The Egyptian Journal of Bronchology最新文献

To the Editor,

Kaddah and colleagues [1] in their recently released study, employed metabolic syndrome definition elements (MetSDE) of the International Diabetes Federation (IDF) to study MetS prevalence and its predictors in Egyptian patients with obstructive sleep apnea (OSA). They found that 66.3% of OSA patients exhibited MetS and the relevant MetS predictors were SPO2 < 90%, body mass index, and neck, hip, and waist circumferences [1]. In addition to the few limitations addressed by Kaddah and colleagues [1], we present a noteworthy limitation, which is linked to MetSDE employed in the research. The optimum definition of MetS remains controversial. Over several years, numerous MetS definitions have been developed by scientific bodies. Though these definitions vary to some degree in their elements and threshold values, they generally endorse the essential parameters of the syndrome, notably abdominal obesity, dyslipidemia, hypertension, and insulin resistance. In research and clinical fields, numerous MetSDE are usually used such as IDF, American Heart Association (AHA), adult treatment panel-III (ATP-III), and finally joint interim statement (JIS). There is a significant conflicting agreement on the accuracy of these MetSDE for MetS characterization as noticed by numerous observational studies [2, 3]. Different results were obtained when measuring MetS prevalence among adult Egyptians using various MetSDE, namely 44.3% (IDF elements), 43.8% (AHA elements), 42.5% (ATP-III elements), and 41.5% (JIS elements with Egyptian cut-offs) [4]. To overcome the variations in estimating MetS prevalence by using different MetSDE, numerous nations have developed their diagnostic MetSDE and proved effective in yielding validated results in research and practice [5, 6]. The formulation of the Egyptian MetSDE is deemed critical as it can measure more readily MetS prevalence in OSA patients. Regardless of the study limitations, the recorded MetS prevalence in the studied OSA patients (66.3%) [1] is troublesome and it calls for the urgent implementation of strategic interventions to lessen the negative health effects of MetS, decrease healthcare visits and costs, and improve OSA patients’ quality of life.

IDF:

International Diabetes Federation

OSA:

Obstructive sleep apnea

MetS:

Metabolic syndrome

MetSDE:

MetS definition elements

AHA:

American Heart Association

ATP-III:

Adult Treatment Panel-III

JI:

