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Management and coping of dental clinics during the COVID-19 pandemic: a cross-sectional study in three countries. COVID-19大流行期间牙科诊所的管理和应对:三个国家的横断面研究
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-22 DOI: 10.3290/j.qi.b6153663
Gisela Berenstein Ajzman, Shada Fadela, Patricia Batista Lopes do Nascimento, Leticia Maria Correia Pimentel, Sonu Acharya, Sarit Naishlos, Sigalit Blumer

Objective: To examine the changes in dental practice in response to the COVID-19 pandemic 6 to 12 months after its outbreak.

Method and materials: An electronic survey was disseminated among dental practitioners from Brazil, India, and Israel between August 2020 and April 2021. The questionnaire comprised two sections: 1) participant demographics and participant characteristics, and 2) working conditions during the COVID-19 pandemic.

Results: In total, 979 respondents (72.6% females) completed the questionnaire (56.9% Brazilian, 24.6% Israeli, 18.5% Indian). About two-thirds of Brazilian (62.1%) and Indian respondents (68.4%) and 54.8% of Israeli respondents provided emergency care during the first wave of the pandemic; a fifth or lower treated patients with COVID-19. Most respondents reported changes in their appointment management, along with decreased income compared to the period before the pandemic, attributed to the decrease in the number of treatments together with increased expenses, mainly on equipment, protection, and disinfection. More than half of Indian and Israeli respondents reported that guidelines provided by the Ministry of Health were very clear, compared to 31% of Brazilian dental practitioners. Only 35.8% of Brazilian respondents reported that they had received clear instructions regarding conduct in the clinic compared to 69% and 72% of Indian and Israeli respondents, respectively.

Conclusions: Dental practitioners from three very different countries around the world faced similar challenges in their practices during the first months of the COVID-19 pandemic. Although most participants adjusted to the alterations in their professional routines necessitated by pandemic-related restrictions, these modifications also resulted in shifts in clinicians' workloads, elevated expenditures, and reduced income. Public health guidelines provided to dental practices by the authorities were not always clear. Understanding these challenges and how to deal with them should help cope better with future worldwide crises.

目的:了解2019冠状病毒病(COVID-19)大流行6 ~ 12个月后牙科诊疗的变化。方法和材料:于2020年8月至2021年4月对巴西、印度和以色列的牙科从业者进行电子调查。调查问卷包括两个部分:1)参与者人口统计和参与者特征,2)COVID-19大流行期间的工作条件。结果:共有979名受访者(72.6%为女性)完成问卷调查,其中巴西人占56.9%,以色列人占24.6%,印度人占18.5%。大约三分之二的巴西(62.1%)和印度(68.4%)受访者以及54.8%的以色列受访者在大流行的第一波期间提供了紧急护理;五分之一或更低的COVID-19患者接受了治疗。大多数答复者报告说,与大流行前相比,他们的预约管理发生了变化,收入也有所减少,原因是治疗次数减少,同时主要在设备、防护和消毒方面的费用增加。一半以上的印度和以色列答复者报告说,卫生部提供的指导方针非常明确,而巴西牙科从业人员的这一比例为31%。只有35.8%的巴西受访者报告说,他们收到了关于诊所行为的明确指示,而印度和以色列受访者的这一比例分别为69%和72%。结论:在2019冠状病毒病大流行的头几个月,来自世界上三个截然不同国家的牙科医生在执业过程中面临着类似的挑战。虽然大多数参与者都适应了与大流行有关的限制所要求的专业惯例的改变,但这些改变也导致临床医生工作量的变化、支出的增加和收入的减少。当局为牙科诊所提供的公共卫生准则并不总是明确的。了解这些挑战以及如何应对它们应该有助于更好地应对未来的全球危机。(精粹Int 2025;56:2-16;doi : ##.####/ j.qi.a # # # # #)。
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引用次数: 0
Daily supervised toothbrushing in kindergartens: second and third years of 'Smiles' oral health promotion program among preschool children. 幼儿园每日监督刷牙:学龄前儿童“微笑”口腔健康促进计划的第二年和第三年。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-22 DOI: 10.3290/j.qi.b6156591
Hadas Goldberg, Guy Tobias, Zvi Feine, Merav Kynan Orenstein, Harold Sgan-Cohen, Jonathan Mann, Avi Zini, Nirit Yavnai, Yuval Vered

Objectives: To describe the second and third years of 'Smiles,' with the objective of demonstrating feasible, practical, and realistic aspects of enhancement of daily toothbrushing skills and integration of a supportive environment of daily supervised toothbrushing in kindergartens.

