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Continuous spinal anesthesia in a case of Eisenmenger syndrome undergoing TURBT- A case report. 持续脊髓麻醉在艾森曼格综合征行TURBT 1例报告。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_65_25
Hassan M Ahmed

Eisenmenger syndrome (ES) represents the extreme phenotype of pulmonary hypertension. We present the anesthetic management of an ES case undergoing transurethral resection of bladder tumor (TURBT). A 56-year-old lady who is known to suffer from ES diagnosed with a urinary bladder multifocal tumor was scheduled for TURBT. We describe here the successful management of the ES case undergoing TURBT using continuous spinal anesthesia.

艾森曼格综合征(ES)代表肺动脉高压的极端表型。我们报告一例经尿道膀胱肿瘤切除术(turt)的ES病例的麻醉处理。一位已知患有ES的56岁女性,诊断为膀胱多灶性肿瘤,计划进行TURBT。我们在此描述了连续脊髓麻醉下进行turt的ES病例的成功治疗。
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引用次数: 0
Large left internal jugular vein determined during cardiac surgery: A case report. 心脏手术中发现左颈内静脉大:1例报告。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_38_25
Kadİrİye S Elden, Helİn Ozler, Hasan Hepaguslar

This case report presents the significant enlargement of the left internal jugular vein (IJV) detected during ultrasound (US)-guided central venous catheterization (CVC) in an adult patient undergoing cardiac surgery. An 81-year-old female patient who had severe mitral valve regurgitation, severe tricuspid valve regurgitation, and pulmonary hypertension was scheduled for Mitral Valve Replacement and DeVega Tricuspidoplasty. The patient had many comorbidities, so she was on antihypertensive (nebivolol), antithrombotic (rivaroxaban), and antidiabetic (insulin) medications. After anesthesia induction, the patient was positioned for CVC. Ultasound guidance showed that the anteroposterior diameter of the right IJV was small and the degree of overlapping of carotid artery (CA) was high. Left side was evaluated before starting the procedure. Marked enlargement of the left IJV and less overlapping of CA was observed. Left IJV catheterization was decided and performed without any complication. The surgery lasted for 3 hours and was completed uneventfully. Although right IJV is usually preferred for CVC where central intravenous access is required, it is advisable to evaluate the left IJV when the right one has a small diameter and there is a significant overlapping of right CA. In these cases, the choice for CVC side should be based on the data which is obtained from both sides.

本病例报告了一例接受心脏手术的成人患者,在超声(US)引导下的中心静脉置管(CVC)中发现左侧颈内静脉(IJV)明显扩大。一位81岁的女性患者因严重的二尖瓣返流、严重的三尖瓣返流和肺动脉高压被安排进行二尖瓣置换术和DeVega三尖瓣成形术。患者有许多合并症,因此她服用降压药(奈比洛尔)、抗血栓药(利伐沙班)和抗糖尿病(胰岛素)药物。麻醉诱导后,对患者进行CVC定位。超声提示右侧IJV前后径小,颈动脉(CA)重叠程度高。手术前对左侧进行了评估。左侧IJV明显增大,CA重叠较少。决定并实施左侧IJV置管,无任何并发症。手术持续了3个小时,顺利完成。虽然在需要中心静脉通路的CVC中,通常首选右侧IJV,但当右侧IJV直径较小且与右侧CA有明显重叠时,建议评估左侧IJV。在这种情况下,CVC侧的选择应根据双方获得的数据。
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引用次数: 0
The novel etomidate analog: A potential induction agent. 新型依托咪酯类似物:一种潜在的诱导剂。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_503_25
Konica Chittoria, Ankur Sharma

Etomidate is the agent of choice for the induction of anesthesia in patients with cardiovascular illness, hypotension, or shock. Notwithstanding its numerous attributes, etomidate's most notable adverse impact is adrenocortical suppression. Due to these concerns, the creation of an etomidate alternative that maintains its beneficial effects while mitigating adverse outcomes became essential. This article will focus on the new etomidate analog, methoxyethyl etomidate hydrochloride, referred to as ET-26.

