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Quantifying Self-Reported Adverse Drug Events on Twitter: Signal and Topic Analysis 量化Twitter上自我报告的药物不良事件:信号和话题分析
Pub Date : 2016-07-11 DOI: 10.1145/2930971.2930977
Vassilis Plachouras, Jochen L. Leidner, Andrew G. Garrow
When a drug that is sold exhibits side effects, a well functioning ecosystem of pharmaceutical drug suppliers includes responsive regulators and pharmaceutical companies. Existing systems for monitoring adverse drug events, such as the Federal Adverse Events Reporting System (FAERS) in the US, have shown limited effectiveness due to the lack of incentives for healthcare professionals and patients. While social media present opportunities to mine information about adverse events in near real-time, there are still important questions to be answered in order to understand their impact on pharmacovigilance. First, it is not known how many relevant social media posts occur per day on platforms like Twitter, i.e., whether there is "enough signal" for a post-market pharmacovigilance program based on Twitter mining. Second, it is not known what other topics are discussed by users in posts mentioning pharmaceutical drugs. In this paper, we outline how social media can be used as a human sensor for drug use monitoring. We introduce a large-scale, near real-time system for computational pharmacovigilance, and use our system to estimate the order of magnitude of the volume of daily self-reported pharmaceutical drug side effect tweets. The processing pipeline comprises a set of cascaded filters, followed by a supervised machine learning classifier. The cascaded filters quickly reduce the volume to a manageable sub-stream, from which a Support Vector Machine (SVM) based classifier identifies adverse events based on a rich set of features taking into account surface-textual properties, as well as domain knowledge about drugs, side effects and the Twitter medium. Using a dataset of 10,000 manually annotated tweets, a SVM classifier achieves F1=60.4% and AUC=0.894. The yield of the classifier for a drug universe comprising 2,600 keywords is 721 tweets per day. We also investigate what other topics are discussed in the posts mentioning pharmaceutical drugs. We conclude by suggesting an ecosystem where regulators and pharmaceutical companies utilize social media to obtain feedback about consequences of pharmaceutical drug use.
当销售的药物显示出副作用时,一个运作良好的药物供应商生态系统包括负责任的监管机构和制药公司。现有的药物不良事件监测系统,如美国的联邦不良事件报告系统(FAERS),由于缺乏对医疗保健专业人员和患者的激励,显示出有限的有效性。虽然社交媒体提供了近乎实时地挖掘不良事件信息的机会,但为了了解它们对药物警戒的影响,仍然有重要的问题需要回答。首先,不知道Twitter等平台上每天有多少相关的社交媒体帖子,也就是说,是否有“足够的信号”来开展基于Twitter挖掘的上市后药物警戒项目。其次,不知道用户在提到药品的帖子中还讨论了哪些话题。在本文中,我们概述了如何将社交媒体用作药物使用监测的人体传感器。我们引入了一个大规模的、接近实时的计算药物警戒系统,并使用我们的系统来估计每天自我报告药物副作用的推文的数量。处理管道包括一组级联过滤器,然后是一个监督机器学习分类器。级联过滤器迅速将体积减少到一个可管理的子流,其中基于支持向量机(SVM)的分类器基于一组丰富的特征来识别不良事件,考虑到表面文本属性,以及关于药物、副作用和Twitter媒体的领域知识。使用10000条人工标注推文的数据集,SVM分类器实现F1=60.4%, AUC=0.894。对于包含2600个关键词的药物领域,分类器的产出是每天721条tweet。我们也调查了在提到药物的帖子中讨论的其他话题。最后,我们建议建立一个生态系统,监管机构和制药公司利用社交媒体获得有关药物使用后果的反馈。
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引用次数: 22
Non-public eParticipation in Social Media Spaces 社会媒体空间中的非公众参与
Pub Date : 2016-07-11 DOI: 10.1145/2930971.2930974
Ella Taylor-Smith, Colin F. Smith
This paper focuses on the importance of non-public social media spaces in contemporary democratic participation at the grassroots level, based on case studies of citizen-led, community and activist groups. The research pilots the concept of participation spaces to reify online and offline contexts where people participate in democracy. Participation spaces include social media presences, websites, blogs, email, paper media, and physical spaces. This approach enables the parallel study of diverse spaces (more or less public; on and offline). Participation spaces were investigated across three local groups, through interviews and participant observation; then modelled as Socio-Technical Interaction Networks (STINs) [1]. This research provides an alternative and richer picture of social media use, within eParticipation, to studies solely based on public Internet content, such as data sets of tweets. In the participation spaces studies most communication takes place in non-public contexts, such as closed Facebook groups, email, and face-to-face meetings. Non-public social media spaces are particularly effective in supporting collaboration between people from diverse social groups. These spaces can be understood as boundary objects [2] and play strong roles in democracy.
