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Spontaneous Bladder Wall Rupture Due to Emphysematous Cystitis in a Diabetic Patient: A Case Report 糖尿病患者气肿性膀胱炎导致膀胱壁自发性破裂:病例报告
Pub Date : 2024-05-11 DOI: 10.36347/sjmcr.2024.v12i05.019
H. Loukili, M. Jaouaher, Y. Bouktib, A. E. Hajjami, B. Boutakioute, M. Idrissi, N. E. Ganouni
Spontaneous rupture of the urinary bladder (SRUB) secondary to emphysematous. Cystitis (EC) in diabetic patients is extremely rare. Emphysematous cystitis is a relatively rare disease entity characterized by intramural and/or intraluminal bladder gas best depicted by cross-sectional imaging. Its disease mechanism is not well understood. Case report: A 61-year-old diabetic woman presented to the emergency department with diffuse abdominal pain and hematuria of tree hours duration. Physical examination revealed generalized abdominal tenderness. Multi-slice abdominal and pelvic CT scans showed parietal pneumatosis of bladder and communicating continuity solutions with a pre-vesical collection (extravasation of PDC into the collection). After proper resuscitation, the patient was transferred to the operating room for exploratory laparotomy. A thickness bladder rupture was noted, which was repaired. Conclusions: SRUB in patients with poorly controlled diabetes and EC is highlighted in this case study. Urinary bladder rupture secondary to EC should be considered when a diabetic patient with a history of urinary symptoms presents with an acute onset of abdominal pain. Uneventful recovery from SRUB is dependent on early diagnosis and treatment.
继发于气肿性膀胱炎(EC)的膀胱自发性破裂(SRUB)在糖尿病患者中极为罕见。糖尿病患者的膀胱炎(EC)极为罕见。气肿性膀胱炎是一种相对罕见的疾病,其特点是膀胱壁内和/或腔内气体,通过横断面成像可以得到最好的描述。其发病机制尚不十分清楚。病例报告:一名 61 岁的糖尿病妇女因持续数小时的弥漫性腹痛和血尿到急诊科就诊。体格检查显示其腹部普遍压痛。多层腹部和盆腔 CT 扫描显示膀胱顶充气和沟通连续性溶液,并伴有膀胱前积血(PDC 外渗到积血中)。经过适当抢救后,患者被转移到手术室进行探查性开腹手术。发现膀胱厚度破裂,并进行了修补。结论本病例研究强调了控制不佳的糖尿病合并尿毒症患者的膀胱破裂。当有泌尿系统症状史的糖尿病患者出现急性腹痛时,应考虑继发于 EC 的膀胱破裂。膀胱破裂后能否顺利康复取决于早期诊断和治疗。
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引用次数: 0
Non-Hodgkin Lymphoma of the Breast: Localization Exceptional to Know, Case Study and Literature Review 乳腺非霍奇金淋巴瘤:异常定位须知、病例研究和文献综述
Pub Date : 2024-05-11 DOI: 10.36347/sjmcr.2024.v12i05.017
H. Loukili, S. Outaghyame, C. Ahmanna, B. Zouita, D. Basraoui, H. Jalal
The mammary gland may be the site of a primary lymphoma or be invaded Secondary lymphoma of another organ. Involvement is usually unilatéral, more rarely bilatéral; primary or secondary, virtually the same varieties of lymphoma are observed. Most are B type lymphomas. Imaging is based on mammography and ultrasound, and more recently on MRI. Surgical removal is not indicated in the treatment of these lymphomas, which is essentially based on chemotherapy and immunotherapy.
