Le present travail vise a determiner les teneurs de quelques constituants de la fraction insaponifiable de 13 echantillons d’huile d’olive provenant de plusieurs regions d’Algerie, tout en evaluant leurs activites antibacteriennes a l’egard de huit souches ATCC potentiellement pathogenes. La teneur en polyphenols totaux dans les echantillons a varie significativement (p < 0,05) d’un extrait a un autre, et les valeurs les plus importantes ont ete enregistrees dans les extraits de Skikda et Tissemsilt (207,97 ± 1,75 mg d’acide gallique/kg et 202,97 ± 2,67 mg d’acide gallique/kg respectivement). La teneur en flavonoides totaux dans les differents extraits etait variable. Les teneurs les plus elevees ont ete enregistrees dans les extraits d’Ain-Defla et Blida, alors que l’extrait de Jijel a ete le plus riche en flavonols, avec une valeur de 258,22 ± 13,00 mg/kg. Aucune correlation n’a ete etablie entre la teneur en polyphenols totaux et les flavonoides totaux. Les souches bacteriennes ont montre un comportement variable entre la sensibilite, l’extreme sensibilite et la resistance vis-a-vis des extraits phenoliques avec une correlation negative entre la teneur en polyphenols totaux et l’activite antibacterienne, tandis que les concentrations minimales inhibitrices les plus faibles ont ete enregistrees avec les extraits qui ont donne les diametres des zones d’inhibition les plus elevees.
{"title":"Activités antibactériennes des constituants de la fraction insaponifiable de l’huile d’olive","authors":"S. Metlef, A. Delmi-Bouras, A. Zidane, M. Benali","doi":"10.3166/PHYTO-2021-0250","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0250","url":null,"abstract":"Le present travail vise a determiner les teneurs de quelques constituants de la fraction insaponifiable de 13 echantillons d’huile d’olive provenant de plusieurs regions d’Algerie, tout en evaluant leurs activites antibacteriennes a l’egard de huit souches ATCC potentiellement pathogenes. La teneur en polyphenols totaux dans les echantillons a varie significativement (p < 0,05) d’un extrait a un autre, et les valeurs les plus importantes ont ete enregistrees dans les extraits de Skikda et Tissemsilt (207,97 ± 1,75 mg d’acide gallique/kg et 202,97 ± 2,67 mg d’acide gallique/kg respectivement). La teneur en flavonoides totaux dans les differents extraits etait variable. Les teneurs les plus elevees ont ete enregistrees dans les extraits d’Ain-Defla et Blida, alors que l’extrait de Jijel a ete le plus riche en flavonols, avec une valeur de 258,22 ± 13,00 mg/kg. Aucune correlation n’a ete etablie entre la teneur en polyphenols totaux et les flavonoides totaux. Les souches bacteriennes ont montre un comportement variable entre la sensibilite, l’extreme sensibilite et la resistance vis-a-vis des extraits phenoliques avec une correlation negative entre la teneur en polyphenols totaux et l’activite antibacterienne, tandis que les concentrations minimales inhibitrices les plus faibles ont ete enregistrees avec les extraits qui ont donne les diametres des zones d’inhibition les plus elevees.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90169812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Ouattara, A. Touré, K. J. Golly, G. M. Ahon, A. Coulibaly, K. Ouattara
Carapa procera (Meliaceae) est une plante très exploitée en médecine traditionnelle pour le traitement des pathologies infectieuses en Afrique occidentale. Le but de ce travail est d’évaluer l’activité antibactérienne de l’extrait hydroalcoolique des feuilles de cette plante sur la croissance in vitro de Staphylococcus aureus (204C12) et Shigella sp. (1177C10), deux germes multirésistants. Les paramètres antibactériens de Carapa procera ont été déterminés par les méthodes de diffusion en milieu solide et de dilution en milieu liquide respectivement pour les diamètres d’inhibition et les concentrations minimales inhibitrice et bactéricide (CMI et CMB). L’extrait de Carapa procera a montré une activité bactéricide effective avec des diamètres d’inhibition variant de 18 à 21 mm pour des CMB de 0,19 mg/ml et de 0,39 mg/ml respectivement contre Shigella sp. et Staphylococcus aureus. Le potentiel antibactérien de cet extrait pourrait être attribué aux alcaloïdes, aux tanins et aux flavonoïdes révélés par le screening phytochimique. Les résultats obtenus confirment l’utilisation traditionnelle de cette plante dans le traitement des différentes pathologies dans lesquelles les germes testés sont impliqués.
