Recent advances in drug delivery and formulation最新文献

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Preface. 前言。

Recent advances in drug delivery and formulation

Pub Date : 2021-01-01 DOI: 10.2174/266738781501210816122827

Stefano Giovagnoli

引用次数: 0

Systematic Patent Review of Nanoparticles in Drug Delivery and Cancer Therapy in the Last Decade. 近十年来纳米颗粒在药物传递和癌症治疗中的系统专利综述。

Recent advances in drug delivery and formulation

Pub Date : 2021-01-01 DOI: 10.2174/1872211314666210521105534

Nur Umairah Ali Hazis, Nagender Aneja, Rajan Rajabalaya, Sheba Rani David

Background: The application of nanotechnology has been considered a powerful platform in improving the current situation in drug delivery and cancer therapy, especially in targeting the desired site of action.

Objective: The main objective of the patent review is to survey and review patents from the past ten years that are related to the two particular areas of nanomedicines.

Methods: The patents related to the nanoparticle-based inventions utilized in drug delivery and cancer treatment from 2010 onwards were browsed in databases like USPTO, WIPO, Google Patents, and Free Patents Online. After conducting numerous screening processes, a total of 40 patents were included in the patent analysis. See the PRISMA checklist 2020 checklist.

Results: Amongst the selected patents, an overview of various types of nanoparticles is presented in this paper, including polymeric, metallic, silica, lipid-based nanoparticles, quantum dots, carbon nanotubes, and albumin-based nanomedicines.

Conclusion: Nanomedicines' advantages include improvements in terms of drug delivery, bioavailability, solubility, penetration, and stability of drugs. It is concluded that the utilization of nanoparticles in medicines is essential in the pursuit of better clinical practice.

背景:纳米技术的应用被认为是改善药物传递和癌症治疗现状的一个强大平台，特别是在靶向作用部位方面。目的:专利审查的主要目的是调查和审查近十年来与纳米药物两个特定领域相关的专利。方法:检索美国专利商标局(USPTO)、世界知识产权组织(WIPO)、Google patents和Free patents Online等数据库，检索2010年以来用于药物输送和癌症治疗的基于纳米颗粒的发明专利。经过多次筛选，共有40项专利被纳入专利分析。参见PRISMA检查表2020检查表。结果:在选定的专利中，本文概述了各种类型的纳米颗粒，包括聚合物，金属，二氧化硅，脂基纳米颗粒，量子点，碳纳米管和白蛋白基纳米药物。结论:纳米药物在给药、生物利用度、溶解度、穿透性、稳定性等方面具有优势。结论是纳米颗粒在药物中的应用对于追求更好的临床实践至关重要。

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引用次数: 3

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