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Effects of pay for performance in primary care in an under-registration scenario. 在注册不足的情况下,按绩效付酬对初级保健的影响。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-18 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2024058005812
Paula de Castro-Nunes, Paloma Palmieri, Hugo Bellas, Adriana Soares, Jaqueline Viana, Paulo Victor Rodrigues de Carvalho, Alessandro Jatobá

Objective: To propose a method for detecting and analyzing under-registration and highlight its potential financial effect in view of the implementation of the Previne Brasil Program.

Methods: An ecological study was carried out to analyze cytopathological exams in programmatic area 3.1 in the municipality of Rio de Janeiro. The data was collected from the Departamento de Informática do Sistema Único de Saúde (DATASUS - Department of Informatics of the Unified Health System) database, including information on reports from outsourced cytopathology laboratories and those available in the Sistema de Informação em Saúde para a Atenção Básica (SISAB - Health Information System for Primary Care) and the Sistema de Informação do Câncer do Colo do Útero (SISCOLO - Cervical Cancer Information System) of DATASUS/Ministry of Health.

Results: The estimated under-registrations per health unit totaled 108,511 exams in the last two years in the programmatic area 3.1 area, which corresponds to an estimated total of R$ 435,129.00 that would have been foregone if the Previne Brasil Program had been in place during the period studied.

Conclusion: The article's main contribution lies in the presentation of empirical evidence of the potential effects of under-registration on Primary Health Care financing. In addition, there are two other significant findings - firstly, it highlights weaknesses in the process of recording health information inherent to vulnerable regions; secondly, it indicates a vicious circle potentially fueled by sudden changes in Primary Health Care funding conditions, in addition to potential consequences for other levels of care.

目的提出一种检测和分析登记不足的方法,并强调其对实施巴西普雷韦恩计划的潜在经济影响:我们开展了一项生态研究,对里约热内卢市 3.1 计划区的细胞病理学检查进行分析。数据收集自Departamento de Informática do Sistema Único de Saúde (DATASUS - 统一卫生系统信息部)数据库、其中包括外包细胞病理学实验室的报告信息,以及 DATASUS/卫生部的 Sistema de Informação em Saúde para a Atenção Básica (SISAB - 初级医疗保健信息系统) 和 Sistema de Informação do Câncer do Colo do Útero (SISCOLO - 宫颈癌信息系统) 中的报告信息。结果:据估计,在过去两年中,在 3.1 计划领域,每个医疗单位少登记的检查总数为 108,511 例,这相当于如果在研究期间实施巴西普瑞万计划,估计会少收 435,129.00 雷亚尔:本文的主要贡献在于提供了经验证据,证明登记不足对初级保健筹资的潜在影响。此外,文章还得出了另外两个重要结论:首先,文章强调了脆弱地区在记录卫生信息过程中固有的弱点;其次,文章指出了初级卫生保健筹资条件的突然变化可能造成的恶性循环,以及对其他各级保健的潜在影响。
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引用次数: 0
Access to primary healthcare services among adults with disabilities in Brazil. 巴西成年残疾人获得初级医疗保健服务的情况。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-18 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2024058005842
Veronika Reichenberger, Maria Eduarda Lima de Carvalho, Tom Shakespeare, Shaffa Hameed, Tereza Maciel Lyra, Maria do Socorro Velo de Albuquerque, Loveday Penn-Kekana, Christina May Moran de Brito, Luciana Sepúlveda Köptcke, Hannah Kuper

Objective: To investigate perspectives of people with disabilities in Brazil regarding the access to primary healthcare.

Methods: In-depth interviews were conducted with 44 individuals with disabilities in Pernambuco, Distrito Federal, and São Paulo between March 2020 and November 2021. These interviews were transcribed, coded, and analysed thematically, using the Levesque framework to identify healthcare access barriers.

Results: Participants expressed a solid understanding of their healthcare needs and existing obstacles. However, individuals with hearing and visual impairments experience challenges because of communication barriers. In Pernambuco, the Community Health Agent was often the initial point of contact for primary care services. Public transportation lacked accessibility, from buses to driver attitudes, posing difficulties for people with disabilities. More accessible transportation and improved urban infrastructure could enhance service access. High medication costs were reported due to limited healthcare unit availability. Communication accessibility issues, inadequate audio-visual resources and equipment were also identified as barriers. Attitudinal barriers among healthcare professionals and subpar home visit services further hinder access.

Conclusion: To address these challenges and improve the well-being of individuals with disabilities in Brazil, comprehensive action is essential. This includes leadership, governance, and resource allocation reforms to meet healthcare needs. Initiatives like disability-focused training for service providers, enhanced transportation options, improved information accessibility, and increased support from community healthcare workers can collectively enhance the lives of people with disabilities.

