Pour notre étude, nous avons obtenu quatre fractions flavonoïques à partir de l’extrait brut de feuilles de Ballota hirsuta Benth. La séparation des flavonoïdes par chromatographie sur couche mince révèle la présence des molécules flavonoïques en particulier dans la fraction chloroformique et l’acétate d’éthyle. Les résultats de l’HPLC montrent la présence de la naringine dans la fraction n-BuOH, de la sylibine et de la taxifoline dans la fraction d’acétate. Une forte activité inhibitrice des quatre extraits a été remarquée sur Escherichia coli ATCC 25922 et Staphylococcus aureus ATCC 13565. En revanche, Pseudomonas aeruginosa ATCC 27835 s’est révélée résistante par rapport aux autres bactéries, cela est dû à la structure de sa paroi qui lui confère cette résistance. Les concentrations minimales inhibitrices varient entre 0,25 et 2 mg/ml en fonction de l’extrait flavonoïque et de la souche microbienne.
{"title":"Évaluation de l’activité antibactérienne des flavonoïdes de Ballota hirsuta Benth","authors":"K. Kechar, B. Hellal","doi":"10.3166/PHYTO-2021-0252","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0252","url":null,"abstract":"Pour notre étude, nous avons obtenu quatre fractions flavonoïques à partir de l’extrait brut de feuilles de Ballota hirsuta Benth. La séparation des flavonoïdes par chromatographie sur couche mince révèle la présence des molécules flavonoïques en particulier dans la fraction chloroformique et l’acétate d’éthyle. Les résultats de l’HPLC montrent la présence de la naringine dans la fraction n-BuOH, de la sylibine et de la taxifoline dans la fraction d’acétate. Une forte activité inhibitrice des quatre extraits a été remarquée sur Escherichia coli ATCC 25922 et Staphylococcus aureus ATCC 13565. En revanche, Pseudomonas aeruginosa ATCC 27835 s’est révélée résistante par rapport aux autres bactéries, cela est dû à la structure de sa paroi qui lui confère cette résistance. Les concentrations minimales inhibitrices varient entre 0,25 et 2 mg/ml en fonction de l’extrait flavonoïque et de la souche microbienne.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"412 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74372283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study was to evaluate the anti-inflammatory effect of the polyphenolic extract of olive leaves Olea europaea L. In vivo experiments were performed on the model of acute inflammation edema of the paw of male Wistar rats following inflammation induced by the injection of carrageenan. The anti-inflammatory effect is carried out by the injection of the polyphenolic extracts of olive leaves Olea europaea L. at different doses 50 mg/kg, 100 mg/kg and 150 mg/kg, the injection was carried out 30 min before induction of acute inflammation with carrageenan at 1%. The results obtained were compared with those of Diclofenac and those of the physiological control. Injection of carrageenan resulted in a significant increase in the claw leg volume of 46.24 ± 23.8%, 66.78 ± 29.69% and 90.31 ± 46.51%, respectively at 1 h, 2 h, and 3 h. The results showed that the inflammatory activity of the polyphenolic extracts of olive leaves was dose dependent. The 150 mg/kg Olea europaea L. extract of polyphenolic has an anti-inflammatory activity which results in an 88% decrease in edema. This decrease is significantly similar to that of Diclofenac® 97% confirmed that the polyphenolic extracts of Olea europaea L. leaves have anti-inflammatory activities comparable to that of Diclofenac® with a non-significant difference (p < 0.05), this anti-inflammatory effect remains lower than that of Diclofenac®.
