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Short-term outcomes of intracorporeal versus extracorporeal ileotransverse anastomosis in laparoscopic right colectomy: A prospective randomized study 腹腔镜右结肠切除术中体外回肠吻合术与体外回肠吻合术的短期疗效:前瞻性随机研究
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357128
Ahmed Aly Khalil, Kareem Gamal, Tarek Yousef, Mohamed Gouda, Kareem Kamel
Background: Laparoscopic right colectomy is a widely accepted surgical technique for colon cancer resection, commonly using either intracorporeal anastomosis (ICA) or extracorporeal anastomosis (ECA). Our study compares the benefits of ICA versus ECA, as ICA has been suggested to provide faster recovery and shorter hospital stays. However, there is a lack of scientific evidence in this regard. Patients and Methods: An randomized clinical trial was conducted from November 2021 to June 2023 to compare intraoperative technical events and short-term postoperative clinical outcomes. Results: A total of 71 were randomized. The median operative time for the ECA group was 226.67 min (range: 167–310) and 222.78 min for the ICA group (range: 158–263) with no significant difference between them ( P=0.606 ). There is no significant difference in the number of harvested lymph nodes between the ECA group (mean: 13.88, range: 12–15) and the ICA group (mean: 13.78, range: 12–16) ( P=0.664 ). The incidence of postoperative ileus, vomiting, and intestinal obstruction did not differ significantly between the two groups ( P=0.728 , 0.795, and 0.885, respectively). Significantly, there was a higher incidence of wound infection in the ECA group ( P=0.047 ). The ICA group had significantly lower pain scale scores on the postoperative day ( P<0.001 ). Significantly shorter mean length of postoperative hospital stays was seen in the ICA group (4.15 vs. 5.27 for ECA, P<0.001 ). Delayed postoperative complications showed no significant difference ( P=0.061 and 0.362 for incisional hernia and internal hernia, respectively). Conclusion: ICA has less postoperative pain, shorter time to first flatus, shorter length of hospital stays, and lower rates of wound infection with nearly the same operative time compared with ECA.
背景:腹腔镜右结肠切除术是一种广为接受的结肠癌切除手术技术,通常采用体腔内吻合术(ICA)或体外吻合术(ECA)。我们的研究比较了 ICA 和 ECA 的优势,因为 ICA 被认为能提供更快的恢复和更短的住院时间。然而,目前还缺乏这方面的科学证据。患者和方法:2021 年 11 月至 2023 年 6 月期间进行了一项随机临床试验,比较术中技术事件和术后短期临床结果。结果共有 71 人参与了随机试验。ECA 组的中位手术时间为 226.67 分钟(范围:167-310),ICA 组为 222.78 分钟(范围:158-263),两者之间无显著差异(P=0.606)。ECA 组(平均:13.88,范围:12-15)和 ICA 组(平均:13.78,范围:12-16)收获的淋巴结数量无明显差异(P=0.664)。术后回肠梗阻、呕吐和肠梗阻的发生率在两组之间没有显著差异(分别为 P=0.728 、0.795 和 0.885)。值得注意的是,ECA 组的伤口感染发生率更高(P=0.047)。ICA组术后当天的疼痛量表评分明显较低(P<0.001)。ICA组的术后平均住院时间明显更短(ECA组为4.15天,而ICA组为5.27天,P<0.001)。术后延迟并发症无明显差异(切口疝和内疝的差异分别为 P=0.061 和 0.362)。结论与 ECA 相比,ICA 术后疼痛更轻,首次排气时间更短,住院时间更短,伤口感染率更低,而手术时间几乎相同。
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引用次数: 0
Comparative research for surgical excision and lay-open maneuver in treatment of hand and wrist ganglion cyst 手部和腕部神经节囊肿手术切除与平卧位手术治疗的比较研究
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357106
Yahya Kamal
Target: The goal of the study was to compare the outcomes of two different approaches to treating hand and wrist ganglia: the lay-open procedure and typical surgical excision. Patients and Methods: This study was conducted at the surgery department of the Alqureen General Hospital in Sharkia, Egypt, between January and December of 2023. This survey was completed by 40 individuals who had wrist or hand ganglions. Patients were divided into two categories based on casual distribution. Traditional surgical excision was used to treat one kind (group A), whereas a lay-open technique was used to treat the other kind (group B). Recurrences were noted during the 6-month proceedings for both. Results: The typical surgical excision took much longer to complete (61.2 vs. 23.7 min; P<0.001 ) than the lay-open procedure. There was a considerable variance between the two sorts with relation to the operating maneuver complexity ( P<0.001 ). Group A experienced more satisfied postoperative complications. However, when it came to wound infection and the appearance of minor postoperative discomfort, the difference between the two types was not statistically significant ( P=0.3 ). Patients in type B reported higher levels of satisfaction (90 vs. 45%; P<0.001 ). Conclusion: When compared with typical surgical excision for the treatment of hand and wrist ganglion cysts, the lay-open procedure appears to be preferable.