依托咪酯是心血管疾病、低血压或休克患者诱导麻醉的首选药物。尽管有许多特性,依托咪酯最显著的不良影响是肾上腺皮质抑制。由于这些担忧,创造一种替代依托咪酯,保持其有益作用,同时减轻不良后果变得至关重要。本文将重点介绍新的依托咪酯类似物,盐酸甲氧乙基依托咪酯,简称ET-26。
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引用次数: 0
Optimal lidocaine propofol mixture for painless induction of anesthesia. 利多卡因、异丙酚混合物无痛诱导麻醉的最佳选择。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_55_25
Hitham M A Elsayed, Roshdi R Al-Metwalli, Mohammed Abdelraheem, Fawzy Badawy

Objective: To determine the median effective dose (ED50) of 2% lidocaine mixed with propofol for preventing pain during the induction of anesthesia using a modified Dixon's up-and-down method.

Materials and methods: Thirty ASA (American Society of Anesthesiologists) grade I and II patients, aged 18-60 years, undergoing elective surgery were enrolled. Using the modified Dixon's up-and-down method, patients received varying doses of lidocaine mixed with 20 mL of propofol MCT/LCT (Medium Chain Triglyceride/Long Chain Triglyceride) emulsion. The primary outcome was the calculation of the ED50 of 2% lidocaine, defined as the midpoint dose at which 50% of patients experienced painless injection. Secondary outcomes included pain scores during injection, heart rate changes, and withdrawal movements.

Results: Thirty patients completed the study. The ED50 of lidocaine premixed with 20 mL of propofol MCT/LCT emulsion to prevent pain during the induction of anesthesia was 32.14 mg (95% CI = 32.09 mg-32.18 mg), equivalent to 1.46 mg/mL (95% CI: 1.02 mg/mL-1.91 mg/mL). Demographic and clinical characteristics of patients who experienced pain and those who did not were not statistically significant.

Conclusion: Our study concluded that the ED50 of lidocaine premixed with 20 mL of propofol to prevent pain during the induction of anesthesia was 32.14 mg (95% CI = 32.09 mg-32.18 mg), equivalent to 1.46 mg/mL (95% CI: 1.02-1.91 mg/mL).

目的:采用改进的Dixon上下法确定2%利多卡因与异丙酚混合用于麻醉诱导疼痛的中位有效剂量(ED50)。材料和方法:入选ASA (American Society of Anesthesiologists) I级和II级患者30例,年龄18-60岁,行择期手术。采用改良的Dixon上下法,患者接受不同剂量的利多卡因与20ml异丙酚MCT/LCT(中链甘油三酯/长链甘油三酯)乳剂混合。主要结果是计算2%利多卡因的ED50,定义为50%的患者经历无痛注射的中点剂量。次要结局包括注射时疼痛评分、心率变化和停药动作。结果:30例患者完成了研究。利多卡因预混20ml异丙酚MCT/LCT乳剂预防麻醉诱导时疼痛的ED50为32.14 mg (95% CI = 32.09 mg-32.18 mg),相当于1.46 mg/mL (95% CI: 1.02 mg/mL-1.91 mg/mL)。经历过疼痛和没有经历过疼痛的患者的人口学和临床特征没有统计学意义。结论:本研究认为,利多卡因与20ml异丙酚预混用于麻醉诱导时预防疼痛的ED50为32.14 mg (95% CI = 32.09 mg-32.18 mg),相当于1.46 mg/mL (95% CI: 1.02-1.91 mg/mL)。
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引用次数: 0
Preoperative information as predictor of the patient's fear and anxiety before surgery Systematic review of qualitative and quantitative literature. 术前信息作为患者术前恐惧和焦虑的预测因子对定性和定量文献的系统回顾。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_120_25
Ferid Krupic, Melissa Krupic, Emina Dervisevic, Mirza Kovacevic, Tarik Bujakovic

Background: Between 10% and 80% of surgical patients experience some form of fear and anxiety before surgery. This is often attributed to inadequate or incorrect preoperative information.