{"title":"The Anti-inflammatory Effect of Polyphenolics Olive Leaf Extracts Olea europaea L.","authors":"Y. Aissaoui, Y. Boukhari, M. Mahi","doi":"10.3166/PHYTO-2021-0251","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0251","url":null,"abstract":"This study was to evaluate the anti-inflammatory effect of the polyphenolic extract of olive leaves Olea europaea L. In vivo experiments were performed on the model of acute inflammation edema of the paw of male Wistar rats following inflammation induced by the injection of carrageenan. The anti-inflammatory effect is carried out by the injection of the polyphenolic extracts of olive leaves Olea europaea L. at different doses 50 mg/kg, 100 mg/kg and 150 mg/kg, the injection was carried out 30 min before induction of acute inflammation with carrageenan at 1%. The results obtained were compared with those of Diclofenac and those of the physiological control. Injection of carrageenan resulted in a significant increase in the claw leg volume of 46.24 ± 23.8%, 66.78 ± 29.69% and 90.31 ± 46.51%, respectively at 1 h, 2 h, and 3 h. The results showed that the inflammatory activity of the polyphenolic extracts of olive leaves was dose dependent. The 150 mg/kg Olea europaea L. extract of polyphenolic has an anti-inflammatory activity which results in an 88% decrease in edema. This decrease is significantly similar to that of Diclofenac® 97% confirmed that the polyphenolic extracts of Olea europaea L. leaves have anti-inflammatory activities comparable to that of Diclofenac® with a non-significant difference (p < 0.05), this anti-inflammatory effect remains lower than that of Diclofenac®.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91123665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study was designed to evaluate the antioxidant activity of phenolic compounds of for Lamiaceae: Salvia officinalis, Satureja calamintha, Mentha pulegium and Marubium vulgare using ferric reducing power (FRAP) and radical scavenging method (DPPH). Preliminary phytochemical analysis shows that the major constituents of crude extracts (Hydromethanolic, hydroacetonic) are tannins, saponins, quinones, flavonoids, terpenoids and reducing compounds in the four plants. In quantitative analysis, variable polyphenols, flavonoids and condensed tannins content are recorded. The highest polyphenols content is that of the aqueous/methanol crude extract of Salvia officinalis (188.92 ± 1.19 mg GAE/ gE), followed by aqueous/acetone crude extract of Mentha pulegium (176.55 ± 2.49 mg GAE/gE). Flavonoids and condensed tannins content of crude extract showing a high content in aqueous/methanol extract of Mentha pulegium and Satureja calamintha (93.64 ± 0.26mg EQC/gE and 25.44 ± 0.71 mg EQC/gE), respectively. Scavenging activity of the free radical DPPH, revealed that the aqueous/methanol extract of Salvia officinalis shown a relatively high antioxidant activity (IC50 = 1.07 μg/ml) compared with ascorbic acid (IC50 = 0.91 μg/ml). FRAP method revealed that the extracts of Mentha pulegium showed the highest power to reduce iron (EC50 = 0.147 mg/ml), but lower than that of ascorbic acid (EC50 = 0.057 mg/mL).
{"title":"Phytochemical Screening, Total Phenolics Contents and in vitro Antioxidant Activity of Salvia officinalis, Satureja calamintha, Mentha pulegium and Marrubium vulgare","authors":"N. Belkacem, R. Azzi, R. Djaziri","doi":"10.3166/PHYTO-2021-0255","DOIUrl":"https://doi.org/10.3166/PHYTO-2021-0255","url":null,"abstract":"This study was designed to evaluate the antioxidant activity of phenolic compounds of for Lamiaceae: Salvia officinalis, Satureja calamintha, Mentha pulegium and Marubium vulgare using ferric reducing power (FRAP) and radical scavenging method (DPPH). Preliminary phytochemical analysis shows that the major constituents of crude extracts (Hydromethanolic, hydroacetonic) are tannins, saponins, quinones, flavonoids, terpenoids and reducing compounds in the four plants. In quantitative analysis, variable polyphenols, flavonoids and condensed tannins content are recorded. The highest polyphenols content is that of the aqueous/methanol crude extract of Salvia officinalis (188.92 ± 1.19 mg GAE/ gE), followed by aqueous/acetone crude extract of Mentha pulegium (176.55 ± 2.49 mg GAE/gE). Flavonoids and condensed tannins content of crude extract showing a high content in aqueous/methanol extract of Mentha pulegium and Satureja calamintha (93.64 ± 0.26mg EQC/gE and 25.44 ± 0.71 mg EQC/gE), respectively. Scavenging activity of the free radical DPPH, revealed that the aqueous/methanol extract of Salvia