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Association Between Global Sleep Quality and Coronary Microvascular Function in Male Physicians With Occupational Burnout. 职业倦怠男性医师整体睡眠质量与冠状动脉微血管功能的关系
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-01 Epub Date: 2023-11-17 DOI: 10.1097/PSY.0000000000001269
Roland von Känel, Mary Princip, Sarah A Holzgang, Alexia Rossi, Andreas A Giannopoulos, Ronny R Buechel, Claudia Zuccarella-Hackl, Aju P Pazhenkottil

Objective: Occupational burnout has been associated with an increased risk of coronary heart disease, although the mechanisms involved are elusive. We investigated whether poor global sleep quality is associated with impaired coronary microvascular function in male physicians, a professional group at increased risk of burnout.

Methods: Study participants were 30 male physicians with clinical burnout and 30 controls without burnout defined by the Maslach Burnout Inventory. Global sleep quality was measured with the Pittsburgh Sleep Quality Index (PSQI). Endothelium-dependent (cold pressor test) and endothelium-independent (adenosine challenge) coronary microvascular functions were quantified with myocardial perfusion positron emission tomography. In multivariable analyses, the interaction between burnout and the PSQI global score was regressed on measures of coronary microvascular function, adjusting for age, body mass index, physical activity, alcohol consumption, and main effects of burnout and PSQI score.

Results: The prevalence of poor sleepers (PSQI score >5) was 40% in the burnout group and 10% in the control group. Adjusting for covariates, burnout-by-global PSQI score interactions were observed for myocardial blood flow (MBF) at rest ( r partial = -0.30, p = .025), endothelium-dependent coronary flow reserve ( r partial = -0.26, p = .062), MBF response ( r partial = -0.30, p = .028), and hyperemic MBF ( r partial = -0.34, p = .012). The global PSQI score was inversely associated with these MBF measures in the burnout group relative to the control group. No significant interactions emerged for endothelium-independent MBF.

Conclusions: In male physicians with occupational burnout, poor global sleep quality was associated with reduced endothelium-dependent coronary microvascular function, suggesting a mechanism by which burnout may affect cardiovascular health.

目的:职业倦怠与冠心病风险增加有关,但其机制尚不明确。我们调查了男性医生整体睡眠质量差是否与冠状动脉微血管功能受损有关,这是一个职业群体,倦怠风险增加。方法:研究对象为30名有临床职业倦怠的男性医生和30名没有职业倦怠的对照组(由Maslach职业倦怠量表定义)。采用匹兹堡睡眠质量指数(PSQI)测量全球睡眠质量。心肌灌注正电子发射断层扫描定量检测内皮依赖性(冷压试验)和内皮非依赖性(腺苷挑战)冠状动脉微血管功能。在多变量分析中,通过冠状动脉微血管功能测量、年龄、体重指数、体力活动、酒精消耗以及倦怠和PSQI评分的主要影响,对倦怠与PSQI总分之间的相互作用进行了回归。结果:倦怠组睡眠质量差(PSQI评分bb50)发生率为40%,对照组为10%。调整协变量后,观察到静息时心肌血流量(MBF)与总体PSQI评分的相互作用(r偏= -)。30, p = 0.025),内皮依赖性冠状动脉血流储备(r偏= -。26, p = 0.062), MBF反应(r偏= -。30, p = 0.028)和充血性MBF (r偏= -)。34, p = - 0.012)。与对照组相比,倦怠组整体PSQI得分与MBF测量呈负相关。不依赖内皮的MBF没有明显的相互作用。结论:在职业倦怠的男性医生中,整体睡眠质量差与内皮依赖性冠状动脉微血管功能降低有关,提示职业倦怠可能影响心血管健康的机制。
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引用次数: 0
High Heart Rate Variability Buffers the Effect of Attachment Insecurity on Sleep Quality. 高心率变异性可缓冲依恋不安全感对睡眠质量的影响。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-01 Epub Date: 2024-03-04 DOI: 10.1097/PSY.0000000000001295
Jensine Paoletti-Hatcher, Daniel L Argueta, E Lydia Wu-Chung, Michelle A Chen, Ryan L Brown, Angie S LeRoy, Kyle W Murdock, Julian F Thayer, Christopher P Fagundes

Objective: Sleep quality is an important health-protective factor. Psychosocial factors, including attachment orientation, may be valuable for understanding who is at risk of poor sleep quality and associated adverse health outcomes. High attachment anxiety is reliably associated with adverse health outcomes, whereas high attachment avoidance is associated with adverse health outcomes when co-occurring with poor self-regulatory capacity, indexed by heart rate variability (HRV). We examined the associations between attachment anxiety, attachment avoidance, HRV, and sleep quality.