乳腺可能是原发性淋巴瘤的发病部位,也可能是继发于其他器官的淋巴瘤。通常是单侧受累,双侧受累的情况更为罕见;无论是原发性还是继发性,所见的淋巴瘤种类几乎相同。大多数为 B 型淋巴瘤。影像学检查以乳腺 X 射线照相术和超声波检查为基础,最近还增加了核磁共振成像检查。这些淋巴瘤的治疗基本上以化疗和免疫治疗为主,手术切除并不适用。
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引用次数: 0
Persistent Abdominal Pain with an Uncommon Presentation of Multiple Myeloma: A Case Study 多发性骨髓瘤罕见表现的持续性腹痛:病例研究
Pub Date : 2024-05-11 DOI: 10.36347/sjmcr.2024.v12i05.015
Bounouar Ibtissam, Boumaazi Hiba, ElManjra Chama, Nacir Oussama, Lairani Fatima Ezzahra, AitErrami Adil, Sayagh Sanae, Oubaha Sophia, Samlani Zouhour, Krati Khadija
Multiple myeloma (MM) is a widespread malignant condition characterized by the proliferation of transformed plasma cells in the bone marrow, disrupting its normal functions and infiltrating adjacent bone tissues. While typically confined to the bone marrow, in rare instances, patients may develop extramedullary disease. In these uncommon scenarios, the involvement of lymph nodes poses a diagnostic challenge for practitioners in their daily routines. This report details the case of a 49-year-old male experiencing chronic abdominal pain. A computed tomography (CT) scan revealed enlargement of retroperitoneal and mesenteric lymph nodes. Biopsies confirmed a plasma cell infiltrate positive for CD138 and kappa light chain, leading to the diagnosis of multiple myeloma with extramedullary localization in lymph nodes. Our case underscores the rare presentation of extramedullary involvement in multiple myeloma, characterized by an atypical clinical manifestation.
多发性骨髓瘤(MM)是一种广泛存在的恶性疾病,其特点是转化的浆细胞在骨髓中增殖,破坏骨髓的正常功能并浸润邻近的骨组织。虽然骨髓瘤通常局限于骨髓,但在极少数情况下,患者可能会出现髓外疾病。在这些不常见的情况下,淋巴结受累会给医生的日常诊断带来挑战。本报告详述了一名 49 岁男性的慢性腹痛病例。计算机断层扫描(CT)显示腹膜后和肠系膜淋巴结肿大。活检证实浆细胞浸润,CD138 和 kappa 轻链阳性,诊断为淋巴结髓外定位的多发性骨髓瘤。我们的病例强调了多发性骨髓瘤髓外受累的罕见表现,其特点是临床表现不典型。
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引用次数: 0
A Rare Case of an Isolated Intra-Thoracic Meningocele: Case Report and Review of the Literature 一例罕见的孤立性胸膜内疝病例:病例报告和文献综述
Pub Date : 2024-05-11 DOI: 10.36347/sjmcr.2024.v12i05.016
H. Loukili, S. Outaghyame, C. Ahmanna, B. Zouita, D. Basraoui, H. Jalal
A spinal meningocele is a saccular protrusion of the meninges through a dilated intervertebral foramen or a bony defect of the vertebral column. Intrathoracic meningocele is a rare condition. Only a few cases were related in the literature. It is usually associated with neurofibromatosis type 1. Isolated intrathoracic meningoceles without neurofibromatosis is a very rare entity few cases have been reported in the medical literature. Regardless of the treatment plan cross-sectional imaging techniques such as CT and MRI are essential not only for the diagnosis but also to determine the relationship to the surrounding structures and the exclusion of other neuromas and any skeletal deformities. Surgical excision is the treatment of choice in symptomatic patients.