{"title":"Activité antibactérienne d’un extrait hydroalcoolique des feuilles de Carapa procera (Méliacée) sur Staphylococcus aureus et Shigella sp.","authors":"A. Ouattara, A. Touré, K. J. Golly, G. M. Ahon, A. Coulibaly, K. Ouattara","doi":"10.3166/PHYTO-2018-0104","DOIUrl":"https://doi.org/10.3166/PHYTO-2018-0104","url":null,"abstract":"Carapa procera (Meliaceae) est une plante très exploitée en médecine traditionnelle pour le traitement des pathologies infectieuses en Afrique occidentale. Le but de ce travail est d’évaluer l’activité antibactérienne de l’extrait hydroalcoolique des feuilles de cette plante sur la croissance in vitro de Staphylococcus aureus (204C12) et Shigella sp. (1177C10), deux germes multirésistants. Les paramètres antibactériens de Carapa procera ont été déterminés par les méthodes de diffusion en milieu solide et de dilution en milieu liquide respectivement pour les diamètres d’inhibition et les concentrations minimales inhibitrice et bactéricide (CMI et CMB). L’extrait de Carapa procera a montré une activité bactéricide effective avec des diamètres d’inhibition variant de 18 à 21 mm pour des CMB de 0,19 mg/ml et de 0,39 mg/ml respectivement contre Shigella sp. et Staphylococcus aureus. Le potentiel antibactérien de cet extrait pourrait être attribué aux alcaloïdes, aux tanins et aux flavonoïdes révélés par le screening phytochimique. Les résultats obtenus confirment l’utilisation traditionnelle de cette plante dans le traitement des différentes pathologies dans lesquelles les germes testés sont impliqués.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89830000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Darâa-Tafilalet is considered as one of the charming Moroccan areas concerning the knowledge connected to the traditional use of plants for a therapeutic purpose. This work aims to collect, analyze and evaluate the ethnobotanical knowledge about medicinal plants used in the management of diverse forms of cancer in the Darâa-Tafilalet region. The total number of informants interviewed in this study was 1026 (944 were ordinary local inhabitants and 82 were herbalists). Information was obtained by means of structured and semi-structured interviews with local people. Then, data obtained from interviewees were analyzed by calculating some relative cultural importance (RCI) indices (UV, FUV, ROP and FL). Principal component analysis (PCA) was also involved in this study for comparing some characteristics of species. 101 plants used in folk medicine and belonging to 47 families were identified in this study. The highest UV was attributed to Suaeda vermiculata (0.06897); while, the optimal FUV has been given to Ranunculaceae (0.05956). Concerning the FL values, Nigella sativa, Allium sativum, Allium cepa, Calotropis procera, Foeniculum vulgare and Olea europaea were classified in first with a value cited 100% all for general cancer; whereas Nigella sativa had the highest ROP value (86%). The present enquiry highlighted interesting botanical and cultural findings related to the anticancer ethnomedical knowledge adapted by the local population of Darâa-Tafilalet. However, several experimental and fieldwork studies are needed to give more validity and reliability to such investigation.