Method and materials: In total, 36 out of 180 kindergartens (20%) across Israel that participated in the first year of the program, took part in the second and third years of the program. Eighteen kindergartens served as the study group with a supervised toothbrushing routine, and 18 kindergartens served as controls without a supervised toothbrushing routine. Toothbrushing skills were recorded using the Simmons Index at baseline among 3-year-old children, after 1 year, and finally after 2 years among 5-year-old children. Early childhood caries was evaluated by decayed, missing, and filled tooth (dmft) Index among 5-year-old children at the end of the program. Statistical analysis included the chi-square test, Mann-Whitney test, and a generalized linear model.

Results: 1,028 preschool children (503 of them in the daily toothbrushing kindergartens), their parents, and their educational staff took part in the program. The average number of brushing days per week at the daily supervised toothbrushing kindergartens met the desired threshold of 3 days a week. The average daily percentage of preschool children brushing their teeth exceeded 80%. High levels of program cooperation and satisfaction (> 80%) were recorded. Children in toothbrushing kindergartens demonstrated statistically significant three-fold higher levels of toothbrushing skills improvement as compared to children in control kindergartens (33% compared to 11%, respectively; P .001). Being in the Jewish sector and participation in the daily toothbrushing program were revealed as predictors of low dft scores among 5-year-old children (odds ratio [OR] = 0.320, OR = 0.552, respectively; P .001).

Conclusion: The successful performance and positive atmosphere of 'Smiles' at all its levels (the organization, the staff, the parents, and the children) made this endeavor an example of a large-scale demonstration program with practical and realistic enhancement of daily toothbrushing skills and integration of daily supervised toothbrushing among preschool children in kindergartens. Following the introduction of the 'Smiles' program results to the Ministry of Health in 2017, this service became part of the dental health service for pupils in Israel in 2018.

目的:描述“微笑”的第二年和第三年,目的是展示提高日常刷牙技能的可行性,实用性和现实性,以及在幼儿园中整合日常监督刷牙的支持性环境。方法和材料:在以色列180所幼儿园中,有36所(20%)在项目的第一年参加了项目,在项目的第二年和第三年参加了项目。18所幼儿园作为有监督的刷牙程序的研究组,18所幼儿园作为没有监督的刷牙程序的对照组。用Simmons指数记录3岁儿童、1岁儿童、2岁儿童的基线刷牙技能。在项目结束时,用灵巧指数评估5岁儿童的早期龋齿。统计分析采用卡方检验、Mann-Whitney检验和一般线性模型。结果:1228名(1028名)学龄前儿童(其中503名在日常刷牙幼儿园)及其家长和教育工作人员参与了该项目。每日监督刷牙幼儿园每周平均刷牙天数达到每周3天的预期阈值。学龄前儿童平均每天刷牙的比例超过80%。记录了高水平的项目合作和满意度(bbb80 %)。与对照组相比,有统计学意义的“微笑”幼儿园儿童的刷牙技能水平提高了3倍(33%比11%)。结论:“微笑”在各个层次的成功表现和积极氛围;组织、工作人员、家长和孩子们将这一努力作为一个大规模的示范项目,以实际和现实的方式提高幼儿园学龄前儿童的日常刷牙技能,并融入日常监督刷牙。自2017年向卫生部介绍“微笑”方案成果以来,这项服务已成为2018年以色列学生牙科保健服务的一部分,成为既成事实。
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引用次数: 0
Oral manifestations of Morgellons disease: current understanding of a psychiatric condition - a case series. 莫吉隆斯病的口腔表现:目前对一种精神疾病的认识-一个病例系列。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-22 DOI: 10.3290/j.qi.b6156580
Fabiola Stiernhuvud, Leonardo Caixeta, Manuela Herrera-Martinez, Camilo Ábalos-Labruzzi

Morgellons disease is a rare controversial illness in individuals which is characterized by having a fixed, false belief (delusion) in which they are infested by non-living organisms, despite medical evidence which proves the contrary. The symptoms can appear solely in the oral cavity, a condition that had not previously been described in the dental literature. The underlying mechanisms behind these findings remain unclear; moreover, established diagnostic criteria or effective treatments were unsuccessful. This case report highlights the sensations of feeling hair and threads between the teeth of patients with Morgellons disease, as well as an unusual perception of the tongue and saliva that was self-reported. Conventional medical treatments have not been effective in alleviating those oral symptoms. Taking into account the scarcity of cases in the dental literature, the article underscores the importance of interdisciplinary approaches, in order to enhance diagnosis and treatment by integrating oral and mental health care.

