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Video-electroencephalography Monitoring and Cerebral Imaging are Mandatory in Patients with Functional Seizures. 功能性癫痫发作患者必须接受视频脑电图监测和脑成像。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 Epub Date: 2024-01-15 DOI: 10.4103/sjmms.sjmms_413_23
Josef Finsterer
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引用次数: 0
Thrombolytic Therapy in Strokes: A Retrospective Clinical Data Analysis of 40 Patients in a 7-Year Period: The Experience of a Greek Internal Medicine Department 脑卒中的溶栓治疗:对7年40例患者的回顾性临床数据分析:希腊内科的经验
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-11-06 DOI: 10.36348/sjm.2023.v08i11.001
Athina Myrou, Anthoula Tsolaki, Thomas Tegos, Christos Savopoulos
Stroke is one of the main causes of mortality and disability in developed countries. In acute ischemic stroke, the standard treatment is recombinant tissue plasminogen activator (rt-PA). The benefits of the treatment depend on the time of administration, the earlier it is administered, the greater its benefit. There are limited studies on the retrospective outcome of thrombolytic therapy in patients with acute ischemic stroke outside of clinical trials. The present retrospective study aimed to analyze the clinical data of 40 patients over 7 years who were hospitalized with acute ischemic stroke at the AHEPA University Hospital in Greece. From January 2013 to December 2020, 40 patients with acute ischemic stroke were admitted and treated. Computed tomography (CT) was performed at 24 h after thrombolytic treatment or earlier in case of neurological worsening. The hospital had 3 months follow-up at the stroke clinic and data consisting of the National Institute of Health Stroke Scale (NIHSS), functional outcome assessed by modified Rankin Scale (mRS) and mortality were reviewed in the medical records from the stroke clinic. The clinical outcome of functional independence defined by the modified Rankin Scale (mRS) ≤ 2 at 3 months was evaluated. Safety outcomes were in-hospital mortality, mortality at 3 months, and symptomatic intracerebral hemorrhage (sICH) defined by the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST) criteria. The main finding of the present study, that there was an overall reduction in the NIHSS scale after thrombolysis, proves that the patients showed improvement after performing thrombolysis. Consequently, from the total of 40 thrombolysis performed at the clinic, it can be concluded that most patients had a good outcome.
中风是发达国家造成死亡和残疾的主要原因之一。急性缺血性卒中的标准治疗是重组组织型纤溶酶原激活剂(rt-PA)。治疗的好处取决于给药的时间,越早给药,好处越大。在临床试验之外,关于急性缺血性卒中患者溶栓治疗的回顾性结果的研究有限。本回顾性研究旨在分析在希腊AHEPA大学医院住院的40例7年以上急性缺血性脑卒中患者的临床资料。2013年1月至2020年12月共收治急性缺血性脑卒中患者40例。在溶栓治疗后24小时或在神经系统恶化的情况下更早进行计算机断层扫描(CT)。本院卒中门诊随访3个月,资料包括国立卫生研究院卒中量表(NIHSS)、修正Rankin量表(mRS)评估的功能结局和卒中门诊病死率。3个月时以改良Rankin量表(mRS)≤2定义的功能独立性临床结局进行评估。安全性结果是住院死亡率、3个月死亡率和卒中监测研究(sit - most)中安全实施溶栓标准定义的症状性脑出血(sICH)。本研究的主要发现是溶栓后NIHSS量表整体下降,证明溶栓后患者病情有所改善。因此,从临床共进行的40例溶栓手术中,可以得出结论,大多数患者预后良好。
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引用次数: 0
Case Report of Numb Chin Syndrome (NCS) in Sickle Cell Disease (SCD) 镰状细胞病(SCD)伴麻木颏综合征1例报告
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-19 DOI: 10.36348/sjm.2023.v08i10.005
Omar Basubrain
Numb chin syndrome is a rare presentation due to injury to mental nerve characterized by numbness, hypoesthesia, and paresthesia. This syndrome is mostly presented with dental interventions, traumatic injuries, or malignant pathologies. We report a unique case of a 20-year-old male diagnosed with sickle cell disease presented with loss of sensation over right chin area secondary to the vaso-occlusive crisis. This case depicts a complex relationship between neurological complications and hemoglobinopathies of SCD.
