Pub Date : 2019-01-01DOI: 10.1016/B978-0-12-800050-2.00004-8
M. Fex
{"title":"5-Hydroxytryptamine in the Endocrine Pancreas","authors":"M. Fex","doi":"10.1016/B978-0-12-800050-2.00004-8","DOIUrl":"https://doi.org/10.1016/B978-0-12-800050-2.00004-8","url":null,"abstract":"","PeriodicalId":21561,"journal":{"name":"Serotonin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86435600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-05DOI: 10.5772/INTECHOPEN.81506
S. Pérez
Serotonin is one of the most important neurotransmitters involved in emotional regulation, which affect decision-making. In fact, specific genes regulate the transporter protein of serotonin, making people prone to show or not higher amygdala activation. Higher activation of specific components of the limbic system, such as amygdala, results in a higher susceptibility to make decision taking into account the environmental and emotional aspects and not only rational elaborations of the facts. It makes the response of decision-making more visceral or emotional in contrast to people with lower amygdala activation. Therefore, the importance of serotonin regulations impacts on daily and important decisions.
{"title":"Serotonin and Emotional Decision-Making","authors":"S. Pérez","doi":"10.5772/INTECHOPEN.81506","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.81506","url":null,"abstract":"Serotonin is one of the most important neurotransmitters involved in emotional regulation, which affect decision-making. In fact, specific genes regulate the transporter protein of serotonin, making people prone to show or not higher amygdala activation. Higher activation of specific components of the limbic system, such as amygdala, results in a higher susceptibility to make decision taking into account the environmental and emotional aspects and not only rational elaborations of the facts. It makes the response of decision-making more visceral or emotional in contrast to people with lower amygdala activation. Therefore, the importance of serotonin regulations impacts on daily and important decisions.","PeriodicalId":21561,"journal":{"name":"Serotonin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74325305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-05DOI: 10.5772/INTECHOPEN.80711
Adela Hilda Onuțu, D. Dîrzu, C. Petrişor
Serotonin has a particular place in the modulation of pain. Experimental studies have described 5-HT1–7 receptors and their effects on facilitation or inhibition of nociceptive input. Selective serotonin reuptake inhibitors (SSRIs) and serotoninnorepinephrine reuptake inhibitors showed efficient and safer than tricyclic antidepressants in neuropathic pain. Although there is evidence regarding the beneficial impact of SSRIs in the multimodal acute pain management, studies are still searching for the potentially favorable effect of these drugs in the prevention of chronic postoperative pain. The scope of this chapter would be to update the knowledge regarding serotonin involving in pain pathways and to highlight the importance and contribution of serotonin reuptake inhibitors in the multimodal pain management schemes.
{"title":"Serotonin Reuptake Inhibitors and Their Role in Chronic Pain Management","authors":"Adela Hilda Onuțu, D. Dîrzu, C. Petrişor","doi":"10.5772/INTECHOPEN.80711","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.80711","url":null,"abstract":"Serotonin has a particular place in the modulation of pain. Experimental studies have described 5-HT1–7 receptors and their effects on facilitation or inhibition of nociceptive input. Selective serotonin reuptake inhibitors (SSRIs) and serotoninnorepinephrine reuptake inhibitors showed efficient and safer than tricyclic antidepressants in neuropathic pain. Although there is evidence regarding the beneficial impact of SSRIs in the multimodal acute pain management, studies are still searching for the potentially favorable effect of these drugs in the prevention of chronic postoperative pain. The scope of this chapter would be to update the knowledge regarding serotonin involving in pain pathways and to highlight the importance and contribution of serotonin reuptake inhibitors in the multimodal pain management schemes.","PeriodicalId":21561,"journal":{"name":"Serotonin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83239440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-05DOI: 10.5772/INTECHOPEN.77956
Katiuska Satué Ambrojo, J. Poggi, María Marcilla Corzano
Serotonin (5-HT) is a neurotransmitter that has important functions such as the physiological regulation of hemostasis, blood clotting, bone metabolism, cardiovascular growth, contractile activity and gastrointestinal motility, renal function, and stress and sexual behavior, among others. In this review, we consider the potential of 5-HT to contribute to the development of various pathological conditions, including metabolic, vascular, and nervous disorders in horses. The values of 5-HT in circulation are modified under common pathological conditions. Thus, laminitis, endotoxemia, surgical cramps, recurrent airway obstruction, Cushing’s syndrome, central fatigue, and certain behavioral alterations such as stereotypes and other acute or chronic conditions can cause increased levels of 5-HT.
{"title":"Clinical Aspects Related to Plasma Serotonin in the Horse","authors":"Katiuska Satué Ambrojo, J. Poggi, María Marcilla Corzano","doi":"10.5772/INTECHOPEN.77956","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.77956","url":null,"abstract":"Serotonin (5-HT) is a neurotransmitter that has important functions such as the physiological regulation of hemostasis, blood clotting, bone metabolism, cardiovascular growth, contractile activity and gastrointestinal motility, renal function, and stress and sexual behavior, among others. In this review, we consider the potential of 5-HT to contribute to the development of various pathological conditions, including metabolic, vascular, and nervous disorders in horses. The values of 5-HT in circulation are modified under common pathological conditions. Thus, laminitis, endotoxemia, surgical cramps, recurrent airway obstruction, Cushing’s syndrome, central fatigue, and certain behavioral alterations such as stereotypes and other acute or chronic conditions can cause increased levels of 5-HT.","PeriodicalId":21561,"journal":{"name":"Serotonin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76161749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1993-01-01DOI: 10.1007/978-94-011-1920-7
P. Vanhoutte
{"title":"Serotonin: From Cell Biology to Pharmacology and Therapeutics","authors":"P. Vanhoutte","doi":"10.1007/978-94-011-1920-7","DOIUrl":"https://doi.org/10.1007/978-94-011-1920-7","url":null,"abstract":"","PeriodicalId":21561,"journal":{"name":"Serotonin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81073901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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