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Cesarean scar pregnancy - case report and review. 剖宫产瘢痕妊娠1例报告及复习。
Pub Date : 2017-01-01
Mateusz Klimek, Grzegorz Cwynar, Igor Bakon, Wojciech Szanecki, Mirosława Mackiewcz, Anna Cygal, Andrzej Witek

Implantation of the embryo in thecesarean section scar is a rare formof ectopic pregnancy. Such conditionposes significant threat to a woman’shealth and live, therefore, requiresaccurate diagnosis and rapid implementationof treatment. The followingarticle presents the case of a patientwith a pregnancy located in the scarafter cesarean section treated in theDepartment of Gynecology and Obstetrics,Medical University of Silesiain Katowice, Faculty of Medicine inKatowice.

剖宫产术中瘢痕植入胚胎是一种罕见的异位妊娠。这种情况对妇女的健康和生命构成重大威胁,因此需要准确诊断和迅速实施治疗。下面的文章介绍了一例在卡托维兹西里西亚医科大学医学院妇产科治疗的剖宫产术后妊娠的病例。
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引用次数: 0
[Estimation of the consumption frequency of high glucose corn syrup by patients with hypertension]. 【高血压患者食用高葡萄糖浆频率的估计】。
Pub Date : 2017-01-01
Aneta Semków-Pochwatko, Katarzyna Stolarz-Skrzypek, Danuta Czarnecka

Hypertension is a major health problemin modern times, due to its highprevalence. This is an important riskfactor for cardiovascular disease, whichare the main cause of death in developedcountries.The component of prevention andnon-pharmacological treatment of hypertensionis a proper diet. More andmore often an adequate supply of sugarsin the diet is emphasized. In recentyears particular attention was paid tothe consumption of HFCS (high fructosecorn syrup), which is present inmany processed foods.The aim of this study was to estimatethe frequency of consumption ofHFCS products among patients with hypertension.

Material and methods: The studyinvolved 108 people diagnosed withhypertension, who attended to the HypertensiveClinic in Krakow. The studywas conducted in the form of FoodFrequency Questionnaire (FFQ) of 24selected beverages and solid products,which are a source of HFCS. In addition,the survey included 6 questions aboutnutrition knowledge on HFCS. The examinationtook place from October 2014.to March 2015.

Results: The vast majority of patientsindicated consumption of productswith HFSC. The most popularproducts proved to be sweets (especiallychocolate bars, wafers) and fruitdrinks and nectars. Frequent consumptionof cola drinks was also observed,which were more often chosen by menthan women. Younger respondents (<55years old) more often than respondentsover 55. years old chose sweets. At thesame time our survey indicated unsatisfactorylevel of nutritional knowledge onHFCS among patients.

Conclusions: The consumption ofHFCS in patients with hypertensionis common, at low knowledge of itsharmful effects on health. Thereforethere is apparent need for dietary educationof patients with hypertension inthis area.

