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MRI-guided neurolysis for the treatment of chronic refractory knee pain: a case report. 磁共振成像引导下的神经溶解术治疗慢性难治性膝关节疼痛:病例报告。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-12 DOI: 10.1007/s00256-024-04819-9
Alexander W Marka, Maximillian Strenzke, Kilian Weiss, Dimitrios C Karampinos, Klaus Woertler, Mirco Herbort, Nima Befrui, Tom Finck

Chronic refractory pain poses a significant challenge in knee joint pathologies, especially after exhaustion of conservative, arthroscopic, and endoprosthetic therapy options. This case report illustrates an innovative approach using MRI-assisted chemical neurolysis of a genicular nerve to manage persistent knee pain after arthroscopy. A 62-year-old male patient with chronic refractory knee pain, primarily localized at the inferomedial part of the knee, underwent high-resolution MRI to visualize the genicular nerves. This allowed for targeted ethanol-based neurolysis of the inferomedial genicular nerve. Following the procedure, the patient experienced substantial pain reduction for the follow-up duration of 4 months. The successful use of MRI-assisted chemical neurolysis offers a promising alternative treatment for patients with refractory knee pain, providing long-lasting pain relief without major side effects. This technique has the potential to improve the quality of life for patients suffering from chronic knee pain While these initial results are encouraging, it is important to note that further research, including both short-term and long-term studies, as well as randomized controlled trials, is warranted to establish the efficacy and safety of this treatment method in broader populations before it can be considered for routine incorporation into pain management practices.

慢性难治性疼痛是膝关节病变的一个重大挑战,尤其是在用尽保守、关节镜和假体内固定治疗方案之后。本病例报告展示了一种创新方法,即利用核磁共振辅助下的膝神经化学溶解术来治疗关节镜手术后的顽固性膝关节疼痛。一位 62 岁的男性患者患有慢性难治性膝关节疼痛,疼痛主要集中在膝关节内侧,他接受了高分辨率核磁共振成像检查,以观察膝状神经。这样就可以对膝内侧神经进行有针对性的乙醇神经溶解。术后,患者在 4 个月的随访期间疼痛明显减轻。核磁共振成像辅助化学神经溶解术的成功应用为难治性膝关节疼痛患者提供了一种前景广阔的替代治疗方法,可提供持久的疼痛缓解,且无重大副作用。这项技术有可能改善慢性膝关节疼痛患者的生活质量。虽然这些初步结果令人鼓舞,但必须指出的是,还需要进一步的研究,包括短期和长期研究以及随机对照试验,以确定这种治疗方法在更广泛人群中的有效性和安全性,然后才能考虑将其常规纳入疼痛治疗实践中。
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引用次数: 0
Stressed or fractured: MRI differentiating indicators of physeal injury. 受压还是骨折:骨骼损伤的 MRI 鉴别指标。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-04-01 DOI: 10.1007/s00256-024-04670-y
M Alejandra Bedoya, Diego Jaramillo, Jade Iwasaka-Neder, Tal Laor

Objective: To identify MRI findings that can indicate chronic physeal stress injury and differentiate it from acute Salter-Harris (SH) fracture of the pediatric knee or wrist.

Methods: IRB-approved retrospective study of consecutively selected knee and wrist MRIs from 32 athletes with chronic physeal stress injury and 30 children with acute SH fracture. MRI characteristics (physeal patency, physeal thickening, physeal signal intensity (SI), continuity of the zone of provisional calcification (ZPC), integrity of the periosteum and/or perichondrium, pattern of periphyseal and soft tissue edema signal, and joint effusion) were compared.

Results: Forty-eight chronic physeal stress injuries (mean age 13.1 years [8.2-17.5 years]) and 35 SH fractures (mean age 13.3 years [5.1-16.0 years]) were included. Any physeal thickening was more common with chronic stress injury (98% vs 77%, p = 0.003). Abnormal physeal SI was more common with SH fractures (91% vs 67%, p = 0.008). ZPC discontinuity strongly suggested chronic stress injury (79% vs 49%, p < 0.004). Periosteal and/or perichondrial elevation or rupture and soft tissue edema characterized most of the acute SH fractures (p < 0.001) and were seen only in 1 chronic stress injury (< 2%). While periphyseal edema was not significantly different in the two groups (p = 0.890), a joint effusion was associated with acute SH fracture (p < 0.001).

