Alejandra Santana-Cruz, J. Flores-Moreno, Roberto Guerra-González, M. Martínez-Ortiz
An anion exchange process was used to prepare pipemidic acid-MgFeAl composite from MgFeAl-Cl layered double hydroxide as inorganic matrix. The obtained hybrid material contains pipemidic acid anions as well as, in a less extent; carbonate and chloride species in its interlayer space. The antibacterial properties were evaluated against E. coli and S. typhi strains through dilution broth method. MgFeAl-Cl matrix resulted to be completely inactive against two bac-teria, while MgFeAl-PIP composite killed all colonies of E. coli after 90 min of exposure and showed a good activity to kill S. typhi bacteria at times as short as 120 min.
{"title":"Antibacterial Activity of Pipemidic Acid ions-MgFeAl Layered Double Hydroxide Hybrid Against E. coli and S. typhi","authors":"Alejandra Santana-Cruz, J. Flores-Moreno, Roberto Guerra-González, M. Martínez-Ortiz","doi":"10.29356/JMCS.V60I2.74","DOIUrl":"https://doi.org/10.29356/JMCS.V60I2.74","url":null,"abstract":"An anion exchange process was used to prepare pipemidic acid-MgFeAl composite from MgFeAl-Cl layered double hydroxide as inorganic matrix. The obtained hybrid material contains pipemidic acid anions as well as, in a less extent; carbonate and chloride species in its interlayer space. The antibacterial properties were evaluated against E. coli and S. typhi strains through dilution broth method. MgFeAl-Cl matrix resulted to be completely inactive against two bac-teria, while MgFeAl-PIP composite killed all colonies of E. coli after 90 min of exposure and showed a good activity to kill S. typhi bacteria at times as short as 120 min.","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"29 1","pages":"62-66"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85048373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rapid, one-pot, multi-component Route to 4,4'-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols)","authors":"A. Hassankhani","doi":"10.29356/JMCS.V59I1.6","DOIUrl":"https://doi.org/10.29356/JMCS.V59I1.6","url":null,"abstract":"A new, efficient and environmentally benign protocol for the one-pot, multicomponent synthesis of 4,4’-arylmethylene-bis(3-methyl-1-phenyl-1H-pyr...","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"16 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85468161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arturo Verduzco-Ramírez, Silvia Graciela Manzanilla-Dávila, María Eugenia Morales-Guillén, J. García-Ramos, Y. Toledaño-Magaña, Armando Marín-Becerra, M. Flores‐Álamo, L. Ortíz-Frade, Luis Fernando Olguín-Contreras, L. Ruiz-Azuara
One of the major public health problems worldwide is cancer followed by a significant number of deaths due to the resistance developed by bacteria or protozoan to the currently employed treatments. This generates an immediate need to develop drugs to treat these afflictions (illnesses, diseases). It has recently been identified that tumor cell, bacteria or protozoa are quite sensitive to oxidative stress induced by the same drugs. Due to this, it is important to develop new drugs to attend them, in this case, by using metals to increase the concentration of oxidative species. In the present work, the ligand 2,9-diformyl-4,7-diphenyl-1,10-phenanthroline and its corresponding coordination compounds with essential metals such as iron(II), cobalt(II), nickel(II), copper(II) and zinc(II) were synthesized. The electrochemical study shows that these compounds present three redox processes, all of them associated to the ligand. The compounds have shown inhibitory activity in vitro against human neuroblastoma CHP-212 cells, Escherichia coli and trophozoites of Entamoeba histolytica HM1:IMSS. It has been found that the inhibitory activity of the compounds studied is related to the first reduction process of the ligand. The correlation between the inhibitory activity and the red ox potential was linear. The inhibitory activity in CHP-212 increased with the increase of the compounds’ redox potential values, in contrast with the behavior observed in Escherichia coli , where the compounds with lowest redox potential values have had significantly higher inhibitory activity. Many of these coordination compounds have shown a higher inhibitory activity than those typically used in the treatment of cancer (cisplatin). The next step is to prove these compounds in vitro against healthy cells in order to verify its selectivity or cytotoxicity in these systems.
