Pub Date : 1984-07-01DOI: 10.1080/00362178485380531
Y. Ishibashi, Y. Matsumoto
Oral ketoconazole (100 mg daily for 3 weeks) markedly reduced the severity of experimental Candida albicans keratitis in a group of 10 rabbits. Clinical scores of affected eyes were statistically significantly lower in the treated group than in a control group of 10 untreated rabbits. All cultures of corneal scrapings in the treated eyes were negative on the 15th day after the inoculation, whilst three positive cultures were still obtained on the 21st day in the control animals. Histopathological examination of eyes from treated and untreated rabbits showed great differences in the intensity of inflammatory changes in the two groups.
{"title":"Oral ketoconazole therapy for experimental candida albicans keratitis in rabbits.","authors":"Y. Ishibashi, Y. Matsumoto","doi":"10.1080/00362178485380531","DOIUrl":"https://doi.org/10.1080/00362178485380531","url":null,"abstract":"Oral ketoconazole (100 mg daily for 3 weeks) markedly reduced the severity of experimental Candida albicans keratitis in a group of 10 rabbits. Clinical scores of affected eyes were statistically significantly lower in the treated group than in a control group of 10 untreated rabbits. All cultures of corneal scrapings in the treated eyes were negative on the 15th day after the inoculation, whilst three positive cultures were still obtained on the 21st day in the control animals. Histopathological examination of eyes from treated and untreated rabbits showed great differences in the intensity of inflammatory changes in the two groups.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"245 1","pages":"323-30"},"PeriodicalIF":0.0,"publicationDate":"1984-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85163265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-07-01DOI: 10.1080/00362178485380521
O. Shimokawa, H. Nakayama
A rough-colony mutant of Candida albicans was isolated after ultraviolet mutagenesis. The mutant contained approximately half the normal amount of the cell wall mannan, the acetolysis pattern of which was indistinguishable from that of the wild-type counterpart. However, the extent of phosphorylation in the mutant mannan was about 12% of the value for wild type.
{"title":"Isolation of a Candida albicans mutant with reduced content of cell wall mannan and deficient mannan phosphorylation.","authors":"O. Shimokawa, H. Nakayama","doi":"10.1080/00362178485380521","DOIUrl":"https://doi.org/10.1080/00362178485380521","url":null,"abstract":"A rough-colony mutant of Candida albicans was isolated after ultraviolet mutagenesis. The mutant contained approximately half the normal amount of the cell wall mannan, the acetolysis pattern of which was indistinguishable from that of the wild-type counterpart. However, the extent of phosphorylation in the mutant mannan was about 12% of the value for wild type.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"63 1","pages":"315-21"},"PeriodicalIF":0.0,"publicationDate":"1984-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83061982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-07-01DOI: 10.1080/00362178485380471
A. Kamalam, A. Thambiah
Invasion of muscle tissue in addition to dermis and subcutaneous tissue by Basidiobolus haptosporus is reported in a 40-year-old female housewife. This infection followed intramuscular injection injury of the right gluteal region. Oral KI cured the condition completely in 6 months. Intramuscular implantation of B. haptosporus by the injection needle is the probable mode of infection in this case. Possible blood vessel invasion seen in histology suggests the possibility of dissemination of the fungus.
{"title":"Muscle invasion by Basidiobolus haptosporus.","authors":"A. Kamalam, A. Thambiah","doi":"10.1080/00362178485380471","DOIUrl":"https://doi.org/10.1080/00362178485380471","url":null,"abstract":"Invasion of muscle tissue in addition to dermis and subcutaneous tissue by Basidiobolus haptosporus is reported in a 40-year-old female housewife. This infection followed intramuscular injection injury of the right gluteal region. Oral KI cured the condition completely in 6 months. Intramuscular implantation of B. haptosporus by the injection needle is the probable mode of infection in this case. Possible blood vessel invasion seen in histology suggests the possibility of dissemination of the fungus.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"57 1","pages":"273-7"},"PeriodicalIF":0.0,"publicationDate":"1984-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82325891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-07-01DOI: 10.1080/00362178485380561
M. Rubio, C. Vroey, E. Chalon, D. Swinne
Isolation of Cryptococcus neoformans is enhanced when methyl violet at 2 mg l-1 is added to the usual Guizotia abyssinica medium. In preliminary tests the medium has also proved useful for isolating C. neoformans from other sources.
