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[Bilateral pheochromocytoma associates with TMEM127 gene mutation. Report of one case]. 双侧嗜铬细胞瘤与TMEM127基因突变有关。报告1例]。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801115
José F Delgado, María Javiera Pérez E, Dasha Delgado, Carlos Lagos, René Baudrand, Thomas Uslar

Up to 40% of Pheochromocytoma/paraganglioma syndromes are associated with germline mutations. Therefore, they are considered familial and heritable. We report a 65 year old woman with hypertension, bilateral adrenal nodules found in the CT scan and elevated urinary metanephrines. Her genetic testing showed a c.117_120delGTCT TMEM127 gene mutation. She was subjected to a laparoscopic bilateral adrenal excision. After five years of follow up, no recurrence of the disease has been recorded.

高达40%的嗜铬细胞瘤/副神经节瘤综合征与种系突变有关。因此,它们被认为是家族性和遗传性的。我们报告一位65岁的女性高血压,在CT扫描中发现双侧肾上腺结节和尿肾上腺素升高。基因检测显示c.117_120delGTCT TMEM127基因突变。她接受了腹腔镜双侧肾上腺切除术。5年随访后,无复发记录。
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引用次数: 0
Perception about adult caregiving among Chilean adolescents. 智利青少年对成人照顾的认知。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801054
Marcelo Villalón C, Jorge Vilches Apablaza, Rodrigo Espinoza Farías, Catalina Poblete Achondo, Fabiola Werlinger C, Bernadette Paulaluengo Kanacri

Background: Chronic stress has short and long-term consequences during child and adolescent development if the stress is not mediated by adult care-giving.

Aim: To assess the perceptions of parental responsiveness, demand, and monitoring among seventh grade students.

Material and methods: We applied the Brief Parental Scale (developed and validated locally) asking 12 items about three dimensions, namely responsiveness, demand, and monitoring to 524 seventh grade students aged 12 years, 48% females, from eight public and private schools at Santiago.

Results: The overall response rate was 85%. While the scores were higher for mothers, a significantly constant gradient for the same dimensions (demand > responsiveness > monitoring) was verified for both parents.

Conclusions: The main hypothesis emerged from our study is that adolescents seem to perceive a discrepancy in terms of a relatively high demand and lower monitoring from parents/guardians towards them. The differences between fathers and mothers in adolescent care and the different perceptions by gender of adolescents about parental caregiving, require a further analysis.

背景:慢性压力在儿童和青少年发展过程中有短期和长期的后果,如果压力没有被成人照顾。目的:评估七年级学生对父母反应、需求和监督的认知。材料和方法:我们应用简短家长量表(本地开发和验证),对圣地亚哥8所公立和私立学校的524名12岁的七年级学生(48%为女生)进行了三个维度的12个项目,即反应性、需求和监测。结果:总有效率为85%。虽然母亲的得分更高,但在相同的维度(需求>反应性>监测)上,父母双方都有显著的恒定梯度。结论:从我们的研究中得出的主要假设是,青少年似乎在父母/监护人对他们的相对较高的要求和较低的监督方面感知到一种差异。父亲和母亲在青少年照顾方面的差异以及青少年对父母照顾的不同看法需要进一步分析。
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引用次数: 0
[Suicidal behavior, psychoactive substances use and quality of life in chilean adolescents]. [自杀行为,精神活性物质的使用和智利青少年的生活质量]。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801036
Fabiola Vilugrón Aravena, Temístocles Molina, María Eugenia Gras Pérez, Sílvia Font-Mayolas

Background: Suicidal behavior is a public health problem, and adolescents are one of the main risk groups.

Aim: To analyze the association among suicidal behavior, consumption of psychoactive substances, and Health Related Quality of Life (HRQoL) in adolescents attending schools in Valparaiso, Chile.

Material and methods: Five hundred-fifty adolescents enrolled in a public school participated in the study. HRQoL was evaluated through KIDSCREEN-27, while suicidal behavior and the consumption of psychoactive substances were measured with the Global School-based Student Health Survey (GSHS).