Methods: Using longitudinal data from a sample of 171 older adults measured four times over 1 year ( M = 66.18 years old; 67.83% women), we separated the between-person variance (which we call "trait") and within-person variance (which we call "state") for attachment anxiety, attachment avoidance, and HRV (via the root mean square of successive differences). Sleep quality was measured with the Pittsburgh Sleep Quality Index.

Results: Higher trait attachment anxiety was associated with poorer global sleep quality ( B = 0.22, p = .005). Higher state attachment avoidance was associated with poorer sleep quality ( B = -0.13, p = .01), except for those with higher trait HRV. Higher state attachment anxiety was associated with poorer sleep quality ( B = -0.15, p = .002), except for those with higher or mean trait HRV. Higher trait attachment anxiety was associated with poorer sleep quality ( B = -0.31, p = .02), except for those with higher trait HRV.

Conclusions: High trait HRV mitigated the adverse effects of attachment insecurity on sleep quality. Our results suggest that people with high trait HRV had greater self-regulation capacity, which may enable them to enact emotion regulation strategies effectively.

目的:睡眠质量是重要的健康保护因素:睡眠质量是一个重要的健康保护因素。包括依恋取向在内的社会心理因素对于了解哪些人有睡眠质量差和相关不良健康后果的风险可能很有价值。高度依恋焦虑与不良健康后果有可靠的相关性,而高度依恋回避与不良自我调节能力(以心率变异性(HRV)为指标)同时存在时,则与不良健康后果相关。我们研究了依恋焦虑、依恋回避、心率变异和睡眠质量之间的关联:利用对 171 名老年人(男 = 66.18 岁;67.83% 为女性)一年内进行四次测量的纵向数据,我们分离了依恋焦虑、依恋回避和心率变异的人际变异(我们称之为 "特质")和人内变异(我们称之为 "状态")(通过连续差异的均方根)。睡眠质量通过匹兹堡睡眠质量指数进行测量:结果:特质依恋焦虑越高,整体睡眠质量越差(B = 0.22,p = .005)。较高的状态依恋回避与较差的睡眠质量有关(B = -0.13,p = .01),特质心率变异较高的人除外。较高的状态依恋焦虑与较差的睡眠质量有关(B = -0.15,p = .002),但特质心率变异较高或平均的人除外。特质依恋焦虑越高,睡眠质量越差(B = -0.31,p = .02),特质心率变异越高的人除外:结论:高特质心率变异减轻了依恋不安全感对睡眠质量的不利影响。我们的研究结果表明,特质心率变异高的人具有更强的自我调节能力,这可能使他们能够有效地实施情绪调节策略。
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引用次数: 0
Dynamic Associations Among Sleep, Emotion Dysregulation, and Desire to Live in a Perinatal Sample. 围产期样本中睡眠、情绪失调和求生欲望之间的动态关联
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-01 Epub Date: 2024-03-04 DOI: 10.1097/PSY.0000000000001297
Parisa R Kaliush, Jonathan E Butner, Paula G Williams, Elisabeth Conradt, Sheila E Crowell

Objective: The present study prospectively examined dynamic associations among sleep, emotion dysregulation, and desire to live during the perinatal transition, as it was theorized that these factors may contribute to the emergence of postpartum suicide risk.

Method: Ninety-four women ( Mage = 29.2 years; 23.4% Latina) wore wrist actigraphs and completed twice daily surveys for 7 days during the third trimester of pregnancy, 6 weeks postpartum, and 4 months postpartum. Multilevel, change-as-outcome models were built to examine changes in attractor dynamics among sleep, emotion dysregulation, and desire to live, as well as if sleep-emotion dysregulation dynamics differed based on participants' desires to live.

