,平均值為 2.22 mBq m-3,以及 0.26 至 1.29 mBq m-3,平均值為 0.64 mBq m-3。降水与放射性核素浓度之间的关系表明,降水是放射性核素清除过程中的一个重要因素。降雨/降雪对沉积有重要影响,雨滴和雪花的强度、形状、表面积和下落速度等特征的变化对沉积过程有很大影响。
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引用次数: 0
Absorption and translocation to fruit for cesium applied on apple tree leaf surface. 苹果树叶面对铯的吸收和向果实的转移。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae069
Hitoshi Kawabata, Masumi Yanai, Yuichi Takaku, Shun'ichi Hisamatsu

We investigated the behavior of stable Cs+ ions contained in droplets applied directly on the leaf surfaces of plumleaf crab apple trees (2-3 years old Malus domestica 'Alps Otome') at three different fruit growing stages: before bearing fruit, early fruit development and late fruit development stages. Most of the Cs was rapidly transferred from the leaf surfaces into the applied leaves after application, and then gradually transferred to the fruit through the branches. The mean proportion of Cs transferred to fruit by harvest time ranged from 11 to 30% not directly depending on the fruit growing stages. Cs absorption from leaf surfaces was faster at early and late fruit development stages than before bearing fruit stage, and Cs transfer from leaf surfaces to the fruit was faster as the fruit growing stage progressed. To describe the transfer of Cs, we constructed a compartment model using the datasets of obtained for each fruit growing stage. However, it did not well reproduce the measured values, showing that further studies are necessary.

我们研究了在三个不同的果实生长阶段(结果前、果实发育早期和果实发育晚期),直接施加在梅叶蟹形苹果树(2-3 年树龄的 Malus domestica 'Alps Otome')叶片表面的液滴中所含的稳定 Cs+ 离子的行为。大部分 Cs 在施用后迅速从叶片表面转移到施用的叶片中,然后通过枝条逐渐转移到果实中。到收获时,转移到果实中的铯的平均比例在 11% 到 30% 之间,与果实的生长阶段没有直接关系。在果实发育早期和晚期,叶面吸收 Cs 的速度快于结果期之前,随着果实生长阶段的进展,叶面向果实转移 Cs 的速度也更快。为了描述 Cs 的转移,我们利用各果实生长阶段获得的数据集构建了一个分区模型。然而,该模型并没有很好地再现测量值,这表明有必要进行进一步研究。
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引用次数: 0
An efficient and simple method for enriching metaphase cells for dicentric chromosome assay. 一种高效简便的方法,可富集转移相细胞进行双中心染色体检测。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae048
Ryo Nakayama, Thanh-Mai Tran, Donovan Anderson, Kai Takebayashi, Valerie Swee Ting Goh, Yohei Fujishima, Tomisato Miura

As compared to peripheral blood mononuclear cell (PBMC) culture, a lower mitotic index (MI) is seen in whole blood (WB) culture, but WB can be directly used for culture in dicentric chromosome assay (DCA). The purpose of this study is to develop a simple protocol for metaphase enrichment to improve the metaphase frequency of WB culture. Fixed cells were obtained after performing WB and PBMC cultures for DCA after conventional fixation. An additional low-speed centrifugation of 200 × g for 1 min was performed, separating the fixed cells of WB culture into a pellet and a supernatant fraction. The additional low-speed centrifugation enriched metaphase frequency and provided an MI comparable to the PBMC culture in the pellet fraction. Our study suggests that it is possible to increase the number of metaphase cells on slides using the slow centrifugation method, which could contribute to the efficiency of chromosome aberration analysis in biodosimetry.

