Fine tuning and switching of nonlinear optical response of ferrocene chromophores has been an area of considerable significance as evidenced by a large number of reports in the current literature. In this personal account, we present linear/nonlinear behavior and structure‐activity relationships of several classes of donor‐π‐acceptor designs using organometallic and organic materials, developed by our research group during the last decade. The results especially the electronic absorption spectral and the hyper‐Rayleigh scattering have been supported by theoretical calculations. Exploiting the redox behavior of ferrocene donor, we have demonstrated switching of quadratic nonlinear optical responses with reversible redox chemistry, which is a useful attribute of nonlinear optical materials. Based on the ease in synthesis, structure diversification and structure‐based large and switchable second‐order optical nonlinearity, these materials are potential candidates for electro‐optic applications.
{"title":"Second‐order nonlinear polarizability of “Push‐Pull” chromophores. A decade of progress in donor‐π‐acceptor materials","authors":"P. Kaur, Kamaljit Singh","doi":"10.1002/tcr.202200024","DOIUrl":"https://doi.org/10.1002/tcr.202200024","url":null,"abstract":"Fine tuning and switching of nonlinear optical response of ferrocene chromophores has been an area of considerable significance as evidenced by a large number of reports in the current literature. In this personal account, we present linear/nonlinear behavior and structure‐activity relationships of several classes of donor‐π‐acceptor designs using organometallic and organic materials, developed by our research group during the last decade. The results especially the electronic absorption spectral and the hyper‐Rayleigh scattering have been supported by theoretical calculations. Exploiting the redox behavior of ferrocene donor, we have demonstrated switching of quadratic nonlinear optical responses with reversible redox chemistry, which is a useful attribute of nonlinear optical materials. Based on the ease in synthesis, structure diversification and structure‐based large and switchable second‐order optical nonlinearity, these materials are potential candidates for electro‐optic applications.","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84716796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MXenes have aroused widespread interest in the biomedical field owing to their remarkable photo‐thermal conversion capabilities combined with large specific surface areas. MXenes quantum dots (MQDs) have been synthesized either by the physical or chemical methods based on MXenes as precursors, which possess smaller size, higher photoluminescence, coupled with low cytotoxicity and many beneficial properties of MXenes, thereby having potential biomedical applications. Given this, this review summarized the synthesis methods, optical, surface and biological properties of MQDs along with their practical applications in the field of biomedicine. Finally, the authors make an outlook towards the synthesis, properties and applications of MQDs in the future biomedicine field.
{"title":"MXenes Quantum Dots for Biomedical Applications: Recent Advances and Challenges","authors":"Tiedong Sun, Minglu Tang, Yangtian Shi, Bin Li","doi":"10.1002/tcr.202200019","DOIUrl":"https://doi.org/10.1002/tcr.202200019","url":null,"abstract":"MXenes have aroused widespread interest in the biomedical field owing to their remarkable photo‐thermal conversion capabilities combined with large specific surface areas. MXenes quantum dots (MQDs) have been synthesized either by the physical or chemical methods based on MXenes as precursors, which possess smaller size, higher photoluminescence, coupled with low cytotoxicity and many beneficial properties of MXenes, thereby having potential biomedical applications. Given this, this review summarized the synthesis methods, optical, surface and biological properties of MQDs along with their practical applications in the field of biomedicine. Finally, the authors make an outlook towards the synthesis, properties and applications of MQDs in the future biomedicine field.","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85039987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Over the last twenty years, fluorination on nucleoside has established itself as the most promising tool to use to get biologically active compounds that could sustain the clinical trial by affecting the pharmacodynamics and pharmacokinetic properties. Due to fluorine's inherent unique properties and its judicious introduction into the molecule, makes the corresponding nucleoside metabolically very stable, lipophilic, and opens a new site of intermolecular binding. Fluorination on various nucleosides has been extensively studied as a result, a series of fluorinated nucleosides come up for different therapeutic uses which are either approved by the FDA or under the advanced stage of the clinical trial. Here in this review, we are summarizing the latest development in the chemistry of fluorination on nucleoside that led to varieties of new analogs like carbocyclic, acyclic, and conformationally biased nucleoside and their biological properties, the influence of fluorine on conformation, oligonucleotide stability, and their use in therapeutics.
