Xuefang Yan, Zhu Haibo, Wang Ye, Wang Xinlong, Zhang Zhiye, Lin Yang
The kinetics of the forward extraction of aluminum ion had been investigated using Lewis cells. The influences of the aluminum concentration, temperature, and interfacial area were studied. The extracted species was demonstrated to be AlL3·(HL)3 by stoichiometry studies and the mechanism of the extraction was explained. The results indicated that the extraction process was under mixed-control by the extraction reaction at the interface and the diffusion of the resultant in the organic phase. The activation energy was calculated to be 23.26 kJ/mol and was concordant with the mixed-control regime. Further analysis suggested that the reaction orders with respect to aluminum and extractant were 1 and 2, respectively, and the extraction rate constant was 10−4.526 L2·g−2·s−1. The total rate of the extraction reaction for AlL3·(HL)3 was given based on kinetic steps.
{"title":"Kinetics and Mechanism on Removal of Aluminum from Phosphoric Medium by Solvent Extraction using Lewis Cells","authors":"Xuefang Yan, Zhu Haibo, Wang Ye, Wang Xinlong, Zhang Zhiye, Lin Yang","doi":"10.15261/SERDJ.28.95","DOIUrl":"https://doi.org/10.15261/SERDJ.28.95","url":null,"abstract":"The kinetics of the forward extraction of aluminum ion had been investigated using Lewis cells. The influences of the aluminum concentration, temperature, and interfacial area were studied. The extracted species was demonstrated to be AlL3·(HL)3 by stoichiometry studies and the mechanism of the extraction was explained. The results indicated that the extraction process was under mixed-control by the extraction reaction at the interface and the diffusion of the resultant in the organic phase. The activation energy was calculated to be 23.26 kJ/mol and was concordant with the mixed-control regime. Further analysis suggested that the reaction orders with respect to aluminum and extractant were 1 and 2, respectively, and the extraction rate constant was 10−4.526 L2·g−2·s−1. The total rate of the extraction reaction for AlL3·(HL)3 was given based on kinetic steps.","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The extraction of Fe(III), Al(III), Zn(II), Pb(II), Cu(II) and Hg(II) from hydrochloric acid leaching solution of fly ash by using solvent extraction with 25% (v/v) tributyl phosphate (TBP), 35% (v/v) 2-octanol and 40% (v/v) kerosene was investigated. To achieve the separation of Fe(III) from Al(III), Zn(II), Pb(II), Cu(II) and Hg(II), five-stage counter-current batch simulation test was conducted under the conditions of O/A = 2/1, 25 ̊C, 5min, 3.66 mol/L of HCl, resulting in the extraction efficiencies of Fe(III) as 99.86%; and the separation coefficients, e.g. βFe/Al, βFe/Zn, βFe/Pb, βFe/Cu, βFe/Hg were ~∞, 1.7 × 104, 1.8 × 104, 2.1 × 104, 6.7 × 103, respectively; in addition, over 99.9% of Fe(III) could be stripped in a six-stage counter-current batch simulation test using 0.1 mol/L HCl. The mechanism of Fe(III) extraction using tributyl phosphate and 2octanol was discussed according to FT-IR spectra results.
{"title":"Separation of Fe(III) and Al via Tributyl Phosphate and 2-Octanol in the Comprehensive Recovery Process of Metals from Hydrochloric Acid Leaching Solution of Fly Ash","authors":"Zhou Xiaozhou, Yujun Shen, Peng Jun, Liu Qiang","doi":"10.15261/SERDJ.28.59","DOIUrl":"https://doi.org/10.15261/SERDJ.28.59","url":null,"abstract":"The extraction of Fe(III), Al(III), Zn(II), Pb(II), Cu(II) and Hg(II) from hydrochloric acid leaching solution of fly ash by using solvent extraction with 25% (v/v) tributyl phosphate (TBP), 35% (v/v) 2-octanol and 40% (v/v) kerosene was investigated. To achieve the separation of Fe(III) from Al(III), Zn(II), Pb(II), Cu(II) and Hg(II), five-stage counter-current batch simulation test was conducted under the conditions of O/A = 2/1, 25 ̊C, 5min, 3.66 mol/L of HCl, resulting in the extraction efficiencies of Fe(III) as 99.86%; and the separation coefficients, e.g. βFe/Al, βFe/Zn, βFe/Pb, βFe/Cu, βFe/Hg were ~∞, 1.7 × 104, 1.8 × 104, 2.1 × 104, 6.7 × 103, respectively; in addition, over 99.9% of Fe(III) could be stripped in a six-stage counter-current batch simulation test using 0.1 mol/L HCl. The mechanism of Fe(III) extraction using tributyl phosphate and 2octanol was discussed according to FT-IR spectra results.","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Strength of axial mixing in the emulsion phase during the progress of extraction was evaluated using the Peclet number under various flow conditions. The Peclet numbers were determined with the established tracer technology which applies inert species for iodine extraction. Very little effect of operating velocities of either aqueous and organic phases was found on the Peclet numbers. This fact indicates that an almost constant degree of axial mixing was kept in this column for different flow velocities of both phases. Furthermore, the degree of axial mixing of the emulsion-flow column was compared with conventional spray and packed columns by plotting the droplet Peclet number against the droplet Reynolds number. Points of the Peclet numbers of emulsion-flow column located in the middle of the spray and the packed columns, which suggests that the strength of axial mixing in the present column is in between spray and packed columns.