Conclusion: Chronic physeal stress injury of the pediatric knee and wrist shows higher incidence of ZPC discontinuity and focal physeal thickening compared to SH fracture, reflecting disruption in normal endochondral ossification. However, these findings can overlap in the 2 groups. Periosteal and/or perichondrial injury, soft tissue edema signal, and joint effusion strongly suggest SH fracture and are rarely present with chronic stress injury.

目的:确定可提示慢性趾骨应力损伤的核磁共振成像结果,并将其与小儿膝关节或腕关节的急性 Salter-Harris 骨折区分开来:确定可提示慢性趾骨应力损伤的磁共振成像结果,并将其与小儿膝关节或腕关节的急性Salter-Harris(SH)骨折区分开来:经 IRB 批准,对 32 名患有慢性趾骨应力损伤的运动员和 30 名患有急性 Salter-Harris 骨折的儿童连续选择的膝关节和腕关节 MRI 进行回顾性研究。比较了核磁共振成像特征(趾骨通畅性、趾骨增厚、趾骨信号强度(SI)、临时钙化区(ZPC)的连续性、骨膜和/或软骨周围的完整性、骨膜周围和软组织水肿信号模式以及关节积液):共纳入了 48 例慢性趾骨应力损伤(平均年龄 13.1 岁 [8.2-17.5 岁])和 35 例 SH 型骨折(平均年龄 13.3 岁 [5.1-16.0 岁])。任何趾骨增厚在慢性应力损伤中都更为常见(98% vs 77%,P = 0.003)。趾骨SI异常在SH骨折中更为常见(91% vs 67%,P = 0.008)。ZPC 不连续强烈提示慢性应力损伤(79% 对 49%,P=0.003):与SH骨折相比,小儿膝关节和腕关节的慢性骺端应力损伤显示出更高的ZPC不连续性和局灶性骺端增厚,反映出正常软骨内骨化的破坏。不过,这两组患者的这些发现可能会重叠。骨膜和/或软骨周围损伤、软组织水肿信号和关节积液强烈提示 SH 型骨折,而慢性应力性损伤很少出现这种情况。
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引用次数: 0
A painful mass infiltrating the quadriceps compartment of a young female. 一名年轻女性的股四头肌区出现疼痛性肿块。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-02-21 DOI: 10.1007/s00256-024-04616-4
Manit K Gundavda, Darshana Sanghvi, Nevitha Athikari, Raghuram Sekhar
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引用次数: 0
Severe metallosis following catastrophic failure of total shoulder arthroplasty - a case report. 全肩关节置换术灾难性失败后的严重金属中毒--病例报告。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-01-18 DOI: 10.1007/s00256-024-04575-w
Feyikemi O Ogunfuwa, Steven Needell, Ryan W Simovitch

Metallosis is an unusual but consequential complication arising from orthopedic hardware implantation, characterized by the deposition of metallic particles in the periprosthetic soft tissues. The incidence of metallosis associated with shoulder arthroplasties is exceptionally rare since the shoulder is not a weight-bearing joint, making it less susceptible to mechanical wear and, consequently, to conditions like particle disease and metallosis. Nevertheless, anomalous metal-on-metal interactions can develop in total shoulder arthroplasties if the polyethylene component fails due to wear, fracture, or dissociation. If left unaddressed, metallosis can incite an adverse immune-mediated local tissue response, culminating in joint destruction and adjacent soft tissues and muscle necrosis. In this case report, the diagnosis of metallosis was made in a patient with an anatomic total shoulder arthroplasty using a state-of-the-art photon counting detector CT supplemented by post-processing metal artifact reduction algorithms. This advanced imaging approach was effective in discerning the source of implant failure and in identifying manifestations of severe metallosis including osteolysis and pseudotumor formation. Advanced imaging methods can accurately characterize the severity and extent of metallosis, thereby helping guide surgical planning to mitigate serious complications associated with this condition.

