Pub Date : 2018-09-15DOI: 10.1183/13993003.CONGRESS-2018.PA3120
Elnaz Firoozehi, Neda Faraji, H. Abtahi, S. Peiman
Background:Hyponatremia is associated with adverse outcome in some cardiopulmonary disease such as left ventricular failure. Probable mechanism in this situation is neurohumoral activation due to hemodynamic instability. However the usefulness of serum sodium level in acute pulmonary embolism (PE) is less well studied. Objectives: To evaluate the prognostic value of hyponatremia in acute PE. Methods: From Oct 2016 to Dec 2017, by a prospective study, consecutive patients presented to ED with confirmed acute PE were included. Those with history of CHF and diuretic use were excluded. The patients were divided into two groups: hyponatremic (Na Results: Finally, 121 patients completed the follow-up (Age: 54.2±17.8, M/F: 66/55). Hyponatremic patients had significant higher on-admission PESI score and 30-day mortality rate than non-hyponatremic group (110.5±39.3 vs 92.8±40.2, P=0.03 and 32.6% vs 12.3%, p Conclusions: Hyponatremia in patients with acute PE is associated with adverse outcome in terms of in-hospital clinical severity and 30-day mortality rate.
背景:低钠血症与一些心肺疾病(如左心室衰竭)的不良预后相关。在这种情况下,可能的机制是由于血流动力学不稳定引起的神经体液激活。然而,血清钠水平在急性肺栓塞(PE)中的作用研究较少。目的:探讨低钠血症对急性肺心病的预后价值。方法:2016年10月至2017年12月,通过一项前瞻性研究,纳入了连续出现ED并确诊急性PE的患者。排除有CHF病史和使用利尿剂的患者。结果:121例患者完成随访(年龄:54.2±17.8,男/女:66/55)。低钠血症患者入院时PESI评分和30天死亡率显著高于非低钠血症组(110.5±39.3 vs 92.8±40.2,P=0.03和32.6% vs 12.3%, P)。结论:急性PE患者低钠血症与院内临床严重程度和30天死亡率相关。
{"title":"The value of on-admission serum Sodium level on 30-day outcome in acute pulmonary embolism","authors":"Elnaz Firoozehi, Neda Faraji, H. Abtahi, S. Peiman","doi":"10.1183/13993003.CONGRESS-2018.PA3120","DOIUrl":"https://doi.org/10.1183/13993003.CONGRESS-2018.PA3120","url":null,"abstract":"Background:Hyponatremia is associated with adverse outcome in some cardiopulmonary disease such as left ventricular failure. Probable mechanism in this situation is neurohumoral activation due to hemodynamic instability. However the usefulness of serum sodium level in acute pulmonary embolism (PE) is less well studied. Objectives: To evaluate the prognostic value of hyponatremia in acute PE. Methods: From Oct 2016 to Dec 2017, by a prospective study, consecutive patients presented to ED with confirmed acute PE were included. Those with history of CHF and diuretic use were excluded. The patients were divided into two groups: hyponatremic (Na Results: Finally, 121 patients completed the follow-up (Age: 54.2±17.8, M/F: 66/55). Hyponatremic patients had significant higher on-admission PESI score and 30-day mortality rate than non-hyponatremic group (110.5±39.3 vs 92.8±40.2, P=0.03 and 32.6% vs 12.3%, p Conclusions: Hyponatremia in patients with acute PE is associated with adverse outcome in terms of in-hospital clinical severity and 30-day mortality rate.","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79688913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.congress-2018.pa3131
Demin Aa, V. Drobysheva
{"title":"Pulmonary onset and complications of intravenous drug users infective endocarditis","authors":"Demin Aa, V. Drobysheva","doi":"10.1183/13993003.congress-2018.pa3131","DOIUrl":"https://doi.org/10.1183/13993003.congress-2018.pa3131","url":null,"abstract":"","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"8 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78644513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.congress-2018.oa3596
Xiaoming Zhou, Gang Hou
{"title":"A radiomics nomogram based on CT pulmonary angiographic data for predicting adverse outcomes in non-high-risk acute pulmonary embolism patients","authors":"Xiaoming Zhou, Gang Hou","doi":"10.1183/13993003.congress-2018.oa3596","DOIUrl":"https://doi.org/10.1183/13993003.congress-2018.oa3596","url":null,"abstract":"","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"27 Suppl 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80306440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.congress-2018.oa3805