脊髓脑膜囊肿是指脑膜通过扩张的椎间孔或椎体骨质缺损而形成的囊状突起。胸腔内脑膜囊肿是一种罕见病。文献中仅有几例相关病例。它通常与神经纤维瘤病 1 型有关。不伴有神经纤维瘤病的孤立性胸腔内脑膜囊肿是一种非常罕见的病症,在医学文献中鲜有报道。无论采用哪种治疗方案,CT 和 MRI 等横断面成像技术都是必不可少的,这不仅有助于诊断,还能确定与周围结构的关系,排除其他神经瘤和任何骨骼畸形。手术切除是无症状患者的首选治疗方法。
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引用次数: 0
Could Sudden Unilateral Sensorineural Hearing Loss be the Only Manifestation of COVID-19: Case Report 突发性单侧感音神经性听力损失可能是 COVID-19 的唯一表现:病例报告
Pub Date : 2024-05-11 DOI: 10.36347/sjmcr.2024.v12i05.014
N. Belhaj, R. Bencheikh, M. Benbouzid, Leila Essakalli Houssaini
Auditory neuritis associated with cochleitis has already been described in viral damage; Several mechanisms are mentioned; either indirectly by an antibody response that cross-reacts with an inner ear antigen, or directly by an invasion of the cochlear nerve or anterior labyrinth. Non-specific symptoms such as SSNHL might be the only sign to recognize COVID-19 cases. The aim of this article is to report case of 35 year old man; who presented sudden unilateral deafness as the only symptom of SARS covid 19.
在病毒性损伤中已经描述了与耳蜗炎相关的听觉神经炎;其中提到了几种发病机制:与内耳抗原交叉反应的间接抗体反应,或直接入侵耳蜗神经或前迷宫。SSNHL 等非特异性症状可能是识别 COVID-19 病例的唯一标志。本文旨在报告一例 35 岁男子的病例,该男子以突发性单侧耳聋作为 SARS COVID-19 的唯一症状。
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引用次数: 0
Celiac Disease Associated with Systemic Lupus Erythematosus: A Case Report 伴有系统性红斑狼疮的乳糜泻:病例报告
Pub Date : 2024-05-10 DOI: 10.36347/sjmcr.2024.v12i05.012
Amal El-Ouakhoumi, H. Joulal, J. Yousfi, L. Benjilali, M. Zahlane, L. Essaadouni
Background: Celiac disease (CD) is a chronic immune-mediated disorder with wide clinical spectrum. Its association with autoimmune diseases has been reported in several studies but coexistence with systemic lupus erythematosus (SLE) is rare. Case Report: We report a case of 47-year-old female who developed simultaneously symptoms of Celiac disease and systemic lupus erythematosus. Conclusion: The association of CD and SLE has been rarely reported and it may be explained by the sharing of a common pathogenic basis involving genetic susceptibility and overlap of autoantibodies.
背景:乳糜泻(Celiac disease,CD)是一种慢性免疫介导疾病,临床表现广泛。有多项研究报道了该病与自身免疫性疾病的关联,但与系统性红斑狼疮(SLE)并存的情况并不多见。病例报告:我们报告了一例同时出现乳糜泻和系统性红斑狼疮症状的 47 岁女性病例。结论乳糜泻和系统性红斑狼疮的关联很少见,这可能是因为两者有共同的致病基础,包括遗传易感性和自身抗体的重叠。
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引用次数: 0
Glomangiopericytoma of the Nasal Sinus Mimicking Dacryocoele: A Case Report and Literature Review 模仿泪囊的鼻腔鼻窦胶质细胞瘤:病例报告与文献综述
Pub Date : 2024-05-10 DOI: 10.36347/sjmcr.2024.v12i05.011
F. Chettibi, M. Matouk, T. Doudi, M. Naidji, S. Benbouzid, A. Amari, B. Kaabouche
Introduction: Glomangiopericytoma (GPC) of the nasal sinus is a rare mesenchymal tumor that can mimic various benign pathologies in this anatomical region. We report an unusual clinical case and describe the diagnostic and therapeutic challenges encountered. Case Presentation: A 62-year-old woman presented with swelling of the left inner eye angle, tearing, and ipsilateral nasal obstruction. Clinical examination and imaging initially suggested chronic dacryocystitis. A polypoid nasal sinus mass was detected on endoscopy and computed tomography. Complete excision was performed via endoscopic nasal sinus surgery. The histopathological analysis confirmed the definitive diagnosis of glomangiopericytoma. Discussion: Nasal sinus GPC is a rare tumor, typically benign, derived from perivascular cells. Its clinical presentation is nonspecific and can mimic more common pathologies. Diagnosis is based on imaging and histopathological analysis with immunohistochemistry. The treatment of choice is complete surgical excision, preferably via minimally invasive endoscopic approach. Long-term close monitoring is recommended due to the risk of local recurrence. Conclusion: This clinical case highlights the importance of considering glomangiopericytoma in the differential diagnosis of nasal sinus masses, even in cases of initial benign presentation. A multidisciplinary approach, involving imaging, surgery, and histopathological analysis, is essential for optimal management.
