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International Journal of Radiology & Radiation Therapy最新文献

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Long term survival in diffuse infiltrative brainstem gliomas in children and adolescents treated with radiatherapy and Nimotuzumab 放疗和尼莫单抗治疗儿童和青少年弥漫性浸润性脑干胶质瘤的长期生存率
Pub Date : 2018-08-28 DOI: 10.15406/IJRRT.2018.05.00176
J. Alert, I. Chon, J. Valdes, R. Ropero, J. Reno, Migdalia Perez, M. Forteza, Débora García
Background Brainstem gliomas have a short survival time chemotherapy has not improved outcome We report the result obtained with the combination of Radiotherapy and the monoclonal antibody Nimotuzumab in a series of these tumors Material and methods children and adolescents treated with irradiation and Nimotuzumab were included between Jan and December all with the diagnosis of diffuse infiltrative pontine gliomas DIPG irradiated at the Instituto Nacional de Oncologia y Radiobiologia in Havana Cuba Nimotuzumab was applied during the period receiving Radiotherapy and them monthly for one year or more Results Median age at diagnosis was years range years old median survival was months and Kaplan Meier survival was at years and at years established till years Addition of Nimotuzumab was safe and well tolerated Conclusion Combination of Nimotuzumab and Radiotherapy is safe and could increase survival
背景:脑干胶质瘤生存时间短,化疗并没有改善预后。我们报告了放疗和单克隆抗体尼莫单抗联合治疗一系列此类肿瘤的结果。材料和方法:在1月至12月期间,在哈瓦那国家肿瘤放射生物学研究所接受放疗和尼莫单抗治疗的儿童和青少年均被诊断为弥漫性浸润性脑桥胶质瘤结果诊断时中位年龄为年,年龄中位生存期为月,Kaplan Meier生存期为年,建立至年。添加尼莫单抗是安全的,耐受性良好结论尼莫单抗与放疗联合使用是安全的,可提高生存率
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引用次数: 0
The new wave device for physiotherapy of radiation induced diseases 放射诱发疾病物理治疗的新波装置
Pub Date : 2018-08-09 DOI: 10.15406/ijrrt.2018.5.00174
V. Bebeshko, L. Shvaiko, I. Homolyako, O. Shalimov, V. Grynchyshyn
The paper contains characteristics and recomendations for the use of the Wave Device for the prevention and treatment of the Radiation induced Diseasesby reducing reactive oxygen radicals ROSs Information obtained from experimental animals indicates a positive effect on the reduction of reactive oxygen species in ratsin the protection of radiation sensitive cells and systems bone marrow spleen MALT of the lung and the lung tissue itself from the action radiation and other toxicants that lead to the accumulation of ROS The protocol for Phase II study ldquo The efficacy of physiotherapy intervention by Wave Device in treatment and preventing of radiation induced diseases rdquo is proposed All experimental work was performed according to the protocols that have been approved by the Committee on Bioethics at IEPOR
本文介绍了利用波浪装置通过减少活性氧自由基来预防和治疗辐射诱导疾病的特点和建议。从实验动物中获得的信息表明,波浪装置在减少大鼠活性氧、保护辐射敏感细胞和系统、骨髓、脾脏、肺部和肺组织本身免受辐射和其他有毒物质的作用方面具有积极作用II期研究方案提出了Wave Device物理治疗干预在治疗和预防辐射诱导疾病中的疗效,所有实验工作均按照IEPOR生物伦理委员会批准的方案进行
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引用次数: 0
A study on the response of 2D ion chamber array detector for VMAT delivery 二维离子室阵列探测器对VMAT发射的响应研究
Pub Date : 2018-08-07 DOI: 10.15406/IJRRT.2018.05.00172
S Kumar, A. George
Purpose This study aims to evaluate the response of D ion chamber array detector for VMAT delivery Methods D array ionization chamber equipped with ionization chambers uniformly arranged in a times matrix with an active times cm was used for the study An Octagonal shaped phantom Octavius Phantom with a central cavity is used to insert the D ion chamber array All measurements were done with a linear accelerator The plans that are already being verified has been selected for studying the response of D array Results This study shows that the response of the D array gets reduced as compared to early quality assured plans Plans were analyzed using the Gamma analysis method The results show a variation up to comparing earlier plans Conclusion The response of the D array gets reduced while compared with earlier quality assured plans
