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Effect of Swimming Exercise on Levels of Blood Glucose, Adiponectin, Glucose-6-Phosphatase and Lipid Profile in Diabetic Wistar Rats 游泳运动对糖尿病 Wistar 大鼠血糖、脂肪连接蛋白、葡萄糖-6-磷酸酶和血脂水平的影响
Pub Date : 2024-07-23 DOI: 10.11648/j.aap.20240901.12
Isehunwa Olufunmilayo, Layonu Mojirade
Diabetes mellitus is a chronic metabolic condition that causes persistent hyperglycemia due to insulin action or secretion. Regular physical exercise has been reported to improve glycemia and lipid profile in diabetes. However, literature is scare on the effects of swimming exercise on the serum levels of adiponectin and glucose 6 phosphatase in Wister rats with diabetes This study therefore, investigated the effects of swimming exercise on adiponectin, glucose 6-phosphatase and lipid profile in male Wistar rats with streptozotocin-induced diabetes. This study was carried out on 25 male Wistar rats grouped into five groups (n=5/group): group 1=control, group 2=diabetes, group 3=diabetes treated with metformin, group 4=non-diabetes and swimming exercise, group 5=diabetes and swimming exercise. Animals in groups 2, 3, and 5 were induced with Streptozotocin (STZ) 50 mg/kg intraperitoneally. After 72 hours of diabetes induction, animals with a blood glucose level of ≥ 200 mg/dl were confirmed diabetics and used for the study. Group 3 animals were treated with metformin 200mg/kg giving orally for 28 days. Animals in groups 4 and 5 were subjected to swimming exercises for 5-10 minutes during the first week until they could swim freely for 30 minutes. The animals were then allowed to swim 5 days per week for 28 days. Swimming exercise for 28 days significantly reduced blood glucose, glucose-6-phosphatase (G6Ppase), Lactate dehydrogenase (LDH), Total cholesterol (TC), and Low-density lipoprotein (LDL) levels but caused significant increase in adiponectin and High-density lipoprotein (HDL) levels in diabetic rats compared with untreated diabetic rats. There was a significant decrease in triglyceride (TG) of diabetic animals caused by swimming for 28 days. This study demonstrated that swimming exercise for 28 days may help lower glucose level and improve insulin sensitivity by increasing adiponectin level and decreasing G6Pase activity in diabetic rats. Also, swimming exercise may help improve lipid profile in diabetic rats.
糖尿病是一种慢性代谢疾病,由于胰岛素的作用或分泌而导致持续性高血糖。据报道,经常进行体育锻炼可改善糖尿病患者的血糖和血脂状况。然而,有关游泳运动对糖尿病 Wistar 雄性大鼠血清中脂联素及葡萄糖 6-磷酸酶水平影响的文献却很少。这项研究以 25 只雄性 Wistar 大鼠为对象,分为五组(n=5/组):第 1 组=对照组,第 2 组=糖尿病组,第 3 组=二甲双胍治疗糖尿病组,第 4 组=非糖尿病和游泳运动组,第 5 组=糖尿病和游泳运动组。第 2、3 和 5 组的动物腹腔注射链脲佐菌素(STZ)50 毫克/千克。糖尿病诱导 72 小时后,血糖水平≥ 200 mg/dl 的动物被确认为糖尿病患者并用于研究。第 3 组动物连续 28 天口服二甲双胍 200 毫克/千克。第 4 组和第 5 组动物在第一周接受 5-10 分钟的游泳训练,直到它们可以自由游泳 30 分钟。然后让动物每周游泳 5 天,共 28 天。与未经治疗的糖尿病大鼠相比,连续 28 天的游泳运动能显著降低糖尿病大鼠的血糖、葡萄糖-6-磷酸酶(G6Ppase)、乳酸脱氢酶(LDH)、总胆固醇(TC)和低密度脂蛋白(LDL)水平,但能显著增加脂肪连通素和高密度脂蛋白(HDL)水平。游泳 28 天后,糖尿病动物的甘油三酯(TG)明显下降。这项研究表明,持续 28 天的游泳运动可通过提高糖尿病大鼠的脂肪连接蛋白水平和降低 G6Pase 活性,帮助降低血糖水平和改善胰岛素敏感性。此外,游泳运动还有助于改善糖尿病大鼠的血脂状况。
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引用次数: 0
Impact of Somatic Cell Count on Milk Yield, Milk Composition, and Growth Performance in Zaraibi Goats During Different Physiological Stages of Lactation Period 泌乳期不同生理阶段体细胞计数对宰来壁山羊产奶量、乳成分及生长性能的影响