目标该研究的目的是比较两种不同的手部和腕部神经节治疗方法的效果:平卧开颅术和典型的手术切除术。患者和方法:本研究于 2023 年 1 月至 12 月期间在埃及沙尔基亚的 Alqureen 综合医院外科进行。这项调查由 40 名患有腕部或手部神经节的患者完成。根据患者的分布情况,将其分为两类。其中一类(A 组)采用传统手术切除术,另一类(B 组)采用非开放技术。在为期 6 个月的治疗过程中,对两组患者的复发情况进行了记录。结果显示典型的外科切除术比非开放手术耗时更长(61.2 分钟对 23.7 分钟;P<0.001)。在手术操作的复杂程度上,两组之间存在相当大的差异(P<0.001)。A组术后并发症的满意度更高。然而,在伤口感染和术后出现轻微不适方面,两种类型之间的差异没有统计学意义(P=0.3)。B 组患者的满意度更高(90% 对 45%;P<0.001)。结论:与治疗手部和腕部神经节囊肿的典型手术切除术相比,非开腹手术似乎更为可取。
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引用次数: 0
Safety and efficacy of laparoscopic sleeve gastrectomy in elderly patients: A matched case-control study 老年患者腹腔镜袖带胃切除术的安全性和有效性:匹配病例对照研究
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357119
Hosam B. Barakat, Ahmed Badran, Mohamed Elsheikh
Background: Despite the increasing prevalence of obesity among elderly individuals, there is ongoing debate regarding the safety of bariatric procedures in this age group. Objective: This study aimed to assess the efficacy and safety of laparoscopic sleeve gastrectomy (LSG), specifically in patients aged 55 years and older. Patients and Methods: A retrospective analysis was performed on patients subjected to LSG in our institution from 2019 to 2023. Forty elderly patients more than or equal to 55 years were included (study group) and were matched with forty younger patients (control group) based on BMI, sex, and comorbidities distribution. The study compared short-term outcomes regarding weight loss, comorbidities improvement, operative time, hospital stay, and complications. Results: There were no significant differences regarding the demographic characteristics or preoperative comorbidities distribution within the two groups. The mean operative time was slightly longer in the older patients than in the control group (53.85±12.17 vs. 49.25±16.22 min, respectively), but with no statistical significance. There was no perioperative mortality in both groups. The percent excess weight loss at 1 year for the older group was significantly lower than that for the younger group (58.1 vs. 68.74%. respectively). Most comorbidities in both groups were improved or resolved with no significant statistical. The morbidity rate was 15 and 17.5% for the elderly and the younger group, respectively, with no significant difference. Conclusion: LSG is safe and effective in patients more than or equal to 55 years and presents a valuable bariatric option that is efficient in inducing weight loss and improving obesity-related comorbidities and is associated with an acceptable morbidity rate comparable to younger populations.