{"title":"Essential Metal-based drugs: Correlation between Redox Potential and Biological Activity of M2+ with a N2O2 Ligand","authors":"Arturo Verduzco-Ramírez, Silvia Graciela Manzanilla-Dávila, María Eugenia Morales-Guillén, J. García-Ramos, Y. Toledaño-Magaña, Armando Marín-Becerra, M. Flores‐Álamo, L. Ortíz-Frade, Luis Fernando Olguín-Contreras, L. Ruiz-Azuara","doi":"10.29356/JMCS.V61I2.258","DOIUrl":"https://doi.org/10.29356/JMCS.V61I2.258","url":null,"abstract":"One of the major public health problems worldwide is cancer followed by a significant number of deaths due to the resistance developed by bacteria or protozoan to the currently employed treatments. This generates an immediate need to develop drugs to treat these afflictions (illnesses, diseases). It has recently been identified that tumor cell, bacteria or protozoa are quite sensitive to oxidative stress induced by the same drugs. Due to this, it is important to develop new drugs to attend them, in this case, by using metals to increase the concentration of oxidative species. In the present work, the ligand 2,9-diformyl-4,7-diphenyl-1,10-phenanthroline and its corresponding coordination compounds with essential metals such as iron(II), cobalt(II), nickel(II), copper(II) and zinc(II) were synthesized. The electrochemical study shows that these compounds present three redox processes, all of them associated to the ligand. The compounds have shown inhibitory activity in vitro against human neuroblastoma CHP-212 cells, Escherichia coli and trophozoites of Entamoeba histolytica HM1:IMSS. It has been found that the inhibitory activity of the compounds studied is related to the first reduction process of the ligand. The correlation between the inhibitory activity and the red ox potential was linear. The inhibitory activity in CHP-212 increased with the increase of the compounds’ redox potential values, in contrast with the behavior observed in Escherichia coli , where the compounds with lowest redox potential values have had significantly higher inhibitory activity. Many of these coordination compounds have shown a higher inhibitory activity than those typically used in the treatment of cancer (cisplatin). The next step is to prove these compounds in vitro against healthy cells in order to verify its selectivity or cytotoxicity in these systems.","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"102 1","pages":"109-119"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85997220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Becerril, Miguel Ángel Martínez, E. García, Jorge Manuel Vázquez Ramos
Using the technique of Chromatin Immunoprecipitation, we have detected the formation of complexes between the homotrimer protein ring Proliferating Cell Nuclear Antigen, PCNA, and two fundamental regulators of the cell cycle, CdkA and Cyclin D4;2 along germination of maize seeds. This finding suggests the way PCNA participates in the control of the G1 phase, by allowing cyclin-kinase complexes to find and phosphorylate protein targets. Incidentally, PCNA may form a structure of a dimer of trimer when bound to the chromatin.
{"title":"Chromatin Bound PCNA is Complexed with Cell Cycle Protein Regulators as Determined by Chromatin Immunoprecipitation","authors":"N. Becerril, Miguel Ángel Martínez, E. García, Jorge Manuel Vázquez Ramos","doi":"10.29356/JMCS.V56I1.268","DOIUrl":"https://doi.org/10.29356/JMCS.V56I1.268","url":null,"abstract":"Using the technique of Chromatin Immunoprecipitation, we have detected the formation of complexes between the homotrimer protein ring Proliferating Cell Nuclear Antigen, PCNA, and two fundamental regulators of the cell cycle, CdkA and Cyclin D4;2 along germination of maize seeds. This finding suggests the way PCNA participates in the control of the G1 phase, by allowing cyclin-kinase complexes to find and phosphorylate protein targets. Incidentally, PCNA may form a structure of a dimer of trimer when bound to the chromatin.","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"37 1","pages":"10-14"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76798831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Burillo, J. Serrano-Gómez, J. Bonifacio-martinez
Polypropylene (PP) grafted with dimethylaminoethyl- methacrylate (DMAEMA), was prepared by irradiation with a 60 Co γ source. The obtained PP-g-DMAEMA was used to study the Cr(VI) ion adsorption as a function of contact time, initial pH, initial concen- tration of metal ion and temperature. Chromium adsorption data on PP-g-DMAEMA at various initial concentration fit well the Freundlich and Langmuir isotherms. The maximum adsorption capacity (amax) was found to be 0.3103 × 0 -4 mol g -1 . The thermodynamic parameters ΔH 0 , ΔG 0 and ΔS 0 were estimated showing the adsorption process to
用60 Co γ源辐照法制备了甲基丙烯酸二甲胺乙酯接枝聚丙烯(PP)。利用所制得的PP-g-DMAEMA研究了接触时间、初始pH、初始金属离子浓度和温度对Cr(VI)离子吸附的影响。PP-g-DMAEMA在不同初始浓度下对铬的吸附数据符合Freundlich和Langmuir等温线。最大吸附量(amax)为0.3103 × 0 -4 mol g -1。热力学参数ΔH 0， ΔG 0和ΔS 0表明吸附过程为
