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The influencing factors for tracheostomy decannulation after traumatic cervical spinal cord injury: a retrospective study. 外伤性颈脊髓损伤后气管造口拔管的影响因素:一项回顾性研究。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-11-19 DOI: 10.1038/s41393-024-01048-8
Yongqi Xie, Weichao Zhao, Run Peng, Liang Zhang, Yunxiao Jia, Mingliang Yang, Lianjun Guo

Study design: Retrospective study.

Objective: To investigate the outcomes and influencing factors of tracheostomy decannulation (TD) in persons with traumatic cervical spinal cord injury (SCI).

Setting: China Rehabilitation Research Center (CRRC) in Beijing, China.

Methods: From January 2017 to December 2021, 365 persons with traumatic cervical SCI were admitted to the China Rehabilitation Research Center. During hospitalization, tracheostomy patients were enrolled and divided into the TD group and non-TD group. Demographic and clinical data, as well as functional assessments, were collected and recorded for all persons. The factors influencing TD were analyzed using both univariate and multivariate logistic regression.

Results: A total of 78 persons with traumatic cervical SCI from CRRC were enrolled in this study. Of these, 48 persons (61.5%) underwent successful decannulation, with a median time of 93.5 days (IQR: 62.0-143.8 days). Multivariate logistic regression revealed that AIS A (P = 0.021, OR: 5.378, 95% CI, 1.287-22.474) and Charlson comorbidity index (CCI) (P = 0.003, OR: 1.836, 95% CI, 1.230-2.740) were significant risk factors of reduced success in TD. PEF in the TD group was 145.44 ± 50.56 L/min. Middle-aged and young persons with traumatic cervical SCI at C3 to C5 neurological level did not satisfy the criterion of PEF (over 160 L/min), but they can still attempt tracheostomy decannulation.

Conclusion: AIS A and a high CCI will reduce the success rate of tracheostomy decannulation in persons suffering from traumatic cervical SCI.

研究设计回顾性研究:调查外伤性颈脊髓损伤(SCI)患者气管切开术(TD)的结果和影响因素:中国康复研究中心(CRRC),北京:2017年1月至2021年12月,中国康复研究中心收治了365名外伤性颈椎脊髓损伤患者。住院期间,气管切开患者被纳入其中,并分为TD组和非TD组。收集并记录所有患者的人口统计学和临床数据以及功能评估。采用单变量和多变量逻辑回归分析了影响TD的因素:本研究共纳入了 78 名来自中国康复研究中心的创伤性颈椎 SCI 患者。其中,48 人(61.5%)成功进行了解禁,中位时间为 93.5 天(IQR:62.0-143.8 天)。多变量逻辑回归显示,AIS A(P = 0.021,OR:5.378,95% CI,1.287-22.474)和Charlson合并症指数(CCI)(P = 0.003,OR:1.836,95% CI,1.230-2.740)是导致TD成功率降低的重要风险因素。TD 组的 PEF 为 145.44 ± 50.56 L/min。患有外伤性颈椎 SCI(C3 至 C5 神经水平)的中年人和年轻人不符合 PEF(160 升/分钟以上)的标准,但他们仍可尝试气管切开术:结论:AIS A 和高 CCI 会降低外伤性颈椎 SCI 患者气管切开术的成功率。
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引用次数: 0
"What should a rehabilitation hospital be like?" Priorities and expectations of people with spinal cord injury in Türkiye. "康复医院应该是什么样的?土耳其脊髓损伤患者的优先事项和期望。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-11-15 DOI: 10.1038/s41393-024-01049-7
Mucahit Atasoy, Eser Kalaoglu, Omer Faruk Bucak, Evrim Coskun

Study design: Survey study OBJECTIVES: To understand the priorities and expectations of individuals with disabilities caused by spinal cord injuries(SCI) who require long-term inpatient rehabilitation at a rehabilitation hospital.