{"title":"Ethnopharmacological Survey of Medicinal Plants against Cancer in Southeastern Morocco","authors":"M. Eddouks, N. Lahrach, M. Ajebli, M. Hebi","doi":"10.3166/PHYTO-2021-0253","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0253","url":null,"abstract":"Darâa-Tafilalet is considered as one of the charming Moroccan areas concerning the knowledge connected to the traditional use of plants for a therapeutic purpose. This work aims to collect, analyze and evaluate the ethnobotanical knowledge about medicinal plants used in the management of diverse forms of cancer in the Darâa-Tafilalet region. The total number of informants interviewed in this study was 1026 (944 were ordinary local inhabitants and 82 were herbalists). Information was obtained by means of structured and semi-structured interviews with local people. Then, data obtained from interviewees were analyzed by calculating some relative cultural importance (RCI) indices (UV, FUV, ROP and FL). Principal component analysis (PCA) was also involved in this study for comparing some characteristics of species. 101 plants used in folk medicine and belonging to 47 families were identified in this study. The highest UV was attributed to Suaeda vermiculata (0.06897); while, the optimal FUV has been given to Ranunculaceae (0.05956). Concerning the FL values, Nigella sativa, Allium sativum, Allium cepa, Calotropis procera, Foeniculum vulgare and Olea europaea were classified in first with a value cited 100% all for general cancer; whereas Nigella sativa had the highest ROP value (86%). The present enquiry highlighted interesting botanical and cultural findings related to the anticancer ethnomedical knowledge adapted by the local population of Darâa-Tafilalet. However, several experimental and fieldwork studies are needed to give more validity and reliability to such investigation.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88020211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Virginian cedarwood (Juniperus virginiana L.) essential oil is an important component of a very large number of fragrances, used in cosmetics or household products. Clary sage (Salvia sclarea L.) essential oil is well known in aromatherapy for its sedative property. The essential oils of Virginian cedarwood’s crushed barks and clary sage’s leaves were analyzed by GC/MS. Respectively, seven and seventeen compounds; representing 78% and 94.13% of the essential oils, were identified. The main components of the cedar oil are cedrene alpha (25%) and cedrol (20%). The main components of the clary sage oil are linalyl acetate (69.4%) and linalool (11.9%). Cedarwood oil exhibits significant relaxing activity, influencing physiological and biochemical parameters in human. This shows repercussions on situational stress. Virginian Cedarwood essential oil activity is compared with clary sage essential oil, which proved to be less efficient on stress relief.
{"title":"Multifactorial Evaluation of Relaxing Properties of Juniperus virginiana L. Essential Oil and Comparison with Salvia sclarea L. Essential Oil","authors":"A. Pegard","doi":"10.3166/PHYTO-2021-0266","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0266","url":null,"abstract":"Virginian cedarwood (Juniperus virginiana L.) essential oil is an important component of a very large number of fragrances, used in cosmetics or household products. Clary sage (Salvia sclarea L.) essential oil is well known in aromatherapy for its sedative property. The essential oils of Virginian cedarwood’s crushed barks and clary sage’s leaves were analyzed by GC/MS. Respectively, seven and seventeen compounds; representing 78% and 94.13% of the essential oils, were identified. The main components of the cedar oil are cedrene alpha (25%) and cedrol (20%). The main components of the clary sage oil are linalyl acetate (69.4%) and linalool (11.9%). Cedarwood oil exhibits significant relaxing activity, influencing physiological and biochemical parameters in human. This shows repercussions on situational stress. Virginian Cedarwood essential oil activity is compared with clary sage essential oil, which proved to be less efficient on stress relief.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81647879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pendant la grossesse, les femmes se plaignent, le plus souvent, de nausées, de constipation, de jambes lourdes, de nervosité et d’insomnie, et parfois, d’infection urinaire, d’hémorroïdes. Les maux (de l’hiver) hivernaux, comme rhume, grippe et angine, ne les épargnent pas. Les femmes enceintes, conscientes des risques auxquels lesmédicaments les exposent, se tournent, souvent, vers des médecines dites douces comme la phytothérapie. Au Maghreb, il est facile de se procurer les plantes médicinales dont on a besoin, soit dans les boutiques des herboristes, soit au marché où les étals en offrent une très grande variété. Contrairement à une idée très répandue, la phytothérapie est loin d’être toujours inoffensive. La prudence s’impose, donc, comme avec n’importe quel médicament.