{"title":"Axial Mixing in Emulsion-flow Column under Iodine Extraction","authors":"Mikiro Hirayama, T. Goshima, K. Mizuta, S. Nii","doi":"10.15261/SERDJ.28.11","DOIUrl":"https://doi.org/10.15261/SERDJ.28.11","url":null,"abstract":"Strength of axial mixing in the emulsion phase during the progress of extraction was evaluated using the Peclet number under various flow conditions. The Peclet numbers were determined with the established tracer technology which applies inert species for iodine extraction. Very little effect of operating velocities of either aqueous and organic phases was found on the Peclet numbers. This fact indicates that an almost constant degree of axial mixing was kept in this column for different flow velocities of both phases. Furthermore, the degree of axial mixing of the emulsion-flow column was compared with conventional spray and packed columns by plotting the droplet Peclet number against the droplet Reynolds number. Points of the Peclet numbers of emulsion-flow column located in the middle of the spray and the packed columns, which suggests that the strength of axial mixing in the present column is in between spray and packed columns.","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characterization of Water/Organic Biphasic System in Liquid-Liquid Slug Flow under Hydrothermal Conditions: Solvation, Vorticity, and Hydrophobicity","authors":"T. Shimanouchi, Satoko Fujioka, Tatsuya Tanifuji, Kenta Yamamoto, Koichi Terasaka, Y. Kimura","doi":"10.15261/SERDJ.28.21","DOIUrl":"https://doi.org/10.15261/SERDJ.28.21","url":null,"abstract":"Toshinori SHIMANOUCHI1, Satoko FUJIOKA2, Tatsuya TANIFUJI1, Kenta YAMAMOTO1, Koichi TERASAKA2 and Yukitaka KIMURA1,* 1Graduate School of Environmental and Life Science, Okayama University, 3-1-1 Tsushimanaka, kita-ku, Okayama, Okayama 700-8530; 2Department of Applied Chemistry, Keio University, 3-14-1 Hiyoshi, Kouhoku-ku, Yokohama, Kanagawa 223-8522 (Received February 12, 2020; Accepted May 18, 2020)","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Sasaki, Keisuke Morita, Y. Kitatsuji, Ito Keisuke, K. Yoshizuka
High concentration of Cs is present in high-level radioactive waste. It is well-known that Cs is an alkali element and difficult to extract completely into an organic phase. Crown ether compounds are widely available for Cs extractants; DtBuDB18C6 (di-t-butyl-dibenzo-18crown6), was used in this study. Organic solvents used for the industrial applications, such as n-dodecane and 1-octanol, have low solubility concerning the compound; other solvents were employed and tested. In this study, ketone-, ether-, and estertype solvents showed high solubility for DtBuDB18C6 and DtBuDB18C6, when dissolved in ketones and alcohols, exhibited relatively high Cs distribution ratios (D(Cs)), closely to 10.