背景:尽管肥胖症在老年人中的发病率越来越高,但关于在这一年龄组中进行减肥手术的安全性却一直存在争议。研究目的本研究旨在评估腹腔镜袖带胃切除术(LSG)的疗效和安全性,尤其是 55 岁及以上患者的疗效和安全性。患者和方法:对本机构 2019 年至 2023 年期间接受 LSG 的患者进行回顾性分析。根据体重指数(BMI)、性别和合并症分布,纳入 40 名大于或等于 55 岁的老年患者(研究组),并与 40 名年轻患者(对照组)进行配对。研究比较了体重减轻、合并症改善、手术时间、住院时间和并发症等方面的短期结果。研究结果两组患者的人口统计学特征和术前合并症分布无明显差异。老年患者的平均手术时间略长于对照组(分别为(53.85±12.17)分钟和(49.25±16.22)分钟),但无统计学意义。两组患者均无围术期死亡率。老年组 1 年后的超重百分比明显低于年轻组(分别为 58.1% 对 68.74%)。两组患者的大多数合并症都得到了改善或解决,无明显统计学差异。老年组和年轻组的发病率分别为 15% 和 17.5%,无明显差异。结论LSG对55岁以上的患者安全有效,是一种有价值的减肥方法,能有效减轻体重,改善肥胖相关的合并症,其发病率与年轻人相当,可以接受。
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引用次数: 0
Comparative study for the outcome of living donor liver transplantation in patients with portal vein thrombosis in comparison to patients without portal vein thrombosi 门静脉血栓患者与无门静脉血栓患者活体肝移植疗效比较研究
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.274273.1008
Muhammad Musalam, Amr Abdel Nasser, Amro Abdelaal, Ahmed Khalil, H. S. Saber
Background: Portal vein thrombosis (PVT) is a relative contraindication in living donor liver transplantation (LDLT). We monitored the outcome of adult patients with PVT in comparison to patients without PVT in LDLT.. Methods: This study is a retrospective cohort study. LDLTs that were performed at Liver Transplantation Unit in Air Forces Hospital and Nasser Institute, between January 2016 and June 2022 were evaluated. 176 cases were divided into two groups according to the presence of PVT, group A included 55 recipients who had PVT compared with group B including 121 recipients without PVT.. Results: In our study (N = 176), postoperative PV complications was recorded in 11 (6.3 %) cases. Five case in each group had postoperative PVT (9.8 % vs. 4.1 %), respectively and a single case of PV stenosis (0.8 %) was documented in non-PVT group. All patients who develop early postoperative PV (n = 3/10) complications unfortunately died because of it, unlike those who developed late PV complications, their 1 year survival rate was 70 % of cases and the overall mortality rate in patients developed PV complications was 40 %. Conclusion: PVT is established not to be a contraindication for LT but needs complex procedures and sophisticated techniques and Surgeons should be aware of these techniques to restore adequate portal flow in transplant for recipients with PVT.
背景:门静脉血栓(PVT)是活体肝移植(LDLT)的相对禁忌症。我们对患有门静脉血栓的成年患者与未患有门静脉血栓的成年患者在 LDLT 中的治疗效果进行了对比观察。方法:本研究是一项回顾性队列研究。研究评估了 2016 年 1 月至 2022 年 6 月期间在空军医院肝移植科和纳赛尔研究所进行的 LDLT。根据PVT的存在将176例患者分为两组,A组包括55例有PVT的受者,B组包括121例无PVT的受者。结果在我们的研究中(N = 176),有 11 例(6.3%)出现了术后静脉输液并发症。两组中分别有 5 例术后出现静脉血栓(9.8% 对 4.1%),非静脉血栓组中有一例静脉血管狭窄(0.8%)。所有术后早期出现 PV 并发症的患者(3/10)均不幸死亡,而术后晚期出现 PV 并发症的患者则不同,他们的 1 年存活率为 70%,出现 PV 并发症患者的总死亡率为 40%。结论PVT已确定不是LT的禁忌症,但需要复杂的手术和先进的技术,外科医生应了解这些技术,以便在移植中为PVT受者恢复充足的门静脉血流。
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引用次数: 0
Evaluation of the role of neoadjuvant chemotherapy in the management of rectal cancer 评估新辅助化疗在直肠癌治疗中的作用
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357107
Ahmed F. Elkased, Naser M Abdel Bary, Mohamed S. Amar, Sherif Y. Hassan, Galal M. Abdel Kawy, Mohamed H. Elmelegy
. ABSTRACT Background: The current standard of care for locally advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery. Recent research has highlighted the possible advantages of induction chemotherapy before concurrent Chemoradiotherapy (CRT) for individuals with locally advanced rectal cancer (LARC). Our research assesses the efficacy and viability of induction chemotherapy before concomitant chemoradiotherapy for locally advanced rectal cancer. Patients and Methods: Forty patients with locally advanced cancer rectum were enrolled in our study in 2019–2021. Initially, they underwent an induction chemotherapy regimen consisting of 3 cycles of FOLFOX (oxaliplatin, leucovorin, 5 fluorouracil) over 3 months. Response assessment of the patients was done by pelvic MRI. Concurrent chemoradiotherapy was given 2 weeks after completion of induction chemotherapy. Four weeks later, the patients were reassessed by pelvic MRI, computed