简介:鼻腔鼻窦间质瘤(GPC)是一种罕见的间质肿瘤,可在该解剖区域模拟各种良性病变。我们报告了一个不寻常的临床病例,并描述了诊断和治疗过程中遇到的挑战。病例介绍:一名 62 岁的妇女因左内眼角肿胀、流泪和同侧鼻腔阻塞而就诊。临床检查和影像学检查初步提示为慢性泪囊炎。内窥镜检查和计算机断层扫描发现鼻窦有息肉样肿块。通过鼻内镜鼻窦手术进行了完全切除。组织病理分析确诊为腺管细胞瘤。讨论:鼻腔鼻窦 GPC 是一种罕见的肿瘤,通常为良性,来源于血管周围细胞。其临床表现无特异性,可与更常见的病症相似。诊断依据是影像学和免疫组化组织病理学分析。首选的治疗方法是彻底手术切除,最好采用微创内窥镜方法。由于存在局部复发的风险,建议进行长期密切监测。结论:该临床病例强调了在鼻腔鼻窦肿块的鉴别诊断中考虑胶样血管瘤的重要性,即使是最初表现为良性的病例。影像学、手术和组织病理学分析等多学科方法对于优化治疗至关重要。
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引用次数: 0
Cancer Stem Cells in Breast Cancer 乳腺癌中的癌症干细胞
Pub Date : 2024-05-09 DOI: 10.36347/sjmcr.2024.v12i05.010
Hadraoui Ghita, Berkich Samir, Iharti Rokkaya, Berkaoui Mohamed, Bounid Oumayma, Igarramen Tarik, M. Darfaoui, A. Omrani, M. Khouchani
Breast cancer represents a real public health problem in Morocco with one of the highest rates of mortality. Cancer stem cells are a small subset of cells found in many types of malignancies, including breast cancer, they have a crucial role in carcinogenesis, progression, recurrences and therapeutic resistance. Our study aims to understand the characteristics of breast cancer stem cells that could explain the aggressive behavior of certain tumors, with an emphasis on CD326, as a biomarker for BCSC, hoping for new targeted therapies in the future.
在摩洛哥,乳腺癌是一个真正的公共卫生问题,是死亡率最高的癌症之一。癌症干细胞是在包括乳腺癌在内的多种恶性肿瘤中发现的一小部分细胞,它们在癌变、进展、复发和耐药性方面起着至关重要的作用。我们的研究旨在了解乳腺癌干细胞的特征,以解释某些肿瘤的侵袭行为,重点研究作为乳腺癌干细胞生物标志物的CD326,希望将来能找到新的靶向疗法。
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引用次数: 0
Dermatofibrosarcoma of Darrier and Ferrand: Recurrency Character: A Case-Report (Experience of the University Hospital Tangier-Tetouan-Al Hoceima) Darrier和Ferrand皮纤维肉瘤:复发特征:病例报告(丹吉尔-泰图安-胡塞马大学医院的经验)
Pub Date : 2024-05-09 DOI: 10.36347/sjmcr.2024.v12i05.009
Dehhaze Adil, Mai Aicha, Barij Hamza, Mahioui Mimoun, Bouazza Omar, Taybi Otmane, Daghouri Nada-Imane, Labbaci Rim, Diher Issam, Echmili Mouad, Tazi Hanae
Introduction: Dermatofibrosarcoma of Darier and Ferrand (DFSP) is a rare skin tumor characterized by its local aggressiveness and high potential. Its prognosis depends essentially on the quality of its management. Observation and Results: In this article, we report the case of a young patient treated at the Department of Plastic, Reconstructive and Aesthetic Surgery, Tangier, for a Darier and Ferrand dermatofibrosarcoma that recurred five times after surgical excision, with a 5-cm margin on the surface and a healthy anatomical barrier at depth. Coverage of the loss of substance (LOS) was performed after anatomopathological confirmation of the carcinological nature of the excision, and essentially involved skin