颏麻木综合征是一种罕见的表现,由于精神神经损伤,其特点是麻木,感觉不足,和感觉异常。这种综合征主要表现为牙科干预、创伤性损伤或恶性病变。我们报告一个独特的情况下,20岁的男性诊断为镰状细胞病提出感觉丧失在右下巴区域继发血管闭塞危机。本病例描述了SCD的神经并发症和血红蛋白病之间的复杂关系。
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引用次数: 0
Disease X: Are we Ready to Tackle the Next Global Pandemic Again? X疾病:我们准备好再次应对下一次全球大流行了吗?
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-17 DOI: 10.36348/sjm.2023.v08i10.004
Rahul shil, Shreyasee Das
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引用次数: 0
Health Care Associated Infective Endocarditis in Hemodialysis: More than Just Valve Infection- A Case Series 血液透析中保健相关的感染性心内膜炎:不仅仅是瓣膜感染-一个病例系列
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-15 DOI: 10.36348/sjm.2023.v08i10.003
Devanath, D, Prashant G. Kedlaya, Jairam, A, Renuka Renuka, Shashank S. Dhareshwar
Cardiovascular diseases and infections are the two main causes of mortality in Hemodialysis patients [1, 6]. Health care associated infective endocarditis among them carries higher morbidity and mortality. The following is a case series of 3 Enterococcal endocarditis in HD patients and our experience in the management.
心血管疾病和感染是导致血液透析患者死亡的两大主要原因[1,6]。其中与卫生保健相关的感染性心内膜炎具有较高的发病率和死亡率。以下是3例HD患者肠球菌性心内膜炎的病例系列和我们的治疗经验。
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引用次数: 0
Unusual Presentation of Rhabdomyolysis & Acute Kidney Injury in a Young Patient with Associated Pancreatitis of Un-Known Etiology 横纹肌溶解症的特殊表现急性肾损伤的年轻患者合并不明原因的胰腺炎
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-15 DOI: 10.36348/sjm.2023.v08i10.002
Arif Noormohammed Thekiya, Ahmed Salah Eid, Aalya Mohamed, Magdoleen Ibrahim A. Sabbah, Ali Aziz, Waleed H. Flayyih, Sameh Mohamed, Rehan Ahmed, Alaa Bbiker M. Ahmed
A case of 41-year-old patient presented with left lower leg cellulitis, laboratory investigations showed elevated CK levels of more than 193000 U/L, high pancreatic enzymes level namely amylase & lipase, significant electrolyte and acid base abnormalities. Diagnosis of Rhabdomyolysis made based on CK level results in acute pancreatitis. This patient developed acute renal failure with all above in mind, he stayed inpatient for 19 days. The purpose of this case report is to highlight the unusually high CK with unusual association of acute pancreatitis leading to rhabdo¬myolysis and the associated morbidity.
1例41岁左下肢蜂窝组织炎患者,实验室检查显示CK升高193000 U/L以上,胰酶即淀粉酶高;脂肪酶,明显的电解质和酸碱异常。基于CK水平诊断急性胰腺炎横纹肌溶解。考虑到上述情况,该患者发生急性肾衰竭,住院19天。本病例报告的目的是强调异常高CK与急性胰腺炎导致横纹肌溶解和相关发病率的异常关联。
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引用次数: 0
Hiccups of Neurological Origin: A Case Report 神经性打嗝1例报告
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-11 DOI: 10.36348/sjm.2023.v08i10.001
Y. Aroudam, N. Benzoubeir, I. Errabih, H. El Bacha
Hiccups are most often benign and short-lived, but they can also be persistent (> 48h) or even refractory (> 1 month). In these cases, it impairs qualitý of life and can have serious health consequences. We report the case of a patient who consulted for chronic hiccups with absences and in whom the neurological origin was confirmed on brain MRI.
打嗝通常是良性和短暂的,但也可能是持续性的(>48h)甚至耐火(>1个月)。在这些情况下,它会损害qualitý的生命,并可能产生严重的健康后果。我们报告的情况下,病人谁咨询慢性打嗝缺席,并在脑MRI证实了神经起源。
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引用次数: 0
Use of Artificial Pancreas in the Management of Diabetes Mellitus: A Bibliometric Study. 人工胰腺在糖尿病治疗中的应用:文献计量学研究。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-01 Epub Date: 2023-10-06 DOI: 10.4103/sjmms.sjmms_12_23
Eileen Marin-Garaundo, Rosario La Torre-Beteta, Arnaldo Munive-Degregori, Juan Alvitez, John Barja-Ore, Frank Mayta-Tovalino