目的本研究旨在评估D电离室阵列探测器的响应VMAT交付方法D数组电离室配备电离室统一安排在乘以矩阵与一个活跃的厘米被用于研究一个八角形的屋大维的幻影中央腔用于插入数组维电离室测量都是用一个线性加速器的计划已经被证实已被选为研究响应结果本研究表明,与早期的质量保证方案相比,D阵列的响应降低了,使用Gamma分析方法对方案进行了分析,结果表明与早期的质量保证方案相比,D阵列的响应降低了
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引用次数: 1
Estimation of foetal radiation dose in a comparative study of pelvimetry with conventional radiography and different computer tomography methods 骨盆测量与常规x线摄影及不同计算机断层摄影方法的比较研究
Pub Date : 2018-07-30 DOI: 10.15406/IJRRT.2018.05.00171
Erika Phexell, M. Söderberg, A. Bolejko
Introduction Conventional radiography and computed tomography CT can result in different radiation doses to the foetus when pelvimetry needs to be performed before childbirth New techniques in diagnostic imaging provide the basis for the optimization of radiation dose and create opportunities for higher measurement accuracy The purpose of the study was to estimate the radiation dose to the foetus from pelvimetry performed using conventional radiography compared to different CT methods namely the topogram method cross sectional method short spiral method standard spiral method and flash spiral method Methods An anthropomorphic phantom and thermoluminescent dosemeters TLD were used for the dose measurements Bags with sodium chloride were placed on top of the phantom rsquo s abdomen and were used to simulate the last month of pregnancy The foetal radiation dose was equated to the absorbed energy to the TLDs placed at the area of the birth canal uterus Results Themean absorbed dose to the foetus was measured with conventional radiographic technique to mGy The mean absorbed dose to the foetus with the various CT methods resulted in mGy topogram mGy cross sectional mGy short spiral mGy standard spiral and mGy flash spiral Conclusion Although the absorbed dose to the foetus was higher in the CT pelvimetry methods the dose levels are low The CT spiral methods allowed adjustments in multiplane image reconstructions which could increase measurement accuracy However further studies are needed to investigate different CT pelvimetry methods in relation to measurement accuracy
当需要在产前进行骨盆测量时,传统的x线摄影和计算机断层扫描CT会导致胎儿受到不同的辐射剂量。诊断成像的新技术为优化辐射剂量提供了基础,并为更高的测量精度创造了机会。本研究的目的是估计使用传统x线摄影进行骨盆测量对胎儿的辐射剂量,并与不同的CT方法进行比较topogram横断法短螺旋方法标准螺旋法和flash螺旋方法方法一个拟人化的幻影和热释光的放射量测定器TLD剂量用于测量包与氯化钠被放置在幻影去腹部和被用来模拟上个月怀孕的胎儿被等同于吸收辐射能量TLD放置在产道的面积子宫结果Themean吸收剂量不同CT测量方法对胎儿的平均吸收剂量有不同程度的变化,分别为mGy地面图、mGy横截面图、mGy短螺旋图、mGy标准螺旋图和mGy闪光螺旋图。结论CT骨盆测量方法对胎儿的吸收剂量较高,但剂量水平较低,CT螺旋法可在多平面图像重建中进行调整,提高测量精度,但还有待进一步研究需要研究不同的CT骨盆测量方法与测量精度的关系
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引用次数: 5
Primary hyperaldosteronism in the composition of arterial hypertension: diagnosis and treatment 原发性高醛固酮血症与动脉高血压的诊断和治疗
Pub Date : 2018-07-23 DOI: 10.15406/IJRRT.2018.5.00169
Z. Y. Xalimova, Ga Dalimova, Y. Urmanova, N. Rikhsieva, Safarova, A. Gumarova, Gm Jabborova, M. Kim
Primary hyperaldosteronism is a rare form of symptomatic arterial hypertension (AH), it is a clinical syndrome that develops as a result of excessive production of aldosterone by the glomerular zone of the adrenal cortex, in which the secretion of aldosterone is completely or partially autonomous towards to the renin-angiotensin system, which causes the development of low-renin arterial hypertension (AH).