{"title":"Fluorinated Nucleosides: Synthesis, Modulation in Conformation and Therapeutic Application","authors":"Shantanu Pal, Girish Chandra, Samridhi Patel, Sakshi Singh","doi":"10.1002/tcr.202100335","DOIUrl":"https://doi.org/10.1002/tcr.202100335","url":null,"abstract":"Over the last twenty years, fluorination on nucleoside has established itself as the most promising tool to use to get biologically active compounds that could sustain the clinical trial by affecting the pharmacodynamics and pharmacokinetic properties. Due to fluorine's inherent unique properties and its judicious introduction into the molecule, makes the corresponding nucleoside metabolically very stable, lipophilic, and opens a new site of intermolecular binding. Fluorination on various nucleosides has been extensively studied as a result, a series of fluorinated nucleosides come up for different therapeutic uses which are either approved by the FDA or under the advanced stage of the clinical trial. Here in this review, we are summarizing the latest development in the chemistry of fluorination on nucleoside that led to varieties of new analogs like carbocyclic, acyclic, and conformationally biased nucleoside and their biological properties, the influence of fluorine on conformation, oligonucleotide stability, and their use in therapeutics.","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"139 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80409062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Several forerunners to the Woodward‐Hoffmann rules appear in the chemical literature in the early 1960s. While these precedents refer to orbital symmetry and explain either electrocyclic reactions (Luitzen Oosterhoff, cited by Egbert Havinga and Jos Schlatmann in Tetrahedron in 1961) or some cycloaddition reactions (Kenichi Fukui, in a book chapter published in 1964), they did not attract any attention and did not serve to initiate any research prior to the publication of the five Woodward and Hoffmann communications in 1965. Even Woodward and Hoffmann were unaware of these precedents (though Hoffmann knew of Fukui's frontier orbital theory) until after they had completed the relevant portions of their work. The Oosterhoff‐Havinga‐Schlatmann story will be told in this paper; the Fukui story will be told in the next paper in this series on the history of the development of the Woodward‐Hoffmann rules. Explanations for these precedents not being productive in solving the no‐mechanism problem are discussed.
{"title":"Sleeping Beauties in Chemistry. Oosterhoff, Havinga and Schlatmann: Four Years Before “The Woodward‐Hoffmann Rules”† **","authors":"J. I. Seeman","doi":"10.1002/tcr.202100245","DOIUrl":"https://doi.org/10.1002/tcr.202100245","url":null,"abstract":"Several forerunners to the Woodward‐Hoffmann rules appear in the chemical literature in the early 1960s. While these precedents refer to orbital symmetry and explain either electrocyclic reactions (Luitzen Oosterhoff, cited by Egbert Havinga and Jos Schlatmann in Tetrahedron in 1961) or some cycloaddition reactions (Kenichi Fukui, in a book chapter published in 1964), they did not attract any attention and did not serve to initiate any research prior to the publication of the five Woodward and Hoffmann communications in 1965. Even Woodward and Hoffmann were unaware of these precedents (though Hoffmann knew of Fukui's frontier orbital theory) until after they had completed the relevant portions of their work. The Oosterhoff‐Havinga‐Schlatmann story will be told in this paper; the Fukui story will be told in the next paper in this series on the history of the development of the Woodward‐Hoffmann rules. Explanations for these precedents not being productive in solving the no‐mechanism problem are discussed.","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91010378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover Picture: Nanographene – A Scaffold of Two‐Dimensional Materials (Chem. Rec. 3/2022)","authors":"R. Sekiya, T. Haino","doi":"10.1002/tcr.202280301","DOIUrl":"https://doi.org/10.1002/tcr.202280301","url":null,"abstract":"","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89616095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover Feature: Taming Electron Transfers: From Breaking Bonds to Creating Molecules (Chem. Rec. 9/2021)","authors":"N. Wolff, M. Robert","doi":"10.1002/tcr.202180902","DOIUrl":"https://doi.org/10.1002/tcr.202180902","url":null,"abstract":"","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"126 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79528015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover Feature: Multi‐Redox Active Carbons and Hydrocarbons: Control of their Redox Properties and Potential Applications (Chem. Rec. 9/2021)","authors":"H. Ueda, Soichiro Yoshimoto","doi":"10.1002/tcr.202180903","DOIUrl":"https://doi.org/10.1002/tcr.202180903","url":null,"abstract":"","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87136401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. M. Kisukuri, Vitor A. Fernandes, José A. C. Delgado, Andreas P Häring, M. Paixão, S. R. Waldvogel
{"title":"Cover Feature: Electrochemical Installation of CFH\u0000 2\u0000 −, CF\u0000 2\u0000 H−, CF\u0000 3\u0000 −, and Perfluoroalkyl Groups into Small Organic Molecules (Chem. Rec. 9/2021)","authors":"C. M. Kisukuri, Vitor A. Fernandes, José A. C. Delgado, Andreas P Häring, M. Paixão, S. R. Waldvogel","doi":"10.1002/tcr.202180905","DOIUrl":"https://doi.org/10.1002/tcr.202180905","url":null,"abstract":"","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84606442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover Picture: Bioinspired Electrolysis for Green Molecular Transformations of Organic Halides Catalyzed by B\u0000 12\u0000 Complex (Chem. Rec. 9/2021)","authors":"H. Shimakoshi, Y. Hisaeda","doi":"10.1002/tcr.202180901","DOIUrl":"https://doi.org/10.1002/tcr.202180901","url":null,"abstract":"","PeriodicalId":22443,"journal":{"name":"The Chemical Record","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87941597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：