背景:莫吉隆斯病是一种罕见的有争议的个人疾病,其特点是有一种固定的、错误的信念(妄想),认为自己被非生物感染,尽管医学证据证明相反。这些症状可能只出现在口腔,这种情况以前没有在牙科文献中描述过。这些发现背后的潜在机制尚不清楚,此外,既定的诊断标准或有效的治疗方法都不成功。本病例报告强调了莫吉隆斯病患者牙齿间的毛发和线的感觉,以及对舌头和唾液的不寻常的感知。传统的医学治疗在缓解这些口腔症状方面没有效果。考虑到牙科文献中病例的缺乏,本文强调了跨学科方法的重要性,以便通过整合口腔和精神卫生保健来加强诊断和治疗。
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引用次数: 0
Transition of care and dental-medical integration: shared experiences from the complex care center. 护理过渡和牙科医疗整合:来自复杂护理中心的经验分享。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-04-22 DOI: 10.3290/j.qi.b6168799
Furqan Alwaely, Francis Coyne, Adela Planerova
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引用次数: 0
Assessing the efficacy of nonsurgical periodontal treatment on rheumatoid arthritis: an umbrella review. 评估非手术牙周治疗对类风湿关节炎的疗效:综述。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-04-22 DOI: 10.3290/j.qi.b6043843
Xuyan Sheng, Xinjian Ye, Hefei Yuan, Changbo Zheng, Tao Zheng, Qianming Chen, Shuli Deng

Objective: The relationship between periodontitis and rheumatoid arthritis has attracted considerable interest. However, the effect of nonsurgical periodontal treatment (NSPT) on rheumatoid arthritis remains uncertain. This umbrella review aims to consolidate current research to establish a stronger evidence base.

Method and materials: Medline, Embase, and the Cochrane library were searched from inception to August 2024. Two independent reviewers handled study selection, data extraction, and quality assessment (AMSTAR 2). The qualitative analysis covered clinical activity, joint symptoms, inflammatory markers, cytokines, and autoantibodies. Quantitative results for disease activity score 28 (DAS28), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were reported as mean differences with 95% confidence intervals (CIs).

Results: A total of 2,982 records were screened, with 41 full-text articles assessed for eligibility, and 9 selected for evidence synthesis. Qualitative analysis suggests that NSPT may reduce clinical activity in patients with periodontitis and rheumatoid arthritis. Quantitative analysis provided suggestive evidence on the effects of NSPT on DAS28, with the mean difference ranging from -0.38 (95% CI -0.46 to -0.31) to -1.18 (95% CI -1.43 to -0.93). One-third of the included studies were rated as 'high' quality, while another one-third were 'critically low.'

Conclusions: The present evidence suggests that NSPT may provide benefits in managing rheumatoid arthritis symptoms in patients with periodontitis; however, the potential bias of current evidence calls for further rigorous studies. Clinicians should account for the complex interplay between periodontitis and rheumatoid arthritis when devising treatment strategies.