{"title":"Adsorption of chromium(VI) on radiation grafted N,N-dimethylaminoethylmethacrylate onto polypropylene, from aqueous solutions","authors":"G. Burillo, J. Serrano-Gómez, J. Bonifacio-martinez","doi":"10.29356/JMCS.V57I2.216","DOIUrl":"https://doi.org/10.29356/JMCS.V57I2.216","url":null,"abstract":"Polypropylene (PP) grafted with dimethylaminoethyl- methacrylate (DMAEMA), was prepared by irradiation with a 60 Co γ source. The obtained PP-g-DMAEMA was used to study the Cr(VI) ion adsorption as a function of contact time, initial pH, initial concen- tration of metal ion and temperature. Chromium adsorption data on PP-g-DMAEMA at various initial concentration fit well the Freundlich and Langmuir isotherms. The maximum adsorption capacity (amax) was found to be 0.3103 × 0 -4 mol g -1 . The thermodynamic parameters ΔH 0 , ΔG 0 and ΔS 0 were estimated showing the adsorption process to","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"73 1","pages":"80-84"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75985389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oxidative stress is frequently caused by an excess of free radicals and has been associated with a wide variety of health disor-ders. Therefore, finding strategies for scavenging free radicals has be-come an active area of research. This review summarizes, from a physicochemical perspective, relevant strategies to fight oxidative stress via antioxidants, including prevention, deactivation of oxidants, and repair of damaged targets. Different reaction mechanisms in-volved in the chemical protection exerted by antioxidants are dis-cussed, as well as their relative importance depending on several aspects. Some of them are the polarity of the environment, the pH of aqueous phase, and the chemical nature of the reacting radicals. Data that can currently be obtained from computational, quantum, chemis-try, protocols are detailed and their reliability is analyzed. Viable crite-ria to identify optimal antioxidants using such protocols are provided. Current challenges and future directions in this area of research are discussed. A large set of antioxidants are compared and their trends in activity, based on kinetic data, is provided.
{"title":"Free radicals induced oxidative stress at a molecular level: the current status, challenges and perspectives of computational chemistry based protocols","authors":"A. Galano","doi":"10.29356/JMCS.V59I4.81","DOIUrl":"https://doi.org/10.29356/JMCS.V59I4.81","url":null,"abstract":"Oxidative stress is frequently caused by an excess of free radicals and has been associated with a wide variety of health disor-ders. Therefore, finding strategies for scavenging free radicals has be-come an active area of research. This review summarizes, from a physicochemical perspective, relevant strategies to fight oxidative stress via antioxidants, including prevention, deactivation of oxidants, and repair of damaged targets. Different reaction mechanisms in-volved in the chemical protection exerted by antioxidants are dis-cussed, as well as their relative importance depending on several aspects. Some of them are the polarity of the environment, the pH of aqueous phase, and the chemical nature of the reacting radicals. Data that can currently be obtained from computational, quantum, chemis-try, protocols are detailed and their reliability is analyzed. Viable crite-ria to identify optimal antioxidants using such protocols are provided. Current challenges and future directions in this area of research are discussed. A large set of antioxidants are compared and their trends in activity, based on kinetic data, is provided.","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"48 1","pages":"231-262"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87554569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Alejandro Martínez-Villalobos, I. Figueroa, M. Suárez, G. Rodríguez, Omar Novelo Peralta, G. Reyes, Ismeli Alfonso López, Jorge Alejandro Verduzco Martínez, C. Trujillo
In this study, Al-Ni alloy ribbons in hypoeutectic, euctectic and hypereutectic compositions were obtained by melt spinning. The microstructural changes of the samples, from the as-cast to rapid solid-ification processes at different Cu wheel tangential velocities were characterized by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. The rapid solidification caused morphological transformation of the Al-Al3Ni microstructure from acicular in the as-cast condition to globular in the melt spun ribbons and the growth of the metastable Al9Ni2 intermetallic compound, which acted as reinforcing particles. Due to the increment of the Ni content and the presence of these intermetallic compounds, with size of ~5nm, distributed in the aluminum matrix, the hardness of the alloys significantly increased from the hypoeutectic (90 VHN) to the hypereutectic (205VHN) composition.