金属病是骨科硬件植入引起的一种不常见但后果严重的并发症,其特点是金属颗粒沉积在假体周围软组织中。由于肩关节不是负重关节,不易受到机械磨损的影响,因此不易发生颗粒病和金属病等情况,因此与肩关节假体相关的金属病的发生率非常罕见。然而,如果聚乙烯组件因磨损、断裂或解离而失效,全肩关节置换术中就会出现金属对金属的异常相互作用。如果不及时处理,金属中毒会引发免疫介导的局部组织不良反应,最终导致关节破坏以及邻近软组织和肌肉坏死。在本病例报告中,我们使用了最先进的光子计数探测器 CT,并辅以后处理金属伪影减少算法,对一名接受解剖全肩关节置换术的患者进行了金属病诊断。这种先进的成像方法能有效辨别植入失败的源头,并识别严重金属病变的表现,包括骨溶解和假瘤形成。先进的成像方法可以准确描述金属病变的严重程度和范围,从而帮助指导手术规划,减轻与此病症相关的严重并发症。
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引用次数: 0
High prevalence of associated injuries in anterior cruciate ligament tears: A detailed magnetic resonance imaging analysis of 254 patients. 前十字韧带撕裂伴发损伤的高发率:对 254 名患者进行的详细磁共振成像分析。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-03-27 DOI: 10.1007/s00256-024-04665-9
Riccardo Cristiani, Fabian van de Bunt, Joanna Kvist, Anders Stålman

Objectives: To evaluate the type and prevalence of associated injuries by using magnetic resonance imaging (MRI) in patients with anterior cruciate ligament (ACL) tears.

Methods: Data from the Natural Corollaries and Recovery after ACL injury multicenter longitudinal cohort study were analyzed. Between May 2016 and October 2018, patients aged between 15 and 40 years, who had experienced an ACL tear within the last 6 weeks and sought medical attention at one of seven healthcare clinics in Sweden, were invited to participate. The mean time from injury to MRI was 19.6 ± 15.2 days. An orthopedic knee surgeon and a musculoskeletal radiologist reviewed all the MRI scans. The following structures were assessed: posterior cruciate ligament (PCL), medial collateral ligament (MCL) complex, lateral collateral ligament (LCL), popliteus tendon, medial meniscus (MM), lateral meniscus (LM), and cartilage. In addition, the presence of bone bruising, impaction fractures in the lateral femoral condyle (LFC) or posterolateral tibia (PLT), and Segond fractures were also assessed.  RESULTS: A total of 254 patients (48.4% males) with a mean age of 25.4 ± 7.1 years were included. The prevalence of associated injuries was as follows: PCL (0.4%), MCL {41.3% [superficial MCL and deep MCL (dMCL) 16.5%; isolated dMCL 24.8%]}, LCL (2.4%), MM (57.4%), LM (25.2%), cartilage (15.0%), bone bruising (92.9%), impaction fracture in the LFC (45.7%) and PLT (4.7%), and Segond fracture (7.5%).

Conclusions: The prevalence of associated injuries in patients with ACL tears was high. The findings reported in this study may serve as a reference tool for orthopedic surgeons and radiologists in the diagnosis of associated injuries using MRI in patients with ACL tears.

