Betting odds for possible carriers of haemophilia have been calculated using data derived from normal and known carrier populations. For each possible carrier the concentration of factor VIII-related antigen and factor VIII biological activity was measured and used to determine the probability of the individual being a carrier. The calculations indicated that, of the 32 possible carriers, 11 were likely to be normal (odds of more than 5:1) while 11 were likely to be haemophilia carriers (again odds of more than 5:1).
{"title":"Calculation of predictive odds for possible carriers of heamophilia.","authors":"C R Prentice, C D Forbes, S Morrice, A D McLaren","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Betting odds for possible carriers of haemophilia have been calculated using data derived from normal and known carrier populations. For each possible carrier the concentration of factor VIII-related antigen and factor VIII biological activity was measured and used to determine the probability of the individual being a carrier. The calculations indicated that, of the 32 possible carriers, 11 were likely to be normal (odds of more than 5:1) while 11 were likely to be haemophilia carriers (again odds of more than 5:1).</p>","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 3","pages":"740-7"},"PeriodicalIF":0.0,"publicationDate":"1975-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12387003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter: A more uniform measurement of factor VIII inhibitors.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 3","pages":"869-72"},"PeriodicalIF":0.0,"publicationDate":"1975-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12387012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter: The buffering of anticoagulants for blood collection.","authors":"R Godfrey, T W Barrowcliffe","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 3","pages":"879-82"},"PeriodicalIF":0.0,"publicationDate":"1975-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12387016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On the structure of fibrinogen related to its plasmic degradation products D and E.","authors":"G Marguerie, G Hudry-Clergeon, M Suscillon","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 3","pages":"664-70"},"PeriodicalIF":0.0,"publicationDate":"1975-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11348706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings: Fibrinogen degradation of normal and fibrinolytic plasma.","authors":"M F Scully, V V Kakkar","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"584"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11276545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular biology of human plasminogen. I. Physiochemical properties and microheterogeneity.","authors":"D Collen, L de Maeyer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"396-402"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11225591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings: Indications and results of fibrinolytic treatment with streptokinase in chronic arterial stenoses and occlusions; a multicentre trial of 708 patients.","authors":"R Schmutzler","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"569"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12285380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings: Comparative investigations on time dependent changes of enhanced aggregation.","authors":"I Scharrer, K Breddin, M Ziemen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"575"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12375110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号