Objectives: This study aimed to critically evaluate and compile research that describes the impact of preoperative information on the patient's well-being before surgery.

Methods: A systematic search was conducted on PubMed, Medline, CHINAL, Embase, and the Cochrane Library database for qualitative and quantitative literature regarding factors influencing patients' well-being before surgery. An inductive thematic analysis generated categories and subcategories. Nineteen studies were included.

Results: Two main categories emerged from the thematic analysis of the included articles. These were the direct impact of information on fear and anxiety and the indirect impact of information on fear and anxiety. Information from healthcare professionals, alternative sources of information, shortage of healthcare professionals, music, and inability to receive information were some of the factors that can influence the well-being of patients before surgery. There are different reasons for the patient's fear and anxiety preoperatively, as well as the importance of direct and indirect information and other methods. For some patients, however, too much information could cause more fear and anxiety.

Conclusion: The importance of the patient's discomfort being highlighted by the healthcare professionals emerges clearly and shows negative experiences in those cases where the patient feels his fears and concerns are not being addressed. More qualitative and quantitative research in the same theme, education and using person-centred care, and the right amount of information based on the patient's wishes are needed to improve the patient's well-being.

背景:10%到80%的手术患者在手术前都会经历某种形式的恐惧和焦虑。这通常归因于术前信息不充分或不正确。目的:本研究旨在批判性地评估和汇编描述术前信息对术前患者健康影响的研究。方法:系统检索PubMed、Medline、CHINAL、Embase和Cochrane Library数据库,获取影响患者术前幸福感因素的定性和定量文献。归纳的专题分析产生了类别和子类别。纳入了19项研究。结果:从纳入的文章的专题分析中出现了两个主要类别。这些是信息对恐惧和焦虑的直接影响以及信息对恐惧和焦虑的间接影响。来自医疗保健专业人员的信息、其他信息来源、医疗保健专业人员的短缺、音乐和无法接收信息是影响患者术前健康的一些因素。患者术前恐惧和焦虑的原因不同,以及直接和间接信息等方法的重要性。然而,对于一些患者来说,过多的信息可能会导致更多的恐惧和焦虑。结论:医疗保健专业人员强调患者不适的重要性,在患者感到恐惧和担忧没有得到解决的情况下,这种情况清楚地显示出负面体验。为了改善病人的健康,需要在同一主题、教育和使用以人为本的护理方面进行更多的定性和定量研究,并根据病人的意愿提供适量的信息。
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引用次数: 0
Anesthetic management of a patient with tracheocele posted for a routine surgery. 气管膨出患者常规手术的麻醉处理。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_167_25
Aakash Agarwal, Krishan Yogesh Sawhney, Sabih Ahmad

The incidence of tracheocele is rare, but whenever encountered, Tracheoceles must be meticulously managed owing to the grave complications associated with them. Here, we report the successful management of a case of orbital tumor who underwent orbital exenteration and was incidentally preoperatively diagnosed with having a large tracheocele in the lower neck region.

气管膨出的发生率是罕见的,但无论何时遇到,气管膨出必须精心处理,由于严重的并发症与他们有关。在此,我们报告一例成功的眼眶肿瘤的管理,谁接受了眼眶摘除,并偶然的术前诊断为有一个大的气管囊肿在下颈部区域。
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引用次数: 0
Infantile postoperative residual curarization (IPORC) - A prospective observational study. 婴儿术后残留curarization (IPORC) -一项前瞻性观察研究。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_394_25
Christoph Unterbuchner, Julian Kögel, Katharina Ehehalt, Thomas Metterlein

Objective: Residual neuromuscular blockade (RNMB), defined as a train-of-four ratio (TOFR) <0.90, is a complication of neuromuscular blocking agents (NMBA). Data about RNMB in children are rare. This single-center observational trial evaluated the rate of neuromuscular monitoring (NMM), the incidence, and consequences of RNMB in pediatrics.