grafting. Despite a course of radiotherapy prescribed at the 4th recurrence, a 5th rapid recurrence was noted. Discussion: The great clinical, histological and evolutionary polymorphism of this type of sarcoma results in an underestimated incidence and explains the delay in diagnosis. Recurrences are frequent, and usually local. Initial wide surgical excision is the reference treatment, and directly conditions the prognosis of DFSP. According to several studies, recurrence may depend on the quality of surgical excision, but could also be attributed to genetic or environmental factors, or to variations in the histological subtype of the sarcoma. Conclusion: Darier Ferrand is an uncommon tumor with local malignancy, whose evolutionary risk depends mainly on the quality of the initial excision. The chances of cure in the case of well performed primary surgery are significantly higher than in the case of salvage surgery. Tumor excision must the refore be wide and deep, with sacrifice of a healthy barrier at depth.
导言:达里尔和费朗皮肤纤维肉瘤(DFSP)是一种罕见的皮肤肿瘤,具有局部侵袭性和高潜伏性的特点。其预后主要取决于治疗的质量。观察和结果:本文报告了丹吉尔整形、修复和美容外科治疗的一例年轻患者的病例,该患者患有 Darier 和 Ferrand 皮纤维肉瘤,手术切除后复发 5 次,表面边缘 5 厘米,深部有健康的解剖屏障。在解剖病理证实切除术具有癌变性质后,对实质缺失(LOS)进行了覆盖,主要包括植皮。尽管在第 4 次复发时进行了放疗,但第 5 次又迅速复发。讨论:这种类型的肉瘤在临床、组织学和进化上存在很大的多态性,导致发病率被低估,这也是诊断延误的原因。复发很频繁,通常是局部复发。最初的广泛手术切除是参考治疗方法,直接影响 DFSP 的预后。根据多项研究,复发可能取决于手术切除的质量,但也可能归因于遗传或环境因素,或肉瘤组织学亚型的变化。结论Darier Ferrand 是一种不常见的局部恶性肿瘤,其演变风险主要取决于初次切除的质量。初诊手术做得好的患者治愈的几率明显高于抢救性手术。因此,肿瘤切除必须广泛而深入,并牺牲深部的健康屏障。
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引用次数: 0
Persistent Left Superior Vena Cava: A Case Report and Review of the Literature 持续存在的左上腔静脉:病例报告与文献综述
Pub Date : 2024-05-09 DOI: 10.36347/sjmcr.2024.v12i05.007
M. Mahir, J. A. S. Abdesadeque, B. Slioui, S. Belasri, N. Hammoune, A. Mouhsine
The persistence of the left superior vena cava (LSVC) is a rare and benign congenital malformation. It is often asymptomatic, and its discovery is usually incidental in the majority of cases. This venous malformation was identified incidentally in a 60-year-old woman during thoracic multi-detector computed tomography (MDCT), which was performed with the suspicion of intra-thoracic malignancy. This is associated with abnormal venous return and an atrial septal communication.
左上腔静脉(LSVC)持续存在是一种罕见的良性先天性畸形。它通常没有症状,而且大多数病例都是偶然发现的。一名 60 岁的女性在胸腔多载体计算机断层扫描(MDCT)中意外发现了这种静脉畸形,当时她怀疑自己患有胸腔内恶性肿瘤。这与异常静脉回流和房间隔沟通有关。
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引用次数: 0
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Scholars Journal of Medical Case Reports
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