与外周血单核细胞(PBMC)培养相比,全血(WB)培养的有丝分裂指数(MI)较低,但 WB 可直接用于双中心染色体测定(DCA)培养。本研究的目的是开发一种简单的有丝分裂期富集方案,以提高 WB 培养的有丝分裂期频率。在进行 WB 和 PBMC 培养后获得固定细胞,在常规固定后进行 DCA 培养。再进行 200 × g 的低速离心 1 分钟,将 WB 培养的固定细胞分离成颗粒和上清部分。额外的低速离心富集了分裂期频率,并在颗粒部分提供了与 PBMC 培养相当的 MI。我们的研究表明,使用慢速离心法可以增加玻片上的移行期细胞数量,这有助于提高生物模拟中染色体畸变分析的效率。
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引用次数: 0
Assessment of air dose distribution in the vertical plane for better occupational exposure management. 评估垂直面的空气剂量分布,改善职业暴露管理。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae150
Tomuhiro Noro, Minoru Osanai, Shota Hosokawa, Maiko Kitajima, Megumi Tsushima, Kohsei Kudo

The International Commission on Radiological Protection recommended a significant reduction of the equivalent dose limit for the eye lens. Reportedly, medical staff in charge of diagnostic imaging procedures may exceed the new dose limits for the eye lens. The use of dosimeters dedicated to the eye lens remains low, and dosimeters for the neck region were often used to assess eye lens doses. However, measurements by neck badges may overestimate or underestimate the recommended eye lens doses because the height of the neck differs from that of the eye. This study aimed to evaluate the air dose distribution in the vertical plane to understand the difference between neck and eye doses. H*(10) in the height of the eye position was 52.8% lower than that in the height of the neck position in the under-table position. Thus, the equivalent eye lens dose evaluated using a neck badge dosimeter may be overestimated.

国际放射防护委员会建议大幅降低眼球镜片的等效剂量限值。据报道,负责诊断成像程序的医务人员可能会超过眼晶状体的新剂量限值。眼晶状体专用剂量计的使用率仍然很低,颈部剂量计通常用于评估眼晶状体剂量。然而,由于颈部的高度与眼部的高度不同,颈部徽章的测量值可能会高估或低估推荐的眼晶状体剂量。本研究旨在评估垂直面的空气剂量分布,以了解颈部和眼部剂量的差异。在台下位置,眼部高度位置的 H*(10) 比颈部高度位置的 H*(10) 低 52.8%。因此,使用颈部徽章剂量计评估的等效眼透镜剂量可能会被高估。
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引用次数: 0
ESR measurement of carbonated hydroxyapatite for dosemeter. 用于剂量计的碳化羟基磷灰石 ESR 测量。
IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1093/rpd/ncae147
Hajime Seito, Eri Yokozuka, Toshitaka Oka, Yoshihiro Kitatsuji, Naotsugu Nagasawa

We have examined a dosimetry characteristic of carbonate hydroxyapatite (CO3HAp), which is a dental bone graft material. The purpose of this work is to investigate the reproducibility and stability of radiation-induced radicals on CO3HAp samples and assess the feasibility of using these materials as dosemeters. CO3HAp samples were exposed to gamma rays with dose range from 10 to 10 000 Gy. The electron spin resonance (ESR) spectra for irradiated samples were measured. Variation of peak-to-peak amplitude of the ESR signal intensity as a function of absorbed dose for CO3HAp was compared with that for alanine dosemeters, suggesting that the CO3HAp sample has a good linear dose response in the range from 10 to 10 000 Gy as well as does the alanine dosemeters.

我们研究了作为牙科植骨材料的碳酸盐羟基磷灰石(CO3HAp)的剂量测定特性。这项工作的目的是研究 CO3HAp 样品上辐射诱导自由基的重现性和稳定性,并评估将这些材料用作剂量计的可行性。CO3HAp 样品暴露于剂量范围为 10 至 10 000 Gy 的伽马射线中。测量了辐照样品的电子自旋共振(ESR)光谱。与丙氨酸剂量计相比,CO3HAp 样品的 ESR 信号强度的峰-峰振幅随吸收剂量的变化情况表明,CO3HAp 样品与丙氨酸剂量计一样,在 10 至 10,000 Gy 的剂量范围内具有良好的线性剂量响应。
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引用次数: 0
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Radiation protection dosimetry
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