tomography chest, and abdomen. Total mesorectal excision was performed at 6–8 weeks after the end of radiotherapy. Included patients were evaluated for pCR, Circumferential resection margins (CRM), RO resection, sphincter preservation, treatment toxicity, and postoperative morbidity and mortality. Results: In this study, sphincter preservation was achieved in eight out of 21 (38%) patients with low rectal tumors less than or equal to 5 cm who were candidates for Abdominoperineal resection (APR) and shifted to Anterior resection (AR); complete pathological response was achieved in seven (20.5%) patient; R0 resection was achieved in 34 (92%) patients; CRM was positive in three patients; two of them developed local recurrence and one of them developed distant metastasis. Conclusion: For locally
.摘要 背景:目前治疗局部晚期直肠癌的标准是先进行新辅助化放疗,然后再进行手术。最近的研究强调了局部晚期直肠癌(LARC)患者在同时接受化放疗(CRT)前接受诱导化疗可能具有的优势。我们的研究评估了局部晚期直肠癌患者在同时接受化放疗前进行诱导化疗的疗效和可行性。患者和方法:40 名局部晚期直肠癌患者于 2019-2021 年加入我们的研究。最初,他们接受了为期3个月的3个周期FOLFOX(奥沙利铂、白杉醇、5氟尿嘧啶)诱导化疗方案。患者的反应评估通过盆腔磁共振成像进行。诱导化疗结束两周后,同时进行放化疗。四周后,通过盆腔磁共振成像、胸部和腹部计算机断层扫描对患者进行再次评估。放疗结束后 6-8 周进行全直肠系膜切除术。对纳入患者的 pCR、环形切除边缘(CRM)、RO切除、括约肌保留、治疗毒性、术后发病率和死亡率进行了评估。结果:在这项研究中,21 例(38%)小于或等于 5 厘米的低位直肠肿瘤患者中,有 8 例(38%)实现了括约肌保留,这些患者都是腹会阴切除术(APR)的候选者,后转为前切除术(AR);7 例(20.5%)患者实现了完全病理反应;34 例(92%)患者实现了 R0 切除;3 例患者的 CRM 呈阳性;其中 2 例出现局部复发,1 例出现远处转移。结论对于局部
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引用次数: 0
Short-term outcome after Roux-en-Y gastric bypass for revision after failed sleeve gastrectomy versus De novo Roux-en-Y gastric bypass for bariatric patients 减肥患者袖状胃切除术失败后进行 Roux-en-Y 胃旁路术翻修与重新进行 Roux-en-Y 胃旁路术后的短期疗效比较
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.273846.1001
S. Saber, Tarek M. Sehsah, Mahmoud A. Eissa
Background: Revisional bariatric surgeries for weight regain are rising; however, they are considered as riskier and less efficient than primary bariatric procedures. This study aimed to study short-term postoperative outcomes after Roux-en-Y gastric bypass (RYGB) for revision after failed Sleeve gastrectomy versus primary RYGB in Bariatric patients regarding Weight loss, comorbidity resolution, Postoperative complications, hospital stay, mortality, and readmissions. Patients and Methods: This retrospective study was designed to compare early postoperative outcome between 2 groups of patients admitted to General Surgery Department, Tanta University Hospitals during the period from June 2018 and June 2023. Results: A total of 254 patients were included in the study, with 87 patients in revisional RYGB and 167 patients in primary RYGB. Groups were matched for age, sex, smoking, preoperative weight, and comorbidities. The duration of revisional RYGB was significantly longer than primary RYGB (201.1±49.85 vs. 161.9±45.05; P <0.001 ). Revisional RYGB patients stayed longer in the hospital (2.54±0.74 vs. 1.87±0.78; P <0.001 ). Total weight loss was significantly higher after 6 months and 1 year in Primary RYGB than group revisional RYGB ( P value<0.05 ). However, no differences were detected in postoperative complications, readmissions, reoperation rates, and comorbidity resolution. Conclusion: RYGB as revisional surgery after a previous Sleeve gastrectomy is a complex procedure that must be indicated with care. It is a safe technique, with postoperative complication rates similar to those of primary RYGB, while it may need longer operative
背景:因体重反弹而进行的翻修减肥手术正在增加;然而,与初次减肥手术相比,这些手术被认为风险更高、效率更低。本研究旨在研究减肥患者在袖带胃切除术失败后进行Roux-en-Y胃旁路术(RYGB)翻修与初治RYGB术后的短期疗效,包括体重减轻、合并症缓解、术后并发症、住院时间、死亡率和再住院率。患者和方法:这项回顾性研究旨在比较坦塔大学医院普外科在 2018 年 6 月至 2023 年 6 月期间收治的两组患者的早期术后效果。结果:研究共纳入 254 名患者,其中 87 名患者为翻修 RYGB 患者,167 名患者为初次 RYGB 患者。两组患者的年龄、性别、吸烟、术前体重和合并症均匹配。翻修RYGB的持续时间明显长于初治RYGB(201.1±49.85 vs. 161.9±45.05;P <0.001 )。改良 RYGB 患者的住院时间更长(2.54±0.74 vs. 1.87±0.78;P <0.001 )。初治 RYGB 患者 6 个月和 1 年后的总重量下降明显高于复治 RYGB 组(P<0.05)。然而,在术后并发症、再入院率、再次手术率和合并症缓解率方面没有发现差异。结论RYGB 作为既往袖带胃切除术后的翻修手术是一项复杂的手术,必须谨慎对待。它是一种安全的技术,术后并发症发生率与初治 RYGB 相似,但可能需要更长的手术时间。
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引用次数: 0