Setting: Başakşehir Çam and Sakura City Hospital, İstanbul, Türkiye METHODS: This cross-sectional clinical study included individuals over the age of 18 with SCI who had previously been hospitalized in a rehabilitation hospital. The 18-question survey, titled "What should a rehabilitation hospital be like according to persons with spinal cord injuries?" was administered to individuals hospitalized in the inpatient service of Çam Sakura City Hospital. It was also disseminated to people with SCI through social media. The participants' demographic data was recorded.

Results: The survey was completed by 120 participants, comprising 70 males and 50 females. The mean age was 37.47 ± 11.63 years. The time since the SCI was less than one year for 20 individuals and more than one year for 100 individuals. The results showed that robotic rehabilitation and psychological support were the most requested rehabilitation domains, while interest in sexual rehabilitation was less than that in other rehabilitation domains. Furthermore, in the correlation analysis, elderly participants indicated that there should be more specialized services and outpatient clinics exclusive to the SCI.

Conclusions: The study revealed a striking trend - participants expressed a strong desire for SCI-specific rehabilitation units and robotic rehabilitation. Additionally, the significance and necessity of sexual rehabilitation should be conveyed to people with SCI.

研究设计:调查研究了解需要在康复医院接受长期住院康复治疗的脊髓损伤(SCI)致残者的优先事项和期望:方法:这项横断面临床研究的对象包括曾在康复医院住院治疗的 18 岁以上 SCI 患者。在Çam Sakura市医院住院治疗的患者接受了题为 "脊髓损伤患者眼中的康复医院应该是什么样的?"的18个问题的调查。该问卷还通过社交媒体向脊髓损伤患者进行了传播。对参与者的人口统计学数据进行了记录:120 名参与者完成了调查,其中男性 70 人,女性 50 人。平均年龄为 37.47±11.63 岁。20 人的 SCI 时间不足一年,100 人的 SCI 时间超过一年。结果显示,机器人康复和心理支持是老年人要求最多的康复领域,而对性康复的兴趣低于其他康复领域。此外,在相关性分析中,老年参与者表示应提供更多专为 SCI 而设的专业服务和门诊:这项研究揭示了一个显著的趋势--参与者表达了对 SCI 专用康复单元和机器人康复的强烈愿望。此外,应向 SCI 患者宣传性康复的意义和必要性。
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引用次数: 0
The effect of abdominal functional electrical stimulation on blood pressure in people with high level spinal cord injury. 腹部功能性电刺激对高位脊髓损伤患者血压的影响。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-11-01 DOI: 10.1038/s41393-024-01046-w
Teodora Bojanic, Euan J McCaughey, Harrison T Finn, Peter Humburg, Rachel A McBain, Bonsan B Lee, Simon C Gandevia, Claire L Boswell-Ruys, Jane E Butler

Study design: Single centre training study.

Objectives: To investigate, in a group of people with spinal cord injury (SCI), the effect of transcutaneous functional electrical stimulation of the abdominal muscles (abdominal FES) during cough training on blood pressure (BP), and how it is affected by injury characteristics and alters over time.

Setting: Laboratory and community.

Methods: Sixteen participants with SCI (C4-T5) underwent 25 of abdominal FES cough training (5 sets of 10 stimulated coughs) over 6 weeks as part of a previously published study on the effect of abdominal FES training on cough. Systolic BP (SBP), diastolic BP (DBP) and calculated mean arterial pressure (MAP) were measured at the completion of each set.

Results: Abdominal FES coughing resulted in an average ~30% acute increase in BP from initial resting BP across all sessions in almost all participants (p < 0.001). However, the increase in BP during abdominal FES coughs from rest reduced over the 25 sessions of training by ~35% for SBP, MAP and DBP (p = 0.024, p = 0.013 and p = 0.042, respectively). There was no meaningful change in resting BP over time (p = 0.935, p = 0.705 and p = 0.988, respectively). Overall, increases in BP during abdominal FES coughs were greatest for those with chronic injuries and cervical injuries.

Conclusions: Transcutaneous abdominal FES during cough training acutely increases BP. However, the magnitude of the increase is reduced after 25 sessions of training. Abdominal FES may offer a solution to combat orthostatic hypotension, but its effectiveness may diminish over time.

