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Acantholytic squamous cell carcinoma: Pathological study of three cases in Ecuador 厄瓜多尔棘溶性鳞状细胞癌3例病理分析
Pub Date : 2017-08-17 DOI: 10.18282/JSD.V2.I4.151
E. G. Aldás, G. Torres
Adenoid squamous cell carcinoma is an uncommon histopathological variant of squamous cell carcinoma characterized by acantholysis of tumor cells creating pseudolumina and the appearance of glandular differentiation. It is also known as pseudoglandular, pseudoangiosarcomatous, adenoid, epithelioma dyskeratoticum, or adenoacanthoma. In this article, we describe and analyze three cases of acantholytic cell carcinoma. The purpose is to verify if the data of our cases can be validated with scientific information. All our cases presented lesions in the face, and in one of them the developed tumor on the skin showed actinic keratosis. The other two tumors were located in the right side of the face, and both were big: the bigger tumor was approximately 8 × 4 cm and the other one with a size of 6 × 2.5 cm. Due to the size and location, they were both send to the oncologist for treatment. One of our cases showed metatypical carcinomas accompanied by acantholytic variant of squamous cell carcinoma. None of our cases presented metastasis. The histopathological finding were keratinized squamous tumor cell type, adenoid structures with round spaces with a defined wall of at least one-cell width, and spaces with isolated or group of dyskeratotic cells.
腺样鳞状细胞癌是一种罕见的鳞状细胞癌的组织病理学变异,其特征是肿瘤细胞的棘层溶解产生假腔,并出现腺分化。它也被称为假腺性、假血管肉瘤、腺样、角化不良上皮瘤或腺棘瘤。在这篇文章中,我们描述并分析了三例棘溶性细胞癌。目的是验证我们的案例数据是否可以用科学的信息进行验证。所有病例均表现为面部病变,其中一例皮肤肿瘤发展为光化性角化病。另外两个肿瘤位于面部右侧,均较大:较大的肿瘤约8 × 4 cm,另一个肿瘤约6 × 2.5 cm。由于肿瘤的大小和位置,他们都被送到肿瘤科医生那里接受治疗。我们的一个病例显示了异典型癌伴棘溶性变异型鳞状细胞癌。本组病例均未出现转移。组织病理学发现为角化的鳞状肿瘤细胞型,腺样体结构为圆形空间,具有至少一个细胞宽度的明确壁,空间中有分离的或成群的角化不良细胞。
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引用次数: 0
The efficacy and safety of a 70% glycolic acid peel with vitamin C for the treatment of acne scars 含维生素C的70%乙醇酸果皮治疗痤疮疤痕的有效性和安全性
Pub Date : 2017-08-03 DOI: 10.18282/JSD.V2.I4.94
Heng Jun Khee, L. M. May, Yang Shiyao Sam, Aw Chen Wee Derrick, Ho Sue-Ann
Acne scarring is a common complication associated with significant psychological distress. Both glycolic acid (GA) and vitamin C are known to improve the appearance of acne scarring. We performed a review of 13 patients treated with three 70% GA peels with vitamin C at four weeks apart. There was a statistically significant` improvement in acne scarring and post-inflammatory hyperpigmentation from the baseline. Maximal effects were noted four weeks after the third chemical peel. It has an excellent safety profile with no permanent adverse effects noted. A combination of 70% glycolic acid with vitamin C chemical peel is an efficacious, well-tolerated treatment of acne scarring in Asian skin. 
痤疮疤痕是一种常见的并发症与显著的心理困扰。已知乙醇酸(GA)和维生素C都能改善痤疮疤痕的外观。我们对13名接受三次70% GA换肤和维生素C治疗的患者进行了回顾,每隔四周进行一次。与基线相比,痤疮疤痕和炎症后色素沉着有统计学上的显著改善。在第三次化学脱皮4周后效果最大。它具有良好的安全性,没有永久性的不良反应。70%乙醇酸与维生素C化学果皮的组合是一种有效且耐受性良好的治疗亚洲皮肤痤疮疤痕的方法。
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引用次数: 2
Giant cell tumor of tendon sheath—Use of fine-needle aspiration cytology for diagnosis 腱鞘巨细胞瘤:细针穿刺细胞学诊断的应用
Pub Date : 2017-07-28 DOI: 10.18282/JSD.V2.I4.138
N. Meena, P. Arora

Giant cell tumour of the tendon sheath (GCTTS) is a slow-growing, usually painless benign lesion of soft tissues. We report the case of a 38-year-old male with a painless, slowly enlarging swelling on right thumb in order to highlight the role of fine-needle aspiration cytology (FNAC) in diagnosing GCTTS.

腱鞘巨细胞瘤(GCTTS)是一种生长缓慢,通常无痛的软组织良性病变。我们报告一例38岁男性,右拇指无痛,缓慢扩大肿胀,以强调细针穿刺细胞学(FNAC)在诊断GCTTS中的作用。
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引用次数: 0
IC plasty for reconstruction of axillary defect IC成形术重建腋窝缺损
Pub Date : 2017-05-29 DOI: 10.18282/JSD.V2.I3.157
S. Mazouz, A. Echchaoui, J. Hafidi, N. Gharib, A. Abbassi
Reconstruction of axillary defects following surgery or trauma has always been a significant challenge for plastic surgeons. A variety of reconstruction options are available, including directed cicatrization, skin grafts and local flaps, but all of these procedures may allow skin contracture and leave unsightly scars.