目的调查巴西残疾人对获得初级医疗保健服务的看法:在 2020 年 3 月至 2021 年 11 月期间,对伯南布哥州、联邦区和圣保罗的 44 名残疾人进行了深入访谈。对这些访谈进行了誊写、编码和主题分析,并使用 Levesque 框架来识别医疗服务获取障碍:结果:受访者对自己的医疗需求和现有障碍表示了充分的了解。然而,有听力和视力障碍的人由于沟通障碍而面临挑战。在伯南布哥州,社区卫生代理通常是初级保健服务的第一联系人。公共交通缺乏无障碍设施,从公共汽车到司机的态度,都给残疾人带来了困难。更无障碍的交通和更好的城市基础设施可以提高服务的可及性。据报告,由于医疗单位有限,药物费用很高。沟通无障碍问题、视听资源和设备不足也被认为是障碍。医疗保健专业人员的态度障碍和不完善的家访服务进一步阻碍了服务的获取:要应对这些挑战并改善巴西残疾人的福祉,必须采取综合行动。这包括领导力、治理和资源分配改革,以满足医疗保健需求。为服务提供者提供以残疾问题为重点的培训、加强交通选择、改善信息无障碍以及增加社区医疗工作者的支持等举措,可以共同改善残疾人的生活。
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引用次数: 0
Early ultra-processed foods consumption and hyperactivity/inattention in adolescence. 过早食用超加工食品与青春期多动/注意力不集中。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-18 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2024058005636
Ricardo Campos Ferreira, Angela Helena Marin, Marcia Regina Vitolo, Paula Dal Bo Campagnolo

Objective: To investigate the relationship between childhood consumption of ultra-processed foods and symptoms of hyperactivity/inattention in adolescents from São Leopoldo, a city in southern Brazil.

Methods: Data were collected at four distinct stages: when participants were 12-16 months old in 2001 and 2002 and later when they were 3-4, 7-8, and 12-13 years old. During the interview at 12-16 months, mothers were asked about the introduction of sugar in their child's diet. Two 24-hour recall surveys were conducted with children aged 3-4, 7-8, and 12-13 years to assess their consumption of ultra-processed foods. At the age of 12-13 years, the participants completed the Hyperactivity/Inattention subscale of the Strengths and Difficulties Questionnaire (SDQ), which screens for mental health problems.

Results: Among the 173 adolescents, 22.5% exhibited hyperactivity symptoms. The consumption of ultra-processed foods in grams, kilocalories, and as a percentage of energy intake at 3-4 years old were found to be predictors of hyperactivity/inattention symptoms (RR: 0.81, 95%CI: 0.69-0.95; RR: 1.01, 95%CI: 1.00-1.02; RR: 1.02, 95%CI:1.01-1.02; RR: 1.25, 95%CI:1.04-1.51, respectively).

Conclusion: The consumption of ultra-processed foods at an early age was associated with hyperactivity and inattention symptoms in adolescence.

目的调查巴西南部城市圣里奥波尔多青少年童年时期食用超加工食品与多动/注意力不集中症状之间的关系:在四个不同阶段收集数据:2001 年和 2002 年参与者 12-16 个月大时,以及之后 3-4、7-8 和 12-13 岁时。在 12-16 个月大时进行的访谈中,母亲被问及在孩子的饮食中添加糖的情况。对 3-4、7-8 和 12-13 岁的儿童进行了两次 24 小时回忆调查,以评估他们食用超加工食品的情况。在 12-13 岁时,受试者完成了优势与困难问卷(SDQ)中的多动/注意力不集中分量表,该问卷用于筛查心理健康问题:在 173 名青少年中,22.5% 的人表现出多动症状。以克、千卡和占能量摄入百分比计算的3-4岁青少年超加工食品摄入量可预测多动/注意力不集中症状(RR:0.81,95%CI:0.69-0.95;RR:1.01,95%CI:1.00-1.02;RR:1.02,95%CI:1.01-1.02;RR:1.25,95%CI:1.04-1.51):结论:幼年时期食用超加工食品与青少年时期的多动和注意力不集中症状有关。
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引用次数: 0
Social representations of HIV and healthcare among recently diagnosed youth. 新近确诊的年轻人对艾滋病毒和医疗保健的社会表述。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2024058005594
Rosana Guarnieri, Fernanda Cangussu Botelho, Luís Augusto Vasconcelos da Silva, Eliana Miura Zucchi

Objective: To understand the social representations of HIV and their repercussions for the healthcare among recently diagnosed youth.

Methods: This qualitative research was conducted within PrEP15-19, a study that analyzed the effectiveness of HIV pre-exposure prophylaxis in adolescents aged 15 to 19 years. Semi-structured interviews were conducted with nine participants, of whom eight identified themselves as gay men and one as travesti. All were diagnosed with HIV as this study was conducted in São Paulo and Salvador from 2019 to 2020. The interview guide covered aspects of HIV prevention and repercussions on care. Data were thematically analyzed and interpreted based on social representations theory.

Results: Participants reported experiences of stigma and discrimination related to their sexual orientation and gender identity and expression. Their diagnosis renewed these painful experiences as it referred to the common-sense social representations of HIV and AIDS based on precarious knowledge of HIV prevention, treatment, and transmission. Analysis of facilitators and barriers to care strongly related treatment adherence to health services welcoming people with information, support, and careful listening. Barriers were related to health services' constraints, such as lack of privacy, professionals' hostility, and insecurity regarding diagnosis confidentiality.