高血压发病率高,是现代社会的一大健康问题。这是心血管疾病的一个重要危险因素,而心血管疾病是发达国家的主要死亡原因。高血压的预防和非药物治疗的组成部分是适当的饮食。人们越来越多地强调饮食中糖的充足供应。近年来,人们特别关注HFCS(高果糖玉米糖浆)的消费,它存在于许多加工食品中。本研究的目的是估计高血压患者食用高果糖玉米糖浆产品的频率。材料和方法:该研究涉及108名在克拉科夫高血压诊所就诊的高血压患者。该研究以食物频率问卷(FFQ)的形式对24种选定的饮料和固体产品进行了调查,这些产品是HFCS的来源之一。此外,调查还包括6个关于HFCS营养知识的问题。考试从2014年10月开始进行。至2015年3月。结果:绝大多数患者表示使用含HFSC的产品。事实证明,最受欢迎的产品是糖果(尤其是巧克力棒、华夫饼)、水果饮料和蜜糖。经常饮用可乐饮料也被观察到,男性比女性更经常选择可乐饮料。结论:高血压患者普遍食用高果糖玉米糖浆,但对其有害健康的认识较低。因此,有必要对该地区的高血压患者进行饮食教育。
{"title":"[Estimation of the consumption frequency of high glucose corn syrup by patients with hypertension].","authors":"Aneta Semków-Pochwatko,&nbsp;Katarzyna Stolarz-Skrzypek,&nbsp;Danuta Czarnecka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypertension is a major health problem\u0000in modern times, due to its high\u0000prevalence. This is an important risk\u0000factor for cardiovascular disease, which\u0000are the main cause of death in developed\u0000countries.\u0000The component of prevention and\u0000non-pharmacological treatment of hypertension\u0000is a proper diet. More and\u0000more often an adequate supply of sugars\u0000in the diet is emphasized. In recent\u0000years particular attention was paid to\u0000the consumption of HFCS (high fructose\u0000corn syrup), which is present in\u0000many processed foods.\u0000The aim of this study was to estimate\u0000the frequency of consumption of\u0000HFCS products among patients with hypertension.</p><p><strong>Material and methods: </strong>The study\u0000involved 108 people diagnosed with\u0000hypertension, who attended to the Hypertensive\u0000Clinic in Krakow. The study\u0000was conducted in the form of Food\u0000Frequency Questionnaire (FFQ) of 24\u0000selected beverages and solid products,\u0000which are a source of HFCS. In addition,\u0000the survey included 6 questions about\u0000nutrition knowledge on HFCS. The examination\u0000took place from October 2014.\u0000to March 2015.</p><p><strong>Results: </strong>The vast majority of patients\u0000indicated consumption of products\u0000with HFSC. The most popular\u0000products proved to be sweets (especially\u0000chocolate bars, wafers) and fruit\u0000drinks and nectars. Frequent consumption\u0000of cola drinks was also observed,\u0000which were more often chosen by men\u0000than women. Younger respondents (<55\u0000years old) more often than respondents\u0000over 55. years old chose sweets. At the\u0000same time our survey indicated unsatisfactory\u0000level of nutritional knowledge on\u0000HFCS among patients.</p><p><strong>Conclusions: </strong>The consumption of\u0000HFCS in patients with hypertension\u0000is common, at low knowledge of its\u0000harmful effects on health. Therefore\u0000there is apparent need for dietary education\u0000of patients with hypertension in\u0000this area.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36041729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Merkel cell carcinoma of the facial skin. Cases presentation and general rules of treatment]. 面部皮肤的默克尔细胞癌。病例介绍和一般治疗规则]。
Pub Date : 2017-01-01
Robert Brodowski, Bartłomiej Startek, Paweł Pakla, Sebastian de Sternberg Stojałowski, Jan Frańczak, Bogumił Lewandowski

Merkel cell carcinoma is an aggressive,malignant, neuroendocrinetumor of the skin. The aim of thestudy is to present the clinical pictures,methods and results of treatmentof MCC in the Clinic of MaxillofacialSurgery in Rzeszow in years2003-2010. Changes were located onthe skin of the face of four patients.All patients were treated surgically,the primary change was removed. Recurrenceafter surgical treatment wasobserved in all patients. The observationsconfirmed the data from theliterature about the incidence of MCCover 75 years of age, aggressivenessand difficulties in treatment of thisdisease.

默克尔细胞癌是一种侵袭性、恶性的皮肤神经内分泌肿瘤。本文旨在介绍2003-2010年在雷泽索夫颌面外科临床治疗MCC的临床表现、方法和结果。改变发生在4名患者的面部皮肤上。所有患者均行手术治疗,切除原发病变。手术治疗后所有患者均出现复发。这些观察结果证实了文献中关于mcc的发病率、侵袭性和治疗困难的数据。
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引用次数: 0
[Surgical treatment results of chronic pericardial tamponade]. [慢性心包填塞的外科治疗结果]。
Pub Date : 2017-01-01
Jarosław Stoliński, Dariusz Plicner, Michał Mędrzyński, Bogusław Kapelak

Objective: To report the efficacy ofchronic pericardial effusion treatmentwith pericardial window creation throughvideo-assisted thoracoscopic surgeryand pericardial drainage througha small subxiphoid incision.