Joint Interim Statement

1. 致编辑：Kaddah 及其同事[1]在最近发表的研究中采用了国际糖尿病联合会（IDF）的代谢综合征定义要素（MetSDE），研究了埃及阻塞性睡眠呼吸暂停（OSA）患者的 MetS 患病率及其预测因素。他们发现，66.3% 的 OSA 患者表现出 MetS，相关 MetS 预测因子为 SPO2 &lt;90%、体重指数以及颈围、臀围和腰围[1]。除了 Kaddah 及其同事[1]提到的几个局限性外，我们还提出了一个值得注意的局限性，这与研究中采用的 MetSDE 有关。MetS 的最佳定义仍存在争议。几年来，科学机构制定了许多 MetS 定义。尽管这些定义在要素和临界值上存在一定程度的差异，但它们普遍认可该综合征的基本参数，尤其是腹部肥胖、血脂异常、高血压和胰岛素抵抗。在研究和临床领域，通常使用许多 MetSDE，如 IDF、美国心脏协会 (AHA)、成人治疗小组-III (ATP-III)，以及最后的联合临时声明 (JIS)。许多观察性研究[2, 3]发现，这些 MetSDE 对 MetS 特征描述的准确性存在明显的分歧。在使用各种 MetSDE 测量成年埃及人的 MetS 患病率时，得到了不同的结果，即 44.3%（IDF 要素）、43.8%（AHA 要素）、42.5%（ATP-III 要素）和 41.5%（JIS 要素与埃及截止值）[4]。为了克服使用不同的 MetSDE 估算 MetS 患病率时的差异，许多国家都开发了自己的诊断 MetSDE，并在研究和实践中证明能有效地得出有效结果[5, 6]。埃及 MetSDE 的制定被认为至关重要，因为它能更容易地测量 OSA 患者的 MetS 患病率。尽管研究存在局限性，但所研究的 OSA 患者中记录的 MetS 患病率（66.3%）[1] 仍令人担忧，这就要求紧急实施战略性干预措施，以减轻 MetS 对健康的负面影响、减少医疗就诊次数和费用，并提高 OSA 患者的生活质量。IDF：国际糖尿病联合会OSA：阻塞性睡眠呼吸暂停MetS：代谢综合征MetSDE：代谢综合征定义要素AHA：美国心脏协会ATP-III：成人治疗小组-IIIJI：联合临时声明Kaddah SZ，Korany MH，Ibrahim EK（2024 年）阻塞性睡眠呼吸暂停患者代谢综合征的临床特征和预测因素。Egypt J Bronchol 18:6Article Google Scholar Nwankwo M, Okamkpa CJ, Danborno B (2022) Comparison of diagnostic criteria and prevalence of metabolic syndrome using WHO, NCEP-ATP III, IDF and harmonized criteria: a case study from urban southeast Nigeria.Diabetes Metab Syndr 16（12）：102665Article CAS PubMed Google Scholar de Almeida MD, Dos Santos AM, da Cruz Silveira VN, Silva MB, da Silva DA (2023) Prevalence of metabolic syndrome in adolescents based on three diagnostic definitions: a crosssectional study.Arch Endocrinol Metab 67(5):e000634Article Google Scholar Assaad-Khalil SH, Mikhail MM, Aati TA, Zaki A, Helmy MA, Megallaa MH et al (2015) 在埃及成年人群中确定腹部肥胖和检测心血管风险因素的最佳腰围临界点。Indian J Endocrinol Metab 19(6):804-810Article CAS PubMed PubMed Central Google Scholar Ding Z, Pi F, Zhang S, Dong W, Wen Y, Wu J, Zhang Q (2016) Establishment and application of a new diagnostic definition of metabolic syndrome in the Shantou region of southern China.Sci Rep 6:22210Article CAS PubMed PubMed Central Google Scholar Yamagishi K, Iso H (2017) The criteria for metabolic syndrome and the national health screening and education system in Japan.Epidemiol Health 39:e2017003Article PubMed PubMed Central Google Scholar 下载参考文献不适用未收到来自公共、商业或非营利部门资助机构的特定资助。作者和工作单位伊拉克巴格达，巴格达大学 Al-Kindy 医学院儿科Mahmood D. Al-Mendalawi巴格达邮局，P.O.Box 55302，伊拉克巴格达Mahmood D. Al-Mendalawi作者Mahmood D. Al-MendalawiAl-Mendalawi查看作者发表的文章您也可以在PubMed谷歌学术中搜索该作者贡献MDA阅读了有关代谢综合征和阻塞性睡眠呼吸暂停的文献，撰写了手稿，并批准了手稿。同意发表不适用.利益冲突MDA声明他没有利益冲突.出版商注释Springer Nature对出版地图中的管辖权主张和机构隶属关系保持中立.开放获取本文采用知识共享署名4.0.0.0许可协议进行许可。 创作共用 "许可协议允许以任何媒介或格式使用、共享、改编、分发和复制文章，但必须注明原作者和出处，提供指向 "创作共用 "许可协议的链接，并说明是否进行了修改。本文中的图片或其他第三方材料均包含在文章的知识共享许可协议中，除非在材料的署名栏中另有说明。如果材料未包含在文章的知识共享许可协议中，且您打算使用的材料不符合法律规定或超出许可使用范围，您需要直接从版权所有者处获得许可。要查看该许可的副本，请访问 http://creativecommons.org/licenses/by/4.0/.Reprints and permissionsCite this articleAl-Mendalawi, M.D. Clinical features and predictors of metabolic syndrome among obstructive sleep apnea patients.Egypt J Bronchol 18, 42 (2024). https://doi.org/10