Value of drain in reduction of seroma and wound infection in Lichtenstein repair of inguinal hernia 引流管在减少腹股沟疝 Lichtenstein 修补术中血清肿和伤口感染方面的价值
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357126
M. Mohamed, Mohamed M. Mahmoud, Mohamed A. AbdElhady
Background: In Egypt, open Lichtenstein mesh repair is the standard management option for symptomatic unilateral inguinal hernia. The use of drains is routinely done by many surgeons after such procedures with no proven evidence of their benefits and complications. That motivated us to conduct the present study to evaluate the value of drain insertion in such patients. Patients and Methods: The data of 60 consecutive patients (30 patients in the drain group and another 30 patients in the drainless group) diagnosed with unliteral inguinal hernia and underwent open Lichtenstein hernioplasty were retrospectively reviewed. The main outcome was the incidence of postoperative adverse events, mainly seroma, hematoma, and wound infection. Results: Our analysis revealed no notable differences between the drain and drainless groups regarding patient and hernia characteristics. The operative time and hospitalization period were also statistically comparable. The incidence of postoperative complications did not show noteworthy differences between the two approaches. The incidence of wound infection was similar in both groups (3.3%). Seroma occurred in only one (3.3%) patient in the drainless group. Hematoma occurred in 3.3% of drain cases and 6.7% of drainless cases. Moreover, wound edema was encountered in 6.7 and 13.3% of cases in the same groups, respectively. No patients developed recurrence during the 1-year follow-up period. Conclusion: The use of drains is not associated with significant protective effects against posthernioplasty complications. Its use should be individualized to decrease the impact of drain-associated complications.
背景:在埃及,开放式 Lichtenstein 网片修补术是治疗无症状单侧腹股沟疝的标准方法。许多外科医生在此类手术后都会常规使用引流管,但没有证据证明引流管的益处和并发症。这促使我们开展本研究,以评估在此类患者中插入引流管的价值。患者和方法:我们回顾性分析了60例连续接受开放式Lichtenstein疝成形术的无腹股沟疝患者(引流管组30例,无引流管组30例)的数据。主要结果是术后不良事件的发生率,主要是血清肿、血肿和伤口感染。结果:我们的分析表明,引流管组和无引流管组在患者和疝气特征方面没有明显差异。手术时间和住院时间在统计学上也具有可比性。两种方法的术后并发症发生率没有明显差异。两组的伤口感染发生率相似(3.3%)。无引流管组仅有一名患者(3.3%)出现血清肿。3.3%的引流管病例和6.7%的无引流管病例出现血肿。此外,两组患者中分别有 6.7% 和 13.3% 出现伤口水肿。在为期一年的随访期间,没有患者复发。结论使用引流管对疝成形术后并发症的保护作用并不明显。引流管的使用应因人而异,以减少引流管相关并发症的影响。
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引用次数: 0
Trial of thyroid auto-transplantation after total thyroidectomy in benign thyroid diseases 良性甲状腺疾病患者甲状腺全切除术后的甲状腺自体移植试验
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357141
Mohamed Salah El-din, Hesham Adel Alaa, Ayman Hossam Eldin, Ahmed Saeed Saad
Background: Thyroid auto transplantation was introduced after the success of parathyroid auto transplantation. Heterotopic thyroid autotransplantation is a technique that preserves viable thyroid tissue in the body after total thyroidectomy, which may revascularize and restore thyroid function. Thyroid autotransplantation can help avoid lifetime thyroid hormone replacement therapy, which may have some drawbacks such as disruption of lipid metabolism, coronary heart disease, non-compliance, and malabsorptionThyroid autotransplantation can also preserve the inner auto-regulatory mechanism of thyroid hormone production, which can adjust to the body’s needsThyroid autotransplantation can prevent reoperation at the site of previous neck surgery in cases of recurrent goiters or hyperthyroidism, which can be associated with a high rate of complications. heterotopic thyroid autotransplantation is still not a popular technique and there is limited data on its long-term outcomes and safety. Some studies have reported satisfactory results in terms of survival and function of the thyroid implant, but the number of patients and the follow-up periods were very low. There are also some challenges and controversies regarding the optimal site, size, and number of the grafts, as well as the indications and contraindications of this procedure.