R. D. Domenica, A. Corsico, A. D'armini, Valentina Conio, A. Grosso, E. Gini, F. Albicini, M. Pin, A. Sciortino, S. Ghio, C. Klersy, I. Cerveri
{"title":"Persistent exercise limitation after successful pulmonary endoarterectomy: frequency and determinants","authors":"R. D. Domenica, A. Corsico, A. D'armini, Valentina Conio, A. Grosso, E. Gini, F. Albicini, M. Pin, A. Sciortino, S. Ghio, C. Klersy, I. Cerveri","doi":"10.1183/13993003.congress-2018.oa3805","DOIUrl":"https://doi.org/10.1183/13993003.congress-2018.oa3805","url":null,"abstract":"","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86482359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.congress-2018.oa3802
A. A. A. Cordeiro, Pulcheri Roberta, C. Loureiro, E. Ferreira, A. Cepêda, C. Messina, R. K. Oliveira, Verrastro Carlos, L. Nery, J. Ota-Arakaki
{"title":"Tomographic features associated with excessive ventilatory responses during exercise in chronic pulmonary thromboembolic hypertension","authors":"A. A. A. Cordeiro, Pulcheri Roberta, C. Loureiro, E. Ferreira, A. Cepêda, C. Messina, R. K. Oliveira, Verrastro Carlos, L. Nery, J. Ota-Arakaki","doi":"10.1183/13993003.congress-2018.oa3802","DOIUrl":"https://doi.org/10.1183/13993003.congress-2018.oa3802","url":null,"abstract":"","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85479903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.congress-2018.oa3800
A. Zamani, Adil Zamani, C. Korkmaz, Ş. Yosunkaya, M. Yıldırım
{"title":"Variants of genes related to cardiovascular disease in patients with pulmonary thromboembolism","authors":"A. Zamani, Adil Zamani, C. Korkmaz, Ş. Yosunkaya, M. Yıldırım","doi":"10.1183/13993003.congress-2018.oa3800","DOIUrl":"https://doi.org/10.1183/13993003.congress-2018.oa3800","url":null,"abstract":"","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80303568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.CONGRESS-2018.PA3125
Y. Ateş, Z. Bingol, G. Okumus, O. Arseven
Introduction: Risk of recurrence and bleeding, play a role in considering the optimal duration of treatment. The aim of the study was to determine the frequency of recurrence, risk factors for recurrence and bleeding in cases with VTE. Material-methods:: Study included 412 VTE patients (164 male, 248 female, mean age: 53.5years, follow-up period: 25.3months). Patient9s demographics, risk factors, comorbidities, clinical data, treatment and complications were recorded. Results: There was at least one risk factor in 341 (82.7%) patients and 71 (17.2%) of them were idiopathic. In 76 (18.4%) of the cases VTE recurrence developed. There was no difference between recurrent and non-recurrent groups according to age and sex. There was no relationship between recurrence and mortality. Recurrence was higher in DVT and / or PTE+DVT groups than PTE group (24% vs 14.2%, p=0.007). Idiopathic VTE was higher in recurrent cases (26.3% vs 15.2%, p=0.028). D-dimer levels were higher in recurrent cases at first year control (p=0.034). Hereditary risk factors were higher in recurrent cases (p=0.031). During VTE treatment, 37 (8.9%) of cases had bleeding however major bleeding rate was 3.6%. Duration of anticoagulant was longer in patients who had bleeding (22months vs 12months p=0.047). Bleeding rate was higher in patients with massive PTE (p=0.001) and in elderly patients (≥75years) (p=0.036). Conclusion: In our study, presence of DVT, idiopathic VTE, hereditary risk factors and high D-dimer levels at first year were found as related factors of recurrence. Risk of bleeding increased in recurrent cases, in elderly cases and in cases whose treatment duration was longer in the first VTE event.