{"title":"An improved medium for the isolation of Cryptococcus neoformans from pigeon droppings.","authors":"M. Rubio, C. Vroey, E. Chalon, D. Swinne","doi":"10.1080/00362178485380561","DOIUrl":"https://doi.org/10.1080/00362178485380561","url":null,"abstract":"Isolation of Cryptococcus neoformans is enhanced when methyl violet at 2 mg l-1 is added to the usual Guizotia abyssinica medium. In preliminary tests the medium has also proved useful for isolating C. neoformans from other sources.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"457 1","pages":"345-6"},"PeriodicalIF":0.0,"publicationDate":"1984-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78292547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-07-01DOI: 10.1080/00362178485380551
K. Kobayashi, H. Suginaka
Cell surface proteins from eight Candida species were compared by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The cell wall proteins of these species were similar in their electrophoretic patterns. On the other hand, differences were detected among the patterns of membrane proteins, although C. albicans serotypes A and B gave similar electrophoretic patterns, and so did two species (C. pseudotropicalis and C. parapsilosis).
{"title":"Comparison of cell wall and membrane proteins from eight Candida species.","authors":"K. Kobayashi, H. Suginaka","doi":"10.1080/00362178485380551","DOIUrl":"https://doi.org/10.1080/00362178485380551","url":null,"abstract":"Cell surface proteins from eight Candida species were compared by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The cell wall proteins of these species were similar in their electrophoretic patterns. On the other hand, differences were detected among the patterns of membrane proteins, although C. albicans serotypes A and B gave similar electrophoretic patterns, and so did two species (C. pseudotropicalis and C. parapsilosis).","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"362 1","pages":"341-4"},"PeriodicalIF":0.0,"publicationDate":"1984-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74155757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-07-01DOI: 10.1080/00362178485380461
P. Gough, D. Warnock, M. Richardson, N. J. Mansell, J. M. King
Levels of anti-Candida albicans immunoglobulin A (IgA) and IgG were measured by enzyme-linked immunosorbent assay in serum and cervicovaginal secretions from 64 non-pregnant women with vaginal candidosis and 158 uninfected non-pregnant women. Specific IgA and IgG were detected in the serum and secretions of all 222 women. There was no significant difference between the mean levels of specific IgA or IgG in secretions from women with candidosis and those of uninfected women. Neither was there a significant difference between mean levels of specific IgA or IgG when women using oral contraception were compared with others who were not. There was a significant correlation between the levels of IgA and IgG in serum and secretions from women with candidosis and from uninfected women. Blastospore and hyphal forms of C. albicans were seen in vaginal smears from 29 of the 64 women with culture-proven candidosis: in nine, both IgA- and IgG-coated C. albicans cells were recovered from the genital tract; in a tenth, IgG-coated cells were found.