背景:牙周炎与类风湿关节炎(RA)之间的关系引起了人们的广泛关注。然而,非手术牙周治疗(NSPT)对RA的影响仍不确定。本综述旨在巩固目前的研究,以建立更有力的证据基础。方法:检索Medline、Embase和Cochrane图书馆自成立至2024年8月的文献。两名独立审稿人负责研究选择、数据提取和质量评估(AMSTAR-2)。定性分析包括临床活动、关节症状、炎症标志物、细胞因子和自身抗体。疾病活动性评分28 (DAS28)、红细胞沉降率(ESR)和c反应蛋白(CRP)的定量结果报告为平均差异(MD), 95%置信区间(CI)。结果:共筛选了2982条记录,41篇全文文章被评估为合格,9篇被选择用于证据合成。定性分析表明,NSPT可降低牙周炎和RA患者的临床活动。定量分析为NSPT对DAS28的影响提供了提示性证据,MD范围为-0.38 (95%CI: -0.46至-0.31)至-1.18 (95%CI: -1.43至-0.93)。三分之一的纳入研究被评为";高";质量,而另外三分之一是";极低";。结论:目前的证据表明,NSPT可能有助于控制牙周炎患者的症状;然而,现有证据的潜在偏差需要进一步严格的研究。临床医生在制定治疗策略时应考虑到牙周炎和牙周炎之间复杂的相互作用。
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引用次数: 0
Honey in orabase and triamcinolone acetonide for the treatment of atrophic/erosive oral lichen planus: a randomized, blind, controlled, clinical trial. 蜂蜜糖浆膏和曲安奈德治疗萎缩性/糜烂性口腔扁平苔藓:一项随机、盲、对照临床试验
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-04-22 DOI: 10.3290/j.qi.b6043838
Sally Abd El-Meniem El-Haddad

Objective: This study aimed to evaluate the clinical efficacy of an innovative preparation, honey in orabase (50% in 1:1), for treating atrophic/erosive oral lichen planus compared with triamcinolone acetonide 0.1% ointment.

Method and materials: The study involved a total of 60 patients who were randomly divided into three groups: Group I (honey in orabase 50%, 1:1 paste), Group II (triamcinolone acetonide 0.1% ointment), and the control group, Group III (orabase paste). The primary outcome measure was pain, measured on a visual analog scale, and the secondary outcome was the evaluation of the clinical manifestation through an oral lichen planus reduction score assessment.

Results: Compared to Group III, Groups I and II experienced significant reductions in their pain visual analog scale scores and oral lichen planus scores. Participants in Groups I and II reported minimal to no discomfort, with Group I demonstrating the most substantial pain relief.

Conclusion: In comparison to triamcinolone acetonide 0.1% ointment and the control group, the study showed that honey in orabase 50% paste is effective in the reduction of pain and lesion size in patients with atrophic/erosive oral lichen planus. Therefore, as an alternative to utilizing the traditional triamcinolone acetonide 0.1% ointment to treat atrophic/erosive oral lichen planus, honey in orabase 50% paste may be an effective treatment option.

目的:本研究旨在评价一种创新制剂的临床疗效;与0.1%曲安奈德软膏治疗萎缩性/糜烂性口腔扁平苔藓(OLP)的疗效比较。对象和方法:本研究共涉及60例患者,随机分为三组:I组(50%蜂蜜,1:1膏体),II组(0.1%曲安奈德软膏)和对照组III组(orabase膏体)。主要结果测量采用视觉模拟量表(VAS),而次要结果包括通过OLP降低评分评估临床表现。结果:与III组相比,I组和II组的vasp和OLP评分显著降低。第一组和第二组的参与者报告的不适程度最小,甚至没有,而第一组的疼痛缓解程度最大。结论:与0.1%曲安奈德软膏和对照组相比,研究表明50% orabase蜂蜜软膏能有效减轻萎缩性/糜烂性OLP患者的疼痛和病变大小。因此,作为传统的0.1%曲安奈德软膏治疗萎缩性/糜烂性OLP的替代方案,50% orabase蜂蜜软膏可能是一种有效的治疗选择。
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引用次数: 0
Stability of soft tissue augmentation at implant site using volume-stable collagen matrix: 2-year retrospective study. 使用体积稳定的胶原基质在种植体部位增强软组织的稳定性:2年回顾性研究。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-04-22 DOI: 10.3290/j.qi.b6094895
Yaniv Mayer, Leonardo Mancini, Yarden Berg, Jamil A Shibli, Marco Zeltner, Hadar Zigdon Giladi, Eran Gabay

Objective: To evaluate the long-term dimensional stability of dental ridges 2 years after soft tissue augmentation using a porcine-derived volume-stable collagen matrix (VCMX) at healing abutment connections.