Conclusions: The social representations of HIV are an important dimension of youths' experience receiving their diagnosis, especially since it renews stories of violence, homophobia, transphobia, stigma, and discrimination. Understanding this based on youths' narratives is an important tool to formulate public policies aimed at the needs of this age group. Therefore, building new social representations to mitigate stigma constitutes one of the most important elements to face the HIV epidemic among adolescents and youth.

目的了解艾滋病的社会表征及其对新近确诊青少年医疗保健的影响:这项定性研究是在 PrEP15-19 中进行的,该研究分析了 HIV 暴露前预防措施在 15 至 19 岁青少年中的有效性。研究人员对九名参与者进行了半结构化访谈,其中八人自称为男同性恋者,一人自称为男同性恋者。由于本研究于 2019 年至 2020 年在圣保罗和萨尔瓦多进行,因此所有参与者均已确诊感染艾滋病毒。访谈指南涵盖了艾滋病毒预防和护理影响的各个方面。根据社会表征理论对数据进行了主题分析和解释:参与者报告了与他们的性取向、性别认同和性别表达有关的耻辱和歧视经历。他们的诊断结果再次重现了这些痛苦的经历,因为这涉及到基于对艾滋病毒预防、治疗和传播的不确定知识而对艾滋病毒和艾滋病的常识性社会表征。对治疗的促进因素和障碍的分析显示,坚持治疗与医疗服务机构提供的信息、支持和细心倾听密切相关。障碍则与医疗服务的限制因素有关,如缺乏隐私、专业人员的敌意以及对诊断保密的不安全感:艾滋病病毒的社会表征是青少年接受诊断经历的一个重要方面,尤其是因为它重新讲述了暴力、仇视同性恋、仇视变性者、羞辱和歧视的故事。根据青年的叙述来理解这一点,是针对这一年龄组的需求制定公共政策的重要工具。因此,建立新的社会表象以减轻耻辱感,是应对青少年艾滋病疫情的最重要因素之一。
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引用次数: 0
At the intersections: operationalizing intersectional thematic analysis in HIV prevention. 交叉点:在艾滋病毒预防中实施交叉主题分析。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2020054005728
Cristiane Spadacio, Lorruan Alves Dos Santos, Ramiro Andres Fernandez Unsain, Isa da Silva Sorrentino, Marcia Thereza Couto

Objective: This study aims to provide theoretical and methodological tools to assist in producing thematic analyses guided by an intersectional approach in empirically-based qualitative health studies. It argues that combining an intersectional perspective with thematic analysis can update the latter-which is quite popular in qualitative health investigations-regarding meaningful discussions about multiple and interconnected patterns of privilege and oppression that operate structurally and institutionally, producing experiences of relative disadvantage in individuals according to their gender, race/ethnicity, class, sexuality, generation, among other positions.

Methods: Based on an article that analyzed qualitative empirical data from a longitudinal demonstrative study on pre-exposure prophylaxis for HIV (PrEP) in adolescents and young people aged 15 to 19 years in two Brazilian capitals, this study discusses the limitations, challenges, and potentialities of the theoretical and methodological efforts undertaken by those authors. Additionally, this research that offers a proposal for operationalizing thematic analysis with intersectional sensitivity.

Results: It observed that triangulating techniques can enhance thematic analysis with intersectional sensitivity to produce qualitative data. Adopting an a priori intersectional proposal, starting from the research design phase, construction, and application of data production instruments with intersectional intentionality, enables the recognition of the relations between social markers in analytical categories.

Discussion: However, the absence of an intersectional theoretical-methodological perspective to conceive research and produce data fails to render intersectionality as a methodological tool unfeasible, although it may limit result analysis and discussion. Such limitations can be addressed by proposing intersectional assumptions and comparing the results with literature related to the theme and object of study.