Methods: Children over 1 month undergoing elective and urgent surgery during core work hours receiving NMBA were included in an 84-day observation period. When the anesthesiologist decided to extubate, a blinded investigator measured the TOFR by acceleromyography. Data on demographics, surgery, anesthesia, and outcome were recorded. Comparison of qualitative variables was done using the chi-square test. The Mann-Whitney U test was used to compare quantitative variables between patients with or without TOFR <0.90. P <0.05 was considered significant.

Results: Eighty-nine children were included in the analysis. Rate of quantitative and qualitative NMM was 65.2% and 5.6%, respectively. Incidence of RNMB was 10.1% with TOFRs between 0.78 and 0.89 in 8 children and a TOFR of 0.48 in one child. Median time from the last NMBA administration to the TOFR before extubation was significantly shorter in patients with a TOFR <0.90 in comparison with a TOFR ≥0.90 (88 vs. 110 min). In the RNMB group, qualitative NMM was significantly more often used compared with the no RNMB group (22.2% vs. 3.8%). Adverse events were rare with no significant differences between the two groups.

Conclusion: RNMB in children is a relevant hazard. Qualitative NMM is not reliable to exclude RNMB. Institutional training programs on neuromuscular management in children may be helpful to improve the rate of quantitative NMM.

目的:残余神经肌肉阻滞(rmb),定义为四组比率(TOFR)方法:在核心工作时间接受选择性和紧急手术的1个月以上儿童接受NMBA,进行84天的观察。当麻醉师决定拔管时,盲法研究者通过加速肌图测量TOFR。记录人口统计学、手术、麻醉和结果的数据。质变量比较采用卡方检验。采用Mann-Whitney U检验比较TOFR P患者与非TOFR P患者的数量变量。结果:89名儿童纳入分析。定量和定性NMM检出率分别为65.2%和5.6%。8例患儿rmb发生率为10.1%,TOFR在0.78 ~ 0.89之间,1例患儿TOFR为0.48。tfr患者从最后一次NMBA给药到拔管前tfr的中位时间明显缩短。结论:小儿rmb是一种相关的危险。定性NMM不可靠,不能排除人民币。儿童神经肌肉管理的制度性培训项目可能有助于提高定量NMM的发生率。
{"title":"Infantile postoperative residual curarization (IPORC) - A prospective observational study.","authors":"Christoph Unterbuchner, Julian Kögel, Katharina Ehehalt, Thomas Metterlein","doi":"10.4103/sja.sja_394_25","DOIUrl":"10.4103/sja.sja_394_25","url":null,"abstract":"<p><strong>Objective: </strong>Residual neuromuscular blockade (RNMB), defined as a train-of-four ratio (TOFR) <0.90, is a complication of neuromuscular blocking agents (NMBA). Data about RNMB in children are rare. This single-center observational trial evaluated the rate of neuromuscular monitoring (NMM), the incidence, and consequences of RNMB in pediatrics.</p><p><strong>Methods: </strong>Children over 1 month undergoing elective and urgent surgery during core work hours receiving NMBA were included in an 84-day observation period. When the anesthesiologist decided to extubate, a blinded investigator measured the TOFR by acceleromyography. Data on demographics, surgery, anesthesia, and outcome were recorded. Comparison of qualitative variables was done using the chi-square test. The Mann-Whitney U test was used to compare quantitative variables between patients with or without TOFR <0.90. <i>P</i> <0.05 was considered significant.</p><p><strong>Results: </strong>Eighty-nine children were included in the analysis. Rate of quantitative and qualitative NMM was 65.2% and 5.6%, respectively. Incidence of RNMB was 10.1% with TOFRs between 0.78 and 0.89 in 8 children and a TOFR of 0.48 in one child. Median time from the last NMBA administration to the TOFR before extubation was significantly shorter in patients with a TOFR <0.90 in comparison with a TOFR ≥0.90 (88 vs. 110 min). In the RNMB group, qualitative NMM was significantly more often used compared with the no RNMB group (22.2% vs. 3.8%). Adverse events were rare with no significant differences between the two groups.</p><p><strong>Conclusion: </strong>RNMB in children is a relevant hazard. Qualitative NMM is not reliable to exclude RNMB. Institutional training programs on neuromuscular management in children may be helpful to improve the rate of quantitative NMM.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 4","pages":"566-572"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of fascial plane blocks and elastosonography in the assessment of stiffness in chronic myofascial pain. 筋膜平面阻滞和弹性超声在评估慢性肌筋膜疼痛的僵硬度中的作用。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_129_25
Pierfrancesco Fusco, Walter Ciaschi, Gian Marco Petroni, Chiara Maggiani, Emanuele Nazzarro