{"title":"Microstructural evolution of rapid solidified Al-Ni alloys","authors":"Manuel Alejandro Martínez-Villalobos, I. Figueroa, M. Suárez, G. Rodríguez, Omar Novelo Peralta, G. Reyes, Ismeli Alfonso López, Jorge Alejandro Verduzco Martínez, C. Trujillo","doi":"10.29356/JMCS.V60I2.75","DOIUrl":"https://doi.org/10.29356/JMCS.V60I2.75","url":null,"abstract":"In this study, Al-Ni alloy ribbons in hypoeutectic, euctectic and hypereutectic compositions were obtained by melt spinning. The microstructural changes of the samples, from the as-cast to rapid solid-ification processes at different Cu wheel tangential velocities were characterized by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. The rapid solidification caused morphological transformation of the Al-Al3Ni microstructure from acicular in the as-cast condition to globular in the melt spun ribbons and the growth of the metastable Al9Ni2 intermetallic compound, which acted as reinforcing particles. Due to the increment of the Ni content and the presence of these intermetallic compounds, with size of ~5nm, distributed in the aluminum matrix, the hardness of the alloys significantly increased from the hypoeutectic (90 VHN) to the hypereutectic (205VHN) composition.","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"63 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82660500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. A. El-Molla, G. El-Shobaky, N. H. Amin, M. N. Hammed, S. Sultan
CuO/MgO system having different compositions was pre- pared by impregnation method followed by calcination at 400-900 °C. The effect of CuO content, calcination temperature and doping with small amounts of K + species (1-3 mol %) on physicochemical, surface and catalytic properties of the system were investigated using XRD, adsorption of N2 at -196 °C, and conversion of isopropyl alcohol at 150-400 °C using a flow technique. The results revealed that the solids having the formulae 0.2 and 0.3 CuO/MgO calcined at 400 °C con- sisted of nanosized MgO and CuO as major phases together with Cu2O as minor phase. The BET-surface areas of different adsorbents are decreased by increasing CuO content, calcination temperature and K + - doping. MgO-support material showed very small catalytic activity in 2-propanol conversion. The investigated system behaved as selective catalyst for dehydrogenation of 2-propanol with selectivity > 80%. The catalytic activity increased by increasing CuO content and decreased by increasing the calcination temperature within 400-900 °C. K + - dop-
{"title":"Catalytic Properties of Pure and K+-Doped CuO/MgO System Towards 2-Propanol Conversion","authors":"S. A. El-Molla, G. El-Shobaky, N. H. Amin, M. N. Hammed, S. Sultan","doi":"10.29356/JMCS.V57I1.235","DOIUrl":"https://doi.org/10.29356/JMCS.V57I1.235","url":null,"abstract":"CuO/MgO system having different compositions was pre- pared by impregnation method followed by calcination at 400-900 °C. The effect of CuO content, calcination temperature and doping with small amounts of K + species (1-3 mol %) on physicochemical, surface and catalytic properties of the system were investigated using XRD, adsorption of N2 at -196 °C, and conversion of isopropyl alcohol at 150-400 °C using a flow technique. The results revealed that the solids having the formulae 0.2 and 0.3 CuO/MgO calcined at 400 °C con- sisted of nanosized MgO and CuO as major phases together with Cu2O as minor phase. The BET-surface areas of different adsorbents are decreased by increasing CuO content, calcination temperature and K + - doping. MgO-support material showed very small catalytic activity in 2-propanol conversion. The investigated system behaved as selective catalyst for dehydrogenation of 2-propanol with selectivity > 80%. The catalytic activity increased by increasing CuO content and decreased by increasing the calcination temperature within 400-900 °C. K + - dop-","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"1 1","pages":"36-42"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89218753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
La acilalacion de aldehidos estructuralmente diferentes ha sido realizada empleando Zn(BH4)2/Ac2O/DOWEX(R)50WX4 como un sistema novedoso, en 1-5 min a temperatura ambiente, con excelentes rendimientos de los productos (92-97%)
{"title":"Zn(BH4)2/Ac2O/DOWEX(R)50WX4: A Novel System for Acylalation of Aldehydes","authors":"D. Setamdideh","doi":"10.29356/JMCS.V58I2.183","DOIUrl":"https://doi.org/10.29356/JMCS.V58I2.183","url":null,"abstract":"La acilalacion de aldehidos estructuralmente diferentes ha sido realizada empleando Zn(BH4)2/Ac2O/DOWEX(R)50WX4 como un sistema novedoso, en 1-5 min a temperatura ambiente, con excelentes rendimientos de los productos (92-97%)","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"321 1","pages":"230-234"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79709833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chemical study of the aerial parts of Asclepias otarioides led to the isolation of four pentacyclic triterpenes and one cardenolide glycoside. This is the first report on the occurrence of the triterpenes 1, 3, and 4 in the genus Asclepias
通过化学分析，分离出4个五环三萜和1个核桃苷。本文首次报道了三萜1、3、4在芦笋属植物中的存在
{"title":"Secondary Metabolites from Asclepias otarioides","authors":"E. Maldonado, Sonia Amador, V. Juárez-Jaimes","doi":"10.29356/JMCS.V59I1.14","DOIUrl":"https://doi.org/10.29356/JMCS.V59I1.14","url":null,"abstract":"Chemical study of the aerial parts of Asclepias otarioides led to the isolation of four pentacyclic triterpenes and one cardenolide glycoside. This is the first report on the occurrence of the triterpenes 1, 3, and 4 in the genus Asclepias","PeriodicalId":21347,"journal":{"name":"Revista de la Sociedad Química de Mexico","volume":"41 1","pages":"50-52"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87250089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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