Results: From pregnancy to 6 weeks postpartum, emotion dysregulation ( B = -0.09, p = .032) and desire to live ( B = -0.16, p < .001) exhibited more stable temporal patterns around higher emotion dysregulation and lower desire to live. Compared to women who reported consistently high desires to live, those who experienced fluctuations in their desires to live exhibited lower, more stable sleep efficiency during pregnancy ( B = -0.90, p < .001). At 4 months postpartum, those with fluctuating desires to live exhibited a coupling dynamic whereby low sleep efficiency predicted increases in emotion dysregulation ( B = -0.16, p = .020).

Conclusions: This study was the first to examine nonlinear dynamics among risk factors for postpartum suicide, which may be evident as early as pregnancy and 6 weeks postpartum. Sleep health, in particular, warrants further exploration as a key susceptibility factor in the emergence of postpartum suicide risk.

Preregistration: Open Science Framework ( https://osf.io/qxb75/?view_only=799ffe5c048842dfb89d3ddfebaa420d ).

目的:本研究前瞻性地考察了围产期过渡时期睡眠、情绪失调和求生欲望之间的动态关联:本研究对围产期过渡时期睡眠、情绪失调和求生欲望之间的动态关联进行了前瞻性研究,因为根据推测,这些因素可能会导致产后自杀风险的出现:94名妇女(年龄=29.2岁;23.4%为拉丁裔)在怀孕三个月、产后6周和产后4个月的7天内佩戴腕式活动记录仪并完成每天两次的调查。研究人员建立了多层次的 "变化即结果 "模型,以检验睡眠、情绪失调和求生欲望之间的吸引子动态变化,以及睡眠-情绪失调动态是否因参与者的求生欲望而有所不同:从怀孕到产后 6 周,情绪失调(B = -.09,p = .032)和求生欲望(B = -.16,p < .001)围绕着较高的情绪失调和较低的求生欲望表现出更稳定的时间模式。与求生欲望持续较高的妇女相比,求生欲望波动较大的妇女在怀孕期间的睡眠效率较低,但更稳定(B = -.90,p < .001)。产后4个月时,求生欲望波动的孕妇表现出一种耦合动态,即低睡眠效率预示着情绪失调的增加(B = -.16, p = .020):本研究首次研究了产后自杀风险因素之间的非线性动态关系,这种关系可能早在怀孕和产后 6 周就已显现。睡眠健康作为产后自杀风险出现的一个关键易感因素,尤其值得进一步探讨:开放科学框架 (https://osf.io/qxb75/?view_only=799ffe5c048842dfb89d3ddfebaa420d)。
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引用次数: 0
High-Frequency Heart Rate Variability Is Prospectively Associated With Sleep Complaints in a Healthy Working Cohort. 高频心率变异性与健康工作人群的睡眠不适有前瞻性关联
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-01 Epub Date: 2024-03-04 DOI: 10.1097/PSY.0000000000001302
Matthew R Cribbet, Julian F Thayer, Marc N Jarczok, Joachim E Fischer

Objective: Vagus nerve functioning, as indexed by high-frequency heart rate variability (HF-HRV), has been implicated in a wide range of mental and physical health conditions, including sleep complaints. This study aimed to test associations between HF-HRV measured during sleep (sleep HF-HRV) and subjective sleep complaints 4 years later.

Methods: One hundred forty-three healthy employees (91% male; MAge = 47.8 years [time 2], SD = 8.3 years) of an industrial company in Southern Germany completed the Jenkins Sleep Problems Scale, participated in a voluntary health assessment, and were given a 24-hour ambulatory heart rate recording device in 2007. Employees returned for a health assessment and completed the Jenkins Sleep Problems Scale 4 years later.

Results: Hierarchical regression analyses showed that lower sleep HF-HRV measured in 2007 was associated with higher self-reported sleep complaints 4 years later after controlling for covariates (rab,c = -0.096, b = -0.108, 95% CI, -0.298 to 0.081, ΔR2 = 0.009, p = .050).