研究设计单中心训练研究:调查一组脊髓损伤(SCI)患者在咳嗽训练中腹部肌肉经皮功能性电刺激(腹部FES)对血压(BP)的影响,以及血压受损伤特征的影响和随时间的变化:环境:实验室和社区:方法:16 名患有 SCI(C4-T5)的参与者在 6 周内接受了 25 次腹部 FES 咳嗽训练(5 组 10 次刺激性咳嗽),这是之前发表的腹部 FES 训练对咳嗽影响研究的一部分。每组训练结束后测量收缩压(SBP)、舒张压(DBP)和计算出的平均动脉压(MAP):结果:腹部 FES 咳嗽使几乎所有参与者的血压从最初的静息血压平均急剧升高约 30%(p 结论:腹部 FES 咳嗽使血压从最初的静息血压平均急剧升高约 30%(p):咳嗽训练中经皮腹部外展电刺激可使血压急剧升高。然而,训练 25 次后,血压升高的幅度会减小。腹部外展电刺激可能是对抗正性低血压的一种解决方案,但其效果可能会随着时间的推移而减弱。
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引用次数: 0
Mortality and causes of death of traumatic spinal cord injury in Finland. 芬兰外伤性脊髓损伤的死亡率和死亡原因。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-30 DOI: 10.1038/s41393-024-01047-9
Elina Johansson, Eerika Koskinen, Mika Helminen, Aki Vainionpää, Teemu M Luoto

Study design: Prospective cohort study.

Objectives: To study the mortality rates of TSCI patients compared to matched controls and to examine possible TSCI-related mortality risk factors and causes of death.

Setting: Oulu and Tampere University Hospital, Finland.

Methods: All consecutive patients with a new TSCI were included in a prospective study (n = 344, 2012-16). All patients were followed until death or the end of 2019. Patients were compared to a control group formed by randomly choosing gender, age, municipality, and calendar time-matched controls (5 controls/TSCI patient). Standardized mortality ratios (SMR) were calculated using general population mortality rates. Mortality information was extracted from the Statistics of Finland (Helsinki, Finland).

Results: TSCI patients had an increased mortality (SMR = 2.9) compared with the Finnish population. During the observation period, 26% of TSCI patients and 12% of the matched controls died. Of the TSCI patient deaths, 51% occurred within the first two years postinjury. Increased age, severity of TSCI (as per International SCI Core Data Set) and fall were related to mortality (p < 0.05). The two most common etiologies of death were: circulatory (30%), and pulmonary diseases (28%). Pneumonia was the single most frequent disease leading to death among TSCI patients.

Conclusions: During the first years after injury, the mortality of the patients with TSCI is double compared to the controls. Most deaths occur within two years postinjury. Elderly patients with more severe fall-related injury have the highest mortality risk. Circulatory diseases and pulmonary diseases, especially pneumonia, are the foremost causes of death after TSCI.

研究设计前瞻性队列研究:研究TSCI患者与匹配对照组相比的死亡率,并探讨可能与TSCI相关的死亡风险因素和死亡原因:芬兰奥卢和坦佩雷大学医院:一项前瞻性研究纳入了所有新发 TSCI 的连续患者(n = 344,2012-16 年)。所有患者均接受随访,直至死亡或2019年底。通过随机选择性别、年龄、城市和日历时间匹配的对照组(5 名对照组/TSCI 患者),将患者与对照组进行比较。标准化死亡率(SMR)采用一般人口死亡率计算。死亡率信息来自芬兰统计局(芬兰赫尔辛基):结果:与芬兰人口相比,TSCI 患者的死亡率更高(SMR = 2.9)。在观察期间,26%的TSCI患者死亡,12%的匹配对照组患者死亡。在TSCI患者的死亡病例中,51%发生在受伤后的头两年内。年龄、TSCI 严重程度(根据国际 SCI 核心数据集)和跌倒的增加与死亡率有关(P 结论):在受伤后的最初几年,TSCI 患者的死亡率是对照组的两倍。大多数死亡发生在伤后两年内。摔伤较严重的老年患者死亡风险最高。循环系统疾病和肺部疾病,尤其是肺炎,是创伤性脑损伤后死亡的首要原因。
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引用次数: 0
Correspondence to "Walking improvement in chronic incomplete spinal cord injury with exoskeleton robotic training (WISE): a randomized controlled trial". 通讯:"通过外骨骼机器人训练(WISE)改善慢性不完全脊髓损伤患者的行走能力:随机对照试验"。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-28 DOI: 10.1038/s41393-024-01043-z
Meriç Selim Şipal
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引用次数: 0
Response: Use of the WISCI-II score in assessing outcome of intensive robot-assisted gait training in spinal cord injury. 回应:使用 WISCI-II 评分评估脊髓损伤患者强化机器人辅助步态训练的效果。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-28 DOI: 10.1038/s41393-024-01044-y
D J Edwards, A Jayaraman
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引用次数: 0
Learning to direct one's care: barriers and facilitators reported by people with tetraplegia. 学习指导自己的护理:四肢瘫痪者报告的障碍和促进因素。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-26 DOI: 10.1038/s41393-024-01045-x
Jeanne M Zanca, Carol M Gibson-Gill, Joyce Williams, Tomicka McMillion, John T Morris, Marcel P Dijkers

