I M Korochkin, I A Verbitskaia, I N Okuneva, V E Krupnik, O Iu Polevaia
The important role played by prostaglandins in the pathogenesis of coronary disease and essential hypertension is well known. The authors have attempted to reveal a relationship between blood levels of natural autoantibodies to PGF2 alpha and PGE2 and specific features of coronary disease and essential hypertension course and complications. A total of 87 subjects were examined, 23 of these--normal controls, 25 patients with myocardial infarction, 22 with angina pectoris, and 17 with essential hypertension. Solid-phase enzyme immunoassay was employed to detect anti-PGF2 alpha and anti-PGE2 antibodies. These antibodies were found in normal subjects, coronary patients and hypertensives. Blood levels of these antibodies correlated with some complications of coronary disease and essential hypertension. These results permit a hypothesis that the pathogenetic physiologic role of the detected natural antibodies to prostaglandins consists in their defense homeostatic function.
{"title":"[Natural anti-PGF2alpha and anti-PGE2 antibodies in ischemic heart disease and hypertension].","authors":"I M Korochkin, I A Verbitskaia, I N Okuneva, V E Krupnik, O Iu Polevaia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The important role played by prostaglandins in the pathogenesis of coronary disease and essential hypertension is well known. The authors have attempted to reveal a relationship between blood levels of natural autoantibodies to PGF2 alpha and PGE2 and specific features of coronary disease and essential hypertension course and complications. A total of 87 subjects were examined, 23 of these--normal controls, 25 patients with myocardial infarction, 22 with angina pectoris, and 17 with essential hypertension. Solid-phase enzyme immunoassay was employed to detect anti-PGF2 alpha and anti-PGE2 antibodies. These antibodies were found in normal subjects, coronary patients and hypertensives. Blood levels of these antibodies correlated with some complications of coronary disease and essential hypertension. These results permit a hypothesis that the pathogenetic physiologic role of the detected natural antibodies to prostaglandins consists in their defense homeostatic function.</p>","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13022073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Results of follow-up of patients with diabetes mellitus type 1].","authors":"L S Namazova, E V Antonova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13031501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Available are the results of treatment of 104 females suffering from spontaneous cyclic abdominal pain. Clinical and paraclinical evaluation shows that sensibilization to certain estrogen fraction in the presence of estrogen-progesterone++ imbalance plays the leading role in pathogenesis of cyclic (phase I, II and in the middle of the cycle) abdominal pain. Desensitization by intracutaneous introduction of relevant estrogen fraction combined with progesterone++ provides recovery of vegetative and estrogen-progesterone++ balance, relief of pain and emotional stress. A complete response was achieved in 64.4%, partial in 25%, no response in 10.6% of the patients. Follow-up lasted for 1 to 17 years. Additional rehabilitation measures are suggested. The diagnosis and treatment were performedon the outpatient basis.
{"title":"[Principles of pathogenetic treatment of spontaneous cyclic abdominal pain in women].","authors":"E M Govorukhina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Available are the results of treatment of 104 females suffering from spontaneous cyclic abdominal pain. Clinical and paraclinical evaluation shows that sensibilization to certain estrogen fraction in the presence of estrogen-progesterone++ imbalance plays the leading role in pathogenesis of cyclic (phase I, II and in the middle of the cycle) abdominal pain. Desensitization by intracutaneous introduction of relevant estrogen fraction combined with progesterone++ provides recovery of vegetative and estrogen-progesterone++ balance, relief of pain and emotional stress. A complete response was achieved in 64.4%, partial in 25%, no response in 10.6% of the patients. Follow-up lasted for 1 to 17 years. Additional rehabilitation measures are suggested. The diagnosis and treatment were performedon the outpatient basis.</p>","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13031625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Extending the diagnostic possibilities of tetrapolar chest rheography].","authors":"V I Berezutskiĭ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13031634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M A Gurevich, N P Paleev, V A Odinokova, V B Smirnov, M O Iankovskaia
The paper presents the results of a clinicomorphological study of 50 patients with dilated cardiomyopathy. ECG, echocardiography, x-ray revealed atrial fibrillation, parasystole, extrasystole, impairment of intraventricular conduction, symptoms of a focal cicatricial myocardial lesion, high end-systolic and end-diastolic volumes, reduced ejection fraction, marked axial dilatation of the heart. Morphologic evaluation showed diffuse and diffuse microfocal cardiosclerosis, combination of sites of hypertrophic myocardiocytes with dystrophic foci, atrophy, sclerosis. Morphological evidence is available for arrhythmic, cardiomegalic, aneurysmic, infarction-like and pseudovalvular dilated cardiomyopathy.
{"title":"[Clinico-morphological characteristics of dilated cardiomyopathy].","authors":"M A Gurevich, N P Paleev, V A Odinokova, V B Smirnov, M O Iankovskaia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The paper presents the results of a clinicomorphological study of 50 patients with dilated cardiomyopathy. ECG, echocardiography, x-ray revealed atrial fibrillation, parasystole, extrasystole, impairment of intraventricular conduction, symptoms of a focal cicatricial myocardial lesion, high end-systolic and end-diastolic volumes, reduced ejection fraction, marked axial dilatation of the heart. Morphologic evaluation showed diffuse and diffuse microfocal cardiosclerosis, combination of sites of hypertrophic myocardiocytes with dystrophic foci, atrophy, sclerosis. Morphological evidence is available for arrhythmic, cardiomegalic, aneurysmic, infarction-like and pseudovalvular dilated cardiomyopathy.</p>","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13037037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Early active detection of proctologic diseases using a system of step-by-step automated screening].","authors":"M P Vilianskiĭ, A A Chumakova, A N Chekarin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13037799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blood lymphocyte redox enzymes were examined in 102 patients with infectious allergic myocarditis and vegetative dyshormonal +myocardial dystrophy. Dehydrogenase activity was found shifted and cellular energy balance disordered, these factors being valuable for differential diagnosis. Estimation of the lymphocytic energy plastic coefficient permits a dynamic monitoring of patient's status and helps predict the outcome of rehabilitation process. The detected metabolic shifts prompted inclusion of ++pyridoxal phosphate, a new coenzymic drug, in complex of treatment of this patient population.
{"title":"[Cytochemical parameters of lymphocytes in non-coronarogenic myocardial diseases].","authors":"A F Mazurets, V F Kubyshkin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Blood lymphocyte redox enzymes were examined in 102 patients with infectious allergic myocarditis and vegetative dyshormonal +myocardial dystrophy. Dehydrogenase activity was found shifted and cellular energy balance disordered, these factors being valuable for differential diagnosis. Estimation of the lymphocytic energy plastic coefficient permits a dynamic monitoring of patient's status and helps predict the outcome of rehabilitation process. The detected metabolic shifts prompted inclusion of ++pyridoxal phosphate, a new coenzymic drug, in complex of treatment of this patient population.</p>","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13044294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sucralfate and alsucral in the treatment of uncomplicated duodenal ulcer].","authors":"S A Cherniakevich, E O Borisova, I V Babkova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13044303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D B Tsykin, N A Lantsova, Iu V Shcherba, A G Velichko, E V Esaulenko, G A Tsykina, S M Tikhomirov
{"title":"[Changes in internal organs in narcotic and drug dependence].","authors":"D B Tsykin, N A Lantsova, Iu V Shcherba, A G Velichko, E V Esaulenko, G A Tsykina, S M Tikhomirov","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22244,"journal":{"name":"Sovetskaia meditsina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13044307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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