Conclusions: These data are the first to show that lower sleep HF-HRV predicted worse sleep 4 years later, highlighting the importance of vagus nerve functioning in adaptability and health.

目的:以高频心率变异性(HF-HRV)为指标的迷走神经功能与包括睡眠不适在内的多种身心健康状况有关。本研究旨在测试睡眠期间测量的高频心率变异性(睡眠高频心率变异性)与 4 年后主观睡眠投诉之间的关联:2007 年,德国南部一家工业公司的 143 名健康员工(91% 为男性;平均年龄 = 47.8 岁[时间 2],标差 = 8.3 岁)填写了詹金斯睡眠问题量表,参加了自愿健康评估,并获得了 24 小时动态心率记录装置。4 年后,员工再次接受健康评估并填写詹金斯睡眠问题量表:层次回归分析表明,在控制协变量后,2007 年测量的较低睡眠 HF-HRV 与 4 年后较高的自我报告睡眠投诉相关(rab,c = -0.096, b = -0.108, 95% CI, -0.298 to 0.081, ΔR2 = 0.009, p = .050):这些数据首次表明,较低的睡眠HF-HRV可预测4年后较差的睡眠,突出了迷走神经功能在适应性和健康方面的重要性。
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引用次数: 0
Objective and Subjective Intraindividual Variability in Sleep: Predisposing Factors and Health Consequences. 睡眠的客观和主观个体差异:诱发因素和健康后果。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-01 Epub Date: 2024-03-04 DOI: 10.1097/PSY.0000000000001301
Chenlu Gao, Michael K Scullin

Objective: We investigated the factors that predispose or precipitate greater intraindividual variability (IIV) in sleep. We further examined the potential consequences of IIV on overall sleep quality and health outcomes, including whether these relationships were found in both self-reported and actigraphy-measured sleep IIV.

Methods: In Study 1, 699 US adults completed a Sleep Intra-Individual Variability Questionnaire and self-reported psychosocial, sleep quality, and health outcomes. In Study 2, 100 university students wore actigraphy and completed psychosocial, sleep, and health surveys at multiple timepoints.

Results: In cross-sectional analyses that controlled for mean sleep duration, predisposing/precipitating factors to greater IIV were being an underrepresented racial/ethnic minority (Study 1: F = 13.95, p < .001; Study 2: F = 7.03, p = .009), having greater stress (Study 2: r values ≥ 0.32, p values ≤ .002) or trait vulnerability to stress (Study 1: r values ≥ 0.15, p values < .001), and showing poorer time management (Study 1: r values ≤ -0.12, p values ≤ .004; Study 2: r values ≤ -0.23, p values ≤ .028). In addition, both studies showed that greater sleep IIV was associated with decreased overall sleep quality, independent of mean sleep duration (Study 1: r values ≥ 0.20, p values < .001; Study 2: r values ≥ 0.33, p values ≤ .001). Concordance across subjective and objective IIV measures was modest ( r values = 0.09-0.35) and similar to concordance observed for subjective-objective mean sleep duration measures.

Conclusion: Risk for irregular sleep patterns is increased in specific demographic groups and may be precipitated by, or contribute to, higher stress and time management inefficiencies. Irregular sleep may lead to poor sleep quality and adverse health outcomes, independent of mean sleep duration, underscoring the importance of addressing sleep consistency.