Study design: Qualitative analysis of focus group data.

Objective: Identifying barriers to and facilitators of learning to direct one's own care as a person with tetraplegia due to spinal cord injury (SCI).

Setting: Community, in New Jersey and Georgia, USA.

Methods: Three focus groups of veterans and civilians with SCI, involving 26 people with chronic (≥1 year) tetraplegia due to SCI who provided direction to caregivers on a daily basis. Content analysis was used to identify barriers and facilitators.

Results: Challenges to learning to direct one's care included: (1) lack of acceptance of lasting effects of SCI; (2) not yet understanding one's body post-SCI; (3) embarrassment; (4) being overwhelmed with information; (5) differences between the inpatient rehabilitation setting and the "real world"; (6) lack of capable and willing assistants; and (7) hesitance to criticize caregivers. Factors that helped participants become successful directors of care included: (1) experience living with SCI; (2) being observant; (3) communicating effectively; (4) developing confidence to advocate for one's own needs; (5) learning when to "let go" and when to speak up; and (6) learning from peers.

Conclusions: Direction of care is a complex skill that is developed over time, and requires awareness of one's needs and preferences, self-confidence, and strong communication skills. Rehabilitation clinicians' efforts to prepare people with SCI to direct their own care effectively should cultivate awareness of one's body, identify strategies for communicating successfully with caregivers, and provide opportunities for practice of care direction skills and discussion with experienced peers.

研究设计:对焦点小组数据进行定性分析:确定因脊髓损伤(SCI)导致四肢瘫痪的患者在学习指导自身护理过程中遇到的障碍和促进因素:环境:美国新泽西州和佐治亚州的社区:方法:由患有 SCI 的退伍军人和平民组成三个焦点小组,共有 26 名因 SCI 长期(≥1 年)四肢瘫痪的患者参加,他们每天为护理人员提供指导。内容分析法用于确定障碍和促进因素:结果:学习指导个人护理所面临的挑战包括(结果:学习指导护理的挑战包括:(1)不接受 SCI 的持久影响;(2)还不了解自己 SCI 后的身体;(3)尴尬;(4)被信息淹没;(5)住院康复环境与 "真实世界 "之间的差异;(6)缺乏有能力且愿意提供帮助的助手;以及(7)对批评护理人员犹豫不决。帮助参与者成为成功的护理主任的因素包括(1) SCI 患者的生活经验;(2) 善于观察;(3) 有效沟通;(4) 树立为自己的需求辩护的信心;(5) 学会何时 "放手",何时大声说话;(6) 向同伴学习:护理指导是一项复杂的技能,需要经过长期的发展,并需要对自身需求和偏好的认识、自信心和强大的沟通能力。康复临床医生在培养 SCI 患者有效指导自己的护理时,应培养他们对自己身体的认识,确定与护理人员成功沟通的策略,并提供机会练习护理指导技能和与有经验的同伴进行讨论。
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引用次数: 0
Is neck pain a marker for something serious? Like myelopathy. 颈部疼痛是严重疾病的标志吗?比如脊髓病变。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-14 DOI: 10.1038/s41393-024-01041-1
Alisha W Sial, Stone Sima, Rajpal Narulla, Nashwa Najib, Mark Davies, Ashish D Diwan