目的通过磁共振成像(MRI)评估前交叉韧带(ACL)撕裂患者相关损伤的类型和发生率:分析前交叉韧带损伤后的自然后果与恢复多中心纵向队列研究的数据。2016年5月至2018年10月期间,年龄在15岁至40岁之间、在过去6周内经历过十字韧带撕裂并在瑞典7家医疗诊所之一就诊的患者受邀参加了该研究。从受伤到接受核磁共振成像检查的平均时间为(19.6 ± 15.2)天。一名膝关节矫形外科医生和一名肌肉骨骼放射科医生对所有核磁共振扫描进行了复查。对以下结构进行了评估:后交叉韧带(PCL)、内侧副韧带(MCL)复合体、外侧副韧带(LCL)、腘绳肌腱、内侧半月板(MM)、外侧半月板(LM)和软骨。此外,还评估了是否存在骨挫伤、股骨外侧髁(LFC)或胫骨后外侧(PLT)的撞击性骨折以及 Segond 骨折。 结果:共纳入 254 名患者(48.4% 为男性),平均年龄为 25.4 ± 7.1 岁。相关损伤的发生率如下:PCL(0.4%)、MCL {41.3% [表层 MCL 和深层 MCL(dMCL)16.5%;孤立的 dMCL 24.8%]}、LCL(2.4%)、MM(57.4%)、LM(25.2%)、软骨(15.0%)、骨挫伤(92.9%)、LFC(45.7%)和 PLT(4.7%)的撞击性骨折以及 Segond 骨折(7.5%):结论:前交叉韧带撕裂患者的相关损伤发生率很高。结论:前交叉韧带撕裂患者伴发损伤的发生率较高,本研究报告的结果可作为骨科医生和放射科医生使用核磁共振成像诊断前交叉韧带撕裂患者伴发损伤的参考工具。
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引用次数: 0
Phalangeal microgeodic syndrome: a paediatric case series. 趾骨小关节综合征:儿科病例系列。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-01-20 DOI: 10.1007/s00256-024-04581-y
Jasmine Zacharias, Uday Mandalia, Jason Palman, Fatima Kagalwala, Cecil Bernard Colaco, Janani K Pillai

We present the clinical and radiological characteristics of phalangeal microgeodic syndrome in a cluster of five children during the second peak of COVID-19 pandemic in the UK. Each child presented with phalangeal swelling and erythema, prompting a comprehensive multi-disciplinary team review to analyse the clinical presentation, blood test results and imaging. The cohort's average age was 14.1 years, ranging from 10.4 to 16.6 years, with two girls and three boys. Four children experienced phalangeal involvement in the hands, whilst one was affected solely in the feet. A rheumatological work-up was performed for all. Hand X-rays performed on three children revealed distinct radiographic features like microgeodes, subperiosteal bone resorption and rarefaction in two cases. However, further MRI showed extensive changes closely correlated with the clinical signs of cutaneous vasculopathic rashes. The MRI abnormalities were notable, encompassing marrow oedema primarily affecting metaphyses and epiphyses, displaying broad transition zones. Soft tissue swelling and cortical erosions were also observed. These MRI features proved more pathognomonic in the acute clinical context. The study concluded that phalangeal microgeodic syndrome, characterised by digital swelling and erythema, might not be adequately assessed by plain X-rays. The more comprehensive MRI features, including marrow oedema and soft tissue abnormalities, appeared to be more indicative in diagnosing the condition. Considering the rarity of this syndrome and its temporal association with the COVID-19 pandemic, the study hypothesised that COVID-related thrombophilia and immune-mediated vasculopathy might act as crucial triggers for the active bony manifestations seen in this syndrome. KEY POINTS: • PMS is a rare, predominantly paediatric condition, of unknown aetiology which affects the digits. • Laboratory investigations are generally negative; however, in the appropriate clinical context, the X-ray findings of microgeodes and pattern of bone marrow oedema seen on MRI are pathognomonic. • Considering the rarity of PMS and temporal association with the COVID-19 pandemic, COVID vasculopathy may represent a previously unrecognised aetiology for PMS.