{"title":"Solvent Extraction of Cesium Using DtBuDB18C6 into Various Organic Solvents","authors":"Y. Sasaki, Keisuke Morita, Y. Kitatsuji, Ito Keisuke, K. Yoshizuka","doi":"10.15261/SERDJ.28.121","DOIUrl":"https://doi.org/10.15261/SERDJ.28.121","url":null,"abstract":"High concentration of Cs is present in high-level radioactive waste. It is well-known that Cs is an alkali element and difficult to extract completely into an organic phase. Crown ether compounds are widely available for Cs extractants; DtBuDB18C6 (di-t-butyl-dibenzo-18crown6), was used in this study. Organic solvents used for the industrial applications, such as n-dodecane and 1-octanol, have low solubility concerning the compound; other solvents were employed and tested. In this study, ketone-, ether-, and estertype solvents showed high solubility for DtBuDB18C6 and DtBuDB18C6, when dissolved in ketones and alcohols, exhibited relatively high Cs distribution ratios (D(Cs)), closely to 10.","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The crystallization of the palladium(II) complex with 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol (HL) at the liquid-liquid interface was investigated in the heptane-toluene mixture/water system. Interfacial crystallization of PdLCl did not occur in the heptane/water system, whereas it occurred in the heptane-toluene mixture/water system. The crystal size distribution of PdLCl formed at the liquid-liquid interface strongly depended on the PdLCl solubility in the organic phase and the formation rate. Larger PdLCl crystals formed at the liquid-liquid interface under the higher toluene ratio, higher Pd(II) concentration and lower pH conditions.
{"title":"Crystallization of Palladium(II)-Pyridylazophenol Complex at the Liquid-Liquid Interface","authors":"A. Ohashi, Takafusa Kiminarita","doi":"10.15261/SERDJ.28.133","DOIUrl":"https://doi.org/10.15261/SERDJ.28.133","url":null,"abstract":"The crystallization of the palladium(II) complex with 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol (HL) at the liquid-liquid interface was investigated in the heptane-toluene mixture/water system. Interfacial crystallization of PdLCl did not occur in the heptane/water system, whereas it occurred in the heptane-toluene mixture/water system. The crystal size distribution of PdLCl formed at the liquid-liquid interface strongly depended on the PdLCl solubility in the organic phase and the formation rate. Larger PdLCl crystals formed at the liquid-liquid interface under the higher toluene ratio, higher Pd(II) concentration and lower pH conditions.","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A protein extraction and separation has been reported using the ionic liquid (IL)-based aqueous two-phase system (ATPS). Although ILs have many benefits, there was a problem of unfavorable physical properties such as high viscosity, or high-cost production of ILs. Recently protic ionic liquids (PILs) are emerging as an alternative to conventional ionic liquids. PILs are easily produced through a reaction between Brønsted acid and base at a relatively low cost. In this study, PILs (pyrrolidinium formate [Pyrr][HCOO] and propionate [Pyrr][C 2 H 5 COO] and inorganic salts (K 3 PO 4 , K 2 HPO 4 ) as phase-forming constituents of ATPS, were used for the protein extraction. From the binodal experiments, the phase separation abilities are [Pyrr][HCOO] > [Pyrr][C 2 H 5 COO] and K 3 PO 4 > K 2 HPO 4 . Because proteins precipitated at the interface when using K 3 PO 4 , ATPS composed of [Pyrr][HCOO] and K 2 HPO 4 was selected for the protein extraction. The proteins were successfully extracted to PIL-rich phase. The distribution ratio of each protein was in the order hemoglobin < cytochrome C < chymotrypsin < albumin. The partition behavior of proteins in PIL-based ATPS was complex and influenced by combined effect of hydrophobic, electrostatic interactions and salting out. FT-IR spectroscopic characterization indicated that secondary structures of hemoglobin and cytochrome C were retained in PIL-rich phase after