Chronic myofascial pain is a very common pathological condition, but the diagnosis can be complex. Elastosonography can be a valuable aid to diagnosis by demonstrating increased stifness of the myofascial unit. In addition, it can demonstrate the reduction in stifness after performing a fascial plane block by allowing the effectiveness of the block to be evaluated. In this case series we present cases of patients evaluated with elastosonography before and after fascial plane block and demonstrate the differences.

慢性肌筋膜疼痛是一种非常常见的病理状况,但诊断可能很复杂。弹性超声可以通过显示肌筋膜单位僵硬度的增加而对诊断提供有价值的帮助。此外,它还可以通过评估筋膜平面阻滞的有效性来证明筋膜平面阻滞后刚度的降低。在这个病例系列中,我们介绍了患者在筋膜平面阻滞之前和之后用弹性超声评估的病例,并展示了差异。
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引用次数: 0
Fragmentation of epidural catheter-need consensus on management. 硬膜外导管碎裂-需要共识处理。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_289_25
Rekha Bhatia, Saumitra Zope, Prachi Ganokar, Rupak Kundu

Lumbar epidural anesthesia is an important part of labor analgesia. Despite common complications, lumbar epidurals are considered the most effective pain management option during childbirth. Fracture of the epidural catheter during removal is an uncommon but known complication, but fragmentation of the catheter during insertion is extremely uncommon. There are several reasons for catheter fracture during removal; however, catheter fracture during insertion can occur for two main reasons in labor epidurals. The first reason is if the anesthetist pulls the catheter while the Tuohy needle is still in place, and the second is when the catheter is removed during active labor contractions. We describe the occurrence of such an event in a primiparous patient, where the epidural catheter fractured during insertion. A brief review is provided to prevent and manage such complications.

腰硬膜外麻醉是分娩镇痛的重要组成部分。尽管常见的并发症,腰硬膜外被认为是分娩时最有效的疼痛管理选择。硬膜外导管在取出过程中断裂是一种罕见但已知的并发症,但在插入过程中导管碎裂是极为罕见的。导管在拔除过程中断裂的原因有很多;然而,在硬膜外分娩时,导管在插入过程中发生断裂主要有两个原因。第一个原因是麻醉师在Tuohy针还在的情况下拔导管,第二个原因是在主动宫缩期间取出导管。我们描述发生这样的事件在初产患者,其中硬膜外导管断裂在插入。本文就预防和处理此类并发症作一简要综述。
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引用次数: 0
Lumbo-sacral erector spinae plane and femoral nerve blocks for hip fracture surgery in a critical patient. 腰骶竖肌脊柱平面和股神经阻滞在髋部骨折手术中的应用。
IF 1.4 Q3 ANESTHESIOLOGY Pub Date : 2025-10-01 Epub Date: 2025-09-03 DOI: 10.4103/sja.sja_232_25
Lorenza Sbucafratta, Francesco Marrone
{"title":"Lumbo-sacral erector spinae plane and femoral nerve blocks for hip fracture surgery in a critical patient.","authors":"Lorenza Sbucafratta, Francesco Marrone","doi":"10.4103/sja.sja_232_25","DOIUrl":"10.4103/sja.sja_232_25","url":null,"abstract":"","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 4","pages":"670-672"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Saudi Journal of Anaesthesia
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