研究目的本研究旨在提供理论和方法论工具,以帮助在基于经验的定性健康研究中以交叉方法为指导进行专题分析。本研究认为,将交叉视角与专题分析相结合可以更新后者--后者在定性健康调查中相当流行--关于特权和压迫的多重和相互关联模式的有意义的讨论,这些特权和压迫在结构性和制度性上运作,根据个人的性别、种族/民族、阶级、性取向、世代等立场,在个人中产生相对不利的体验:本研究以一篇文章为基础,分析了巴西两个城市 15 至 19 岁青少年艾滋病暴露前预防(PrEP)纵向示范研究的定性经验数据,讨论了作者在理论和方法上所做努力的局限性、挑战和潜力。此外,本研究还提出了具有交叉敏感性的专题分析操作建议:结果:研究发现,三角测量技术可以增强具有交叉敏感性的专题分析,从而产生定性数据。采用先验的交叉性建议,从研究设计阶段开始,构建和应用具有交叉意向性的数据生产工具,能够在分析类别中识别社会标记之间的关系:然而,缺乏交叉性理论-方法论视角来构思研究和编制数据,并不能使交叉性作为一种方法论工具变得不可行,尽管它可能会限制结果分析和讨论。可以通过提出交叉性假设,并将结果与与研究主题和对象相关的文献进行比较,来解决这种局限性。
{"title":"At the intersections: operationalizing intersectional thematic analysis in HIV prevention.","authors":"Cristiane Spadacio, Lorruan Alves Dos Santos, Ramiro Andres Fernandez Unsain, Isa da Silva Sorrentino, Marcia Thereza Couto","doi":"10.11606/s1518-8787.2020054005728","DOIUrl":"10.11606/s1518-8787.2020054005728","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to provide theoretical and methodological tools to assist in producing thematic analyses guided by an intersectional approach in empirically-based qualitative health studies. It argues that combining an intersectional perspective with thematic analysis can update the latter-which is quite popular in qualitative health investigations-regarding meaningful discussions about multiple and interconnected patterns of privilege and oppression that operate structurally and institutionally, producing experiences of relative disadvantage in individuals according to their gender, race/ethnicity, class, sexuality, generation, among other positions.</p><p><strong>Methods: </strong>Based on an article that analyzed qualitative empirical data from a longitudinal demonstrative study on pre-exposure prophylaxis for HIV (PrEP) in adolescents and young people aged 15 to 19 years in two Brazilian capitals, this study discusses the limitations, challenges, and potentialities of the theoretical and methodological efforts undertaken by those authors. Additionally, this research that offers a proposal for operationalizing thematic analysis with intersectional sensitivity.</p><p><strong>Results: </strong>It observed that triangulating techniques can enhance thematic analysis with intersectional sensitivity to produce qualitative data. Adopting an a priori intersectional proposal, starting from the research design phase, construction, and application of data production instruments with intersectional intentionality, enables the recognition of the relations between social markers in analytical categories.</p><p><strong>Discussion: </strong>However, the absence of an intersectional theoretical-methodological perspective to conceive research and produce data fails to render intersectionality as a methodological tool unfeasible, although it may limit result analysis and discussion. Such limitations can be addressed by proposing intersectional assumptions and comparing the results with literature related to the theme and object of study.</p>","PeriodicalId":21230,"journal":{"name":"Revista de saude publica","volume":"58 suppl 1","pages":"5s"},"PeriodicalIF":2.1,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceptions and practices of healthcare providers in providing HIV pre-exposure prophylaxis to trans adolescents and young adults and men who have sex with men. 医疗服务提供者在为变性青少年和年轻成人以及男男性行为者提供艾滋病毒暴露前预防时的看法和做法。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2020054005589
Ayra Zaine Rodrigues Urbano, Dulce Ferraz, Yzabelle de Lima Raymundo, Eliana Miura Zucchi

Objective: This study aims to understand the perceptions and practices of healthcare providers regarding the offer of HIV pre-exposure prophylaxis (PrEP) to gay and trans adolescents and young adults.

Methods: This qualitative research was developed as part of the PrEP1519 study, which was conducted from 2018 to 2021 to analyze the effectiveness of PrEP in adolescents and young adults. Data were collected from July 2020 to February 2021 at the municipality of São Paulo by combining participant observations and semi-structured interviews. The analytical process involved immersion in the empirical material and coding and categorizing it with the support of NVivo®. Interpretation followed the hermeneutic-dialectical principle and had the concept of Care in health practices as its horizon.

Results: The construction of trust-based relationships followed practices that acknowledge the uniqueness of youth and their demands and sought to strengthen their autonomy. Sensitive and supportive listening was pointed out as a welcoming practice that propelled care actions. Welcoming attitudes and support in facing stigma and violence (related or not to the use of PrEP) acknowledged the need to support adolescents and young adults to develop autonomy for prevention. The use of language close to young people's everyday life favored the construction of relationships of trust and positively influenced the development of autonomy and adherence to PrEP. The tension between technical and practical success occurred in the idealized search for adult-centric normativity as opposed to intersubjectivity.

Conclusion: The perceptions and practices of healthcare providers are aligned with the concept of Care as they include actions beyond technical knowledge and recognize the contexts that increase the vulnerability of adolescents and young adults to HIV.

研究目的本研究旨在了解医疗服务提供者对向男同性恋和变性青少年和年轻成人提供艾滋病暴露前预防(PrEP)的看法和做法:这项定性研究是 PrEP1519 研究的一部分,该研究于 2018 年至 2021 年进行,旨在分析 PrEP 在青少年和年轻成人中的有效性。数据收集工作于 2020 年 7 月至 2021 年 2 月在圣保罗市进行,采用了参与者观察和半结构化访谈相结合的方式。分析过程包括沉浸在经验材料中,并在 NVivo® 的支持下对其进行编码和分类。解释遵循诠释学-辩证法原则,并以医疗实践中的 "关怀 "概念为视角:结果:以信任为基础的关系的建立遵循了承认青年的独特性及其需求并努力加强其自主性的做法。敏感和支持性的倾听被认为是推动关爱行动的欢迎做法。在面对污名化和暴力(无论是否与使用 PrEP 有关)时,欢迎的态度和支持承认有必要支持青少年和年轻成人发展自主预防能力。使用贴近年轻人日常生活的语言有利于建立信任关系,对发展自主性和坚持使用 PrEP 有积极影响。技术上的成功与实践上的成功之间的矛盾在于对以成人为中心的规范性的理想化追求,而不是主体间性:医疗服务提供者的观念和实践与 "关怀 "的概念是一致的,因为他们的行动超越了技术知识,并认识到了增加青少年和年轻成年人感染艾滋病毒风险的环境。
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引用次数: 0
Prevalence of hepatitis among young men who have sex with men and transgender women in Brazil. 巴西男男性行为者和变性女性中的肝炎流行率。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2020054005555
Carina Carvalho Dos Santos, Beo Oliveira Leite, Fernanda Washington de Mendonça Lima, Laio Magno, Alexandre Grangeiro, Mateus Westin, Daniel Lima de Moura, Inês Dourado