手术或外伤后腋窝缺损的重建一直是整形外科医生面临的重大挑战。有多种重建方法可供选择,包括直接愈合、皮肤移植和局部皮瓣,但所有这些方法都可能导致皮肤挛缩并留下难看的疤痕。
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引用次数: 0
Subungual glomus tumour excision: The nail plate flap technique 甲下血管球瘤切除术:甲板瓣技术
Pub Date : 2017-05-29 DOI: 10.18282/JSD.V2.I3.136
S. Mehrotra, V. Singh, U. Dadwal
Subungual glomus tumours, though rare, cause distressing symptoms and merit surgical treatment with minimal morbidity. Approaches to the nail bed over the years have varied from earlier nail excisions to trans/sub/periungal techniques. Nail plate preservation has beneficial effects on pain, and cosmesis and surgical modifications to ensure the same are desirable. We employed a simple nail preservation technique on six patients over the last seven years. After an accurate localization of the lesion based on pin test and MRI, a proximally-based nail plate flap was marked and elevated beyond the glomus. The tumour was removed through a linear nail-bed incision, following which the nail plate flap was reposited without suturing. All cases had gratifying relief of symptoms. Within a few weeks of the excision, no nail distortion was noticeable. No recurrences were noted on follow-up for one year. The nail flap transungal approach relies on accurate preoperative tumour localization. It ensures a protective post-operative cover with reduced pain. A minimalistic approach with no skin incisions ensures less morbidity and improved cosmesis with no nail deformity. The nail plate flap technique can be employed in selected cases for improved outcomes.
趾骨下血管球瘤,虽然罕见,引起痛苦的症状,值得手术治疗,发病率最低。多年来,甲床的治疗方法多种多样,从早期的甲切除到跨/下/周技术。甲板保存对疼痛有有益的影响,美容和手术修改以确保相同是可取的。在过去的七年中,我们对六名患者采用了简单的指甲保存技术。根据针试验和MRI准确定位病变后,近端甲板瓣被标记并升高到球囊外。通过甲床线性切口切除肿瘤,随后不缝合甲板瓣复位。所有病例均有令人满意的症状缓解。在切除后的几周内,指甲没有明显的变形。随访一年未见复发。经甲皮瓣入路依赖于术前准确的肿瘤定位。它可以确保术后保护,减少疼痛。简约的方法,无皮肤切口,确保更少的发病率和改善美容,没有指甲畸形。甲板瓣技术可用于特定病例,以改善预后。
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引用次数: 1
The story behind cryosurgery 冷冻手术背后的故事
Pub Date : 2017-05-09 DOI: 10.18282/JSD.V2.I3.123
S. Awad
Cryosurgery is used to describe the controlled destruction of tissue by freezing. Today, cryosurgery is widely practiced in medicine, so it would be interesting to know how the story of cryosurgery began. Here are some short stories behind the discovery and evolution of cryosurgery.
冷冻外科用于描述通过冷冻对组织进行有控制的破坏。今天,冷冻手术在医学上得到了广泛的应用,所以了解冷冻手术的故事是如何开始的会很有趣。这里有一些关于冷冻手术的发现和发展的小故事。
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引用次数: 1
Facial laser surgery 面部激光手术
Pub Date : 2017-04-12 DOI: 10.18282/JSD.V2.IT1.137
Shree Harsh, Surendra B. Patil
Lasers have a number of clinical applications on the face, ranging from aesthetic uses such as the rejuvenation of ageing face to functional ones such as the correction of bleeding vascular malformations. The vast growing uses of lasers on the face emphasises the need to have knowledge of the subject. Though the vast spectrum of lasers is very difficult to compile in an article, the authors give an overview of the application of lasers in the facial region and discuss the most defining treatment of the individual disease processes.
激光在面部有许多临床应用,从美容用途(如使衰老的面部恢复活力)到功能性用途(如纠正出血血管畸形)。激光在面部的广泛应用强调了对这一学科知识的需求。虽然在一篇文章中很难汇编激光的广泛光谱,但作者概述了激光在面部区域的应用,并讨论了个体疾病过程中最明确的治疗方法。
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引用次数: 1
Periocular syringomas – Successful treatment with fractional CO2 laser 眼周注射器瘤-分数CO2激光成功治疗
Pub Date : 2017-04-07 DOI: 10.18282/JSD.V2.IT1.145
A. Goldman, U. Wollina
Syringoma is a benign tumor of eccrine origin which arises from eccrine ducts. Syringomas are most commonly found on the eyelids in middle-aged women. Traditional treatments include surgical excision, curettage, peelings, dermabrasion and laser. We report on the successful use of fractional laser on periocular syringomas. A 53-year-old female patient with multiple periorbital syringomas underwent three sessions of fractional carbon dioxide (CO2) laser. Settings of 20 watts of power, 600 μm of spacing, 800 μs of dwell, time stack 2 (Smartxide DOT, DEKA, Florence, Italy) were used. The sessions were performed monthly. Significant improvement of the esthetic appearance was observed after three sessions. There was a decrease of visible syringomas associated with an evident improvement of the skin texture, skin quality and flaccidity. No side effects were observed. We suggested continuing the treatment but the patient was satisfied with the current aspect and result. In conclusion, fractional CO2 laser represents an effective treatment option for the treatment of periorbital syringomas.
