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Risk factors of post-anaesthesia care unit delirium in patients undergoing non-cardiac surgery in Singapore. 新加坡非心脏手术患者麻醉后监护病房谵妄的危险因素
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-12-01 DOI: 10.11622/smedj.2021129
Yuhe Ke, Sophia Chew, Edwin Seet, Wan Yi Wong, Vera Lim, Nelson Chua, Jinbin Zhang, Beatrice Lim, Vanessa Chua, Ne-Hooi Will Loh, Lian Kah Ti

Introduction: Post-anaesthesia care unit (PACU) delirium affects 5%-45% of patients after surgery and is associated with postoperative delirium and increased mortality. Up to 40% of PACU delirium is preventable, but it remains under-recognised due to a lack of awareness of its diagnosis. The nursing delirium screening scale (Nu-DESC) has been validated for diagnosing PACU delirium, but is not routinely used locally. This study aimed to use Nu-DESC to establish the incidence and risk factors of PACU delirium in patients undergoing non-cardiac surgery in the surgical population.

Methods: We conducted an audit of eligible patients undergoing major surgery in three public hospitals in Singapore over 1 week. Patients were assessed for delirium 30-60 min following their arrival in PACU using Nu-DESC, with a total score of ≥2 indicative of delirium.

Results: A total of 478 patients were assessed. The overall incidence rate of PACU delirium was 18/478 (3.8%), and the incidence was 9/146 (6.2%) in patients aged > 65 years. Post-anaesthesia care unit delirium was more common in females, patients with malignancy and those who underwent longer operations. Logistic regression analysis showed that the use of bispectral index (P < 0.001) and the presence of malignancy (P < 0.001) were significantly associated with a higher incidence of PACU delirium.

Conclusion: In this first local study, the incidence of PACU delirium was 3.8%, increasing to 6.2% in those aged > 65 years. Understanding these risk factors will form the basis for which protocols can be established to optimise resource management and prevent long-term morbidities and mortality in PACU delirium.

麻醉后护理病房(PACU)谵妄影响5%-45%的术后患者,并与术后谵妄和死亡率增加相关。高达40%的PACU谵妄是可以预防的,但由于缺乏对其诊断的认识,它仍未得到充分认识。护理谵妄筛查量表(Nu-DESC)已被证实可用于诊断PACU谵妄,但并未在局部常规使用。本研究旨在利用Nu-DESC确定外科人群非心脏手术患者PACU谵妄的发生率及危险因素。方法:我们对在新加坡三家公立医院接受大手术的合格患者进行了为期一周的审计。患者在到达PACU后30-60分钟使用Nu-DESC评估谵妄,总分≥2表示谵妄。结果:共评估478例患者。PACU谵妄的总发病率为18/478(3.8%),年龄> 65岁患者的发病率为9/146(6.2%)。麻醉后谵妄在女性、恶性肿瘤患者和手术时间较长的患者中更为常见。Logistic回归分析显示,双谱指数的使用(P < 0.001)和恶性肿瘤的存在(P < 0.001)与PACU谵妄的高发生率显著相关。结论:在第一个局部研究中,PACU谵妄的发生率为3.8%,在> 65岁的人群中增加到6.2%。了解这些风险因素将形成制定方案的基础,以优化资源管理,预防PACU谵妄的长期发病率和死亡率。
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引用次数: 1
Lessons from the Lim Lian Arn case: duty to advise and consent taking. 林连安案的教训:建议和同意的义务。
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-12-01 DOI: 10.11622/smedj.2021175
Thamotharampillai Thirumoorthy, Jiaying Shen, Jing Yan Seah
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引用次数: 0
Approach to clinically significant vascular anomalies in children. 儿童临床显著血管异常的探讨。
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-12-01 DOI: 10.11622/smedj.2021209
Raymond Reinaldo Tanugroho, Lynette Wei Yi Wee, Mark Jean Aan Koh, Jin Ho Chong

Vascular anomalies consist of tumours or malformations made up of abnormal growth or collections of blood vessels that can result in functional or cosmetic problems. While many vascular anomalies are present at birth, some do not appear until later in life, making diagnosis more challenging. Although many vascular anomalies are benign, some are associated with serious complications and may involve multiple organ systems. This article highlights the important features of clinically significant vascular anomalies to help physicians promptly identify and refer these cases to a specialised multidisciplinary team for evaluation and management. The discussion includes the various presenting complaints of vascular anomalies in children, namely, rapidly growing birthmarks, painful lesions, seizures/neurological manifestations, bleeding diathesis, cardiac/airway abnormalities and part of an overgrowth syndrome.