{"title":"Extraction of Proteins with Aqueous Two-Phase Systems Formed by Protic Ionic Liquids and Inorganic Salts","authors":"M. Matsumoto, Fumiya Shinji, Y. Tahara","doi":"10.15261/SERDJ.28.141","DOIUrl":"https://doi.org/10.15261/SERDJ.28.141","url":null,"abstract":"A protein extraction and separation has been reported using the ionic liquid (IL)-based aqueous two-phase system (ATPS). Although ILs have many benefits, there was a problem of unfavorable physical properties such as high viscosity, or high-cost production of ILs. Recently protic ionic liquids (PILs) are emerging as an alternative to conventional ionic liquids. PILs are easily produced through a reaction between Brønsted acid and base at a relatively low cost. In this study, PILs (pyrrolidinium formate [Pyrr][HCOO] and propionate [Pyrr][C 2 H 5 COO] and inorganic salts (K 3 PO 4 , K 2 HPO 4 ) as phase-forming constituents of ATPS, were used for the protein extraction. From the binodal experiments, the phase separation abilities are [Pyrr][HCOO] > [Pyrr][C 2 H 5 COO] and K 3 PO 4 > K 2 HPO 4 . Because proteins precipitated at the interface when using K 3 PO 4 , ATPS composed of [Pyrr][HCOO] and K 2 HPO 4 was selected for the protein extraction. The proteins were successfully extracted to PIL-rich phase. The distribution ratio of each protein was in the order hemoglobin < cytochrome C < chymotrypsin < albumin. The partition behavior of proteins in PIL-based ATPS was complex and influenced by combined effect of hydrophobic, electrostatic interactions and salting out. FT-IR spectroscopic characterization indicated that secondary structures of hemoglobin and cytochrome C were retained in PIL-rich phase after","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mochmad L. Firmansyah, A. Fajar, R. Mukti, Thalabul Ilmi, G. Kadja, M. Goto
Mochmad L. FIRMANSYAH1,*, Adroit T. N. FAJAR2, Rino R. MUKTI3,4,5, Thalabul ILMI3, Grandprix T. M. KADJA3,4,6 and Masahiro GOTO2,* 1Nanotechnology Engineering, School of Advanced Science and Multidisciplinary, Airlangga University, Jl. Dr. Ir. H. Soekarno, Surabaya 60115, Indonesia; 2Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan; 3Division of Inorganic and Physical Chemistry, Faculty of Mathematics and Natural Science, Institut Teknologi Bandung, Jl Ganesha 10, Bandung 40132, Indonesia; 4Research Center for Nanoscience and Nanotechnology, Institut Teknologi Bandung, Jl Ganesha 10, Bandung 40132, Indonesia; 5Research and Innovation Center for Advanced Materials, Institut Teknologi Sumatera, Jl. Terusan Ryacudu, Lampung 35365, Indonesia; 6Center for Catalysis and Reaction Engineering, Institut Teknologi Bandung, Jalan Ganesha no. 10, Bandung, 40132, Indonesia. (Received August 25, 2020; Accepted October 1, 2020)
Mochmad L. FIRMANSYAH1，*， Adroit T. N. FAJAR2, Rino R. mukti3,4,5, Thalabul ILMI3, Grandprix T. M. kadja3,4,6, Masahiro GOTO2，* 1纳米技术工程，哈尔滨工业大学先进科学与多学科学院，Jl。红外博士。苏加诺，泗水60115，印度尼西亚;2九州大学工程研究生院应用化学系，日本福冈819-0395;3万隆理工大学数学与自然科学学院无机与物理化学系，甘尼萨10号，印尼万隆40132;4万隆理工学院纳米科学与纳米技术研究中心，印尼万隆40132;5日本科学技术大学新材料研究与创新中心，日本;Terusan Ryacudu，印度尼西亚楠榜35365;6万隆理工学院催化与反应工程中心，加兰甘尼沙1号;10，万隆，印尼，40132。(2020年8月25日收稿;2020年10月1日录用)
{"title":"Recovery of Cobalt and Manganese from Spent Lithium-ion Batteries using a Phosphonium-based Ionic Liquid","authors":"Mochmad L. Firmansyah, A. Fajar, R. Mukti, Thalabul Ilmi, G. Kadja, M. Goto","doi":"10.15261/SERDJ.28.79","DOIUrl":"https://doi.org/10.15261/SERDJ.28.79","url":null,"abstract":"Mochmad L. FIRMANSYAH1,*, Adroit T. N. FAJAR2, Rino R. MUKTI3,4,5, Thalabul ILMI3, Grandprix T. M. KADJA3,4,6 and Masahiro GOTO2,* 1Nanotechnology Engineering, School of Advanced Science and Multidisciplinary, Airlangga University, Jl. Dr. Ir. H. Soekarno, Surabaya 60115, Indonesia; 2Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan; 3Division of Inorganic and Physical Chemistry, Faculty of Mathematics and Natural Science, Institut Teknologi Bandung, Jl Ganesha 10, Bandung 40132, Indonesia; 4Research Center for Nanoscience and Nanotechnology, Institut Teknologi Bandung, Jl Ganesha 10, Bandung 40132, Indonesia; 5Research and Innovation Center for Advanced Materials, Institut Teknologi Sumatera, Jl. Terusan Ryacudu, Lampung 35365, Indonesia; 6Center for Catalysis and Reaction Engineering, Institut Teknologi Bandung, Jalan Ganesha no. 10, Bandung, 40132, Indonesia. (Received August 25, 2020; Accepted October 1, 2020)","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The solvent extraction of single giant DNA molecular ions by N , N -dimethyl- N , N -dioctadecylammonium chloride was investigated under a fluorescence microscope with high resolution and their phase transfers from the water phase to the isooctane–1-octanol mixture (oil) phase were observed successfully. DNAs in the water phase were in the random-coil state, and those extracted in the oil phase were in the imperfect globule state, whereas those existing at the interface were almost in the globule state. From these conformation changes, the phase transfer mechanism of DNA at the interface was proposed.