Material and methods: Retrospectiveanalysis of 31 patients after pericardialwindow creation through video-assistedthoracoscopic surgery (PW group) and77 patients where pericardial drainagethrough small subxiphoid incision (PDgroup) was performed. Echocardiographyexaminations were performed todocument pericardial tamponade andpericardial effusion recurrence.

Results: Length of surgery was20.5±5.4 minutes in the PD group and25.8±6.4 minutes in the PW group,p<0.001. Amount of fluid evacuatedfrom pericardium during surgery was483±191 ml and 521±253 ml in PD andPW groups respectively, p=0.654.Postoperative drainage was maintainedlonger (4.3±1.4 days vs. 3.2±1.0,p<0.001) and the amount of fluid drainedafter surgery was higher (497±351ml vs. 309±231 ml, p=0.031) in the PWgroup. The amount of pericardial fluidat the end of hospitalization was statisticallysignificantly higher in the PDgroup compared with the PW group(8.9±4.9 mm vs. 4.9±3.2 mm, p<0.001).Hospital stay was 5.7±2.7 days in thePD group and 6.1±3.4 in the PW group,p=0.112. No patient died duringhospitalization period in either group.Mortality within 30 days after surgerywas 2.6% in the PD and 3.2% in the PWgroup (p=0.642). In the PW group therewere 4 conversions to right minithoracotomydue to dense pleural adhesions.Pericardial effusion recurrenceoccurred in 9 patients (12.0%) in the PDgroup and none was observed (0.0%) inthe PW group (p=0.042) within 30 daysafter surgery.

Conclusion: Pericardial window creationthrough video-assisted thoracoscopicsurgery should be consideredthe preferred method over pericardialdrainage through a small subxiphoidincision for chronic pericardial effusionand pericardial tamponade treatment toreduce the frequency of pericardial effusionreoccurrence.

目的:报道电视胸腔镜下开窗术及剑突下小切口心包引流术治疗慢性心包积液的疗效。材料与方法:回顾性分析31例经视频胸腔镜造窗术(PW组)和77例经剑突下小切口心包引流术(pd组)的病例。超声心动图检查证实心包填塞和心包积液复发。结果:PD组手术时间为20.5±5.4 min, PW组手术时间为25.8±6.4 min。结论:在慢性心包积液治疗和心包填塞治疗中,胸腔镜胸腔镜下心包开窗术优于剑下小切口心包引流术,可减少心包积液的再次发生。
{"title":"[Surgical treatment results of chronic pericardial tamponade].","authors":"Jarosław Stoliński,&nbsp;Dariusz Plicner,&nbsp;Michał Mędrzyński,&nbsp;Bogusław Kapelak","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To report the efficacy of\u0000chronic pericardial effusion treatment\u0000with pericardial window creation through\u0000video-assisted thoracoscopic surgery\u0000and pericardial drainage through\u0000a small subxiphoid incision.</p><p><strong>Material and methods: </strong>Retrospective\u0000analysis of 31 patients after pericardial\u0000window creation through video-assisted\u0000thoracoscopic surgery (PW group) and\u000077 patients where pericardial drainage\u0000through small subxiphoid incision (PD\u0000group) was performed. Echocardiography\u0000examinations were performed to\u0000document pericardial tamponade and\u0000pericardial effusion recurrence.</p><p><strong>Results: </strong>Length of surgery was\u000020.5±5.4 minutes in the PD group and\u000025.8±6.4 minutes in the PW group,\u0000p<0.001. Amount of fluid evacuated\u0000from pericardium during surgery was\u0000483±191 ml and 521±253 ml in PD and\u0000PW groups respectively, p=0.654.\u0000Postoperative drainage was maintained\u0000longer (4.3±1.4 days vs. 3.2±1.0,\u0000p<0.001) and the amount of fluid drained\u0000after surgery was higher (497±351\u0000ml vs. 309±231 ml, p=0.031) in the PW\u0000group. The amount of pericardial fluid\u0000at the end of hospitalization was statistically\u0000significantly higher in the PD\u0000group compared with the PW group\u0000(8.9±4.9 mm vs. 4.9±3.2 mm, p<0.001).\u0000Hospital stay was 5.7±2.7 days in the\u0000PD group and 6.1±3.4 in the PW group,\u0000p=0.112. No patient died during\u0000hospitalization period in either group.\u0000Mortality within 30 days after surgery\u0000was 2.6% in the PD and 3.2% in the PW\u0000group (p=0.642). In the PW group there\u0000were 4 conversions to right minithoracotomy\u0000due to dense pleural adhesions.\u0000Pericardial effusion recurrence\u0000occurred in 9 patients (12.0%) in the PD\u0000group and none was observed (0.0%) in\u0000the PW group (p=0.042) within 30 days\u0000after surgery.</p><p><strong>Conclusion: </strong>Pericardial window creation\u0000through video-assisted thoracoscopic\u0000surgery should be considered\u0000the preferred method over pericardial\u0000drainage through a small subxiphoid\u0000incision for chronic pericardial effusion\u0000and pericardial tamponade treatment to\u0000reduce the frequency of pericardial effusion\u0000reoccurrence.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36044186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The assessment of factors influencing occurrence of adequate interventions of cardiac resynchronization therapy with cardioverter-defibrillator implanted in primary prevention of sudden cardiac death in dilative cardiomyopathy and percentage of biventricular pacing]. [在扩张性心肌病心脏猝死一级预防中植入心律转复除颤器的心脏再同步化治疗适当干预发生的影响因素及双室起搏百分比的评估]。
Pub Date : 2017-01-01
Jacek Lelakowski, Anna Rydlewska, Maria Lelakowska, Joanna Pudło, Justyna Piekarz, Paweł Matusik

