Sleep Science and Practice最新文献

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Transcranial magnetic stimulation therapeutic applications on sleep and insomnia: a review 经颅磁刺激在睡眠和失眠治疗中的应用综述

Sleep Science and Practice

Pub Date : 2021-02-03 DOI: 10.1186/s41606-020-00057-9

Ricardo Oroz, S. Kung, P. Croarkin, Joseph Cheung

引用次数: 11

Changes in insomnia as a risk factor for the incidence and persistence of anxiety and depression: a longitudinal community study 失眠作为焦虑和抑郁发生和持续的危险因素的变化:一项纵向社区研究

Sleep Science and Practice

Pub Date : 2021-01-12 DOI: 10.1186/s41606-020-00053-z

Magnus Johansson, M. Jansson-Fröjmark, A. Norell-Clarke, S. Linton

引用次数: 12

Association between cardiometabolic health and objectively-measured, free-living sleep parameters: a pilot study in a rural African setting 心脏代谢健康与客观测量的自由生活睡眠参数之间的关系:一项在非洲农村环境中的试点研究

Sleep Science and Practice

Pub Date : 2021-01-07 DOI: 10.1186/s41606-020-00054-y

I. Cook, Matlawa Mohlabe, H. M. Makgopa

引用次数: 3

Cardiac function and cognitive function in patients with obstructive sleep apnea 阻塞性睡眠呼吸暂停患者的心功能和认知功能

Sleep Science and Practice

Pub Date : 2021-01-04 DOI: 10.1186/s41606-020-00055-x

E. Vahedi, A. Khosravi, Rahman Alizadian, T. Badri

引用次数: 7

Palmitoylethanolamide for sleep disturbance. A double-blind, randomised, placebo-controlled interventional study. 棕榈酰乙醇酰胺治疗睡眠障碍。一项双盲、随机、安慰剂对照的干预性研究。

Sleep Science and Practice

Pub Date : 2021-01-01 Epub Date: 2021-09-10 DOI: 10.1186/s41606-021-00065-3

Amanda Rao, Phillippa Ebelt, Alistair Mallard, David Briskey

Background: Sleep is essential for wellbeing, yet sleep disturbance is a common problem linked to a wide range of health conditions. Palmitoylethanolamide (PEA) is an endogenous fatty acid amide proposed to promote better sleep via potential interaction with the endocannabinoid system.

Methods: This double-blind, randomised study on 103 adults compared the efficacy and tolerability of 8 weeks of daily supplemented PEA formulation (350 mg Levagen + ®) to a placebo. Sleep quality and quantity were measured using wrist actigraphy, a sleep diary and questionnaires.

Results: At week 8, PEA supplementation reduced sleep onset latency, time to feel completely awake and improved cognition on waking. After 8 weeks, both groups improved their sleep quality and quantity scores similarly. There was no difference between groups at baseline or week 8 for sleep quantity or quality as measured from actigraphy or sleep diaries.

Conclusion: These findings support PEA as a potential sleeping aid capable of reducing sleep onset time and improving cognition on waking.

Trial registration: Australian New Zealand Clinical Trials Registry ACTRN12618001339246. Registered 9^th August 2018.

背景:睡眠对健康至关重要，但睡眠障碍是一个与各种健康状况有关的常见问题。棕榈酰乙醇酰胺(PEA)是一种内源性脂肪酸酰胺，被认为通过与内源性大麻素系统的潜在相互作用来促进更好的睡眠。方法:这项对103名成人进行的双盲随机研究比较了每日补充PEA制剂(350 mg Levagen +®)8周与安慰剂的疗效和耐受性。通过腕部活动记录仪、睡眠日记和问卷调查来测量睡眠质量和时间。结果:在第8周，补充PEA减少了睡眠发作潜伏期，感觉完全清醒的时间，并改善了醒来时的认知。8周后，两组人的睡眠质量和睡眠时间得分都得到了相似的改善。在基线或第8周，两组之间的睡眠时间或质量通过活动记录仪或睡眠日记测量没有差异。结论:这些发现支持PEA作为一种潜在的助眠剂，能够缩短睡眠开始时间并改善清醒时的认知。试验注册:澳大利亚新西兰临床试验注册中心ACTRN12618001339246。2018年8月9日注册

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引用次数: 5

Revisiting level II sleep studies in the era of COVID-19: a theoretical economic decision model in patients with suspected obstructive sleep apnea. 重新审视新冠肺炎时代的二级睡眠研究:疑似阻塞性睡眠呼吸暂停患者的理论经济决策模型

Sleep Science and Practice

Pub Date : 2021-01-01 Epub Date: 2021-07-15 DOI: 10.1186/s41606-021-00063-5

Najib T Ayas, Rachel Jen, Brett Baumann

Background: The recent pandemic has made it more challenging to assess patients with suspected obstructive sleep apnea (OSA) with in laboratory polysomnography (PSG) due to concerns of patient and staff safety. The purpose of this study was to assess how Level II sleep studies (LII, full PSG in the home) might be utilized in diagnostic algorithms of suspected OSA using a theoretical decision model.