Objective: Viral hepatitis and sexually transmitted infections disproportionally affect men who have sex with men (MSM) and transgender women (TGW). However, only a few studies have evaluated the prevalence of hepatitis in these populations, especially in youths and adolescents. This study aimed to estimate the prevalence of biomarkers for hepatitis A, B, and C among young and adolescent MSM and TGW in three Brazilian municipalities.

Methods: Baseline data were collected from a combination of HIV prevention cohort of young and adolescent MSM (AMSM) and TGW (ATGW) aged 15-19 years in three Brazilian municipalities. A social behavioral questionnaire was applied, and immunoassays were performed to detect antibodies against hepatitis A (anti- HAV IgG and IgM), hepatitis B (anti-HBc and anti-HBs), and hepatitis C virus (anti-HCV); testing for the active hepatitis B marker, HBsAg, was also performed. The prevalence of reactive tests and 95% confidence interval (CI) for proportions were measured.

Results: The prevalence of naturally or artificially acquired immunity for hepatitis A totaled 17.7% (95%CI: 15.4-20.4), whereas that of acute infection, 0.4% (95%CI: 0.2-1.2). For hepatitis B and C, prevalence rates totaled 2.8% (95%CI: 1.8-4.4) and 0.2% (95%CI: 0.1-1.1), respectively. About 25.7% (95%CI: 22.4-29.4) of participants were non-reactive for anti-HBc and reactive for anti-HBs, the latter being a vaccine marker for hepatitis B.

Conclusions: The investigation of viral hepatitis biomarkers among vulnerable populations enables the early identification of infections, the provision of timely treatment, and an opportunity to point out the need to expand vaccination coverage.

目的:病毒性肝炎和性传播感染对男男性行为者 (MSM) 和变性女性 (TGW) 的影响尤为严重。然而,只有少数研究评估了肝炎在这些人群中的流行情况,尤其是在青少年中的流行情况。本研究旨在估算巴西三个城市的青年和青少年 MSM 和变性女性中甲型、乙型和丙型肝炎生物标志物的流行率:从巴西三个城市 15-19 岁的青年和青少年 MSM(ASM)和 TGW(ATGW)艾滋病预防队列中收集了基线数据。调查采用了社会行为问卷,并进行了免疫测定,以检测甲型肝炎抗体(抗 HAV IgG 和 IgM)、乙型肝炎抗体(抗 HBc 和抗 HBs)和丙型肝炎病毒抗体(抗 HCV);还进行了活动性乙型肝炎标志物 HBsAg 的检测。测量了反应性检测的流行率和比例的 95% 置信区间 (CI):结果:甲型肝炎自然或人工获得免疫力的患病率为 17.7%(95% 置信区间:15.4-20.4),而急性感染的患病率为 0.4%(95% 置信区间:0.2-1.2)。乙型肝炎和丙型肝炎的感染率分别为 2.8%(95%CI:1.8-4.4)和 0.2%(95%CI:0.1-1.1)。约 25.7%(95%CI:22.4-29.4)的参与者对抗-HBc 无反应,对抗-HBs 有反应,后者是乙型肝炎的疫苗标记物:在易感人群中调查病毒性肝炎生物标志物有助于及早发现感染,及时提供治疗,并有机会指出扩大疫苗接种覆盖面的必要性。
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引用次数: 0
Recent HIV infections and estimated HIV incidence among adolescents from key populations. 重点人群中青少年最近的艾滋病毒感染情况和估计的艾滋病毒发病率。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2020054005997
Diana Zeballos, Fabiane Soares, Laio Magno, Celia Landmann Szwarcwald, Orlando Ferreira, Mateus Westin, Dirceu Greco, Alexandre Grangeiro, Inês Dourado

Objective: To identify recent HIV-1 infection and estimate HIV incidence among adolescent men who have sex with men (AMSM) and transgender women (ATGW) in Brazil.

Methods: From January to December 2020, a cross-sectional analysis was conducted with baseline data from the PrEP1519 study, an HIV pre-exposure prophylaxis (PrEP) demonstration cohort in Brazil among sexually active AMSM/ATGW aged 15-19. For enrollment, participants were screened with a fourth-generation HIV rapid test. The recent infection testing algorithm (RITA) included a recency assay in blood specimens, viral load, and CD4 cell count prior to antiretroviral treatment use. Among these participants, RITA-based HIV incidence was estimated using a mean duration of recency infection of 214 days and a false-recent rate of 0.02.