The assessment of factors influencingoccurrence of adequate interventionsof cardiac resynchronizationtherapy with cardioverter-defibrillatorimplanted in primary prevention ofsudden cardiac death in dilative cardiomyopathyand percentage of biventricularpacing.

Introduction: The function of cardiacresynchronization therapy withcardioverter-defibrillator (CRT-D) isto treat heart failure (HF) and to treatventricular arrhythmia, if it occurs,with adequate intervention.

Aim: The aim of the study was tofind predictors of adequate interventionsand in how many patients biventricularpacing percentage decreasesduring the follow-up.

Material and methods: The studycomprised of 228 patients (178 M,mean age 66±10, 31-89 years) withimplanted CRTD. The following datawere analyzed: age, sex, presenceof dilative cardiomyopathy, diabetesmellitus, lowered creatinine clearance,atrial fibrillation (AF), LVEF,NYHA class, adequate interventions,number of arrhythmias, pharmacotherapymodifications, device parametersand mortality.

Results: Mean ejection fraction ofthe left ventricle was 20.9±6.4, (10.0-35%). During the mean follow up of770±490 days in 84 (37%) patientsadequate interventions of the deviceoccurred. The adequate interventionsconcerned mainly patients withdiabetes mellitus (HR 2.95), in NYHAclass II, with paroxysmal atrial fibrillation(HR 2.15). In 39 patients (17%) themean percentage of biventricular pacing was below 90%,and in 18 (8%) below 85%.

Conclusions: Diabetes mellitus, NYHA class II, paroxysmal atrial fibrillationhave significantly increased the risk of adequateintervention. The most common causes of loss of biventricularpacing were: inappropriate AV delay, supraventricular arrhythmiasand premature ventricular complexes.A significant correlation between low biventricularpacing percentage and the occurrence of supraventriculararrhythmias and adequate interventions was observed.