{"title":"Les plantes nocives pour la grossesse","authors":"V. Hammiche","doi":"10.3166/PHYTO-2021-0267","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0267","url":null,"abstract":"Pendant la grossesse, les femmes se plaignent, le plus souvent, de nausées, de constipation, de jambes lourdes, de nervosité et d’insomnie, et parfois, d’infection urinaire, d’hémorroïdes. Les maux (de l’hiver) hivernaux, comme rhume, grippe et angine, ne les épargnent pas. Les femmes enceintes, conscientes des risques auxquels lesmédicaments les exposent, se tournent, souvent, vers des médecines dites douces comme la phytothérapie. Au Maghreb, il est facile de se procurer les plantes médicinales dont on a besoin, soit dans les boutiques des herboristes, soit au marché où les étals en offrent une très grande variété. Contrairement à une idée très répandue, la phytothérapie est loin d’être toujours inoffensive. La prudence s’impose, donc, comme avec n’importe quel médicament.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75730879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Algerian flora is rich in medicinal plants used locally to care for many sicknesses and diseases. Ridolfia segetum is one of these plants that grows in the southwest of the country in the Saoura Bechar region. The essential oil of seeds of Ridolfia segetum was extracted by hydro distillation and analyzed by chromatography and mass spectrography (CG/MS). The obtained results show that the most important compounds are carvone (69.9%) and apiole (12.41%) as major products and dihydrocarvone (6.66%) and limonene (5.62%) and traces of perillaldehyde, dihydrocarveol, linalool, p-cymene, and β-pinene. More characteristics of the essential oil of seeds of Ridolfia segetum have been also proclaimed at the end of this paper.
{"title":"Chemical Analysis and Optimization of the Extracting Process of Essential Oil of Ridolfia segetum","authors":"Y. Adamou, M. Korichi, D. Elabed, M. S. Bennouna","doi":"10.3166/PHYTO-2021-0256","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0256","url":null,"abstract":"Algerian flora is rich in medicinal plants used locally to care for many sicknesses and diseases. Ridolfia segetum is one of these plants that grows in the southwest of the country in the Saoura Bechar region. The essential oil of seeds of Ridolfia segetum was extracted by hydro distillation and analyzed by chromatography and mass spectrography (CG/MS). The obtained results show that the most important compounds are carvone (69.9%) and apiole (12.41%) as major products and dihydrocarvone (6.66%) and limonene (5.62%) and traces of perillaldehyde, dihydrocarveol, linalool, p-cymene, and β-pinene. More characteristics of the essential oil of seeds of Ridolfia segetum have been also proclaimed at the end of this paper.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"157 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73693476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Ménadi, S. Meziani, M. Zairi, S. Bouazza, A. Demmouche, T. Djadel, K. Benabdeli, S. Belbraouet
Objectif : Le but de cette etude etait d’evaluer l’efficacite du son de ble dur riche en fibres alimentaires chez des patients adultes souffrant du syndrome de l’intestin irritable (SII).Patients et methodes : Il s’agit d’une etude prospective, incluant 40 patients soumis a un regime riche en son de ble (30 g/j). L’evaluation portait sur les criteres cliniques (poids, nombre et consistance des selles) et l’evolution des differents symptomes : constipation, diarrhee, douleurs et ballonnements.Resultats : Quarante patients ont ete inclus (15 femmes et 25 hommes). L’âge moyen est de 45,35 ± 4,3 ans, 94,90 % vivaient en famille. Une consommation de 30 g/j de son de ble riche en fibres (43,5 % MS) a entraine une augmentation tres significative du poids des selles (200, 13 ± 24,23 vs 73,80 ± 15,96 g) [p : Cette etude demontre l’efficacite du son de ble dans le traitement du syndrome de l’intestin irritable.