Pub Date : 2023-08-17 DOI: 10.11648/j.aap.20230802.11
Ahmed Abdelrazek Gabr, Mohamed Ahmed Ibrahim Ahmed, Rasha Abdalla Hawas
: The study investigated the effect of different somatic cell count (SCC) classes on milk production traits and growth of Zaraibi does and kids at three distinct physiological stages during lactation. A total of 150 milk samples obtained from 50 goats at milk peak, kids weaning, and meeting periods (days of 50, 100 and 150) were analyzed. The goats were selected based on strict criteria, including the same age, kidding date, low milk SCC, and no udder problems. The goats were divided into three classes based on overall milk SCC values: SCG1 (≤315x10 3 cells/mL), SCG2 (316-335x10 3 cells/mL), and SCG3 (>335 x10 3 cells/mL). The results showed that although there were significant differences between SCC1 and SCC2 classes in SCC and log SCC at different stages of lactation, there were no significant differences in milk production and composition. The daily milk yield decreased significantly with increased SCC level (> 335x10 3 cells/mL), and the highest milk losses were observed. The milk composition followed the same pattern of significant differences among SCC classes during different lactation stages, with the highest values observed in the highest SCC class (> 335x10 3 cells/mL). The daily milk yield decreased gradually with increasing lactation stage, while SCC values increased gradually. The does’ body weight did not change significantly by lactation stage. Overall, the findings suggest that SCC level of > 335x10 3 cells/mL has a significant effect on milk production and composition, but not on growth traits of Zaraibi does’ and kids during different stages of lactation. These findings could be useful for dairy farmers to manage their herds and optimize milk production to produce high-quality dairy products.
研究了不同体细胞计数(SCC)等级对泌乳期三个不同生理阶段宰来比公羊和雏鸡产乳性状和生长发育的影响。分析了50只山羊在泌乳高峰、断奶期和会期(50、100和150天)采集的150份奶样。山羊是根据严格的标准选择的,包括相同的年龄,开玩笑的日期,低奶SCC,没有乳房问题。根据羊奶SCC值将山羊分为SCG1(≤315x10 3 cells/mL)、SCG2 (316-335x10 3 cells/mL)和SCG3 (>335 x10 3 cells/mL) 3个等级。结果表明,虽然SCC1类和SCC2类在泌乳不同阶段的SCC和log SCC存在显著差异,但产奶量和成分差异不显著。随着SCC水平的升高,日产奶量显著降低(> 335x10 3细胞/mL),泌乳损失最大。乳成分在不同哺乳期的SCC类别之间也存在显著差异,最高SCC类别的乳成分最高(> 335x10 3个细胞/mL)。随着泌乳期的延长,日产奶量逐渐降低,SCC值逐渐升高。泌乳期母猪体重变化不显著。综上所述,SCC水平> 335x10 3个细胞/mL对泌乳不同阶段宰来比和幼鹿的产奶量和乳成分有显著影响,但对其生长性状无显著影响。这些发现可能有助于奶农管理他们的牛群和优化牛奶产量,以生产高质量的乳制品。
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引用次数: 0
Effects of Sex and Weight on Fasting Blood Glucose in Mice Mus musculus, and Rats Rattus norvegicus 性别和体重对小鼠和大鼠空腹血糖的影响
Pub Date : 2023-06-10 DOI: 10.11648/j.aap.20230801.15
Isehunwa Grace Olufunmilayo, S. Sheu-Tijani, Apeji Comfort Oiza, Ayedun Mojisola Temidayo
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引用次数: 0
The Correlation of Anthropometric, the Estradiol Level and Obesity in Perimenopausal and Menopausal Saudi Women 围绝经期和绝经期沙特妇女的人体测量、雌二醇水平与肥胖的相关性
Pub Date : 2023-05-17 DOI: 10.11648/j.aap.20230801.13
Lina Mohammed Alneghery
: In this study we assess the age-specific variation anthropometric measurements, the estradiol hormone, and Body Mass Index variation levels among perimenopausal and menopausal Saudi women. We conducted this study on 41 healthy women aged 40 to 75 and divided them into two groups. The group included 25 perimenopausal women (<50 Years), and 16 menopausal women (>50 Years) were examined. Demographic data were recorded