扩张性心肌病心源性猝死一级预防中心脏再同步化治疗植入心律转复除颤器适当干预发生率的影响因素评估及双心室起搏百分比导读:心脏转复除颤器(CRT-D)的心脏同步治疗的功能是治疗心力衰竭(HF),如果发生室性心律失常,通过适当的干预治疗。目的:本研究的目的是寻找适当干预的预测因素,以及在随访期间有多少患者双心室起搏百分比下降。材料和方法:本研究纳入了228例植入CRTD的患者(178 M,平均年龄66±10岁,31-89岁)。分析以下数据:年龄、性别、是否存在扩张性心肌病、糖尿病、肌酐清除率降低、心房颤动(AF)、LVEF、NYHA分级、适当的干预措施、心律失常次数、药物治疗修改、器械参数和死亡率。结果:左心室平均射血分数为20.9±6.4,(10.0-35%)。在平均770±490天的随访中,84例(37%)患者对器械进行了充分的干预。适当的干预措施主要涉及糖尿病患者(HR 2.95), nyhacii级,阵发性心房颤动(HR 2.15)。39例(17%)患者双室起搏的平均百分比低于90%,18例(8%)低于85%。结论:糖尿病、NYHA II级、阵发性房颤显著增加适当干预的风险。双室起搏丧失的最常见原因是:不适当的房室延迟、室上心律失常和过早的心室复合体。低双心室起搏率与室上性心律失常的发生有显著的相关性,并观察到适当的干预措施。
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引用次数: 0
Evening not morning plasma cortisol level is higher in women with polycystic ovary syndrome. 多囊卵巢综合征患者的血浆皮质醇水平在晚上高于早上。
Pub Date : 2016-05-13 DOI: 10.1530/ENDOABS.41.GP27
M. Kiałka, Agnieszka Ociepka, T. Milewicz, M. Krzyczkowska-Sendrakowska, Katarzyna Gosztyła, E. Stochmal, M. Lurzyńska, M. Bałajewicz-Nowak
INTRODUCTIONThe aim of our study was to assess the morning and evening cortisol plasma levels in women with polycystic ovary syndrome (PCOS).MATERIAL AND METHOD95 patients gave their informed consent to participate in the study and were divided into 2 groups. Group A consisted of 40 PCOS patients and group B consisted of 55 women without features of PCOS. Between day 5 and 8 of the menstrual cycle, morning (7 am), fasting blood samples were taken for the assessment of luteinizng hormone (LH), follicle stimulating hormone (FSH), estradiol, cortisol, prolactin, thyreotropin (TSH), testosterone and dehydroepeiandrosterone (DHEAS). Evening (5 pm) blood samples were also taken for the evaluation of plasma cortisol levelRESULTSThere were no differences in mean age, body mass index (BMI), FSH, SHBG, PRL, estradiol and TSH levels between group A and group B. Mean plasma LH level was higher in group A compared to group B (10.7 ± 6.8 IU/l vs 6.6 ± 4.5 LU/l, p < 0.02). Mean plasma testosterone and DHEAS levels were also higher in PCOS patients (3.8 ± 0.6 nmol/l vs 1.63 ± 0.6 nmol/l; 427.7 ± 162.9 vs 236.6 ± 97.8 respectively, p < 0.001). Mean evening plasma cortisol level was higher in PCOS patients (11.8 ± 4.1 ug/dl vs 4.7 ± 1.3 ug/dl, p < 0.02). Mean morning plasma cortisol levels did not differ between groups.CONCLUSIONPCOS women showed the increased evening plasma cortisol level with impacted diurnal secretion rate.
本研究的目的是评估多囊卵巢综合征(PCOS)妇女早晚皮质醇血浆水平。材料与方法95例知情同意参加研究的患者分为两组。A组40例PCOS患者,B组55例无PCOS特征的女性。在月经周期的第5天至第8天,早上(早上7点),取空腹血样,评估黄体生成素(LH)、促卵泡激素(FSH)、雌二醇、皮质醇、催乳素、促甲状腺激素(TSH)、睾酮和脱氢表雄酮(DHEAS)。结果A组和B组患者的平均年龄、体重指数(BMI)、FSH、SHBG、PRL、雌二醇和TSH水平均无差异。A组患者的平均血浆LH水平高于B组(10.7±6.8 IU/l vs 6.6±4.5 LU/l, p < 0.02)。PCOS患者的平均血浆睾酮和DHEAS水平也更高(3.8±0.6 nmol/l vs 1.63±0.6 nmol/l;分别为427.7±162.9 vs 236.6±97.8 p < 0.001)。PCOS患者平均夜间血浆皮质醇水平较高(11.8±4.1 ug/dl vs 4.7±1.3 ug/dl, p < 0.02)。各组之间的平均早晨血浆皮质醇水平没有差异。结论pcos妇女夜间血浆皮质醇水平升高,影响其昼夜分泌速率。
{"title":"Evening not morning plasma cortisol level is higher in women with polycystic ovary syndrome.","authors":"M. Kiałka, Agnieszka Ociepka, T. Milewicz, M. Krzyczkowska-Sendrakowska, Katarzyna Gosztyła, E. Stochmal, M. Lurzyńska, M. Bałajewicz-Nowak","doi":"10.1530/ENDOABS.41.GP27","DOIUrl":"https://doi.org/10.1530/ENDOABS.41.GP27","url":null,"abstract":"INTRODUCTION\u0000The aim of our study was to assess the morning and evening cortisol plasma levels in women with polycystic ovary syndrome (PCOS).\u0000\u0000\u0000MATERIAL AND METHOD\u000095 patients gave their informed consent to participate in the study and were divided into 2 groups. Group A consisted of 40 PCOS patients and group B consisted of 55 women without features of PCOS. Between day 5 and 8 of the menstrual cycle, morning (7 am), fasting blood samples were taken for the assessment of luteinizng hormone (LH), follicle stimulating hormone (FSH), estradiol, cortisol, prolactin, thyreotropin (TSH), testosterone and dehydroepeiandrosterone (DHEAS). Evening (5 pm) blood samples were also taken for the evaluation of plasma cortisol level\u0000\u0000\u0000RESULTS\u0000There were no differences in mean age, body mass index (BMI), FSH, SHBG, PRL, estradiol and TSH levels between group A and group B. Mean plasma LH level was higher in group A compared to group B (10.7 ± 6.8 IU/l vs 6.6 ± 4.5 LU/l, p < 0.02). Mean plasma testosterone and DHEAS levels were also higher in PCOS patients (3.8 ± 0.6 nmol/l vs 1.63 ± 0.6 nmol/l; 427.7 ± 162.9 vs 236.6 ± 97.8 respectively, p < 0.001). Mean evening plasma cortisol level was higher in PCOS patients (11.8 ± 4.1 ug/dl vs 4.7 ± 1.3 ug/dl, p < 0.02). Mean morning plasma cortisol levels did not differ between groups.\u0000\u0000\u0000CONCLUSION\u0000PCOS women showed the increased evening plasma cortisol level with impacted diurnal secretion rate.","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83041778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Impact of body weight on clinical symptoms and endoscopic changes in patients with gastroesophageal reflux disease. 体重对胃食管反流病患者临床症状及内镜改变的影响
Pub Date : 2016-01-01
Malgorzata Krakowska-Stasiak, Dorota Cibor, Kinga Sałapa, Danuta Owczarek, Tomasz Mach