目的:本研究的目的是评估富含膳食纤维的硬麦麸皮对肠易激综合征(ibs)成人患者的疗效。患者和方法:这是一项前瞻性研究，包括40名患者接受富含麸皮(30 g/ d)的饮食。评估包括临床标准(粪便重量、数量和浓度)和各种症状的演变:便秘、腹泻、疼痛和腹胀。结果:纳入40例患者(女性15例，男性25例)。平均年龄45.35±4.3岁，94.90%生活在家庭中。消耗30 g / d其富含纤维的ble (MS 43.5%)将导致非常显著增加了马鞍的重量(20±13、24.23 vs 73.80±11 [p (g):这项研究他的卡托普利公费ble综合症治疗肠癌急躁。
{"title":"Effet du son de blé dur dans le traitement du syndrome de l’intestin irritable","authors":"N. Ménadi, S. Meziani, M. Zairi, S. Bouazza, A. Demmouche, T. Djadel, K. Benabdeli, S. Belbraouet","doi":"10.3166/PHYTO-2021-0254","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0254","url":null,"abstract":"Objectif : Le but de cette etude etait d’evaluer l’efficacite du son de ble dur riche en fibres alimentaires chez des patients adultes souffrant du syndrome de l’intestin irritable (SII).Patients et methodes : Il s’agit d’une etude prospective, incluant 40 patients soumis a un regime riche en son de ble (30 g/j). L’evaluation portait sur les criteres cliniques (poids, nombre et consistance des selles) et l’evolution des differents symptomes : constipation, diarrhee, douleurs et ballonnements.Resultats : Quarante patients ont ete inclus (15 femmes et 25 hommes). L’âge moyen est de 45,35 ± 4,3 ans, 94,90 % vivaient en famille. Une consommation de 30 g/j de son de ble riche en fibres (43,5 % MS) a entraine une augmentation tres significative du poids des selles (200, 13 ± 24,23 vs 73,80 ± 15,96 g) [p : Cette etude demontre l’efficacite du son de ble dans le traitement du syndrome de l’intestin irritable.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81072636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Assia Berrani, Moncef Boufellous, H. Frikh, M. Aouji, L. A. Lrhorfi̇
In the framework of the valorization of the plants of Morocco and in order to optimize the subsequent use of the plant Genista quadriflora (Fabaceae) in Morocco, extracts were prepared from the plant using solvents of increasing polarity to emphasize their antioxidant potency and antimicrobial activity. The evaluation of the antioxidant power, using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging method, indicated by qualitative analysis of the extracts either by thin layer chromatography (TLC) or by color reaction, that the extracts (aqueous and methanol) have an antioxidant effect varies between 70% and 80%. As regards the 50% inhibitory concentration (IC50) scavenging values of the DPPH radical, the two extracts showed an inhibitory activity with IC50 at around 12.5 mg/ml. The antimicrobial activity was evaluated by the agar diffusion method against Staphylococcus aureus, Escherichia coli, Candida albicans and Klebsiella pneumoniae. This evaluation showed that the methanol extracts are the most active for all the strains tested and revealed a significant antibacterial activity against Escherichia coli.