本文通过对公民主导、社区和活动家团体的案例研究,关注非公共社交媒体空间在当代基层民主参与中的重要性。该研究试点了参与空间的概念,以具体化人们参与民主的在线和离线环境。参与空间包括社交媒体、网站、博客、电子邮件、纸质媒体和物理空间。这种方法可以并行研究不同的空间(或多或少是公共的;在线和离线)。通过访谈和参与者观察,对三个当地群体的参与空间进行了调查;然后将其建模为社会技术交互网络(STINs)[1]。这项研究提供了另一种更丰富的社交媒体使用情况,在eParticipation中,仅基于公共互联网内容(如推文数据集)的研究。在参与空间研究中,大多数交流发生在非公共环境中,如封闭的Facebook群组、电子邮件和面对面的会议。非公共社交媒体空间在支持不同社会群体之间的协作方面特别有效。这些空间可以被理解为边界对象[2],在民主中发挥着强大的作用。
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引用次数: 3
The Social Structuration of Six Major Social Media Platforms in the United Kingdom: Facebook, LinkedIn, Twitter, Instagram, Google+ and Pinterest 英国六大社交媒体平台的社会结构:Facebook, LinkedIn, Twitter, Instagram, Google+和Pinterest
Pub Date : 2016-07-11 DOI: 10.1145/2930971.2930979
Grant Blank, C. Lutz
Sociological studies on the Internet have often examined digital inequalities. These studies show how Internet access, skills, uses and outcomes vary between different population segments. However, we know more about social inequalities in general Internet use than in social media use. Especially, we lack differentiated statistical evidence of the social profiles of distinct social media platforms. To address this issue, we use a large survey data set in the United Kingdom and investigate the social structuration of six major social media platforms. We find that age and socio-economic status are driving forces of several -- but not all -- of these platforms. Aggregating platform adoption into a general measure of social media use blurs some of the subtleties of more fine-grained indicators, namely platform uses and specific activities, such as status updating and commenting.
关于互联网的社会学研究经常考察数字不平等。这些研究表明,互联网的接入、技能、使用和结果在不同人群之间存在差异。然而,与社交媒体的使用相比,我们更了解互联网使用中的社会不平等。特别是,我们缺乏不同社交媒体平台的社会概况的差异化统计证据。为了解决这个问题,我们使用了英国的大型调查数据集,调查了六大社交媒体平台的社会结构。我们发现,年龄和社会经济地位是这些平台中几个(但不是全部)的驱动因素。将平台采用率汇总到社交媒体使用的一般衡量标准中,模糊了一些更细粒度指标的微妙之处,即平台使用和特定活动,如状态更新和评论。
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引用次数: 17
Relationships form so quickly that you won't cherish them: Mobile Dating Apps and the Culture of Instantaneous Relationships 关系形成得如此之快,以至于你不会珍惜它们:手机约会应用和即时关系文化
Pub Date : 2016-07-11 DOI: 10.1145/2930971.2930973
T. E. D. Yeo, Tsz Hin Fung
Mobile dating apps with geolocative function have gained popularity for fostering social, romantic and sexual connections between proximate strangers. Focusing on the experience of social time, this paper sheds light on users' experience on two popular gay mobile dating apps, namely Grindr and Jack'd. Based on in-depth interviews and focus-group discussions with 74 young gay men in Hong Kong, this paper identifies that the tempo and sequence produced by the specific affordances of apps are important to understanding users' experience. Specifically, accelerated tempo of interactions facilitated by constant connectivity, ubiquitous computing, geolocative function, and the apps' messaging system was seen to entail instantaneous and ephemeral relationships. The interface design, which foregrounds profile photos and backgrounds textual self-descriptions, structures the sequence of browsing and screening in a way that prioritizes physical appearance. This design feature was perceived to privilege users seeking casual hook-ups. These findings suggest that the temporality of browsing and exchange on apps is incongruous with the temporal norms prescribing formation of friendship and long-term romance. The violation of these normative expectations affects the perceived quality and satisfaction of app use, resulting in users' frustrations.