Results: The prevalence of suicidal behavior was higher in women and in those who used tobacco or marijuana in the last month. Respondents with a bad perception of physical well-being reported a higher frequency of suicidal ideation than those with a good perception (Odds ratio (OR): 2.24; 95% confidence: 1.49-3.36). Likewise the frequency of suicidal ideation was higher in those with a bad perception of psychological well-being (OR: 3.87; 95%CI: 2.09-7.71), and a bad perception of autonomy and relation with parents (OR:2.46; 95%CI: 1.34-4.54). Suicide planning was also associated with dimensions of autonomy and relation with parents (OR: 2.32; 95% CI: 1.23-4.38) and dimensions of friends and social support (OR: 1.86; 95%CI:1.05-3.28). Suicide attempt was associated with the dimensions of friendship and social support (OR: 1.83; 95%CI: 1.02-3.28) and school environment (OR: 1,92; 95%CI: 1,23-3,01).

Conclusions: Suicide ideation is associated with worse physical and psychological well-being. Suicide planning and suicide attempt is associated with a worse perception about the relation with parents or friends, social support, and school environment.

背景:自杀行为是一个公共卫生问题,青少年是自杀的主要危险群体之一。目的:分析智利瓦尔帕莱索地区在校青少年自杀行为、精神活性物质消费和健康相关生活质量(HRQoL)之间的关系。材料和方法:在一所公立学校注册的550名青少年参与了这项研究。HRQoL通过KIDSCREEN-27进行评估,而自杀行为和精神活性物质的消耗则通过全球校本学生健康调查(GSHS)进行测量。结果:自杀行为的流行率在女性和上个月使用过烟草或大麻的人群中较高。对身体健康感觉较差的受访者报告的自杀意念频率高于对身体健康感觉良好的受访者(比值比(OR): 2.24;95%置信区间:1.49-3.36)。同样,心理健康状况较差的学生出现自杀意念的频率也较高(OR: 3.87;95%CI: 2.09-7.71),以及对自主性和与父母关系的不良认知(OR:2.46;95%置信区间:1.34—-4.54)。自杀计划还与自主性和与父母的关系维度相关(OR: 2.32;95% CI: 1.23-4.38)和朋友和社会支持维度(OR: 1.86;95%置信区间:1.05—-3.28)。自杀企图与友谊和社会支持维度相关(OR: 1.83;95%CI: 1.02-3.28)和学校环境(OR: 1,92;95%置信区间:1 23-3 01)。结论:自杀意念与较差的身心健康状况有关。自杀计划和自杀企图与对父母或朋友关系、社会支持和学校环境的不良看法有关。
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引用次数: 0
[Peer to peer education among internal medicine residents using digital platforms]. [利用数字平台对内科住院医师进行点对点教育]。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801060
Andrés Ramírez Carreño, Felipe Carrillo Hurtado, Gabriel Uribe Sanzana

Background: COVID-19 impacted all areas of our society, and we took advantage of new technologies such as telemedicine to deliver information. Peer education is another tool that can be used.

Aim: To report the experience of peer education among residents using a digital platform.

Material and methods: A digital educational program was devised in which third year residents exposed different relevant topics in internal medicine to their first year peers using Zoom. The educational process was evaluated using a Likert scale.

Results: A high level of satisfaction was found among the respondents according to the scale.

Conclusions: There was a high level of satisfaction with the used methodology among first-year residents. A more exhaustive evaluation of this educational program should be worthwhile.

背景:新冠疫情影响到我们社会的各个领域,我们利用远程医疗等新技术来传递信息。同伴教育是另一个可以使用的工具。目的:报告居民使用数字平台进行同伴教育的经验。材料和方法:设计了一个数字教育计划,在这个计划中,第三年的住院医生使用Zoom向他们的一年级同龄人展示内科的不同相关主题。教育过程采用李克特量表进行评估。结果:根据量表,被调查者的满意度较高。结论:第一年住院医师对所使用的方法有很高的满意度。对这一教育计划进行更详尽的评估是值得的。
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引用次数: 0
[Subjective well-being, health status, functional capacity and social participation in Chilean older people]. [智利老年人的主观幸福感、健康状况、功能能力和社会参与]。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801010
Luis Sarmiento Loayza

Background: Chile is currently updating the Comprehensive Policy on Positive Aging, which establishes a positive association between Subjective Well-being, Self-perceived Health, Functional status, and Social Participation in older people.

Aim: To study the relationship between Subjective Well-being, General Health, Functional status, and Social Participation in older people in Chile.

Material and methods: In a cross-sectional observational study, 2.031 people aged 60 years and over were included in the National Health Survey 2016-2017 (ENS). The study included analysis of correlations between the relevant variables, in addition to binomial logistic regression with Subjective Well-being as a response variable, as well as the application of structural equation techniques (SEM).