我们介绍了在英国 COVID-19 大流行的第二个高峰期,一组五名儿童趾骨小关节综合征的临床和放射学特征。每名儿童均出现趾骨肿胀和红斑,促使多学科团队对其进行全面复查,分析临床表现、血液化验结果和影像学检查。患儿的平均年龄为 14.1 岁,从 10.4 岁到 16.6 岁不等,其中有两名女孩和三名男孩。四名儿童的手部趾骨受累,一名儿童仅足部受累。所有患儿都接受了风湿病检查。三名患儿的手部 X 光片显示出明显的放射学特征,如微结节、骨膜下骨吸收和两个病例的骨质稀疏。然而,进一步的核磁共振成像却显示出与皮肤血管病性皮疹的临床症状密切相关的广泛变化。核磁共振成像异常非常明显,包括骨髓水肿,主要影响骨骺和骨骺,显示出广泛的过渡区。此外,还观察到软组织肿胀和皮质侵蚀。这些核磁共振成像特征在急性临床情况下被证明更具诊断意义。研究认为,以数字肿胀和红斑为特征的趾骨小关节综合征可能无法通过普通X光片进行充分评估。更全面的核磁共振成像特征,包括骨髓水肿和软组织异常,似乎更能说明病情。考虑到该综合征的罕见性及其与 COVID-19 大流行的时间关联性,研究假设 COVID 相关的血栓性疾病和免疫介导的血管病变可能是该综合征中出现的活动性骨骼表现的关键诱因。要点:- PMS是一种罕见的、主要是儿科疾病,病因不明,主要影响手指。- 实验室检查通常呈阴性,但在适当的临床情况下,X 射线检查发现的微小结节和核磁共振成像上看到的骨髓水肿模式具有病理诊断意义。- 考虑到PMS的罕见性以及与COVID-19大流行的时间关联性,COVID血管病变可能是PMS的一种以前未被发现的病因。
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引用次数: 0
Extremity radiographs derived from low-dose ultra-high-resolution CT: a phantom study. 从低剂量超高分辨率 CT 导出的四肢放射影像:一项模型研究。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-02-03 DOI: 10.1007/s00256-024-04600-y
Andrew M Hernandez, Christopher O Bayne, Cyrus Bateni, Ramit Lamba, John M Boone

Objective: To demonstrate the potential of low-dose ultra-high-resolution CT (UHRCT) images to generate high-quality radiographic images on extremity phantoms and to estimate the radiation dose required for this.

Materials and methods: A hand and knee phantom containing real human bones was imaged on an UHRCT scanner at full-dose, half-dose, and quarter-dose levels using a high-resolution extremity protocol. The raw data was reconstructed using both filtered back projection (FBP) and an iterative reconstruction algorithm (AIDR3D). Using custom designed software, each CT volume data set was converted to attenuation coefficients, and then a synthesized radiograph (synDX) was generated by forward projecting the volume data sets from a point source onto a 2D synthetic detector. The signal-to-noise ratio (SNR) was measured in the synDXs across all dose levels and the root-mean-squared error (RMSE) was computed with the FD synDXs as the reference.

Results: The proposed workflow generates high-quality synDXs at any arbitrary angle. For FBP, the SNR largely tracked with the radiation dose levels for both the knee and hand phantoms. For the knee phantom, iterative reconstruction provided a 6.1% higher SNR when compared to FBP. The RMSE was overall higher for the lowest dose levels and monotonically decreased with increasing dose. No substantial differences were observed qualitatively in the visualization of skeletal detail of the phantoms.

Conclusion: The fine detail provided by UHRCT acquisitions of extremities facilitates the ability to generate quality radiographs, potentially eliminating the need for additional scanning on a conventional digital radiography system.

目的证明低剂量超高分辨率 CT(UHRCT)图像在四肢模型上生成高质量放射图像的潜力,并估算为此所需的辐射剂量:在 UHRCT 扫描仪上使用高分辨率四肢协议,以全剂量、半剂量和四分之一剂量水平对包含真实人体骨骼的手部和膝部模型进行成像。原始数据采用滤波背投影(FBP)和迭代重建算法(AIDR3D)进行重建。使用定制软件,将每个 CT 容积数据集转换为衰减系数,然后将点源的容积数据集正向投影到二维合成探测器上,生成合成放射图像(synDX)。测量了所有剂量水平的合成放射图像的信噪比(SNR),并以 FD 合成放射图像为参照计算了均方根误差(RMSE):结果:建议的工作流程可在任意角度生成高质量的同步数据交换。对于 FBP,膝关节和手部模型的信噪比与辐射剂量水平基本一致。对于膝关节模型,迭代重建的信噪比比 FBP 高 6.1%。最低剂量水平的 RMSE 值总体较高,并随着剂量的增加而单调降低。在模型骨骼细节的可视化方面,没有观察到实质性的差异:结论:UHRCT 采集的四肢图像细节细腻,有助于生成高质量的射线照片,可能无需在传统的数字射线摄影系统上进行额外的扫描。
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引用次数: 0
Performance of thoracic ultrasonography compared with chest radiography for the detection of rib fractures using computed tomography as a reference standard. 以计算机断层扫描为参考标准,比较胸部超声波与胸部放射摄影在检测肋骨骨折方面的性能。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-03-19 DOI: 10.1007/s00256-024-04658-8
Evangelia E Vassalou, Iraklis Perysinakis, Michail E Klontzas, Eelco de Bree, Apostolos H Karantanas

Objective: Although there is growing evidence that ultrasonography is superior to X-ray for rib fractures' detection, X-ray is still indicated as the most appropriate method. This has partially been attributed to a lack of studies using an appropriate reference modality. We aimed to compare the diagnostic accuracy of ultrasonography and X-ray in the detection of rib fractures, considering CT as the reference standard.