在这项研究中,我们评估了围绝经期和绝经期沙特妇女的年龄特异性变化,人体测量、雌二醇激素和体重指数变化水平。我们对41名40至75岁的健康女性进行了这项研究,并将她们分为两组。本组包括25名围绝经期妇女(50岁)。记录了人口统计数据
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引用次数: 0
Antiulcer Effect of an Aqueous Extract of Syzygium aromaticum (Myrtaceae) Buds in Wistar Rats 金合欢芽水提物对Wistar大鼠的抗溃疡作用
Pub Date : 2023-05-17 DOI: 10.11648/j.aap.20230801.14
Irié Bi Jean Sévérin, Kahou Bi Gohi Parfait, N’Doua Akouah Leatitia Rosemonde, Lehou Monnhéssea Flore Danielle, Zahoui Ouga Stanistlas, Abo Kouakou Jean-Claude
Antiulcer Effect of an Aqueous Extract of Syzygium aromaticum (
香薷水提物的抗溃疡作用(
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引用次数: 0
Dietary Chitosan Supplementation Modulates Hematology, Lipid Profile, Rumen Function, Antioxidant Status, and Thyroxin in Zaraibi Goat Bucks Fed on High-Fat Diets 日粮中添加壳聚糖对高脂饲粮宰来比山羊血液学、血脂、瘤胃功能、抗氧化状态和甲状腺素的调节作用
Pub Date : 2023-03-03 DOI: 10.11648/j.aap.20230801.12
Doaa H. Assar, Z. Elbialy, R. A. Al wakeel, N. Gomaa, Mahmoud Metwaly El-Maghraby, Wael Mohamed Nagy, Adel Abd El Aziz El-badawy, Abdel-Khalek El-Sayed Abdel-Khalek
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引用次数: 0
Physical Activity, Physical Function and Neighborhood Environment Adaptation Among Older Adults Dwelling in Asaba, Delta State, Nigeria 尼日利亚三角洲州阿萨巴老年人的身体活动、身体功能和社区环境适应
Pub Date : 2023-01-09 DOI: 10.11648/j.aap.20230801.11
Ogbutor Udoji Godsday, Olisa Chisom Kingsley, Ephraim Chukwuemeka, Kizito Bright, Ezunu Emmanuel, Nworah Awele Maria, Nwangwa Eze Kingsley
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引用次数: 0
Verification of Comet Plus 475 G/L EC Fungicide Against Wheat Stripe Rust (Puccinia striiformis f.sp. tritici) Disease on Bread Wheat in Bale, Southeastern Ethiopia Comet Plus 475 G/L EC杀菌剂对小麦条锈病的防治效果验证埃塞俄比亚东南部贝尔面包小麦的小麦黑穗病
Pub Date : 2021-10-12 DOI: 10.11648/J.AAP.20210602.11
T. Mideksa, Zerihun Eshetu
Wheat (Triticum aestivum L.) is the most widely cultivated crops in Ethiopia. However, wheat production is very low due to many factors. Of these, disease like stripe rust of wheat is the main constrained biotic factor and cause great yield losses. The field experiment was conducted at three hot-spot locations of wheat rust diseases in the zone namely; Sinana, Selka, and Agarfa during the 2019 cropping season to evaluate the effectiveness of newly introduced fungicide for the management of yellow rust disease of wheat. Variety Kubsa, which is susceptible to the three wheat rusts were used. The trial was laid out at three locations with non-replicated plots. Two systemic fungicides (Comet plus and Rex®Duo) and untreated plot (control) were used as a treatment. A significant difference (P<0.05) was observed between fungicide treatments and unsprayed plots on yellow rust severity, grain yield, thousand kernel weight, and hectoliter. Based on field observation and analyzed data results revealed that the newly introduced fungicide found to be effective in controlling stripe rust of wheat. Thus, Comet plus 475 G/L EC is recommended as an alternative fungicide for the management of stripe rust of wheat in wheat-growing areas of the country.