Introduction: Gastroesophagealreflux disease (GERD) is connectedwith body mass index (BMI) accordingto some recent studies. However, thelink between overweight and severityof GERD symptoms is still unclear.

Objectives: The aim of our studyis to assess the influence of BMI onclinical presentation and occurrenceof inflammatory changes in the esophagusin patients with GERD.

Material and methods: 121 clinicallydiagnosed GERD patients: 66 males(54.5%) and 55 females (45.5%), aged19 – 89 years were involved in thestudy. After the detailed anamnesisBMI was counted and gastroscopywas performed. All individuals whoagreed for upper endoscopy weredivided into three groups. 42 patients(34.7%) were classified as Non-ErosiveReflux Disease (NERD), 53 patients(43.8%) were diagnosed with ErosiveEsophagitis (EE), 11 patients (9.1%)with Barrett’s esophagus (BE). AmongEE group 34 patients were diagnosedwith grade A of esophagitis accordingto Los Angeles scale, 17 with grade B,2 with grade C and none with grade D.The differences between groups wereassessed using statistical analysis.

Results: The mean age of patientswas 50.2±12.9 years and the meanBMI was 25.5±4.2 kg/m2. Patients withBE were older (61.2±12.0 years) thanNERD (48.5±13.6 years); (p=0.028) andEE (50.4±11.4 years); (p=0.008). BE hadhigher BMI (27.0±4.4 kg/m2) as comparedto NERD (24.0±3.3 kg/m2); (p=0.022)and EE (24.4±3.1 kg/m2); (p=0.048). Hiatalhernia was more frequent in EE andBE (79.2% and 90.9%, respectively) ascompared to NERD (45.2%); (p<0.001).Patients EE and BE more frequentlycomplained to heartburn (84.9% and72.7%, respectively) than patients withno mucosal injury (42.9%); (p<0.001).Sleeping problems were encounteredby patients with higher levels of BMI.