Results: Subjective Well-being had a positive association with Self-perceived Health (Rho = 0.370), functional status (Rho = 0.360), and Social Participation (Rho = 0.290). However, in the logistic regression analysis only Self-perceived Health (OR = 0.293) and Functional status (OR = 0.932) had predictive capacity for Subjective Well-being.

Conclusions: The relevance of Self-perceived Health and Functionality in the sensation of Well-being among older people, reinforces the need to improve health care within a framework of a comprehensive policy for this age group.

背景:智利目前正在更新《积极老龄化综合政策》,该政策确立了老年人主观幸福感、自我感知健康、功能状态和社会参与之间的正相关关系。目的:研究智利老年人主观幸福感、总体健康、功能状态和社会参与之间的关系。材料与方法:在一项横断面观察性研究中,2031名60岁及以上的人被纳入2016-2017年国民健康调查(ENS)。本研究包括相关变量之间的相关性分析,以及以主观幸福感为响应变量的二项逻辑回归,以及结构方程技术(SEM)的应用。结果:主观幸福感与自我感知健康(Rho = 0.370)、功能状态(Rho = 0.360)和社会参与(Rho = 0.290)呈正相关。然而,在logistic回归分析中,只有自我感知健康(OR = 0.293)和功能状态(OR = 0.932)对主观幸福感具有预测能力。结论:自我感知健康和功能在老年人幸福感中的相关性,加强了在该年龄组综合政策框架内改善卫生保健的必要性。
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引用次数: 0
[Leadless pacemaker implantation. Case report]. 无铅起搏器植入。病例报告)。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801108
José Pardo G, Gonzalo Lira Lp, Roberto Marrero M, Jorge Egger Z, María Lorena Jofré Sm

We report 67-year-old woman with a sinus node dysfunction and diffuse conduction system disease, with a history of recurrent paroxysmal atrial fibrillation. She was admitted to the Hospital due to palpitations, dizziness, and vertigo, attributing the symptoms to the rhythm disorder described, for which the implantation of a pacemaker was indicated. With a history of tracheal cancer treated with radio and chemotherapy, and chronic steroid therapy for rheumatoid arthritis, she had an important limitation in vascular access for a conventional pacemaker, so, added to a high risk of infection, a decision was made to implant a leadless pacemaker. We discuss the electrocardiographic and clinical manifestations of sinus node disease, its relationship with oncological treatment and the indication for a permanent pacemaker, highlighting the characteristics of this new modality of artificial cardiac stimulation, for a special type of patients.

我们报告一位67岁的女性,患有窦房结功能障碍和弥漫性传导系统疾病,并有复发性阵发性心房颤动的病史。她因心悸、头晕和眩晕而入院,将这些症状归因于所描述的节律障碍,为此需要植入起搏器。她有气管癌的病史,曾接受过放疗和化疗,并因类风湿关节炎接受过慢性类固醇治疗,因此传统起搏器对血管通路有很大的限制,因此,考虑到感染的高风险,我们决定植入无铅起搏器。我们讨论了窦房结疾病的心电图和临床表现,它与肿瘤治疗的关系和永久起搏器的适应症,强调了这种新型人工心脏刺激的特点,为特殊类型的患者。
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引用次数: 0
[Chilean mental health law and its impact on biomedical research]. [智利精神卫生法及其对生物医学研究的影响]。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801123
Juan Alberto Lecaros, Sofía P Salas
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引用次数: 0
[Perfectionism, academic stress and social anxiety in female medical students and the risk for eating disorders]. [女医学生的完美主义、学业压力和社交焦虑与饮食失调的风险]。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801046
María Ignacia Mandiola, Marcelo Arancibia, Victoria Elton, Eva Madrid, Nicolás Meza, Jana Stojanova, Mariane Lutz, Fanny Leyton

Background: Both perfectionism and social anxiety have been described in patients with eating disorders (ED) and medical students. Academic stress also can increase the risk of developing ED.

Aim: To analyze the dimensions of perfectionism, social anxiety, and academic stress associated with the risk of developing ED in female medical students.

Material and methods: The Multidimensional Perfectionism Scale, the Liebowitz Social Anxiety Scale, the SISCO academic stress inventory and the Eating Attitudes Test-26, were applied to 163 female medical students from all levels of the career. The groups with and without risk of ED were compared according to these variables.