Results: Out of the 494 participants screened, 21 tested positive for HIV. Following RITA, five adolescents had a recent HIV infection, 14 had long-term infections, and two did not have blood specimens available. We classified these two participants as long-term infection cases due to CD4 cell counts and previous use of antiretroviral treatment. Among those who tested positive, all but one were AMSM (94.7%), 73.6% were aged 18-19, and 76.2% were non-White. The HIV prevalence was 4.2%, and the estimated HIV incidence was 1.7%.

Conclusions: The estimated incidence highlights the need for targeted HIV prevention interventions, such as PrEP, for sexual minority adolescents. Integrating RITA into routine HIV testing services for this population provides valuable information on the current HIV epidemic. This strategy can aid in monitoring the effectiveness of prevention efforts and improving early entry to HIV care.

目的在巴西的青少年男男性行为者(ASM)和变性女性(ATGW)中识别近期的 HIV-1 感染情况并估计 HIV 发病率:2020 年 1 月至 12 月,我们利用 PrEP1519 研究的基线数据进行了横断面分析,该研究是巴西的一项艾滋病暴露前预防(PrEP)示范队列研究,研究对象为 15-19 岁的性活跃男男性行为者/变性女性。参与者在注册时接受了第四代 HIV 快速检测。近期感染检测算法(RITA)包括在使用抗逆转录病毒治疗前对血液标本、病毒载量和 CD4 细胞计数进行复发检测。在这些参与者中,基于 RITA 的艾滋病毒发病率是根据平均 214 天的复发感染期和 0.02 的假复发率估算的:在接受筛查的 494 名参与者中,有 21 人的 HIV 检测呈阳性。经过 RITA 检测,5 名青少年近期感染过 HIV,14 名青少年长期感染,2 名青少年没有血液标本。根据 CD4 细胞计数和之前使用抗逆转录病毒治疗的情况,我们将这两名参与者归类为长期感染病例。在检测结果呈阳性的人群中,除一人外,其余均为 AMSM(94.7%),73.6% 年龄在 18-19 岁之间,76.2% 为非白人。艾滋病毒感染率为 4.2%,艾滋病毒发病率估计为 1.7%:估计的发病率凸显了对性少数群体青少年采取有针对性的艾滋病预防干预措施(如 PrEP)的必要性。将 RITA 纳入该人群的常规 HIV 检测服务,可提供有关当前 HIV 流行情况的宝贵信息。这一策略有助于监测预防工作的有效性,并改善早期接受 HIV 护理的情况。
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引用次数: 0
Risk and pleasure in the era of pharmacologically safe sex. 药理安全性行为时代的风险与快感。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2024058005962
Filipe Mateus Duarte, Sandra Assis Brasil, Mônica Lima, Jardel da Silva Vidal, Laio Magno, Inês Dourado, Luís Augusto Vasconcelos da Silva

Objective: This article discusses how Pre-Exposure Prophylaxis (PrEP) and the undetectable viral load=untransmissible (UVL=U) have produced reconfigurations in the contexts of affective-sexual encounters of young gay men/men who have sex with men (MSM) living with HIV (YLHIV).

Methods: In-depth interviews were conducted with nine YLHIV, aged 18 to 29, from two studies conducted in Salvador, Bahia, in 2019 and 2021. The narratives focused on unprecedented events in the prevention and treatment of HIV/AIDS, which have allowed experiences of greater intimacy and safety but also challenges and tensions in affective-sexual relationships.

Results: Different moments in the experience of living with HIV reveal different narratives of YLHIV concerning the new PrEP and UVL biotechnologies. Concerns surrounding possible HIV transmission or the obligation to reveal serology are more prominent among young people with the most recent diagnosis. In contrast, those with more extended serology experience are more comfortable and confident in the face of new technologies and their significant effects on sexual encounters. However, controversies remain regarding the moral and behavioral consequences of their use. Some YLHIV re-update concerns and bring reports about the continuity of stigma toward people living with HIV. Others emphasize the benefits of biomedical advances, opening up new interactive possibilities, including without the use of condoms, highlighting the existence of other practices, knowledge, dynamics, and ways of negotiating risk/care, with tensions in the field of sexuality itself.

Conclusions: We reiterate the need to resume public policies in the field of HIV/AIDS beyond biomedical strategies, highlighting vulnerabilities, the dissemination of information about new HIV prevention and treatment technologies, respect for people's autonomy in their preventive choices, and the development of strategies to combat the stigma associated with HIV/AIDS.