具有地理定位功能的手机约会应用程序因促进近邻陌生人之间的社交、浪漫和性联系而受到欢迎。本文以社交时间的体验为重点,揭示了两款流行的同性恋手机约会应用Grindr和Jack'd的用户体验。基于对74名香港年轻男同性恋者的深度访谈和焦点小组讨论,本文认为应用程序的特定功能所产生的节奏和顺序对于理解用户体验非常重要。具体来说,持续的连接、无处不在的计算、地理定位功能和应用程序的消息传递系统加速了互动的节奏,被认为需要即时和短暂的关系。其界面设计突出了个人资料照片和背景文字自我描述,以一种优先考虑外观的方式构建了浏览和筛选的顺序。这一设计功能被认为是为寻求随意联系的用户提供特权。这些发现表明,在应用程序上浏览和交流的短暂性与规定友谊和长期浪漫关系形成的时间规范不协调。违反这些规范期望会影响应用使用的感知质量和满意度,从而导致用户的挫败感。
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引用次数: 13
Accuracy Of User-Contributed Image Tagging In Flickr: A Natural Disaster Case Study Flickr中用户贡献图像标记的准确性:一个自然灾害案例研究
Pub Date : 2016-07-11 DOI: 10.1145/2930971.2930986
George Panteras, Xu Lu, A. Croitoru, A. Crooks, A. Stefanidis
Social media platforms have become extremely popular during the past few years, presenting an alternate, and often preferred, avenue for information dissemination within massive global communities. Such user-generated multimedia content is emerging as a critical source of information for a variety of applications, and particularly during times of crisis. In order to fully explore this potential, there is a need to better assess, and improve when possible, the accuracy of such information. This paper addresses this issue by focusing in particular on user-contributed image tagging in Flickr. We use as case study a natural disaster event (wildfire), and assess the reliability of user-generated tags. Furthermore, we compare these data to the results of a content-based annotation approach in order to assess the potential performance of an alternative, user-independent, automated approach to annotate such imagery. Our results show that Flickr user annotations can be considered quite reliable (at the level of ~50%), and that using a spatially distributed training dataset for our content-based image retrieval (CBIR) annotation process improves the performance of the content-based image labeling (to the level of ~75%).
在过去的几年里,社交媒体平台变得非常受欢迎,为大规模的全球社区提供了一种替代的、通常是首选的信息传播途径。这种用户生成的多媒体内容正在成为各种应用程序的关键信息来源,特别是在危机时期。为了充分发掘这种潜力,有必要更好地评价和尽可能改进这种资料的准确性。本文通过特别关注Flickr中用户贡献的图像标记来解决这个问题。我们使用自然灾害事件(野火)作为案例研究,并评估用户生成标签的可靠性。此外,我们将这些数据与基于内容的注释方法的结果进行比较,以评估另一种独立于用户的自动化方法对此类图像进行注释的潜在性能。我们的结果表明,Flickr用户注释可以被认为是相当可靠的(在~50%的水平上),并且使用空间分布式训练数据集进行基于内容的图像检索(CBIR)注释过程可以提高基于内容的图像标记的性能(达到~75%的水平)。
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引用次数: 5
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Proceedings of the 7th 2016 International Conference on Social Media & Society
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