{"title":"IgA and IgG antibodies to Candida albicans in the genital tract secretions of women with or without vaginal candidosis.","authors":"P. Gough, D. Warnock, M. Richardson, N. J. Mansell, J. M. King","doi":"10.1080/00362178485380461","DOIUrl":"https://doi.org/10.1080/00362178485380461","url":null,"abstract":"Levels of anti-Candida albicans immunoglobulin A (IgA) and IgG were measured by enzyme-linked immunosorbent assay in serum and cervicovaginal secretions from 64 non-pregnant women with vaginal candidosis and 158 uninfected non-pregnant women. Specific IgA and IgG were detected in the serum and secretions of all 222 women. There was no significant difference between the mean levels of specific IgA or IgG in secretions from women with candidosis and those of uninfected women. Neither was there a significant difference between mean levels of specific IgA or IgG when women using oral contraception were compared with others who were not. There was a significant correlation between the levels of IgA and IgG in serum and secretions from women with candidosis and from uninfected women. Blastospore and hyphal forms of C. albicans were seen in vaginal smears from 29 of the 64 women with culture-proven candidosis: in nine, both IgA- and IgG-coated C. albicans cells were recovered from the genital tract; in a tenth, IgG-coated cells were found.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"147 2","pages":"265-71"},"PeriodicalIF":0.0,"publicationDate":"1984-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91466197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-07-01DOI: 10.1080/00362178485380501
S. Honbo, P. Standard, A. Padhye, L. Ajello, L. Kaufman
We analyzed the exoantigens of 54 isolates belonging to the pathogenic Cladosporium species. Cladophialophora ajelloi was found to be antigenically identical to Cladosporium carrionii. All human and cat isolates of C. bantianum and C. trichoides were found to share the same antigens. Although cross-reactions were observed among the four species of Cladosporium: C. carrionii, C. bantianum, c. herbarum, and C. cladosporioides they were identified and differentiated specifically with four monospecific factor sera obtained through absorption procedures. The exoantigen serologic procedure also permitted us to identify cultures of these four Cladosporium spp. within 8 days.
{"title":"Antigenic relationships among Cladosporium species of medical importance.","authors":"S. Honbo, P. Standard, A. Padhye, L. Ajello, L. Kaufman","doi":"10.1080/00362178485380501","DOIUrl":"https://doi.org/10.1080/00362178485380501","url":null,"abstract":"We analyzed the exoantigens of 54 isolates belonging to the pathogenic Cladosporium species. Cladophialophora ajelloi was found to be antigenically identical to Cladosporium carrionii. All human and cat isolates of C. bantianum and C. trichoides were found to share the same antigens. Although cross-reactions were observed among the four species of Cladosporium: C. carrionii, C. bantianum, c. herbarum, and C. cladosporioides they were identified and differentiated specifically with four monospecific factor sera obtained through absorption procedures. The exoantigen serologic procedure also permitted us to identify cultures of these four Cladosporium spp. within 8 days.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"49 1","pages":"301-10"},"PeriodicalIF":0.0,"publicationDate":"1984-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74210039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-05-01DOI: 10.1080/00362178485380331
L. Samaranayake, J. Raeside, T. Macfarlane
The phospholipase activity of 41 isolates of oral Candida species was determined by a plate assay. Seventy nine per cent of the C. albicans isolates were phospholipase producers whereas none of the C. tropicalis, C. glabrata or C. parapsilosis isolates produced the enzyme. The degree of phospholipase activity (Pz value) of individual isolates was remarkably constant despite the large variation in activity among different isolates. Experiments with 10 phospholipase positive C. albicans isolates indicate that phospholipase production in vitro is limited to a narrow pH range (c. 3.6-4.7) and is suppressed by increasing concentrations of sucrose and galactose in the media (r = 0.9). Hence, candidal phospholipases seem to play a complex role in the aetiopathology of human candidoses.