目的:本文讨论了暴露前预防(PrEP)和检测不到病毒载量=不可传播(UVL=U)如何在感染艾滋病毒的年轻男同性恋/男男性行为者(MSM)(YLHIV)的情感-性接触背景中产生重构:分别于 2019 年和 2021 年在巴伊亚州萨尔瓦多市进行的两项研究中,对九名 18 至 29 岁的青年艾滋病毒感染者进行了深入访谈。叙述的重点是艾滋病毒/艾滋病预防和治疗过程中发生的前所未有的事件,这些事件让人们体验到了更亲密、更安全的关系,但也带来了情感-性关系中的挑战和紧张:结果:艾滋病毒感染者在不同时期的经历揭示了 YLHIV 对新型 PrEP 和 UVL 生物技术的不同叙述。在最近确诊的年轻人中,围绕可能的 HIV 传播或披露血清学信息的义务的担忧更为突出。相比之下,那些有更多血清学经验的人在面对新技术及其对性接触的重大影响时则更加从容和自信。然而,关于使用这些技术的道德和行为后果仍存在争议。一些 YLHIV 重新更新了人们的担忧,并带来了关于对 HIV 感染者的持续污名化的报告。另一些人则强调生物医学进步带来的益处,开辟了新的互动可能性,包括不使用安全套的可能性,强调了其他做法、知识、动态和风险/护理谈判方式的存在,以及性行为领域本身的紧张关系:我们重申,有必要在生物医学战略之外,恢复艾滋病毒/艾滋病领域的公共政策,强调脆弱性,传播有关新的艾滋病毒预防和治疗技术的信息,尊重人们在预防选择方面的自主权,以及制定消除与艾滋病毒/艾滋病相关的耻辱感的战略。
{"title":"Risk and pleasure in the era of pharmacologically safe sex.","authors":"Filipe Mateus Duarte, Sandra Assis Brasil, Mônica Lima, Jardel da Silva Vidal, Laio Magno, Inês Dourado, Luís Augusto Vasconcelos da Silva","doi":"10.11606/s1518-8787.2024058005962","DOIUrl":"10.11606/s1518-8787.2024058005962","url":null,"abstract":"<p><strong>Objective: </strong>This article discusses how Pre-Exposure Prophylaxis (PrEP) and the undetectable viral load=untransmissible (UVL=U) have produced reconfigurations in the contexts of affective-sexual encounters of young gay men/men who have sex with men (MSM) living with HIV (YLHIV).</p><p><strong>Methods: </strong>In-depth interviews were conducted with nine YLHIV, aged 18 to 29, from two studies conducted in Salvador, Bahia, in 2019 and 2021. The narratives focused on unprecedented events in the prevention and treatment of HIV/AIDS, which have allowed experiences of greater intimacy and safety but also challenges and tensions in affective-sexual relationships.</p><p><strong>Results: </strong>Different moments in the experience of living with HIV reveal different narratives of YLHIV concerning the new PrEP and UVL biotechnologies. Concerns surrounding possible HIV transmission or the obligation to reveal serology are more prominent among young people with the most recent diagnosis. In contrast, those with more extended serology experience are more comfortable and confident in the face of new technologies and their significant effects on sexual encounters. However, controversies remain regarding the moral and behavioral consequences of their use. Some YLHIV re-update concerns and bring reports about the continuity of stigma toward people living with HIV. Others emphasize the benefits of biomedical advances, opening up new interactive possibilities, including without the use of condoms, highlighting the existence of other practices, knowledge, dynamics, and ways of negotiating risk/care, with tensions in the field of sexuality itself.</p><p><strong>Conclusions: </strong>We reiterate the need to resume public policies in the field of HIV/AIDS beyond biomedical strategies, highlighting vulnerabilities, the dissemination of information about new HIV prevention and treatment technologies, respect for people's autonomy in their preventive choices, and the development of strategies to combat the stigma associated with HIV/AIDS.</p>","PeriodicalId":21230,"journal":{"name":"Revista de saude publica","volume":"58 suppl 1","pages":"7s"},"PeriodicalIF":2.1,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with condomless anal sex among adolescent men who have sex with men and transgender women in three Brazilian state capitals: a PrEP1519 study. 巴西三个州府的男男性行为者和变性妇女中与无套肛交相关的因素:PrEP1519 研究。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.11606/s1518-8787.2020054005462
Rijone Rosário, Inês Dourado, Marcos Pereira, Lorenza Dezanet, Dirceu Greco, Alexandre Grangeiro, Laio Magno

Objective: To analyze the factors that increase the practice of condomless anal sex (CAS) among adolescent men who have sex with men (AMSM) and adolescent travestis and transgender women (ATGW) in three Brazilian state capitals.

Methods: PrEP1519 is a prospective, multicenter cohort study demonstrating the effectiveness of human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) among AMSM and ATGW aged from 15 to 19 years in three Brazilian state capitals. The analyses were performed with baseline cohort data, including 1,418 adolescents enrolled from 2019 to 2021. The outcome studied was CAS in the last six months, and the potentially associated factors were sociodemographic, behavioral, healthcare, and history of violence and discrimination. Descriptive, bivariate, and multivariate analyses were conducted. Adjusted prevalence ratios (aPRs) and 95% confidence intervals (95%CI) were estimated.

Results: Most of the participants were AMSM (91.5%), aged 18 to 19 years (75.9%), Black (40.5%), with secondary or higher education in progress (92.7%), with CAS during the first sexual intercourse (54.2%), sexual initiation before the age of 14 (43.4%), and history of group sex (24.6%) and transactional sex (14.6%). The prevalence of CAS in the last six months was 80.6% (95%CI 78.5%-82.6%). Adolescents who reported condomless first sexual intercourse (aPR: 1.18; 95%CI 1.10-1.25), use of psychoactive substances (aPR: 1.09; 95%CI 1.03-1.16), and transactional sex (aPR: 1.11; 95%CI 1.04-1.20) had a higher prevalence of CAS in the last six months. We also found that those aged 15 to 17 years had a higher prevalence of CAS than those aged 18 to 19 (aPR: 1.07; 95%CI 0.99-1.13).