性腺瘤是一种起源于内分泌管的良性肿瘤。青膜瘤最常见于中年妇女的眼睑。传统的治疗方法包括手术切除、刮除、脱皮、磨皮和激光。我们报告了分形激光治疗眼周注射器瘤的成功应用。一位53岁的女性患者患有多发性眶周注射器瘤,接受了三次二氧化碳激光治疗。设置为功率20瓦,间隔600 μm,停留时间800 μs,时间堆栈2 (Smartxide DOT, DEKA, Florence, Italy)。疗程每月进行一次。三个疗程后观察到美观外观有显著改善。随着皮肤质地、皮肤质量和松弛度的明显改善,可见的丁香瘤减少了。未观察到任何副作用。我们建议继续治疗,但患者对目前的情况和结果都很满意。综上所述,分数CO2激光是治疗眶周注射器瘤的有效选择。
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引用次数: 1
Expression of chemokine receptors in angiosarcoma 趋化因子受体在血管肉瘤中的表达
Pub Date : 2017-03-22 DOI: 10.18282/JSD.V2.I2.127
T. Kishi, Yuki Yamamoto, C. Kaminaka, Seiko Toyozawa, H. Matsunaka, F. Furukawa
Angiosarcoma is a rapidly progressing malignant skin tumor associated with a poor prognosis. We report an immunohistochemical investigation of chemokine receptors in angiosarcoma. The aim is to investigate chemokine receptor expression and, if it is expressed, to histologically discuss its association with age, sex, development site, and histological type. Analyzed were 12 angiosarcoma samples (mean patient age: 75.7 years old) collected by biopsy or surgery from patients at our department by comparing with 4 granuloma telangiectaticum samples (mean patient age: 37.5 years old) and 16 healthy skin samples as controls. CXCR4, CCR6, CCR7, and SDF-1 expressions were immunohistochemically investigated. CXCR4 expression was positive in 6 of the 12 samples. CCR6 and CCR7 were negative in all samples. SDF-1 was positive in 4 samples. Out of the 6 CXCR4-positive samples, 4 were SDF-1-positive. No significant difference associated with age, sex, development site, or histological type was noted in the expression of CXCR4, CCR6, CCR7, or SDF-1. Although CXCR4 is regarded as an index of tumor aggressiveness of malignant melanoma, it is suggested that chemokine receptors, such as CXCR4, do not serve as useful markers of angiosarcoma.
血管肉瘤是一种进展迅速的恶性皮肤肿瘤,预后较差。我们报告了血管肉瘤中趋化因子受体的免疫组织化学研究。目的是研究趋化因子受体的表达,如果表达,组织学上讨论其与年龄、性别、发育部位和组织学类型的关系。分析我科患者活检或手术采集血管肉瘤标本12例(患者平均年龄75.7岁),与肉芽肿毛细血管扩张标本4例(患者平均年龄37.5岁)和健康皮肤标本16例作为对照。免疫组织化学检测CXCR4、CCR6、CCR7和SDF-1的表达。12例标本中有6例CXCR4表达阳性。CCR6、CCR7均为阴性。4个样本中SDF-1呈阳性。在6例cxcr4阳性样本中,4例sdf -1阳性。CXCR4、CCR6、CCR7或SDF-1的表达与年龄、性别、发育部位或组织学类型无显著差异。虽然CXCR4被认为是恶性黑色素瘤肿瘤侵袭性的指标,但有研究表明趋化因子受体,如CXCR4,不能作为血管肉瘤的有用标志物。
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引用次数: 0
Value of exposure: External postings of plastic surgery trainees in India 曝光价值:印度整形外科实习生的外部职位
Pub Date : 2017-03-17 DOI: 10.18282/JSD.V2.I2.135
Rahul Bamal, Amrita Mandal
The medical education system in India is not perfect and recent developments have again raised questions about the working and conduct of the Medical Council of India. There are loud calls for standardization and, in the midst of this chaos, there are always people who strive for excellence, who try to absorb knowledge at every opportunity and who can burst onto the mega screen anytime. Our aim should be to provide them with the congenial environment in which they can flourish.
印度的医学教育体系并不完善,最近的事态发展再次引发了对印度医学委员会工作和行为的质疑。标准化的呼声很高,在这种混乱中,总有人追求卓越,他们试图抓住每一个机会吸收知识,他们随时可以出现在大屏幕上。我们的目标应该是为他们提供一个适宜的环境,使他们能够茁壮成长。
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引用次数: 0
期刊
Journal of Surgical Dermatology
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