Methods: We examined four diagnostic algorithms for suspected OSA: an initial PSG approach, an initial LII approach, an initial Level III approach (LIII, limited channel home sleep study) followed by PSG if needed, and an initial LIII approach followed by LII if needed. Costs per patient assessed was calculated as a function of pretest OSA probability and a variety of other variables (e.g. costs of tests, failure rate of LIII/LII, sensitivity/specificity of LIII). The situation in British Columbia was used as a case study.

Results: The variation in cost per test was calculated for each algorithm as a function of the above variables. For British Columbia, initial LII was the least costly across a broad range of pretest OSA probabilities (< 0.80) while initial LIII followed by LII as needed was least costly at very high pretest probability (> 0.8). In patients with a pretest OSA probability of 0.5, costs per patient for initial PSG, initial LII, initial LIII followed by PSG, and initial LIII followed by LII were: $588, $417, $607, and $481 respectively.

Conclusions: Using a theoretical decision model, we developed a preliminary cost framework to assess the potential role of LII studies in OSA assessment. Across a broad range of patient pretest probabilities, initial LII studies may provide substantial cost advantages. LII studies might be especially useful during pandemics as they combine the extensive physiologic information characteristic of PSG with the ability to avoid in-laboratory stays. More empiric studies need to be done to test these different algorithms.

Supplementary information: The online version contains supplementary material available at 10.1186/s41606-021-00063-5.

背景:由于考虑到患者和工作人员的安全，最近的大流行使得使用实验室多导睡眠图(PSG)评估疑似阻塞性睡眠呼吸暂停(OSA)患者更具挑战性。本研究的目的是评估二级睡眠研究(LII，家中全PSG)如何利用理论决策模型用于疑似OSA的诊断算法。方法:我们研究了四种疑似OSA的诊断算法:初始PSG方法，初始LII方法，初始III级方法(LIII，有限通道家庭睡眠研究)，必要时再进行PSG，以及初始LIII方法，必要时再进行LII。评估的每位患者的成本作为测试前OSA概率和各种其他变量(如测试成本、LIII/LII的失败率、LIII的敏感性/特异性)的函数来计算。不列颠哥伦比亚省的情况被用作案例研究。结果:计算了每种算法的每次测试成本变化作为上述变量的函数。在不列颠哥伦比亚省，在广泛的预测OSA概率范围内，初始LII的成本最低(0.8)。在检测前OSA概率为0.5的患者中，初始PSG、初始LII、初始LIII后PSG、初始LIII后LII的人均费用分别为:588美元、417美元、607美元和481美元。结论:使用理论决策模型，我们开发了一个初步的成本框架来评估LII研究在OSA评估中的潜在作用。在广泛的患者预测概率范围内，最初的LII研究可能提供实质性的成本优势。LII研究在大流行期间可能特别有用，因为它们结合了PSG的广泛生理信息特征和避免在实验室停留的能力。需要做更多的实证研究来测试这些不同的算法。补充信息:在线版本包含补充资料，提供地址:10.1186/s41606-021-00063-5。

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引用次数: 3

Sleep during infancy, inhibitory control and working memory in toddlers: findings from the FinnBrain cohort study 婴儿时期的睡眠，抑制控制和幼儿的工作记忆:FinnBrain队列研究的发现

Sleep Science and Practice

Pub Date : 2020-12-28 DOI: 10.1186/s41606-021-00064-4

I. Morales-Muñoz, S. Nolvi, T. Mäkelä, Eeva-Liisa Eskola, R. Korja, Michelle Fernandes, H. Karlsson, E. J. Paavonen, L. Karlsson

引用次数: 3

Energy cost of walking and functional aerobic capacity during moderate intensity exercise in adults with obstructive sleep apnea: a cross-sectional study 成人阻塞性睡眠呼吸暂停患者在中等强度运动中行走的能量消耗和功能性有氧能力:一项横断面研究

Sleep Science and Practice

Pub Date : 2020-10-19 DOI: 10.1186/s41606-021-00061-7

M. Aldhahi, S. Puri, Vivek Jain, Jeffrey E. Herrick

引用次数: 1

The anti-snoring bed - a pilot study 防打鼾床——一项初步研究

Sleep Science and Practice

Pub Date : 2020-09-08 DOI: 10.1186/s41606-020-00050-2

E. Wilhelm, Francesco Crivelli, N. Gerig, M. Kohler, R. Riener

引用次数: 1

Prevalence of high risk obstructive sleep apnoea by Berlin questionnaire in patients with hypertension: study from a tertiary care hospital 柏林问卷调查高血压患者中高危阻塞性睡眠呼吸暂停的患病率:来自三级医院的研究

Sleep Science and Practice

Pub Date : 2020-08-27 DOI: 10.1186/s41606-020-00052-0

Ozaifa Kareem, M. Tanvir, G. N. Bader

引用次数: 2

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