Conclusion: This study demonstratesthat overweight predispose toesophageal inflammation and increasethe frequency of heartburn and sleepproblems in GERD patients.

最近的一些研究表明胃食管反流病(GERD)与身体质量指数(BMI)有关。然而,超重与反流症状严重程度之间的联系尚不清楚。目的:我们研究的目的是评估BMI对食管反流患者的临床表现和炎症改变发生的影响。材料与方法:121例临床诊断为胃食管反流的患者:男性66例(54.5%),女性55例(45.5%),年龄19 ~ 89岁。详细回忆后计算bmi并行胃镜检查。所有同意接受上颌内窥镜检查的人被分为三组。非糜烂性食管炎(NERD) 42例(34.7%),糜烂性食管炎(EE) 53例(43.8%),Barrett食管(BE) 11例(9.1%)。根据洛杉矶分级法,34例患者被诊断为A级食管炎,17例为B级,2例为C级,无患者被诊断为d级。组间比较采用统计学分析。结果:患者平均年龄为50.2±12.9岁,平均bmi为25.5±4.2 kg/m2。be患者年龄(61.2±12.0岁)大于annerd(48.5±13.6岁);(p=0.028), dee(50.4±11.4岁);(p = 0.008)。BE组BMI(27.0±4.4 kg/m2)高于NERD组(24.0±3.3 kg/m2);(p=0.022)和EE(24.4±3.1 kg/m2);(p = 0.048)。相比于NERD患者(45.2%),EE和be患者的裂孔疝发生率更高(分别为79.2%和90.9%);结论:本研究表明,超重易导致食管炎症,并增加胃食管反流患者发生胃灼热和睡眠问题的频率。
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引用次数: 0
[Microbiological diagnostics of infective endocarditis in the light of the new guidelines of the European Society of Cardiology with particular focus on the molecular methods]. [根据欧洲心脏病学会新指南,感染性心内膜炎的微生物诊断,特别关注分子方法]。
Pub Date : 2016-01-01
Malgorzata Małek-Elikowska, Waldemar Elikowski, Monika Lisiecka, Andrzej Szyszka

The authors describe the presentdaypossibilities of routine and molecularmicrobiologic diagnostics ofinfective endocarditis (IE). Routinediagnostics employs automated microbialgrowth and biochemical detectionsystems. Molecular methods are basedon polymerase chain reaction (PCR)and matrix assisted laser desorption/ionization time of flight mass spectrometry(MALDI-TOF MS). MALDI-TOFMS first appeared in the new guidelinesfor the management of IE of the EuropeanSociety of Cardiology publishedin 2015. The greatest benefit of MALDITOFMS is the short time of pathogenidentification. The main disadvantagesare the necessity of routine agar culturesand lack of antimicrobial susceptibilityestimation. So far, therehas been no Polish literature reporton MALDI-TOF MS used for pathogenidentification in suspected IE. This maywell result from scarce accessibility ofthe method in Poland. The paper aimsto stress the importance of an up-todatetechnology in the diagnostics ofdifficult, blood culture negative casesof IE. It also takes into considerationthe limitations of mass spectrometryin the ESC diagnostic scheme of IE.

作者描述了目前常规和分子微生物诊断有效心内膜炎(IE)的可能性。常规诊断采用自动化微生物生长和生化检测系统。分子方法是基于聚合酶链反应(PCR)和基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF MS)。MALDI-TOFMS首次出现在2015年发布的欧洲心脏病学会IE管理新指南中。MALDITOFMS最大的优点是病原鉴定时间短。其主要缺点是需要常规琼脂培养和缺乏抗菌药物敏感性评估。到目前为止,波兰尚未见MALDI-TOF MS用于疑似IE病原菌鉴定的文献报道。这很可能是由于波兰缺乏这种方法的可及性。本文旨在强调一项最新技术在诊断困难的、血培养阴性的IE病例中的重要性。同时也考虑到了质谱法在ESC诊断方案中的局限性。
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引用次数: 0
[Granulomatous lymphocytic interstitial lung disease (GLILD) as a manifestation of pulmonary changes in common variable immunodeficiency (CVID) – case report]. [肉芽肿性淋巴细胞间质性肺疾病(GLILD)作为常见变异性免疫缺陷(CVID)肺部改变的表现-病例报告]。
Pub Date : 2016-01-01
Elżbieta Marciszewska, Anna Szaflarska, Anna Pituch-Noworolska