{"title":"Factors affecting the phospholipase activity of Candida species in vitro.","authors":"L. Samaranayake, J. Raeside, T. Macfarlane","doi":"10.1080/00362178485380331","DOIUrl":"https://doi.org/10.1080/00362178485380331","url":null,"abstract":"The phospholipase activity of 41 isolates of oral Candida species was determined by a plate assay. Seventy nine per cent of the C. albicans isolates were phospholipase producers whereas none of the C. tropicalis, C. glabrata or C. parapsilosis isolates produced the enzyme. The degree of phospholipase activity (Pz value) of individual isolates was remarkably constant despite the large variation in activity among different isolates. Experiments with 10 phospholipase positive C. albicans isolates indicate that phospholipase production in vitro is limited to a narrow pH range (c. 3.6-4.7) and is suppressed by increasing concentrations of sucrose and galactose in the media (r = 0.9). Hence, candidal phospholipases seem to play a complex role in the aetiopathology of human candidoses.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"8 3 1","pages":"201-7"},"PeriodicalIF":0.0,"publicationDate":"1984-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78269732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-05-01DOI: 10.1080/00362178485380341
S. Honbo, A. Padhye, L. Ajello
Twelve of 21 isolates of Cladosporium carrionii, when grown on nutritionally deficient media such as lactrimel agar, hay infusion agar, diluted corn meal dextrose agar, and water agar, produced urniform phialides and phialoconidia identical with those produced by two isolates of Cladophialophora ajelloi. All isolates of C. carrionii and Cph. ajelloi hydrolyzed urea in 7 days, but failed to liquefy gelatin. The decomposition of casein, xanthine, hypoxanthine, and tyrosine was found to be of no diagnostic value because of the variable results given by the isolates of C. carrionii. None of the C. bantianum isolates or commonly encountered saprophytic species of Cladosporium, such as C. cladosporioides and C. herbarum, showed the ability to form phialides on any of the media tested. Because of the identical nature of the two synanamorphs of Cph. ajelloi, namely the Cladosporium-type and the Phialophora-type, with those of C. carionii, Cph. ajelloi is considered to be a later synonym of C. carrionii. The Latin description of C. carrionii is emended to include the Phialophora anamorph.
{"title":"The relationship of Cladosporium carrionii to Cladophialophora ajelloi.","authors":"S. Honbo, A. Padhye, L. Ajello","doi":"10.1080/00362178485380341","DOIUrl":"https://doi.org/10.1080/00362178485380341","url":null,"abstract":"Twelve of 21 isolates of Cladosporium carrionii, when grown on nutritionally deficient media such as lactrimel agar, hay infusion agar, diluted corn meal dextrose agar, and water agar, produced urniform phialides and phialoconidia identical with those produced by two isolates of Cladophialophora ajelloi. All isolates of C. carrionii and Cph. ajelloi hydrolyzed urea in 7 days, but failed to liquefy gelatin. The decomposition of casein, xanthine, hypoxanthine, and tyrosine was found to be of no diagnostic value because of the variable results given by the isolates of C. carrionii. None of the C. bantianum isolates or commonly encountered saprophytic species of Cladosporium, such as C. cladosporioides and C. herbarum, showed the ability to form phialides on any of the media tested. Because of the identical nature of the two synanamorphs of Cph. ajelloi, namely the Cladosporium-type and the Phialophora-type, with those of C. carionii, Cph. ajelloi is considered to be a later synonym of C. carrionii. The Latin description of C. carrionii is emended to include the Phialophora anamorph.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"9 1","pages":"209-18"},"PeriodicalIF":0.0,"publicationDate":"1984-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72934067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1984-05-01DOI: 10.1080/00362178485380351
I. Takiuchi, Y. Sei, H. Takagi, M. Negi
The extracellular keratinase of Microsporum canis released peptides from alpha-type fibrous protein and the membranous fraction isolated from human stratum corneum. Inhibition of the enzyme by phenylmethyl-sulfonylfluoride and its weak inhibition by N-ethylmaleimide and etheneglycol tetra-acetic acid indicated that it is probably a serine proteinase.
{"title":"Partial characterization of the extracellular keratinase from Microsporum canis.","authors":"I. Takiuchi, Y. Sei, H. Takagi, M. Negi","doi":"10.1080/00362178485380351","DOIUrl":"https://doi.org/10.1080/00362178485380351","url":null,"abstract":"The extracellular keratinase of Microsporum canis released peptides from alpha-type fibrous protein and the membranous fraction isolated from human stratum corneum. Inhibition of the enzyme by phenylmethyl-sulfonylfluoride and its weak inhibition by N-ethylmaleimide and etheneglycol tetra-acetic acid indicated that it is probably a serine proteinase.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"9 1","pages":"219-24"},"PeriodicalIF":0.0,"publicationDate":"1984-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90726123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：