目的我们研究了导致或加剧睡眠个体内变异性(IIV)的因素。我们进一步研究了个体内变异性对整体睡眠质量和健康结果的潜在影响,包括在自我报告的睡眠个体内变异性和行动仪测量的睡眠个体内变异性中是否发现了这些关系:在研究 1 中,699 名美国成年人填写了睡眠个体内变异性问卷,并自我报告了社会心理、睡眠质量和健康状况。在研究 2 中,100 名大学生在多个时间点佩戴了行动计,并完成了社会心理、睡眠和健康调查:结果:在控制了平均睡眠时间的横截面分析中,导致 IIV 增加的易感/诱发因素包括:少数种族/族裔代表性不足(研究 1:F = 13.95,p < .001;研究 2:F = 7.03,p = .009)、压力较大(研究 2:r 值≥ 0.32,p 值≤ 0.002)或特质易受压力影响(研究 1:rs ≥ 0.15,ps < 0.001),以及时间管理能力较差(研究 1:r = -0.23,p < 0.001;研究 2:rs ≤ -0.26,ps ≤ 0.013)。此外,两项研究均表明,睡眠 IIV 越大,总体睡眠质量越低,这与平均睡眠时间无关(研究 1:rs ≥ 0.20,ps < 0.001;研究 2:rs ≥ 0.33,ps ≤ 0.001)。主观和客观 IIV 测量的一致性不高(rs:0.09-0.35),与主观-客观平均睡眠时间测量的一致性相似:结论:睡眠不规律的风险在特定人口群体中有所增加,可能是由于压力较大和时间管理效率较低造成的。睡眠不规律可能导致睡眠质量差和不良健康后果,这与平均睡眠时间无关,因此强调了解决睡眠一致性问题的重要性。
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引用次数: 0
Article Summaries for May 2024 Psychosomatic Medicine, Volume 86, Issue 4. 2024 年 5 月文章摘要 《心身医学》第 86 卷第 4 期。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-01 DOI: 10.1097/PSY.0000000000001318
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引用次数: 0
Exploring the Interplay Between Stress, Sleep, and Health: A Special Issue Commemorating the Contributions of Dr. Martica Hall. 探索压力、睡眠与健康之间的相互作用:纪念 Martica Hall 博士贡献的特刊。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-01 DOI: 10.1097/PSY.0000000000001309
Wendy M Troxel, Julian F Thayer, Daniel J Buysse
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引用次数: 0
Nightly Sleep Predicts Next-Morning Expectations for Stress and Positive Experiences. 夜间睡眠可预测第二天早晨对压力和积极体验的预期。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-01 Epub Date: 2024-03-13 DOI: 10.1097/PSY.0000000000001303
Jin H Wen, Patrick Klaiber, Kate A Leger, Patrick L Hill, Gabrielle N Pfund, Danica C Slavish, Anita DeLongis, Nancy L Sin

Objective: Abundant research has linked nightly sleep as an antecedent of daily psychosocial experiences; however, less is known about sleep's influence on daily expectations of these experiences. Therefore, this research examined the day-to-day associations of sleep quality, duration, and efficiency with next-day expectations for stress(ors) and positive experiences, as well as whether these expectations were related to end-of-day reports of physical symptoms.

Methods: In Study 1, U.S. adults ( n = 354; ages 19 to 74) completed twice-daily diaries for 10 weekdays about sleep, expectations for encountering daily stressors and positive events, and physical symptoms. In Study 2, adults in Canada ( n = 246; ages 25 to 87) wore a sleep watch for 14 consecutive days and completed mobile surveys 5×/day about sleep, stressfulness and pleasantness expectations, and physical symptoms.

Results: Multilevel models indicated that self-reported sleep quality and duration, but not efficiency, were associated with lower next-day expectations for stressors (Study 1) and stressfulness (Study 2). Self-reported sleep quality (Study 1) and all sleep indices (Study 2) predicted greater next-day expectations for positive events and pleasantness, respectively. For actigraphy-assessed sleep (Study 2), only longer-than-usual actigraphic sleep duration was associated with lower stressfulness expectations, whereas both sleep duration and efficiency were positively linked with daily pleasantness expectations. Only pleasantness expectations (Study 2)-but not daily stressfulness and event expectations (Study 1)-predicted end-of-day physical symptoms.

Conclusion: Findings suggest the importance of sleep on expectations of next-day stress and positive experiences, of which may have implications for daily physical health.