小麦(Triticum aestivum L.)是埃塞俄比亚种植最广泛的作物。然而,由于多种因素的影响,小麦产量非常低。其中,小麦条锈病等病害是制约小麦产量的主要生物因素,造成了较大的产量损失。田间试验在该地区三个小麦锈病高发区分别进行;在2019年种植季期间,对Sinana、Selka和Agarfa进行试验,以评估新引进的杀菌剂对小麦黄锈病管理的有效性。选用对三种锈病敏感的小麦品种库布沙。试验在三个地点进行,没有重复的情节。两种系统杀菌剂(Comet plus和Rex®Duo)和未经处理的地块(对照)作为处理。在黄锈病严重程度、产量、千粒重、百升等指标上,杀菌剂处理与未喷施区差异显著(P<0.05)。通过田间观察和资料分析,发现新引进的杀菌剂对小麦条锈病有较好的防治效果。因此,Comet加475 G/L EC被推荐作为该国小麦种植区小麦条锈病管理的替代杀菌剂。
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引用次数: 0
Effectiveness of Imazapyr Coated Hybrids and Selected Striga-tolerant Varieties on S. hermonthica Management and Maize Yield Performance in Western Part of Kenya 依马唑吡包衣杂交种和抗曲菌病选种对肯尼亚西部稻月曲菌管理和玉米产量的影响
Pub Date : 2021-03-12 DOI: 10.11648/J.AAP.20210601.11
Sibuti Mwita Samwel, K. Paul, O. Joshua
Striga hermonthica, an obligate root hemi-parasite, is a massive biological constraint that hinders maize (Zea mays L.) production in western part of Kenya particularly when susceptible varieties are used. Use of Imazapyr resistant hybrids coated with small doses of imazapyr herbicide offers potential for management of Striga hermonthica and increase maize production. A study was conducted to evaluate the effectiveness of Imazapyr Resistant Maize (IRM) and selected striga tolerant varieties on S. hermonthica management and yield of maize. Field trials were conducted during two successive cropping seasons (2018 and 2019) at Alupe Research Station (artificial inoculation), farmer’s field in Rangwe (natural infestation) and Koibatek Agricultural Training College (striga free) in Busia, Homa Bay and Baringo Counties respectively. The genotypes were evaluated in randomized complete block design with three replication. Test materials comprised of two IRM (H528IR, FRC425IR), two striga tolerant (KSTP94, GAF4), five susceptible commercial hybrids (DK8031, H513, DUMA43, DH04, Haraka 101) and two local landraces (Shipindi, Nya Uyoma). All striga and crop data collected were subjected to analysis of variance and means separated using Tukey’s HSD test. Results showed that IRM varieties significantly (P≤0.05) reduced number of emerged striga plants by 56 and 69% compared to the local landraces and commercial hybrids, respectively. Similarly, IRM varieties produced 50.3 and 79.5% higher grain yields compared to striga tolerant (KSTP94 and GAF 4) and susceptible hybrids, respectively under striga infestation. However, the grain yields recorded at Koibatek ATC (striga free) were 67 and 70% higher than at the Rangwe and Alupe sites, respectively. These findings show that use of Imazapyr resistant technology in maize production contributes to improved striga management and enhances maize grain yields. This technology can be integrated with other measures to contain striga in infested areas.
