{"title":"Biomarkers for diagnosis of sepsis in patients with systemic inflammatory response syndrome: a systematic review and meta-analysis","authors":"Yong Liu, Jun-huan Hou, Qing Li, Kui-Jun Chen, Shu-Nan Wang, Jian-Min Wang","doi":"10.1186/s40064-016-3591-5","DOIUrl":"https://doi.org/10.1186/s40064-016-3591-5","url":null,"abstract":"","PeriodicalId":21923,"journal":{"name":"SpringerPlus","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40064-016-3591-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65819483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-09DOI: 10.1186/s40064-016-3748-2
A. Q. Mohamad, I. Khan, Z. Ismail, S. Shafie
{"title":"Exact solutions for unsteady free convection flow over an oscillating plate due to non-coaxial rotation","authors":"A. Q. Mohamad, I. Khan, Z. Ismail, S. Shafie","doi":"10.1186/s40064-016-3748-2","DOIUrl":"https://doi.org/10.1186/s40064-016-3748-2","url":null,"abstract":"","PeriodicalId":21923,"journal":{"name":"SpringerPlus","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40064-016-3748-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65821645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-09DOI: 10.1186/s40064-016-3757-1
Samira Alinejad, K. Ghaemi, M. Abdollahi, O. Mehrpour
{"title":"Nephrotoxicity of methadone: a systematic review","authors":"Samira Alinejad, K. Ghaemi, M. Abdollahi, O. Mehrpour","doi":"10.1186/s40064-016-3757-1","DOIUrl":"https://doi.org/10.1186/s40064-016-3757-1","url":null,"abstract":"","PeriodicalId":21923,"journal":{"name":"SpringerPlus","volume":"106 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40064-016-3757-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65821884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-09DOI: 10.1186/s40064-016-3768-y
E. Ranganai, Sihle Kubheka
{"title":"Long memory mean and volatility models of platinum and palladium price return series under heavy tailed distributions","authors":"E. Ranganai, Sihle Kubheka","doi":"10.1186/s40064-016-3768-y","DOIUrl":"https://doi.org/10.1186/s40064-016-3768-y","url":null,"abstract":"","PeriodicalId":21923,"journal":{"name":"SpringerPlus","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40064-016-3768-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65822264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Rice breeding program needs to focus on development of nutrient dense rice for value addition and helping in reducing malnutrition. Mineral and vitamin deficiency related problems are common in the majority of the population and more specific to developing countries as their staple food is rice.
Results: Genes and QTLs are recently known for the nutritional quality of rice. By comprehensive literature survey and public domain database, we provided a critical review on nutritional aspects like grain protein and amino acid content, vitamins and minerals, glycemic index value, phenolic and flavonoid compounds, phytic acid, zinc and iron content along with QTLs linked to these traits. In addition, achievements through transgenic and advanced genomic approaches have been discussed. The information available on genes and/or QTLs involved in enhancement of micronutrient element and amino acids are summarized with graphical representation.
Conclusion: Compatible QTLs/genes may be combined together to design a desirable genotype with superior in multiple grain quality traits. The comprehensive review will be helpful to develop nutrient dense rice cultivars by integrating molecular markers and transgenic assisted breeding approaches with classical breeding.
{"title":"Rice grain nutritional traits and their enhancement using relevant genes and QTLs through advanced approaches.","authors":"Anumalla Mahender, Annamalai Anandan, Sharat Kumar Pradhan, Elssa Pandit","doi":"10.1186/s40064-016-3744-6","DOIUrl":"10.1186/s40064-016-3744-6","url":null,"abstract":"<p><strong>Background: </strong>Rice breeding program needs to focus on development of nutrient dense rice for value addition and helping in reducing malnutrition. Mineral and vitamin deficiency related problems are common in the majority of the population and more specific to developing countries as their staple food is rice.</p><p><strong>Results: </strong>Genes and QTLs are recently known for the nutritional quality of rice. By comprehensive literature survey and public domain database, we provided a critical review on nutritional aspects like grain protein and amino acid content, vitamins and minerals, glycemic index value, phenolic and flavonoid compounds, phytic acid, zinc and iron content along with QTLs linked to these traits. In addition, achievements through transgenic and advanced genomic approaches have been discussed. The information available on genes and/or QTLs involved in enhancement of micronutrient element and amino acids are summarized with graphical representation.</p><p><strong>Conclusion: </strong>Compatible QTLs/genes may be combined together to design a desirable genotype with superior in multiple grain quality traits. The comprehensive review will be helpful to develop nutrient dense rice cultivars by integrating molecular markers and transgenic assisted breeding approaches with classical breeding.</p>","PeriodicalId":21923,"journal":{"name":"SpringerPlus","volume":"5 1","pages":"2086"},"PeriodicalIF":0.0,"publicationDate":"2016-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65821559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-08DOI: 10.1186/s40064-016-3759-z
