Pub Date : 2022-03-01DOI: 10.36303/sagp.2022.3.1.0110
Adam de Beer, W. Cordier
{"title":"Spinal revival: The management of lower back pain","authors":"Adam de Beer, W. Cordier","doi":"10.36303/sagp.2022.3.1.0110","DOIUrl":"https://doi.org/10.36303/sagp.2022.3.1.0110","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88896882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-01DOI: 10.36303/sagp.2022.3.1.0111
J. Mercier
{"title":"Permission to re-engage","authors":"J. Mercier","doi":"10.36303/sagp.2022.3.1.0111","DOIUrl":"https://doi.org/10.36303/sagp.2022.3.1.0111","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88999260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-06DOI: 10.36303/sagp.2021.2.2.0064
D. Meyersfeld
Owing to advances in genomic technology, the days of personalised medicine are truly upon us. Personalised medicine, also called precision or individualised medicine, is an evolving field of practice in which physicians use genomic information to guide the optimal course of treatment. Personalised medicine recognises the individuality of every patient who walks into a medical practice and acknowledges that each patient will require their own unique intervention to ensure optimal health outcomes.
{"title":"Genetics and its role in personalised medicine","authors":"D. Meyersfeld","doi":"10.36303/sagp.2021.2.2.0064","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.2.0064","url":null,"abstract":"Owing to advances in genomic technology, the days of personalised medicine are truly upon us. Personalised medicine, also called precision or individualised medicine, is an evolving field of practice in which physicians use genomic information to guide the optimal course of treatment. Personalised medicine recognises the individuality of every patient who walks into a medical practice and acknowledges that each patient will require their own unique intervention to ensure optimal health outcomes.","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"7 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74461196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-06DOI: 10.36303/sagp.2021.2.2.0054
R. Schoeman
According to the International Diabetes Federation (World Bank Group), the prevalence of diabetes in the adult South African population is 7.6%1 while the SASH study2 indicates the prevalence of depression in South Africa to be 9.7% with a lifetime prevalence of 16.6%. There is a bidirectional relationship between depression and diabetes, with the relative risk for diabetes being 1.6 in patients with depression, while the relative risk for depression is 1.2 in patients with diabetes (Figure 1). If controlled for all diabetes-specific risk factors, diabetes per se increases the risk of developing depression with 15%.3
{"title":"Are diabetes and depression related? Fibroblast growth factors in depression","authors":"R. Schoeman","doi":"10.36303/sagp.2021.2.2.0054","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.2.0054","url":null,"abstract":"According to the International Diabetes Federation (World Bank Group), the prevalence of diabetes in the adult South African population is 7.6%1 while the SASH study2 indicates the prevalence of depression in South Africa to be 9.7% with a lifetime prevalence of 16.6%. There is a bidirectional relationship between depression and diabetes, with the relative risk for diabetes being 1.6 in patients with depression, while the relative risk for depression is 1.2 in patients with diabetes (Figure 1). If controlled for all diabetes-specific risk factors, diabetes per se increases the risk of developing depression with 15%.3","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77746024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.36303/sagp.2021.2.2.0070
L. Moolman
Hypothyroidism is a condition characterised by the biochemical and clinical manifestations of deficient thyroid hormone concentrations. 1 Worldwide, the most common cause of this condition is iodine deficiency. In cases where iodine deficiency is not the cause, the most common causes of hypothyroidism are Hashimoto’s thyroiditis, thyroidectomy and radioactive iodine treatment. 2 Apart from thyroid gland pathology (primary hypothyroidism), hypopituitarism (secondary hypothyroidism) should also be considered. 2 Autoimmune hypothyroidism occurs at a mean annual rate of 4 per 1 000 women and 1 per 1 000 men. 2 The onset of hypothyroidism is usually insidious, and patients may only become aware of symptoms after optimal thyroid hormone replacement. Typical signs include a puffy face, oedematous eyelids, non-pitting pretibial oedema, dry, brittle hair, alopecia, thinning of the outer third of the eyebrows, pallor and retarded nail growth. 2 Goiter is sometimes the presenting symptom in Hashimoto’s thyroiditis, but typical symptoms like fatigue, dry skin, hair loss, constipation, cold intolerance and weight gain may also be present. The aim of therapy is to improve symptoms, normalise serum thyroid-stimulating hormone (TSH), reduce the goiter size and to avoid overtreatment. 3,4