背景:甲状腺自体移植是在甲状旁腺自体移植取得成功后引入的。异位甲状腺自体移植是一种在甲状腺全切除术后保留体内有活力的甲状腺组织的技术,可使甲状腺组织血管再通并恢复甲状腺功能。甲状腺自体移植可以避免终生接受甲状腺激素替代治疗,而终生接受甲状腺激素替代治疗可能会产生一些弊端,如破坏脂质代谢、冠心病、不依从性和吸收不良等。甲状腺自体移植还可以保留甲状腺激素分泌的内在自动调节机制、甲状腺自体移植可以避免在复发性甲状腺肿或甲状腺功能亢进症的颈部手术部位进行再次手术,因为再次手术可能会导致较高的并发症发生率。异位甲状腺自体移植术仍不是一种流行的技术,有关其长期疗效和安全性的数据也很有限。一些研究报告称,甲状腺植入物在存活率和功能方面取得了令人满意的结果,但患者人数和随访时间都很短。此外,关于移植的最佳部位、大小和数量,以及该手术的适应症和禁忌症也存在一些挑战和争议。
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引用次数: 0
Correlating preoperative clinicopathological factors with skin and/ or nipple–areola complex tumor involvement in postmastectomy specimens 术前临床病理学因素与乳房切除术后标本中皮肤和/或乳头乳晕复合体肿瘤受累的相关性
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.274248.1006
Mohamed Mahmoud Ezzat, Mohamed Adel Mohamed, Yasser Baz, Gehad Ahmed, Manal M. El Mahdy
. ABSTRACT Background: Breast cancer is the most commonly diagnosed cancer in women. Breast-conserving surgery is a common standard for treating many breast cancer patients. However, MRM (Modified radical mastectomy) is still done in ⁓ 30 % of patients undergoing surgeries. Our goal of the study is to identify factors that predict histopathological retro-areolar ducts and skin lymphatics tumor involvement, as well as to formulate bases extending the indication of skin sparing, especially nipple–areola complex (NAC) sparing mastectomy. Patients and Methods: The study is an observational analytic study conducted on 145 cases. Inclusion criteria of the study are females sex, aged more than 18 years with locoregional breast disease who are candidates for MRM. Exclusion criteria are cases with grossly involved NAC, inflammatory breast cancer, skin ulceration, and nodules, Paget’s disease of the nipple, and candidates for conservative breast surgery. Preoperatively, all patients were subjected to a triple assessment of the breast cancer. Postoperatively, all mastectomy specimens are sent for the histopathological assessment. Results: By univariate analysis, factors significantly affecting skin and NAC tumor involvement were age, tumor size, multifocality, nodal metastasis, histological grade, localized skin edema (peau d’orange), and lymphovascular invasion. By multivariate analysis, factors significantly increasing skin and NAC tumor involvement were nodal metastasis, localized skin edema, unexposure to neoadjuvant chemotherapy, and HER2 neo positive cases. Conclusion: We can extend indications of SSM (Skin sparing mastectomy) in cases with negative nodal metastasis and absence of localized skin edema, who were exposed to neoadjuvant chemotherapy and HER2 neo negative cases.