稻月Striga是一种专性根半寄生虫,是肯尼亚西部玉米(Zea mays L.)生产的巨大生物制约因素,特别是在使用易感品种时。使用涂有小剂量伊马唑吡尔除草剂的抗伊马唑吡尔杂交种,为管理稻月曲菌和提高玉米产量提供了潜力。本研究评价了抗Imazapyr玉米(IRM)和选定的耐思特里加玉米品种对稻月曲菌管理和玉米产量的影响。田间试验于2018年和2019年连续两个种植季分别在布希亚县、霍马湾县和巴林戈县的Alupe研究站(人工接种)、Rangwe农民田间(自然侵染)和Koibatek农业培训学院(无striga)进行。采用3个重复的随机完全区组设计评估基因型。试验材料包括两个IRM (H528IR, FRC425IR),两个耐striga (KSTP94, GAF4),五个敏感的商业杂交(DK8031, H513, DUMA43, DH04, Haraka 101)和两个地方品种(Shipindi, Nya Uyoma)。收集到的所有striga和crop数据均采用Tukey’s HSD检验进行方差分析和均值分离。结果表明,IRM品种与地方杂交种和商业杂交种相比,分别显著(P≤0.05)减少了56%和69%的反曲体植株出苗数量。同样,IRM品种在stristria侵染下的粮食产量比耐stristria品种(KSTP94和gaf4)和敏感品种分别高出50.3%和79.5%。然而,Koibatek ATC(无striga)记录的粮食产量分别比Rangwe和Alupe站点高67%和70%。这些研究结果表明,在玉米生产中使用抗Imazapyr技术有助于改善曲菌病管理,提高玉米产量。该技术可与其他措施相结合,在疫区遏制斯特里格原虫。
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引用次数: 2
An Approach Study for Reducing the Early Embryonic Loss in Egyptian Buffalo-cows 减少埃及水牛早期胚胎损失的方法研究
Pub Date : 2020-11-30 DOI: 10.11648/j.aap.20200502.17
M. Abo-Farw, O. Elmalky, Emad Fawzy Elmaghraby, Hassab Allah Abdul Gwad Abu Elghait, M. Aboul-Omran
This study evaluated the efficacy of a single gonadotropin-releasing hormone (GnRH) agonist on day 12 or human chorionic gonadotropin (hCG) on day 7 post-mating on pregnancy rate (PR) of repeat breeder buffaloes. Buffaloes (n=21) in heat were naturally mated, and divided into three groups (7 in each). Animals in the 1st group (G1) were i.m. injected with 5 ml GnRH on 12-day post-mating, while those in G2 were i.m. injected with 1500 IU of hCG on day 7 post-mating. In G3, animals were kept as control. Results show that PR was higher (P<0.05) in G1 (71.428) and G2 (57.142) than G3 (28.571). The peak of serum P4 was recorded (P<0.05) on day 15 in G2, and day 18 in G1 and G3. On days 21 and 24 post-mating, P4 was the highest (P<0.05) in G1, followed by G2, and the lowest in G3. Average CL diameter increased (P<0.05) CL in G1and G2 compared with G3 on days 15 and 18 post-mating. The concentration of P4 was higher in pregnant than in non-pregnant animals on different post-mating days, regardless of treatment. The concentration of P4 was the highest in pregnant of G2, and the lowest in non-pregnants of G3, being more obvious from 18 to 24-day post-mating. Injection of repeat breeder lactating buffaloes with 5 ml GnRH or 1500 IU hCG on day 12 and 7 post-mating, respectively, improved P4 production and pregnancy rate. GnRH treatment reduced the early embryonic loss showing the highest pregnancy rate to increase the farmer economy.