Method and materials: A retrospective study was conducted at a private clinic from 2021 to 2023, involving 13 patients who underwent delayed single implant placement in both maxillae and mandible. Three months after implant placement, the buccal soft tissue adjacent to the abutment was augmented with VCMX. Intraoral scans were taken at three points: at implant placement (baseline), 1-month post-grafting, and 24 months after implant loading. Pre-implant CBCT scans were also obtained. Volumetric and profilometric changes were measured at 1, 2, and 3 mm below the mucosal margin by superimposing intraoral and CBCT scans. The Wilcoxon signed-rank test was used for statistical analysis.

Results: All 13 patients completed the 2-year follow-up. Mean volumetric changes at the graft site were + 18.15 ± 15.34 mm3 initially, decreasing by 11.73 ± 21.91 mm3 over 2 years. Profilometric analysis showed increases of 0.72 ± 0.88 mm, 0.54 ± 0.65 mm, and 0.32 ± 0.65 mm at 1, 2, and 3 mm, respectively, 1-month post-grafting. At 24 months, reductions of -0.17 ± 0.77 mm, -0.45 ± 0.58 mm, and -0.48 ± 0.60 mm were recorded.

Conclusions: VCMX use for soft tissue augmentation shows minimal remodeling after 24 months, supporting its efficacy for soft tissue stability in dental implantology. Further long-term studies are recommended. (Quintessence Int 2025;56:274-283; doi: 10.3290/j.qi.b6094895).

目的:评价采用猪源性体积稳定胶原基质(VCMX)软组织增强两年后修复基牙连接时牙脊的长期尺寸稳定性。方法:回顾性研究于2021年至2023年在一家私人诊所进行,涉及13例在上颌和下颌骨延迟单种植的患者。种植体放置3个月后,用VCMX增强临近基牙的颊软组织。在三个点进行口内扫描:种植体放置时(基线)、移植后1个月和种植体装载后24个月。还获得了植入前的锥形束计算机断层扫描(CBCT)。通过叠加口腔内和CBCT扫描,在粘膜边缘以下1mm、2mm和3mm处测量体积和轮廓变化。采用Wilcoxon符号秩检验进行统计分析。结果:13例患者均完成2年随访。移植部位的平均体积变化最初为+18.15±15.34 mm³,两年后减少11.73±21.91 mm³。轮廓分析显示,嫁接后1个月,在1、2和3 mm处,分别增加了0.72±0.88 mm、0.54±0.65 mm和0.32±0.65 mm。24个月时,分别减少-0.17±0.77 mm、-0.45±0.58 mm和-0.48±0.60 mm。结论:VCMX用于软组织隆胸24个月后重塑最小,支持其对种植体软组织稳定性的疗效。建议进一步进行长期研究。
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引用次数: 0
Effect of mandibular exercises in the control of signs and symptoms of temporomandibular disorders: a randomized controlled clinical trial. 下颌运动对颞下颌疾病症状和体征控制的影响:一项随机对照临床试验
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-04-22 DOI: 10.3290/j.qi.b5984433
Wagner Araújo de Negreiros, Romulo Rocha Regis, Ana Cristina de Mello Fiallos, José Eugênio Teixeira Rocha, Isaac Augusto Dantas Nogueira, Paulo Goberlânio de Barros Silva, Raniel Fernandes Peixoto

Objective: To evaluate the effectiveness of mandibular exercises in patients with temporomandibular disorders (TMD) diagnosed by Research Diagnostic Criteria for TMD (RDC/TMD).

Method and materials: Thirty-two patients seeking clinical treatment for TMD were randomly assigned to groups based on the treatment modality: conservative therapy, including occlusal splint therapy and counseling; and mandibular exercises. Muscle and joint pain were assessed using a four-point scale (0 = no pain, 1 = mild pain, 2 = moderate pain, and 3 = severe pain). The maximum unassisted mouth opening (MUMO) was measured in millimeters, both with pain and pain-free. Outcomes were evaluated at baseline (T0) and after a 3-month intervention period (T1).

Results: Both treatments significantly reduced muscle and joint pain intensity at most assessed sites. The reduction in pain with mandibular exercises compared to conservative therapy was statistically significant at the right lateral pole of the temporomandibular joint (P = .048; rank-biserial correlation coefficient [rrb] = 0.348). After 3 months, mandibular exercises resulted in greater pain-free MUMO (T0 vs T1; P = .004; rrb = 0.594), and the increase in MUMO was greater than that observed with conservative therapy (P .001; rrb = 0.742).