Objectives: To describe the trends and characteristics of the worldwide scientific production on the use of artificial pancreas (AP) in the management of diabetes mellitus (DM).

Materials and methods: Scientific papers published between 2017 and 2022 were retrieved from the Scopus database using relevant keywords. Only original articles, reviews, and short surveys were included. The metadata were exported to the SciVal software for retrieving quantitative data and the main characteristics such as journals, authors, institutions, journal metrics by quartiles, subcategories, and collaborative networks were extracted.

Results: A total of 642 articles were included after applying the inclusion/exclusion criteria: original articles, 489; reviews, 151; and short surveys, 2. The most common type of collaboration was at the national level (38.3%; citations per publication: 22.3; field-weighted citation index [FWCI]: 2.2) followed by international collaboration (29.4%; citations per publication: 19.6; FWCI: 1.94). More than 70% of articles in each year were published in journals listed in Q1. Two journals, Diabetes Technology and Therapeutics and Journal of Diabetes Science and Technology, accounted for about 22% of all publications. Six of the top 10 universities were from the United States, with The University of Virginia having the most publications (n = 54; 59 authors; citations per publication: 38.4; FWCI: 3.73).

Conclusions: The findings of this study highlight that most research on this topic is published in high-quality journals and has a good citation impact. Notably, most research has been conducted in developed countries, thereby indicating the need for research efforts in this field from developing countries.

目的:介绍世界范围内人工胰腺(AP)在糖尿病(DM)治疗中的发展趋势和特点。材料与方法:使用相关关键词从Scopus数据库检索2017 - 2022年间发表的科学论文。仅包括原创文章、评论和简短调查。将元数据导出到SciVal软件中用于检索定量数据,提取主要特征,如期刊、作者、机构、按四分位数划分的期刊指标、子类别和协作网络。结果:应用纳入/排除标准,共纳入642篇文献:原始文献489篇;评论,151;和简短的调查,2。最常见的合作类型是在国家一级(38.3%;出版物引用次数:22.3次;领域加权引文索引[FWCI]: 2.2),其次是国际合作(29.4%;出版物引用次数:19.6次;FWCI: 1.94)。每年超过70%的文章发表在Q1所列期刊上。《糖尿病技术与治疗》和《糖尿病科学与技术杂志》这两种期刊约占所有出版物的22%。前10所大学中有6所来自美国,其中弗吉尼亚大学发表论文最多(n = 54;59岁的作者;出版物引用数:38.4;FWCI: 3.73)。结论:本研究结果表明,该主题的研究大多发表在高质量期刊上,具有良好的被引影响。值得注意的是,大多数研究都是在发达国家进行的,从而表明发展中国家需要在这一领域进行研究努力。
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引用次数: 0
Breastfeeding Self-efficacy is Inversely Associated with Postpartum Depression: Findings from a Tertiary Hospital in Saudi Arabia. 母乳喂养自我效能与产后抑郁呈负相关:来自沙特阿拉伯一家三级医院的研究结果
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-01 Epub Date: 2023-10-06 DOI: 10.4103/sjmms.sjmms_601_22
Razana Saleh Baeisa, Nashwa Fahed Aldardeir, Manar Thamer Alsulami, Ahlam Hamdi Alsulami, Jana Hamed Al-Sharif, Taif Ali Alshahrany, Waleed Ahmed Alghamdi

Background: High breastfeeding self-efficacy is linked with lower rates of postpartum depression. No study from Saudi Arabia has previously assessed the relation between breastfeeding self-efficacy and postpartum depression.