{"title":"In Situ Fluorescence Microscope Measurements of the Phase Transfer Dynamics of Single DNA Molecular Ions with Dimethyldioctadecylammonium Chloride into Isooctane–1-Octanol Mixture","authors":"S. Tsukahara, Shohei Inoshita, T. Fujiwara","doi":"10.15261/SERDJ.28.1","DOIUrl":"https://doi.org/10.15261/SERDJ.28.1","url":null,"abstract":"The solvent extraction of single giant DNA molecular ions by N , N -dimethyl- N , N -dioctadecylammonium chloride was investigated under a fluorescence microscope with high resolution and their phase transfers from the water phase to the isooctane–1-octanol mixture (oil) phase were observed successfully. DNAs in the water phase were in the random-coil state, and those extracted in the oil phase were in the imperfect globule state, whereas those existing at the interface were almost in the globule state. From these conformation changes, the phase transfer mechanism of DNA at the interface was proposed.","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shinjiro Yamamoto, Yumi Kamikubo, Hiroki Tanoue, Michinari Iwasaki, S. Hayashi, H. Miyasaka
We report here the effect of increased amount of a water-immiscible ionic liquid (IL), 1-butyl-1-methylpyrrolidinium bis(trifluoromethanesulfonyl)imide (P14-TFSI), enhancing the production amount of paclitaxel with in situ extraction from an aqueous medium in a plant cell culture. The productivity of paclitaxel in the culture including the IL of 10 vol% was 1.5 times greater than that of 2.5 vol%. Moreover, addition of an elicitor, methyl jasmonate (MJ) enhanced the production amount of paclitaxel in the culture including 10% P14-TFSI. The amount of paclitaxel in the culture including 1 µM MJ and 10 vol% P14-TFSI was more than 78 times greater than those in the control culture without both P14-TFSI and MJ, and two times greater than those in the culture including 2.5 vol% P14-TFSI alone.
{"title":"Enhancement of Paclitaxel Production in Plant Cell Culture Including Increased Amount of Water-immiscible 1-Butyl-1-methylpyrrolidinium Bis(trifluoromethanesulfonyl)imide","authors":"Shinjiro Yamamoto, Yumi Kamikubo, Hiroki Tanoue, Michinari Iwasaki, S. Hayashi, H. Miyasaka","doi":"10.15261/SERDJ.28.109","DOIUrl":"https://doi.org/10.15261/SERDJ.28.109","url":null,"abstract":"We report here the effect of increased amount of a water-immiscible ionic liquid (IL), 1-butyl-1-methylpyrrolidinium bis(trifluoromethanesulfonyl)imide (P14-TFSI), enhancing the production amount of paclitaxel with in situ extraction from an aqueous medium in a plant cell culture. The productivity of paclitaxel in the culture including the IL of 10 vol% was 1.5 times greater than that of 2.5 vol%. Moreover, addition of an elicitor, methyl jasmonate (MJ) enhanced the production amount of paclitaxel in the culture including 10% P14-TFSI. The amount of paclitaxel in the culture including 1 µM MJ and 10 vol% P14-TFSI was more than 78 times greater than those in the control culture without both P14-TFSI and MJ, and two times greater than those in the culture including 2.5 vol% P14-TFSI alone.","PeriodicalId":21805,"journal":{"name":"Solvent Extraction Research and Development, Japan","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67093721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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