血管异常由肿瘤或畸形组成,由血管的异常生长或聚集组成,可导致功能或外观问题。虽然许多血管异常在出生时就存在,但有些直到生命后期才出现,这使得诊断更具挑战性。虽然许多血管异常是良性的,但也有一些与严重的并发症有关,可能涉及多个器官系统。本文强调了临床显著血管异常的重要特征,以帮助医生及时识别并将这些病例转介给专业的多学科团队进行评估和管理。讨论包括儿童血管异常的各种主诉,即快速增长的胎记,疼痛病变,癫痫/神经系统表现,出血素质,心脏/气道异常和部分过度生长综合征。
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引用次数: 0
Early mobilisation following fragility hip fracture surgery: current trends and association with discharge outcomes in a local tertiary hospital. 脆性髋部骨折手术后的早期活动:当前趋势及其与当地三级医院出院结果的关系
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-12-01 DOI: 10.11622/smedj.2021132
Shumei Tan, Aswinkumar Vasireddy

Introduction: Postoperative day 1 (POD 1) mobilisation is a key clinical indicator for the fragility hip fracture surgery population. This study aimed to evaluate the current trends of POD 1 mobilisation at our institution and to review the relationships between early mobilisation and outcomes of early functional recovery, length of stay (LOS) and discharge destination.

Methods: In this preliminary observational study, data pertaining to demographics, premorbid function, health status, injury and surgical factors, POD 1 mobilisation status and clinical outcomes of interest were retrieved from eligible patients. Patients who attained POD 1 ambulation formed the early ambulation (EA) group, while the remaining patients formed the delayed ambulation (DA) group. Data were analysed for any significant difference between the groups.

Results: One hundred and fifteen patients were included in the analysis. The rate of patients achieving at least sitting out of bed on POD 1 was 80.0% (n=92), which was comparable to the data available from international hip fracture audit databases. There were 55 (47.8%) patients in the EA group and 60 (52.5%) patients in the DA group. The EA group was approximately nine times more likely to achieve independence in ambulation at discharge compared to the DA group (adjusted odds ratio 9.20, 95% confidence interval 1.50-56.45; P = 0.016). There were observed trends of shorter LOS and more proportion of home discharge in the EA group compared to the DA group (P > 0.05).

Conclusion: This is the first local study to offer benchmark of the POD 1 mobilisation status for this population. Patients who attained POD 1 ambulation had better early functional recovery.