officinalis shown a relatively high antioxidant activity (IC50 = 1.07 μg/ml) compared with ascorbic acid (IC50 = 0.91 μg/ml). FRAP method revealed that the extracts of Mentha pulegium showed the highest power to reduce iron (EC50 = 0.147 mg/ml), but lower than that of ascorbic acid (EC50 = 0.057 mg/mL).","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89075895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethnobotanique ou ethnopharmacologie ?","authors":"P. Goetz","doi":"10.3166/PHYTO-2020-0243","DOIUrl":"https://doi.org/10.3166/PHYTO-2020-0243","url":null,"abstract":"","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"272 1","pages":"361-361"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74736844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rubus idaeus L. Huile de pépins de framboisier","authors":"P. Goetz","doi":"10.3166/phyto-2020-0239","DOIUrl":"https://doi.org/10.3166/phyto-2020-0239","url":null,"abstract":"","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"2015 1","pages":"353-356"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73559570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Les agrumes occupent une superficie importante de 65 000 ha en Algerie (2014), leurs fruits sont utilises dans l’alimentation humaine sous forme fraiche ou transformee, mais les feuilles sont communement utilisees en phytotherapie traditionnelle. Les bienfaits constates par la population nous ont incites a valoriser les feuilles de Citrus clementina recuperees apres la taille des arbres, par l’evaluation de l’activite antimicrobienne et la caracterisation chimique de leurs extraits flavonoides. L’etude quantitative en composes flavonoides montre un rendement de 11,2 % en flavonesflavonols, de 12,36 % en anthocyanes, de 17,87 % en heterosides et de 12,1 % en C-glycosides. L’etude par spectrophotometre UV-visible revele que l’extrait des feuilles renferme 2,48 ± 0,36 mg/g de flavones-flavonols, 3,33 ± 0,296 mg/g de C-glucosides, 0,34 ± 0,05 mg/g d’anthocyanes et 3,77 ± 0,20 mg/g d’heterosides. L’analyse par HPLC de l’extrait de feuilles de clementinier revele sa contenance en acide gallique (35,849 %), acide ascorbique (35,849 %), acide cafeique (area = 6,1803 %), acide benzoique (6,1125 %), catechine (23,4311 %) et rutine (6,0082 %). Ces extraits montrent une activite antimicrobienne variable a l’egard de tous les germes microbiens (Gram+, Gram– et levure) etudies. L’extrait flavones-flavonols montre une forte activite antimicrobienne a l’egard des souches Staphylococcus aureus , Staphylococcus epdermidis , Echerichia coli , Pseudomonas aeruginosa et Schacharomyces cervisai avec un diametre superieur a 20 mm et une concentration minimale d’inhibition (CMI) egale a 382, 150, 382 μg/ml et 0,380 mg/ml respectivement. Les autres extraits (anthocyanes et C-glycosides) ont un effet intermediaire, faible ou absent sur les micro-organismes testes. Le pouvoir bacteriostatique (CMI) de Staphylococcus aureus en milieu liquide est de 238 μg/ml, et le pouvoir bactericide (concentration minimale bactericide) est de 1,845 μg/ml. Cette methode de dilution est plus precise que celle de milieu gelose.
{"title":"Caractérisation chimique et évaluation de l’activité antimicrobienne des flavonoïdes extraits des feuilles de Citrus clementina de la région de la Mitidja (Algérie)","authors":"R. Belguendouz, H. Khelifa","doi":"10.3166/PHYTO-2018-0099","DOIUrl":"https://doi.org/10.3166/PHYTO-2018-0099","url":null,"abstract":"Les agrumes occupent une superficie importante de 65 000 ha en Algerie (2014), leurs fruits sont utilises dans l’alimentation humaine sous forme fraiche ou transformee, mais les feuilles sont communement utilisees en phytotherapie traditionnelle. Les bienfaits constates par la population nous ont incites a valoriser les feuilles de Citrus clementina recuperees apres la taille des arbres, par l’evaluation de l’activite antimicrobienne et la caracterisation chimique de leurs extraits flavonoides. L’etude quantitative en composes flavonoides montre un rendement de 11,2 % en flavonesflavonols, de 12,36 % en anthocyanes, de 17,87 % en heterosides et de 12,1 % en C-glycosides. L’etude par spectrophotometre UV-visible revele que l’extrait des feuilles renferme 2,48 ± 0,36 mg/g de flavones-flavonols, 3,33 ± 0,296 mg/g de C-glucosides, 0,34 ± 0,05 mg/g d’anthocyanes et 3,77 ± 0,20 mg/g d’heterosides. L’analyse par HPLC de l’extrait de feuilles de clementinier revele sa contenance en acide gallique (35,849 %), acide ascorbique (35,849 %), acide cafeique (area = 6,1803 %), acide benzoique (6,1125 %), catechine (23,4311 %) et rutine (6,0082 %). Ces extraits montrent une activite antimicrobienne variable a l’egard de tous les germes microbiens (Gram+, Gram– et levure) etudies. L’extrait flavones-flavonols montre une forte activite antimicrobienne a l’egard des souches Staphylococcus aureus , Staphylococcus epdermidis , Echerichia coli , Pseudomonas aeruginosa et Schacharomyces cervisai avec un diametre superieur a 20 mm et une concentration minimale d’inhibition (CMI) egale a 382, 150, 382 μg/ml et 0,380 mg/ml respectivement. Les autres extraits (anthocyanes et C-glycosides) ont un effet intermediaire, faible ou absent sur les micro-organismes testes. Le pouvoir bacteriostatique (CMI) de Staphylococcus aureus en milieu liquide est de 238 μg/ml, et le pouvoir bactericide (concentration minimale bactericide) est de 1,845 μg/ml. Cette methode de dilution est plus precise que celle de milieu gelose.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"12 1","pages":"291-300"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87190926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Afin de selectionner les plantes medicinales utilisees en medecine populaire pour traiter la Covid-19, une enquete en ligne a ete menee dans differentes regions du nord de l’Algerie Cinq cent personnes, dont 46 % atteintes de la Covid-19, appartenant a des groupes fermes sur Facebook, ont participe a cette etude Les questions portaient sur des donnees socio-economiques des participants et leurs perceptions de l’utilisation des plantes medicinales pour prevenir la Covid-19 Les donnees de cette enquete ont montre qu’une grande partie de la population algerienne utilise les plantes medicinales pour se proteger de la Covid-19 Les participants ont utilise 22 especes appartenant a 12 familles pour traiter la Covid-19 Les plantes medicinales cumulees aux medicaments antiviraux au debut du traitement ameliorent la therapie contre la Covid-19 La combinaison de la phytotherapie et de la medecine conventionnelle pourrait constituer une approche alternative au traitement de la Covid-19 a l’avenir In order to select the medicinal plants used in popular medicine to treat Covid-19, an online survey was conducted in different regions of northern Algeria Five hundred people, 46% of whom are affected by Covid-19 from closed groups on Facebook took part in this study The questions related to the socio-economic data of the participants and their perceptions of the use of medicinal plants to prevent Covid-19 The data of this survey showed that a large part of the Algerian population uses medicinal plants to protect them against Covid-19 The participants used 22 species belonging to 12 families to treat Covid-19 The use of herbal medicines in addition to antiviral drugs at the beginning of treatment improves therapy against Covid-19 The combination of phytotherapy and conventional medicine could be an alternative approach to treating Covid-19 in the future
为了选择用于治疗Covid-19的民间药物药用植物，在阿尔及利亚北部不同地区进行了一项在线调查，500人，其中46%是Covid-19患者，属于Facebook上的公司小组，都参与了这项研究的问题包括学员及其观念的社会经济数据的药用植物的使用,以防止Covid-19了这次调查,结果显示,绝大部分人口阿尔及利亚人民使用药用植物来保护自己不受Covid-19参加者使用旗下12户解决了现金22 Covid-19药用植物以及抗病毒药物的会计年度开始治疗ameliorent反Covid-19治疗相结合,和传统医学-不失为另一种方法治疗Covid-19 a未来In order to select the药用植物used In popular医学的“处理”Covid-19 an online, survey was In different)背上ship of northern angoisse)五分之一的人,46%,不要“受Covid-19影响are from Facebook groups人们走出prit part in this study The related to The失调问题data of The参与者and their perceptions of The use of药用植物to prevent Covid-19 The data of this survey·that a part of The阿尔及利亚人民广泛利用,药用植物to protect against The参与者Covid-19 used 22个品种(racial to进宫“处理家庭12 to The use of Covid-19 herbal in to担任了抗病毒药物加成的药在改善Covid-19治疗的初期，植物疗法和传统医学的结合可能是未来治疗Covid-19的替代方法
{"title":"Phytothérapie et Covid-19. Une étude fondée sur une enquête dans le nord de l’Algérie","authors":"F. Hamdani, N. Houari","doi":"10.3166/PHYTO-2020-0241","DOIUrl":"https://doi.org/10.3166/PHYTO-2020-0241","url":null,"abstract":"Afin de selectionner les plantes medicinales utilisees en medecine populaire pour traiter la Covid-19, une enquete en ligne a ete menee dans differentes regions du nord de l’Algerie Cinq cent personnes, dont 46 % atteintes de la Covid-19, appartenant a des groupes fermes sur Facebook, ont participe a cette etude Les questions portaient sur des donnees socio-economiques des participants et leurs perceptions de l’utilisation des plantes medicinales pour prevenir la Covid-19 Les donnees de cette enquete ont montre qu’une grande partie de la population algerienne utilise les plantes medicinales pour se proteger de la