Objective: The objective of this study was to compare the clinical efficacy of amniotic membrane (AM) and collagen membrane (CM), both used in conjunction with coronally advanced flaps (CAFs), in the treatment of gingival recession, assessing their ability to achieve root coverage and improve periodontal health. The primary outcome measure was the percentage of root coverage. Secondary outcomes included recession height, recession width, keratinized tissue width, probing depth, and clinical attachment level.
Method and materials: A randomized controlled clinical trial was conducted involving 15 patients with bilateral gingival recessions, resulting in 30 recession sites. Each patient was assigned one control site (CAF + CM) and one test site (CAF + AM) using a coin toss for randomization. The primary outcome measure was the percentage of root coverage. Additional clinical parameters including recession height, recession width, keratinized tissue width, probing depth, and clinical attachment level were recorded using a customized stent. Postoperative evaluations were performed at 3 months.
Results: Both groups demonstrated significant improvements in recession height, recession width, keratinized tissue width, probing depth, and clinical attachment level from baseline to 3 months (P .001). At the 3-month follow-up, the test group achieved a mean recession height reduction of 2.8 ± 1.0 mm and a mean recession width reduction of 3.6 ± 1.4 mm, while the control group achieved reductions of 2.7 ± 1.1 mm and 3.6 ± 1.3 mm, respectively. The mean percentage of root coverage was 90.3 ± 14.5% (recession height) and 81.8 ± 23.2% (recession width) in the test group and 90.0 ± 16.7% (recession height) and 83.7 ± 21.9% (recession width) in the control group, with no statistically significant differences between groups (P > .05).
Conclusion: Both amniotic membrane and collagen membrane, when used in combination with coronally advanced flaps, are effective in managing gingival recession, yielding comparable root coverage and periodontal improvements. The study is limited by its short follow-up period and lack of histologic assessment. However, AM may offer practical advantages such as easier handling, reduced patient morbidity, and cost-effectiveness.
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