简介:复发和出血的风险,在考虑最佳治疗时间时发挥作用。该研究的目的是确定静脉血栓栓塞的复发频率、复发和出血的危险因素。材料-方法:纳入静脉血栓栓塞患者412例,其中男性164例,女性248例,平均年龄53.5岁,随访25.3个月。记录患者的人口统计学、危险因素、合并症、临床资料、治疗和并发症。结果:341例(82.7%)患者存在至少一种危险因素,其中71例(17.2%)为特发性。静脉血栓栓塞复发76例(18.4%)。复发组和非复发组在年龄和性别上没有差异。复发和死亡率之间没有关系。DVT组和/或PTE+DVT组复发率高于PTE组(24% vs 14.2%, p=0.007)。复发患者的特发性静脉血栓栓塞发生率更高(26.3% vs 15.2%, p=0.028)。d -二聚体水平在复发病例中高于第一年对照组(p=0.034)。复发患者的遗传危险因素较高(p=0.031)。静脉血栓栓塞治疗期间出血37例(8.9%),大出血率3.6%。出血患者抗凝时间更长(22个月vs 12个月p=0.047)。出血率在大量PTE患者(p=0.001)和老年患者(≥75岁)中较高(p=0.036)。结论:在我们的研究中,发现DVT的存在、特发性静脉血栓栓塞、遗传危险因素和第一年高d -二聚体水平是复发的相关因素。复发病例、老年病例和首次静脉血栓栓塞治疗时间较长的病例出血风险增加。
{"title":"Factors affecting recurrence and bleeding complications in patients withvenous thromboembolism","authors":"Y. Ateş, Z. Bingol, G. Okumus, O. Arseven","doi":"10.1183/13993003.CONGRESS-2018.PA3125","DOIUrl":"https://doi.org/10.1183/13993003.CONGRESS-2018.PA3125","url":null,"abstract":"Introduction: Risk of recurrence and bleeding, play a role in considering the optimal duration of treatment. The aim of the study was to determine the frequency of recurrence, risk factors for recurrence and bleeding in cases with VTE. Material-methods:: Study included 412 VTE patients (164 male, 248 female, mean age: 53.5years, follow-up period: 25.3months). Patient9s demographics, risk factors, comorbidities, clinical data, treatment and complications were recorded. Results: There was at least one risk factor in 341 (82.7%) patients and 71 (17.2%) of them were idiopathic. In 76 (18.4%) of the cases VTE recurrence developed. There was no difference between recurrent and non-recurrent groups according to age and sex. There was no relationship between recurrence and mortality. Recurrence was higher in DVT and / or PTE+DVT groups than PTE group (24% vs 14.2%, p=0.007). Idiopathic VTE was higher in recurrent cases (26.3% vs 15.2%, p=0.028). D-dimer levels were higher in recurrent cases at first year control (p=0.034). Hereditary risk factors were higher in recurrent cases (p=0.031). During VTE treatment, 37 (8.9%) of cases had bleeding however major bleeding rate was 3.6%. Duration of anticoagulant was longer in patients who had bleeding (22months vs 12months p=0.047). Bleeding rate was higher in patients with massive PTE (p=0.001) and in elderly patients (≥75years) (p=0.036). Conclusion: In our study, presence of DVT, idiopathic VTE, hereditary risk factors and high D-dimer levels at first year were found as related factors of recurrence. Risk of bleeding increased in recurrent cases, in elderly cases and in cases whose treatment duration was longer in the first VTE event.","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75174268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.CONGRESS-2018.PA3118
K. Bartolo, C. Cannataci, C. Zammit, J. Azzopardi, J. Cassar, P. Grech, G. Borg, Brendan Caruana Montaldo
{"title":"Can age-adjusted D-dimer be used to decrease the CTPA burden in a general hospital?","authors":"K. Bartolo, C. Cannataci, C. Zammit, J. Azzopardi, J. Cassar, P. Grech, G. Borg, Brendan Caruana Montaldo","doi":"10.1183/13993003.CONGRESS-2018.PA3118","DOIUrl":"https://doi.org/10.1183/13993003.CONGRESS-2018.PA3118","url":null,"abstract":"","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75615388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.CONGRESS-2018.OA3598
C. Goyard, B. Côté, V. Looten, A. Roche, J. Pastre, J. Marey, B. Planquette, G. Meyer, O. Sanchez
{"title":"Determinants and prognostic impact of diagnostic delay in pulmonary embolism","authors":"C. Goyard, B. Côté, V. Looten, A. Roche, J. Pastre, J. Marey, B. Planquette, G. Meyer, O. Sanchez","doi":"10.1183/13993003.CONGRESS-2018.OA3598","DOIUrl":"https://doi.org/10.1183/13993003.CONGRESS-2018.OA3598","url":null,"abstract":"","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"173 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78912292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-15DOI: 10.1183/13993003.congress-2018.oa3804
J. Catella-Chatron, A. Merah, E. Magalhaes, N. Moulin, S. Accassat, C. Duvillard, P. Mismetti, L. Bertoletti
{"title":"Frequency of chronic thromboembolic pulmonary hypertension screening after pulmonary embolism in cancer patients.","authors":"J. Catella-Chatron, A. Merah, E. Magalhaes, N. Moulin, S. Accassat, C. Duvillard, P. Mismetti, L. Bertoletti","doi":"10.1183/13993003.congress-2018.oa3804","DOIUrl":"https://doi.org/10.1183/13993003.congress-2018.oa3804","url":null,"abstract":"","PeriodicalId":20797,"journal":{"name":"Pulmonary embolism","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89417922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}