Yuanjun Ma, Y. Miao, Z. Peng, J. Sandgren, T. de Ståhl, M. Huss, L. Lennartsson, Yanling Liu, M. Nistér, S. Nilsson, Chunde Li
{"title":"Erratum to: Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells","authors":"Yuanjun Ma, Y. Miao, Z. Peng, J. Sandgren, T. de Ståhl, M. Huss, L. Lennartsson, Yanling Liu, M. Nistér, S. Nilsson, Chunde Li","doi":"10.1186/s40064-016-3759-z","DOIUrl":"https://doi.org/10.1186/s40064-016-3759-z","url":null,"abstract":"","PeriodicalId":21923,"journal":{"name":"SpringerPlus","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40064-016-3759-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65821936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Chemotherapy-induced nausea and vomiting (CINV) is a major adverse toxicity of cancer chemotherapy. Recommended treatments for prevention of CINV vary among published guidelines, and optimal care for CINV caused by moderately emetogenic chemotherapy has not been established. This study assessed the efficacy and safety of triple antiemetic therapy comprising palonosetron, dexamethasone and aprepitant for carboplatin-based chemotherapy. Chemotherapy-naïve patients with lung cancer scheduled for a first course of a carboplatin-containing regimen formed the study cohort. Patients were pretreated with antiemetic therapy comprising palonosetron (0.75 mg, i.v.) and dexamethasone (9.9 mg, i.v.) on day 1, and aprepitant (125 mg, p.o.) on day 1 followed by 80 mg on days 2 and 3. Primary endpoint was the proportion of patients who did not experience vomiting and did not require rescue medication [complete response (CR)] in the acute phase (0-24 h), late phase (24-168 h) and overall. Secondary endpoint was the proportion of patients who experienced no vomiting episodes and no more than mild nausea without the need for rescue medication [complete control (CC)].
Results: Prevalence of a CR during the acute phase, delayed phase, and overall was 100, 91.9 and 91.9%, whereas that of CC was 100, 84.4 and 84.4%, respectively. The most common adverse event was mild constipation; severe adverse events related to antiemetic treatment were not observed.
Conclusion: Triple antiemetic therapy comprising palonosetron, dexamethasone and aprepitant shows excellent effects in the prevention of CINV in patients receiving a carboplatin-containing regimen.
{"title":"Efficacy of triple antiemetic therapy (palonosetron, dexamethasone, aprepitant) for chemotherapy-induced nausea and vomiting in patients receiving carboplatin-based, moderately emetogenic chemotherapy.","authors":"Toshimichi Miya, Kunihiko Kobayashi, Mitsunori Hino, Masahiro Ando, Susumu Takeuchi, Masahiro Seike, Kaoru Kubota, Akihiko Gemma","doi":"10.1186/s40064-016-3769-x","DOIUrl":"10.1186/s40064-016-3769-x","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy-induced nausea and vomiting (CINV) is a major adverse toxicity of cancer chemotherapy. Recommended treatments for prevention of CINV vary among published guidelines, and optimal care for CINV caused by moderately emetogenic chemotherapy has not been established. This study assessed the efficacy and safety of triple antiemetic therapy comprising palonosetron, dexamethasone and aprepitant for carboplatin-based chemotherapy. Chemotherapy-naïve patients with lung cancer scheduled for a first course of a carboplatin-containing regimen formed the study cohort. Patients were pretreated with antiemetic therapy comprising palonosetron (0.75 mg, i.v.) and dexamethasone (9.9 mg, i.v.) on day 1, and aprepitant (125 mg, p.o.) on day 1 followed by 80 mg on days 2 and 3. Primary endpoint was the proportion of patients who did not experience vomiting and did not require rescue medication [complete response (CR)] in the acute phase (0-24 h), late phase (24-168 h) and overall. Secondary endpoint was the proportion of patients who experienced no vomiting episodes and no more than mild nausea without the need for rescue medication [complete control (CC)].</p><p><strong>Results: </strong>Prevalence of a CR during the acute phase, delayed phase, and overall was 100, 91.9 and 91.9%, whereas that of CC was 100, 84.4 and 84.4%, respectively. The most common adverse event was mild constipation; severe adverse events related to antiemetic treatment were not observed.</p><p><strong>Conclusion: </strong>Triple antiemetic therapy comprising palonosetron, dexamethasone and aprepitant shows excellent effects in the prevention of CINV in patients receiving a carboplatin-containing regimen.</p>","PeriodicalId":21923,"journal":{"name":"SpringerPlus","volume":"5 1","pages":"2080"},"PeriodicalIF":0.0,"publicationDate":"2016-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65822274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-07DOI: 10.1186/s40064-016-3776-y
N. Young, M. Wabano, K. Usuba, Debbie Mishibinijima, Diane Jacko, Tricia A. Burke
{"title":"Reliability of the Aboriginal Children’s Health and Well-Being Measure (ACHWM)","authors":"N. Young, M. Wabano, K. Usuba, Debbie Mishibinijima, Diane Jacko, Tricia A. Burke","doi":"10.1186/s40064-016-3776-y","DOIUrl":"https://doi.org/10.1186/s40064-016-3776-y","url":null,"abstract":"","PeriodicalId":21923,"journal":{"name":"SpringerPlus","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40064-016-3776-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65822439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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