原发性高醛固酮增多症是一种罕见的有症状的动脉高血压(AH),它是一种临床综合征,由于肾上腺皮质的肾小球区醛固酮过量产生,醛固酮的分泌完全或部分自主地向肾素-血管紧张素系统分泌,从而导致低肾素动脉高血压(AH)的发展。
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引用次数: 0
A radiation oncology approach for using definitive radiotherapy with volumetric modulated arc therapy (VMAT) for skin field cancerisation (SFC) 放射肿瘤学方法对皮肤野癌变(SFC)使用体积调制电弧治疗(VMAT)的明确放疗
Pub Date : 2018-07-16 DOI: 10.15406/IJRRT.2018.05.00168
G. Fogarty, David RH Christie, A. Kamiński, A. Potter
Patients with long histories of chronic ultraviolet radiation exposure can suffer from skin field cancerisation SFC They can have poor oncological outcomes and quality of life QoL with itch flaking skin and suboptimal cosmesis Current treatments have high rates of treatment failure and non compliance Definitive radiotherapy RT with volumetric modulated arc therapy VMAT has been proposed as a possible treatment modality in this clinical setting This article provides a theoretical background to assist radiation oncologists ROs to implement this technique in their skin cancer practice The article covers the importance of the relationship between the skin physician and the RO how to best understand the patient with SFC patient assessment preparation for RT and RT planning and treatment The article also highlights the difficulty in measuring toxicities with the currently available tools and suggests future research options for affected patients Clinical studies to further refine the use of RT in patients with SFC are warranted
长期慢性紫外线照射的患者可能会出现皮肤野癌变(SFC),他们可能有较差的肿瘤预后和生活质量(QoL),皮肤瘙痒剥落和美容效果不佳。目前的治疗方法治疗失败率和不依从性很高,明确放疗RT结合体积调节电弧治疗(VMAT)已被提出作为一种可能的治疗方式协助放射肿瘤学家RO在他们的皮肤癌实践中实施这项技术。文章涵盖了皮肤医生和RO之间关系的重要性,如何最好地了解SFC患者的患者评估,准备RT和RT计划和治疗。文章还强调了使用现有工具测量毒性的困难,并为受影响的患者提出了未来的研究选择临床研究,以进一步完善使用SFC患者的RT治疗是必要的
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引用次数: 6
Non-operative treatment of morton’s interdigital neuroma with a foot orthosis 足部矫形器非手术治疗莫顿指间神经瘤
Pub Date : 2018-07-05 DOI: 10.15406/IJRRT.2018.05.00165
Lorenzo Brognara, Simone Santarini
Morton rsquo s neuroma is a frequent cause of forefoot sharp pain associated with a burning sensation and paresthesias Histologic findings of Morton s neuroma include perineural fibrosis of intermetatarsal nerve Conservative measures are indicated to relieve symptoms and can also increase the gait parameters that require good function of the forefoot For this study we chose to use a drop shaped metatarsal pad and a silicone orthosis which are both found to be beneficial in treatment of Morton rsquo s Neuroma The ultrasound image showed the disappearance of the anechogenous irregular area between third and fourth metatarsal head of left foot We have demonstrated that the use of a ultrasound machine is a feasible alternative to conventional processes to validate the foot orthoses The importance and originality of this study is to show a new effectiveness evaluation approach for the orthotic insoles Patient reported benefit from foot orthosis both during sport activity and in everyday life
莫顿去年代神经瘤是一种常见的前脚剧烈的疼痛原因与烧灼感和感觉异常莫顿年代神经瘤的组织学研究结果包括神经周的纤维化intermetatarsal神经保守措施表示缓解症状,还可以增加的步态参数,需要好的功能前脚在这项研究中,我们选择使用下降形状的跖骨垫,硅胶矫正法都是发现在治疗莫顿是有益的超声图像显示左脚第三和第四跖骨头之间的无回声不规则区域消失。我们已经证明,使用超声机器是一种可行的替代传统方法来验证足部矫形器。本研究的重要性和独创性在于展示了一种新的矫形鞋垫有效性评估方法。患者报告在体育活动和日常生活中都受益于足部矫形器生活
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引用次数: 0
A prospective study to evaluate the role of curcumin in treatment of locally advanced carcinoma of cervix 姜黄素治疗局部晚期宫颈癌的前瞻性研究
Pub Date : 2018-07-05 DOI: 10.15406/IJRRT.2018.05.00167
N. Bansal, A. Chauhan, P. Kaur, A. Basu, A. Khurana, Y. Verma, M. Chauhan
Objectives The present study is conducted to determine the role of curcumin alongwith chemoradiation in the management of locally advanced carcinoma cervix in terms of toxicity tumor response and survival rates Methods Patients were enrolled into study from Jan to Jan The patients were randomized into two groups group I and group II of patients each All patients were planned for external beam radiotherapy EBRT to total dose of Gy fractions weeks with concomitant cisplatin mg m IV weekly HDR brachytherapy with fractions of Gy each was given weekly after completion of EBRT Curcumin gm day was given orally to group I patients from the start of EBRT till the completion of brachytherapy Results The baseline patients rsquo