Conclusion: Mandibular exercises and conservative therapy similarly reduced palpatory pain, with mandibular exercises showing greater clinical impact at the right lateral pole. Both treatments led to significant improvements in the masseter and temperomandibular joint pole. Mandibular exercises also provided superior, clinically meaningful gains in pain-free MUMO, positioning it as a preferred option when enhancing jaw mobility is a primary goal in TMD management.

目的:评价下颌运动(ME)对颞下颌疾病(TMD)患者的治疗效果(RDC/TMD)。材料与方法:32例临床治疗TMD患者根据治疗方式随机分组:保守治疗(CT),包括咬合夹板治疗和咨询;和我。肌肉和关节疼痛采用4分制进行评估(0 =无痛,1 =轻度疼痛,2 =中度疼痛,3 =重度疼痛)。在无疼痛和有疼痛的情况下,以毫米为单位测量最大无辅助张嘴(MUMO)。在基线(T0)和3个月干预期(T1)后评估结果。结果:两种治疗方法均显著降低了大多数评估部位的肌肉和关节疼痛强度。与CT相比,ME在颞下颌关节(TMJ)右外侧极的疼痛减轻具有统计学意义(p = 0.048;RRB = 0.348)。3个月后,ME导致更大的无痛性MUMO (T0 vs. T1;P = 0.004;rrb = 0.594),且MUMO的升高大于CT (p < 0.001;RRB = 0.742)。结论:ME与CT均可减轻触诊性疼痛,其中ME在右侧极表现出更大的临床影响。两种治疗方法均显著改善了咬肌和颞下颌关节极。ME在无痛性MUMO中也提供了优越的、有临床意义的收益,当增强下颌活动能力是TMD管理的主要目标时,将其定位为首选的选择。
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引用次数: 0
Adhesion of Porphyromonas gingivalis and growth of human gingival fibroblasts on modified titanium dental implant surfaces exhibiting 1,000-nm spikes. 牙龈卟啉单胞菌在改性钛牙种植体表面的粘附和人牙龈成纤维细胞的生长表现出1000 nm的峰值。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-04-22 DOI: 10.3290/j.qi.b5993849
Fariba Ashrafi, Monika Astasov-Frauenhoffer, Elizaveta Fasler-Kan, Sabrina Ruggiero, Roland Steiner, Laurent Marot, Fabien Sanchez, Sebastian Kühl, Michael M Bornstein, Khaled Mukaddam

Objectives: The aim of this study was to assess the antibacterial efficacy of nanostructured dental implant surfaces against Porphyromonas gingivalis, a crucial bacterium in the progression of peri-implantitis. An additional aim was to evaluate the possible effect of the modified implant surface on the viability of human gingival fibroblasts (HGnFs).

Method and materials: As detailed in prior research, sputtering by helium ions was used to produce nanospiked titanium surfaces with a height of 1,000 nm (Ti1000). Smooth machined (Ti machined) and sand-blasted, large-grit, acid-etched titanium disks (TiSLA) served as controls. The antibacterial characteristics of the samples against P gingivalis were evaluated by conventional culturing and SEM. The vitality of HGnFs was assessed using the MTT assay.

Results: Generally, nanostructured Ti1000 surfaces exhibited lower bacterial counts than the two controls (Ti1000 vs TiSLA -36% and Ti1000 vs Ti machined -37%) without being statistically significant. Moreover, the nanosurface did not affect the vitality of HGnFs.

Conclusion: The nanospikes of the modified titanium implant surface did not hinder gingival fibroblasts' vitality or proliferation characteristics. Optimizing the spacing and height parameters of the nanospikes could further improve the antibacterial effects of this unique remodification approach.