Degenerative Cervical Myelopathy (DCM) is a chronic progressive condition of the cervical spine that leads to compression of the spinal cord. It is the most common cause of spinal cord dysfunction in adults, and it occurs due to age-related changes or genetically associated pathologies. DCM is a clinical and radiological diagnosis and presents with a spectrum of symptoms ranging from neck pain and stiffness to paralysis. While neck pain is prevalent amongst patients attending specialist clinics, its predictive value for DCM is limited. This paper focuses on elucidating the relationship between DCM and chronic neck pain, and we discuss the underlying aetiology and broader neurological implications in the context of the literature. The progression of DCM can be slow and insidious with symptoms worsening gradually over time. Neck pain should not be discounted in the evaluation of DCM.

颈椎退行性脊髓病(DCM)是一种慢性进行性颈椎病,会导致脊髓受压。它是导致成人脊髓功能障碍的最常见原因,其发生是由于与年龄相关的变化或与遗传相关的病变。DCM 是一种临床和放射学诊断,表现为从颈部疼痛、僵硬到瘫痪的一系列症状。虽然颈部疼痛在专科门诊就诊的患者中很普遍,但其对 DCM 的预测价值却很有限。本文重点阐明了 DCM 与慢性颈痛之间的关系,并结合文献讨论了其基本病因和更广泛的神经学影响。DCM 的进展缓慢而隐匿,症状会随着时间的推移逐渐恶化。在评估 DCM 时不应忽视颈痛。
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引用次数: 0
Does the presence or absence of preoperative lower extremity neurologic symptoms influence postoperative clinical outcome in patients with cervical intradural extramedullary tumors?: a single-center retrospective comparative study. 颈椎硬膜外肿瘤患者术前有无下肢神经症状会影响术后临床预后吗:一项单中心回顾性比较研究。
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-09 DOI: 10.1038/s41393-024-01042-0
Toshiki Okubo, Narihito Nagoshi, Takahito Iga, Kazuki Takeda, Masahiro Ozaki, Satoshi Suzuki, Morio Matsumoto, Masaya Nakamura, Kota Watanabe

Study design: Retrospective comparative study OBJECTIVES: To investigate whether the presence or absence of preoperative lower extremities neurological symptoms (LENS) influences clinical outcomes following tumor resection in patients with cervical intradural extramedullary (IDEM) tumors.

Setting: The single institution in Japan.

Methods: Ninety-two patients with cervical IDEM tumors requiring surgical resection were included. Based on the degree of preoperative LENS assessed using the modified McCormick scale (MMCS), patients were categorized into LENS (-) and (+) groups. Demographic and surgical characteristics were compared between both groups.

Results: There were no significant differences observed in sex, tumor location, tumor size, surgical time, estimated blood loss, approach for tumorectomy, or tumor histopathology between the two groups. Additionally, the overall surgical outcomes were favorable for both groups. At the final follow-up, 91.1% of the patients in the LENS (+) group were able to walk without support. Improvement in LENS was observed after surgery in most patients with preoperative MMCS II-IV, but it persisted in approximately 40% of patients with preoperative MMCS V. In the LENS (+) group, there were no significant differences in demographic or surgical data between the patients with MMCS I and II-III at the final follow-up.

Conclusions: Regardless of the presence or absence of preoperative LENS, clinical improvement was observed after tumor resection in most patients with cervical IDEM tumors. These findings suggest that neurological status is likely to improve sufficiently if tumor resection is performed before preoperative LENS deteriorates to an extremely severe stage as MMCS V.