Objective: To determine the correlation between breastfeeding self-efficacy and postpartum depression in a cohort from Saudi Arabia.

Materials and methods: This cross-sectional study included mothers who had given birth between February to June 2022 at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, and were between 2 weeks and 3 months postpartum. Data were collected using a self-administered questionnaire comprising the following three sections: sociodemographic characteristics, Edinburgh Postpartum Depression Scale (EPDS), and Breastfeeding Self Efficacy Scale-Short Form (BSES-SF).

Results: A total of 257 participants completed the questionnaire, with most aged 25-34 years (59.1%). The prevalence of postpartum depression was 25.3%, and it was significantly associated with lack of support from the husband and family during pregnancy (for both, P < 0.001), history of violence (P < 0.001), family history of depression (P = 0.045), complications during pregnancy (P = 0.004), and multiple pregnancies (P = 0.004). The mean score on the BSES-SF was 47.4, and participants who scored above the mean had significantly lower rates of postpartum depression (P = 0.003). In addition, an inverse relation was noted between BSES-SF and postpartum depression scores (r = -0.297): when the scores of BSES-SF increased, the scores of postpartum depression decreased.

Conclusion: The rate of postpartum depression was high in Jeddah, Saudi Arabia; nonetheless, positive breastfeeding self-efficacy was found to be correlated with lower rates of postpartum depression. These findings indicate the need for careful screening of patients at risk of postpartum depression and for providing breastfeeding support/knowledge, both in the antenatal and postpartum periods.

背景:高母乳喂养自我效能感与产后抑郁症发生率较低有关。沙特阿拉伯此前没有研究评估母乳喂养自我效能和产后抑郁之间的关系。目的:探讨沙特阿拉伯母乳喂养自我效能感与产后抑郁的相关性。材料和方法:本横断面研究纳入了2022年2月至6月在沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院分娩,产后2周到3个月的母亲。数据采用自填问卷收集,包括以下三个部分:社会人口学特征、爱丁堡产后抑郁量表(EPDS)和母乳喂养自我效能量表-简表(BSES-SF)。结果:共完成问卷257人,年龄以25-34岁居多(59.1%)。产后抑郁患病率为25.3%,与孕期缺乏丈夫和家庭支持(P < 0.001)、有暴力史(P < 0.001)、有抑郁家族史(P = 0.045)、孕期并发症(P = 0.004)、多胎妊娠(P = 0.004)显著相关。BSES-SF的平均得分为47.4分,得分高于平均值的参与者产后抑郁的发生率显著降低(P = 0.003)。此外,BSES-SF与产后抑郁得分呈负相关(r = -0.297): BSES-SF得分越高,产后抑郁得分越低。结论:沙特阿拉伯吉达地区产后抑郁症发生率较高;然而,积极的母乳喂养自我效能感被发现与产后抑郁症的发生率较低相关。这些发现表明,需要仔细筛查有产后抑郁症风险的患者,并在产前和产后提供母乳喂养支持/知识。
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引用次数: 0
Prevalence and Risk Factors of Cytomegalovirus Colitis in Inflammatory Bowel Disease Patients in Riyadh, Saudi Arabia: A Tertiary Center Experience. 沙特阿拉伯利雅得炎性肠病患者巨细胞病毒结肠炎的患病率和危险因素:三级中心经验。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-01 Epub Date: 2023-10-06 DOI: 10.4103/sjmms.sjmms_175_23
Yazeed Alotaibi, Abed AlLehibi, Abdullah Almtawa, Nawaf Alotaibi, Adel Alghamdi, Saad Alrajhi, Adel AlQutub, Ahmad AlEid, Abdulrhman Alamr, Bashaar Al Ibrahim, Mohammed Alahmari, Hussam Alhamidi, Shameem Ahmad, Fouad Alshammari, Fahad Almotawa, Youssef Altannir, Ahmed Alghamdi

Background: Patients with inflammatory bowel disease (IBD) are at a higher risk of cytomegalovirus (CMV) colitis because of their immunocompromised status. There are no studies from Saudi Arabia regarding the prevalence of CMV colitis in patients with IBD.