术后第1天(POD 1)活动是脆性髋部骨折手术人群的关键临床指标。本研究旨在评估本机构目前POD 1动员的趋势,并回顾早期动员与早期功能恢复、住院时间(LOS)和出院目的地之间的关系。方法:在这项初步观察性研究中,从符合条件的患者中检索有关人口统计学、发病前功能、健康状况、损伤和手术因素、POD 1动员状态和临床结果的数据。达到POD 1行走的患者为早期行走组(EA),其余患者为延迟行走组(DA)。对数据进行分析,看各组之间是否存在显著差异。结果:115例患者纳入分析。患者在POD 1中至少能下床的比例为80.0% (n=92),与国际髋部骨折审计数据库的数据相当。EA组55例(47.8%),DA组60例(52.5%)。与DA组相比,EA组在出院时实现独立行走的可能性约为9倍(调整优势比为9.20,95%可信区间为1.50-56.45;P = 0.016)。与DA组相比,EA组的LOS较短,出院比例较高(P > 0.05)。结论:这是第一个为该人群提供POD 1动员状况基准的本地研究。达到POD 1的患者早期功能恢复较好。
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引用次数: 0
Mindfulness and reflective practice pilot programme of Postgraduate Year 1 doctors: perceptions on impact and sustainability 研究生一年级医生的正念和反思实践试点计划:对影响和可持续性的看法
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-11-30 DOI: 10.4103/singaporemedj.smj-2021-419
Mae Yue Tan, Shuh Shing Lee, Marion Margaret Aw, Nasyitah Binte Abd Aziz, Yih Lin Lim, Suan Peen Foo, Ze Lei Tan, Andrew Anjian Sng, Yu Han Chee, Nicholas Beng Hui Ng, Jeremy Bingyuan Lin
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引用次数: 0
Burnout among COVID-19 hospital-based contact tracers in Singapore: results of a mixed-method, cross-sectional multicentre study 新加坡 COVID-19 医院接触追踪员的职业倦怠:一项混合方法横断面多中心研究的结果
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-11-30 DOI: 10.4103/singaporemedj.smj-2021-458
Ian Matthias Ng, Tzu-Jung Wong, Yong Yang, I. Venkatachalam, J. Sim, L. Wee, T. Liew, Evelyn Boon, Tong Yong Ng, Hwi Kwang Han, Diana Yuen Lan Tan
During the coronavirus disease 2019 (COVID-19) pandemic, contact tracers were under immense pressure to deliver effective and timely contact tracing, raising concerns of higher susceptibility to burnout. Our study aimed to determine burnout prevalence among hospital-based contact tracers and associated risk factors, so that interventions to reduce burnout risk could be formulated. One hundred and ninety-six active contact tracers across three hospitals within a healthcare cluster were invited to complete an anonymous online survey. To identify burntout, data such as demographics, work-related variables and contact tracing-related variables were collected using the Copenhagen Burnout Inventory. Associated factors were identified using multivariate statistics. Open-ended questions were included to understand the challenges and potential improvements through qualitative analysis. A total of 126 participants completed the survey, giving a completion rate of 64%, and almost half of these participants (42.9%) reported burnout. Protective factors included being on work-from-home arrangements (adjusted odds ratio [OR] 0.22, 95% confidence interval [CI] 0.08–0.56), perception of being well supported by their institution (adjusted OR 0.25, 95% CI 0.08–0.80) and being married (adjusted OR 0.28, 95% CI 0.12–0.64). Risk factors included having an administrative role pre–COVID-19 (adjusted OR 3.62, 95% CI 1.33–9.83). Work-related burnout was related to being activated for more than 1 day in the preceding week (unadjusted OR 3.25, 95% CI 1.33–7.94) and multiple activations in a day (unadjusted OR 3.54, 95% CI 1.44–4.41). Biggest challenges identified by participants were language barrier (62.7%), followed by workflow-related issues (42.1%). Our study demonstrated burnout and other challenges faced by a team of mostly hospital-based administrative staff redeployed on a part-time basis to ensure timely contact tracing. To mitigate burnout, we recommend choosing staff on work-from-home arrangements and ensuring adequate manpower and rostering arrangements.