{"title":"Evaluation of the Antioxidant and Antimicrobial Activity of Genista quadriflora (G.Q) Plant Extracts","authors":"Assia Berrani, Moncef Boufellous, H. Frikh, M. Aouji, L. A. Lrhorfi̇","doi":"10.3166/PHYTO-2021-0249","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0249","url":null,"abstract":"In the framework of the valorization of the plants of Morocco and in order to optimize the subsequent use of the plant Genista quadriflora (Fabaceae) in Morocco, extracts were prepared from the plant using solvents of increasing polarity to emphasize their antioxidant potency and antimicrobial activity. The evaluation of the antioxidant power, using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging method, indicated by qualitative analysis of the extracts either by thin layer chromatography (TLC) or by color reaction, that the extracts (aqueous and methanol) have an antioxidant effect varies between 70% and 80%. As regards the 50% inhibitory concentration (IC50) scavenging values of the DPPH radical, the two extracts showed an inhibitory activity with IC50 at around 12.5 mg/ml. The antimicrobial activity was evaluated by the agar diffusion method against Staphylococcus aureus, Escherichia coli, Candida albicans and Klebsiella pneumoniae. This evaluation showed that the methanol extracts are the most active for all the strains tested and revealed a significant antibacterial activity against Escherichia coli.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84368934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The current study aims to evaluate the toxicity and the pharmacological activities of a spontaneous, medicinal and aromatic plant of the North-east of Algeria. Calendula suffruticosa subsp. suffruticosa Vahl. (Asteraceae) is widely used in traditional medicine to treat various diseases including inflammation, duodenal ulcers, burns and skin diseases. The anti-inflammatory activity of the ethanolic extract was evaluated by the inflammatory edema test induced by carrageenan in mice. And the analgesic activity has been determined in a model of pain induced by acetic acid. The diclofenac and acetylsalicylic acid are used as reference drugs. The toxicological study of the ethanolic extract revealed that the LD50 of this extract is greater than 1,000 mg/kg of body weight. The ethanolic extract at the dose 200 and 400 mg/kg administered orally and possesses a significant anti-inflammatory activity (test of Anova). The results of the analgesic activity also show the strong effect of the extract tested against chemical pain. This extract at a dose of 400 mg/kg, has analgesic activity greater to that of acetylsalicylic acid in the dose of 100 mg/kg, with a percentage inhibition of 81.13 ± 1.09%. These results confirm the anti-inflammatory and analgesic properties of Calendula suffruticosa subsp. suffruticosa Vahl., which are mainly due to the phytochemical composition of the extract studied.
{"title":"Evaluation of the Anti-inflammatory and Analgesic Activity\u0000of the Ethanolic Extract Arial Parts of Calendula suffruticosa subsp. Suffruticosa Vahl","authors":"I. Sofiane, K. Azin, R. Seridi","doi":"10.3166/PHYTO-2020-0232","DOIUrl":"https://doi.org/10.3166/PHYTO-2020-0232","url":null,"abstract":"The current study aims to evaluate the toxicity and the pharmacological activities of a spontaneous, medicinal and aromatic plant of the North-east of Algeria. Calendula suffruticosa subsp. suffruticosa Vahl. (Asteraceae) is widely used in traditional medicine to treat various diseases including inflammation, duodenal ulcers, burns and skin diseases. The anti-inflammatory activity of the ethanolic extract was evaluated by the inflammatory edema test induced by carrageenan in mice. And the analgesic activity has been determined in a model of pain induced by acetic acid. The diclofenac and acetylsalicylic acid are used as reference drugs. The toxicological study of the ethanolic extract revealed that the LD50 of this extract is greater than 1,000 mg/kg of body weight. The ethanolic extract at the dose 200 and 400 mg/kg administered orally and possesses a significant anti-inflammatory activity (test of Anova). The results of the analgesic activity also show the strong effect of the extract tested against chemical pain. This extract at a dose of 400 mg/kg, has analgesic activity greater to that of acetylsalicylic acid in the dose of 100 mg/kg, with a percentage inhibition of 81.13 ± 1.09%. These results confirm the anti-inflammatory and analgesic properties of Calendula suffruticosa subsp. suffruticosa Vahl., which are mainly due to the phytochemical composition of the extract studied.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88194331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Belkessam, S. El-Bok, M. Barhoumi, A. Mathlouthi, N. Ghanem-Boughanmi, M. Ben-Attia
{"title":"Carotte sauvage","authors":"M. Belkessam, S. El-Bok, M. Barhoumi, A. Mathlouthi, N. Ghanem-Boughanmi, M. Ben-Attia","doi":"10.3166/PHYTO-2021-0265","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0265","url":null,"abstract":"","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88475633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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