Objective: To determine the prevalence, characteristics, and risk factors of CMV colitis in patients with IBD in Riyadh, Saudi Arabia.

Materials and methods: This retrospective study included patients with a confirmed diagnosis of IBD (aged 14-75 years) who were followed up at King Fahad Medical City, a referral care center in Riyadh, between January 2016 and December 2021; patients with indeterminate colitis or incomplete medical records were excluded.

Results: A total of 341 patients with IBD were included, of which 236 (72.2%) had Crohn's disease (CD) and 105 (27.8%) had ulcerative colitis (UC). Qualitative CMV PCR was done for 192 patients (60 UC and 132 CD patients), of which 14 patients were positive for CMV colitis (7.3%), and all positive CMV colitis cases were among UC patients (23.3%). However, the hematoxylin and eosin (H and E) stain and immunohistochemistry were negative for all patients. Most patients with CMV colitis were on steroids (71.4%), had at least one flare-up (64.3%), and were on biologic treatment (71.4%). Significant predictors of CMV colitis were hemoglobin (OR: 0.7; 95% CI: 0.51-0.96), albumin (OR: 0.88; 95% CI: 0.78-0.98), and C-reactive protein (OR: 1.03; 95% CI: 1.01-1.06) levels.

Conclusion: This study found that the prevalence of CMV colitis was 7.3% among patients with IBD, and no case was diagnosed in patients with CD. In addition, as all cases diagnosed using qualitative CMV PCR were negative on H and E stain and immunohistochemistry, there is need for large-scale studies to improve the diagnosis of CMV colitis.

背景:炎症性肠病(IBD)患者由于免疫功能低下,发生巨细胞病毒(CMV)结肠炎的风险较高。没有来自沙特阿拉伯的关于IBD患者巨细胞病毒结肠炎患病率的研究。目的:了解沙特阿拉伯利雅得IBD患者巨细胞病毒结肠炎的患病率、特征和危险因素。材料和方法:本回顾性研究纳入了2016年1月至2021年12月期间在利雅得转诊护理中心法赫德国王医疗城随访的确诊IBD患者(14-75岁);不确定结肠炎或医疗记录不完整的患者被排除在外。结果:共纳入341例IBD患者,其中克罗恩病236例(72.2%),溃疡性结肠炎105例(27.8%)。对192例患者(60例UC, 132例CD)进行定性CMV PCR检测,其中14例CMV结肠炎阳性(7.3%),所有CMV结肠炎阳性病例均为UC患者(23.3%)。然而,所有患者的苏木精和伊红(H和E)染色和免疫组织化学均为阴性。大多数CMV结肠炎患者接受类固醇治疗(71.4%),至少有一次急性发作(64.3%),并接受生物治疗(71.4%)。CMV结肠炎的重要预测因子是血红蛋白(OR: 0.7;95% CI: 0.51-0.96),白蛋白(OR: 0.88;95% CI: 0.78-0.98)和c反应蛋白(OR: 1.03;95% CI: 1.01-1.06)水平。结论:本研究发现,IBD患者中巨细胞病毒结肠炎的患病率为7.3%,而CD患者中没有确诊病例。此外,定性CMV PCR诊断的病例均为H、E染色和免疫组化阴性,需要进行大规模研究以提高巨细胞病毒结肠炎的诊断水平。
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引用次数: 0
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Saudi Journal of Medicine & Medical Sciences
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