在 2019 年冠状病毒病(COVID-19)大流行期间,接触追踪人员面临着及时有效地开展接触追踪工作的巨大压力,这引发了他们更容易产生职业倦怠的担忧。我们的研究旨在确定医院接触追踪人员的职业倦怠发生率及相关风险因素,从而制定降低职业倦怠风险的干预措施。 我们邀请了一个医疗集团内三家医院的 196 名活跃的联络追踪员完成匿名在线调查。为了识别职业倦怠,我们使用哥本哈根职业倦怠量表收集了人口统计学、工作相关变量和接触追踪相关变量等数据。使用多变量统计确定了相关因素。调查还包括开放式问题,以便通过定性分析了解所面临的挑战和可能的改进措施。 共有 126 名参与者完成了调查,完成率为 64%,其中近一半(42.9%)的参与者报告了职业倦怠。保护因素包括在家工作的安排(调整后的几率比[OR]0.22,95%置信区间[CI]0.08-0.56)、认为得到所在机构的良好支持(调整后的几率比0.25,95%置信区间[CI]0.08-0.80)和已婚(调整后的几率比0.28,95%置信区间[CI]0.12-0.64)。风险因素包括在COVID-19之前担任行政职务(调整后OR为3.62,95% CI为1.33-9.83)。与工作相关的倦怠与前一周被激活超过 1 天(未调整 OR 3.25,95% CI 1.33-7.94)和一天内多次激活(未调整 OR 3.54,95% CI 1.44-4.41)有关。参与者认为最大的挑战是语言障碍(62.7%),其次是工作流程相关问题(42.1%)。 我们的研究表明,为确保及时追踪联系人而重新部署的兼职行政人员团队面临着职业倦怠和其他挑战。为减轻职业倦怠,我们建议选择在家工作的员工,并确保充足的人力和轮岗安排。
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引用次数: 0
Empowering primary care in the management of toe fractures: a quality improvement project 增强基层医疗机构管理脚趾骨折的能力:质量改进项目
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-11-29 DOI: 10.4103/singaporemedj.smj-2022-019
Valerie Huali Tan, Amaris Shu Min Lim, Sky Wei Chee Koh, Jun Hao Tan, Choon Chiet Hong
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引用次数: 0
Use of deep learning model for paediatric elbow radiograph binomial classification: initial experience, performance and lessons learnt 使用深度学习模型进行儿科肘部 X 光片二项式分类:初步经验、性能和教训
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-11-29 DOI: 10.4103/singaporemedj.smj-2022-078
M. Tan, R. Y. Chua, Qiao Fan, M. Fortier, P. P. Chang
In this study, we aimed to compare the performance of a convolutional neural network (CNN)-based deep learning model that was trained on a dataset of normal and abnormal paediatric elbow radiographs with that of paediatric emergency department (ED) physicians on a binomial classification task. A total of 1,314 paediatric elbow lateral radiographs (patient mean age 8.2 years) were retrospectively retrieved and classified based on annotation as normal or abnormal (with pathology). They were then randomly partitioned to a development set (993 images); first and second tuning (validation) sets (109 and 100 images, respectively); and a test set (112 images). An artificial intelligence (AI) model was trained on the development set using the EfficientNet B1 network architecture. Its performance on the test set was compared to that of five physicians (inter-rater agreement: fair). Performance of the AI model and the physician group was tested using McNemar test. The accuracy of the AI model on the test set was 80.4% (95% confidence interval [CI] 71.8%–87.3%), and the area under the receiver operating characteristic curve (AUROC) was 0.872 (95% CI 0.831–0.947). The performance of the AI model vs. the physician group on the test set was: sensitivity 79.0% (95% CI: 68.4%–89.5%) vs. 64.9% (95% CI: 52.5%–77.3%; P = 0.088); and specificity 81.8% (95% CI: 71.6%–92.0%) vs. 87.3% (95% CI: 78.5%–96.1%; P = 0.439). The AI model showed good AUROC values and higher sensitivity, with the P-value at nominal significance when compared to the clinician group.