.摘要 背景:乳腺癌是女性最常确诊的癌症。保乳手术是治疗许多乳腺癌患者的通用标准。然而,仍有 30% 的患者接受 MRM(改良根治性乳房切除术)手术。我们的研究目标是确定组织病理学乳晕后导管和皮肤淋巴管肿瘤受累的预测因素,并制定扩大皮肤切除术,尤其是乳头乳晕复合体(NAC)切除术适应症的依据。患者和方法:本研究是一项观察性分析研究,共 145 例。研究的纳入标准为女性,年龄在 18 岁以上,患有局部乳腺疾病,适合进行 MRM 切除术。排除标准是有严重受累的乳腺增生症、炎症性乳腺癌、皮肤溃疡和结节、乳头帕吉特氏病以及保守性乳腺手术的患者。术前,所有患者都接受了乳腺癌三联评估。术后,所有乳房切除术标本均送去进行组织病理学评估。结果通过单变量分析,年龄、肿瘤大小、多发性、结节转移、组织学分级、局部皮肤水肿(橘皮样)和淋巴管侵犯等因素对皮肤和NAC肿瘤受累有明显影响。通过多变量分析,结节转移、局部皮肤水肿、未接受新辅助化疗和HER2新阳性病例是明显增加皮肤和NAC肿瘤受累的因素。结论对于结节转移阴性、无局部皮肤水肿、接受过新辅助化疗和HER2新阴性的病例,我们可以扩大保肤乳房切除术(SSM)的适应症。
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引用次数: 0
Laparoscopic Hartmann reversal: A single center experience in a developing country 腹腔镜哈特曼逆转术:发展中国家的单中心经验
Pub Date : 2024-07-01 DOI: 10.21608/ejsur.2024.357125
Emad M. Abdelrahman, Sherif M. ElKaffas, Mohamed I. Abuelnasr
. ABSTRACT Background: In colorectal surgery, one of the trickiest techniques is the Hartmann reversal. The rate of anastomosis leaking varies. Minimally invasive surgeries like laparoscopic Hartmann reversal (LHR) have become more popular because of lower morbidities. The aim of this study was to report our institutional experience in LHR. Patients and Methods: The current prospective randomized study included 62 patients who were eligible for HR. Patients were randomly allocated into two equal groups. Group A (n=31) underwent LHR, while group B underwent open Hartmann reversal. Follow-up was planned for at least 6 months. Results: The mean age was 45.72±15.12 and 42.66±14.91 in groups A and B, respectively. There was a statistically significant longer mean operative time with more mean blood loss in group B ( P≤0.001 ) with a significantly longer hospital stay. The postoperative complications, including wound infection, dehiscence, seroma, intestinal leak, ileus, and incisional hernia, were evident in group B when compared to group A ( P≤0.001 ). Conclusion: Well-chosen patient makes (HR) a safe and beneficial technique for improving a patient’s quality of life. Patients can get substantial benefits with minimally invasive procedures, such as a quicker recovery with fewer operating hours, less projected blood loss, a shorter time to flatus, less pain following surgery, and a shorter hospital stay.
.摘要 背景:在结直肠手术中,哈特曼翻转术是最棘手的技术之一。吻合口的渗漏率各不相同。腹腔镜哈特曼逆转术(LHR)等微创手术因发病率较低而越来越受欢迎。本研究旨在报告本院在 LHR 方面的经验。患者和方法:本前瞻性随机研究包括 62 名符合 HR 条件的患者。患者被随机分配为两组。A 组(31 人)接受 LHR,B 组接受开放哈特曼逆转术。计划随访至少 6 个月。结果A 组和 B 组的平均年龄分别为(45.72±15.12)岁和(42.66±14.91)岁。B组平均手术时间更长,平均失血量更多,差异有统计学意义(P≤0.001),住院时间明显更长。与 A 组相比,B 组的术后并发症包括伤口感染、裂开、血清肿、肠漏、回肠炎和切口疝更为明显(P≤0.001)。结论为患者精心选择的微创手术(HR)是一项安全、有益的技术,可提高患者的生活质量。患者可从微创手术中获益良多,如手术时间更短,恢复更快,预计失血量更少,排便时间更短,术后疼痛更轻,住院时间更短。
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The Egyptian Journal of Surgery
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