Materials and methods: Within a 2.5-year period, all consecutive patients with clinically suspected rib fracture(s) following blunt chest trauma and available posteroanterior/anteroposterior X-ray and thoracic CT were prospectively studied and planned to undergo thoracic ultrasonography, by a single operator. All imaging examinations were evaluated for cortical rib fracture(s), and their location was recorded. The cartilaginous rib portions were not assessed. CTs and X-rays were evaluated retrospectively. Concomitant thoracic/extra-thoracic injuries were assessed on CT. Comparisons were performed with the Mann-Whitney U test and Fisher's exact test.

Results: Fifty-nine patients (32 males, 27 females; mean age, 53.1 ± 16.6 years) were included. CT, ultrasonography, and X-ray (40 posteroanterior/19 anteroposterior views) diagnosed 136/122/42 rib fractures in 56/54/27 patients, respectively. Ultrasonography and X-ray had sensitivity of 100%/40% and specificity of 89.7%/30.9% for rib fractures' detection. Ultrasound accuracy was 94.9% compared to 35.4% for X-rays (P < .001) in detecting individual rib fractures. Most fractures involved the 4th-9th ribs. Upper rib fractures were most commonly overlooked on ultrasonography. Thoracic cage/spine fractures and haemothorax represented the most common concomitant injuries.

Conclusion: Ultrasonography appeared to be superior to X-ray for the detection of rib fractures with regard to a reference CT.

目的:尽管越来越多的证据表明,超声波检查在肋骨骨折的检测中优于 X 光检查,但 X 光检查仍被认为是最合适的方法。部分原因是缺乏使用适当参考模式的研究。我们将 CT 作为参考标准,旨在比较超声波和 X 光在检测肋骨骨折方面的诊断准确性:在 2.5 年的时间里,我们对所有在胸部钝性创伤后临床疑似肋骨骨折的连续患者进行了前瞻性研究,并计划由一名操作员进行胸部超声波检查。所有造影检查都对肋骨皮质骨折进行了评估,并记录了骨折位置。软骨肋骨部分未作评估。对 CT 和 X 光片进行回顾性评估。同时进行的胸廓/胸廓外损伤通过 CT 进行评估。比较采用 Mann-Whitney U 检验和 Fisher's 精确检验:共纳入 59 名患者(32 名男性,27 名女性;平均年龄为 53.1 ± 16.6 岁)。CT、超声波和 X 光(40 个后正位切面/19 个前正位切面)分别诊断出 56/54/27 例患者的 136/122/42 根肋骨骨折。超声波和 X 光检查对肋骨骨折检测的敏感性分别为 100%/40%,特异性分别为 89.7%/30.9%。超声检查的准确率为 94.9%,而 X 光检查的准确率为 35.4%(P 结论:超声检查似乎比 X 光检查更准确:与参考 CT 相比,超声波检查在检测肋骨骨折方面似乎优于 X 光检查。
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引用次数: 0
Recurrent benign fibrous histiocytoma of the bone benefits from denosumab followed by malignant transformation: a case report. 复发性骨良性纤维组织细胞瘤受益于地诺单抗后发生恶性转化:病例报告。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-02-19 DOI: 10.1007/s00256-024-04610-w
Wetterwald Laureline, Omoumi Patrick, Nguyen Tu, Cherix Stephane, Dolcan Ana, Ferraro Daniela, Saglietti Chiara, Letovanec Igor, Digklia Antonia

Benign fibrous histiocytoma of the bone (BFHB) is a rare mesenchymal tumor, representing less than 1% of all benign bone tumors. This controversial entity is characterized by a mixture of fibroblasts arranged in a storiform pattern, varying amounts of osteoclast-type giant cells and foamy macrophages. Curettage or simple resection is usually curative. However, it was reported that up to 11% of the patients suffer from relapse. Here, we report a case of malignant transformation of BFHB after long-lasting disease stabilization under denosumab therapy.