本研究旨在比较基于卷积神经网络(CNN)的深度学习模型与儿科急诊科(ED)医生在二项式分类任务中的表现。 我们回顾性地检索了 1,314 张儿科肘部侧位X光片(患者平均年龄为 8.2 岁),并根据注释将其分类为正常或异常(有病理)。然后将这些图像随机分为开发集(993 张图像)、第一和第二调整(验证)集(分别为 109 和 100 张图像)以及测试集(112 张图像)。使用 EfficientNet B1 网络架构在开发集上训练了一个人工智能(AI)模型。该模型在测试集上的表现与五位医生的表现进行了比较(评分者之间的一致性:尚可)。使用 McNemar 检验法测试了人工智能模型和医生组的性能。 人工智能模型在测试集上的准确率为 80.4%(95% 置信区间 [CI] 71.8%-87.3%),接收者操作特征曲线下面积 (AUROC) 为 0.872(95% CI 0.831-0.947)。在测试集上,人工智能模型与医生组相比的表现为:灵敏度 79.0% (95% CI: 68.4%-89.5%) vs. 64.9% (95% CI: 52.5%-77.3%; P = 0.088);特异度 81.8% (95% CI: 71.6%-92.0%) vs. 87.3% (95% CI: 78.5%-96.1%; P = 0.439)。 人工智能模型显示出良好的AUROC值和更高的灵敏度,与临床医生组相比,P值具有名义显著性。
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引用次数: 0
Diabetic myonecrosis in haemodialysis patients: importance of early recognition, noninvasive diagnosis and treatment 血液透析患者的糖尿病肌坏死:早期识别、无创诊断和治疗的重要性
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-11-29 DOI: 10.4103/singaporemedj.smj-2021-431
Jin Wen Rachael Nai, Jingyin Sophia Ng, Eng Kuang Lim, Claude Jeffrey Renaud, Fams Renal Medicine
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引用次数: 0
Characteristics and outcome of patients with anorexia nervosa on medical nutritional therapy: an institutional study with review of literature 接受医学营养疗法的神经性厌食症患者的特征和疗效:一项机构研究及文献综述
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-11-29 DOI: 10.4103/singaporemedj.smj-2022-062
Denise Elizabeth Shi Yun Teo, Valerie Wei Ling Teong, R. Ramachandran, Su Lin Lim, Charlotte Xianghui Lin
Eating disorders (EDs) are debilitating mental illnesses that can lead to significant medical complications from malnutrition. Eating disorders are on the rise in Asia and the prevalence is expected to increase. The aim of this study was to understand the characteristics of local patients and evaluate our current inpatient nutritional rehabilitation protocol for anorexia nervosa (AN). Retrospective descriptive data were gathered from 47 patients diagnosed with AN. Patients with admissions were further stratified according to their nutritional management based on whether they were on the AN protocol or standard hospital care. Data on their rate of weight gain, length of stay and calorie prescription were collected. Similar to previous studies, the majority of AN patients were female (96.7%). However, the age at presentation of AN in this study, as compared with previous local studies, had decreased (14 vs. 16 years). We also found that patients on the AN protocol were prescribed a higher amount of calories than those given standard care (2,700 vs. 2,317 calories). Patients on the AN protocol achieved a higher rate of weight gain per week (1.15 vs. 0.29 kg) and had a shorter length of hospital stay (23 vs. 36 days). Patients with AN appear to be presenting at a younger age. Medical stabilisation of AN patients can be achieved more quickly through a higher calorie inpatient AN treatment protocol. Future local studies examining actual calorie consumption, its effect on weight gain trajectory, severity of refeeding syndrome and time to remission will be beneficial.
进食障碍(ED)是一种使人衰弱的精神疾病,可因营养不良而导致严重的医疗并发症。饮食失调症在亚洲呈上升趋势,预计发病率还会增加。本研究旨在了解本地患者的特点,并评估我们目前针对神经性厌食症(AN)的住院营养康复方案。 研究收集了47名被诊断为厌食症患者的回顾性描述数据。根据入院患者是接受厌食症方案治疗还是接受标准医院护理,对他们的营养管理进行了进一步分层。研究还收集了体重增加率、住院时间和卡路里处方等数据。 与之前的研究相似,大多数 AN 患者为女性(96.7%)。不过,与之前的本地研究相比,本研究中 AN 患者的发病年龄有所下降(14 岁对 16 岁)。我们还发现,与接受标准治疗的患者相比,接受 AN 方案治疗的患者获得的热量更高(2,700 卡路里对 2,317 卡路里)。AN 方案的患者每周体重增加率更高(1.15 千克对 0.29 千克),住院时间更短(23 天对 36 天)。 AN患者的发病年龄似乎越来越小。通过高热量的AN住院治疗方案,可以更快地稳定AN患者的病情。未来对实际卡路里消耗量、其对体重增加轨迹的影响、反食综合征的严重程度以及缓解时间进行本地研究将是有益的。
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引用次数: 0
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