Common variable immunodeficiency(CVID) comprise different kinds ofprimary hypogammaglobulinemias ofmostly unknown etiology. The onset ofthe disease and its clinical symptomsmay appear as well in children as inadults. Apart from susceptibility tobacterial, viral and fungal infections,other clinical signs (autoimmunization,non-infectious lung and gastrointestinaldiseases, neoplasm) are frequentlyobserved. About 58% of patients withCVID develops granulomatous andlymphocytic interstitial lung disease(GLILD) associated with early mortality.

常见变异性免疫缺陷(CVID)包括不同种类的原发性低γ -球蛋白血症,大多病因不明。该疾病的发病及其临床症状可在儿童和成人中出现。除了对细菌、病毒和真菌感染的易感性外,还经常观察到其他临床症状(自身免疫、非感染性肺和胃肠道疾病、肿瘤)。约58%的cvid患者发展为肉芽肿性和淋巴细胞间质性肺疾病(GLILD),与早期死亡相关。
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引用次数: 0
[Urinary tract infections in adults]. [成人尿路感染]。
Pub Date : 2016-01-01
Mikolaj Michno, Antoni Sydor

Review of urinary tract infectionsin adults including etiology, pathogenesis,classification and the mostimportant therapeutic recommendations.Urinary tract infections are stilla common clinical problem occurringmore often in sexually active women,pregnancy, elderly , after catherizationof a urinary bladder and urologicalsurgery as well as in the co-existenceof diabetes or nephrolithiasis. Due tothe anatomical differences, womensuffer more often than men. The mainetiological factor is Escherichia coli,even though it plays a lesser role inthe complicated infections, than innon-complicated ones. Apart from that,the infections may also be caused byatypical microbes, viruses and fungi.Relapses as well as reinfections aretypical features of urinary tract infectionsand in some cases prolongedinfections can spread from lower toupper urinary tract contributing topyelonephritis, urosepsis or evendeath. These long-term infections canprogress in a hidden, insidious, oligosymptomaticor asymptomatic mannerleading to irreversible, progressivedeterioration of renal function. Theycan also mask other diseases suchas tuberculosis or neoplasms ofthe urinary tract, which leads to thedelayed diagnosis and treatment.Diagnosis and treatment of urinarytract infections is a complex problem,often requiring specialized proceduresas well as hospitalization. The choiceof a therapy is determined by the typeof infection, general condition, ageand coexisting diseases. Rapid diagnosisand implementation of properpharmacotherapy may shorten thetime of treatment and hospitalization,preventing serious complications andreinfections.

综述成人尿路感染的病因、发病机制、分类和最重要的治疗建议。尿路感染仍然是常见的临床问题,多发生于性活跃的妇女、孕妇、老年人、膀胱导尿术和泌尿外科手术后以及糖尿病或肾结石患者。由于解剖学上的差异,女性比男性更容易遭受痛苦。主要的致病因素是大肠杆菌,尽管它在复杂感染中的作用小于非复杂感染。除此之外,感染还可能由非典型微生物、病毒和真菌引起。复发和再感染是尿路感染的典型特征,在某些情况下,长期感染可从下尿路扩散,导致脊髓肾炎、尿脓毒症甚至死亡。这些长期感染可能以隐蔽、隐匿、无症状或无症状的方式发展,导致肾功能不可逆转的进行性恶化。它们还可以掩盖其他疾病,如肺结核或泌尿道肿瘤,这导致延误诊断和治疗。尿路感染的诊断和治疗是一个复杂的问题,往往需要专门的程序和住院治疗。治疗的选择取决于感染的类型、一般情况、年龄和共存的疾病。快速诊断和适当药物治疗的实施可以缩短治疗和住院时间,防止严重并发症和感染。
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引用次数: 0
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Przeglad lekarski
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