目的:本研究的目的是评估纳米结构牙种植体表面对牙龈卟啉单胞菌的抗菌效果,牙龈卟啉单胞菌是种植体周围炎进展中的关键细菌。此外,评估改良种植体表面对人牙龈成纤维细胞(HGnFs)活力的可能影响。方法与材料:如前期研究所述,采用氦离子溅射法制备高度为1000 nm (Ti1000)的纳米尖刺钛表面。光滑加工(Ti machined)和SLA钛盘(TiSLA)作为对照。通过常规培养和扫描电镜观察样品对牙龈卟啉单胞菌的抑菌特性。使用MTT法评估hgnf的活力。结果:一般来说,纳米结构的Ti1000表面的细菌数量比两个对照组(Ti1000 vs TiSLA -36%, Ti1000 vs Ti加工-37%)少,但没有统计学意义。此外,纳米表面不影响hgnf的活力。结论:改良钛种植体表面的纳米尖不影响成纤维细胞的活力和增殖特性。优化纳米尖的间距和高度参数可以进一步提高这种独特的再修饰方法的抗菌效果。
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引用次数: 0
Silver fluoride/potassium iodide application in hypersensitive MIH-affected molars in schoolchildren: prospective clinical evaluation of immediate and mid-term effects in desensitization. 氟化银/碘化钾在学龄儿童过敏mihav磨牙中的应用:脱敏即刻和中期效果的前瞻性临床评价
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-04-22 DOI: 10.3290/j.qi.b6120624
Walaa Basem Ahmed, Ahmad Al Masri, Christian H Splieth, Julian Schmoeckel

Objectives: This single-arm prospective interventional study evaluated the effectiveness of silver-fluoride combined with potassium-iodide (AgF+KI; Riva Star Aqua, SDI) in decreasing hypersensitivity after its application on permanent molars affected by molar incisor hypomineralization (MIH Treatment Need Index [TNI] 3 and 4) immediately (15 minutes) and after 3 months.

Method and materials: In total, 22 children with 53 hypersensitive MIH-affected permanent molars (MIH TNI 3 or 4) underwent AgF+KI application after isolation with cotton rolls. Teeth included had no prior in-office desensitizing agents or sealants within 1 month before recruitment. Hypersensitivity was assessed using a 1-second air blast stimulus at three intervals: baseline, 15 minutes, and 3 months posttreatment (blinded). The response to the air-stimulus was quantified using the Schiff Cold Air Sensitivity Scale (SCASS), and teeth with grades 2 and 3 only were included. Statistical analysis involved the Wilcoxon signed-rank test, Mann-Whitney U test, and Friedman test.

Results: The reported mean SCASS scores declined significantly from 2.5 (± 0.5) at baseline to 1.2 (± 0.9) after 15 minutes and 1.0 (± 1.0) after 3 months (n = 20 patients, n = 49 molars). Molars with SCASS 2 had a statistically significantly lower mean hypersensitivity score (from n = 26 to n = 24) compared to SCASS 3 teeth (from n = 27 to n = 19) at the subsequent posttreatment evaluation. However, the percentage reduction from baseline was not significant. Additionally, the reduction in hypersensitivity after AgF+KI application was almost identical for treated (desensitizing agent >1 month prior enrolment) and untreated molars.

Conclusion: AgF+KI is an effective and simple desensitizer providing instant and mid-term relief in schoolchildren with hypersensitive MIH-molars.

目的:本单臂前瞻性介入研究评估氟化银联合碘化钾(AgF+KI;Riva Star Aqua®,SDI Limited)在MIH (MIH- tni 3 & 4)影响的恒磨牙上应用后立即(15分钟)和三个月后减少过敏反应。方法:对22例53颗过敏的MIH-TNI-3、4型恒磨牙进行棉签分离后应用AgF+KI。包括的牙齿在招聘前一个月内没有使用过脱敏剂或密封剂。超敏反应在三个间隔进行评估,分别是:基线、15分钟和治疗后3个月(盲法)。采用SCASS测试对空气刺激反应进行量化,仅纳入2级和3级牙齿。统计分析采用Wilcoxon sign -rank检验、Mann-Whitney U检验和Friedman检验。结果:报告的平均SCASS评分从基线时的2.51分显著下降到15分钟后的1.15分和3个月后的0.98分(n=20例患者,n=49磨牙)。在随后的治疗后评估中,SCASS 2牙的平均过敏评分(从n=26到n=24)低于SCASS 3牙(从n=27到n=19)。然而,与基线相比减少的百分比并不显著。此外,使用AgF/KI后,治疗磨牙(在入组前1个月使用脱敏剂bbb10)和未治疗磨牙的超敏反应减少几乎相同。结论:AgF+KI是一种简便、有效的脱敏剂,可对小学生高敏mih磨牙起到即时和中期缓解作用。
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Quintessence international
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