研究目的大量研究表明,夜间睡眠是日常社会心理体验的先决条件;然而,人们对睡眠对这些体验的日常预期的影响却知之甚少。因此,本研究考察了睡眠质量、持续时间和效率与第二天对压力(或)和积极体验的预期之间的日常关联,以及这些预期是否与当天结束时的身体症状报告有关:在研究1中,美国成年人(n = 354;年龄在19至74岁之间)在10个工作日内每天两次填写有关睡眠、对日常压力和积极事件的预期以及身体症状的日记。在研究2中,加拿大的成年人(n = 246;年龄在25岁至87岁之间)连续14天佩戴睡眠手表,每天5次完成有关睡眠、压力和愉快预期以及身体症状的移动调查:多层次模型显示,自我报告的睡眠质量和持续时间(而非效率)与第二天较低的压力预期(研究 1)和压力预期(研究 2)有关。自我报告的睡眠质量(研究 1)和所有睡眠指数(研究 2)分别预测了第二天对积极事件和愉快程度的更高期望值。就动图法评估的睡眠而言(研究 2),只有比正常动图法睡眠时间长的睡眠才与较低的压力感预期相关,而睡眠时间和睡眠效率都与每日愉快感预期呈正相关。只有愉快度预期(研究2),而非每日压力性预期和事件预期(研究1)可预测日终身体症状:结论:研究结果表明,睡眠对第二天的压力和积极体验的预期具有重要影响,这可能会对日常身体健康产生影响。
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引用次数: 0
Effects of Chronic Pain Diagnoses on the Antidepressant Efficacy of Transcranial Magnetic Stimulation. 慢性疼痛诊断对经颅磁刺激抗抑郁疗效的影响
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-04-26 DOI: 10.1097/psy.0000000000001311
Houtan Totonchi Afshar, Joel N Fishbein, Erica J Martinez, Gage M Chu, Mohammad A Shenasa, Dhakshin Ramanathan, Matthew S Herbert
Major depressive disorder (MDD) and chronic pain are highly comorbid and bidirectionally related. Repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex is effective in treating MDD, but additional research is needed to determine if chronic pain interferes with rTMS for MDD.
重度抑郁障碍(MDD)和慢性疼痛是高度合并和双向相关的疾病。对背外侧前额叶皮层进行重复经颅磁刺激(rTMS)可有效治疗重度抑郁症,但慢性疼痛是否会干扰经颅磁刺激治疗重度抑郁症还需要进一步研究。
{"title":"Effects of Chronic Pain Diagnoses on the Antidepressant Efficacy of Transcranial Magnetic Stimulation.","authors":"Houtan Totonchi Afshar, Joel N Fishbein, Erica J Martinez, Gage M Chu, Mohammad A Shenasa, Dhakshin Ramanathan, Matthew S Herbert","doi":"10.1097/psy.0000000000001311","DOIUrl":"https://doi.org/10.1097/psy.0000000000001311","url":null,"abstract":"Major depressive disorder (MDD) and chronic pain are highly comorbid and bidirectionally related. Repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex is effective in treating MDD, but additional research is needed to determine if chronic pain interferes with rTMS for MDD.","PeriodicalId":20918,"journal":{"name":"Psychosomatic Medicine","volume":"1 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140806531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceived Stress, Blood Biomarkers, and Cognitive Functioning in Older Adults. 老年人的感知压力、血液生物标志物和认知功能。
IF 3.3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-04-16 DOI: 10.1097/psy.0000000000001317
Pankaja Desai, Ted K S Ng, Kristin R Krueger, Robert S Wilson, Denis A Evans, Kumar B Rajan
There is a substantial gap in knowledge regarding how perceived stress may influence the relationship between serum-measured biomarkers for Alzheimer's disease and cognitive decline.
关于感知压力如何影响阿尔茨海默病血清测量生物标志物与认知能力下降之间的关系,目前还存在很大的知识空白。
{"title":"Perceived Stress, Blood Biomarkers, and Cognitive Functioning in Older Adults.","authors":"Pankaja Desai, Ted K S Ng, Kristin R Krueger, Robert S Wilson, Denis A Evans, Kumar B Rajan","doi":"10.1097/psy.0000000000001317","DOIUrl":"https://doi.org/10.1097/psy.0000000000001317","url":null,"abstract":"There is a substantial gap in knowledge regarding how perceived stress may influence the relationship between serum-measured biomarkers for Alzheimer's disease and cognitive decline.","PeriodicalId":20918,"journal":{"name":"Psychosomatic Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140635362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Psychosomatic Medicine
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