良性骨纤维组织细胞瘤(BFHB)是一种罕见的间叶肿瘤,在所有良性骨肿瘤中占比不到 1%。这种有争议的肿瘤的特征是成纤维细胞、不同数量的破骨细胞型巨细胞和泡沫状巨噬细胞混合排列成storiform模式。刮宫或简单切除通常可以治愈。然而,据报道,多达 11% 的患者会复发。在此,我们报告了一例在接受地诺单抗治疗后病情长期稳定的 BFHB 恶性转化病例。
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引用次数: 0
Bone Density Screening Rates Among Medicare Beneficiaries: An Analysis with a focus on Asian Americans. 医疗保险受益人的骨密度筛查率:以亚裔美国人为重点的分析。
IF 1.9 3区 医学 Q2 ORTHOPEDICS Pub Date : 2024-11-01 Epub Date: 2024-03-09 DOI: 10.1007/s00256-024-04643-1
Soterios Gyftopoulos, Casey E Pelzl, Madalena Da Silva Cardoso, Juliana Xie, Simona C Kwon, Connie Y Chang

Purpose: To report osteoporosis screening utilization rates among Asian American (AsA) populations in the USA.

Methods: We retrospectively assessed the use of dual-energy X-ray absorptiometry (DXA) screening using the Medicare 5% Research Identifiable Files. Using Current Procedural Terminology (CPT) codes indicative of a DXA scan, we identified patients recommended for DXA screening according to the ACR-SPR-SSR Practice Parameters (females ≥ 65 years, males ≥ 70 years). Sociodemographic factors and their association with screening were evaluated using chi-square tests.

Results: There were 80,439 eligible AsA beneficiaries, and 12,102 (15.1%) received osteoporosis screening. DXA rate for women was approximately four times greater than the rate for men (19.8% vs. 5.0%; p < 0.001). AsA beneficiaries in zip codes with higher mean household income (MHI) were more likely to have DXA than those in lower MHI areas (17.6% vs. 14.3%, p < 0.001). AsA beneficiaries aged < 80 were more likely to receive DXA (15.5%) than those aged ≥ 80 (14.1%, p < 0.001). There were 2,979,801 eligible non-AsA beneficiaries, and 496,957 (16.7%) received osteoporosis screening during the study period. Non-Hispanic white beneficiaries had the highest overall screening rate (17.5%), followed by North American Native (13.0%), Black (11.8%), and Hispanic (11.1%) beneficiaries. Comparing AsA to non-AsA populations, there were significantly lower DXA rates among AsA beneficiaries when controlling for years of Medicare eligibility, patient age, sex, location, and mean income (p < 0.001).

Conclusion: We found lower than expected DXA screening rates for AsA patients. A better understanding of the barriers and facilitators to AsA osteoporosis screening is needed to improve patient care.

目的:报告美国亚裔美国人(AsA)骨质疏松症筛查的使用率:我们利用医疗保险 5% 研究可识别档案对双能 X 光吸收测定法 (DXA) 筛查的使用情况进行了回顾性评估。我们使用当前程序术语(CPT)代码指示 DXA 扫描,根据 ACR-SPR-SSR 实践参数(女性≥ 65 岁,男性≥ 70 岁)确定了建议进行 DXA 筛查的患者。采用卡方检验评估了社会人口学因素及其与筛查的关系:共有 80,439 名符合条件的 AsA 受益人,其中 12,102 人(15.1%)接受了骨质疏松症筛查。女性接受 DXA 检查的比例约为男性的四倍(19.8% 对 5.0%;P 结论:我们发现女性接受 DXA 检查的比例低于预期:我们发现,ASA 患者的 DXA 筛查率低于预期。需要更好地了解AsA骨质疏松症筛查的障碍和促进因素,以改善患者护理。
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Skeletal Radiology
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