研究设计:回顾性比较研究 目的研究颈椎硬膜外肿瘤(IDEM)患者术前是否出现下肢神经症状(LENS)是否会影响肿瘤切除术后的临床预后:方法方法:纳入92例需要手术切除的颈椎IDEM肿瘤患者。根据使用改良麦考密克量表(MMCS)评估的术前LENS程度,将患者分为LENS(-)组和(+)组。对两组患者的人口统计学特征和手术特征进行比较:结果:两组患者在性别、肿瘤位置、肿瘤大小、手术时间、估计失血量、肿瘤切除方式或肿瘤组织病理学方面均无明显差异。此外,两组患者的总体手术效果良好。在最后的随访中,LENS(+)组有91.1%的患者能够在没有支撑的情况下行走。在 LENS(+)组中,MMCS I 和 II-III 患者的人口统计学和手术数据在最终随访时没有显著差异:结论:无论术前是否存在LENS,大多数颈部IDEM肿瘤患者在肿瘤切除后临床症状都有所改善。这些研究结果表明,如果在术前 LENS 恶化到 MMCS V 的极其严重阶段之前进行肿瘤切除,神经状况很可能会得到充分改善。
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引用次数: 0
Disability trajectories individuals with spinal cord injury in mainland China: do psychosocial resources and diseases factors predict trajectories? 中国大陆脊髓损伤患者的残疾轨迹:社会心理资源和疾病因素能否预测残疾轨迹?
IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-08 DOI: 10.1038/s41393-024-01040-2
Hui Huang, Mengmeng Chen, Peipei Ding, Xiaoxiao Xia, Qing Dai, Linsheng Feng, Li Xu, Junmei Shu, Lunlan Li

Study design: Observational cohort study.

Objective: To identify classes of disability trajectories from 1 month post-injury (acute hospital) to 6 months post-injury (individuals with SCI individuals who stay in rehabilitation setting or back in the community), and to investigate whether psychosocial resources and disease factors can predict disability trajectory.

Setting: Spinal surgery in three Class III hospitals. Hospitals in China are divided into three classes (Class I, II and III).

Methods: All the participants were submitted to WHO Disability Assessment Schedule (WHO-DAS 2.0) at three times; and personal data anamnesis, level of hope, level of PTSD, level of social support were recorded at first time. All the data collected by the master's students who participated in this study.

Results: Two disability trajectories were identified using the latent class growth model: the continuous high disability group (N = 196, 93.3%) and the low starting point stabilization group (N = 14, 6.7%). Complete injury(ASIA-A) with SCI and more depression in the stable condition after SCI surgery were more likely to be classified as having higher disability than those with a lower disability trajectory. Occupation, annual family income, hope, social support, and Post-traumatic Stress Disorder (PTSD) cannot predict individuals belonging to trajectory classes.

Conclusion: These findings emphasize the importance of ASIA and depression in the early recovery stage after SCI and support the opinion that strengthening psychological nursing and rehabilitation management at an early stage after SCI will benefit individuals with a lower disability trajectory.

研究设计观察性队列研究:确定从伤后1个月(急性期住院)到伤后6个月(在康复机构住院或重返社区的SCI患者)的残疾轨迹等级,并研究社会心理资源和疾病因素是否能预测残疾轨迹:环境:三家三级医院的脊柱外科。中国的医院分为三级(一级、二级和三级):方法:对所有受试者进行3次WHO残疾评估表(WHO-DAS 2.0),并在第一次评估表中记录受试者的个人资料、希望程度、创伤后应激障碍程度、社会支持程度。所有数据均由参与本研究的硕士研究生收集:利用潜类增长模型确定了两种残疾轨迹:连续高残疾组(196 人,占 93.3%)和低起点稳定组(14 人,占 6.7%)。完全损伤(ASIA-A)的 SCI 患者和 SCI 术后稳定状态下的抑郁症患者比残疾轨迹较低的患者更有可能被归类为残疾程度较高的患者。职业、家庭年收入、希望、社会支持和创伤后应激障碍(PTSD)无法预测属于不同轨迹等级的个体:这些发现强调了ASIA和抑郁症在SCI术后早期恢复阶段的重要性,并支持在SCI术后早期加强心理护理和康复管理将使残疾轨迹较低的个体受益的观点。
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引用次数: 0
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