本研究评估了在交配后第 12 天使用单次促性腺激素释放激素(GnRH)激动剂或第 7 天使用人绒毛膜促性腺激素(hCG)对重复配种水牛妊娠率(PR)的影响。发情水牛(21 头)自然交配后分为三组(每组 7 头)。第一组(G1)的动物在交配后 12 天静注 5 毫升 GnRH,G2 的动物在交配后第 7 天静注 1500 IU hCG。G3 组动物作为对照组。结果显示,G1(71.428)和G2(57.142)的PR高于G3(28.571)(P<0.05)。G2 的血清 P4 在第 15 天达到峰值(P<0.05),G1 和 G3 则在第 18 天达到峰值(P<0.05)。交配后第 21 和 24 天,G1 的 P4 最高(P<0.05),G2 次之,G3 最低。交配后第 15 和 18 天,G1 和 G2 的 CL 平均直径比 G3 增加(P<0.05)。在交配后的不同天数,无论采用何种处理,妊娠动物的 P4 浓度均高于非妊娠动物。G2妊娠动物的P4浓度最高,G3非妊娠动物的P4浓度最低,这在交配后18至24天更为明显。分别在交配后第 12 天和第 7 天对重复繁殖的哺乳水牛注射 5 毫升 GnRH 或 1500 IU hCG,可提高 P4 的产生量和妊娠率。GnRH 治疗减少了早期胚胎损失,显示出最高的妊娠率,从而提高了农民的经济效益。
{"title":"An Approach Study for Reducing the Early Embryonic Loss in Egyptian Buffalo-cows","authors":"M. Abo-Farw, O. Elmalky, Emad Fawzy Elmaghraby, Hassab Allah Abdul Gwad Abu Elghait, M. Aboul-Omran","doi":"10.11648/j.aap.20200502.17","DOIUrl":"https://doi.org/10.11648/j.aap.20200502.17","url":null,"abstract":"This study evaluated the efficacy of a single gonadotropin-releasing hormone (GnRH) agonist on day 12 or human chorionic gonadotropin (hCG) on day 7 post-mating on pregnancy rate (PR) of repeat breeder buffaloes. Buffaloes (n=21) in heat were naturally mated, and divided into three groups (7 in each). Animals in the 1st group (G1) were i.m. injected with 5 ml GnRH on 12-day post-mating, while those in G2 were i.m. injected with 1500 IU of hCG on day 7 post-mating. In G3, animals were kept as control. Results show that PR was higher (P<0.05) in G1 (71.428) and G2 (57.142) than G3 (28.571). The peak of serum P4 was recorded (P<0.05) on day 15 in G2, and day 18 in G1 and G3. On days 21 and 24 post-mating, P4 was the highest (P<0.05) in G1, followed by G2, and the lowest in G3. Average CL diameter increased (P<0.05) CL in G1and G2 compared with G3 on days 15 and 18 post-mating. The concentration of P4 was higher in pregnant than in non-pregnant animals on different post-mating days, regardless of treatment. The concentration of P4 was the highest in pregnant of G2, and the lowest in non-pregnants of G3, being more obvious from 18 to 24-day post-mating. Injection of repeat breeder lactating buffaloes with 5 ml GnRH or 1500 IU hCG on day 12 and 7 post-mating, respectively, improved P4 production and pregnancy rate. GnRH treatment reduced the early embryonic loss showing the highest pregnancy rate to increase the farmer economy.","PeriodicalId":211651,"journal":{"name":"Advances in Applied Physiology","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127906936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Advances in Applied Physiology
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