Conclusions: The prevalence of CAS was high among AMSM and ATGW, being associated with practices that may increase the risk of sexually transmitted infections (STIs). Therefore, it is recommended to strengthen sexual health programs for young people that address the issue of sexuality and STI prevention, as well as to expand access to preventive methods, such as condoms and PrEP.

目的分析巴西三个州府的青少年男男性行为者(ASM)和青少年易性癖者及变性女性(ATGW)中无套肛交(CAS)行为增加的因素:PrEP1519 是一项前瞻性的多中心队列研究,它证明了在巴西三个州首府 15 至 19 岁的男男性行为者(ASMM)和变性女性(ATGW)中进行人类免疫缺陷病毒(HIV)暴露前预防(PrEP)的有效性。分析使用的是基线队列数据,其中包括 2019 年至 2021 年注册的 1418 名青少年。研究的结果是最近六个月的CAS,潜在的相关因素包括社会人口学、行为学、医疗保健以及暴力和歧视史。研究进行了描述性、双变量和多变量分析。对调整后的流行率(aPRs)和95%置信区间(95%CI)进行了估计:大部分参与者为 AMSM(91.5%)、18 至 19 岁(75.9%)、黑人(40.5%)、正在接受中等或高等教育(92.7%)、首次性交时有 CAS(54.2%)、14 岁前开始性行为(43.4%)、有群交史(24.6%)和性交易史(14.6%)。过去六个月中使用安全套的比例为 80.6%(95%CI 78.5%-82.6%)。报告无安全套初次性交(aPR:1.18;95%CI 1.10-1.25)、使用精神活性物质(aPR:1.09;95%CI 1.03-1.16)和性交易(aPR:1.11;95%CI 1.04-1.20)的青少年在过去六个月中的 CAS 患病率较高。我们还发现,15 至 17 岁人群的 CAS 患病率高于 18 至 19 岁人群(aPR:1.07;95%CI:0.99-1.13):ASM和ATGW的CAS患病率很高,这与可能增加性传播感染(STI)风险的行为有关。因此,建议加强针对年轻人的性健康计划,以解决性行为和性传播感染预防问题,并扩大避孕套和 PrEP 等预防方法的使用范围。
{"title":"Factors associated with condomless anal sex among adolescent men who have sex with men and transgender women in three Brazilian state capitals: a PrEP1519 study.","authors":"Rijone Rosário, Inês Dourado, Marcos Pereira, Lorenza Dezanet, Dirceu Greco, Alexandre Grangeiro, Laio Magno","doi":"10.11606/s1518-8787.2020054005462","DOIUrl":"10.11606/s1518-8787.2020054005462","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the factors that increase the practice of condomless anal sex (CAS) among adolescent men who have sex with men (AMSM) and adolescent travestis and transgender women (ATGW) in three Brazilian state capitals.</p><p><strong>Methods: </strong>PrEP1519 is a prospective, multicenter cohort study demonstrating the effectiveness of human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) among AMSM and ATGW aged from 15 to 19 years in three Brazilian state capitals. The analyses were performed with baseline cohort data, including 1,418 adolescents enrolled from 2019 to 2021. The outcome studied was CAS in the last six months, and the potentially associated factors were sociodemographic, behavioral, healthcare, and history of violence and discrimination. Descriptive, bivariate, and multivariate analyses were conducted. Adjusted prevalence ratios (aPRs) and 95% confidence intervals (95%CI) were estimated.</p><p><strong>Results: </strong>Most of the participants were AMSM (91.5%), aged 18 to 19 years (75.9%), Black (40.5%), with secondary or higher education in progress (92.7%), with CAS during the first sexual intercourse (54.2%), sexual initiation before the age of 14 (43.4%), and history of group sex (24.6%) and transactional sex (14.6%). The prevalence of CAS in the last six months was 80.6% (95%CI 78.5%-82.6%). Adolescents who reported condomless first sexual intercourse (aPR: 1.18; 95%CI 1.10-1.25), use of psychoactive substances (aPR: 1.09; 95%CI 1.03-1.16), and transactional sex (aPR: 1.11; 95%CI 1.04-1.20) had a higher prevalence of CAS in the last six months. We also found that those aged 15 to 17 years had a higher prevalence of CAS than those aged 18 to 19 (aPR: 1.07; 95%CI 0.99-1.13).</p><p><strong>Conclusions: </strong>The prevalence of CAS was high among AMSM and ATGW, being associated with practices that may increase the risk of sexually transmitted infections (STIs). Therefore, it is recommended to strengthen sexual health programs for young people that address the issue of sexuality and STI prevention, as well as to expand access to preventive methods, such as condoms and PrEP.</p>","PeriodicalId":21230,"journal":{"name":"Revista de saude publica","volume":"58 suppl 1","pages":"8s"},"PeriodicalIF":2.1,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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