Results: Twenty-four percent of respondents were at risk of ED. There were significant differences between scores of perfectionism, social anxiety, and academic stress between respondents with and without risk for ED. In general, there was a significant correlation among the variables. In a multivariate analysis, the predictors of ED risk were the perception of academic stress (Odds ratio (OR) 1.09; 95% confidence intervals (CI) 1.03-1.16) and personal standards in the context of perfectionism (OR 1.16; 95% CI 1.06-1.27).

Conclusions: A substantial proportion of female medical students were at risk for ED. The risk of ED was determined mainly by academic stress and personal standards in the context of perfectionism. In this sample, social anxiety did not play a relevant role.

背景:完美主义和社交焦虑都被描述为饮食失调(ED)患者和医学生。目的:分析完美主义、社交焦虑和学业压力与女医学生ED发病风险的关系。材料与方法:采用多维完美主义量表、Liebowitz社交焦虑量表、SISCO学业压力量表和饮食态度测试(26)对163名女医学生进行调查。根据这些变量对有和无ED风险组进行比较。结果:24%的受访者有ED风险。在有ED风险和没有ED风险的受访者之间,完美主义、社交焦虑和学业压力的得分存在显著差异。总的来说,变量之间存在显著的相关性。在多变量分析中,ED风险的预测因子是学业压力感知(优势比(OR) 1.09;95%置信区间(CI) 1.03-1.16)和完美主义背景下的个人标准(OR 1.16;95% ci 1.06-1.27)。结论:相当比例的女医学生存在ED风险,其风险主要由学业压力和完美主义背景下的个人标准决定。在这个样本中,社交焦虑没有发挥相关作用。
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引用次数: 0
Does celiac neuropathy favour Guillain-Barre syndrome following immunisation with the CoronaVac vaccine? 接种冠状病毒疫苗后乳糜泻神经病变是否有利于格林-巴利综合征?
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801121
Josef Finsterer
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引用次数: 0
[Self-managed psychiatry seminars as a model of active student participation in undergraduate education]. [自我管理精神病学研讨会作为学生积极参与本科教育的典范]。
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2022-08-01 DOI: 10.4067/S0034-98872022000801087
Pablo Araya, Camila Martínez, Alejandro Revello, Constanza Caneo, Rodrigo Andrés Figueroa, Pablo Toro

In the last decade, medical students stood out as active agents in their training, which implies their involvement in the design, implementation, evaluation, and curricular co-governance. This article describes a model of active undergraduate student participation from 2014 to 2021 and compares the face-to-face and synchronous online modalities, later brought forward by the SARS-COV-2 pandemic. Annually, a call was made to UC School of Medicine undergraduate students to establish the topics and areas to be addressed during self-managed seminars. Then, medical students located in Chile were invited to attend the activity. Psychiatry was established as a priority topic in six out of eight years. Five seminars were conducted, the last two in synchronous online mode. The number of people enrolled in the online modality increased by 251% compared to the face-to-face modality (face-to-face mean = 133 ± 33 SD; online mean = 336 ± 24SD), with no significant differences in rates of attendance between modalities (Odds ratio (OR) = 1,12; 95% CI= 0,82 - 1,55; p = 0,45). The online modality was associated with a higher proportion of enrollees belonging to an institution outside the Metropolitan Region (OR 12,63; 95% CI = 8,64 - 18,46; p < 0,01). The self-managed psychiatry seminars correspond to a model of active undergraduate student participation, with the synchronous online modality representing an opportunity to massify it throughout the national territory.

在过去的十年中,医学生在他们的训练中表现出积极的角色,这意味着他们参与了课程的设计、实施、评估和共同治理。本文描述了2014年至2021年大学生积极参与的模式,并比较了后来因SARS-COV-2大流行而提出的面对面和同步在线模式。每年,我们都会向加州大学医学院的本科生发出呼吁,要求他们确定在自我管理研讨会期间要讨论的主题和领域。随后,智利的医科学生应邀参加了此次活动。精神病学在八年中有六年被确立为优先学科。共举办了五场研讨会,最后两场采用同步在线模式。与面对面的方式相比,参加在线模式的人数增加了251%(面对面的平均值= 133±33 SD;在线平均= 336±24SD),两种方式的出勤率无显著差异(优势比(OR) = 1,12;95% ci = 0,82 - 1,55;P = 0,45)。在线模式与属于大都会地区以外机构的较高比例的登记者相关(OR 12,63;95% ci = 8,64 - 18,46;P < 0.01)。自我管理的精神病学研讨会符合本科生积极参与的模式,同步的在线模式代表了在全国范围内大规模开展的机会。
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引用次数: 0
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Revista medica de Chile
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