Covid-19 Les participants ont utilise 22 especes appartenant a 12 familles pour traiter la Covid-19 Les plantes medicinales cumulees aux medicaments antiviraux au debut du traitement ameliorent la therapie contre la Covid-19 La combinaison de la phytotherapie et de la medecine conventionnelle pourrait constituer une approche alternative au traitement de la Covid-19 a l’avenir In order to select the medicinal plants used in popular medicine to treat Covid-19, an online survey was conducted in different regions of northern Algeria Five hundred people, 46% of whom are affected by Covid-19 from closed groups on Facebook took part in this study The questions related to the socio-economic data of the participants and their perceptions of the use of medicinal plants to prevent Covid-19 The data of this survey showed that a large part of the Algerian population uses medicinal plants to protect them against Covid-19 The participants used 22 species belonging to 12 families to treat Covid-19 The use of herbal medicines in addition to antiviral drugs at the beginning of treatment improves therapy against Covid-19 The combination of phytotherapy and conventional medicine could be an alternative approach to treating Covid-19 in the future","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"1 1","pages":"248-254"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88664344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dose de plante et dose suffisante","authors":"P. Goetz","doi":"10.3166/phyto-2020-0242","DOIUrl":"https://doi.org/10.3166/phyto-2020-0242","url":null,"abstract":"","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"301 1","pages":"247-247"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75926556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L’objectif de cette etude est d’evaluer l’activite antibacterienne (in vitro) et antipyretique (in vivo) des extraits hydroalcooliques de trois organes (feuilles, rameaux et baies) de Juniperus phoenicea L. Le test de la sensibilite des souches bacteriennes (Escherichia coli ATCC25922, Pseudomonas aeruginosa ATCC27853, Staphylococcus aureus ATCC25923, Staphylococcus aureus subsp. aureus ATCC43300) a ete evalue vis-a-vis de nos extraits par la methode de diffusion en milieu gelose. La toxicite aigue a ete determinee par la methode de Lorke. L’hyperthermie chez les souris a ete induite par la levure de biere a 20 %. Les resultats montrent que les extraits des feuilles et des rameaux presentent un remarquable effet antibacterien sur les bacteries a Gram+. Le texte de toxicite aigue revele que les extraits de trois organes sont consideres comme des substances faiblement toxiques, l’administration intraperitoneale des extraits hydroalcooliques de trois organes, a differentes doses, reduit significativement l’hyperthermie. Ces resultats supportent, du moins partiellement, certaines indications therapeutiques traditionnelles de la plante.
{"title":"Évaluation de l’activité antibactérienne (in vitro) et l’activité antipyrétique (in vivo) de trois organes de Juniperus phoenicea L. de l’Ouest algérien","authors":"Y. Soltani, M. Bouzidi, F. Toumi, A. Benyamina","doi":"10.3166/phyto-2019-0203","DOIUrl":"https://doi.org/10.3166/phyto-2019-0203","url":null,"abstract":"L’objectif de cette etude est d’evaluer l’activite antibacterienne (in vitro) et antipyretique (in vivo) des extraits hydroalcooliques de trois organes (feuilles, rameaux et baies) de Juniperus phoenicea L. Le test de la sensibilite des souches bacteriennes (Escherichia coli ATCC25922, Pseudomonas aeruginosa ATCC27853, Staphylococcus aureus ATCC25923, Staphylococcus aureus subsp. aureus ATCC43300) a ete evalue vis-a-vis de nos extraits par la methode de diffusion en milieu gelose. La toxicite aigue a ete determinee par la methode de Lorke. L’hyperthermie chez les souris a ete induite par la levure de biere a 20 %. Les resultats montrent que les extraits des feuilles et des rameaux presentent un remarquable effet antibacterien sur les bacteries a Gram+. Le texte de toxicite aigue revele que les extraits de trois organes sont consideres comme des substances faiblement toxiques, l’administration intraperitoneale des extraits hydroalcooliques de trois organes, a differentes doses, reduit significativement l’hyperthermie. Ces resultats supportent, du moins partiellement, certaines indications therapeutiques traditionnelles de la plante.","PeriodicalId":21877,"journal":{"name":"Sozial- und Praventivmedizin","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85850876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：