{"title":"The pharmacological management of hypothyroidism","authors":"L. Moolman","doi":"10.36303/sagp.2021.2.2.0070","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.2.0070","url":null,"abstract":"Hypothyroidism is a condition characterised by the biochemical and clinical manifestations of deficient thyroid hormone concentrations. 1 Worldwide, the most common cause of this condition is iodine deficiency. In cases where iodine deficiency is not the cause, the most common causes of hypothyroidism are Hashimoto’s thyroiditis, thyroidectomy and radioactive iodine treatment. 2 Apart from thyroid gland pathology (primary hypothyroidism), hypopituitarism (secondary hypothyroidism) should also be considered. 2 Autoimmune hypothyroidism occurs at a mean annual rate of 4 per 1 000 women and 1 per 1 000 men. 2 The onset of hypothyroidism is usually insidious, and patients may only become aware of symptoms after optimal thyroid hormone replacement. Typical signs include a puffy face, oedematous eyelids, non-pitting pretibial oedema, dry, brittle hair, alopecia, thinning of the outer third of the eyebrows, pallor and retarded nail growth. 2 Goiter is sometimes the presenting symptom in Hashimoto’s thyroiditis, but typical symptoms like fatigue, dry skin, hair loss, constipation, cold intolerance and weight gain may also be present. The aim of therapy is to improve symptoms, normalise serum thyroid-stimulating hormone (TSH), reduce the goiter size and to avoid overtreatment. 3,4","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88452191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.36303/sagp.2021.2.2.0069
T. Harris, G. Viljoen
{"title":"Management of otitis externa","authors":"T. Harris, G. Viljoen","doi":"10.36303/sagp.2021.2.2.0069","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.2.0069","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"62 1","pages":"50-53"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73736240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.36303/sagp.2021.2.2.0068
H. Parkar, S. Mlambo, L. Naude, H. Strydom, N. Nakidien, A. Cromarty
{"title":"Wounds an overlooked burden (Part 3) - Chronic wounds : a conundrum of complications","authors":"H. Parkar, S. Mlambo, L. Naude, H. Strydom, N. Nakidien, A. Cromarty","doi":"10.36303/sagp.2021.2.2.0068","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.2.0068","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"26 1","pages":"58-66"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78253864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.36303/sagp.2021.2.1.0072
L. D. Beer
{"title":"Five most common reasons for bad debt and what you can do about it","authors":"L. D. Beer","doi":"10.36303/sagp.2021.2.1.0072","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.1.0072","url":null,"abstract":"","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"531 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77698335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-03DOI: 10.36303/sagp.2021.2.1.0056
K. Outhoff
The COVID-19 pandemic has accelerated unprecedented research of experimental treatments as well as using established drugs in new ways. At the end of November 2020, we reflected on the various therapies for COVID-19 that had received regulatory full or emergency use authorisation including the convalescent plasma-derived IgG1 antibodies, bamlanivimab, and the casirivimab-imdevimab cocktail, that provide passive immunity in patients with mild to moderate disease who are at risk for severe illness, the intravenous antiviral, remdesivir, for patients with severe disease requiring hospitalisation, as well as the WHO-endorsed systemic inexpensive glucocorticoids such as dexamethasone, hydrocortisone, methylprednisolone or prednisone for critically ill patients requiring oxygen.1
{"title":"COVID-19 vaccines: are we good to go?","authors":"K. Outhoff","doi":"10.36303/sagp.2021.2.1.0056","DOIUrl":"https://doi.org/10.36303/sagp.2021.2.1.0056","url":null,"abstract":"The COVID-19 pandemic has accelerated unprecedented research of experimental treatments as well as using established drugs in new ways. At the end of November 2020, we reflected on the various therapies for COVID-19 that had received regulatory full or emergency use authorisation including the convalescent plasma-derived IgG1 antibodies, bamlanivimab, and the casirivimab-imdevimab cocktail, that provide passive immunity in patients with mild to moderate disease who are at risk for severe illness, the intravenous antiviral, remdesivir, for patients with severe disease requiring hospitalisation, as well as the WHO-endorsed systemic inexpensive glucocorticoids such as dexamethasone, hydrocortisone, methylprednisolone or prednisone for critically ill patients requiring oxygen.1","PeriodicalId":21867,"journal":{"name":"South African General Practitioner","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87365644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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