characteristics were matched in the two groups The median follow up was of two years After the completion of treatment complete tumor response was seen in and patients in group I and II respectively Overall survival and disease free survival rates were in group I and in group II respectively The findings were not statistically significant Grade skin reactions were seen in and of the patients in group I and group II respectively Acute mucosal toxicity of grade was seen in and of patients in group I and II respectively Conclusion The significant difference was found in occurrence of severe acute radiation toxicity to skin and mucosa with comparable survival rates in the two groups i e with and without curcumin
目标本研究确定姜黄素随着放化疗的角色进行管理的局部晚期癌宫颈肿瘤的毒性反应和存活率方法患者进入研究从1月到1月的患者随机分成两组二组我和组的患者每所有患者体外放射治疗计划EBRT与伴随的Gy分数周总剂量顺铂mg m IV每周HDR近距离放射疗法的分数Gy每个被每周完成后EBRT姜黄素通用汽车一天口服组我病人从一开始EBRT直到完成近距离放射疗法的结果该基线患者特征匹配在两组中位数跟进完成后两年的完整的肿瘤治疗反应是在和病人分别在I和II组总体存活率和无病生存率在我和组I组和II组患者分别出现了皮肤级反应,I组和II组患者分别出现了皮肤级急性黏膜毒性。结论在使用和不使用姜黄素时,两组患者皮肤和粘膜严重急性辐射毒性的发生率差异有统计学意义,生存率相当
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引用次数: 0
Kikuchi fujimoto disease mimicking lymphoma detected on pet-ct imaging in a pediatric patient 在儿科患者的pet-ct成像上检测到类似淋巴瘤的菊池藤本病
Pub Date : 2018-07-05 DOI: 10.15406/IJRRT.2018.05.00166
P. Kara, Z. Koç, E. Çıtak, F. Karaman, M. Yaldız
Kikuchi Fujimoto s disease KFH which is seen more often in young Asian women than in childhood is a rare benign feature of PET CT that can be confused with malignant lymphoma due to common cervical hypermetabolic lymphadenopathy and high SUV values In this interesting case report PET CT imaging findings of a rare Kikuchi Fujimoto disease mimicking lymphoma in a pediatric patient is presented
Kikuchi Fujimoto病KFH是一种罕见的PET CT良性特征,在亚洲年轻女性中比在儿童期更常见,由于常见的颈部高代谢淋巴结病和高SUV值,可与恶性淋巴瘤混淆。在这个有趣的病例中,我们报告了一名儿科患者罕见的模仿淋巴瘤的Kikuchi Fujimoto病的PET CT成像结果
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引用次数: 0
Assessment of the dynamics of bone edema in fractures of long tubular bones in children in the process of osteoregeneration according to magnetic resonance imaging 磁共振成像评价儿童长管骨骨折在骨再生过程中的骨水肿动态
Pub Date : 2018-06-14 DOI: 10.15406/ijrrt.2018.05.00162
Tarasenko Ll, Tarasenko Ts
Children 6-10 years old very active, incautious, careless of danger this is a main care children’s traumatologist. Excessive shortcut immobilization extremity is not for all time correctly. After manual reposition and plaster immobilization MRI show wavy rise in intensity of the signal and reach the maximum values on the 20th day after the trauma with the continued its decrease. The exception is a group of children, the younger school age, who save high intensity signal during the 40-45-th days. MRI allows an estimate of the degree of expression of the trabecular edema, the development of granulation, and the development of the callus without X-ray.
6-10岁的孩子很好动,不小心,不小心有危险,这是儿童创伤科医生主要照顾的。过度捷径固定四肢并不总是正确的。手动复位和石膏固定后,MRI信号呈波浪形上升,在外伤后第20天达到最大值,随后继续下降。唯一的例外是一群学龄较小的儿童,他们在40-45天内保存高强度信号。MRI可以在没有x线的情况下估计小梁水肿的表达程度、肉芽的发展和骨痂的发展。
{"title":"Assessment of the dynamics of bone edema in fractures of long tubular bones in children in the process of osteoregeneration according to magnetic resonance imaging","authors":"Tarasenko Ll, Tarasenko Ts","doi":"10.15406/ijrrt.2018.05.00162","DOIUrl":"https://doi.org/10.15406/ijrrt.2018.05.00162","url":null,"abstract":"Children 6-10 years old very active, incautious, careless of danger this is a main care children’s traumatologist. Excessive shortcut immobilization extremity is not for all time correctly. After manual reposition and plaster immobilization MRI show wavy rise in intensity of the signal and reach the maximum values on the 20th day after the trauma with the continued its decrease. The exception is a group of children, the younger school age, who save high intensity signal during the 40-45-th days. MRI allows an estimate of the degree of expression of the trabecular edema, the development of granulation, and the development of the callus without X-ray.","PeriodicalId":214028,"journal":{"name":"International Journal of Radiology & Radiation Therapy","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131552822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Radiology & Radiation Therapy
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